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CN110559203A - Low-irritation cleaning composition and preparation method thereof - Google Patents

Low-irritation cleaning composition and preparation method thereof Download PDF

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Publication number
CN110559203A
CN110559203A CN201910910378.8A CN201910910378A CN110559203A CN 110559203 A CN110559203 A CN 110559203A CN 201910910378 A CN201910910378 A CN 201910910378A CN 110559203 A CN110559203 A CN 110559203A
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CN
China
Prior art keywords
alcohol
composition
surfactant
sodium
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910910378.8A
Other languages
Chinese (zh)
Inventor
罗财通
崔英云
李传茂
张伟杰
张楚标
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangdong Dan Zi Group Co Ltd
GUANGZHOU BAIYUN LIANJIA FINE CHEMICALS FACTORY
Guangzhou Keneng Cosmetic Research Co Ltd
Original Assignee
Guangdong Dan Zi Group Co Ltd
GUANGZHOU BAIYUN LIANJIA FINE CHEMICALS FACTORY
Guangzhou Keneng Cosmetic Research Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangdong Dan Zi Group Co Ltd, GUANGZHOU BAIYUN LIANJIA FINE CHEMICALS FACTORY, Guangzhou Keneng Cosmetic Research Co Ltd filed Critical Guangdong Dan Zi Group Co Ltd
Priority to CN201910910378.8A priority Critical patent/CN110559203A/en
Publication of CN110559203A publication Critical patent/CN110559203A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/342Alcohols having more than seven atoms in an unbroken chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/442Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

The invention belongs to the technical field of cosmetics, and particularly relates to a low-irritation cleaning composition. The cleaning composition of the present invention comprises a surfactant and a fatty alcohol. The surfactant and the fatty alcohol are compounded, so that the dosage of the surfactant is effectively reduced, and meanwhile, the fatty alcohol can be inserted between hydrophilic groups of micelles formed by the surfactant to form a larger micelle structure, so that the irritation of the surfactant is further reduced, and the preparation method has the characteristics of being mild, non-irritant, suitable for sensitive muscles and the like.

Description

Low-irritation cleaning composition and preparation method thereof
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to a low-irritation cleaning composition and a preparation method thereof.
Background
Currently, commercially available facial cleansers usually contain 15% -30% of surfactant as a core cleaning component, and some facial cleansers contain highly irritating surfactant or do not reduce the irritation of the surfactant through an effective compounding method, so that the skin barrier function is damaged after long-term use.
The stratum corneum in the skin serves as a protective function between the human body and the external environment, lipids are important components of the lipid barrier built in the stratum corneum just like bricks, but excessive cleaning of surfactants can cause lipid loss. Once the lipid barrier is damaged, the skin's moisture retention capacity is reduced, causing symptoms such as tightness, dryness, peeling, erythema and the like after washing, and even easily causing the generation of sensitive skin. Surfactants may also denature proteins until the surfactant enters the intercellular space, allowing the intercellular material to be dissolved.
Until now, most of the commercial facial cleansing products are still mainstream with high content of fatty acid soap. Although giving good cleaning effect, abundant foam, and reduced irritation by adding quaternary ammonium salts or water-soluble oils and fats. But still not mild enough due to the high surfactant content.
The existing face cleaning products still have the following common problems: 1. the surfactant content is high, and stimulation is easy to generate on sensitive skin; 2. when the dirt of the skin is cleaned, some skin components which should not be cleaned are cleaned, and even the skin is harmful; 3. the abundant foam, while increasing the contact area of the surfactant with the skin, also easily enters the eye, irritating the eye.
Disclosure of Invention
The object of the present invention is to provide a low irritancy cleansing composition.
The invention also aims to provide the application of the low-irritation cleaning composition in preparing products for cleaning skin and hair.
It is also an object of the present invention to provide a process for the preparation of a low irritancy cleansing composition.
The invention provides a cleaning composition which has low surfactant content and reduces the irritation of a surfactant by compounding fatty alcohol. The fatty alcohol can be inserted between hydrophilic groups of the micelle formed by the surfactant to form a larger micelle structure, so that the irritation of the surfactant is reduced, and the surfactant is suitable for sensitive skin.
in one embodiment, there is provided a cleaning composition comprising the following components in weight percent: 0.5-10% of surfactant and 1-10% of fatty alcohol; preferably, 0.5-3% of a surfactant; preferably, the fatty alcohol is 1-5%.
In one embodiment, there is also provided a cleaning composition, the surfactant being a combination of one or more of sodium laureth-3 sulfate, sodium cocoyl glycinate, lauramidopropyl betaine, sodium methylcocoyltaurate, sodium lauryl sulfate, sodium lauroamphoacetate, disodium lauriminodiacetate, lauryl glucoside, sodium lauroyl glutamate; preferably one or more of sodium laureth-3 sulfate, lauramidopropyl betaine and lauryl glucoside; more preferably lauramidopropyl betaine.
In one embodiment, there is also provided a cleaning composition, the fatty alcohol being a combination of one or more of lauryl alcohol, stearyl alcohol, cetyl alcohol, cetearyl alcohol, behenyl alcohol; preferably one or more of lauryl alcohol, cetostearyl alcohol and behenyl alcohol; more preferably cetearyl alcohol.
in one embodiment, there is also provided a cleaning composition further comprising in weight percent: 1-15% of polyol; preferably 3 to 8%; 0.2 to 1 percent of preservative; preferably 0.3 to 0.6; the balance of deionized water.
in one embodiment, there is also provided a cleaning composition, the polyol being a combination of one or more of glycerin, propylene glycol, 1, 3-propanediol, 1, 3-butanediol, dipropylene glycol, sorbitol, diglycerin; preferably one or more of glycerol, 1, 3-propylene glycol and sorbitol; more preferably glycerol.
in one embodiment, there is also provided a cleaning composition, the preservative being a combination of one or more of p-hydroxyacetophenone, phenoxyethanol, chlorphenesin, methylparaben, sorbitan octanoate, benzoic acid, gluconolactone, sodium benzoate; preferably one or more of phenoxyethanol and chlorphenesin; more preferably phenoxyethanol.
In one embodiment, a cleansing composition is also provided, and may be used in the form of a cleansing product including facial cleanser, facial gel, facial lotion, and facial cream.
in one embodiment, the use of a cleansing composition in the preparation of a skin and hair cleansing product is also provided.
in one embodiment, there is also provided a method of making a cleaning composition comprising the steps of:
(1) Preparing raw materials according to the composition;
(2) adding water, polyalcohol and surfactant into an emulsifying pot, stirring for dissolving, heating to 85-95 deg.C, and keeping the temperature for 10-20 min; preferably, heating to 90 ℃; preferably, the incubation is for 15 minutes;
(3) putting fatty alcohol into an emulsifying pot, and stirring, dissolving and dispersing uniformly at the temperature of 80-90 ℃; emulsifying at a homogenizing rotating speed of 2000-3000 rpm for 1-5 minutes, and stirring at a rotating speed of 20-30 rpm for 5 minutes after emulsification to start cooling;
(4) When the temperature is reduced to 40-45 ℃, adding a preservative into the emulsifying pot, and uniformly stirring;
(5) Vacuumizing, stirring uniformly, cooling to 30-40 ℃, and discharging; preferably, the temperature is reduced to 35 ℃.
The invention has the following beneficial effects:
(1) And (2) mildness: the cleaning composition has lower surfactant content than common cleaning products, and the cleaning process is milder.
(2) no stimulation: in the cleaning composition, the stimulation of the surfactant is further reduced by compounding the surfactant and the fatty alcohol, and the cleaning composition is suitable for sensitive skin.
(3) excellent skin feel after cleansing: the cleaning composition of the invention can not bring away skin moisture additionally after cleaning the skin, and the moisture content of the skin is hardly reduced obviously after 8 hours of using the cleaning composition of the invention, and the skin has no tight feeling and has excellent skin feeling.
(4) the stability is good: the compositions of the present invention exhibit good stability, whether at room temperature, high temperature, low temperature, or in a cyclic temperature system.
Detailed Description
The technical solutions of the present invention are further illustrated by the following specific examples, which do not represent limitations to the scope of the present invention. Insubstantial modifications and adaptations of the present invention by others of the concepts fall within the scope of the invention.
Examples 1-4 facial cleansers containing compositions of different Components
TABLE 1 examples of the different components (unit: wt%)
the preparation method comprises the following steps:
(1) adding water, polyalcohol and surfactant into an emulsifying pot, stirring for dissolving, heating to 90 deg.C, and keeping the temperature for 15 min.
(2) Putting fatty alcohol into an emulsifying pot, and stirring, dissolving and dispersing uniformly at the temperature of 80-90 ℃; emulsifying at a homogenizing rotation speed of 1000-3000 rpm for 1-5 minutes, and stirring at a rotation speed of 20-30 rpm for 5 minutes after emulsification to start cooling.
(3) When the temperature is reduced to 40-45 ℃, adding a preservative into the emulsifying pot, and uniformly stirring;
(4) Vacuumizing, stirring, cooling to 35 deg.C, and discharging.
Comparative examples 1 to 4 face washes containing different components
TABLE 2 comparative examples of different components (unit: wt%)
sodium laurate and sodium oleate are also commonly used surfactants in the art, and comparative examples investigate the effect of different surfactants on the effectiveness of a facial cleanser.
comparative examples 1 to 4 were prepared in the same manner as in examples 1 to 4.
Physical and chemical tests:
The results of the physicochemical tests conducted on examples 1 to 4 and comparative examples 1 to 4 were as follows:
Appearance: white milky.
pH value: 5.5-8.
Comparison of stability of examples and comparative examples
To examine the stability of the composition of the present invention, 120g of the compositions of examples 1 to 4 and comparative examples 1 to 4 were taken and placed in a room temperature, a incubator at 48 deg.C, a refrigerator at-20 deg.C and a circulation oven at-20-25-48 deg.C, respectively, and then the stability was observed for 1 month. The observation results are shown in table 3 below.
Table 3 stability test results
As can be seen from the results in Table 3 above, examples 1 to 4 of the present invention and comparative examples 3 to 4 showed good dosage form stability. Comparative examples 1-2 show poor stability.
Patch test
1. Experimental methods
1.1 test materials
The test substance: the compositions of examples 1-4, the compositions of comparative examples 3-4 and either of the two commercially available conventional facial cleanser products.
any of the commercially available common facial cleansers 1 is in the ingredient table: water, glycerol, (sodium cocoyl glycinate, water), (cocamidopropyl betaine, water, sodium chloride), (water, disodium lauryl sulfosuccinate), citric acid, (decyl glucoside, water), polyethylene glycol-14M, perfume, disodium EDTA, niacinamide, wine extract, (DMDM hydantoin, water), (schizosaccharomyces filament fermentation product filtrate, butylene glycol, citric acid, water).
Any of the commercially available ordinary face cleansers 2 ingredient tables: water, glycerol, stearic acid, myristic acid, disodium laureth sulfosuccinate, potassium hydroxide, lauric acid, palmitic acid, (potassium cetyl phosphate, glyceryl stearate, PEG-40 sorbitan stearate), sodium methyl cocoyl taurate, ethylene glycol distearate, disodium EDTA, (propylene glycol, bis (hydroxymethyl) imidazolidinyl urea, iodopropynyl butylcarbamate), methylparaben, propylparaben, perfume.
a spot tester: (Shanghai sanitation Material works Co., Ltd. +140801)
testing an instrument: [ quantitative piston gun (Microman M100+ GILSON LCO5239) single channel liquid transfer device (Transferpette +08N33275) ]
2. Test method
Subject: a total of 30 subjects; minimum age 23 years, maximum age 35 years; average age 27 ± 5.1 year old volunteers met the enrollment criteria.
The spot-sticking test method comprises the following steps: selecting a qualified spot tester, placing 0.020-0.025g (facial cleanser) of a tested object in the spot tester by a closed spot test method, externally applying a medical adhesive tape to the back of the tested object, removing the tested object after 24 hours, observing skin reactions 0.5, 24 and 48 hours after the spot is removed respectively, and recording the results according to the skin reaction grading standard in technical Specification for safety of cosmetics (2015 edition).
3. Basis of examination
The fifth part of the human skin closed patch test skin adverse reaction grading standard of the technical Specification for cosmetic safety (2015 edition) shows the detection results as shown in Table 3.
The specific reaction degree grading grade is as follows:
0 negative reaction;
1 suspicious reaction: only faint erythema;
2 weak positive reaction (erythema reaction): erythema, infiltration, edema, and possibly papules;
Strong positive reaction (herpes reaction): erythema, infiltration, edema, papules, herpes: the reaction may be beyond the test area;
4 very strong positive reaction (fusogenic herpes reaction): obvious erythema, severe infiltration, edema, fusional herpes: the reaction goes beyond the test area.
Table 4 results of the human skin occlusive patch test of the compositions of examples 1-4, comparative examples 3, 4 and either of the two commercial conventional facial cleansers
From the above conclusion of table 4, it can be seen that: the result of a closed patch test on human skin shows that 0 of 30 people have positive reaction by using the facial cleanser prepared by the invention, and the test object does not cause adverse reaction on the skin of the batch of test subjects according to the regulation in technical Specification for cosmetic safety (2015 edition). The results show that examples 1-4 of the present invention are non-irritating to the skin and have no positive response. The positive reactions of different degrees occurred in comparative examples 3-4 and either of the two commercially available facial cleansers, indicating that the present invention is milder and less irritating than the comparative examples and either of the two commercially available facial cleansers.
Efficacy test
The principle of moisture measurement by means of the Corneometer CM825, a german CK skin moisture tester, is based on the fact that the dielectric constant (<7) of water and other substances varies considerably, and that, depending on the moisture content, a suitably shaped measuring capacitor changes with the change in the capacitance of the skin, which is within the measurement range, so that the moisture content of the skin can be measured. The degree of damage to the skin barrier is indirectly derived from the moisture content. The high moisture content after face cleaning indicates that the face cleaning milk has little influence on normal physiological lipid of the skin and cannot damage the skin barrier, and if the moisture content is reduced, the skin physiological lipid is excessively eluted and the skin barrier is damaged.
The main technical parameters are as follows:
1. The test principle is as follows: the capacitive principle;
2. Area of the test head: 7X 7mm 2;
3. And (3) probe parameters: a length of about 11 cm;
4. Measurement time frequency: 0.9-1.2 MHZ;
5. and (3) testing pressure: 1.1-1.5N;
6. precision: plus or minus 3 percent;
7. Numerical ranges: 0 to 130;
8. weight: about 41 g.
7 volunteers were given the above-mentioned examples 1-5 and two commercially available ordinary face cleansers using a German CK skin moisture tester CM 825. Before use, the skin moisture content of each subject was measured under conditions of constant temperature and constant humidity (21 ℃ and 40% humidity) with a skin moisture tester, and as a reference value, T0 immediately after application and changes in the skin moisture content 2 hours, 4 hours, and 8 hours after application were measured, and the test results are shown in table 5.
TABLE 5
as can be seen from the test results of Table 5, in the case of using the facial cleansers of examples 1-4, the skin moisture content decreased less than that of any of the conventional facial cleansers on the comparative market within 8 hours after the use. Comparative examples 3-4, the skin moisture content decreased by more than 10% after 8 hours, while the compositions of the present invention were only within 5%.
In addition, at the end of the test, the subjects were subjected to a questionnaire of the skin tightening effect. The effect was evaluated using a 5-point scale, the evaluation values (5-point scale) were averaged and are shown in table 6 below.
TABLE 6
as can be seen from the results in Table 6 above, the present invention provides a better after-use feel of the cleanser than the comparative example cleanser and the commercial cleanser, and the questionnaire shows that the cleanser of the present invention has no feeling of skin tightness when used, while the comparative example cleanser and the commercial cleanser provide more than a certain degree of tightness to the user to different degrees.
the above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents and are included in the scope of the present invention.

Claims (9)

1. a cleaning composition characterized by comprising the following components in weight percent: 0.5-10% of surfactant and 1-10% of fatty alcohol;
Preferably, 0.5-3% of a surfactant;
Preferably, the fatty alcohol is 1-5%.
2. The composition of claim 1, wherein the surfactant is a combination of one or more of sodium laureth-3 sulfate, sodium cocoyl glycinate, lauramidopropyl betaine, sodium methylcocoyltaurate, sodium lauryl sulfate, sodium lauroamphoacetate, disodium lauriminodiacetate, lauryl glucoside, sodium lauroyl glutamate; preferably one or more of sodium laureth-3 sulfate, lauramidopropyl betaine and lauryl glucoside; more preferably lauramidopropyl betaine.
3. The composition of claim 1, wherein the fatty alcohol is one or more of lauryl alcohol, stearyl alcohol, cetyl alcohol, cetearyl alcohol, behenyl alcohol in combination; preferably one or more of lauryl alcohol, cetostearyl alcohol and behenyl alcohol; more preferably cetearyl alcohol.
4. The composition of claim 1, further comprising in weight percent:
1-15% of polyol; preferably 3 to 8%;
0.2 to 1 percent of preservative; preferably 0.3-0.6%;
the balance of deionized water.
5. The composition of claim 4, wherein the polyol is a combination of one or more of glycerol, propylene glycol, 1, 3-propanediol, 1, 3-butanediol, dipropylene glycol, sorbitol, diglycerol; preferably one or more of glycerol, 1, 3-propylene glycol and sorbitol; more preferably glycerol.
6. The composition of claim 4, wherein the preservative is a combination of one or more of p-hydroxyacetophenone, phenoxyethanol, chlorphenesin, methylparaben, sorbitan caprylate, benzoic acid, gluconolactone, sodium benzoate; preferably one or more of phenoxyethanol and chlorphenesin; more preferably phenoxyethanol.
7. The composition of any of claims 1-6, in the form of a cleansing product, comprising a facial cleanser, a facial gel, a facial lotion, a facial cream.
8. Use of a composition according to any of claims 1 to 6 for the preparation of a product for cleansing the skin or hair.
9. A method of preparing the composition of claim 4, comprising the steps of:
(1) Preparing raw materials according to the composition;
(2) Adding water, polyalcohol and surfactant into an emulsifying pot, stirring for dissolving, heating to 85-95 deg.C, and keeping the temperature for 10-20 min; preferably, heating to 90 ℃; preferably, the incubation is for 15 minutes;
(3) Putting fatty alcohol into an emulsifying pot, and stirring, dissolving and dispersing uniformly at the temperature of 80-90 ℃; emulsifying at a homogenizing rotating speed of 1000-3000 rpm for 1-5 minutes, and stirring at a rotating speed of 20-30 rpm for 5 minutes after emulsification to start cooling;
(4) when the temperature is reduced to 40-45 ℃, adding a preservative into the emulsifying pot, and uniformly stirring;
(5) vacuumizing, stirring uniformly, cooling to 30-40 ℃, and discharging; preferably, the temperature is reduced to 35 ℃.
CN201910910378.8A 2019-09-25 2019-09-25 Low-irritation cleaning composition and preparation method thereof Pending CN110559203A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115317390A (en) * 2022-07-04 2022-11-11 广州丝芬化妆品有限公司 Composition for reducing irritation degree of cleaning product raw materials and application thereof
CN117377459A (en) * 2021-05-26 2024-01-09 莱雅公司 Compositions for cleaning keratin materials and/or removing makeup from keratin materials

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CN104027252A (en) * 2014-06-25 2014-09-10 无锡市崇安区科技创业服务中心 Nano bentonite antibacterial cleaning milk and preparation method thereof
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Publication number Priority date Publication date Assignee Title
US6589922B1 (en) * 2001-03-08 2003-07-08 Dow Pharmaceutical Sciences Skin cleanser comprising a steareth, poloxamer, and a glyceryl monoester
CN102727397A (en) * 2011-03-30 2012-10-17 强生消费者公司 Creamy cleansing compositions
CN104027252A (en) * 2014-06-25 2014-09-10 无锡市崇安区科技创业服务中心 Nano bentonite antibacterial cleaning milk and preparation method thereof
CN106176571A (en) * 2016-09-06 2016-12-07 佛山市芊茹化妆品有限公司 A kind of natural Haircare composition and preparation method thereof of originating
CN107412010A (en) * 2017-08-29 2017-12-01 澳宝化妆品(惠州)有限公司 A kind of hair conditioner with low bubble cleaning efficacy

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Title
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117377459A (en) * 2021-05-26 2024-01-09 莱雅公司 Compositions for cleaning keratin materials and/or removing makeup from keratin materials
CN115317390A (en) * 2022-07-04 2022-11-11 广州丝芬化妆品有限公司 Composition for reducing irritation degree of cleaning product raw materials and application thereof

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