CN117898794B - Shock wave system and shock wave control method - Google Patents

Abstract

The application relates to a shock wave system and a shock wave control method. The shock wave system comprises a first shock wave component, a second shock wave component and a shock wave energy generator, wherein the expansion range corresponding to the first shock wave component is smaller than the expansion range corresponding to the second shock wave component, the first shock wave component is used for expanding according to the applied pressure when being positioned in the preset range of an impacted object and converting high-pressure pulse emitted by the shock wave energy generator into shock wave energy to act on the impacted object, the second shock wave component is used for expanding according to the applied pressure when being positioned in the preset range of the impacted object after the shock wave energy acts on the impacted object and the first shock wave component reaches the sufficient expansion condition, and the impacted object reaches the preset crushing condition when the expanded second shock wave component reaches the sufficient expansion condition. By adopting the system, the accuracy of shock wave control can be improved.

Description

Shock wave system and shock wave control method

Technical Field

The application relates to the technical field of shock waves, in particular to a shock wave system and a shock wave control method.

Background

With the continuous development and improvement of the shock wave technology, the application field of the shock wave technology is further expanded. The shock wave technology is widely used in the medical field, the industrial field, the agricultural field, and the like. For example, in the medical field, calcifications in blood vessels or in the cardiovascular system are eliminated by means of shock waves.

In the traditional technology, the mode of directly sending the shock wave energy to the impacted object by using the shock wave component with fixed size is limited, so that the shock wave is difficult to accurately control, the shock effect is poor, and the treatment requirement is difficult to reach.

Disclosure of Invention

In view of the above, it is desirable to provide a shock wave system and a shock wave control method that can improve accuracy.

In a first aspect, the application provides a shock wave system comprising a first shock wave component, a second shock wave component and a shock wave energy generator, wherein the first shock wave component and the second shock wave component expand under the condition of applying pressure, and the expansion range corresponding to the first shock wave component is smaller than the expansion range corresponding to the second shock wave component.

The first shock wave member expands according to an applied pressure when positioned within a preset range of an impacted object, and converts a high-pressure pulse emitted from the shock wave energy generator into shock wave energy to act on the impacted object while being connected to the shock wave energy generator.

The second shock wave member is used for expanding according to the applied pressure when being positioned within the preset range of the impacted object after the impact wave energy acts on the impacted object and the first shock wave member reaches a sufficient expansion condition, wherein the impacted object reaches a preset crushing condition when the expanded second shock wave member reaches the sufficient expansion condition.

The shock wave energy generator is used for sending out high-voltage pulse under the condition of being connected with the expanded first shock wave component.

In a second aspect, the present application further provides a shock wave control method, which is applied to the shock wave system, where the method includes:

Expanding the first shock wave member according to a first preset pressure under the condition that the first shock wave member is positioned within a preset range of an impacted object;

Controlling the shock wave energy generator to emit a preset number of pulses under the condition that the shock wave energy generator is connected with the expanded first shock wave component, and converting the pulses into shock wave energy through the first shock wave component so as to act the shock wave energy on the impacted object;

after all the pulses of the preset number are sent out, expanding the first shock wave component according to a second preset pressure;

Under the condition that the expanded first shock wave component does not reach a sufficient expansion condition, contracting the first shock wave component according to the reduced pressure, and returning to the step of expanding the first shock wave component according to the first preset pressure to continue to execute after a preset time interval;

Expanding the second shock wave component according to a second preset pressure when the second shock wave component is positioned within a preset range of an impacted object under the condition that the expanded first shock wave component reaches a sufficient expansion condition;

and under the condition that the expanded second shock wave component reaches the sufficient expansion condition, determining that the impacted object reaches a preset crushing condition.

In a third aspect, the present application also provides a computer device comprising a memory storing a computer program and a processor implementing the steps of the method described above when the processor executes the computer program.

In a fourth aspect, the present application also provides a computer readable storage medium having stored thereon a computer program which when executed by a processor performs the steps of the method described above.

In a fifth aspect, the application also provides a computer program product comprising a computer program which, when executed by a processor, implements the steps of the method described above.

The shock wave system comprises a first shock wave component, a second shock wave component and a shock wave energy generator, wherein the first shock wave component and the second shock wave component expand under the condition of applying pressure, and the expansion range corresponding to the first shock wave component is smaller than the expansion range corresponding to the second shock wave component. The device comprises a first shock wave component, a shock wave energy generator, a first shock wave component and a first shock wave component, wherein the first shock wave component is used for expanding according to the applied pressure when being positioned in a preset range of an impacted object and converting high-pressure pulse sent by the shock wave energy generator into shock wave energy under the condition of being connected with the shock wave energy generator so as to act on the impacted object, the shock wave energy generator is used for sending high-pressure pulse under the condition of being connected with the expanded first shock wave component, and the expansion range corresponding to the first shock wave component is smaller, so that the transfer efficiency of the shock wave energy is higher, the focusing effect is better, and the shock wave energy is accurately transferred to the impacted object. The impact wave energy acts on the impacted object, at least part of the impacted object is crushed, the expansion range corresponding to the first impact wave component is smaller and cannot be used for accurately judging the crushing condition of the impacted object, so that the second impact wave component is used for expanding according to the applied pressure when the impact wave energy acts on the impacted object and the first impact wave component reaches the sufficient expansion condition under the condition that the impact wave energy acts on the impacted object and the first impact wave component reaches the sufficient expansion condition, wherein the impacted object reaches the predetermined crushing condition under the condition that the expanded second impact wave component reaches the sufficient expansion condition, the expansion range corresponding to the second impact wave component is larger, the crushing condition of the impacted object can be accurately judged compared with the first impact wave component, and the accuracy of impact wave control is further improved.

Drawings

In order to more clearly illustrate the embodiments of the present application or the technical solutions in the related art, the drawings that are required to be used in the embodiments or the related technical descriptions will be briefly described, and it is apparent that the drawings in the following description are only some embodiments of the present application, and other drawings may be obtained according to the drawings without inventive effort for those skilled in the art.

Fig. 1 is a block diagram of a shock wave system according to an embodiment of the present application.

Fig. 2 is a block diagram of another shock wave system according to an embodiment of the present application.

Fig. 3 is a schematic flow chart of a shock wave control method according to an embodiment of the present application.

Fig. 4 is a flowchart illustrating a step of obtaining an impacted object that is at least partially broken according to an embodiment of the present application.

Fig. 5 is a simplified flow chart of a shock wave control method according to an embodiment of the present application.

Fig. 6 is an internal structure diagram of a computer device according to an embodiment of the present application.

Detailed Description

The present application will be described in further detail with reference to the drawings and examples, in order to make the objects, technical solutions and advantages of the present application more apparent. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the application.

In one exemplary embodiment, as shown in FIG. 1, a shock wave system 100 is provided that includes a first shock wave member 102, a second shock wave member 104, and a shock wave energy generator 106, the first shock wave member 102 and the second shock wave member 104 expanding upon application of pressure, the expansion range of the first shock wave member 102 being less than the expansion range of the second shock wave member.

The first shock wave member 102 is configured to expand according to an applied pressure when positioned within a predetermined range of an impacted object and, when coupled to the shock wave energy generator 106, to convert high pressure pulses emitted by the shock wave energy generator 106 into shock wave energy to act on the impacted object.

In some embodiments, the first shock wave member 102 has a deformation characteristic, and the application of pressure causes deformation of the first shock wave member 102 to achieve an expansion effect.

In some embodiments, the first shock wave member 102 comprises an expandable assembly. Wherein the configuration of the expandable assembly changes with pressure, and the expandable assembly is in an expanded state and increases in volume when pressure is applied, i.e., when the expandable assembly is subjected to an expansion pressure. It will be appreciated that when the first shock wave member 102 is positioned within a predetermined range of the impacted object, the expandable assembly of the first shock wave member 102 may be considered to reach the impacted object, and the expandable assembly may be expanded in response to the applied pressure.

In some embodiments, the first shock wave member 102 may be, but is not limited to, a balloon catheter. The expandable assembly may be, but is not limited to, a balloon.

In some embodiments, the expanded first shock wave member 102 may be in contact with at least a portion of the impacted object. It will be appreciated that the shock wave energy will act more precisely on at least a portion of the contact with the first shock wave member 102.

In some embodiments, the first shock wave member 102 is configured to expand according to a first predetermined pressure applied when positioned within a predetermined range of the impacted object and to expand according to a second predetermined pressure applied after the impact wave energy has been applied to the impacted object. The second preset pressure is greater than the first preset pressure. It will be appreciated that after the impact wave energy has been applied to the impacted object, at least a portion of the impacted object is broken, and after a second, greater predetermined pressure has been applied and at least a portion of the impacted object is broken, the first shock wave element 102 will expand more fully, at which time the expanded first shock wave element 102 will not be broken enough if a fully expanded condition is not reached, without having to replace the second shock wave element with a greater expansion range. If the expanded first shock wave member 102 reaches a fully expanded condition and the degree of fracture of the impacted object is sufficient, it is necessary to replace the second shock wave member having a larger expansion range.

In some embodiments, both the first and second shock wave members 102, 104 comprise expandable assemblies. The fully expanded condition may be, but is not limited to, uniform expansion of the expandable assembly. It will be appreciated that if the degree of fragmentation of the impacted object is sufficient, then there is sufficient room for the expandable assembly to expand, at which point the expansion of the expandable assembly is uniform. If the impact object is not broken enough, the expandable element does not have enough space to expand, and at this time, the expansion of the expandable element is limited by the impact object, and the contact portion of the impact object cannot be fully expanded, which may result in uneven expansion of the expandable element.

In some embodiments, a second predetermined pressure is applied to the expandable assembly by injecting the mixed saline and imaging fluid, and upon application of the second predetermined pressure, it is determined whether the expandable assembly has reached a fully expanded condition. Wherein an expandable assembly that achieves a fully expanded condition may be considered to have no or insignificant relief features. The concave-convex feature may be a mid-waist drum or caused by a stenotic or obstructive tissue.

In some embodiments, the imaging subsystem of the shockwave system may include a contrast device. The contrast device may be configured to determine whether the expandable assembly has reached a fully expanded condition upon application of a second predetermined pressure.

In some embodiments, the second preset pressure comprises two different magnitudes of expansion pressure. And under the condition that the morphological characteristics of the expandable assembly do not reach the preset judging conditions under the condition that smaller expanding pressure is applied, applying larger expanding pressure to the expandable assembly, and judging whether the expandable assembly reaches the full expanding conditions under the condition that larger expanding pressure is applied.

In some embodiments, the first and second shock wave members may be balloon catheters. The expandable assembly is referred to as a balloon. The second preset pressure may include an expansion pressure of 6atm and an expansion pressure of 8 atm. The balloon was inflated by injecting a saline solution and an imaging solution mixed in a ratio of 1:1, and the inflation pressure was 6atm. Including but not limited to using DSA angiographic equipment to examine the balloon location, the balloon morphology saturation was good at 6atm pressure, and the balloon was considered to reach a fully expanded condition without the presence of a mid-section waist drum or overt features of irregularities due to stricture or obstructing tissue. If the characteristics are not significantly unfavorable for observation, the observation can be performed after the pressure is appropriately increased to 8 atm.

In some embodiments, the expansion range includes a maximum degree of expansion. The fully expanded condition may be, but is not limited to, the shock wave member reaching a maximum extent of expansion after expansion.

In some embodiments, the expansion range includes a maximum expansion diameter. The fully expanded condition may be, but is not limited to, the diameter of the expandable assembly after expansion reaching a maximum expanded diameter. It is understood that the maximum expanded diameter refers to the maximum diameter to which the expandable assembly in the shock wave member can expand.

In some embodiments, the first shock wave member 102 is configured to contract according to the reduced pressure in the event that a sufficient expansion condition is not reached after expansion according to the applied second preset pressure, and to expand again according to the applied first preset pressure after a preset time interval, to convert the high pressure pulse from the shock wave energy generator 106 into shock wave energy to release a new round of shock waves. It will be appreciated that in order to ensure the effect of the shock wave energy and improve the accuracy of shock wave control, the first shock wave member 102 is discontinuously used, and the first shock wave member 102 is continuously used after a preset time interval, so that the accuracy of shock wave control can be ensured.

In some embodiments, the impacted objects are distributed in the cavity, the size of the space in the cavity is fixed, if the distribution area of the impacted objects is larger, the space remaining in the cavity is smaller, and at the moment, the shock wave component with smaller corresponding expansion range is more suitable for the impacted objects. After the impact wave energy acts on the impacted object, at least part of the impacted object is broken, the distribution area of the impacted object is reduced, the residual space in the cavity is increased, and at the moment, the impact wave component with larger corresponding expansion range is more suitable for the impacted object. The impacted object described above may be a cavity or calcified tissue within a blood vessel, or the like.

In some embodiments, the impacted objects are distributed inside the cavity of the target object. The operator can position the shock wave member within a predetermined range of the impacted object after introducing the shock wave member into the cavity.

In some embodiments, the impacted objects are distributed inside the tube or cavity of the target object. An operator may introduce the shock wave member into the interior of the body or cavity and then position it to the impacted object.

In some embodiments, the access cavity needs to pass through a throat, so the shock wave member comprises an assembly of elongate structures.

In some embodiments, the bodies of the first and second shock wave members 102, 104 may be elongate tubular structures, i.e., expandable assemblies. It will be appreciated that in the initial state, the first and second shock wave members 102, 104 are elongate, tubular, capable of passing through a throat into the interior of the cavity, and that when the first or second shock wave members 102, 104 are positioned against an object to be impacted, the expandable assembly in the first or second shock wave members 102, 104 will deform, i.e. expand, in response to the applied pressure. The positioning of the first shock wave member 102 or the second shock wave member 104 within a predetermined range of the impacted object actually means that the expandable assembly of the first shock wave member 102 or the second shock wave member 104 with deformation characteristics is positioned to the impacted object.

In some embodiments, the expansion range corresponding to the second shock wave element 104 matches the distribution area of the impacted object, the shock wave system comprises at least one prior shock wave element, the expansion range corresponding to the prior shock wave element is smaller than the expansion range corresponding to the second shock wave element 104, the prior shock wave element is used as the first shock wave element 102 in sequence according to the ascending order of the expansion range, the second shock wave element 104 is used for expanding according to the applied pressure when the shock wave energy acts on the impacted object and the last prior shock wave element reaches the sufficient expansion condition after the shock wave energy acts on the impacted object, and the last prior shock wave element refers to the prior shock wave element with the largest expansion range in the at least one prior shock wave element.

The preceding shockwave member refers to a shockwave member used before the second shockwave member 104 is used. It will be appreciated that at least one prior shock wave member will be positioned as the first shock wave member 102 within the predetermined range of the impacted object before the second shock wave member 104 is positioned within the predetermined range of the impacted object.

It will be appreciated that the expansion range corresponding to the second shock wave member 104 matches the distribution area of the impacted object, i.e. after the second shock wave member 104 has been fully expanded, the degree of fragmentation representing the impacted object in the corresponding distribution area is sufficient to be considered as complete for fragmentation of the impacted object. The larger the distribution area of the impacted object, the more prior shock wave members that are used before the second shock wave member 104. The expansion range of the previous shock wave component used each time is larger than that of the previous shock wave component used last time, so that the shock wave energy can be gradually transferred to a larger range, the shock wave energy can be applied to the impacted object in a larger range, and the impacted object can be accurately crushed in a larger range gradually.

In some embodiments, the shock wave member may be, but is not limited to being, manually positioned by an operator to the impacted object. The shockwave member comprises at least one of the first shockwave member 102 or the second shockwave member 104.

And a second shock wave member 104 for expanding according to an applied pressure when the first shock wave member 102 has reached a fully expanded condition after the shock wave energy has been applied to the impacted object, wherein the impacted object reaches a preset crushing condition when the expanded second shock wave member 104 has reached the fully expanded condition.

In some embodiments, the impacted object may be located inside the cavity of the target object. The second shock wave element 104 matches the space inside the cavity. It will be appreciated that after the object to be impacted inside the cavity is crushed, the space inside the cavity is released, and at this time, the expandable assembly in the second shock wave member 104 can be fully expanded after the pressure is applied, so as to achieve a fully expanded condition, and therefore, the second shock wave member 104 can be used to determine whether the object to be impacted reaches the preset crushing condition. Reaching the preset crushing condition represents the completion of crushing for the impacted object.

In some embodiments, in the event that the expanded second shock wave element 104 does not reach a fully expanded condition after the application of pressure, the second shock wave element 104, when coupled to the shock wave energy generator 106, converts the high pressure pulses emitted by the shock wave energy generator 106 into shock wave energy to apply the shock wave energy to the impacted object. It will be appreciated that both the second shock wave element 104 and the first shock wave element 102 may apply shock wave energy to the impacted object, and that the second shock wave element 104 may continue to expand in response to the applied pressure after applying shock wave energy to the impacted object. If the expanded second shock wave element 104 has not yet reached a fully expanded condition, in the event that a target number of pulses have not been fully emitted, after a preset time interval, the step of converting the high pressure pulses emitted by the shock wave energy generator 106 into shock wave energy in connection with the shock wave energy generator 106, to apply the shock wave energy to the impacted object, is continued.

In some embodiments, the first shock wave member 102 is configured to expand according to a first preset pressure applied when positioned within a preset range of the impacted object and expand according to a second preset pressure applied after the impact wave energy acts on the impacted object, the second preset pressure being greater than the first preset pressure, and the second shock wave member 104 is configured to expand according to the second preset pressure applied when positioned within the preset range of the impacted object when the first shock wave member 102 reaches a fully expanded condition after expanding according to the second preset pressure applied.

In some embodiments, in the event that the expanded second shock wave element 104 does not reach a fully expanded condition after the application of the second preset pressure, the second shock wave element 104 contracts in accordance with the reduced pressure and expands again in accordance with the applied first preset pressure after a preset time interval, and in connection with the shock wave energy generator 106, converts the high pressure pulse emitted by the shock wave energy generator 106 into shock wave energy to apply the shock wave energy to the impacted object.

In some embodiments, the first preset pressure ranges from 4 atmospheres to 5 atmospheres and the second preset pressure ranges from 6 atmospheres to 8 atmospheres. Wherein the atmospheric pressure (atmospheres, atm) is a unit of atmospheric pressure. 1 atm is equal to 101.325 kPa (kilopascals).

In some embodiments, the second shock wave member 104 may be, but is not limited to, a balloon catheter.

In some embodiments, the first and second shock wave members 102, 104 are balloon catheters, wherein the balloon diameter of the first shock wave member 102 ranges from 4 millimeters to 8 millimeters and the balloon diameter of the second shock wave member 104 ranges from 10 millimeters to 12 millimeters.

In some embodiments, the operator may replace the first shock wave member 102 with the second shock wave member 104, with the second shock wave member 104 positioned to the impacted object, in the event that the first shock wave member 102 expands according to the applied second preset pressure to a fully expanded condition. At this point, the first shock wave member 102 is removed. It will be appreciated that the first predetermined pressure applied is used to control the expansion of the first shock wave member 102 or the second shock wave member 104 into contact with at least a portion of the impacted object. The second predetermined pressure applied is used to determine whether the first or second shock wave members 102, 104 are sufficiently expanded.

A shock wave energy generator 106 for emitting a high voltage pulse in connection with the expanded first shock wave element 102.

In some embodiments, the high voltage pulses comprise a predetermined number of pulses, and the shock wave energy generator 106 is configured to release the predetermined number of pulses when connected to the expanded first shock wave member 102 or the expanded second shock wave member 104.

In some embodiments, as shown in FIG. 2, another shock wave system 100 is provided. The shock wave system may include a third shock wave member 108. The third shock wave member 108 is smaller in size than the first shock wave member 102 and the second shock wave member 104. A third shock wave member 108 for converting, in connection with the shock wave energy generator 106, high pressure pulses emitted by the shock wave energy generator 106 into shock wave energy for acting the shock wave energy on the impacted object to obtain an at least partially broken impacted object when positioned within a preset range of the impacted object, and a first shock wave member 102 for expanding according to the applied pressure when positioned within the preset range of the at least partially broken impacted object.

In some embodiments, the third shock wave member 108 is not provided with an expandable assembly, and the dimensions of the third shock wave member 108 may be fixed.

In some embodiments, the third shock wave member 108 may be, but is not limited to, a shock wave microcatheter. The first and second shock wave members 102, 104 may be, but are not limited to, balloon catheters. Before using the balloon catheter, the balloon micro-catheter can be used to apply the impact wave energy to the impacted object, and after at least part of the impacted object is broken, the balloon catheter with larger size can be used.

In some embodiments, electrodes are provided in the shock wave member. The electrical energy is released through electrodes in the shockwave member and converted into acoustic mechanical energy, which propagates to the impacted object.

In some embodiments, the shock wave energy generator 106 comprises an energy host. An energy host may be used to generate the high voltage current.

In some embodiments, the shock wave energy generator 106 comprises a cable. The cable may be used to transmit high voltage current to the electrode.

In some embodiments, the shock wave energy generator may include an energy host, a handle cable, and a catheter cable. The energy host is used for generating high-voltage energy, and the handle cable and the catheter cable are used for high-voltage energy transmission. The shock wave energy generator can aim at shock wave components with different specifications for different purposes, and the purpose of accurately outputting shock waves is achieved by adjusting at least one energy parameter such as different voltage, current or output power. For example, for shockwave components used to eliminate calcification of heart valves, the output voltage ranges from 4KV to 8KV. Whereas for shockwave devices for eliminating vascular calcification, the output voltage ranges from 1.5KV to 4KV.

In some embodiments, different shock wave components may each correspond to a different energy parameter. The energy parameter may comprise at least one of voltage or current or output power, etc. It will be appreciated that the shock wave energy generator 106 may be adapted to each shock wave element by adjusting at least one energy parameter of a different voltage or current or output power, etc., for the purpose of accurately delivering shock waves through each shock wave element, respectively.

In some embodiments, the same shock wave element corresponds to multiple energy parameters, where different energy parameters are applicable to different impacted objects. It will be appreciated that the shockwave system may be applied to a variety of impacted objects, with the energy parameters required for different impacted objects also varying.

In some embodiments, the shock wave energy generator 106 is configured to emit high pressure energy according to the energy parameter in the event that the shock wave element is in contact with the impacted object.

In some embodiments, the shock wave energy generator 106 may acquire energy parameters. It will be appreciated that the operator may choose the energy parameters set for different shock wave components and different impacted objects, or may manually input the energy parameters.

In the shock wave system, the shock wave system comprises a first shock wave component, a second shock wave component and a shock wave energy generator, wherein the first shock wave component and the second shock wave component expand under the condition of applying pressure, and the expansion range corresponding to the first shock wave component is smaller than that corresponding to the second shock wave component. The first shock wave component is used for expanding according to the applied pressure when being positioned in a preset range of the impacted object and converting high-pressure pulse emitted by the shock wave energy generator into shock wave energy when being connected with the shock wave energy generator so as to act on the impacted object, and the shock wave energy generator is used for emitting high-pressure pulse when being connected with the expanded first shock wave component. The impact wave energy acts on the impacted object, at least part of the impacted object is crushed, the expansion range corresponding to the first impact wave component is smaller and cannot be used for accurately judging the crushing condition of the impacted object, so that the second impact wave component is used for expanding according to the applied pressure when the impact wave energy acts on the impacted object and the first impact wave component reaches the sufficient expansion condition under the condition that the impact wave energy acts on the impacted object and the first impact wave component reaches the sufficient expansion condition, wherein the impacted object reaches the predetermined crushing condition under the condition that the expanded second impact wave component reaches the sufficient expansion condition, the expansion range corresponding to the second impact wave component is larger, the crushing condition of the impacted object can be accurately judged compared with the first impact wave component, and the accuracy of impact wave control is further improved.

In some embodiments, the shockwave system further comprises an imaging subsystem. And the image subsystem is used for assisting in positioning the shock wave component to the impacted object. It will be appreciated that the operator may gradually deliver the shockwave device to the lesion through guidance from the imaging subsystem. In the conveying process, the position and the direction of the shock wave component are required to be continuously adjusted, so that the shock wave component can accurately reach the position of the impacted object. Wherein the shock wave member may be a first shock wave member, a second shock wave member or a third shock wave member.

In some embodiments, the shockwave system may position the shockwave member within a predetermined range of the impacted object after introducing the shockwave member into the cavity based on the imaging subsystem.

In some embodiments, the shockwave system may direct the shockwave device into the interior of the body based on the imaging subsystem and then position the shockwave device within a predetermined range of the impacted object.

In some embodiments, the shock wave system may further comprise a computer subsystem and a pressure subsystem. The computer subsystem is used for receiving an input instruction, controlling the shock wave energy generator to emit high-pressure energy according to the input instruction, and controlling the pressure subsystem to apply pressure or decompress to the first shock wave component or the second shock wave component.

In some embodiments, the instructions may be entered by an operator. The instructions may include at least one of an energy parameter or a pressure parameter, etc. It is understood that the pressure subsystem is used to apply pressure or reduced pressure to the first or second shock wave members in accordance with pressure parameters.

In some embodiments, the first shock wave member expands according to the applied pressure, the expanded first shock wave member contacts at least a portion of the impacted object, and the computer subsystem sends a first control signal to the shock wave energy generator according to the input first command, the shock wave energy generator sends a high-voltage current according to the energy parameter carried by the first control signal, the cable transmits the high-voltage current to the electrode in the first shock wave member, and the electrode in the first shock wave member converts the released electric energy into acoustic mechanical energy. The shock wave is transmitted in the expanded first shock wave element, and the shock wave can accurately act on the impacted object due to the fact that the expanded first shock wave element is in contact with at least part of the impacted object, and the process is the release of shock wave energy.

After the acoustic mechanical energy is applied to the impacted object, i.e., after the shock wave energy is released, the first shock wave member 102 expands according to the applied pressure, and contracts according to the reduced pressure if the expanded first shock wave member 102 does not reach a fully expanded condition. It will be appreciated that by alternating between pressurization and depressurization, it is ensured that excessive compression is avoided and that the first shock wave member is in uniform contact with the area of the impacted object, so that the shock wave acts more uniformly and effectively on the impacted object.

The computer system sends a second control signal to the pressure subsystem according to the second input command after a preset time interval, the pressure subsystem applies pressure to the first shock wave component according to the pressure parameter carried by the second control signal, and the first shock wave component expands again according to the applied pressure. Repeating the above operation until reaching the requirement of reaming or impacting the impacting object.

In some embodiments, after the shock wave energy is released, the computer subsystem sends a third control signal to the pressure subsystem according to a third input command, and the pressure subsystem applies pressure to the first shock wave element according to a pressure parameter carried by the third control signal. The pressure parameter carried by the third control signal is not smaller than the pressure parameter carried by the second control signal. It will be appreciated that after the action of the shock wave, at least a portion of the impacted object will soften, loosen, differentiate or shatter, etc., such that the expandable space of the first shock wave member is larger, and at this time, a greater pressure is applied to the first shock wave member to allow the first shock wave member to expand more fully, and if the first shock wave member cannot expand fully, i.e., a fully expanded condition is not reached, the first shock wave member is not replaced and continues for the next shock wave release until the first shock wave member expands fully. If the first shock wave member expands sufficiently, i.e., a sufficient expansion condition is reached, the first shock wave member completes reaming or impacting the impacted object, and the first shock wave member is replaced with a corresponding second shock wave member having a larger expansion range.

In some embodiments, after the computer subsystem obtains the input instruction, the instruction is parsed to obtain the corresponding control parameter, so as to generate a notification signal carrying the control parameter. The control parameters may include at least one of an energy parameter or a pressure parameter, etc.

In some embodiments, the number and intensity of the shockwave release may be controlled by controlling the number and parameters of the pulses emitted by the shockwave energy generator. The energy parameter carried by the first control signal may comprise, for example, a preset number of pulses. For example, the operator selects a number of pulses of 10, then the shock wave energy generator may release 10 pulses at a time. And the shock wave energy generator is used for releasing the preset number of pulses carried by the first control signal under the condition that the first shock wave component or the second shock wave component is contacted with the impacted object.

In some embodiments, the pressure subsystem is a hydraulic system through which pure water, contrast fluid, or saline is pumped into the expandable assembly of the first shock wave member or the second shock wave member to expand to a first preset pressure or a second preset pressure.

In some embodiments, the pressure subsystem is configured to apply a first preset pressure to the first or second shock wave element in accordance with a pressure parameter carried by the second control signal. It will be appreciated that the pressure parameter carried by the second control signal is used to characterize the first preset pressure. The pressure subsystem is also used for applying a second preset pressure to the first shock wave component or the second shock wave component according to the pressure parameter carried by the third control signal. The pressure parameter carried by the third control signal is used for representing the second preset pressure.

In some embodiments, in the case that the second shock wave member does not reach a sufficient expansion condition after being expanded according to the applied second preset pressure, the expanded second shock wave member is in contact with at least part of the impacted object according to the applied first preset pressure, and the computer subsystem sends a first control signal to the shock wave energy generator according to the input first instruction, the shock wave energy generator sends a high-voltage pulse according to the energy parameter carried by the first control signal, the cable transmits the high-voltage pulse to an electrode in the second shock wave member, and the electrode in the second shock wave member converts the high-voltage pulse into shock wave energy. After the impact wave energy acts on the impacted object, i.e. after the impact wave energy is released, the second impact wave component expands according to the applied second preset pressure, and reaming or impacting the impacted object is completed under the condition that the expanded second impact wave component reaches a sufficient expansion condition.

In some embodiments, the computer subsystem sends a fourth control signal to the pressure subsystem in accordance with the fourth command input. The pressure subsystem is used for decompressing the first shock wave component or the second shock wave component according to the fourth control signal, so that the expansion degree of the first shock wave component or the second shock wave component is reduced and the first shock wave component or the second shock wave component is far away from the impacted object.

In some embodiments, the first and second shock wave members are both balloon catheters. The shock wave system comprises a prior shock wave component A1 with a balloon diameter of 6mm, a prior shock wave component A2 with a balloon diameter of 8mm, a prior shock wave component A3 with a balloon diameter of 10mm, a prior shock wave component A4 with a balloon diameter of 12mm, a prior shock wave component A5 with a balloon diameter of 12mm and a second shock wave component B1 with a balloon diameter of 18 mm.

The method comprises the steps of firstly determining A1 as a first shock wave component, positioning A1 to the impacted object, fully contacting A1 after filling and expanding by injecting developing solution and/or normal saline mixed liquid with the impacted object, sending out high-pressure energy by a shock wave energy generator 104, carrying out high-pressure energy transmission through a handle cable and/or a conduit cable, converting shock wave energy released by shock wave energy release of an electrode in A1 into sound wave mechanical energy, transmitting the sound wave mechanical energy to the impacted object, softening/loosening/differentiating the impacted object, expanding A1 by further pressurizing A1, realizing expansion treatment on the inside of the impacted object, after the A1 is fully expanded, re-selecting A2 with larger balloon diameter as a first shock wave component, repeating the expansion treatment on the inside of the target object, after the A2 is fully expanded, sequentially selecting A3, A4 and A5 as first shock wave components, repeating the expansion steps of A1 and B5, and fully expanding B1, wherein the conditions are fully represented by the preset conditions. Wherein the shock wave energy release may be achieved by a hydro-electric reaction. It will be appreciated that the inside of the target object may be a cavity or a tube, if the distribution area of the impacted object inside the target object is smaller, the residual space inside the target object is larger, and the A1 with the too small balloon diameter is selected as the first shock wave component, and may not be contacted by at least part of the impacted object, so that A2 or A3 or A4 or A5 with the larger balloon diameter may be directly selected as the first shock wave component, and the steps are performed from the A2 or A3 or A4 or A5 with the larger balloon diameter.

In some embodiments, a shockwave system may be used to eliminate shocked objects within the cavity. The shock wave system may be used to eliminate calcification of the heart valve. At this time, the first shock wave component and the second shock wave component are balloon catheters, the diameter of the balloon ranges from 5mm to 20mm, and the length of the balloon ranges from 15mm to 65mm after the balloon catheters are filled with liquid.

In some embodiments, the balloon in the shock wave member may be filled with a mixed liquid of saline and contrast fluid to a first preset pressure or a second preset pressure.

In some embodiments, the shockwave system may also be used to eliminate shocked objects within the tube. For example, a shockwave system may be used to eliminate vascular calcification. At this time, the first shock wave component and the second shock wave component are balloon catheters, and after the balloon catheters are filled with liquid, the diameter of the balloon ranges from 2mm to 5mm, and the length of the balloon ranges from 5mm to 15mm.

In some embodiments, the shock wave system is in the process of eliminating calcification in a blood vessel, wherein a balloon in a shock wave component enters a calcified lesion site, the balloon after balloon filling is fully contacted with the calcified lesion site by injecting a developing solution and/or a normal saline mixed liquid, a high-voltage energy is sent out by a shock wave energy generator, voltage or current pulse energy transmission is carried out by a handle cable and/or a conduit cable, high-voltage or current energy release (electrohydraulic reaction) is carried out on an electrode in the balloon, and the released electric energy is converted into sound wave mechanical energy, and the sound wave mechanical energy is transmitted to the calcified lesion site to soften/loosen/differentiate the calcified part.

In some embodiments, the shock wave system includes a generator activation button for triggering the shock wave energy generator to emit a high voltage pulse.

In some embodiments, the computer subsystem may send a first control signal to the shock wave energy generator to control the shock wave energy generator to emit a high voltage pulse in response to a trigger operation for the generator start button.

In some embodiments, the computer subsystem may determine that the generator start key is in effect in response to an enabling operation for the generator start key, and respond to a triggering operation for the generator start key if the generator start key is in effect. It can be appreciated that an operator can activate the generator start button, and then trigger the generator start button to quickly and conveniently input the first instruction. The generator start button is a human-computer interaction element for inputting a first instruction.

In some embodiments, the computer subsystem may obtain a trigger operation for the generator start key in the event that the generator start key is pressed.

The various components of the above described shockwave system may be implemented in whole or in part by software, hardware, and combinations thereof. The above components may be embedded in hardware or may be independent of a processor in the computer device, or may be stored in software in a memory in the computer device, so that the processor may call and execute operations corresponding to the above components.

Based on the same inventive concept, the embodiment of the application also provides a shock wave control method. The implementation of the solution provided by the method is similar to that described in the above system, so the specific limitations of one or more embodiments of the shock wave control method provided below may be referred to above for limitations of the shock wave system, and will not be repeated here.

In an exemplary embodiment, as shown in fig. 3, a shock wave control method is provided, and the method is exemplified as being applied to a shock wave system, and includes the following steps 302 to 312.

Step 302, expanding the first shock wave member according to a first preset pressure, in case the first shock wave member is positioned within a preset range of the impacted object.

Step 304, controlling the shock wave energy generator to emit a predetermined number of pulses with the shock wave energy generator coupled to the expanded first shock wave element, the pulses being converted to shock wave energy by the first shock wave element to apply the shock wave energy to the impacted object.

Step 306, expanding the first shock wave member according to the second preset pressure after the preset number of pulses are all issued.

And 308, in the case that the expanded first shock wave component does not reach the sufficient expansion condition, contracting the first shock wave component according to the reduced pressure, and returning to the step of expanding the first shock wave component according to the first preset pressure to continue to execute after a preset time interval.

And step 310, expanding the second shock wave component according to a second preset pressure when the second shock wave component is positioned within the preset range of the impacted object under the condition that the expanded first shock wave component reaches a sufficient expansion condition.

Step 312, determining that the impacted object reaches the preset crushing condition when the expanded second shock wave member reaches the fully expanded condition.

In some embodiments, the method further comprises the step of obtaining an at least partially crushed impacted object before expanding the first shock wave member according to the first preset pressure, in case the first shock wave member is positioned within the preset range of the impacted object. As shown in fig. 4, a flow diagram of the steps of obtaining an at least partially crushed impacted object is provided, including the following steps 402-404.

Step 402, controlling the shock wave energy generator to emit a high voltage pulse with the shock wave microcatheter positioned within a preset range of the impacted object and the shock wave microcatheter connected to the shock wave energy generator.

At step 404, the high voltage pulse is converted into shock wave energy by the shock wave microcatheter to apply the shock wave energy to the impacted object to obtain an at least partially crushed impacted object.

In some embodiments, the method further comprises determining a shock wave component in at least one prior shock wave component as a first shock wave component according to ascending order of expansion ranges, wherein the expansion range corresponding to the prior shock wave component is smaller than the expansion range corresponding to the second shock wave component, expanding the second shock wave component according to a second preset pressure when the second shock wave component is positioned within the preset range of the impacted object under the condition that the expanded first shock wave component reaches the full expansion condition, and expanding the second shock wave component according to the second preset pressure when the second shock wave component is positioned within the preset range of the impacted object under the condition that the first shock wave component reaches the full expansion condition.

In some embodiments, after the preset time interval, returning to the step of expanding the first shock wave member in accordance with the first preset pressure continues, including returning to the step of expanding the first shock wave member in accordance with the first preset pressure after the preset time interval if a target number of pulses are not all issued, the target number being an integer multiple of the preset number.

In some embodiments, the predetermined number of pulses refers to one cycle of pulses. For example, the target number may be 10 times the preset number, and then in case that the pulses of 10 cycles are not all emitted, the step of returning to expanding the first shock wave member according to the first preset pressure continues after the preset time interval.

In some embodiments, the shockwave system may stop continuing to perform the step of expanding the first shockwave member according to the first preset pressure if the expanded first shockwave member does not reach a sufficient expansion condition and the target number of pulses are all issued. It can be understood that after one shock wave member is used for a plurality of times, that is, after the same shock wave member emits the pulses with the target number, the breaking degree of the impacted object is still insufficient, and the shock wave member can be stopped to be used under the condition that the shock wave member cannot reach the sufficient expansion condition, so as to avoid the waste of energy resources.

In some embodiments, the shockwave system may be configured such that the operator may self-determine a subsequent operation if the expanded first shockwave member has not reached a fully expanded condition and a target number of pulses have been issued. For example, the operator may remove the first shock wave member from the impacted object and continue to position the first shock wave member to the impacted object after a period of time.

In some embodiments, the shock wave control methods provided by the present application may be used to eliminate aortic valve calcification. As shown in fig. 5, a simple flow diagram of a shock wave control method is provided, which includes the following steps:

step 502, after confirming the target lesion site, a contrast agent is injected to confirm the aortic valve calcification site, wherein the balloon dilates the valve if necessary.

At step 504, after balloon catheter placement into active valve calcification positioning, the prior shock wave member A1 fills to 2 to 4 atmospheres.

Step 506, the generator is activated to activate a key and a key release pulse is pressed.

After a period of step 508,1, i.e., 8 to 15 pulses, the preceding shockwave member A1 fills to 5 to 7 atmospheres to dilate the calcified region, observing whether the preceding shockwave member A1 can sufficiently dilate.

If not, step 510, the prior shock wave member A1 is depressurized, ensuring that no bubbles remain, waiting 5 to 30 seconds, and the prior shock wave member A1 is refilled to 2 to 4 atmospheres, and 1 cycle pulse release is performed.

If yes, step 512, the previous shock wave member A2 having a balloon diameter 1 to 2mm greater than A1 is replaced for the catheter guidewire.

At step 514, the catheter fills to 5 to 7 atmospheres to dilate the calcified area, observing whether the prior shock wave member A2 can sufficiently dilate.

If not, step 516, the preceding shock wave member A2 is depressurized, ensuring that no bubbles remain, waiting 5 to 30 seconds, and the preceding shock wave member A2 is refilled to 2 to 4 atmospheres, and 1 cycle pulse release is performed.

If yes, step 518, the previous shock wave element A3 with a balloon diameter of 8mm is replaced for insertion into the catheter guidewire.

Step 520, the preceding shockwave member A3 fills to 5 to 7 atmospheres to dilate the calcified region, observing whether the preceding shockwave member A3 can sufficiently dilate.

If not, step 522, the pressure of the preceding shock wave member A3 is reduced to ensure that no bubbles remain, waiting for 5 to 30 seconds, and the preceding shock wave member A3 is refilled to 2 to 4 atmospheres, and 1 cycle of pulse release is performed.

If the second shock wave member B1 with the balloon diameter of 12 mm is replaced, the catheter guidewire is inserted, the second shock wave member B1 fills up to 5 to 7 atmospheres to dilate the calcified area, and the second shock wave member B1 can be sufficiently dilated, step 524, wherein the goal is to restore the aortic valve closure diameter to 14 mm.

If so, the treatment is completed to withdraw the second shock wave element B1, step 526.

It should be understood that, although the steps in the flowcharts related to the above embodiments are sequentially shown as indicated by arrows, these steps are not necessarily sequentially performed in the order indicated by the arrows. The steps are not strictly limited to the order of execution unless explicitly recited herein, and the steps may be executed in other orders. Moreover, at least some of the steps in the flowcharts described in the above embodiments may include a plurality of steps or a plurality of stages, which are not necessarily performed at the same time, but may be performed at different times, and the order of the steps or stages is not necessarily performed sequentially, but may be performed alternately or alternately with at least some of the other steps or stages.

In one exemplary embodiment, a computer device is provided, the internal structure of which may be as shown in FIG. 6. The computer device includes a processor, a memory, an input/output interface, a communication interface, a display unit, and an input means. The processor, the memory and the input/output interface are connected through a system bus, and the communication interface, the display unit and the input device are connected to the system bus through the input/output interface. Wherein the processor of the computer device is configured to provide computing and control capabilities. The memory of the computer device includes a non-volatile storage medium and an internal memory. The non-volatile storage medium stores an operating system and a computer program. The internal memory provides an environment for the operation of the operating system and computer programs in the non-volatile storage media. The input/output interface of the computer device is used to exchange information between the processor and the external device. The communication interface of the computer device is used for carrying out wired or wireless communication with an external terminal, and the wireless mode can be realized through WIFI, a mobile cellular network, NFC (near field communication) or other technologies. The computer program is executed by a processor to implement a shock wave control method. The display unit of the computer device is used for forming a visual picture, and can be a display screen, a projection device or a virtual reality imaging device. The display screen can be a liquid crystal display screen or an electronic ink display screen, and the input device of the computer equipment can be a touch layer covered on the display screen, can also be a key, a track ball or a touch pad arranged on the shell of the computer equipment, and can also be an external keyboard, a touch pad or a mouse and the like.

It will be appreciated by those skilled in the art that the structure shown in FIG. 6 is merely a block diagram of some of the structures associated with the present inventive arrangements and is not limiting of the computer device to which the present inventive arrangements may be applied, and that a particular computer device may include more or fewer components than shown, or may combine some of the components, or have a different arrangement of components.

In an exemplary embodiment, a computer device is provided, comprising a memory and a processor, the memory having stored therein a computer program, the processor performing the steps of the method embodiments described above when the computer program is executed.

In one embodiment, a computer-readable storage medium is provided, on which a computer program is stored which, when executed by a processor, implements the steps of the method embodiments described above.

In an embodiment, a computer program product is provided, comprising a computer program which, when executed by a processor, implements the steps of the method embodiments described above.

It should be noted that, the user information (including but not limited to user equipment information, user personal information, etc.) and the data (including but not limited to data for analysis, stored data, presented data, etc.) related to the present application are both information and data authorized by the user or sufficiently authorized by each party, and the collection, use and processing of the related data are required to meet the related regulations.

Those skilled in the art will appreciate that implementing all or part of the above-described methods in accordance with the embodiments may be accomplished by way of a computer program stored on a non-transitory computer readable storage medium, which when executed may comprise the steps of the embodiments of the methods described above. Any reference to memory, database, or other medium used in embodiments provided herein may include at least one of non-volatile and volatile memory. The nonvolatile Memory may include Read-Only Memory (ROM), magnetic tape, floppy disk, flash Memory, optical Memory, high density embedded nonvolatile Memory, resistive random access Memory (ReRAM), magneto-resistive random access Memory (Magnetoresistive Random Access Memory, MRAM), ferroelectric Memory (Ferroelectric Random Access Memory, FRAM), phase change Memory (PHASE CHANGE Memory, PCM), graphene Memory, and the like. Volatile memory can include random access memory (Random Access Memory, RAM) or external cache memory, and the like. By way of illustration, and not limitation, RAM can be in various forms such as static random access memory (Static Random Access Memory, SRAM) or dynamic random access memory (Dynamic Random Access Memory, DRAM), etc. The databases referred to in the embodiments provided herein may include at least one of a relational database and a non-relational database. The non-relational database may include, but is not limited to, a blockchain-based distributed database, and the like. The processor referred to in the embodiments provided in the present application may be a general-purpose processor, a central processing unit, a graphics processor, a digital signal processor, a programmable logic unit, a data processing logic unit based on quantum computing, or the like, but is not limited thereto.

The technical features of the above embodiments may be arbitrarily combined, and all possible combinations of the technical features in the above embodiments are not described for brevity of description, however, as long as there is no contradiction between the combinations of the technical features, they should be considered as the scope of the description.

The foregoing examples illustrate only a few embodiments of the application, which are described in detail and are not to be construed as limiting the scope of the application. It should be noted that it will be apparent to those skilled in the art that several variations and modifications can be made without departing from the spirit of the application, which are all within the scope of the application. Accordingly, the scope of the application should be assessed as that of the appended claims.

Claims (10)

1. The shock wave system is characterized by comprising a first shock wave component, a second shock wave component and a shock wave energy generator, wherein the first shock wave component and the second shock wave component expand under the condition of applying pressure, and the expansion range corresponding to the first shock wave component is smaller than the expansion range corresponding to the second shock wave component;

The first shock wave component is used for expanding according to the applied pressure when being positioned in a preset range of an impacted object, and converting high-pressure pulse emitted by the shock wave energy generator into shock wave energy when being connected with the shock wave energy generator so as to act on the impacted object by the shock wave energy;

The second shock wave component is used for expanding according to the applied pressure when being positioned in a preset range of the impacted object after the impact wave energy acts on the impacted object and the first shock wave component reaches a sufficient expansion condition;

The shock wave energy generator is used for sending out high-voltage pulses under the condition of being connected with the expanded first shock wave component;

The first shock wave component is used for expanding according to the first preset pressure when being positioned in the preset range of the impacted object, and expanding according to the second preset pressure when being applied after the impact wave energy acts on the impacted object, wherein the second preset pressure is larger than the first preset pressure;

The second shock wave component is used for expanding according to the applied second preset pressure when the first shock wave component reaches a sufficient expansion condition after expanding according to the applied second preset pressure and is positioned in the preset range of the impacted object;

the shock wave system further comprises an imaging subsystem for assisting in positioning the first shock wave component and the second shock wave component to the impacted object.

2. The shock wave system as in claim 1, wherein the high voltage pulses comprise a predetermined number of pulses, and wherein the shock wave energy generator is configured to release the predetermined number of pulses when connected to the expanded first shock wave member or the expanded second shock wave member.

3. The shock wave system as claimed in claim 1, wherein the first shock wave member is adapted to contract according to the reduced pressure in case a sufficient expansion condition is not reached after expansion according to the applied second preset pressure, and to expand again according to the applied first preset pressure after a preset time interval, converting the high pressure pulse emitted by the shock wave energy generator into shock wave energy to release a new round of shock wave.

4. The shockwave system according to claim 1, wherein said first preset pressure ranges from 4 atmospheres to 5 atmospheres and said second preset pressure ranges from 6 atmospheres to 8 atmospheres.

5. The shock wave system according to any one of claims 1 to 4, wherein the expansion range corresponding to the second shock wave element matches the distribution area of the impacted object, the shock wave system comprising at least one preceding shock wave element, the expansion range corresponding to the preceding shock wave element being smaller than the expansion range corresponding to the second shock wave element;

the preceding shock wave component is used for sequentially serving as a first shock wave component according to the ascending order of the expansion range;

The second shock wave component is used for expanding according to the applied pressure when the last previous shock wave component is positioned within the preset range of the impacted object after the shock wave energy acts on the impacted object and reaches the sufficient expansion condition, and the last previous shock wave component is the previous shock wave component with the largest corresponding expansion range in the at least one previous shock wave component.

6. The shock wave system of claim 5, wherein the first shock wave member and the second shock wave member are both balloon catheters;

the diameter of the balloon of the first shock wave component ranges from 4 mm to 8 mm, and the diameter of the balloon of the second shock wave component ranges from 10 mm to 12 mm.

7. The shock wave system of claim 6, further comprising a shock wave microcatheter for converting high pressure pulses emitted by the shock wave energy generator into shock wave energy when positioned within a predetermined range of the impacted object to apply the shock wave energy to the impacted object to obtain an at least partially crushed impacted object;

the first shock wave member is configured to expand according to an applied pressure when positioned within a preset range of the impacted object that is at least partially broken.

8. The shock wave system of claim 1, further comprising a third shock wave member for converting high pressure pulses emitted by the shock wave energy generator into shock wave energy when positioned within a predetermined range of the impacted object to apply shock wave energy to the impacted object to produce an at least partially broken impacted object, wherein the third shock wave member is smaller in size than the first shock wave member and the second shock wave member.

9. The shock wave system of claim 1, wherein the shock wave energy generator comprises an energy host for generating a high voltage current.

10. The shock wave system of claim 1, wherein the shock wave energy generator comprises a cable for transmitting high voltage current to the electrode.