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CN116380903A - Sample processing equipment - Google Patents

Sample processing equipment Download PDF

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Publication number
CN116380903A
CN116380903A CN202211622018.6A CN202211622018A CN116380903A CN 116380903 A CN116380903 A CN 116380903A CN 202211622018 A CN202211622018 A CN 202211622018A CN 116380903 A CN116380903 A CN 116380903A
Authority
CN
China
Prior art keywords
slide
detection
printing
unit
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202211622018.6A
Other languages
Chinese (zh)
Inventor
刘忠刚
闫红力
邓健波
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen Reetoo Biotechnology Co Ltd
Original Assignee
Shenzhen Reetoo Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen Reetoo Biotechnology Co Ltd filed Critical Shenzhen Reetoo Biotechnology Co Ltd
Priority to CN202211622018.6A priority Critical patent/CN116380903A/en
Publication of CN116380903A publication Critical patent/CN116380903A/en
Pending legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B41PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41JTYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J3/00Typewriters or selective printing or marking mechanisms characterised by the purpose for which they are constructed
    • B41J3/407Typewriters or selective printing or marking mechanisms characterised by the purpose for which they are constructed for marking on special material
    • B41J3/4073Printing on three-dimensional objects not being in sheet or web form, e.g. spherical or cubic objects
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B07SEPARATING SOLIDS FROM SOLIDS; SORTING
    • B07CPOSTAL SORTING; SORTING INDIVIDUAL ARTICLES, OR BULK MATERIAL FIT TO BE SORTED PIECE-MEAL, e.g. BY PICKING
    • B07C5/00Sorting according to a characteristic or feature of the articles or material being sorted, e.g. by control effected by devices which detect or measure such characteristic or feature; Sorting by manually actuated devices, e.g. switches
    • B07C5/34Sorting according to other particular properties
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B07SEPARATING SOLIDS FROM SOLIDS; SORTING
    • B07CPOSTAL SORTING; SORTING INDIVIDUAL ARTICLES, OR BULK MATERIAL FIT TO BE SORTED PIECE-MEAL, e.g. BY PICKING
    • B07C5/00Sorting according to a characteristic or feature of the articles or material being sorted, e.g. by control effected by devices which detect or measure such characteristic or feature; Sorting by manually actuated devices, e.g. switches
    • B07C5/36Sorting apparatus characterised by the means used for distribution
    • B07C5/361Processing or control devices therefor, e.g. escort memory
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B41PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41JTYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J3/00Typewriters or selective printing or marking mechanisms characterised by the purpose for which they are constructed
    • B41J3/44Typewriters or selective printing mechanisms having dual functions or combined with, or coupled to, apparatus performing other functions
    • B41J3/445Printers integrated in other types of apparatus, e.g. printers integrated in cameras
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/88Investigating the presence of flaws or contamination
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/88Investigating the presence of flaws or contamination
    • G01N21/91Investigating the presence of flaws or contamination using penetration of dyes, e.g. fluorescent ink

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Manufacturing & Machinery (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Accessory Devices And Overall Control Thereof (AREA)
  • User Interface Of Digital Computer (AREA)

Abstract

The application provides a sample processing device, the sample processing device includes: the slide printing unit is used for performing slide printing on the slide according to the user identity information of the sample so as to form a user identity mark on the slide; a processing unit for processing a sample on a slide; the first detection unit is used for detecting whether the slide meets detection conditions or not, so that the slide printing unit prints the slide meeting the first detection conditions and/or the slide meeting the second detection conditions to form a first detection mark on the slide meeting the first detection conditions and/or the slide meeting the second detection conditions, and therefore the slide meeting the first detection conditions and/or the slide meeting the second detection conditions are distinguished through the first detection mark.

Description

Sample processing equipment
Technical Field
The application relates to the technical field of medical instruments, in particular to sample processing equipment.
Background
In disease diagnosis and treatment, a smear is formed by coating a sample on a slide through a smear pushing operation, then a smear is dyed to finish a smear, and finally a detection result is obtained by detecting the smear, so that a reference basis is provided for a doctor to diagnose the disease.
In the prior art, before detection, a qualified slide and an unqualified slide are generally placed in a slide basket, and then whether the slide in the slide basket is qualified or not is distinguished in a manual mode, so that errors are easy to occur in the mode, and the labor cost is high.
Disclosure of Invention
The application mainly provides sample processing equipment, can avoid distinguishing the slide that satisfies qualified standard and the slide that does not satisfy qualified standard and go wrong problem when making mistakes, distinguish the mode simple, reduce human cost.
In order to solve the technical problems, one technical scheme adopted by the application is as follows: there is provided a sample processing apparatus comprising: the slide printing unit is used for performing slide printing on the slide according to the user identity information of the sample so as to form a user identity mark on the slide; a processing unit for processing a sample on the slide; and the first detection unit is used for detecting whether the slide meets detection conditions or not, so that the slide printing unit prints the slide meeting the first detection conditions and/or the slide meeting the second detection conditions to form a first detection mark on the slide meeting the first detection conditions and/or the slide meeting the second detection conditions.
In a specific embodiment, the processing unit is configured to apply a sample to the slide, the sample processing apparatus further includes a conveying unit, the conveying unit includes a conveying carrier mechanism and a conveying driving mechanism, the conveying carrier mechanism is configured to carry the slide, the conveying driving mechanism is connected to the conveying carrier mechanism to drive the conveying carrier mechanism to move, a slide printing position and a first detection position are respectively provided along a movement track of the conveying carrier mechanism, the slide printing unit is configured to print the slide on the slide at the slide printing position, and the first detection unit is configured to detect whether the slide meets a detection condition at the first detection position; the processing unit is used for coating a sample on the slide at the first detection position; or a slide pushing position is further arranged along the motion track of the conveying bearing mechanism, and the processing unit is used for coating the sample on the slide at the slide pushing position.
In a specific embodiment, the conveying driving mechanism is used for driving the conveying bearing mechanism to sequentially move the slide to the slide printing position and the first detection position, so that the slide printing unit prints the slide for the first time at the slide printing position according to user identity information of a sample, and after the detection of the first detection unit is completed, the conveying driving mechanism drives the conveying bearing mechanism to return the slide to the slide printing position, so that the slide printing unit prints the slide meeting the first detection condition and/or the slide meeting the second detection condition for the second time at the slide printing position.
In a specific embodiment, the slide printing position includes a first printing position and a second printing position, the slide printing unit includes a first printing module and a second printing module, the conveying driving mechanism is configured to drive the conveying and bearing mechanism to sequentially move the slide to the first printing position and the first detecting position, so that the first printing module prints the slide on the first printing position according to the user identity information of the sample, and after the detection of the first detecting unit is completed, the conveying driving mechanism drives the conveying and bearing mechanism to move the slide to the second printing position, so that the second printing module prints the slide meeting the first detecting condition and/or the slide meeting the second detecting condition for the second time.
In a specific embodiment, the slide printing unit is used for performing first slide printing on the slide according to user identity information of a sample, the processing unit is used for coating the sample on the slide after the first slide printing to form a smear, the first detection unit is used for detecting whether the smear meets detection conditions, and the slide printing unit is used for performing second slide printing on the smear meeting first detection conditions of the qualification standard and/or the smear meeting second detection conditions.
In a specific embodiment, the slide printing unit is configured to perform first slide printing on the slide according to user identity information of a sample, the first detection unit is configured to detect whether the slide after the first slide printing meets a detection condition, the slide printing unit is configured to perform second slide printing on the slide meeting the first detection condition and/or the slide meeting the second detection condition, and the processing unit is configured to apply the sample on the slide after the second slide printing.
In a specific embodiment, the first detection unit is configured to detect whether the sample meets at least one of a pushing condition, whether the processing unit works normally, and whether the sample coated on the slide meets a coating standard.
In a specific embodiment, the sample processing device further comprises a staining unit for staining the slide.
In a specific embodiment, the sample processing device further includes a second detection unit, where the second detection unit is configured to detect whether the stained slide meets a staining condition; the slide printing unit is also used for performing slide printing on the slide meeting the dyeing condition and/or not meeting the dyeing condition so as to form a second detection mark on the slide meeting the dyeing condition and/or not meeting the dyeing condition; or the sample processing apparatus further comprises a staining printing unit for performing slide printing on a slide that satisfies and/or does not satisfy the staining condition to form a second detection mark on the slide that satisfies and/or does not satisfy the staining condition.
In a specific embodiment, the second detection unit is configured to detect at least one of whether the staining quality of the stained slide is acceptable, whether the number of samples on the slide is acceptable, and whether the transmittance of the slide is acceptable.
The beneficial effects of this application are: unlike the prior art, the sample processing apparatus provided in the embodiment of the present application includes: the slide printing unit is used for performing slide printing on the slide according to the user identity information of the sample so as to form a user identity mark on the slide; a processing unit for processing a sample on the slide; the first detection unit is used for detecting whether the slide meets detection conditions or not, so that the slide printing unit prints the slide meeting the first detection conditions and/or the slide meeting the second detection conditions to form a first detection mark on the slide meeting the first detection conditions and/or the slide meeting the second detection conditions, and therefore the slide meeting the first detection conditions and/or the slide meeting the second detection conditions can be distinguished through the first detection mark.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are needed in the description of the embodiments will be briefly introduced below, it being obvious that the drawings in the following description are only some embodiments of the present application, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic view of a perspective assembly of an embodiment of a sample processing device provided herein;
FIG. 2 is a schematic exploded perspective view of the sample processing device of FIG. 1;
FIG. 3 is a schematic view of a perspective assembly of the processing unit of FIG. 2;
FIG. 4 is a schematic block diagram of the first detection unit of FIG. 2;
fig. 5 is a schematic perspective view of the conveying unit of fig. 2;
FIG. 6 is a schematic block diagram illustrating the location of one embodiment of the sample processing device of FIG. 1;
FIG. 7 is a schematic block diagram of another embodiment of the first detection bit of FIG. 6;
FIG. 8 is a schematic block diagram of another embodiment of the first detection bit of FIG. 7;
FIG. 9 is a schematic block diagram of another embodiment of the slide print station of FIG. 6;
fig. 10 is a schematic perspective view of the transfer unit of fig. 2;
fig. 11 is a schematic perspective view of the dyeing unit and the gripping unit in fig. 2.
Detailed Description
The present application is described in further detail below with reference to the drawings and the embodiments. It is specifically noted that the following embodiments are merely for illustrating the present application, but do not limit the scope of the present application. Likewise, the following embodiments are only some, but not all, of the embodiments of the present application, and all other embodiments obtained by one of ordinary skill in the art without inventive effort are within the scope of the present application.
The terms "first," "second," "third," and the like in this application are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first", "a second", and "a third" may explicitly or implicitly include at least one such feature. In the description of the present application, the meaning of "plurality" means at least two, such as two, three, etc., unless explicitly specified otherwise. All directional indications (such as up, down, left, right, front, back … …) in this embodiment are merely used to explain the relative positional relationship, movement, etc. between the components in a particular gesture (as shown in the drawings), and if the particular gesture changes, the directional indication changes accordingly. Furthermore, the terms "comprise" and "have," as well as any variations thereof, are intended to cover a non-exclusive inclusion. A process, method, system, article, or apparatus that comprises a list of steps or elements is not limited to only those listed but may optionally include other steps or elements not listed or inherent to such process, method, article, or apparatus.
Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment may be included in at least one embodiment of the present application. The appearances of such phrases in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. Those skilled in the art will explicitly and implicitly understand that the embodiments described herein may be combined with other embodiments.
Referring to fig. 1 and 2 together, fig. 1 is a schematic perspective assembly structure of an embodiment of a sample processing apparatus 10, and fig. 2 is a schematic perspective exploded structure of the sample processing apparatus 10 in fig. 1, where the sample processing apparatus 10 in this embodiment includes a slide printing unit 11, a processing unit 12, and a first detecting unit 13.
The slide printing unit 11 is configured to perform slide printing on the slide 110 according to user identity information of a sample, so as to form a user identity mark on the slide 110.
For example, in practical application, the smear formed by applying the sample on the slide 110 by the slide pushing operation of the sample processing apparatus 10 in this embodiment is for detecting the sample on the smear later, such as by microscopic detection, so as to provide a reference basis for diagnosing diseases for a doctor, and in order to avoid the situation that the user does not match with the diagnosis result, it is necessary to ensure that the sample on the smear matches with the identity of the user, so that the slide printing unit 11 in this embodiment is used for forming a user identity mark on the slide 110, where the user identity mark marks the identity information of the user corresponding to the sample.
Optionally, in practical application, the slide printing unit 11 may select a carbon tape printing mode to perform slide printing on the slide 110, or may select other printing modes, such as laser printing, which is not limited.
Referring to fig. 3, fig. 3 is a schematic perspective assembly structure of the processing unit 12 in fig. 2, where the processing unit 12 is used to process a sample on the slide 110, and in this embodiment, the processing unit 12 is used to apply the sample on the slide 110, so that a smear is formed by a pushing operation of the processing unit 12, and in other embodiments, the processing unit 12 may process the sample on the slide 110 by other methods, such as settling the sample on the slide 110.
The processing unit 12 includes a pusher driving mechanism 121 and a pusher mounting mechanism 122, the pusher mounting mechanism 122 is used for mounting the pusher 120, and the pusher driving mechanism 121 is connected with the pusher mounting mechanism 122 to drive the pusher 120 to move, so as to apply the sample on the slide 110.
In this embodiment, the push-piece driving mechanism 121 includes a first push-piece driving component 1211 and a second push-piece driving component 1212, where the first push-piece driving component 1211 is connected to the push-piece mounting mechanism 122, and the second push-piece driving component 1212 is connected to the first push-piece driving component 1211, so that the first push-piece driving component 1211 drives the push-piece 120 to move in a first push-piece direction a, and the second push-piece driving component 1212 drives the push-piece 120 to move in a second push-piece direction B, so as to complete the push-piece operation.
Alternatively, in this embodiment, the first pusher driving assembly 1211 and the second pusher driving assembly 1212 are both driven by a screw motor, and in other embodiments, other driving methods, such as a cylinder, may be used, which is not limited thereto.
Referring to fig. 4, fig. 4 is a schematic block diagram of the first detection unit 13 in fig. 2, where the first detection unit 13 is configured to detect whether the slide 110 meets a detection condition, so that the slide printing unit 11 prints the slide 110 meeting the first detection condition and/or the slide 110 meeting the second detection condition to form a first detection mark on the slide 110 meeting the first detection condition and/or the slide 110 meeting the second detection condition, so that the slide 110 meeting the first detection condition and/or the slide 110 meeting the second detection condition are distinguished by the first detection mark.
Wherein, the first detecting unit 13 is configured to detect whether the sample meets at least one of a pushing condition, whether the processing unit 12 works normally, and whether the sample coated on the slide 110 meets a coating standard, for example, when the first detecting unit 13 is configured to detect whether the sample meets the pushing condition, whether the viscosity of the sample is too high or too low; for example, when the first detecting unit 13 is configured to detect whether the processing unit 12 is operating normally, it can detect whether the processing unit 12 is interrupted during the pushing process, so that the pushing failure is caused; for example, when the first detecting unit 13 is used to detect whether the sample coated on the slide 110 meets the coating standard, it may be detected whether the sample is immersed in the print area, whether the sample is uniformly coated, whether the coating thickness is appropriate, or the like after the processing unit 12 applies the sample to the slide 110.
For convenience of explanation, taking herein as an example that the first detection unit 13 is used to detect whether the sample coating on the slide 110 is uniform, the above-mentioned first detection condition may be a qualified slide, the second detection condition may be a non-qualified slide and/or whether the slide cannot be judged to be qualified, the judgment criterion of the qualified slide may be any one or more of the above description, if the slide printing unit 11 performs slide printing on only the slide 110 satisfying the first detection condition or the slide 110 satisfying the second detection condition, the slide printing unit 11 performs slide printing on the slide 110 satisfying the first detection condition or the slide 110 satisfying the second detection condition according to the detection result after the detection by the first detection unit 13 is completed, so as to form the first detection mark on the slide 110 satisfying the first detection condition or the slide 110 satisfying the second detection condition; if the slide printing unit 11 prints the slide 110 satisfying the first detection condition and the slide 110 satisfying the second detection condition on the slide 110 satisfying the first detection condition, respectively, different first detection marks may be formed on the slide 110 satisfying the first detection condition and the slide 110 satisfying the second detection condition, for example, a pass mark may be formed on a pass slide 110, a fail mark may be formed on a fail slide, and a problematic mark may be formed on a fail slide, it being understood that the specific form of the first detection marks may be set according to actual needs, which is not limited.
The first detecting unit 13 includes an acquiring module 131 and an identifying module 132, where the acquiring module 131 is configured to acquire slide information of the slide 110, for example, the acquiring module 131 acquires a slide image of the slide 110 in a photographing manner, and the identifying module 132 is in signal connection with the acquiring module 131 to identify the slide information, so as to determine whether the slide 110 meets a detection condition.
Referring to fig. 5 and 6 together, fig. 5 is a schematic perspective view of the conveying unit 14 in fig. 2, fig. 6 is a schematic block diagram illustrating a position of an embodiment of the sample processing apparatus 10 in fig. 1, the sample processing apparatus 10 in this embodiment further includes the conveying unit 14, the conveying unit 14 includes a conveying carrier 141 and a conveying driving mechanism 142, the conveying carrier 141 is used for carrying the slide 110, and the conveying driving mechanism 142 is connected to the conveying carrier 141 to drive the conveying carrier 141 to move.
The slide printing unit 11 is configured to print a slide on the slide 110 at the slide printing position P1, and the first detecting unit 13 is configured to detect whether the slide 110 meets a detection condition at the first detecting position P2 along the movement track of the conveying and carrying mechanism 142.
In one embodiment, the processing unit 12 is configured to apply the sample on the slide at the first detection position P2, that is, the pushing operation of the processing unit 12 and the detection operation of the first detection unit 13 are at the same position.
Referring to fig. 7 and 8 together, fig. 7 is a schematic block diagram of another embodiment of the first detection position P2 in fig. 6, fig. 8 is a schematic block diagram of another embodiment of the first detection position P2 in fig. 7, in yet another embodiment, a pushing position P3 is further provided along the motion track of the conveying and carrying mechanism 141, and the processing unit 12 is configured to apply the sample on the slide 110 at the pushing position P3, that is, the pushing operation of the processing unit 12 and the detection operation of the first detection unit 13 are not in the same position.
In this further embodiment, as shown in fig. 7, the slide printing position P1, the slide pushing position P3, and the first detection position P2 are sequentially arranged along the movement track of the conveyance carrier 141, or as shown in fig. 8, the slide printing position P1, the first detection position P2, and the slide pushing position P3 are sequentially arranged along the movement track of the conveyance carrier 141.
In a specific application scenario, the conveying driving mechanism 142 is configured to drive the conveying and bearing mechanism 141 to sequentially move the slide 110 to the slide printing position P1 and the first detection position P2, so that the slide printing unit 11 performs first slide printing on the slide 110 at the slide printing position P1 according to the user identity information of the sample, and after the detection by the first detection unit 13 is completed, the conveying and bearing mechanism 142 is driven by the conveying and bearing mechanism 141 to return the slide 110 to the slide printing position P1, so that the slide printing unit 11 performs second slide printing on the slide 110 meeting the first detection condition and/or the slide 110 meeting the second detection condition at the slide printing position P1.
Referring to fig. 9, fig. 9 is a schematic block diagram of another embodiment of the slide printing position P1 in fig. 6, in another specific application scenario, the slide printing position P1 includes a first printing position P11 and a second printing position P12, the slide printing unit 11 includes a first printing module 111 and a second printing module 112, the conveying driving mechanism 142 is configured to drive the conveying carrier mechanism 141 to sequentially move the slide 110 to the first printing position P11 and the first detecting position P2, so that the first printing module 111 prints a first slide on the slide 110 at the first printing position P11 according to the user identity information of the sample, and after the detection of the first detecting unit 13 is completed, the conveying driving mechanism 142 drives the conveying carrier mechanism 141 to move the slide 110 to the second printing position P12, so that the second printing module 112 prints a second slide on the slide 110 meeting the first detecting condition and/or the slide 110 meeting the second detecting condition.
Optionally, the slide printing unit 11 is configured to perform a first slide printing on the slide 110 according to the user identity information of the sample, the processing unit 12 is configured to apply the sample on the slide 110 after the first slide printing to form a smear, the first detecting unit 13 is configured to detect whether the smear satisfies the detection condition, and the slide printing unit 11 is configured to perform a second slide printing on the smear full of the first detection condition and/or the smear satisfying the second detection condition, that is, in this case, the first slide printing of the slide printing unit 11, the pushing operation of the processing unit 12, the detecting operation of the first detecting unit 13, and the second slide printing of the slide printing unit 11 are sequentially performed.
Optionally, the slide printing unit 11 is configured to perform first slide printing on the slide according to the user identity information of the sample, the first detecting unit 13 is configured to detect whether the slide 110 after the first slide printing satisfies the detection condition, the slide printing unit 13 is configured to perform second slide printing on the slide 110 satisfying the first detection condition and/or the slide 110 satisfying the second detection condition, and the processing unit 12 is configured to apply the sample on the slide 110 after the second slide printing, that is, in this case, the first slide printing of the slide printing unit 11, the detection of the first detecting unit 13, and the slide pushing operation of the second slide printing and processing unit 12 of the slide printing unit 11 are sequentially performed.
With further reference to fig. 6-9, the sample processing device 10 in this embodiment further includes a slide storage unit 15 for storing a slide 110.
A first slide receiving position P4 is further provided along the movement track of the conveying and carrying mechanism 141, that is, the conveying and carrying mechanism 141 receives the slide 110 stored in the slide storage unit at the first slide receiving position P4.
The first slide receiving position P4, the slide printing position P1, and the first detecting position P2 are sequentially set along the movement track of the conveying and carrying mechanism 141.
As shown in fig. 7, the first slide receiving position P4, the slide printing position P1, the slide pushing position P3, and the first detection position P2 are sequentially arranged along the movement locus of the conveyance carrier 141.
As shown in fig. 8, the first slide receiving position P4, the slide printing position P1, the slide pushing position P2, and the first detection position P2 are sequentially arranged along the movement locus of the conveyance carrier 141.
Further, the sample processing device 10 in the present embodiment further includes a loading unit 16, and the loading unit 16 is configured to load a sample onto the slide 110.
Referring to fig. 10, fig. 10 is a schematic perspective view of the transfer unit 17 in fig. 2, and the sample processing apparatus 10 in this embodiment further includes the transfer unit 17, where the transfer unit 17 is configured to receive the slide 110 satisfying the first detection condition and/or the slide 110 satisfying the second detection condition on the conveying carrier 141, so that the slide 110 satisfying the first detection condition and/or the slide 110 satisfying the second detection condition is transferred to the slide loading object.
For example, the slide loading object is a slide basket, and the transferring unit 17 is configured to receive the slide 110 satisfying the first detection condition and/or the slide 110 satisfying the second detection condition on the conveying and carrying mechanism 141, so that the slide 110 satisfying the first detection condition and/or the slide 110 satisfying the second detection condition are transferred to the same slide basket, and then only the first detection mark is needed to distinguish which slide 110 in the slide basket is the slide 110 satisfying the first detection condition and which slide 110 is the slide 110 satisfying the second detection condition, which is simple and convenient.
The transferring unit 17 includes a pushing component 171 and a transferring component 172, where the pushing component 171 includes a pushing driving mechanism 1711 and a pushing member 1712, and the pushing driving mechanism 1711 is connected to the pushing member 1712 to drive the pushing member 1712 to push the slide 110 meeting the first detection condition and/or the slide 110 meeting the second detection condition from the conveying carrier 141 to the transferring component 172, so that the slide 110 meeting the first detection condition and/or the slide 110 meeting the second detection condition are transferred from the transferring component 172 to the slide loading object.
The transfer assembly 172 includes a first transfer driving mechanism 1721 and a receiving member 1722, wherein the first transfer driving mechanism 1721 is connected to the receiving member 1722 to drive the receiving member 1722 to move, and a second slide receiving position P6 and a clamping position P7 are provided along a movement track of the receiving member 1722, so that the receiving member 1722 receives the slide 110 satisfying the first detection condition and/or the slide 110 satisfying the second detection condition on the conveying and carrying mechanism 141 at the second slide receiving position P6, and then the slide 110 satisfying the first detection condition and/or the slide 110 satisfying the second detection condition is transferred to the slide loading object at the clamping position P7.
Further, the transfer assembly 172 in this embodiment further includes a second transfer driving mechanism 1723, where the second transfer driving mechanism 1723 is connected to the first transfer driving mechanism 1721 and the receiving member 1722, respectively, so that the second transfer driving mechanism 1723 drives the slide 110 satisfying the first detection condition and/or the slide 110 satisfying the second detection condition to move from the receiving state to the gripping state, for example, when the receiving member 1722 receives the slide 110 satisfying the first detection condition and/or the slide 110 satisfying the second detection condition, the slide 110 satisfying the first detection condition and/or the slide 110 satisfying the second detection condition is in a horizontal state, then the horizontal state is the receiving state, and when the slide 110 satisfying the first detection condition and/or the slide 110 satisfying the second detection condition needs to be transferred from the receiving member 1722, the second transfer driving mechanism 1723 drives the slide 110 satisfying the first detection condition and/or the slide 110 satisfying the second detection condition to move from the horizontal state to the vertical state, then the vertical state is the gripping state.
Further, the sample processing device 10 of the present embodiment further includes a staining unit 18, where the staining unit 18 is configured to stain a slide, and if the first detection condition is a qualification standard, the staining unit 18 is configured to stain a slide 110 that meets the qualification standard and is coated with a sample.
Referring to fig. 6 and 11, fig. 11 is a schematic perspective view of the staining unit 18 and the gripping unit 21 in fig. 2. The sample processing apparatus 10 of the present embodiment further includes a second detection unit 19, where the second detection unit 19 is configured to detect whether the stained slide meets the staining condition.
Wherein the second detecting unit 19 is used for detecting at least one of whether the dyeing quality of the slide after the dyeing is finished is qualified, whether the number of samples on the slide is qualified, and whether the transmittance of the slide is qualified.
In an embodiment, the slide printing unit 11 is further configured to perform slide printing on a slide that satisfies the dyeing condition and/or does not satisfy the dyeing condition, so as to form a second detection mark on the slide that satisfies the dyeing condition and/or does not satisfy the dyeing condition, that is, after the second detection unit 19 finishes detecting, if the second detection mark needs to be formed, the slide 110 after the completion of dyeing is returned to the slide printing position P1, so that the slide printing unit 11 performs slide printing on the slide that satisfies the dyeing condition and/or does not satisfy the dyeing condition, thereby distinguishing the slide that satisfies the dyeing condition and/or does not satisfy the dyeing condition.
In another embodiment, the sample processing apparatus 10 further includes a staining printing unit 20, and the staining printing unit 20 is configured to print a slide that satisfies the staining condition and/or does not satisfy the staining condition to form a second detection mark on the slide that satisfies the staining condition and/or does not satisfy the staining condition, so as to distinguish the slide that satisfies the staining condition and/or does not satisfy the staining condition.
Further, the sample processing apparatus 10 in this embodiment further includes a clamping unit 21, the clamping unit 21 includes a clamping driving mechanism 211 and a clamping assembly 212, the clamping driving mechanism 211 is connected with the clamping assembly 212 to drive the clamping assembly 212 to move, a clamping position P7, a staining position P8 and a second detection position P9 are respectively provided along a movement track of the clamping assembly 212, the clamping assembly 212 is used for clamping a slide at the clamping position P7, the staining unit 18 is used for staining the slide at the staining position P8, and the second detection unit 19 is used for detecting whether the stained slide meets a staining condition at the second detection position P9.
Specifically, the clamping driving mechanism 211 drives the clamping assembly 212 to move to the clamping position P7, so that the clamping assembly 212 clamps the slide of the sample processing apparatus 10 that completes the slide pushing operation, in this embodiment, the clamping assembly 212 clamps the slide coated with the sample from the receiving piece 1722, and then the clamping driving mechanism 211 drives the clamping assembly 212 to move the slide to the staining position P8, and after the staining is completed, the clamping driving mechanism 211 drives the clamping assembly 212 to move the slide to the second detection position P9, so that the second detection unit 21b detects whether the slide meets the staining condition.
In the above-described embodiment, the gripping driving mechanism 211 is used to drive the gripping assembly 212 to return the slide that satisfies the dyeing condition and/or does not satisfy the dyeing condition to the gripping position P7, that is, when the second detection unit 21b finishes detecting, the gripping driving mechanism 211 drives the gripping assembly 212 to return the slide from the second detection position P9 to the gripping position P7, so that the slide that satisfies the dyeing condition and/or does not satisfy the dyeing condition is returned to the slide printing position P1 by the conveying unit 14 of the sample processing apparatus 10, thereby causing the slide printing unit 11 to print the slide that satisfies the dyeing condition and/or does not satisfy the dyeing condition to form the second detection mark on the slide that satisfies the dyeing condition and/or does not satisfy the dyeing condition.
In the above-mentioned another embodiment, the second printing position P10 is further provided along the movement track of the gripping assembly 212, and the staining printing unit 20 is configured to perform slide printing on the slide that satisfies the staining condition and/or does not satisfy the staining condition at the second printing position P10, that is, when the second detection unit 19 detects that the second detection unit 19 is complete, the gripping driving mechanism 211 drives the gripping assembly 212 to move the detected slide to the second printing position P10, so that the staining printing unit 20 performs slide printing on the slide that satisfies the staining condition and/or does not satisfy the staining condition.
In this embodiment, although the specific structures of the second detection unit 19 and the dye printing unit 20 are not shown, it is understood that the dye printing unit 20 is the same as the slide printing unit 11 described above, and the second detection unit 19 and the first detection unit 13 differ only in terms of detection items thereof, so that the description of the embodiment of the sample processing apparatus 10 may be referred to with respect to the specific structures of the second detection unit 19 and the dye printing unit 20, and the specific installation positions of the two may be determined according to the actual situation, which is not limited.
Unlike the prior art, the sample processing apparatus provided in the embodiment of the present application includes: the slide printing unit is used for performing slide printing on the slide according to the user identity information of the sample so as to form a user identity mark on the slide; a processing unit for processing a sample on the slide; the first detection unit is used for detecting whether the slide meets detection conditions or not, so that the slide printing unit prints the slide meeting the first detection conditions and/or the slide meeting the second detection conditions to form a first detection mark on the slide meeting the first detection conditions and/or the slide meeting the second detection conditions, and therefore the slide meeting the first detection conditions and/or the slide meeting the second detection conditions can be distinguished through the first detection mark.
The foregoing is only a part of the embodiments of the present application, and is not intended to limit the scope of the present application, and all equivalent devices or equivalent process transformations made by using the descriptions and the contents of the present application, or direct or indirect application to other related technical fields, are included in the scope of patent protection of the present application.

Claims (10)

1. A sample processing device, the sample processing device comprising:
the slide printing unit is used for performing slide printing on the slide according to the user identity information of the sample so as to form a user identity mark on the slide;
a processing unit for processing a sample on the slide;
and the first detection unit is used for detecting whether the slide meets detection conditions or not, so that the slide printing unit prints the slide meeting the first detection conditions and/or the slide meeting the second detection conditions to form a first detection mark on the slide meeting the first detection conditions and/or the slide meeting the second detection conditions.
2. The apparatus according to claim 1, wherein the processing unit is configured to apply a sample onto the slide, the apparatus further comprises a conveying unit including a conveying carrier mechanism configured to carry the slide and a conveying drive mechanism connected to the conveying carrier mechanism to drive the conveying carrier mechanism to move, slide printing positions and first detection positions are provided along a movement locus of the conveying carrier mechanism, respectively, the slide printing unit is configured to slide-print the slide at the slide printing positions, and the first detection unit is configured to detect whether the slide satisfies a detection condition at the first detection positions;
the processing unit is used for coating a sample on the slide at the first detection position; or (b)
And a slide pushing position is further arranged along the motion track of the conveying bearing mechanism, and the processing unit is used for coating the sample on the slide at the slide pushing position.
3. The sample processing apparatus according to claim 2, wherein the transport driving mechanism is configured to drive the transport carriage mechanism to sequentially move the slide to the slide printing position and the first detection position so that the slide printing unit performs first slide printing on the slide at the slide printing position according to user identification information of a sample, and after detection by the first detection unit is completed, the transport driving mechanism drives the transport carriage mechanism to return the slide to the slide printing position so that the slide printing unit performs second slide printing on the slide satisfying a first detection condition and/or the slide satisfying a second detection condition at the slide printing position.
4. The sample processing apparatus of claim 2, wherein the slide printing station comprises a first printing station and a second printing station, the slide printing unit comprises a first printing module and a second printing module, the transport drive mechanism is configured to drive the transport carriage mechanism to sequentially move the slide to the first printing station and the first detection station, such that the first printing module prints the slide for a first time at the first printing station according to user identity information of a sample, and after detection by the first detection unit is completed, the transport drive mechanism drives the transport carriage mechanism to move the slide to the second printing station, such that the second printing module prints the slide satisfying a first detection condition and/or the slide satisfying a second detection condition for a second time.
5. A slide pushing device according to claim 2, wherein the slide printing unit is configured to perform a first slide printing on the slide according to user identification information of a sample, the processing unit is configured to apply the sample on the slide after the first slide printing to form a smear, the first detection unit is configured to detect whether the smear satisfies a detection condition, and the slide printing unit is configured to perform a second slide printing on the smear satisfying a first detection condition of a qualification standard and/or the smear satisfying a second detection condition.
6. The apparatus according to claim 2, wherein the slide printing unit is configured to perform a first slide printing on the slide according to user identification information of a sample, the first detection unit is configured to detect whether the slide after the first slide printing satisfies a detection condition, the slide printing unit is configured to perform a second slide printing on the slide satisfying the first detection condition and/or the slide satisfying a second detection condition, and the processing unit is configured to apply the sample on the slide after the second slide printing.
7. The sample processing device of claim 2, wherein said first detection unit is configured to detect whether said sample meets at least one of a slide pushing condition, whether said processing unit is operating properly, and whether a sample coated on said slide meets a coating criterion.
8. The sample processing device of claim 1, further comprising a staining unit for staining the slide.
9. The sample processing device according to claim 8, further comprising a second detection unit for detecting whether or not the stained slide satisfies a staining condition;
the slide printing unit is also used for performing slide printing on the slide meeting the dyeing condition and/or not meeting the dyeing condition so as to form a second detection mark on the slide meeting the dyeing condition and/or not meeting the dyeing condition; or (b)
The sample processing apparatus further includes a staining printing unit for performing slide printing on a slide that satisfies and/or does not satisfy the staining condition to form a second detection mark on the slide that satisfies and/or does not satisfy the staining condition.
10. The sample processing device according to claim 9, wherein the second detection unit is configured to detect at least one of whether a staining quality of a stained slide is acceptable, whether the number of samples on the slide is acceptable, and whether a transmittance of the slide is acceptable.
CN202211622018.6A 2022-12-16 2022-12-16 Sample processing equipment Pending CN116380903A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202211622018.6A CN116380903A (en) 2022-12-16 2022-12-16 Sample processing equipment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202211622018.6A CN116380903A (en) 2022-12-16 2022-12-16 Sample processing equipment

Publications (1)

Publication Number Publication Date
CN116380903A true CN116380903A (en) 2023-07-04

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202211622018.6A Pending CN116380903A (en) 2022-12-16 2022-12-16 Sample processing equipment

Country Status (1)

Country Link
CN (1) CN116380903A (en)

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