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CN117378803A - A kind of solid atomized oil and preparation method thereof - Google Patents

A kind of solid atomized oil and preparation method thereof Download PDF

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Publication number
CN117378803A
CN117378803A CN202311343147.6A CN202311343147A CN117378803A CN 117378803 A CN117378803 A CN 117378803A CN 202311343147 A CN202311343147 A CN 202311343147A CN 117378803 A CN117378803 A CN 117378803A
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China
Prior art keywords
atomized oil
solid
nicotine
solid atomized
preparation
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202311343147.6A
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Chinese (zh)
Inventor
胡佳伟
王超
王华文
况利平
赵波洋
赵贯云
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dongguan Jichun Biotechnology Co ltd
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Dongguan Jichun Biotechnology Co ltd
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Priority to CN202311343147.6A priority Critical patent/CN117378803A/en
Publication of CN117378803A publication Critical patent/CN117378803A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10Chemical features of tobacco products or tobacco substitutes
    • A24B15/16Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10Chemical features of tobacco products or tobacco substitutes
    • A24B15/16Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A24B15/167Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24FSMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/10Devices using liquid inhalable precursors

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses solid atomized oil and a preparation method thereof, and relates to the technical field of atomized oil. A solid atomized oil comprising, in mass fractions: 4-10% of nicotine salt, 2-7% of higher fatty acid salt and 65-94% of solvent. The solid atomized oil is solid at normal temperature, so that the problem of liquid leakage can be prevented; the components are simple and safe, the health of the human body is not harmful, the sucking taste is good, and the experience of consumers is good; meanwhile, the preparation method is simple and convenient, is easy to operate and can be used for mass production.

Description

Solid atomized oil and preparation method thereof
Technical Field
The invention relates to the technical field of atomized oil, in particular to solid atomized oil and a preparation method thereof.
Background
The aerosol generating device is an electronic delivery device that delivers nicotine to the respiratory system by means of electronic heating. As a substitute for nicotine products, it has nicotine taste, but no ash, no cigarette end, no combustion, no open fire, and no harmful substances such as tar, carbon monoxide, hydrocyanic acid, acrolein, arsenic, lead, mercury, etc. In addition, the nicotine solution is atomized to form aerosol, and the aerosol is diluted rapidly in air without forming second hand smoke. The electronic aerosol generating device integrates modern microelectronic technology, biotechnology and healthy living concept, and attracts many eyeballs of consumers who want to abstain from nicotine in a short time.
Because of the numerous advantages of electronic aerosol generating devices, an increasing number of consumers are beginning to accept and use, and some of the disadvantages of electronic aerosol generating devices are also increasingly manifested. According to investigation, the current commercial electronic aerosol generating devices mostly use nicotine atomized liquid with better fluidity, but liquid leakage is easy to occur from the positions of the atomizer base, the joint of the oil bin and the base, the suction nozzle and the like. Although the structure of the atomizer is continuously improved by the existing manufacturer, a closed atomizer is developed, the problem of liquid leakage in the product transportation process is well solved by adopting a blocking type design of an airflow channel and a smoke liquid channel, once the product is used, the airflow channel and the smoke liquid channel are always communicated, the situation of liquid leakage still inevitably occurs in the later use process, the consumer generates bad sucking experience, the quality of an electronic aerosol generating device is directly influenced by the problems, and meanwhile, the development of the electronic aerosol generating device is restrained.
In this regard, there are studies on solid atomized oil (solid atomized oil) by existing manufacturers, for example, chinese patent application CN114271532a discloses a solid atomized oil containing tamarind seed polysaccharide and a preparation method thereof, wherein polyhydroxy groups of tamarind seed polysaccharide and hydroxyl groups of a polyol are combined, and the polyol is solidified into gel without fluidity after dehydration, so as to form the solid atomized oil. The Chinese patent application with the patent number of CN110150725A discloses solid atomized oil, a preparation method and application thereof, and the solid atomized oil is obtained by mixing a porous carrier, a thickening agent, a binder and an atomizing agent. However, most of the polysaccharide components and the thickener binder used in the solid atomized liquid prepared by the two techniques are macromolecular components, and the risk of core pasting is caused in the atomization process of the atomized liquid, so that bad consumption experience can be brought to consumers.
Meanwhile, some manufacturers prepare solid atomized oil products, and vitamin E esters are used as emulsifying agents for realizing solidification of the atomized oil, so that the homogenization problem of the electronic atomized oil, essence, perfume and atomizing agents is solved, but reports show that a large amount of substances which block lung tissue structures and are found in the lungs of some atomized electronic cigarette deaths are related to vitamin E esters which are additives in the electronic atomized oil.
Therefore, research on solid atomized oil is urgently needed, the problem that atomized liquid is easy to leak in an electronic aerosol generating device can be solved, meanwhile, the components are simple and safe, damage to human health can be avoided, the taste is improved, and the experience of consumers is improved.
Disclosure of Invention
The invention aims to solve the technical problems that the existing electronic aerosol generating device is easy to leak liquid, the use experience of consumers is poor, the solid atomized oil is complex in component, the cost is high, and the components which are unfavorable to the health of human bodies can be contained.
In order to solve the technical problems, the aim of the invention is realized by the following technical scheme: the solid atomized oil is solid at normal temperature, so that the problem of liquid leakage can be prevented; the components are simple and safe, the health of the human body is not harmful, the sucking taste is good, and the experience of consumers is good; meanwhile, the preparation method is simple and convenient, is easy to operate and can be used for mass production.
Specifically, the invention discloses solid atomized oil, which comprises the following components in percentage by mass: 4-10% of nicotine salt, 2-7% of higher fatty acid salt and 65-94% of solvent.
Preferably, the nicotine salt is nicotine benzoate, and the molar ratio of nicotine to benzoic acid is 1:0.9-1.5.
Preferably, the nicotine benzoate comprises 15-25wt% of nicotine.
Preferably, the higher fatty acid salt is at least one of sodium stearate, sodium palmitate, sodium myristate and sodium laurate.
Preferably, the solvent is a mixture of glycerol and propylene glycol, and the mass ratio of the glycerol to the propylene glycol is 0.4-2.0:1.
preferably, the mass ratio of the higher fatty acid salt to the dissolved glycerol is 1:5-30.
Preferably, the composition further comprises essence and/or perfume, wherein the content of the essence or perfume is 0.1-5.0wt%.
Preferably, the nicotine salt is present in an amount of 4-8%.
The invention also discloses a preparation method of the solid atomized oil, which comprises the steps of adding higher fatty acid salt into the heated solvent, cooling, adding nicotine salt, and stirring and uniformly mixing to obtain the solid atomized oil.
Preferably, the heating is to 110-125 ℃, and the cooling is to 75-85 ℃.
The beneficial effects are that:
the solid atomized oil is solid at normal temperature, is converted into liquid after being heated to a certain temperature, is converted into gas after being raised to a certain temperature, is convenient to use, and can avoid the phenomenon of liquid leakage to the greatest extent; meanwhile, the high-grade fatty acid is adopted as the hardener, the curing efficiency is high, the solvent can be cured after the small dose is mixed with the solvent, no residue is reserved after heating, the suction sensory quality is not affected, the suction taste is good, the consumer experience is good, the components are simple, the damage to the human health is avoided, and the method is safe and reliable. Meanwhile, the preparation process of the solid atomized oil is simple and convenient, is easy to operate, and can realize large-scale mass production.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for the description of the embodiments will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic view of a solid atomized oil prepared in example 1 of the present invention;
FIG. 2 is a schematic diagram of the solid atomized oil prepared in comparative example 1.
Detailed Description
The technical solutions of the present invention will be clearly and completely described in conjunction with the embodiments of the present invention, and it is apparent that the described embodiments are some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
It should be understood that the terms "comprises" and "comprising," when used in this specification and the appended claims, specify the presence of stated features, integers, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and/or groups thereof.
It is also to be understood that the terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used in this specification and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise.
It should be further understood that the term "and/or" as used in the present specification and the appended claims refers to any and all possible combinations of one or more of the associated listed items, and includes such combinations.
For the purpose of making the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is apparent that the described embodiments are some embodiments of the present invention, but not all embodiments of the present invention. The components of the embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the invention, as presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
A solid atomized oil comprising, in mass fractions: 4-10% of nicotine salt, 2-7% of higher fatty acid salt and 65-94% of solvent.
The content of nicotine salt is preferably 4-8%, and the content of higher fatty acid salt is preferably 2-6%.
The nicotine salt is selected from nicotine benzoate, and the molar ratio of nicotine to benzoic acid is 1:0.9-1.5. The nicotine content is preferably 15-25wt%, more preferably 20wt%.
The higher fatty acid salt is at least one selected from sodium stearate, sodium palmitate, sodium myristate and sodium laurate.
The solvent is preferably a mixture of glycerol and propylene glycol, and the mass ratio of the glycerol to the propylene glycol is 0.4-2.0:1.
in order to improve the curing efficiency, the mass ratio of the higher fatty acid salt to the dissolved glycerin is preferably 1:5-30.
Essence and/or perfume may also be added to adjust the suction taste of the solid atomized oil, wherein the content of essence or perfume is 0.1-5.0wt%.
Specifically, the solid atomized oil takes nicotine salt as a nicotine source, so that a consumer achieves the aim of addiction elimination; the glycerol can be taken as a solvent to be absorbed by higher fatty acid salt to form solid, and meanwhile, the glycerol and the propylene glycol are taken as an atomizing agent, so that a good atomizing effect can be generated; the higher fatty acid salt is used as a hardening agent, the solvent is absorbed after heating and dissolving, and the solid atomized oil can be formed after cooling; the flavour and/or fragrances act to modulate the taste, resulting in a more pleasant smoking experience. The prepared solid atomized oil is uniform and stable, so that nicotine salt can be uniformly distributed in the atomized oil, overlarge taste deviation caused by uneven atomization of the nicotine salt is avoided, and larger suction atomization amount can be obtained.
The mass ratio of the glycerol to the propylene glycol can influence the atomization effect of the glycerol and the propylene glycol, so that the use feeling of consumers is influenced; meanwhile, the mass ratio of the higher fatty acid salt to the solvent can influence the curing efficiency, the curing state and the atomization amount of the higher fatty acid salt, and the preparation process is influenced, if the content of the higher fatty acid salt is too high, the hardness after curing is too high, the taste is influenced, the use experience of consumers is reduced, meanwhile, the cost is increased, and if the content of the higher fatty acid salt is too low, the curing efficiency is poor, and the good curing effect and the good curing state are not achieved.
According to the preparation method of the solid atomized oil, the higher fatty acid salt is added into the heated solvent, the nicotine salt is added after the temperature is reduced, and the solid atomized oil is obtained after stirring and mixing.
The heating is heating to 110-125 ℃, and the cooling is cooling to 75-85 ℃. Wherein the temperature of 110-125 ℃ is dissolution temperature, and the temperature of 75-85 ℃ is heat preservation temperature.
Specifically, the method comprises the following steps:
s1, preparing atomized oil: uniformly mixing a solvent (glycerin and propylene glycol), heating to 110-125 ℃, adding higher fatty acid salt, stirring and dissolving to form a mixed solution, cooling to 75-85 ℃, preserving heat, adding nicotine salt, adding essence and/or essence with different tastes according to different taste requirements, preserving heat at 75-85 ℃, stirring and uniformly mixing to form atomized oil with different tastes;
s2, casting and forming: pouring the prepared atomized oil into a mould while the atomized oil is hot, and cooling and solidifying at room temperature (25-30 ℃) to obtain the solid atomized oil. If no special shape is needed, the solid atomized oil can be obtained by direct cooling.
Wherein, the nicotine salt, essence and/or essence are added when the temperature is reduced to 75-85 ℃, so that the nicotine salt and essence are not destroyed by high temperature, the stability of the nicotine salt and essence is ensured, and the mixed solution is ensured to be kept in a liquid state.
Example 1
A solid atomized oil comprising the following components: nicotine salt (5 g), sodium stearate (3 g), glycerin (38 g), propylene glycol (52 g), tobacco flavor (1.8 g), peppermint essence (0.2 g).
Wherein, in the nicotine salt, the content of nicotine is 20wt%, and the molar ratio of nicotine to benzoic acid is 1:1.2.
The preparation method of the solid atomized oil comprises the following steps:
s1, preparing atomized oil: mixing 38g of glycerol and 52g of propylene glycol uniformly, heating to 120 ℃, adding 3g of sodium stearate, stirring and dissolving to form a mixed solution, cooling to 80 ℃ and preserving heat, adding 5g of nicotine salt, 1.8g of tobacco flavor and 0.2g of mint essence into the mixed solution, preserving heat at 80 ℃, stirring and mixing uniformly to form atomized oil with mint tobacco taste;
s2, casting and forming: pouring the prepared atomized oil into a mould while the atomized oil is hot, and cooling and solidifying at room temperature (25-30 ℃) to obtain the solid atomized oil. As shown in fig. 1.
Examples 2 to 6
The solid atomized oil differs from example 1 in that: the mass of each component in the solid atomized oil was different, as shown in table 1 below.
Table 1 solid atomized oil components of examples 1-6
Examples 7 to 11
The solid atomized oil differs from example 1 in that: the process for preparing atomized oil in S1 is different and is specifically shown in Table 2 below.
TABLE 2 Process parameters for example 1, examples 7-11
Comparative examples 1 to 4
The solid atomized oil differs from example 1 in that: the mass of each component in the solid atomized oil was different, as shown in table 3 below.
Table 3 solid atomized oil components of comparative examples 1 to 4
Comparative example 1 a solid atomized oil was prepared. As shown in fig. 2.
Comparative examples 5 to 10
The solid atomized oil differs from example 1 in that: the process for preparing atomized oil in S1 is different and is specifically shown in Table 4 below.
Table 4 Process parameters of comparative examples 5-10
Performance test:
after the preparation of the solid atomized oil, the solid atomized oil is stored at room temperature for 3 days to be sampled, and 20 professional sensory evaluators (after atomization of the atomized oil) are selected to evaluate the atomized oil samples respectively, wherein the evaluation items are shown in table 5, and the evaluation results are shown in table 6.
TABLE 5 sensory evaluation index
Table 6 sensory evaluation of examples 1-11 and comparative examples 1-12 stored for 3 days
In combination with the sensory evaluation conditions of example 1 and examples 2-11 and in combination with tables 5 and 6, it can be seen that the solid atomized oil has better solidification effect within the technological parameters of the preparation method of the solid atomized oil, and the solidified atomized oil has smaller influence on the fragrance base after being heated and liquefied again, rich taste and layering, and light impurity taste and pure taste.
In combination with the sensory evaluation of examples 1 and comparative examples 1 to 4 at the completion of the preparation of the solid atomized oil, and with reference to tables 5 and 6, it can be seen that comparative examples 1 to 4 show that when glycerin or sodium stearate is used in an amount lower than the preparation amount, the solid atomized oil is not easily solidified, and the solidification effect is better than that in the preparation amount, but the hardness is too great, and the liquefying effect after heating is poor, and the taste after atomization is greatly affected.
In combination with the sensory evaluation cases of example 1 and comparative examples 5 to 10 at the completion of the preparation, and in combination with tables 5 and 6, it can be seen that when the dissolution temperature is too low, sodium stearate is not easily dissolved, the solid atomized oil is not easily solidified, and when the dissolution temperature is too high, glycerin is polymerized, so that the taste of the solid atomized oil is affected; when the heat preservation temperature is too low, the fluidity of the solid atomized oil is poor, injection molding is difficult, and when the heat preservation temperature is too high, nicotine salt and essence are easily destroyed, so that the taste of the solid atomized oil is affected.
While the invention has been described with reference to certain preferred embodiments, it will be understood by those skilled in the art that various changes and substitutions of equivalents may be made and equivalents will be apparent to those skilled in the art without departing from the scope of the invention. Therefore, the protection scope of the invention is subject to the protection scope of the claims.

Claims (10)

1.一种固体雾化油,其特征在于,按质量分数计,包含以下成分:尼古丁盐4-10%,高级脂肪酸盐2-7%,溶剂65-94%。1. A solid atomized oil, characterized in that it contains the following ingredients in terms of mass fraction: 4-10% of nicotine salts, 2-7% of higher fatty acid salts, and 65-94% of solvents. 2.根据权利要求1所述的固体雾化油,其特征在于,所述尼古丁盐为尼古丁苯甲酸盐,尼古丁与苯甲酸的摩尔比为1:0.9-1.5。2. The solid atomized oil according to claim 1, characterized in that the nicotine salt is nicotine benzoate, and the molar ratio of nicotine to benzoic acid is 1:0.9-1.5. 3.根据权利要求2所述的固体雾化油,其特征在于,所述尼古丁苯甲酸盐中,尼古丁的含量为15-25wt%。3. The solid atomized oil according to claim 2, characterized in that the content of nicotine in the nicotine benzoate is 15-25wt%. 4.根据权利要求1所述的固体雾化油,其特征在于,所述高级脂肪酸盐为硬脂酸钠、棕榈酸钠、肉豆蔻酸钠、月桂酸钠中的至少一种。4. The solid atomized oil according to claim 1, characterized in that the higher fatty acid salt is at least one of sodium stearate, sodium palmitate, sodium myristate and sodium laurate. 5.根据权利要求1所述的固体雾化油,其特征在于,所述溶剂为甘油和丙二醇的混合物,甘油和丙二醇的质量比为0.4-2.0:1。5. The solid atomized oil according to claim 1, characterized in that the solvent is a mixture of glycerin and propylene glycol, and the mass ratio of glycerol and propylene glycol is 0.4-2.0:1. 6.根据权利要求5所述的固体雾化油,其特征在于,所述高级脂肪酸盐与溶甘油的质量比为1:5-30。6. The solid atomized oil according to claim 5, characterized in that the mass ratio of the higher fatty acid salt to dissolved glycerin is 1:5-30. 7.根据权利要求1所述的固体雾化油,其特征在于,还包括香精、和/或香料,所述香精或香料的含量为0.1-5.0wt%。7. The solid atomized oil according to claim 1, characterized in that it also includes essence and/or fragrance, and the content of the essence or fragrance is 0.1-5.0wt%. 8.根据权利要求1所述的固体雾化油,其特征在于,所述尼古丁盐的含量为4-8%。8. The solid atomized oil according to claim 1, characterized in that the content of the nicotine salt is 4-8%. 9.根据权利要求1-8任意一项所述的固体雾化油的制备方法,其特征在于,在加热后的溶剂中加入高级脂肪酸盐,降温后加入尼古丁盐,搅拌混匀,得到固体雾化油。9. The preparation method of solid atomized oil according to any one of claims 1 to 8, characterized in that, adding higher fatty acid salts to the heated solvent, adding nicotine salt after cooling, and stirring and mixing to obtain a solid Atomized oil. 10.根据权利要求9所述的固体雾化油的制备方法,其特征在于,所述加热为加热至110-125℃,所述降温为降温至75-85℃。10. The preparation method of solid atomized oil according to claim 9, characterized in that the heating is heating to 110-125°C, and the cooling is cooling to 75-85°C.
CN202311343147.6A 2023-10-17 2023-10-17 A kind of solid atomized oil and preparation method thereof Pending CN117378803A (en)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017089931A1 (en) * 2015-11-25 2017-06-01 R. J. Reynolds Tobacco Company Nicotine salts, co-crystals, and salt co-crystal complexes
CN113164610A (en) * 2018-12-28 2021-07-23 菲利普莫里斯生产公司 Liquid nicotine formulation comprising a low molar mass metal salt
CN113163844A (en) * 2018-12-28 2021-07-23 菲利普莫里斯生产公司 High viscosity nicotine formulations
CN113423290A (en) * 2018-12-28 2021-09-21 菲利普莫里斯生产公司 Nicotine formulations comprising metal salts
US20220152013A1 (en) * 2020-11-16 2022-05-19 Fertin Pharma A/S Solid oral nicotine formulation
US20220232890A1 (en) * 2019-10-24 2022-07-28 Nerudia Limited Smoking substitute system
CN114945287A (en) * 2019-12-18 2022-08-26 菲利普莫里斯生产公司 Formulations for aerosol-generating systems

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017089931A1 (en) * 2015-11-25 2017-06-01 R. J. Reynolds Tobacco Company Nicotine salts, co-crystals, and salt co-crystal complexes
CN113164610A (en) * 2018-12-28 2021-07-23 菲利普莫里斯生产公司 Liquid nicotine formulation comprising a low molar mass metal salt
CN113163844A (en) * 2018-12-28 2021-07-23 菲利普莫里斯生产公司 High viscosity nicotine formulations
CN113423290A (en) * 2018-12-28 2021-09-21 菲利普莫里斯生产公司 Nicotine formulations comprising metal salts
US20220232890A1 (en) * 2019-10-24 2022-07-28 Nerudia Limited Smoking substitute system
CN114945287A (en) * 2019-12-18 2022-08-26 菲利普莫里斯生产公司 Formulations for aerosol-generating systems
US20220152013A1 (en) * 2020-11-16 2022-05-19 Fertin Pharma A/S Solid oral nicotine formulation

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Application publication date: 20240112