CN119366857A - A LC resonant intraocular pressure monitoring sensor and its preparation method - Google Patents
A LC resonant intraocular pressure monitoring sensor and its preparation method Download PDFInfo
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- CN119366857A CN119366857A CN202411446408.1A CN202411446408A CN119366857A CN 119366857 A CN119366857 A CN 119366857A CN 202411446408 A CN202411446408 A CN 202411446408A CN 119366857 A CN119366857 A CN 119366857A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/16—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring intraocular pressure, e.g. tonometers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61G—TRANSPORT, PERSONAL CONVEYANCES, OR ACCOMMODATION SPECIALLY ADAPTED FOR PATIENTS OR DISABLED PERSONS; OPERATING TABLES OR CHAIRS; CHAIRS FOR DENTISTRY; FUNERAL DEVICES
- A61G5/00—Chairs or personal conveyances specially adapted for patients or disabled persons, e.g. wheelchairs
- A61G5/04—Chairs or personal conveyances specially adapted for patients or disabled persons, e.g. wheelchairs motor-driven
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61G—TRANSPORT, PERSONAL CONVEYANCES, OR ACCOMMODATION SPECIALLY ADAPTED FOR PATIENTS OR DISABLED PERSONS; OPERATING TABLES OR CHAIRS; CHAIRS FOR DENTISTRY; FUNERAL DEVICES
- A61G5/00—Chairs or personal conveyances specially adapted for patients or disabled persons, e.g. wheelchairs
- A61G5/10—Parts, details or accessories
- A61G5/1051—Arrangements for steering
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Abstract
The invention discloses an LC resonance intraocular pressure monitoring sensor and a preparation method thereof, and belongs to the technical field of flexible sensing. The preparation method comprises the steps of preparing a P (VDF-TrFE) film with a microstructure by using a reverse die method as a dielectric layer, then spraying MXene on the film by using a mask plate to prepare a patterned capacitor, preparing an inductance coil made of aluminum foil by using laser marking, and obtaining an MXene-based intraocular pressure sensor by using hot-pressing encapsulation; the preparation method disclosed by the invention uses MXene as an electrode material of the sensor, adopts a microstructure of the dielectric layer, has excellent sensitivity, is simple and has batch preparation feasibility.
Description
Technical Field
The invention relates to an LC resonance intraocular pressure monitoring sensor and a preparation method thereof, and belongs to the technical field of flexible sensing.
Background
Glaucoma is a second leading blinding disease worldwide and is also the first leading irreversible blinding disease worldwide. The statistics show that global glaucoma patients in 2020 are about 7600 ten thousand, chinese glaucoma patients are particularly prominent, about 2180 ten thousand, and about 567 ten thousand of blindmen are caused. Glaucoma is complicated in pathogenesis and has numerous causative factors, with ocular tension being the primary and the only known risk factor that can be altered. Intraocular pressure refers to the pressure of the eye contents against the inner wall of the eye and the interaction between the contents, and is normally in the range of 10-21mmHg, with glaucoma patients generally having high intraocular pressure. For glaucoma patients with abnormal intraocular pressure, intraocular pressure is monitored in early stage of disease, and intraocular pressure is reduced by timely medication or operation, so that damage to retinal nerves can be effectively slowed down, and blindness rate is effectively reduced.
Currently, tonometers are mainly used for measuring the intraocular pressure clinically, and common tonometers include a clamp tonometer, a applanation tonometer, a non-contact tonometer and the like, such as a Goldman tonometer, a Icare rebound tonometer and the like. The above means can only measure the instantaneous intraocular pressure value, and cannot accurately reflect the fluctuation condition of the intraocular pressure, so that the peak value of the intraocular pressure is easily missed, and the measurement is required under the guidance of doctors, so that misdiagnosis or missed diagnosis of glaucoma is easily caused. Therefore, a means for realizing 24-hour continuous intraocular pressure monitoring is needed in a safe and comfortable way with convenient operation.
With the development of MEMS technology and flexible electronic technology, more and more intraocular pressure sensors are widely used for 24-hour continuous intraocular pressure measurement, and are mainly classified into an implantable type and a contact lens type, and the contact lens type sensor can be further classified into an optical type, a resistive type and an LC (inductance capacitance) resonance type.
However, existing tonometric sensor technology has some outstanding problems:
1. The implanted intraocular pressure sensor needs to be implanted in an operation, can cause irreversible damage to an eye ball, has risks of intraocular liquid leakage and inflammation, has possibility of electric leakage, can influence daily life of a patient, and is not easy to accept by the patient.
2. The optical intraocular pressure sensor cannot monitor the intraocular pressure of a patient during sleeping at night, but the intraocular pressure generally reaches a peak at night, and the resistive intraocular pressure sensor is easily affected by external environment and is difficult to realize data transmission.
The preparation cost of the LC resonance intraocular pressure sensor is generally high, the preparation process is complex, and mass production is difficult to realize.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides a preparation method of an LC resonance intraocular pressure monitoring sensor.
The purpose of the invention is implemented by the following technical scheme:
the LC resonance type intraocular pressure monitoring sensor comprises a lower packaging layer 1, a capacitance lower polar plate 2, a dielectric layer 3, a capacitance upper polar plate 4, an inductance coil 5 and an upper packaging layer 6;
The capacitor lower polar plate 2, the dielectric layer 3, the capacitor upper polar plate 4 and the inductance coil 5 are positioned between the lower packaging layer 1 and the upper packaging layer 6;
The upper electrode plate 4 of the capacitor is a circular ring, the outer end face of the circular ring is uniformly provided with protruding structures, the number of the protruding structures is 6-9, and the protruding structures are semicircular, petal-shaped, triangular and trapezoidal;
The inductance coil 5 is positioned in the circular ring of the capacitor upper polar plate 4, and one end of the inductance coil 5 is connected with the circular ring of the capacitor upper polar plate 4 through silver paste;
The number of turns of the inductance coil 5 is 3-4, the width of each turn is 200-300 mu m, and the interval between each turn is 200-300 mu m;
the shape and the size of the capacitor lower polar plate 2 are consistent with those of the capacitor upper polar plate 4;
The capacitor lower polar plate 2 and the capacitor upper polar plate 4 are made of MXene materials;
The circular ring of the capacitor lower polar plate 2 is connected with the other end of the inductance coil 5 through silver paste;
The dielectric layer 3 is a circular ring, grooves are uniformly distributed on the surface of the circular ring, the diameter of each groove is 2.5-3 mu m, the depth of each groove is 1.2-1.5 mu m, and the distance between the grooves is 3-4 mu m;
the medium layer 3 is made of P (VDF-TrFE);
the inner diameter of the circular ring of the dielectric layer 3 is consistent with the inner diameter of the circular ring of the capacitor upper polar plate 4, the outer diameter of the circular ring of the dielectric layer 3 is d, and the distance from the top end of the protruding structure on the outer end surface of the circular ring of the capacitor upper polar plate 4 to the center point of the circular ring of the capacitor upper polar plate 4 is d;
the dielectric layer 3 is positioned between the capacitor lower polar plate 2 and the capacitor upper polar plate 4;
the lower packaging layer 1 and the upper packaging layer 6 are PDMS circular plates.
A method for manufacturing an LC resonant intraocular pressure monitoring sensor, the method comprising the steps of:
Firstly, preparing a dielectric film by using a reverse die method, and then performing plasma treatment on the dielectric film to improve the surface hydrophilicity of the dielectric film so as to enable the combination of MXene and the film to be more compact;
Secondly, spraying an MXene material on one surface of the dielectric film subjected to plasma treatment by using a PET mask plate to obtain a capacitor lower polar plate 2, and finally spraying an MXene material on the other surface of the dielectric film to obtain a capacitor upper polar plate 4;
thirdly, marking aluminum foil by laser to obtain an inductance coil 5;
Fourthly, placing the inductance coil 5 obtained in the third step into the circular ring of the upper electrode plate 4 of the capacitor, connecting one end of the inductance coil 5 with the circular ring of the upper electrode plate 4 of the capacitor through silver paste, and connecting the other end of the inductance coil 5 with the circular ring of the lower electrode plate 2 of the capacitor through silver paste to obtain an assembly;
Fifthly, packaging the assembly obtained in the fourth step through a lower packaging layer 1 and an upper packaging layer 6;
and sixthly, carrying out hot press molding on the device packaged in the fifth step, wherein the hot press molding temperature is 150-160 ℃, and the hot press molding time is 20-30min, so as to obtain the LC resonance intraocular pressure monitoring sensor.
In the first step, preparing a medium film by using a DMF solution of 20% of P (VDF-TrFE) by mass fraction, wherein the temperature for preparing the medium film is 80-90 ℃, the heating time is 3-6min, the template material adopted in the preparation of the medium film is sapphire, the surface of the sapphire is provided with a layer of microsphere structure matched with a groove, and the rotating speed for preparing the medium film is 1500rpm for 20s;
in the second step, the spraying temperature is 60-70 ℃ and the spraying distance is 25-30cm;
in the second step, the concentration of the MXene material is 2mg/mL, and the dosage is 500 mu L;
In the fifth step, polydimethylsiloxane (PDMS) is used for packaging, the mass ratio of the Polydimethylsiloxane (PDMS) to the curing agent is 1:10, the Polydimethylsiloxane (PDMS) and the curing agent are mixed and then stand for 4 hours to remove bubbles, and then the mixture is cured for 20-30 minutes at 90-100 ℃;
and in the sixth step, the packaged device is taken down from the glass sheet and placed in a copper metal mold for hot press molding.
The LC resonance type intraocular pressure monitoring sensor is applied to an intelligent electric wheelchair, and the intelligent electric wheelchair is controlled by signal transmission through intelligent glasses;
The intelligent electric wheelchair comprises a seat, wheels, a communication module, a signal processing module and a driving module;
the communication module is used for receiving signals of whether consciousness blinks output by the microprocessor and outputting the received signals of whether consciousness blinks to the signal processing module;
The signal processing module is used for receiving the signals of whether consciousness blinks output by the communication module, converting the received signals of whether consciousness blinks into driving instructions and outputting the driving instructions to the driving module;
the driving module is used for receiving the driving instruction output by the signal processing module and controlling the movement of the wheels according to the received driving instruction;
the intelligent glasses comprise a glasses frame, lenses and glasses legs, wherein a reading coil is arranged on the lenses, the reading coil is integrated on the lenses through a photoetching process, the reading coil is made of gold or copper, the inner diameter is 8-10mm, the outer diameter is 14-16mm, the number of turns is 5-7, and the vision of a patient is not affected;
The glasses leg is provided with a microprocessor, the microprocessor is electrically connected with the reading coil, the microprocessor is used for acquiring the reflection coefficient S 11 of the reading coil, acquiring the resonance frequency of the sensor circuit according to the acquired reflection coefficient S 11, acquiring the intraocular pressure of a wearer according to the resonance frequency, judging whether the wearer consciously blinks according to the intraocular pressure of the wearer, and outputting a consciously blinked signal to the communication module;
The method for controlling the intelligent electric wheelchair through signal transmission of the intelligent glasses comprises the following steps:
Step 1, a patient wears an LC resonance intraocular pressure sensor on a cornea and wears intelligent glasses, and different conscious blink behaviors are generated according to actual road conditions;
Step 2, the microprocessor acquires the reflection coefficient S 11 of the reading coil, acquires the resonance frequency of the sensor circuit according to the acquired reflection coefficient S 11, acquires the intraocular pressure of the wearer according to the resonance frequency, judges whether the wearer blinks consciously according to the intraocular pressure of the wearer, and outputs a consciously blinked signal to the communication module;
Step 3, the communication module outputs the received signals of conscious blink to the signal processing module;
Step 4, the signal processing module converts the received signals of conscious blink into driving instructions and outputs the driving instructions to the driving module;
and 5, the driving module controls the movement of the wheels according to the received driving instruction.
In the step 3, the basis for judging whether the wearer consciously blinks according to the intraocular pressure of the wearer is as follows:
when the intraocular pressure value is greater than or equal to 25mmHg and the duration is higher than the threshold value, judging that the wearer generates conscious blinking behavior or eye closure;
when the intraocular pressure value is greater than or equal to 25mmHg and the duration is lower than the threshold value, judging that the wearer generates unconscious blinking behavior;
When the intraocular pressure value is less than 25mmHg, no blink behavior exists;
In the case of conscious blinks, the relationship between the number of blinks and the acceleration, deceleration, left turn, right turn, and stop of the wheelchair can be set.
The invention has the following advantages:
1. The preparation method disclosed by the invention uses MXene as an electrode material of the sensor, and the sensor has an extremely wide measurement range due to the good conductivity and mechanical properties of the MXene.
2. The preparation method disclosed by the invention utilizes the reverse die method to prepare the P (VDF-TrFE) medium film with the microstructure, thereby improving the test sensitivity of the sensor.
3. The preparation method disclosed by the invention adopts reasonable structural design, and the MXene has good light transmittance, can not block the visual field of a patient, and the packaged sensor is very thin, has good flexibility and is comfortable to wear.
4. The preparation method disclosed by the invention has the advantages of simple flow, low cost and short period.
The invention discloses an LC (inductance capacitance) resonant intraocular pressure monitoring sensor and a preparation method thereof, and belongs to the technical field of flexible sensing. The preparation method comprises the steps of preparing a P (VDF-TrFE) film with a microstructure by using a reverse die method as a dielectric layer, then spraying MXene on the film by using a mask plate to prepare a patterned capacitor, preparing an inductance coil made of aluminum foil by using laser marking, and obtaining an MXene-based intraocular pressure sensor by using hot-pressing encapsulation; the preparation method disclosed by the invention uses MXene as an electrode material of the sensor, adopts a microstructure of the dielectric layer, has excellent sensitivity, is simple and has batch preparation feasibility.
Drawings
FIG. 1 is a schematic diagram of an LC resonant intraocular pressure sensor;
FIG. 2 is a schematic view of an outer end face and surface;
FIG. 3 is a diagram of the capacitance of an LC resonant intraocular pressure sensor;
Fig. 4 is a capacitance-intraocular pressure test chart of an LC resonance type intraocular pressure sensor in which pressure is increased/decreased in steps of 9 mmHg;
fig. 5 is a frequency-intraocular pressure test chart of an LC resonance type intraocular pressure sensor in which the pressure is increased in steps of 10 mmHg.
Detailed Description
The invention will be further described with reference to the accompanying drawings and examples, the scope of the invention not being limited to the following:
Example 1
As shown in fig. 1 and 2, an LC resonant intraocular pressure monitoring sensor includes a lower packaging layer 1, a capacitor lower electrode plate 2, a dielectric layer 3, a capacitor upper electrode plate 4, an inductance coil 5, and an upper packaging layer 6;
The capacitor lower polar plate 2, the dielectric layer 3, the capacitor upper polar plate 4 and the inductance coil 5 are positioned between the lower packaging layer 1 and the upper packaging layer 6;
The upper electrode plate 4 of the capacitor is a circular ring, the outer end face of the circular ring is uniformly provided with protruding structures, the number of the protruding structures is 6-9, and the protruding structures are semicircular, petal-shaped, triangular and trapezoidal;
The inductance coil 5 is positioned in the circular ring of the capacitor upper polar plate 4, and one end of the inductance coil 5 is connected with the circular ring of the capacitor upper polar plate 4 through silver paste;
The number of turns of the inductance coil 5 is 3-4, the width of each turn is 200-300 mu m, and the interval between each turn is 200-300 mu m;
the shape and the size of the capacitor lower polar plate 2 are consistent with those of the capacitor upper polar plate 4;
The capacitor lower polar plate 2 and the capacitor upper polar plate 4 are made of MXene materials;
The circular ring of the capacitor lower polar plate 2 is connected with the other end of the inductance coil 5 through silver paste;
The dielectric layer 3 is a circular ring, grooves are uniformly distributed on the surface of the circular ring, the diameter of each groove is 2.5-3 mu m, the depth of each groove is 1.2-1.5 mu m, and the distance between the grooves is 3-4 mu m;
the medium layer 3 is made of P (VDF-TrFE);
the inner diameter of the circular ring of the dielectric layer 3 is consistent with the inner diameter of the circular ring of the capacitor upper polar plate 4, the outer diameter of the circular ring of the dielectric layer 3 is d, and the distance from the top end of the protruding structure on the outer end surface of the circular ring of the capacitor upper polar plate 4 to the center point of the circular ring of the capacitor upper polar plate 4 is d;
the dielectric layer 3 is positioned between the capacitor lower polar plate 2 and the capacitor upper polar plate 4;
the lower packaging layer 1 and the upper packaging layer 6 are PDMS circular plates.
A method for manufacturing an LC resonant intraocular pressure monitoring sensor, the method comprising the steps of:
(1) Preparation of dielectric film
First, a 20% by mass solution of P (VDF-TrFE) was prepared, and DMF was used as a solvent. A layer of P (VDF-TrFE) solution is uniformly spin-coated on the surface of a template (the template material adopted by the reverse mould is sapphire, the surface of the template is provided with a layer of microsphere structure with the diameter of 2.7 mu m and the height of 1.5 mu m), the rotation speed and the time adopted during the coating are respectively 1500rpm and 20s, and then the template is heated for 5min at 90 ℃. The P (VDF-TrFE) medium film with the surface microstructure is obtained after the water is added and torn off due to the hydrophobicity of the P (VDF-TrFE);
(2) Preparation of LC resonance intraocular pressure sensor
500. Mu.L of a 2mg/mL aqueous solution of Ti 3C2Tx -MXene was prepared and added to a spray gun, a P (VDF-TrFE) dielectric film was fixed on a mold, a PET mask was aligned with the film, and the film was treated in a plasma surface treatment machine for 10 minutes to improve the hydrophilicity of the P (VDF-TrFE) dielectric film. The Ti 3C2Tx -MXene material was then sprayed at 65℃to give the capacitor plate 2 and capacitor plate 4 of FIG. 1. Fig. 3 shows a representation of sensor capacitance entities of different shapes prepared separately. The inductor coil is then marked on the aluminum foil using a laser marking technique, as shown at 5 in fig. 1. And connecting the electrode pins with the pins of the inductance coil by using conductive silver paste to form a complete LC circuit.
The prepared device was encapsulated with Polydimethylsiloxane (PDMS) and cured at 90 ℃ for 20min. The packaged device was then thermoformed using a custom-made metal mold and heated at 160 ℃ for 30 minutes to obtain an LC resonant intraocular pressure sensor that could be practically worn in the eye.
Performance test:
The molded intraocular pressure sensor is fixed on an eyeball mould, and the height of the liquid level is controlled through a stepping motor, so that the pressure value in the mould is controlled. The capacitance is measured by using an LCR tester, the tester is connected with two electrodes of the capacitance, the control pressure is increased by taking 9mmHg as a step length, the measured capacitance-intraocular pressure data is shown in figure 4, and according to figure 4, when the intraocular pressure is changed in a step-like manner, the capacitance is also changed in a step-like manner along with the intraocular pressure value, so that the sensor sensitive capacitance can accurately reflect the change of the intraocular pressure;
The self-made single-turn blister copper coil is used as an external reading coil, the self-made single-turn blister copper coil is connected to a portable vector network analyzer, the distance between the reading coil and a sensor is within 1cm, the resonant frequency of an LC loop of the sensor is read, the control pressure is increased by taking 10mmHg as a step length, the measurement result is shown in fig. 5, the range of 0-40mmHg is shown according to fig. 5, the resonant frequency of a sensor circuit is gradually reduced along with the gradual increase of the intraocular pressure, and the fact that the resonant frequency of the sensor can accurately reflect the change of the intraocular pressure is shown.
An application of an LC resonance intraocular pressure monitoring sensor is provided, when conscious blinks are adopted, blinks 1 time in 4s represent left rotation, blinks 2 times represent right rotation, blinks 3 times represent acceleration, blinks 4 times represent deceleration, an eye normally closed representation system is closed, and a duration threshold is 500ms;
The method comprises the following steps:
Step 1, a patient wears an LC resonance intraocular pressure sensor on a cornea and wears intelligent glasses, and different conscious blink behaviors are generated according to actual road conditions;
Step 2, the microprocessor acquires the reflection coefficient S 11 of the reading coil, acquires the resonant frequency of the sensor circuit according to the acquired reflection coefficient S 11, acquires the intraocular pressure of the wearer to be 30mmHg according to the resonant frequency, and judges that the wearer blinks consciously, only one consciously blinks within 4S, and outputs a consciously blinked signal to the communication module;
Step 3, the communication module outputs the received conscious blink signal to the signal processing module;
Step 4, the signal processing module converts the received conscious blink signal into a driving instruction and outputs the driving instruction to the driving module;
and 5, the driving module controls the wheels to turn left according to the received driving instruction.
Example 2
An application of an LC resonance intraocular pressure monitoring sensor comprises the following steps:
Step 1, a patient wears an LC resonance intraocular pressure sensor on a cornea and wears intelligent glasses, and different conscious blink behaviors are generated according to actual road conditions;
step 2, the microprocessor acquires the reflection coefficient S 11 of the reading coil, acquires the resonance frequency of the sensor circuit according to the acquired reflection coefficient S 11, acquires the intraocular pressure of the wearer as 30mmHg according to the resonance frequency, and judges that the wearer unconsciously blinks with the duration of 200ms, and outputs a signal of the unconscious blink to the communication module;
Step 3, the communication module outputs the received conscious blink signal to the signal processing module;
Step 4, the signal processing module converts the received conscious blink signal into a driving instruction and outputs the driving instruction to the driving module;
and 5, the driving module controls the continuous previous behavior of the wheels according to the received driving instruction.
The foregoing is only a preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art who is skilled in the art to which the present invention pertains will appreciate that the technical scheme and the inventive concept according to the present invention are equally substituted or changed within the scope of the present invention.
Claims (10)
1. An LC resonant intraocular pressure monitoring sensor, characterized in that:
the LC resonance type intraocular pressure monitoring sensor comprises a lower packaging layer, a capacitor lower polar plate, a dielectric layer, a capacitor upper polar plate, an inductance coil and an upper packaging layer;
The capacitor lower polar plate, the dielectric layer, the capacitor upper polar plate and the inductance coil are positioned between the lower packaging layer and the upper packaging layer;
the upper polar plate of the capacitor is a circular ring, and convex structures are uniformly distributed on the outer end surface of the circular ring;
The inductance coil is positioned in the circular ring of the upper electrode plate of the capacitor, and one end of the inductance coil is connected with the circular ring of the upper electrode plate of the capacitor through silver paste;
The lower polar plate of the capacitor and the capacitor the shape and the size of the upper polar plate are consistent;
The circular ring of the lower polar plate of the capacitor is connected with the other end of the inductance coil through silver paste;
the dielectric layer is a circular ring, and grooves are uniformly distributed on the surface of the circular ring;
The outer diameter of the circular ring of the dielectric layer is d, and the distance from the top end of the protruding structure on the outer end surface of the circular ring of the upper polar plate of the capacitor to the center point of the circular ring of the upper polar plate of the capacitor is d;
the dielectric layer is positioned between the capacitor lower polar plate and the capacitor upper polar plate.
2. An LC resonant intraocular pressure monitoring sensor according to claim 1, characterized in that:
The number of the protruding structures of the upper polar plate of the capacitor is 6-9, and the protruding structures are semicircular, petal-shaped, triangular or trapezoid.
3. An LC resonant intraocular pressure monitoring sensor according to claim 1, characterized in that:
The number of turns of the inductance coil is 3-4 turns, the width of each turn is 200-300 mu m, and the interval between each turn is 200-300 mu m.
4. An LC resonant intraocular pressure monitoring sensor according to claim 1, characterized in that:
the lower electrode plate and the upper electrode plate of the capacitor are made of MXene materials.
5. An LC resonant intraocular pressure monitoring sensor according to claim 1, characterized in that:
the diameter of the grooves of the dielectric layer is 2.5-3 mu m, the depth of the grooves is 1.2-1.5 mu m, and the distance between the grooves is 3-4 mu m.
6. An LC resonant intraocular pressure monitoring sensor according to claim 1, characterized in that:
the medium layer is made of P (VDF-TrFE);
The lower packaging layer and the upper packaging layer are PDMS circular plates.
7. The preparation method of the LC resonance intraocular pressure monitoring sensor is characterized by comprising the following steps of:
firstly, preparing a dielectric film by using a reverse molding method, and then performing plasma treatment on the dielectric film;
secondly, spraying an MXene material on one surface of the dielectric film subjected to plasma treatment by using a PET mask plate to obtain a lower electrode plate of the capacitor, and finally spraying an MXene material on the other surface of the dielectric film to obtain an upper electrode plate of the capacitor;
Thirdly, marking aluminum foil by laser to obtain an inductance coil;
Fourthly, placing the inductance coil obtained in the third step into a circular ring of an upper polar plate of the capacitor, connecting one end of the inductance coil with the circular ring of the upper polar plate of the capacitor through silver paste, and connecting the other end of the inductance coil with the circular ring of a lower polar plate of the capacitor through silver paste to obtain an assembly;
Fifthly, packaging the assembly obtained in the fourth step through a lower packaging layer and an upper packaging layer;
and sixthly, carrying out hot press molding on the device packaged in the fifth step, wherein the hot press molding temperature is 150-160 ℃, and the hot press molding time is 20-30min, so as to obtain the LC resonance intraocular pressure monitoring sensor.
8. The method for manufacturing an LC resonant intraocular pressure monitoring sensor according to claim 7, wherein:
in the first step, a DMF solution with the mass fraction of 20% of P (VDF-TrFE) is used for preparing a medium film, the temperature for preparing the medium film is 80-90 ℃, the heating time is 3-6min, the template material adopted in the preparation of the medium film is sapphire, the surface of the sapphire is provided with a layer of microsphere structure matched with a groove, and the rotating speed for preparing the medium film is 1500rpm and the time is 20s.
9. The method for manufacturing an LC resonant intraocular pressure monitoring sensor according to claim 7, wherein:
in the second step, the spraying temperature is 60-70 ℃ and the spraying distance is 25-30cm;
In the second step, the concentration of the MXene material is 2mg/mL, and the dosage is 500 mu L.
10. The method for manufacturing an LC resonant intraocular pressure monitoring sensor according to claim 7, wherein:
In the fifth step, polydimethylsiloxane is used for packaging, the mass ratio of the polydimethylsiloxane to the curing agent is 1:10, the polydimethylsiloxane and the curing agent are mixed and then stand for 4 hours to remove bubbles, and then the mixture is cured for 20-30 minutes at the temperature of 90-100 ℃;
and in the sixth step, the packaged device is taken down from the glass sheet and placed in a copper metal mold for hot press molding.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN120760895A (en) * | 2025-09-05 | 2025-10-10 | 北京航空航天大学 | An LC sensor and smart invisible braces for monitoring human physiological signals |
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| CN118047347A (en) * | 2024-02-28 | 2024-05-17 | 北京理工大学 | A method for preparing a flexible curved surface intraocular pressure monitoring sensor |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US20140296688A1 (en) * | 2011-06-06 | 2014-10-02 | The Hong Kong University Of Science And Technology | Surface deformation sensor |
| CN118047347A (en) * | 2024-02-28 | 2024-05-17 | 北京理工大学 | A method for preparing a flexible curved surface intraocular pressure monitoring sensor |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN120760895A (en) * | 2025-09-05 | 2025-10-10 | 北京航空航天大学 | An LC sensor and smart invisible braces for monitoring human physiological signals |
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