CN116637537A - A two-dimensional microchannel main-side hybrid structure - Google Patents

Abstract

The invention discloses a two-dimensional micro-channel main-side mixing structure, which comprises a main channel and a bypass channel, wherein the main channel and the bypass channel are intersected at a mixing point, and an included angle between the direction of the main channel before entering the mixing point and the outlet direction after mixing the mixing point, namely a first mixing angle is 0 degree; the included angle between the bypass direction before entering the mixing point and the outlet direction after mixing, namely the second mixing angle is not equal to 0 degree and not more than 90 degrees; the mixed micro-channel enters a splitting point after necessary direction adjustment, two paths are formed after the splitting point, and two paths of outlet directions leaving the splitting point form certain included angles with the inlet direction respectively, namely a first splitting angle and a second splitting angle, wherein the first splitting angle and the second splitting angle are equal in size and are not equal to 0 degree and smaller than 90 degrees. The invention overcomes the defects of poor mixability and long reaction time of the heart-shaped structure, and simultaneously solves the defects of large pressure difference between an inlet and an outlet of the Tesla structure, poor fluidity and easy blocking area, thereby being more suitable for continuous flow synthesis.

Description

A two-dimensional microchannel main-side hybrid structure

technical field

The invention relates to the technical field of two-dimensional microchannels, in particular to a main-side mixing structure of a two-dimensional microchannel.

Background technique

As shown in Figure 1, two-dimensional microchannel reaction structures or reactors are commonly used for continuous flow synthesis of chemicals. It usually has two inlets, which inject two kinds of reaction liquids respectively; one outlet, which outputs the mixed liquid of intermediate reactants or finished reaction products. Such microchannels are often processed in the form of a connected two-dimensional groove on a transparent borosilicate or quartz glass plate. If the reactant flows through the microchannel on a glass plate and does not reach the time required to complete the reaction, Multiple plates can be connected in series to form longer reaction channels. In order to better mix the two liquid streams in a limited microchannel and shorten the reaction time, this connected two-dimensional groove is always formed by repeating series of microstructures of a specific shape.

As shown in Figure 2, there must be a mixing point in each microstructure, which is represented by a dot, so that the two liquid flows can be mixed; there must also be a split point, which is represented by a square point, so that the mixed The flow splits into two paths, ready to enter the next microstructure.

Obviously, from the perspective of the role played by microstructures in continuous flow synthesis, although the cross-sectional shape and curved shape of each channel will have an impact, the structural characteristics at the mixing point and splitting point play a key role.

Among the various existing two-dimensional microchannel reaction structures or reactors, there are two most representative structures.

The first is a heart-shaped structure, as shown in Figure 3. The structures at the mixing point and the splitting point of this structure are all symmetrical, and there is no distinction between main and side. As shown in FIG. 4 , at the mixing point, the first mixing angle 3 a and the second mixing angle 3 b are equal in magnitude and both are smaller than 90 degrees. As shown in FIG. 5 , at the splitting point, the first splitting angle 4 a and the second splitting angle 4 b are also equal in size, and neither is greater than 90 degrees. Numerical simulations show that this structure has a small pressure difference between the inlet and outlet, good fluidity, and no clogging area; but the mixing property is poor, and it takes a long time when used in microchannel chemical reactions.

The second is the Tesla structure, as shown in Figure 6. The original intention of Tesla inventing this structure was to design a one-way valve, hoping to prevent the flow in the direction of the main road (shown by the thick solid line). This blocking is achieved by introducing reverse momentum from the flow in the direction of the bypass (shown in bold dashed line) at an obtuse angle to the direction of the main path. When the Tesla structure is used as a microchannel for chemical reactions, each such confluence becomes a mixing point that mixes well because the directions of the two inlet streams have an opposing component. As shown in Figure 7, at the mixing point, the direction of the inlet 1 is in the same direction as the direction of the outlet, or the first mixing angle 3a is 0 degrees; the angle between the direction of the inlet 2 and the direction of the outlet, namely the second mixing angle 3b, is total is greater than 90 degrees. At the same time, the directions of the two branches from each split point are asymmetrical. The direction of one path remains the same, indicated by a dotted line, and the fluidity is better; , may cause blockage in this section when used in microchannel chemical reactions. As shown in Figure 8, at the split point, the inlet direction is in the same direction as the outlet 1 direction, or the first split angle 4a is 0 degrees; the deviation angle from the inlet direction to the outlet 2 direction is the second split angle 4b, Always greater than 0 degrees. Numerical simulations show that although this structure has good mixing properties, it is not suitable for microchannel chemical reactions because of its large pressure difference between inlet and outlet, poor fluidity, and easy-to-block areas. In fact, Tesla's original intention of inventing this structure was not for this occasion.

Contents of the invention

In order to overcome the above defects in the prior art, the object of the present invention is to provide a two-dimensional microchannel main-side mixing structure, which overcomes the shortcomings of poor mixing performance and long reaction time of the heart-shaped structure, and solves the problem of Tesla structure inlet and outlet. It is more suitable for continuous flow synthesis due to the disadvantages of large pressure difference, poor fluidity and easy clogging area.

In order to achieve the above object, the technical scheme adopted in the present invention is:

A two-dimensional micro-channel main-side mixed structure, including two micro-channels, one of which is the main road 5, and the other is a bypass 6, and the main road 5 and the bypass 6 meet at one point to form a mixed road, and the intersection point is a mixed road. Point 1, along the flow direction, at mixing point 1, the angle between the main road 5 and the mixing road is the first mixing angle 3a, the angle between the bypass 6 and the mixing road is the second mixing angle 3b, and the first mixing angle 3a is 0 degrees, that is, the direction of the outlet of the mixing road is consistent with the direction of the main road 5; the second mixing angle 3b is not equal to 0 degrees and not greater than 90 degrees;

The micro-channel formed by the mixed mixed road enters the split point 2 after the necessary direction adjustment, and forms two roads after the split point 2, and the exit directions of the two roads after leaving the split point 2 form a certain The included angle, the included angle is the first split angle 4a and the second split angle 4b, the first split angle 4a and the second split angle 4b are equal in size, not equal to 0 degrees and less than 90 degrees.

The split two-way microchannel enters the next mixing point after necessary direction adjustment, and the mixing method is similar to the previous mixing point 1, and the main road 5 and the bypass 6 of the latter mixing are separated from the split before the split. Looking in the direction of the main road 5, the left and right are reversed from the previous mixing.

According to needs, the above-mentioned mixing, splitting and re-mixing methods can be repeated many times.

Flowability is improved by reducing the second mixing angle 3b and/or two equal first splitting angles 4a and second splitting angles 4b as required.

The starting point mixing point of the two-way microchannel is divided into three inlets or two inlets;

When the starting point is three inlets, the middle inlet is injected with the first reaction solution, and the inlets on both sides are equally injected with the second reaction solution;

When the starting points are two inlets, the two inlets are respectively injected with a reaction solution.

Beneficial effects of the present invention:

At the blending point, the present invention abandons the symmetry of the cardioid structure and accommodates the asymmetry of the Tesla structure. Compared to the Tesla configuration, the first mixing angle is also kept at zero, but the second mixing angle is changed from obtuse to right or acute. The first mixing angle is kept at zero, which better retains the mixing effect of the Tesla structure; the second mixing angle is changed from an obtuse angle to a right angle or an acute angle, which eliminates the recoil force introduced by the Tesla structure for blocking flow, and more Suitable for continuous flow synthesis.

At the split point, the present invention abandons the asymmetry of the Tesla structure and draws on the symmetry of the heart-shaped structure, because one of the two roads split by the Tesla structure has poor mobility, before entering the next mixing point A period of time, it is easy to cause blockage of reactants, but the latter does not have this problem.

Therefore, the microchannel structure of the present invention has good mixing uniformity, no easy-to-block area, and is more suitable for continuous flow synthesis.

Description of drawings:

Figure 1 is a general layout diagram of microchannels used for continuous flow synthesis in the prior art.

Figure 2 is a schematic diagram of microchannel flow for continuous flow synthesis in the prior art.

Fig. 3 is a schematic diagram of a heart-shaped structure in the prior art.

Fig. 4 is a schematic diagram of a mixing point of a heart-shaped structure in the prior art.

Fig. 5 is a schematic diagram of splitting points of a heart-shaped structure in the prior art.

Fig. 6 is a schematic structural diagram of a Tesla in the prior art.

Fig. 7 is a schematic diagram of a mixing point of a Tesla structure in the prior art.

Fig. 8 is a schematic diagram of a split point of a Tesla structure in the prior art.

Fig. 9 is a schematic structural diagram of the present invention.

Figure 10 is a schematic diagram of a mixing point of the present invention.

Fig. 11 is a schematic diagram of splitting points of the present invention.

Fig. 12 is a schematic diagram of a deformed structure of the present invention.

Fig. 13 is a schematic diagram of a specific embodiment of the present invention.

Fig. 14 is a schematic diagram of the second embodiment of the present invention.

Fig. 15 is a schematic diagram of a third embodiment of the present invention.

Fig. 16 is a schematic diagram showing comparison of mixing effects of various structures after passing through three mixing points.

Among them: 1 blending point, 2 splitting points, 3a first blending corner, 3b second blending corner, 4a first splitting corner, 4b second splitting corner, 5 main road, 6 bypass.

Detailed ways

The present invention is described in further detail below in conjunction with embodiment.

As shown in Figure 9: a two-dimensional micro-channel main-side mixed structure, including two micro-channels, one of which is the main road 5, and the other is a bypass 6, and the main road 5 and the bypass 6 meet at one point to form a mixed road. Road, the intersection point is the mixing point 1, along the flow direction, at the mixing point 1, the angle between the main road 5 and the mixing road is the first mixing angle 3a, and the angle between the bypass 6 and the mixing road is the second mixing angle 3b, The first mixing angle 3a is 0 degrees, that is, the direction of the outlet of the mixing road is consistent with the direction of the main road 5; the second mixing angle 3b is not equal to 0 degrees and not greater than 90 degrees; (as shown in Figure 10)

The micro-channel formed by the mixed mixed road enters the split point 2 after the necessary direction adjustment, and forms two roads after the split point 2, and the exit directions of the two roads after leaving the split point 2 form a certain The included angle, the included angle is the first split angle 4a and the second split angle 4b, the first split angle 4a and the second split angle 4b are equal in size, not equal to 0 degrees and less than 90 degrees. (as shown in Figure 11)

The split two-way microchannel enters the next mixing point after necessary direction adjustment, and the mixing method is similar to the previous mixing point 1, and the main road 5 and the bypass 6 of the latter mixing are separated from the split before the split. Looking in the direction of the main road 5, the left and right are reversed from the previous mixing.

As shown in Figure 12: as required, the above mixing, splitting and remixing can be repeated many times.

Flowability is improved by reducing the second mixing angle 3b and/or two equal first splitting angles 4a and second splitting angles 4b as required.

Example 1:

As shown in Figure 13, the scheme has three inlets, subject to the direction shown in the attached figure, on the left side of the figure, the first mixing point is a three-in and two-out mixing point, when used, the middle inlet is injected into the first type The reaction solution is used, and the inlets on both sides are equally injected into the second reaction solution. The structure of the mixing point of this scheme is complex, but the mixing effect is very good. As the first mixing point of the microchannel, it can speed up the synthesis process.

Example 2:

As shown in Figure 14, the scheme has two entrances, which are on the left side of the figure, subject to the direction shown in the accompanying drawing. A reaction solution is injected from the two inlets respectively. The first mixing point of this scheme is like the other mixing points, with only normal mixing effects at the inlet.

Example 3:

As shown in Figure 15, two road microchannels, one of them is the first main road 51, and the other road is the first bypass 61, and the first main road 51 and the first bypass 61 meet at one point to form the first mixing point 11, Along the flow direction, at the first mixing point 11, the microchannel formed by the mixed mixing road enters the first split point 21 after necessary direction adjustment, and forms two roads after the first split point 21, and is divided into the second main road 52 and the second bypass 62, the second main road 52, the second bypass 62 and the first main road 51, the first bypass 61 from the direction of the first main road 51 before splitting, and the main road when it was mixed with the previous time , The left and right directions of the bypass are reversed.

The split two-way microchannels enter the next mixing point after necessary direction adjustment, and the mixing method is similar to the previous mixing point 1.

Figure 16 from left to right shows the heart-shaped structure of the prior art, the Tesla structure of the prior art, the structure of the present invention and the deformed structure of the present invention respectively, under the same input conditions, after passing through three mixing points respectively, the mixing effect Numerical simulation, the comparison of simulation results is shown in the table below. The results show that in the third and fourth drawings of the present invention, although the overall fluidity is slightly poor and the mixing separation is medium, they have the best mixing uniformity, and there is no easy-to-block area, which is better than that of the heart-shaped structure and The Tesla structure is more suitable for continuous flow synthesis.

It can be seen from the circuit in the second drawing in Figure 16 that the Tesla structure of the prior art has the smallest mixing separation degree, the largest inlet and outlet pressure difference, and the overall channel has a channel that is easy to block;

It can be seen from the circuit in the first drawing in accompanying drawing 16 that the heart-shaped structure in the prior art has the worst mixing uniformity and the largest mixing separation.

Claims (5)

1. The two-dimensional micro-channel main and side mixing structure is characterized by comprising two micro-channels, wherein one micro-channel is a main channel (5), the other micro-channel is a bypass (6), the main channel (5) and the bypass (6) are intersected at one point to form a mixed channel, the intersection point is a mixing point (1), along the flowing direction, an included angle between the main channel (5) and the mixed channel is a first mixing angle (3 a), an included angle between the bypass (6) and the mixed channel is a second mixing angle (3 b), the first mixing angle (3 a) is 0 DEG, namely the outlet direction of the mixed channel is consistent with the direction of the main channel (5); the second mixing angle (3 b) is not equal to 0 degrees and not greater than 90 degrees;

the micro-channel formed by the mixed paths enters the splitting point (2) after necessary direction adjustment, two paths are formed after the splitting point (2), two paths of outlet directions leaving the splitting point (2) form certain included angles with the micro-channel direction formed by the mixed paths respectively, the included angles are a first splitting angle (4 a) and a second splitting angle (4 b), and the first splitting angle (4 a) and the second splitting angle (4 b) are equal in angle size, are not equal to 0 degrees and are smaller than 90 degrees.

2. The two-dimensional microchannel main and bypass mixing structure according to claim 1, wherein the two channels after splitting enter the next mixing point after necessary direction adjustment, the mixing mode is similar to the previous mixing mode, and the division of the main channel (5) and the bypass (6) of the next mixing mode is left and right exchanged with the previous mixing mode when seen from the direction of the main channel (5) before splitting.

3. The two-dimensional microchannel main and side mixing structure according to claim 1, wherein the mixing and splitting and remixing are repeated a plurality of times.

4. A two-dimensional microchannel primary and secondary mixing structure according to claim 1, characterized in that the flowability is improved by reducing the second mixing angle (3 b) and/or two equal first and second splitting angles (4 a, 4 b).

5. The two-dimensional microchannel main and side mixing structure according to claim 1, wherein the starting point mixing point of the two channels is divided into three inlets or two inlets;

when the starting point is three inlets, the first reaction liquid is injected into the middle inlet, and the second reaction liquid is injected into the inlets on the two sides in equal quantity;

when the starting point is two inlets, two inlets are respectively filled with a reaction liquid.