CN1183950C - Chinese herbal medicine preparation for treating burns - Google Patents
Chinese herbal medicine preparation for treating burns Download PDFInfo
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- CN1183950C CN1183950C CN 03111500 CN03111500A CN1183950C CN 1183950 C CN1183950 C CN 1183950C CN 03111500 CN03111500 CN 03111500 CN 03111500 A CN03111500 A CN 03111500A CN 1183950 C CN1183950 C CN 1183950C
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- medicine preparation
- fine powders
- chinese medicine
- pulverized
- meshes
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- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- 241000411851 herbal medicine Species 0.000 title description 2
- 239000003814 drug Substances 0.000 claims abstract description 35
- 229940079593 drug Drugs 0.000 claims abstract description 14
- 239000004863 Frankincense Substances 0.000 claims abstract description 12
- 239000002674 ointment Substances 0.000 claims abstract description 5
- 239000007921 spray Substances 0.000 claims abstract description 5
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 claims description 11
- 241000717739 Boswellia sacra Species 0.000 claims description 10
- 241000217407 Margaritifera Species 0.000 claims description 10
- 241001057584 Myrrha Species 0.000 claims description 10
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 7
- 235000005956 Cosmos caudatus Nutrition 0.000 claims description 7
- 244000293323 Cosmos caudatus Species 0.000 claims description 7
- MYSWGUAQZAJSOK-UHFFFAOYSA-N ciprofloxacin Chemical compound C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 MYSWGUAQZAJSOK-UHFFFAOYSA-N 0.000 claims description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- 239000000843 powder Substances 0.000 abstract description 13
- 230000000694 effects Effects 0.000 abstract description 11
- 230000001737 promoting effect Effects 0.000 abstract description 9
- 206010053615 Thermal burn Diseases 0.000 abstract description 8
- 239000008280 blood Substances 0.000 abstract description 8
- 210000004369 blood Anatomy 0.000 abstract description 8
- 238000005469 granulation Methods 0.000 abstract description 7
- 230000003179 granulation Effects 0.000 abstract description 7
- 230000003213 activating effect Effects 0.000 abstract description 4
- 230000017531 blood circulation Effects 0.000 abstract description 3
- 230000008961 swelling Effects 0.000 abstract description 3
- 229940099259 vaseline Drugs 0.000 abstract description 3
- 208000025865 Ulcer Diseases 0.000 abstract description 2
- 231100000397 ulcer Toxicity 0.000 abstract description 2
- 235000003717 Boswellia sacra Nutrition 0.000 abstract 2
- 240000007551 Boswellia serrata Species 0.000 abstract 2
- 235000012035 Boswellia serrata Nutrition 0.000 abstract 2
- 240000007311 Commiphora myrrha Species 0.000 abstract 2
- 235000006965 Commiphora myrrha Nutrition 0.000 abstract 2
- 235000007265 Myrrhis odorata Nutrition 0.000 abstract 2
- 229940105847 calamine Drugs 0.000 abstract 2
- 229910052602 gypsum Inorganic materials 0.000 abstract 2
- 239000010440 gypsum Substances 0.000 abstract 2
- 229910052864 hemimorphite Inorganic materials 0.000 abstract 2
- 235000014692 zinc oxide Nutrition 0.000 abstract 2
- 239000011787 zinc oxide Substances 0.000 abstract 2
- CPYIZQLXMGRKSW-UHFFFAOYSA-N zinc;iron(3+);oxygen(2-) Chemical compound [O-2].[O-2].[O-2].[O-2].[Fe+3].[Fe+3].[Zn+2] CPYIZQLXMGRKSW-UHFFFAOYSA-N 0.000 abstract 2
- 229910021532 Calcite Inorganic materials 0.000 abstract 1
- 208000009043 Chemical Burns Diseases 0.000 abstract 1
- 208000013935 Electric injury Diseases 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 206010040943 Skin Ulcer Diseases 0.000 description 7
- 231100000019 skin ulcer Toxicity 0.000 description 7
- 231100000614 poison Toxicity 0.000 description 6
- 239000003440 toxic substance Substances 0.000 description 6
- 230000029663 wound healing Effects 0.000 description 6
- 230000035876 healing Effects 0.000 description 5
- 206010052428 Wound Diseases 0.000 description 4
- 208000027418 Wounds and injury Diseases 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 230000002265 prevention Effects 0.000 description 4
- 210000001519 tissue Anatomy 0.000 description 4
- 206010060891 General symptom Diseases 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000003053 toxin Substances 0.000 description 3
- 230000000472 traumatic effect Effects 0.000 description 3
- 241000721047 Danaus plexippus Species 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 230000000202 analgesic effect Effects 0.000 description 2
- 230000008034 disappearance Effects 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000009416 jing wan hong Substances 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 230000001338 necrotic effect Effects 0.000 description 2
- 231100000241 scar Toxicity 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 230000017423 tissue regeneration Effects 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- 206010002198 Anaphylactic reaction Diseases 0.000 description 1
- 208000003656 Electric Burns Diseases 0.000 description 1
- 206010063560 Excessive granulation tissue Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 208000001431 Psychomotor Agitation Diseases 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 230000036783 anaphylactic response Effects 0.000 description 1
- 208000003455 anaphylaxis Diseases 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000001804 debridement Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 230000003628 erosive effect Effects 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 210000001126 granulation tissue Anatomy 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000014860 sensory perception of taste Effects 0.000 description 1
- 206010040872 skin infection Diseases 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000011477 surgical intervention Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
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- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention discloses a Chinese medicine preparation for treating burns, which is proportionally composed of gypsum, calamine, calcite, ophicslcite, cuttlebone, myrrh, frankincense, pearl and nacre, wherein the gypsum, the calamine and the nacre are respectively calcined, and then are pulverized into fine powders of 100 to 200 meshes to be used, and the myrrh and the frankincense are respectively stir-fried and pulverized into fine powders of 100 to 200 meshes to be used; according to the formula, the other medicines are pulverized into fine powder of 100 to 200 meshes, and all the fine powders are uniformly mixed by adding Vaseline so as to be prepared into an ointment. The preparation can also be made into sprays or aqueous preparations in pharmacy. The Chinese medicine preparation has the curative effects of clearing heat, removing toxicity, activating blood circulation to dissipate blood stasis, reducing swelling, stopping pain, eliminating slough and promoting granulation so as to be used for treating burns, scalds, electric injury, chemical burns caused by high temperature and various surgical sores and ulcers.
Description
Technical field:
The invention provides a kind of Chinese medicine preparation for the treatment of burn, belong to the pharmaceutical technology field of Chinese traditional treatment burn and scald disease.
Background technology:
At present, the medicine of existing multiple treatment burn and scald on the market, as: JINGWANHONG RUANGAO etc., but antiinflammatory, healing and analgesic effect for burn wound are not desirable especially, and some can also cause whole body or local anaphylaxis, and be difficult to the prevention and the control ratio of traumatic infection, large-area slightly degree of depth wound surface need be made skin graft and can be healed, cicatrization after the healing is more, and in therapeutic process coating repeatedly, patient is painful big.
Summary of the invention:
The invention provides a kind of Chinese medicine preparation for the treatment of burn, have and relieve the pain rapidly, wound healing is fast, and characteristics such as preventing from scar have overcome the shortcoming of existing treatment burn and scald medicine.
Technical solution of the present invention is as follows: according to the basic principle of China's Chinese medicine treatment burn and scald, with reference to the modern pharmacological research achievement, from motherland's medicine treasure-house, filter out and have hemostasis and anti-inflammation, evacuation of pus is pulled out dried, the closing in granulation promoting, the pure Chinese herb medicine of heat-clearing and toxic substances removing is made externally used paste through the conventional medicament processing procedure.
Medicine of the present invention is made by following raw materials by weight portion:
Gypsum Fibrosum 30～45, Calamina 30～45, Calcitum rubrum 20～35, Ophicalcitum 28～35, Endoconcha Sepiae 10～18, Myrrha 6～10, Olibanum 4～8, Margarita 1～3, Concha Margaritifera 3～6.
Optimum ratio of the present invention is:
Gypsum Fibrosum Preparatum 35, Calamina (calcined and quenched) 35, Calcitum rubrum 28, Ophicalcitum 32, Endoconcha Sepiae 13, Myrrha (parched) 9, Olibanum (parched) 5, Margarita 1.5, calcined Concha Margaritifera 4.3.
Processing procedure is as follows:
It is stand-by that Gypsum Fibrosum, Calamina and Concha Margaritifera are ground into 100～200 order fine powders behind the calcine respectively; It is stand-by that Myrrha, Olibanum are ground into 100～200 order fine powders after the parch respectively; By above-mentioned prescription other medicines are ground into 100～200 order fine powders, the mix homogeneously of all putting together, and adding vaseline is modulated into ointment.
Above-mentioned medicament can also be made said spray of pharmaceutics or water preparation.
Indication: clearing away heat to alleviate pain, blood activating and promoting tissue regeneration.Be used for area and be no more than 10% shallow, dark II ° of burn.Comprise that scald, electric burn, high temeperature chemistry product burn.Various boils.
Using method: wound surface is cleaned with physiological saline solution, after the debridement, medicine evenly is applied on the sterile gauze, and the about 1～2mm of thickness of covering spreads on wound surface, and wrapping is fixing, and the next day changes dressings once.
The present invention is the secret recipe of treatment burn handed down from one's ancestors, is basic the guidance with the theory of Chinese medical science, and the clinical experience in conjunction with for many years forms through choosing.Wherein,
Gypsum Fibrosum, Calamina are monarch drug, the Gypsum Fibrosum acrid-sweet flavor, and property Great Cold, can clearing away heat-fire, external application can be held back skin ulcer by removing dampness, is the key medicine of treatment burn.The Calamina sense of taste is flat, also is the surgical intervention skin infection, can detoxify and have the effect of removing dampness erosion prevention and muscle growing, and two medicines match and can strengthen heat-clearing and toxic substances removing, and removing dampness is held back the effect of skin ulcer.The ministerial drug Calcitum rubrum: acrid in the mouth is salty, and is cold in nature, the energy resolving heat and reducing pathogenic fire, and relieving restlessness is quenched the thirst; Ophicalcitum: sour-acrid taste, property is flat, sour and astringent convergence, Xin Nenghang looses, but the removing stasis to stop bleeding pain, auxiliary monarch drug, heat-clearing and toxic substances removing, removing dampness are held back skin ulcer blood stasis dispersing and deswelling pain relieving granulation promoting.Adjuvant drug Endoconcha Sepiae salty in the mouth, puckery, property are little wet, and external has the dampness hemostasia and promoting granulation to hold back the merit of skin ulcer; The little toil of Olibanum, property is wet, merit be apt to activating blood circulation to dissipate blood stasis, stagnation resolvation blood and then pain only, the muscle life; Myrrha, but eliminating stasis to stop pain detumescence and promoting granulation, three medicines match, and have the effect of dissipating blood stasis for subsidence of swelling pain relieving removing the necrotic tissue and promoting granulation.Margarita, sweet in the mouth, salty, cold in nature, the energy heat-clearing and toxic substances removing, promoting tissue regeneration and ulcer healing is joined Concha Margaritifera, but potentiation.Two medicines share, and can strengthen heat-clearing and toxic substances removing, hold back the effect of creation flesh.More than each medicine mutually 5, play the therapeutic effect of heat-clearing and toxic substances removing, activating blood circulation to dissipate blood stasis, reducing swelling and alleviating pain, removing the necrotic tissue and promoting granulation altogether.
Good effect of the present invention is: preparation is that pure Chinese herbal medicine is made, and toxic and side effects is little, and treating both the principal and secondary aspects of a disease is evident in efficacy, and clinical symptom disappearance is rapid.
For showing the therapeutic effect of medicine of the present invention, selected 132 routine burn and scald patients use medicine of the present invention to treat, and carry out statistical analysis through system's clinical observation and are summarized as follows:
One, diagnostic criteria:
1, area calculates: Chinese rule of Nine, palm test.
2, depth estimation: three degree quarterings.
3, state of an illness classification:
Minor burn: the gross area is burnt at the II below 9%.
Moderate burn: the gross area is 10～29%, or the III burn surface area is below 10%.
4, Chinese medical discrimination: the flourishing card of fire-toxin, fire-toxin impairment of YIN card, fire-toxin inside fire attack internal organs, syndrome of yin deficiency involving yang, deficiency of both QI and blood, the cloudy stomach that decreases loses card.
Two, curative effect judging standard:
1, clinical cure: wound healing, General Symptoms disappears.
2, produce effects: II skin ulcer face, total wound healing are 90% or more or III skin ulcer face, and the gross area heals more than 50%, the General Symptoms disappearance.
3, effective: II ° of skin ulcer face, total wound healing 50% above III ° total wound healing is more than 30%, and General Symptoms disappears.
4, invalid: do not reach effective standard, traumatic infection fails to control.
Three, curative effect:
| Grouping | The example number | 14 days healing rates (%) | Healing time (my god) | The VAS scoring | ||
| 1 day | 5 days | 11 days | ||||
| The present invention | 76 | 77.04±12.59 | 16.64+2.48 | 3.95±2.48 | 1.99±1.80 | 0.70±0.80 |
| JINGWANHONG | 56 | 59.55±12.59 | 20.29±2.37 | 3.97±2.85 | 2.88±2.50 | 1.08±1.08 |
| The P value | ＜0.001 | ＜0.001 | ＞0.05 | ＞0.05 | ＞0.05 | |
Sum up:
The present invention is in treatment burn and scald patient's process; brought into play obviously analgesic effect fast; the prevention of highly significant and control traumatic infection; the speed of molten crust decrustation is fast; the parabiosis tissue there is good protective action; can promote the growth of granulation tissue and epithelial tissue, prevention and minimizing wound healing scar tissue form, and have obtained curative effect preferably.
The specific embodiment:
Embodiment 1
Take by weighing Gypsum Fibrosum 35g, Calamina 35g, Calcitum rubrum 28g, Ophicalcitum 32g, Endoconcha Sepiae 14g, Myrrha 9g, Olibanum 5g, Margarita 1.8g, Concha Margaritifera 4.5g.
It is stand-by that Gypsum Fibrosum, Calamina and Concha Margaritifera are ground into 100～200 order fine powders behind the calcine respectively; It is stand-by that Myrrha, Olibanum are ground into 100～200 order fine powders after the parch respectively; By above-mentioned prescription other medicines are ground into 100～200 order fine powders, the mix homogeneously of all putting together, and adding vaseline is modulated into ointment.Other project should meet 2000 editions ointment projects of Pharmacopoeia of People's Republic of China relevant requirements.
Embodiment 2
Take by weighing Gypsum Fibrosum 45g, Calamina 35g, Calcitum rubrum 25g, Ophicalcitum 40g, Endoconcha Sepiae 12g, Myrrha 13g, Olibanum 4g, Margarita 1.8g, Concha Margaritifera 6g.
It is stand-by that Gypsum Fibrosum, Calamina and Concha Margaritifera are ground into 100～200 order fine powders behind the calcine respectively; It is stand-by that Myrrha, Olibanum are ground into 100～200 order fine powders after the parch respectively; By above-mentioned prescription other medicines are ground into 100～200 order fine powders, the mix homogeneously of all putting together, and adding ethanol aerosol is modulated into spray.Other project should meet 2000 editions spray projects of Pharmacopoeia of People's Republic of China relevant requirements.
Claims (3)
1, a kind of Chinese medicine preparation for the treatment of burn is characterized in that it being to be made by following bulk drugs:
Gypsum Fibrosum Preparatum 30～45, Calamina (calcined and quenched) 30～45, Calcitum rubrum 20～35, Ophicalcitum 28～35,
Endoconcha Sepiae 10～18, Myrrha (parched) 6～10, Olibanum (parched) 4～8, Margarita 1～3, calcined Concha Margaritifera 3～6.
2, Chinese medicine preparation according to claim 1 is characterized in that it being to be made by following bulk drugs:
Gypsum Fibrosum Preparatum 35, Calamina (calcined and quenched) 35, Calcitum rubrum 28, Ophicalcitum 32, Endoconcha Sepiae 13, Myrrha (parched) 9, Olibanum (parched) 5, Margarita 1.5, calcined Concha Margaritifera 4.3.
3,, it is characterized in that said medicament is said ointment, spray, a water preparation on any pharmaceutics according to claim 1,2 described Chinese medicine preparation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03111500 CN1183950C (en) | 2003-04-16 | 2003-04-16 | Chinese herbal medicine preparation for treating burns |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03111500 CN1183950C (en) | 2003-04-16 | 2003-04-16 | Chinese herbal medicine preparation for treating burns |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1444967A CN1444967A (en) | 2003-10-01 |
| CN1183950C true CN1183950C (en) | 2005-01-12 |
Family
ID=27814574
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 03111500 Expired - Lifetime CN1183950C (en) | 2003-04-16 | 2003-04-16 | Chinese herbal medicine preparation for treating burns |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1183950C (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100370998C (en) * | 2005-10-13 | 2008-02-27 | 李杰春 | Chinese medicinal preparation for treating sore, and wound and turn and scald |
| CN100402074C (en) * | 2006-04-19 | 2008-07-16 | 刘子会 | A Chinese medicinal ointment for promoting wound healing after anal fistula operation and preparation method thereof |
| EP3552610A4 (en) * | 2016-12-09 | 2019-12-18 | JFE Mineral Company, Ltd. | INORGANIC COMPOSITION HAVING EXCELLENT PROPERTIES OF PROGRESSIVE RELEASE OF ZINC IONS, AND PROCESS FOR PRODUCING THE SAME |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102652763A (en) * | 2011-03-01 | 2012-09-05 | 上海交通大学医学院附属第三人民医院 | Traditional Chinese medicine preparation for treating burn and scald and preparation method thereof |
| CN103028044B (en) * | 2012-12-08 | 2014-07-16 | 浙江大学 | Paste for treating burns and scalds |
| CN107669926A (en) * | 2017-10-19 | 2018-02-09 | 王守文 | Burned muscle reproducing dissipates |
| CN113476493A (en) * | 2021-07-29 | 2021-10-08 | 谢吉伟 | Scald ointment and preparation method thereof |
-
2003
- 2003-04-16 CN CN 03111500 patent/CN1183950C/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100370998C (en) * | 2005-10-13 | 2008-02-27 | 李杰春 | Chinese medicinal preparation for treating sore, and wound and turn and scald |
| CN100402074C (en) * | 2006-04-19 | 2008-07-16 | 刘子会 | A Chinese medicinal ointment for promoting wound healing after anal fistula operation and preparation method thereof |
| EP3552610A4 (en) * | 2016-12-09 | 2019-12-18 | JFE Mineral Company, Ltd. | INORGANIC COMPOSITION HAVING EXCELLENT PROPERTIES OF PROGRESSIVE RELEASE OF ZINC IONS, AND PROCESS FOR PRODUCING THE SAME |
| US10987380B2 (en) | 2016-12-09 | 2021-04-27 | Jfe Mineral Company, Ltd. | Hydrozincite containing zinc carbonate hydroxide hydrate and method of making |
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| Publication number | Publication date |
|---|---|
| CN1444967A (en) | 2003-10-01 |
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