CN117771139A - A composition containing Cryptomeria fortunei bud extract for repairing skin barrier and its preparation method - Google Patents

Abstract

The invention relates to a skin barrier repairing composition containing cryptomeria bud extract and a preparation method thereof, and belongs to the technical field of skin care products. A composition for repairing skin barrier containing cedar bud extract. The composition includes the following raw materials in parts by weight: 8-13 parts of cedar bud extract, 2-7 parts of bougainvillea extract, and licorice extract. It contains 6-14 parts of algae extract, 1.5-3.0 parts of seaweed extract, 7-16 parts of raspberry extract, 5-8 parts of green thorn fruit oil, and 25-40 parts of solvent. The present invention uses a compound combination of cedar bud extract, Bougainvillea extract, licorice extract, seaweed extract, raspberry extract and green thorn fruit oil to make the composition have antioxidant, moisturizing, moisturizing, improving and repairing properties. The role of the skin barrier.

Description

Composition for repairing skin barrier containing Cryptomeria fortunei bud extract and preparation method thereof

Technical field

The invention belongs to the technical field of skin care products and relates to a skin barrier repairing composition containing cryptomeria bud extract.

Background technique

Skin covers the entire body surface of the human body, accounting for approximately 16% of body weight. It has a dual barrier function. On the one hand, it can prevent the loss of various nutrients, water, and electrolytes in the body, and on the other hand, it can prevent the invasion of harmful or unwanted substances from the outside. Therefore, skin serves as our body’s protective layer and helps us resist damage from harmful substances in the environment.

In daily life, ultraviolet rays, floating dust, bacteria, fungi, and oils, sweat and other substances secreted by the skin in the air can induce pathological changes such as skin oxidative stress, inflammation, and cell apoptosis, and destroy the stability of the skin barrier structure.

When the skin is damaged, such as burns, scalds, etc., keratinocytes can migrate to the damaged site through cell migration, proliferate in large numbers, secrete cytokines and growth factors, and heal the damaged site. Therefore, the migration ability of keratinocytes plays an important role in repairing epidermal damage. Keratin is the main structural protein of the epidermis and a signature component of keratinocytes. The expression of keratin at different stages represents different stages of epidermal cell differentiation. K1 is the first protein synthesized during keratinization and is the main keratin in keratinocytes in the upper basal layer of the epidermis. Loricin is a key component in the assembly process of keratinized envelope, the end product of keratinocyte differentiation, and plays a role in strengthening the skin barrier.

Contents of the invention

The object of the present invention is to provide a composition for repairing skin barrier containing cedar bud extract and a preparation method thereof. The compound combination of pot extract and green thorn fruit oil makes the composition have the functions of antioxidant, moisturizing, moisturizing, improving and repairing the skin barrier.

The purpose of the present invention can be achieved through the following technical solutions:

A composition for repairing skin barrier containing cedar bud extract. The composition includes the following raw materials in parts by weight: 8-13 parts of cedar bud extract, 2-7 parts of bougainvillea extract, and licorice extract. 6-14 parts of natural ingredients, 2-3 parts of seaweed extract, 7-16 parts of raspberry extract, 5-8 parts of green thorn fruit oil, and 25-40 parts of solvent.

As a preferred technical solution of the present invention, Amaranthus sinensis oil, a precious vegetable oil, is rich in unsaturated fatty acids, such as linoleic acid and linolenic acid, and is famous for its unique nourishing and repairing abilities. This oil is unique in that it deeply moisturizes the skin while repairing and strengthening the skin barrier for complete skin protection. The mechanism of action of Amaranthus lucidum oil is that it can increase the mRNA expression of proteins and enzymes such as LOR in the keratinized mantle. The keratinized mantle is the outermost layer of the skin epidermis. Its integrity and health directly affect the health of the skin. When the skin is damaged, the permeability of the keratinized mantle will be affected, and amaranth fruit oil can repair this damage by increasing the expression of related proteins and enzymes, thereby restoring the normal function of the epidermal permeability barrier. In addition, green thorn fruit oil is very rich in nutrients, including a variety of vitamins, minerals and antioxidants, which are also crucial for skin health. The use of green thorn fruit oil can effectively protect the skin, prevent moisture loss and damage from the external environment, and keep the skin soft, smooth and healthy.

As a preferred technical solution of the present invention, seaweed extract and cedar bud extract contain rich polysaccharide substances, such as fucoidan and anthocyanins. These substances have moisturizing and antioxidant properties and can increase the skin's moisturizing properties. moisture content and forms a protective film, helping to maintain the skin's moisture balance.

As a preferred technical solution of the present invention, raspberry extract promotes cell metabolism by increasing the expression of LOR and K1 genes, and achieves the effect of repairing the skin barrier by increasing the relative mobility of skin cells.

As a preferred technical solution of the present invention, the oil of the thorn fruit is rich in unsaturated fatty acids, such as linoleic acid and linolenic acid, which has the effect of moisturizing and repairing the skin barrier. The oil of the thorn fruit can increase the LOR of the keratinized mantle, etc. The mRNA expression of proteins and enzymes repairs the damaged epidermal permeability barrier.

As a preferred technical solution of the present invention, cryptomeria bud extract can stimulate the regeneration of skin cells, enhance the vitality of skin tissue, comprehensively strengthen the skin to resist aging, and contains rich natural moisturizing ingredients, which can effectively maintain the moisture of the skin. , making the skin more hydrated, plump and elastic, while forming a barrier on the surface of the skin to protect the skin from external damage, and has a good anti-allergic effect.

Furthermore, cedar bud extract has the following effects: Promote regeneration of skin tissue structure: Cryptomeria bud extract can stimulate the regeneration of skin cells, enhance the vitality of skin tissue, and help reshape healthy skin structure. Comprehensively strengthen the skin: Cryptomeria bud extract has antioxidant and anti-free radical properties, which can effectively resist the effects of harmful factors in the environment on the skin, thereby comprehensively improving the skin's resistance. Create a moist and plump texture: Cryptomeria bud extract is rich in natural moisturizing ingredients, which can effectively maintain skin moisture and make skin more hydrated, plump and elastic. Form a barrier to protect the skin: Cryptomeria bud extract can form a protective film on the surface of the skin, effectively blocking external stimulation and pollution, thereby protecting the skin from external damage. Anti-allergic effect: Cryptomeria bud extract has good anti-inflammatory and anti-allergic effects, which can effectively relieve skin allergy symptoms, reduce allergic reactions, and make the skin healthier and more comfortable.

As a preferred technical solution of the present invention, the solvent is any one of butanediol, propylene glycol and deionized water.

As a preferred technical solution of the present invention, cryptomeria bud extract and seaweed extract were purchased from Guangzhou Huayu Biotechnology Co., Ltd.; Amaranthin fruit oil was purchased from Guangdong Marumi Biotechnology Co., Ltd.; licorice extract was purchased from Hebei Peng Yu Biotechnology Co., Ltd.; Bougainvillea extract was purchased from Ningxia Vanilla Biotechnology Co., Ltd.

The invention discloses a preparation method of the raspberry extract, which includes the following steps:

1) Wash, dry and crush raspberries to obtain raspberry powder;

2) Add an aqueous ethanol solution to the raspberry powder for reflux leaching, and perform suction filtration under reduced pressure to obtain a raspberry leaching solution;

3) The raspberry extract is concentrated under reduced pressure and extracted, and the supernatant is concentrated under reduced pressure and freeze-dried to obtain a raspberry extract; wherein, when 55 g of the raspberry extract is obtained by calculation, the yield is 13.85% and the polysaccharide content is 17.67%.

As a preferred technical solution of the present invention, in step 2), the reflux leaching time is 3-4 hours; the mass concentration of the ethanol aqueous solution is 75%.

As a preferred technical solution of the present invention, in step 2), the dosage ratio of the raspberry powder and ethanol aqueous solution is 1g:10-12mL.

As a preferred technical solution of the present invention, in step 3), the conditions for the reduced pressure concentration are to concentrate at a temperature of 50-60° C. and under reduced pressure until there is no alcohol taste.

As a preferred technical solution of the present invention, in step 3), the extraction conditions are to extract twice with ethyl acetate.

The invention discloses a preparation method of a skin barrier repairing composition containing cryptomeria bud extract. The preparation method of the composition includes the following steps:

(1) Weigh each raw material by weight and set aside;

(2) Add the solvent, cedar bud extract, bougainvillea extract, licorice extract, seaweed extract, raspberry extract and green thorn fruit oil to the blender in sequence, mix, heat, stir, and let stand. That is, a composition for repairing skin barrier containing cryptomeria bud extract is obtained.

As a preferred technical solution of the present invention, in step (2), the heating and stirring conditions are stirring at 30-35°C for 1-1.5 hours; the standing time is 1-2 hours.

As a preferred technical solution of the present invention, the added amount of the skin barrier repairing composition containing cryptomeria bud extract is 5-10% of the total mass of skin care products, and the skin care products include essence, lotion, and toner. , skin base, mask and cream any one.

Beneficial effects of the present invention:

The present invention uses a compound combination of cedar bud extract, Bougainvillea extract, licorice extract, seaweed extract, raspberry extract and green thorn fruit oil to make the composition have antioxidant, moisturizing, moisturizing, improving and repairing properties. The role of the skin barrier.

Detailed ways

In order to further elaborate on the technical means and effects adopted by the present invention to achieve the predetermined inventive purpose, the specific implementation manner, structure, characteristics and effects of the present invention are described in detail below in conjunction with the examples.

Example 1

A skin barrier repairing composition containing cedar bud extract includes the following raw materials in parts by weight: 8 parts of cedar bud extract, 2 parts of Bougainvillea extract, 6 parts of licorice extract, and 1.5 parts of seaweed extract. , 7 parts of raspberry extract, 5 parts of green thorn fruit oil, and 25 parts of solvent.

The solvent is butanediol.

The preparation method of the raspberry extract includes the following steps:

1) Wash, dry and crush raspberries to obtain raspberry powder;

2) Add an ethanol aqueous solution to the raspberry powder for reflux leaching, and filter under reduced pressure to obtain a raspberry leaching solution; wherein the reflux leaching time is 3 hours; the mass concentration of the ethanol aqueous solution is 75%; The dosage ratio of raspberry powder and ethanol aqueous solution is 1g:10mL;

3) The raspberry extract is concentrated and extracted under reduced pressure, and the supernatant is concentrated under reduced pressure and freeze-dried to obtain the raspberry extract; wherein, the conditions for the reduced pressure concentration are at a temperature of 50°C and under reduced pressure. Concentrate under pressure until there is no alcohol smell; the extraction conditions are to extract twice with ethyl acetate.

The preparation method of a skin barrier repairing composition containing cedar bud extract includes the following steps:

(1) Weigh each raw material in parts by weight and set aside;

(2) Add the solvent, cedar bud extract, bougainvillea extract, licorice extract, seaweed extract, raspberry extract and green thorn fruit oil to the blender in sequence, mix, heat, stir, and let stand. That is, a skin barrier repairing composition containing cedar bud extract is obtained; wherein, the heating and stirring conditions are 30° C. and stirring for 1 hour; and the standing time is 1 hour.

Example 2

A skin barrier repairing composition containing cedar bud extract includes the following raw materials in parts by weight: 9 parts of cedar bud extract, 3 parts of Bougainvillea extract, 8 parts of licorice extract, and 1.8 parts of seaweed extract. , 9 parts of raspberry extract, 5.6 parts of green thorn fruit oil, and 28 parts of solvent.

The solvent is butanediol.

The preparation method of the raspberry extract comprises the following steps:

1) washing, drying and crushing raspberries to obtain raspberry powder;

2) Add an ethanol aqueous solution to the raspberry powder for reflux leaching, and filter under reduced pressure to obtain a raspberry leaching solution; wherein the reflux leaching time is 3.2 hours; the mass concentration of the ethanol aqueous solution is 75%; The dosage ratio of the raspberry powder and ethanol aqueous solution is 1g:10.4mL;

3) The raspberry extract is concentrated and extracted under reduced pressure, and the supernatant is concentrated under reduced pressure and freeze-dried to obtain the raspberry extract; wherein, the conditions for the reduced pressure concentration are at a temperature of 52°C and under reduced pressure. Concentrate under pressure until there is no alcohol smell; the extraction conditions are to extract twice with ethyl acetate.

The preparation method of a skin barrier repairing composition containing cedar bud extract includes the following steps:

(1) Weigh each raw material by weight and set aside;

(2) Add a solvent, a Cryptomeria fortunei bud extract, a balsam pear extract, a licorice extract, a seaweed extract, a raspberry extract and a prickle oil into a blender in sequence, mix the mixture, heat and stir, and allow to stand to obtain a composition for repairing the skin barrier containing a Cryptomeria fortunei bud extract; wherein the heating and stirring conditions are at 31° C. and stirring for 1.1 h; and the standing time is 1.2 h.

Example 3

A composition for repairing skin barrier containing cedar bud extract comprises the following raw materials in parts by weight: 10 parts of cedar bud extract, 4 parts of balsam pear extract, 9 parts of liquorice extract, 2.1 parts of seaweed extract, 11 parts of raspberry extract, 6.2 parts of prickle oil and 31 parts of solvent.

The solvent is butanediol.

The preparation method of the raspberry extract includes the following steps:

1) Wash, dry and crush raspberries to obtain raspberry powder;

2) Add an ethanol aqueous solution to the raspberry powder for reflux leaching, and filter under reduced pressure to obtain a raspberry leaching solution; wherein the reflux leaching time is 3.4 hours; the mass concentration of the ethanol aqueous solution is 75%; The dosage ratio of the raspberry powder and ethanol aqueous solution is 1g:10.8mL;

3) The raspberry extract is concentrated and extracted under reduced pressure, and the supernatant is concentrated under reduced pressure and freeze-dried to obtain the raspberry extract; wherein the conditions for the reduced pressure concentration are at a temperature of 54°C and under reduced pressure. Concentrate under pressure until there is no alcohol smell; the extraction conditions are to extract twice with ethyl acetate.

The preparation method of a skin barrier repairing composition containing cedar bud extract includes the following steps:

(1) Weigh each raw material in parts by weight and set aside;

(2) Add the solvent, cedar bud extract, bougainvillea extract, licorice extract, seaweed extract, raspberry extract and green thorn fruit oil to the blender in sequence, mix, heat, stir, and let stand. That is, a skin barrier repairing composition containing cedar bud extract is obtained; wherein, the heating and stirring conditions are 32° C. and stirring for 1.2 hours; and the standing time is 1.4 hours.

Example 4

A composition for repairing skin barrier containing cedar bud extract comprises the following raw materials in parts by weight: 11 parts of cedar bud extract, 5 parts of balsam pear extract, 11 parts of liquorice extract, 2.4 parts of seaweed extract, 12 parts of raspberry extract, 6.8 parts of prickle oil and 34 parts of solvent.

The solvent is butanediol.

The preparation method of the raspberry extract includes the following steps:

1) Wash, dry and crush raspberries to obtain raspberry powder;

2) Add an ethanol aqueous solution to the raspberry powder for reflux leaching, and filter under reduced pressure to obtain a raspberry leaching solution; wherein the reflux leaching time is 3.6 hours; the mass concentration of the ethanol aqueous solution is 75%; The dosage ratio of the raspberry powder and ethanol aqueous solution is 1g:11.2mL;

3) The raspberry extract is concentrated and extracted under reduced pressure, and the supernatant is concentrated under reduced pressure and freeze-dried to obtain the raspberry extract; wherein, the conditions for the reduced pressure concentration are at a temperature of 56°C and under reduced pressure. Concentrate under pressure until there is no alcohol smell; the extraction conditions are to extract twice with ethyl acetate.

The preparation method of a skin barrier repairing composition containing cedar bud extract includes the following steps:

(1) Weigh each raw material in parts by weight and set aside;

(2) Add the solvent, cedar bud extract, bougainvillea extract, licorice extract, seaweed extract, raspberry extract and green thorn fruit oil to the blender in sequence, mix, heat, stir, and let stand. That is, a skin barrier repairing composition containing cedar bud extract is obtained; wherein, the heating and stirring conditions are 33°C and stirring for 1.3 hours; and the standing time is 1.6 hours.

Example 5

A skin barrier repairing composition containing cedar bud extract includes the following raw materials in parts by weight: 12 parts of cedar bud extract, 6 parts of Bougainvillea extract, 12 parts of licorice extract, and 2.7 parts of seaweed extract. , 14 parts of raspberry extract, 7.4 parts of green thorn fruit oil, and 37 parts of solvent.

The solvent is butanediol.

The preparation method of the raspberry extract includes the following steps:

1) Wash, dry and crush raspberries to obtain raspberry powder;

2) Add an ethanol aqueous solution to the raspberry powder for reflux leaching, and perform suction filtration under reduced pressure to obtain a raspberry leaching solution; wherein the reflux leaching time is 3.8 hours; the mass concentration of the ethanol aqueous solution is 75%; The dosage ratio of the raspberry powder and ethanol aqueous solution is 1g:11.6mL;

3) The raspberry extract is concentrated and extracted under reduced pressure, and the supernatant is concentrated under reduced pressure and freeze-dried to obtain the raspberry extract; wherein, the conditions for the reduced pressure concentration are at a temperature of 58°C and under reduced pressure. Concentrate under pressure until there is no alcohol smell; the extraction conditions are to extract twice with ethyl acetate.

The preparation method of a skin barrier repairing composition containing cedar bud extract includes the following steps:

(1) Weigh each raw material in parts by weight and set aside;

(2) Add the solvent, cedar bud extract, bougainvillea extract, licorice extract, seaweed extract, raspberry extract and green thorn fruit oil to the blender in sequence, mix, heat, stir, and let stand. That is, a skin barrier repairing composition containing cedar bud extract is obtained; wherein, the heating and stirring conditions are 34°C and stirring for 1.4 hours; and the standing time is 1.8 hours.

Example 6

A skin barrier repairing composition containing cedar bud extract includes the following raw materials in parts by weight: 13 parts of cedar bud extract, 7 parts of Bougainvillea extract, 14 parts of licorice extract, and 3.0 parts of seaweed extract. , 16 parts of raspberry extract, 8 parts of green thorn fruit oil, and 40 parts of solvent.

The solvent is deionized water.

The preparation method of the raspberry extract includes the following steps:

1) Wash, dry and crush raspberries to obtain raspberry powder;

2) Add an ethanol aqueous solution to the raspberry powder for reflux leaching, and filter under reduced pressure to obtain a raspberry leaching solution; wherein the reflux leaching time is 4 hours; the mass concentration of the ethanol aqueous solution is 75%; The dosage ratio of raspberry powder and ethanol aqueous solution is 1g:12mL;

3) The raspberry extract is concentrated and extracted under reduced pressure, and the supernatant is concentrated under reduced pressure and freeze-dried to obtain the raspberry extract; wherein the conditions for the reduced pressure concentration are at a temperature of 60°C and under reduced pressure. Concentrate under pressure until there is no alcohol smell; the extraction conditions are to extract twice with ethyl acetate.

The preparation method of a skin barrier repairing composition containing cedar bud extract includes the following steps:

(1) Weigh each raw material in parts by weight and set aside;

(2) Add the solvent, cedar bud extract, bougainvillea extract, licorice extract, seaweed extract, raspberry extract and green thorn fruit oil to the blender in sequence, mix, heat, stir, and let stand. That is, a skin barrier repairing composition containing cedar bud extract is obtained; wherein, the heating and stirring conditions are 35°C and stirring for 1.5 hours; and the standing time is 2 hours.

Comparative Examples 1-4

Compared with Example 5, the difference is that the amounts of the Cryptomeria fortunei bud extract, Lablab oleracea extract, Licorice extract and seaweed extract in Comparative Examples 1-4 are as shown in Table 1, and the other components, preparation steps and parameters are the same.

Table 1 (unit: parts by weight)

Cryptomeria fortunei bud extract Bougainvillea Extract Licorice extract seaweed extract Example 5 12 6 12 2.7 Comparative example 1 0 10 16 6.7 Comparative Example 2 14 0 14 4.7 Comparative Example 3 16 10 0 6.7 Comparative example 4 12.9 6.9 12.9 0

Comparative Example 5-7

Compared with Example 5, the difference is that the amounts of seaweed extract, raspberry extract and green thorn fruit oil in Comparative Examples 5-7 are as shown in Table 2, and the remaining components, preparation steps and parameters are the same.

Table 2 (Unit: parts by weight)

Seaweed Extract Raspberry Extract Green thorn fruit oil Cryptomeria bud extract Example 5 2.7 14 7.4 12 Comparative example 5 0 15.35 8.75 12 Comparative example 6 9.7 0 14.4 12 Comparative example 7 6.4 17.7 0 12 Comparative example 8 6.7 18 11.4 0

Test example 1

Determination of the free radical scavenging ability of DPPH. DPPH was prepared into a 2×10 ^-4 mol/L solution with absolute ethanol. The compositions for repairing the skin barrier of Examples 1-6 and the combinations of Comparative Examples 1-4 for repairing the skin barrier. Use the substance as the liquid to be tested. Prepare 2 mL portions of each of the liquid to be tested, absolute ethanol, and DPPH solution. Mix them well and place them at room temperature for 30 minutes. Measure the absorbance at a wavelength of 517 nm to obtain Ai. Each sample is measured three times in parallel. take the average. Use Vc as a positive control, use absolute ethanol instead of DPPH to measure the absorbance value as the control Aj blank, and use DPPH solution and absolute ethanol to mix the absorbance value Ac. Calculate the scavenging rate of DPPH free radicals for each sample to be tested according to the following formula (1), and the results are shown in Table 3;

Clearance rate (%)=(1-(Ai-Aj)/Ac)×100%

table 3

DPPH clearance rate (%) Example 1 84.8 Example 2 82.5 Example 3 76.8 Example 4 79.9 Example 5 84.1 Example 6 77.8 Comparative example 1 58.8 Comparative example 2 62.9 Comparative Example 3 55.2 Comparative example 4 64.2

As can be seen from Table 3, the composition prepared by the present invention has excellent DPPH free radical elimination performance. In detail, it can be seen from Comparative Examples 1-4 that the Cryptomeria fortunei bud extract of the present invention may contain rich flavonoids, such as quercetin, kaempferol, etc., which have strong antioxidant activity and can undergo a single electron transfer reaction with DPPH free radicals, thereby causing the DPPH free radicals to lose their free radical properties; the balsam pear extract may contain polyphenols, such as anthocyanins, etc., which have good free radical scavenging ability and can undergo addition reaction with DPPH free radicals, thereby neutralizing the activity of DPPH free radicals; compounds such as glycyrrhizin and glycyrrhizic acid in the licorice extract also have antioxidant effects, which can reduce the activity of DPPH free radicals by capturing free radicals or inhibiting the generation of free radicals; polysaccharides and polyphenol compounds such as fucoidan and alginate rich in seaweed extracts have also been proven to have antioxidant activity, which can undergo physical adsorption or chemical neutralization reaction with DPPH free radicals, thereby helping to reduce the activity of free radicals; that is, the present invention uses different antioxidant mechanisms, and the four synergistically enhance the DPPH free radical elimination performance of the composition, thereby achieving a stronger antioxidant effect.

Test example 2

100 volunteers with healthy and intact skin aged 25-55 were randomly divided into 10 groups, with 10 people in each group. Use the compositions in Examples 1-6 and Comparative Examples 5-8 once a day in the morning and evening for a cycle of 28 days. Instructions for use: After cleansing every morning and evening, apply an appropriate amount of the composition evenly on the face and massage gently until absorbed.

The transepidermal water loss (TEWL) of the inner side of the forearm was tested using the TM300 tester from the German CK company at week 0 and after continuous use for weeks 2 and 4, i.e. how many grams of water are lost per square meter per hour. TEWL is a very important parameter for evaluating the function of the skin's moisture protection layer. It has been widely recognized internationally and can well reflect the integrity of the skin's barrier function. The standard TEWL is measured when the skin is dry and sweat-free, at an ambient temperature of 24°C and an ambient humidity of 50%. The test data were all obtained under these conditions.

The formula for calculating the TEWL value decrease rate is as follows:

TEWL value decrease rate = (A ₀ -A _n )/A0 × 100%; in the formula, A ₀ is the TEWL value of the 0th week, and A _n is the TEWL value of the nth week.

A positive TEWL value decline rate indicates that the skin barrier has been repaired; conversely, the skin barrier has not been repaired; and the greater the TEWL value decline rate, the better the skin barrier repair effect. The calculation formula for the average decline rate of TEWL value is as follows:

The average decrease rate of TEWL value = the sum of the decrease rate of TEWL value in each group/the number of people in the group;

The results are shown in Table 4.

Table 4

It can be seen from Table 4 that the skin barrier repairing effect of the compositions prepared in Examples 1-6 of the present invention is significantly better than that of Comparative Examples 5-8. This is because the present invention uses raspberry extract and thorn fruit oil. Increase the expression of LOR and K1 genes and promote cell metabolism. Seaweed extract and cedar bud extract can increase the moisture content of the skin and form a protective film, which plays a strengthening role and synergistically achieves the effect of repairing the skin barrier.

The above are only preferred embodiments of the present invention, and do not limit the present invention in any form. Although the present invention has been disclosed above in preferred embodiments, it is not intended to limit the present invention. Anyone skilled in the art , without departing from the scope of the technical solution of the present invention, the technical content disclosed above can be used to make some changes or modifications to equivalent embodiments with equivalent changes. However, without departing from the technical solution content of the present invention, according to the technical solution of the present invention, In essence, any brief modifications, equivalent changes, and modifications made to the above embodiments still fall within the scope of the technical solution of the present invention.

Claims (9)

1. A composition for repairing skin barrier containing a cedar bud extract, which is characterized by comprising the following raw materials in parts by weight: 8-13 parts of Crotalaria sinensis bud extract, 2-7 parts of trifoliate acanthopanax root extract, 6-14 parts of liquorice extract, 1.5-3.0 parts of seaweed extract, 7-16 parts of raspberry extract, 5-8 parts of prinsepia utilis royle oil and 25-40 parts of solvent.

2. A composition for repairing skin barrier comprising a cedar bud extract as in claim 1 wherein the solvent is any of butylene glycol, propylene glycol, and deionized water.

3. A composition for repairing skin barrier comprising a cedar bud extract according to claim 1, wherein the method for preparing the raspberry extract comprises the steps of:

1) Washing, drying and crushing raspberry to obtain raspberry powder;

2) Adding ethanol water solution into raspberry powder for reflux leaching, and performing vacuum suction filtration to obtain raspberry leaching solution;

3) Concentrating under reduced pressure, extracting, collecting supernatant, concentrating under reduced pressure, and lyophilizing to obtain Rubi fructus extract.

4. A composition for repairing skin barrier comprising an extract of cedar sprouts of claim 3 wherein: in the step 2), the reflux leaching time is 3-4h; the mass concentration of the ethanol aqueous solution is 75%.

5. A composition for repairing skin barrier comprising an extract of cedar sprouts of claim 3 wherein: in the step 2), the dosage ratio of the raspberry powder to the ethanol aqueous solution is 1g:10-12mL.

6. A composition for repairing skin barrier comprising an extract of cedar sprouts of claim 3 wherein: in the step 3), the condition of reduced pressure concentration is that the reduced pressure concentration is carried out at the temperature of 50-60 ℃ until no alcohol smell exists.

7. A composition for repairing skin barrier comprising an extract of cedar sprouts of claim 3 wherein: in step 3), the extraction conditions are 2 times of extraction with ethyl acetate.

8. A method of preparing a composition for repairing a skin barrier comprising a cedar bud extract as defined in any of claims 1-7, said method comprising the steps of:

(1) Weighing the raw materials in parts by weight for later use;

(2) Adding solvent, cryptomeria japonica bud extract, acanthopanax trifoliatus extract, glycyrrhrizae radix extract, sargassum extract, rubi fructus extract and Prinsepia utilis royle oil into a stirrer, mixing, heating, stirring, and standing to obtain composition containing Cryptomeria japonica bud extract for repairing skin barrier.

9. A method of preparing a composition for repairing skin barrier comprising a cedar bud extract as defined in claim 8, wherein: in the step (2), the heating and stirring conditions are that stirring is carried out for 1-1.5h at 30-35 ℃; the standing time is 1-2h.