CN117194999A - Radiotherapy plan similarity determination method, device, electronic equipment and storage medium - Google Patents

Abstract

The application discloses a method, a device, electronic equipment and a storage medium for determining similarity of a radiotherapy plan. Wherein the method comprises the following steps: acquiring first characteristics corresponding to a first radiotherapy plan, wherein the first characteristics are used for representing distance information from each radioactive source to each first organ in N first organs in portal information formulated by the first radiotherapy plan; acquiring second characteristics corresponding to a second radiotherapy plan, wherein the second characteristics are used for representing distance information from each radioactive source to each second organ in M second organs in portal information formulated by the second radiotherapy plan; and determining the similarity of the first radiotherapy plan and the second radiotherapy plan according to the first characteristic and the second characteristic. The application solves the technical problem that the similarity determination of the radiotherapy plan is inaccurate caused by comparing the similarity of the radiotherapy plan according to the image characteristics in the prior art.

Description

Radiotherapy plan similarity determination method, device, electronic equipment and storage medium

Technical field

This application relates to the field of medical technology, specifically, to a method, device, electronic equipment and storage medium for determining the similarity of radiotherapy plans.

Background technique

In the field of medical technology, especially in the field of radiotherapy technology, it is often necessary to compare the similarity of two radiotherapy plans. For example, when evaluating a target radiotherapy plan corresponding to a target object, it is necessary to compare the history of the target radiotherapy plan and the target object. Similarity of radiotherapy plans.

However, in the prior art, when comparing the similarity of radiotherapy plans, the comparison is usually only based on the image features of the medical images corresponding to the radiotherapy plans, with less reference dimensions and reference information, resulting in inaccurate determination of the similarity of radiotherapy plans. The problem.

In response to the above problems, no effective solution has yet been proposed.

Contents of the invention

This application provides a method, device, electronic device and storage medium for determining the similarity of radiotherapy plans, to at least solve the problem of radiotherapy plans that are only compared based on image features in the prior art when comparing the similarities of radiotherapy plans. The technical problem of inaccurate determination of similarity.

According to one aspect of the present application, a method for determining the similarity of radiotherapy plans is provided, including: obtaining a first feature corresponding to the first radiotherapy plan, wherein the first feature is used to characterize the radiation field information formulated in the first radiotherapy plan The distance information from each radiation source in to each of the N first organs, the N first organs including the radiotherapy target area of the radiotherapy subject corresponding to the first radiotherapy plan and at least one organ at risk; obtain the second The second feature corresponding to the radiotherapy plan, where the second feature is used to characterize the distance information from each radiation source to each of the M second organs in the radiation field information formulated in the second radiotherapy plan, M The second organ includes a radiotherapy target area of the radiotherapy subject corresponding to the second radiotherapy plan and at least one organ at risk; the similarity between the first radiotherapy plan and the second radiotherapy plan is determined based on the first feature and the second feature.

Optionally, the method for determining the similarity of the radiotherapy plan further includes: obtaining a third feature corresponding to the first radiotherapy plan, where the third feature is an overlapping volume from each radiation source in the first radiotherapy plan to the N first organs. Histogram information; obtain the fourth feature corresponding to the second radiotherapy plan, where the fourth feature is the overlapping volume histogram information from each radiation source to the M second organs in the second radiotherapy plan; according to the first feature, the The second feature, the third feature and the fourth feature determine the similarity between the first radiotherapy plan and the second radiotherapy plan.

Optionally, the method for determining the similarity of the radiotherapy plan further includes: generating a first curve corresponding to the first radiotherapy plan based on the first feature and the third feature, where the first curve is with the first feature as the abscissa, the third feature is a curve formed by the ordinate; a second curve corresponding to the second radiotherapy plan is generated based on the second feature and the fourth feature, where the second curve is formed by taking the second feature as the abscissa and the fourth feature as the ordinate. Curve; determine the similarity between the first radiotherapy plan and the second radiotherapy plan based on the first curve and the second curve.

Optionally, the method for determining the similarity of the radiotherapy plan also includes: displaying the first curve and the second curve on the same coordinate system, and calculating the area of the graph composed of the first curve and the second curve on the same coordinate system; according to The area of the graph determines the similarity between the first radiotherapy plan and the second radiotherapy plan, where there is a negative correlation between the area of the graph and the similarity.

Optionally, the method for determining the similarity of radiotherapy plans also includes: obtaining the position coordinates of each radiation source in the first radiotherapy plan in a resampling coordinate system, where the resampling coordinate system is used for Expand the horizontal plane size on the basis of the medical image; determine the first feature according to the position coordinates and the delineation information corresponding to the first radiotherapy plan, where the delineation information is used to characterize each of the N first organs in the first radiotherapy plan. Contour information in medical images.

Optionally, the method for determining the similarity of radiotherapy plans also includes: obtaining the field angle and source axis distance corresponding to each radiation source in the first radiotherapy plan, where the source axis distance corresponding to each radiation source is used to characterize the The distance between the radiation source and the rotation axis of the gantry; determine the position coordinates of each radiation source in the first radiation therapy plan in the resampled coordinate system based on the field angle and source axis distance corresponding to each radiation source in the first radiation therapy plan .

Optionally, the method for determining the similarity of radiotherapy plans further includes: obtaining the position coordinates of each radiation source in the first radiotherapy plan on a first horizontal plane, where the first horizontal plane is the coordinates of the radiotherapy object corresponding to the first radiotherapy plan. The horizontal plane with the radiotherapy target area as the center point; the first radiotherapy plan is determined based on the position coordinates of each radioactive source in the first radiotherapy plan on the first horizontal plane, the field angle corresponding to each radioactive source in the first radiotherapy plan, and the source axis distance. The position coordinates of each radiation source in the radiotherapy plan in the resampled coordinate system.

According to another aspect of the present application, a radiotherapy plan similarity determination device is also provided, including: a first acquisition unit, configured to obtain a first feature corresponding to the first radiotherapy plan, wherein the first feature is used to characterize the The distance information from each radiation source in the radiation field information formulated in the first radiotherapy plan to each of the N first organs. The N first organs include the radiotherapy target area of the radiotherapy object corresponding to the first radiotherapy plan. and at least one organ at risk; a second acquisition unit, used to acquire a second feature corresponding to the second radiotherapy plan, wherein the second feature is used to characterize each radiation source to M in the radiation field information formulated in the second radiotherapy plan distance information of each of the second organs, the M second organs including the radiotherapy target area of the radiotherapy subject corresponding to the second radiotherapy plan and at least one organ at risk; the determination unit is configured to determine based on the first characteristic and the first The two features determine the similarity between the first radiotherapy plan and the second radiotherapy plan.

According to another aspect of the present application, a computer-readable storage medium is also provided, wherein the computer-readable storage medium stores a computer program, wherein when the computer program is running, the device where the computer-readable storage medium is located is controlled to execute any of the above. A method for determining the similarity of radiotherapy plans.

According to another aspect of the present application, an electronic device is also provided, wherein the electronic device includes one or more processors and a memory, and the memory is used to store one or more programs, wherein when one or more programs are processed by a When executed by or multiple processors, one or more processors implement any one of the above radiotherapy plan similarity determination methods.

In this application, the similarity of the radiotherapy plan is determined based on the distance information from the radioactive source to the radiotherapy target area and the organs at risk. First, the first feature corresponding to the first radiotherapy plan and the second feature corresponding to the second radiotherapy plan are obtained. features, and then determine the similarity between the first radiotherapy plan and the second radiotherapy plan based on the first feature and the second feature. Wherein, the first feature is used to characterize the distance information from each radiation source in the radiation field information formulated in the first radiotherapy plan to each of the N first organs, and the N first organs include the first radiotherapy The radiotherapy target area and at least one risk organ of the radiotherapy subject corresponding to the plan; the second feature is used to characterize each radiation source in the radiation field information formulated in the second radiotherapy plan to each of the M second organs. Based on the distance information, the M second organs include the radiotherapy target area of the radiotherapy subject corresponding to the second radiotherapy plan and at least one organ at risk.

It can be seen from the above that, unlike the prior art method of determining the similarity of radiotherapy plans only through image features corresponding to the radiotherapy plans, this application determines the similarity of radiotherapy plans based on distance information from the radioactive source to the radiotherapy target area and organs at risk. degree, as a comparison, image features can usually only represent the outline information of the radiotherapy target area and organs at risk, but cannot represent other information, while the distance information from the radiation source to the radiotherapy target area and organs at risk can represent both the radiation field information and the organ at risk. The relative positional relationship between the radiotherapy source, the radiotherapy target area and the organs at risk. At the same time, because the distance information corresponding to the radiotherapy target area and/or the organs at risk and the radioactive source will be different with different shapes, therefore, the distance from the radiotherapy source to the radiotherapy target The distance information between the area and the organs at risk can actually represent the shape information of the radiotherapy target area and the organs at risk.

It can be seen that compared with the existing technology, the technical solution of the present application can determine the similarity of the radiotherapy plan from more reference dimensions, thereby improving the accuracy of determining the similarity of the radiotherapy plan, thereby solving the problem of comparison in the existing technology. When determining the similarity of radiotherapy plans, comparisons are made only based on image features, which leads to inaccurate technical problems in determining the similarity of radiotherapy plans.

Description of the drawings

The drawings described here are used to provide a further understanding of the present application and constitute a part of the present application. The illustrative embodiments of the present application and their descriptions are used to explain the present application and do not constitute an improper limitation of the present application. In the attached picture:

Figure 1 is a flow chart of an optional radiotherapy plan similarity determination method according to an embodiment of the present application;

Figure 2 is a schematic diagram of an optional curve generated based on distance information and overlapping volume histogram information according to an embodiment of the present application;

Figure 3 is a schematic diagram of a graph composed of an optional first curve and a second curve according to an embodiment of the present application;

Figure 4 is an optional flow chart for determining the position coordinates of each radiation source in the first radiation therapy plan in the resampled coordinate system according to an embodiment of the present application;

Figure 5 is an optional distance distribution diagram according to an embodiment of the present application;

Figure 6 is a schematic diagram of a process for determining the similarity of radiotherapy plans according to an embodiment of the present application;

Figure 7 is a schematic diagram of an optional radiotherapy plan similarity determination device according to an embodiment of the present application.

Detailed ways

In order to enable those in the technical field to better understand the solutions of the present application, the technical solutions in the embodiments of the present application will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present application. Obviously, the described embodiments are only These are part of the embodiments of this application, not all of them. Based on the embodiments in this application, all other embodiments obtained by those of ordinary skill in the art without creative efforts should fall within the scope of protection of this application.

It should be noted that the terms "first", "second", etc. in the description and claims of this application and the above-mentioned drawings are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It is to be understood that the data so used are interchangeable under appropriate circumstances so that the embodiments of the application described herein can be practiced in sequences other than those illustrated or described herein. In addition, the terms "including" and "having" and any variations thereof are intended to cover non-exclusive inclusions, e.g., a process, method, system, product, or apparatus that encompasses a series of steps or units and need not be limited to those explicitly listed. Those steps or elements may instead include other steps or elements not expressly listed or inherent to the process, method, product or apparatus.

It should also be noted that the relevant information (including but not limited to patient information, etc.) and data (including but not limited to data for display and analysis, etc.) involved in this application are all authorized by the user or obtained by all parties. Fully authorized information and data. For example, there is an interface between this system and relevant users or institutions. Before obtaining relevant information, it is necessary to send an acquisition request to the aforementioned users or institutions through the interface, and after receiving the consent information fed back by the aforementioned users or institutions, obtain the relevant information. information.

The present application will be further described below in conjunction with each embodiment.

Example 1

According to the embodiment of the present application, an embodiment of a method for determining the similarity of radiotherapy plans is provided. It should be noted that the steps shown in the flow chart of the accompanying drawings can be executed in a computer system such as a set of computer-executable instructions. , and, although a logical order is shown in the flowchart diagrams, in some cases the steps shown or described may be performed in an order different from that herein.

Figure 1 is a flow chart of an optional radiotherapy plan similarity determination method according to an embodiment of the present application. As shown in Figure 1, the method includes the following steps:

Step S101: Obtain the first feature corresponding to the first radiotherapy plan.

In step S101, the first feature is used to characterize the distance information from each radiation source in the radiation field information formulated in the first radiotherapy plan to each of the N first organs, and the N first organs include The radiotherapy target area and at least one organ at risk of the radiotherapy subject corresponding to the first radiotherapy plan.

Optionally, the radiation field information formulated in the first radiotherapy plan includes at least one radioactive source. It is assumed that the radioactive field information formulated in the first radiotherapy plan includes two radioactive sources, namely radioactive source A and radioactive source B. The first radiotherapy source The radiotherapy target volume of the radiotherapy subject corresponding to the plan is target volume PTV1, and at least one organ at risk of the radiotherapy subject corresponding to the first radiotherapy plan is OAR1 and OAR2 respectively. On this basis, the first feature corresponding to the first radiotherapy plan is used to represent the distance information of radioactive source A to the target areas PTV1, OAR1, and OAR2 respectively, and the distance information of radioactive source B to the target areas PTV1, OAR1, and OAR2 respectively.

Step S102: Obtain the second feature corresponding to the second radiotherapy plan.

In step S102, the second feature is used to characterize the distance information from each radiation source in the radiation field information formulated in the second radiotherapy plan to each of the M second organs, and the M second organs include The radiotherapy target area and at least one organ at risk of the radiotherapy subject corresponding to the second radiotherapy plan.

Optionally, the radiotherapy subject corresponding to the first radiotherapy plan and the radiotherapy subject corresponding to the second radiotherapy plan may be the same subject, or they may be different subjects. In addition, the radiation field information formulated in the second radiotherapy plan includes at least one radioactive source. For example, assume that the radioactive field information formulated in the second radiotherapy plan also includes two radioactive sources, namely radioactive source C and radioactive source D. The radiotherapy target volume of the radiotherapy subject corresponding to the second radiotherapy plan is target volume PTV2, and at least one organ at risk of the radiotherapy subject corresponding to the second radiotherapy plan is OAR3 and OAR4 respectively. On this basis, the second feature corresponding to the second radiotherapy plan is used to characterize the distance information of the radioactive source C to the target areas PTV2, OAR3, and OAR4 respectively, and the distance information of the radioactive source D to the target areas PTV2, OAR3, and OAR4 respectively.

Step S103: Determine the similarity between the first radiotherapy plan and the second radiotherapy plan based on the first feature and the second feature.

Optionally, since both the first feature and the second feature represent distance information from the radiation source to the radiotherapy target area and the organs at risk, comparing the similarity between the first feature and the second feature is to compare the first radiotherapy plan and the The similarity of the distance information from the respective radioactive sources to the radiotherapy target area and organs at risk in the second radiotherapy plan. If the similarity between the first feature and the second feature is high, it indicates the similarity between the first radiotherapy plan and the second radiotherapy plan. higher.

Based on the above steps S101 to S103, it can be seen that in this application, the similarity of the radiotherapy plan is determined based on the distance information from the radioactive source to the radiotherapy target area and the organs at risk. First, the third radiotherapy plan corresponding to the first radiotherapy plan is obtained. A feature corresponds to a second feature of the second radiotherapy plan, and then, the similarity between the first radiotherapy plan and the second radiotherapy plan is determined based on the first feature and the second feature. Wherein, the first feature is used to characterize the distance information from each radiation source in the radiation field information formulated in the first radiotherapy plan to each of the N first organs, and the N first organs include the first radiotherapy The radiotherapy target area and at least one risk organ of the radiotherapy subject corresponding to the plan; the second feature is used to characterize each radiation source in the radiation field information formulated in the second radiotherapy plan to each of the M second organs. Based on the distance information, the M second organs include the radiotherapy target area of the radiotherapy subject corresponding to the second radiotherapy plan and at least one organ at risk.

It can be seen from the above that, unlike the prior art method of determining the similarity of radiotherapy plans only through image features corresponding to the radiotherapy plans, this application determines the similarity of radiotherapy plans based on distance information from the radioactive source to the radiotherapy target area and organs at risk. degree, because image features can usually only represent the outline information of the radiotherapy target area and organs at risk, and cannot represent other information, while the distance information from the radiation source to the radiotherapy target area and organs at risk can represent not only the radiation field information, but also the radiation source. The relative positional relationship between the radiation therapy target area and the organs at risk. In addition, since the distance information corresponding to the radiotherapy target area and the organs at risk of different shapes and the radiation source will be different, therefore, the distance information from the radiation source to the radiotherapy target area and the organs at risk will be different. The distance information of The similarity of radiotherapy plans determines the accuracy, thus solving the technical problem in the prior art that when comparing the similarities of radiotherapy plans, the comparison is only based on image features, resulting in inaccurate determination of the similarity of radiotherapy plans.

In an optional embodiment, a radiotherapy plan similarity determination device can be used as the execution subject of the radiotherapy plan similarity determination method in the embodiment of the present application, wherein the radiotherapy plan similarity determination device can be a radiotherapy plan similarity determination device. A software system can also be an embedded system that combines software and hardware.

In an optional embodiment, the radiotherapy plan similarity determination device can obtain the third feature corresponding to the first radiotherapy plan, and obtain the fourth feature corresponding to the second radiotherapy plan, where the third feature is the first radiotherapy plan. The overlapping volume histogram information from each radiation source in the plan to the N first organs, and the fourth feature is the overlapping volume histogram information from each radiation source in the second radiotherapy plan to the M second organs. Finally, the radiotherapy plan similarity determining device determines the similarity between the first radiotherapy plan and the second radiotherapy plan based on the first feature, the second feature, the third feature and the fourth feature.

Optionally, the overlapping volume histogram information from each radiation source to the N first organs in the first radiotherapy plan may be statistical distance information from each radiation source relative to the N first organs, wherein the distance statistical information Including the intersection distance information among all the distance information corresponding to the N first organs. In addition, the overlapping volume histogram information from each radiation source to the N first organs in the first radiotherapy plan may also include the spatial correlation between any two first organs, including but not limited to the spatial correlation relationship between the first radiotherapy plan and the N first organs. The spatial correlation between each risk organ of the radiotherapy subject and the radiotherapy target area, and the spatial correlation between different risk organs of the radiotherapy subject corresponding to the first radiotherapy plan.

Correspondingly, the overlapping volume histogram information from each radiation source to the M second organs in the second radiotherapy plan may be the statistical distance information of each radiation source relative to the M second organs, where the distance statistical information Including the cross-part distance information among all the distance information corresponding to the M second organs. In addition, the overlapping volume histogram information from each radiation source to the M second organs in the second radiotherapy plan may also include the spatial correlation between any two second organs, including but not limited to the spatial correlation relationship between the second radiotherapy plan and the M second organs. The spatial correlation between each risk organ of the radiotherapy subject and the radiotherapy target area, and the spatial correlation between different risk organs of the radiotherapy subject corresponding to the second radiotherapy plan.

In an optional embodiment, the radiotherapy plan similarity determination device can generate a first curve corresponding to the first radiotherapy plan based on the first feature and the third feature, and generate the second radiotherapy plan based on the second feature and the fourth feature. The second curve corresponding to the plan, where the first curve is a curve with the first feature as the abscissa and the third feature as the ordinate, and the second curve is a curve with the second feature as the abscissa and the fourth feature as the ordinate. The curve formed. Finally, the radiotherapy plan similarity determining device determines the similarity between the first radiotherapy plan and the second radiotherapy plan based on the first curve and the second curve.

Optionally, Figure 2 is a schematic diagram of an optional curve generated based on distance information and overlapping volume histogram information according to an embodiment of the present application. As shown in Figure 2, the abscissa corresponding to the curve represents the distance from the radiation source to the radiotherapy target. Distance information of areas or organs at risk, for example, r1, r2, d. The ordinate corresponding to the curve represents the overlapping volume histogram information from the radioactive source to the radiotherapy target area or the organ at risk, that is, the distance statistical information of each radioactive source relative to the radiotherapy target area or the organ at risk.

It should be noted that the curve in Figure 2 is only an example, used to schematically illustrate a manifestation of the first curve and/or the second curve. Therefore, the curve in Figure 2 can refer to both the first curve and the first curve. , can also refer to the second curve, and the corresponding horizontal and vertical coordinates can be adaptively changed according to the actual situation.

In an optional embodiment, the radiotherapy plan similarity determination device can display the first curve and the second curve on the same coordinate system, and calculate a graph composed of the first curve and the second curve on the same coordinate system. Then, the radiotherapy plan similarity determination device determines the similarity between the first radiotherapy plan and the second radiotherapy plan based on the area of the graph, where there is a negative correlation between the area of the graph and the similarity.

Optionally, FIG. 3 is a schematic diagram of a graph composed of an optional first curve and a second curve according to an embodiment of the present application. It is easy to understand that if the first curve and the second curve are exactly the same, the two curves will completely overlap in the same coordinate system. If the similarity between the first curve and the second curve is high, then the two curves will The area of the graphic will be smaller. On this basis, this application displays the first curve and the second curve on the same coordinate system and calculates the area of the figure composed of the first curve and the second curve on the same coordinate system, so that the area of the figure can be determined. Similarity between the first radiotherapy plan and the second radiotherapy plan.

In an optional embodiment, in order to obtain the first feature corresponding to the first radiotherapy plan, the radiotherapy plan similarity determination device first obtains the position coordinates of each radiation source in the first radiotherapy plan in the resampled coordinate system. , where the resampled coordinate system is used to expand the horizontal plane size based on the medical image in the first radiotherapy plan. Then, the radiotherapy plan similarity determination device determines the first feature according to the position coordinates and the delineation information corresponding to the first radiotherapy plan, wherein the delineation information is used to characterize each of the N first organs in the first radiotherapy plan. Contour information in medical images.

Optionally, by resampling the coordinate system to expand the horizontal plane size based on the medical images in the first radiotherapy plan, it can be ensured that the position coordinates of each radiation source in the first radiotherapy plan can be accurately obtained to avoid errors due to medical image correspondence. The size of the horizontal plane is too small, resulting in the problem that the position coordinates of some radioactive sources cannot be determined directly.

In an optional embodiment, Figure 4 is an optional flow chart for determining the position coordinates of each radiation source in the first radiotherapy plan in the resampling coordinate system according to the embodiment of the present application, as shown in Figure As shown in 4, it includes the following steps:

Step S401: Obtain the field angle and source axis distance corresponding to each radiation source in the first radiotherapy plan, where the source axis distance corresponding to each radiation source is used to represent the distance from the radiation source to the rotation axis of the gantry.

Alternatively, the field angle can be expressed as θ, and the source axis distance can be expressed as _DSAD .

Step S402: Determine the position coordinates of each radiation source in the first radiation therapy plan in the resampled coordinate system based on the field angle and source axis distance corresponding to each radiation source in the first radiation therapy plan.

Optionally, in step S402, the radiotherapy plan similarity determination device first obtains the position coordinates of each radiation source in the first radiotherapy plan on the first horizontal plane, where the first horizontal plane is the location corresponding to the first radiotherapy plan. The radiotherapy target area of the radiotherapy subject is the horizontal plane of the center point. Subsequently, the radiotherapy plan similarity determination device determines a third radiotherapy plan based on the position coordinates of each radioactive source in the first radiotherapy plan on the first horizontal plane, the field angle corresponding to each radioactive source in the first radiotherapy plan, and the source axis distance. The position coordinates of each radiation source in the radiotherapy plan in the resampled coordinate system.

Alternatively, the position coordinates of the radiation source on the first horizontal plane can be expressed as (X _P , Y _P ), and the position coordinates of the radiation source in the resampled coordinate system can be expressed as (X _S , Y _S ).

Among them, formula (1) shows the calculation formula of X _S.

X _S ＝X _P +D _SAD *sinθ (1)

Formula (2) shows the calculation formula of Y _S.

Y _S ＝Y _P +D _SAD *cosθ (2)

In an optional embodiment, after obtaining the position coordinates of the radioactive source in the resampled coordinate system, it is also necessary to determine the radiotherapy from the radioactive source to the radiotherapy object corresponding to the first radiotherapy plan in combination with the delineation information corresponding to the first radiotherapy plan. The distance information between the target area and at least one organ at risk (i.e., the first feature). For specific operations, please refer to the following formula (3).

M _ROI =DistMap(P _P )*C _ROI (3)

Among them, in formula (3), P _P = (X _P , Y _P ), DistMap is a function used to generate the entire distance distribution map around the radioactive source, and M _ROI represents the first feature corresponding to the radioactive source (the first The feature can be represented as the entire distance distribution map around the radioactive source), and C _ROI represents the delineation information corresponding to the first radiotherapy plan.

Optionally, Figure 5 is an optional distance distribution diagram according to an embodiment of the present application. As shown in Figure 5, the PTV in Figure 5 is the outline image corresponding to the radiotherapy target area (that is, the outline information corresponding to the radiotherapy target area). ), OAR1 in Figure 5 is the outline image corresponding to organ at risk 1, and OAR2 in Figure 5 is the outline image corresponding to organ at risk 2. In addition, the arrows connecting the radioactive source and PTV, OAR1 and OAR2 in Figure 5 indicate the distance information between the radioactive source and PTV, OAR1 and OAR2.

It should be noted that Figure 2 can be generated after Figure 5 is converted. Figure 2 is the statistical form of Figure 5. That is, Figure 2 can also represent the distribution of radioactive sources to organs at risk and radiotherapy target areas on the basis of Figure 5. Overlap volume histogram information.

In an optional embodiment, in order to obtain the second feature corresponding to the second radiotherapy plan, the similarity determination device of the radiotherapy plan can obtain the position coordinates of each radiation source in the second radiotherapy plan in the resampled coordinate system. , and determine the second feature according to the position coordinates and the delineation information corresponding to the second radiotherapy plan, where the delineation information is used to characterize the outline of each of the M second organs in the medical image in the second radiotherapy plan. information.

Among them, obtaining the position coordinates of each radioactive source in the second radiotherapy plan in the resampled coordinate system includes: obtaining the field angle and source axis distance corresponding to each radioactive source in the second radiotherapy plan. According to the second radiotherapy plan The field angle and source axis distance corresponding to each radiation source in the plan determine the position coordinates of each radiation source in the second radiation therapy plan in the resampling coordinate system.

Optionally, determining the position coordinates of each radiation source in the second radiation therapy plan in the resampled coordinate system based on the field angle and source axis distance corresponding to each radiation source in the second radiation therapy plan includes: obtaining the second The position coordinates of each radiation source in the second radiotherapy plan on the second horizontal plane, and based on the position coordinates of each radioactive source on the second horizontal plane in the second radiotherapy plan, the corresponding coordinates of each radioactive source in the second radiotherapy plan The beam angle and source axis distance determine the position coordinates of each radiation source in the second radiotherapy plan in the resampled coordinate system. The second horizontal plane is a horizontal plane with the radiotherapy target area of the radiotherapy subject corresponding to the second radiotherapy plan as the center point.

In an optional embodiment, Figure 6 is a schematic diagram of a process for determining the similarity of radiotherapy plans according to an embodiment of the present application. As shown in Figure 6, first, the first curve and the first curve corresponding to the first radiotherapy plan are generated respectively. The second curve corresponding to the second radiotherapy plan is then used to determine the similarity between the first radiotherapy plan and the second radiotherapy plan through the area of the graph formed by the first curve and the second curve. Among them, Figure 6 also shows the specific process of generating the first curve/second curve. First, the field information of the radiotherapy plan (the first radiotherapy plan or the second radiotherapy plan) is read, where the field information includes the number of fields. and field angle. Then, the position coordinates of the radioactive source are determined on the resampling coordinate system, and the distance distribution map from the radioactive source to the ROI (organs at risk and/or radiotherapy target area) is determined based on the position coordinates. By converting the distance distribution map into a statistical form, the distance distribution map can be Get the first curve/second curve.

It can be seen from the above that, unlike the prior art method of determining the similarity of radiotherapy plans only through image features corresponding to the radiotherapy plans, this application determines the similarity of radiotherapy plans based on distance information from the radioactive source to the radiotherapy target area and organs at risk. degree, as a comparison, image features can usually only represent the outline information of the radiotherapy target area and organs at risk, but cannot represent other information, while the distance information from the radiation source to the radiotherapy target area and organs at risk can represent both the radiation field information and the organ at risk. The relative positional relationship between the radiotherapy source, the radiotherapy target area and the organs at risk. At the same time, because the distance information corresponding to the radiotherapy target area and the organs at risk of different shapes and the radioactive source will be different, therefore, the distance from the radiotherapy source to the radiotherapy target area and The distance information of the organs at risk can actually represent the radiotherapy target area and the shape information of the organs at risk.

It can be seen that compared with the existing technology, the technical solution of the present application can determine the similarity of the radiotherapy plan from more reference dimensions, thereby improving the accuracy of determining the similarity of the radiotherapy plan, thereby solving the problem of comparison in the existing technology. When determining the similarity of radiotherapy plans, comparisons are made only based on image features, which leads to inaccurate technical problems in determining the similarity of radiotherapy plans.

Example 2

According to an embodiment of the present application, an embodiment of a radiotherapy plan similarity determination device is provided. Figure 7 is a schematic diagram of an optional radiotherapy plan similarity determination device according to an embodiment of the present application. As shown in Figure 7, the radiotherapy plan similarity determination device includes: a first acquisition unit 701 and a second acquisition unit 702 and determining unit 703.

Optionally, the first acquisition unit 701 is used to acquire the first characteristics corresponding to the first radiotherapy plan, where the first characteristics are used to characterize each radiation source in the radiation field information formulated in the first radiotherapy plan to N Distance information of each first organ in the first organ, the N first organs include the radiotherapy target area of the radiotherapy subject corresponding to the first radiotherapy plan and at least one organ at risk; the second acquisition unit 702 is used to obtain the second radiotherapy The second feature corresponding to the plan, where the second feature is used to characterize the distance information from each radiation source to each of the M second organs in the radiation field information formulated in the second radiotherapy plan, M The second organ includes the radiotherapy target area of the radiotherapy subject corresponding to the second radiotherapy plan and at least one organ at risk; the determining unit 703 is configured to determine the similarity between the first radiotherapy plan and the second radiotherapy plan based on the first feature and the second feature.

Optionally, the determining unit 703 includes: a first obtaining subunit, a second obtaining subunit, and a first determining subunit. Wherein, the first acquisition subunit is used to acquire the third feature corresponding to the first radiotherapy plan, where the third feature is the overlapping volume histogram information from each radiation source to the N first organs in the first radiotherapy plan; The second acquisition subunit is used to acquire the fourth feature corresponding to the second radiotherapy plan, where the fourth feature is the overlapping volume histogram information from each radiation source to the M second organs in the second radiotherapy plan; first The determining subunit is used to determine the similarity between the first radiotherapy plan and the second radiotherapy plan according to the first feature, the second feature, the third feature and the fourth feature.

Optionally, the first determination subunit includes: a first generation module, a second generation module and a first determination module. Wherein, the first generation module is used to generate a first curve corresponding to the first radiotherapy plan based on the first feature and the third feature, wherein the first curve is composed of the first feature as the abscissa and the third feature as the ordinate. curve; the second generation module is used to generate a second curve corresponding to the second radiotherapy plan based on the second feature and the fourth feature, where the second curve is formed by taking the second feature as the abscissa and the fourth feature as the ordinate. A first determination module is configured to determine the similarity between the first radiotherapy plan and the second radiotherapy plan based on the first curve and the second curve.

Optionally, the first determination module includes: a calculation sub-module and a first determination sub-module. Among them, the calculation sub-module is used to display the first curve and the second curve on the same coordinate system, and calculate the area of the figure composed of the first curve and the second curve on the same coordinate system; the first determination sub-module is used The method is to determine the similarity between the first radiotherapy plan and the second radiotherapy plan based on the area of the graph, where there is a negative correlation between the area of the graph and the similarity.

Optionally, the first obtaining unit 701 includes: a third obtaining subunit and a second determining subunit. Wherein, the third acquisition subunit is used to acquire the position coordinates of each radiation source in the first radiotherapy plan in the resampling coordinate system, where the resampling coordinate system is used as the basis of the medical image in the first radiotherapy plan. to expand the horizontal plane size; the second determination subunit is used to determine the first feature according to the position coordinates and the delineation information corresponding to the first radiotherapy plan, wherein the delineation information is used to characterize the location of each first organ among the N first organs. Contour information in medical images in the first radiotherapy plan.

Optionally, the third acquisition subunit includes: a first acquisition module and a second determination module. Among them, the first acquisition module is used to obtain the field angle and source axis distance corresponding to each radiation source in the first radiotherapy plan, where the source axis distance corresponding to each radiation source is used to characterize the distance between the radiation source and the gantry The distance of the rotation axis; the second determination module is used to determine the distance of each radiation source in the first radiation therapy plan in the resampled coordinate system based on the field angle and source axis distance corresponding to each radiation source in the first radiation therapy plan. Position coordinates.

Optionally, the second determination module includes: a first acquisition sub-module and a second determination sub-module. Among them, the first acquisition sub-module is used to acquire the position coordinates of each radiation source in the first radiotherapy plan on the first horizontal plane, where the first horizontal plane is the radiotherapy target area of the radiotherapy object corresponding to the first radiotherapy plan. The horizontal plane of the center point; the second determination sub-module is used to determine the position coordinates of each radiation source on the first horizontal plane in the first radiation therapy plan, the field angle corresponding to each radiation source in the first radiation therapy plan, and the source The axis distance determines the position coordinates of each radiation source in the first radiotherapy plan in the resampled coordinate system.

Example 3

According to another aspect of the embodiment of the present application, a computer-readable storage medium is also provided. The computer-readable storage medium includes a stored computer program, wherein when the computer program is running, the device where the computer-readable storage medium is located is controlled to perform the above implementation. Method for determining the similarity of any radiotherapy plan in Example 1.

Example 4

According to another aspect of the embodiment of the present application, an electronic device is also provided, including: a processor; and a memory for storing executable instructions of the processor; wherein the processor is configured to perform the above by executing the executable instructions. The method for determining the similarity of any radiotherapy plan in Embodiment 1.

The above serial numbers of the embodiments of the present application are only for description and do not represent the advantages or disadvantages of the embodiments.

In the above-mentioned embodiments of the present application, each embodiment is described with its own emphasis. For parts that are not described in detail in a certain embodiment, please refer to the relevant descriptions of other embodiments.

In the several embodiments provided in this application, it should be understood that the disclosed technical content can be implemented in other ways. The device embodiments described above are only illustrative. For example, the division of units can be a logical functional division. In actual implementation, there may be other division methods. For example, multiple units or components can be combined or integrated into Another system, or some features can be ignored, or not implemented. On the other hand, the coupling or direct coupling or communication connection between each other shown or discussed may be through some interfaces, and the indirect coupling or communication connection of the units or modules may be in electrical or other forms.

Units described as separate components may or may not be physically separate, and components shown as units may or may not be physical units, that is, they may be located in one place, or they may be distributed over multiple units. Some or all of the units can be selected according to actual needs to achieve the purpose of the solution of this embodiment.

In addition, each functional unit in each embodiment of the present application can be integrated into one processing unit, each unit can exist physically alone, or two or more units can be integrated into one unit. The above integrated units can be implemented in the form of hardware or software functional units.

Integrated units may be stored in a computer-readable storage medium if they are implemented in the form of software functional units and sold or used as independent products. Based on this understanding, the technical solution of the present application is essentially or contributes to the existing technology, or all or part of the technical solution can be embodied in the form of a software product, and the computer software product is stored in a storage medium , including several instructions to cause a computer device (which can be a personal computer, a server or a network device, etc.) to execute all or part of the steps of the methods of various embodiments of the present application. The aforementioned storage media include: U disk, read-only memory (ROM, Read-Only Memory), random access memory (RAM, Random Access Memory), mobile hard disk, magnetic disk or optical disk and other media that can store program code. .

The above are only the preferred embodiments of the present application. It should be pointed out that for those of ordinary skill in the art, several improvements and modifications can be made without departing from the principles of the present application. These improvements and modifications should also be regarded as This is the protection scope of this application.

Claims (10)

1. A method for determining the similarity of radiotherapy plans, which is characterized by including: Obtain a first feature corresponding to the first radiotherapy plan, wherein the first feature is used to characterize each radiation source in the radiation field information formulated in the first radiotherapy plan to each of the N first organs. Distance information of an organ, the N first organs include the radiotherapy target area of the radiotherapy subject corresponding to the first radiotherapy plan and at least one organ at risk; Obtain a second feature corresponding to the second radiotherapy plan, wherein the second feature is used to characterize each radiation source to each of the M second organs in the radiation field information formulated in the second radiotherapy plan. Distance information of two organs, the M second organs include the radiotherapy target area of the radiotherapy subject corresponding to the second radiotherapy plan and at least one organ at risk; The similarity between the first radiotherapy plan and the second radiotherapy plan is determined based on the first feature and the second feature. 2. The method for determining the similarity of the radiotherapy plan according to claim 1, wherein the similarity of the first radiotherapy plan and the second radiotherapy plan is determined according to the first feature and the second feature, including : Obtain a third feature corresponding to the first radiotherapy plan, where the third feature is overlapping volume histogram information from each radiation source in the first radiotherapy plan to the N first organs; Obtain a fourth feature corresponding to the second radiotherapy plan, where the fourth feature is overlapping volume histogram information from each radiation source in the second radiotherapy plan to the M second organs; The similarity between the first radiotherapy plan and the second radiotherapy plan is determined according to the first feature, the second feature, the third feature and the fourth feature. 3. The radiotherapy plan similarity determination method according to claim 2, characterized in that the first radiotherapy plan is determined according to the first feature, the second feature, the third feature and the fourth feature. Similarity to the second radiotherapy plan, including: A first curve corresponding to the first radiotherapy plan is generated based on the first feature and the third feature, wherein the first curve is formed by taking the first feature as the abscissa and the third feature as the ordinate. The curve formed by the coordinates; A second curve corresponding to the second radiotherapy plan is generated based on the second feature and the fourth feature, wherein the second curve is formed by taking the second feature as the abscissa and the fourth feature as the ordinate. The curve formed by the coordinates; The similarity between the first radiotherapy plan and the second radiotherapy plan is determined according to the first curve and the second curve. 4. The method for determining the similarity of the radiotherapy plan according to claim 3, wherein the similarity of the first radiotherapy plan and the second radiotherapy plan is determined according to the first curve and the second curve, including : Display the first curve and the second curve on the same coordinate system, and calculate the area of the figure composed of the first curve and the second curve on the same coordinate system; The similarity between the first radiotherapy plan and the second radiotherapy plan is determined according to the area of the graph, where there is a negative correlation between the area of the graph and the similarity. 5. The method for determining similarity of radiotherapy plans according to claim 1, characterized in that obtaining the first feature corresponding to the first radiotherapy plan includes: Obtain the position coordinates of each radiation source in the first radiotherapy plan in a resampled coordinate system, wherein the resampled coordinate system is used to expand the horizontal plane size based on the medical images in the first radiotherapy plan ; The first feature is determined according to the position coordinates and the delineation information corresponding to the first radiotherapy plan, wherein the delineation information is used to characterize each of the N first organs in the first organ. Contour information in medical images in a radiotherapy plan. 6. The radiotherapy plan similarity determination method according to claim 5, characterized in that obtaining the position coordinates of each radiation source in the first radiotherapy plan in the resampled coordinate system includes: Obtain the field angle and source axis distance corresponding to each radiation source in the first radiotherapy plan, where the source axis distance corresponding to each radiation source is used to characterize the distance from the radiation source to the rotation axis of the gantry; The position coordinates of each radiation source in the first radiation therapy plan in the resampled coordinate system are determined based on the field angle and source axis distance corresponding to each radiation source in the first radiation therapy plan. 7. The method for determining the similarity of radiotherapy plans according to claim 6, characterized in that, the radiotherapy plan is determined according to the field angle and source axis distance corresponding to each radioactive source in the first radiotherapy plan. The position coordinates of each radioactive source in the resampled coordinate system include: Obtain the position coordinates of each radiation source in the first radiotherapy plan on a first horizontal plane, where the first horizontal plane is a horizontal plane with the radiotherapy target area of the radiotherapy object corresponding to the first radiotherapy plan as the center point. ; The first radiotherapy plan is determined based on the position coordinates of each radioactive source in the first radiotherapy plan on the first horizontal plane, the field angle corresponding to each radioactive source in the first radiotherapy plan, and the source axis distance. The position coordinates of each radioactive source in the resampled coordinate system. 8. A radiotherapy plan similarity determination device, characterized in that it includes: The first acquisition unit is used to acquire the first characteristics corresponding to the first radiation therapy plan, wherein the first characteristics are used to characterize each radiation source to the Nth radiation source in the radiation field information formulated in the first radiation therapy plan. Distance information of each first organ in an organ, the N first organs including the radiotherapy target area of the radiotherapy subject corresponding to the first radiotherapy plan and at least one organ at risk; The second acquisition unit is used to acquire the second characteristics corresponding to the second radiotherapy plan, wherein the second characteristics are used to characterize each radiation source to the Mth in the radiation field information formulated in the second radiotherapy plan. The distance information of each second organ in the two organs, the M second organs include the radiotherapy target area of the radiotherapy subject corresponding to the second radiotherapy plan and at least one organ at risk; A determining unit configured to determine the similarity between the first radiotherapy plan and the second radiotherapy plan according to the first feature and the second feature. 9. A computer-readable storage medium, characterized in that a computer program is stored in the computer-readable storage medium, wherein when the computer program is running, the device where the computer-readable storage medium is located is controlled to execute claim 1 Method to determine the similarity of radiotherapy plans to any one of 7. 10. An electronic device, characterized in that it includes one or more processors and a memory, the memory being used to store one or more programs, wherein when the one or more programs are processed by the one or more When the processor executes, the one or more processors are caused to implement the similarity determination method of the radiotherapy plan according to any one of claims 1 to 7.