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CN110246144A - A kind of the blood vessel Enhancement Method and system of lung CT image - Google Patents

A kind of the blood vessel Enhancement Method and system of lung CT image Download PDF

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CN110246144A
CN110246144A CN201910523514.8A CN201910523514A CN110246144A CN 110246144 A CN110246144 A CN 110246144A CN 201910523514 A CN201910523514 A CN 201910523514A CN 110246144 A CN110246144 A CN 110246144A
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赵振威
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First Hospital Jinlin University
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    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/10Segmentation; Edge detection
    • G06T7/11Region-based segmentation
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/10Segmentation; Edge detection
    • G06T7/155Segmentation; Edge detection involving morphological operators
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/10Segmentation; Edge detection
    • G06T7/187Segmentation; Edge detection involving region growing; involving region merging; involving connected component labelling
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10072Tomographic images
    • G06T2207/10081Computed x-ray tomography [CT]
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30061Lung
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30101Blood vessel; Artery; Vein; Vascular

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Abstract

本发明涉及一种肺部CT图像的血管增强方法及系统,CT图像输入单元、预设分割阈值获取单元、不带血管的肺组织区域获取单元、血管阈值计算单元、初始扩散面获取单元、用于根据所述初始扩散面和血管阈值,在所述n层胸部CT图像的带血管的封闭肺组织区域内进行面扩散,获得肺血管。可以自动准确的从胸部CT图像上提取出肺血管,使医生对肺血管的观察更直观、更准确,避免了在图像上观察和诊断肺血管疾病时心脏以及骨骼的干扰,而且运算速度快时间短。

The present invention relates to a blood vessel enhancement method and system for lung CT images, including a CT image input unit, a preset segmentation threshold acquisition unit, a lung tissue area acquisition unit without blood vessels, a blood vessel threshold calculation unit, an initial diffusion surface acquisition unit, According to the initial diffusion surface and the blood vessel threshold, surface diffusion is performed in the closed lung tissue area with blood vessels in the n-layer chest CT image to obtain pulmonary blood vessels. It can automatically and accurately extract pulmonary blood vessels from chest CT images, making doctors' observation of pulmonary blood vessels more intuitive and accurate, avoiding the interference of the heart and bones when observing and diagnosing pulmonary vascular diseases on images, and the calculation speed is fast. short.

Description

一种肺部CT图像的血管增强方法及系统A blood vessel enhancement method and system for lung CT images

技术领域technical field

本发明涉及肺癌诊疗技术领域,具体是一种肺部CT图像的血管增强方法及系统。The invention relates to the technical field of diagnosis and treatment of lung cancer, in particular to a blood vessel enhancement method and system for lung CT images.

背景技术Background technique

CT是电子计算机X线断层扫描技术简称,是常用的医学影像设备。CT图像是黑白影像,以不同的灰度表示应器官和组织对X线的吸收程度。例如,在胸部CT图像上,低密度(即灰度值较低)的区域表示气管、肺实质,高密度(即灰度值较高)的区域表示血管、胸腔、骨骼等。CT可以直观的在图像上显示出病变的区域,为医生观察诊断疾病提供了方便可靠的依据。通常,CT图像是横断层面图像,为了显示整个器官,需要多个连续的层面图像。CT is the abbreviation of computer X-ray tomography technology, which is a commonly used medical imaging equipment. CT images are black and white images, with different gray levels representing the degree of absorption of X-rays by organs and tissues. For example, in a chest CT image, areas with low density (that is, low gray value) represent trachea and lung parenchyma, and areas with high density (that is, high gray value) represent blood vessels, chest cavity, bones, etc. CT can intuitively display the lesion area on the image, which provides a convenient and reliable basis for doctors to observe and diagnose diseases. Usually, CT images are cross-sectional images, and in order to display the entire organ, multiple consecutive slice images are required.

在肺部疾病的CT诊断中,通常需要扫描整个胸腔来得到肺血管图像,在扫描图像中必然存在胸腔内的骨骼以及心脏等,并且,临床医生只能通过逐层图像的观察来检查病变区域。因此,准确的从CT图像中提取出肺血管组织是排除骨骼、心脏等组织的干扰,使医生更直观的观察和诊断肺血管疾病的有效方法。In the CT diagnosis of lung diseases, it is usually necessary to scan the entire thoracic cavity to obtain pulmonary vascular images. In the scanned images, there must be bones and hearts in the thoracic cavity, and clinicians can only check the lesion area through layer-by-layer image observation. . Therefore, accurate extraction of pulmonary vascular tissue from CT images is an effective method to eliminate the interference of bone, heart and other tissues, so that doctors can observe and diagnose pulmonary vascular diseases more intuitively.

发明内容Contents of the invention

本发明所要解决的技术问题是提供一种肺部CT图像的血管增强方法及系统,以解决现有技术中存在的缺陷。The technical problem to be solved by the present invention is to provide a blood vessel enhancement method and system for lung CT images, so as to solve the defects in the prior art.

本发明解决上述技术问题的技术方案如下:The technical scheme that the present invention solves the problems of the technologies described above is as follows:

一种从胸部CT图像中提取肺血管的装置,包括:CT图像输入单元:用于接收输入CT图像;预设分割阈值获取单元:利用CT图像三维特征平均投影密度结合多尺度圆点增强进行预处理;不带血管的肺组织区域获取单元:用于在所述指定图像层上选取肺部区域的指定像素点获得初始种子点,根据所述预设分割阈值以及初始种子点,在所述n层胸部CT图像进行3D区域增长,获得不带血管的肺组织区域;血管阈值计算单元:在所述的肺组织区域进行形态学运算,获得带血管的封闭肺组织区域,计算血管阈值;初始扩散面获取单元:用于在所述指定图像层上的带血管的封闭肺组织区域查找大于血管阈值的像素点为初始标记点,获得初始扩散面;肺血管提取单元:用于根据所述初始扩散面和血管阈值,在所述n层胸部CT图像的带血管的封闭肺组织区域内进行面扩散,获得肺血管。A device for extracting pulmonary vessels from a chest CT image, comprising: a CT image input unit: used to receive an input CT image; a preset segmentation threshold acquisition unit: using the average projection density of the three-dimensional features of the CT image combined with multi-scale dot enhancement to perform prediction Processing; lung tissue area acquisition unit without blood vessels: used to select specified pixel points of the lung area on the specified image layer to obtain initial seed points, according to the preset segmentation threshold and initial seed points, in the n Perform 3D region growth on the chest CT image to obtain the lung tissue area without blood vessels; blood vessel threshold calculation unit: perform morphological operations on the lung tissue area to obtain the closed lung tissue area with blood vessels, and calculate the blood vessel threshold; initial diffusion Surface acquisition unit: used to search the closed lung tissue area with blood vessels on the specified image layer to find the pixel points larger than the blood vessel threshold as initial marker points, and obtain the initial diffusion surface; pulmonary blood vessel extraction unit: used to obtain the initial diffusion surface according to the initial diffusion surface and blood vessel thresholding, performing surface diffusion in the closed lung tissue area with blood vessels in the n-slice chest CT image to obtain pulmonary blood vessels.

一种从胸部CT图像中提取肺血管的方法,其特征在于,包括如下步骤:A method for extracting pulmonary vessels from chest CT images, comprising the steps of:

第一步:利用CT图像三维特征平均投影密度结合多尺度圆点增强进行预处理;The first step: preprocessing by using the average projection density of CT image 3D features combined with multi-scale dot enhancement;

第二步:在所述指定图像层上选取肺部区域的指定像素点获得初始种子点,根据所述预设分割阈值以及初始种子点,在所述n层胸部CT图像进行3D区域增长,获得不带血管的肺组织区域;Step 2: select specified pixel points in the lung region on the specified image layer to obtain initial seed points, and perform 3D region growth on the n-layer chest CT images according to the preset segmentation threshold and initial seed points to obtain Areas of lung tissue without blood vessels;

第三步:在所述的肺组织区域进行形态学运算,获得带血管的封闭肺组织区域,计算血管阈值;Step 3: Perform morphological calculations on the lung tissue area to obtain a closed lung tissue area with blood vessels, and calculate the blood vessel threshold;

第四步:采用只对肺结节进行聚类的策略和快速准确自适应阈值两方面优化的DBSCAN超像素序列图像聚类算法,对超像素样本进行聚类,得到序列肺结节掩膜,最终得到肺部CT的序列肺结节图像;Step 4: Using the DBSCAN superpixel sequence image clustering algorithm optimized by the strategy of clustering only pulmonary nodules and the fast and accurate adaptive threshold, cluster the superpixel samples to obtain the sequential pulmonary nodule mask, Finally, the sequential lung nodule image of lung CT is obtained;

第五步:根据所述初始扩散面和血管阈值,在所述n层胸部CT图像的带血管的封闭肺组织区域内进行面扩散,获得肺血管。Step 5: According to the initial diffusion surface and the blood vessel threshold, surface diffusion is performed in the closed lung tissue area with blood vessels in the n-layer chest CT image to obtain pulmonary blood vessels.

本发明的有益效果是:可以自动准确的从胸部CT图像上提取出肺血管,使医生对肺血管的观察更直观、更准确,避免了在图像上观察和诊断肺血管疾病时心脏以及骨骼的干扰,而且运算速度快时间短。The beneficial effects of the present invention are: the pulmonary vessels can be automatically and accurately extracted from the chest CT image, making the doctor's observation of the pulmonary vessels more intuitive and accurate, and avoiding the heart and bones when observing and diagnosing pulmonary vascular diseases on the images. Interference, and the calculation speed is fast and the time is short.

附图说明Description of drawings

图1为本发明结构示意图;Fig. 1 is a structural representation of the present invention;

具体实施方式Detailed ways

以下结合附图对本发明的原理和特征进行描述,所举实例只用于解释本发明,并非用于限定本发明的范围。The principles and features of the present invention are described below in conjunction with the accompanying drawings, and the examples given are only used to explain the present invention, and are not intended to limit the scope of the present invention.

如图1所示,一种肺部CT图像的血管增强方法及系统,包括As shown in Figure 1, a blood vessel enhancement method and system for lung CT images, including

一种从胸部CT图像中提取肺血管的装置,包括:CT图像输入单元:用于接收输入CT图像;预设分割阈值获取单元:利用CT图像三维特征平均投影密度结合多尺度圆点增强进行预处理;不带血管的肺组织区域获取单元:用于在所述指定图像层上选取肺部区域的指定像素点获得初始种子点,根据所述预设分割阈值以及初始种子点,在所述n层胸部CT图像进行3D区域增长,获得不带血管的肺组织区域;血管阈值计算单元:在所述的肺组织区域进行形态学运算,获得带血管的封闭肺组织区域,计算血管阈值;初始扩散面获取单元:用于在所述指定图像层上的带血管的封闭肺组织区域查找大于血管阈值的像素点为初始标记点,获得初始扩散面;肺血管提取单元:用于根据所述初始扩散面和血管阈值,在所述n层胸部CT图像的带血管的封闭肺组织区域内进行面扩散,获得肺血管。A device for extracting pulmonary vessels from a chest CT image, comprising: a CT image input unit: used to receive an input CT image; a preset segmentation threshold acquisition unit: using the average projection density of the three-dimensional features of the CT image combined with multi-scale dot enhancement to perform prediction Processing; lung tissue area acquisition unit without blood vessels: used to select specified pixel points of the lung area on the specified image layer to obtain initial seed points, according to the preset segmentation threshold and initial seed points, in the n Perform 3D region growth on the chest CT image to obtain the lung tissue area without blood vessels; blood vessel threshold calculation unit: perform morphological operations on the lung tissue area to obtain the closed lung tissue area with blood vessels, and calculate the blood vessel threshold; initial diffusion Surface acquisition unit: used to search the closed lung tissue area with blood vessels on the specified image layer to find the pixel points larger than the blood vessel threshold as initial marker points, and obtain the initial diffusion surface; pulmonary blood vessel extraction unit: used to obtain the initial diffusion surface according to the initial diffusion surface and blood vessel thresholding, performing surface diffusion in the closed lung tissue area with blood vessels in the n-slice chest CT image to obtain pulmonary blood vessels.

一种从胸部CT图像中提取肺血管的方法,其特征在于,包括如下步骤:A method for extracting pulmonary vessels from chest CT images, comprising the steps of:

第一步:利用CT图像三维特征平均投影密度结合多尺度圆点增强进行预处理;The first step: preprocessing by using the average projection density of CT image 3D features combined with multi-scale dot enhancement;

第二步:在所述指定图像层上选取肺部区域的指定像素点获得初始种子点,根据所述预设分割阈值以及初始种子点,在所述n层胸部CT图像进行3D区域增长,获得不带血管的肺组织区域;Step 2: select specified pixel points in the lung region on the specified image layer to obtain initial seed points, and perform 3D region growth on the n-layer chest CT images according to the preset segmentation threshold and initial seed points to obtain Areas of lung tissue without blood vessels;

第三步:在所述的肺组织区域进行形态学运算,获得带血管的封闭肺组织区域,计算血管阈值;Step 3: Perform morphological calculations on the lung tissue area to obtain a closed lung tissue area with blood vessels, and calculate the blood vessel threshold;

第四步:采用只对肺结节进行聚类的策略和快速准确自适应阈值两方面优化的DBSCAN超像素序列图像聚类算法,对超像素样本进行聚类,得到序列肺结节掩膜,最终得到肺部CT的序列肺结节图像;Step 4: Using the DBSCAN superpixel sequence image clustering algorithm optimized by the strategy of clustering only pulmonary nodules and the fast and accurate adaptive threshold, cluster the superpixel samples to obtain the sequential pulmonary nodule mask, Finally, the sequential lung nodule image of lung CT is obtained;

第五步:根据所述初始扩散面和血管阈值,在所述n层胸部CT图像的带血管的封闭肺组织区域内进行面扩散,获得肺血管。Step 5: According to the initial diffusion surface and the blood vessel threshold, surface diffusion is performed in the closed lung tissue area with blood vessels in the n-layer chest CT image to obtain pulmonary blood vessels.

以上所述仅为本发明的较佳实施例,并不用以限制本发明,凡在本发明的精神和原则之内,所作的任何修改、等同替换、改进等,均应包含在本发明的保护范围之内。The above descriptions are only preferred embodiments of the present invention, and are not intended to limit the present invention. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention shall be included in the protection of the present invention. within range.

Claims (2)

1.一种肺部CT图像的血管增强方法,其特征在于,包括如下步骤:1. a blood vessel enhancement method of lung CT image, is characterized in that, comprises the steps: 第一步:利用CT图像三维特征平均投影密度结合多尺度圆点增强进行预处理;The first step: preprocessing by using the average projection density of CT image 3D features combined with multi-scale dot enhancement; 第二步:在所述指定图像层上选取肺部区域的指定像素点获得初始种子点,根据所述预设分割阈值以及初始种子点,在所述n层胸部CT图像进行3D区域增长,获得不带血管的肺组织区域;Step 2: select specified pixel points in the lung region on the specified image layer to obtain initial seed points, and perform 3D region growth on the n-layer chest CT images according to the preset segmentation threshold and initial seed points to obtain Areas of lung tissue without blood vessels; 第三步:在所述的肺组织区域进行形态学运算,获得带血管的封闭肺组织区域,计算血管阈值;Step 3: Perform morphological calculations on the lung tissue area to obtain a closed lung tissue area with blood vessels, and calculate the blood vessel threshold; 第四步:采用只对肺结节进行聚类的策略和快速准确自适应阈值两方面优化的DBSCAN超像素序列图像聚类算法,对超像素样本进行聚类,得到序列肺结节掩膜,最终得到肺部CT的序列肺结节图像;Step 4: Using the DBSCAN superpixel sequence image clustering algorithm optimized by the strategy of clustering only pulmonary nodules and the fast and accurate adaptive threshold, cluster the superpixel samples to obtain the sequential pulmonary nodule mask, Finally, the sequential lung nodule image of lung CT is obtained; 第五步:根据所述初始扩散面和血管阈值,在所述n层胸部CT图像的带血管的封闭肺组织区域内进行面扩散,获得肺血管。Step 5: According to the initial diffusion surface and the blood vessel threshold, surface diffusion is performed in the closed lung tissue area with blood vessels in the n-layer chest CT image to obtain pulmonary blood vessels. 2.一种肺部CT图像的血管增强系统,其特征在于,包括:CT图像输入单元:用于接收输入CT图像;预设分割阈值获取单元:利用CT图像三维特征平均投影密度结合多尺度圆点增强进行预处理;不带血管的肺组织区域获取单元:用于在所述指定图像层上选取肺部区域的指定像素点获得初始种子点,根据所述预设分割阈值以及初始种子点,在所述n层胸部CT图像进行3D区域增长,获得不带血管的肺组织区域;血管阈值计算单元:在所述的肺组织区域进行形态学运算,获得带血管的封闭肺组织区域,计算血管阈值;初始扩散面获取单元:用于在所述指定图像层上的带血管的封闭肺组织区域查找大于血管阈值的像素点为初始标记点,获得初始扩散面;肺血管提取单元:用于根据所述初始扩散面和血管阈值,在所述n层胸部CT图像的带血管的封闭肺组织区域内进行面扩散,获得肺血管。2. A blood vessel enhancement system for lung CT images, characterized in that it includes: a CT image input unit: used to receive input CT images; a preset segmentation threshold acquisition unit: using the CT image three-dimensional feature average projection density combined with a multi-scale circle Point enhancement for preprocessing; lung tissue area acquisition unit without blood vessels: used to select specified pixel points of the lung area on the specified image layer to obtain initial seed points, according to the preset segmentation threshold and initial seed points, Perform 3D region growth on the n-layer chest CT image to obtain a lung tissue area without blood vessels; the blood vessel threshold calculation unit: perform morphological operations on the lung tissue area to obtain a closed lung tissue area with blood vessels, and calculate blood vessels Threshold; initial diffusion surface acquisition unit: used to find pixels larger than the blood vessel threshold in the closed lung tissue area with blood vessels on the specified image layer as the initial marker point, and obtain the initial diffusion surface; pulmonary blood vessel extraction unit: used to obtain the initial diffusion surface according to For the initial diffusion surface and the blood vessel threshold, surface diffusion is performed in the closed lung tissue area with blood vessels in the n-layer chest CT image to obtain pulmonary blood vessels.
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