CN116370836A - Method and device for improving eyesight by low-energy red light self-adaptive radiation type polarized irradiation - Google Patents

Abstract

The invention relates to a method and a device for improving vision by irradiating fundus with low-energy red light self-adaptive polarization state adjustment. The incident light of this method is a parallel red polarized light beam, which is generated by natural light through a compound linear polarizer to form a radiation-type linearly polarized light, and irradiates the retinal area with the optic disc as the center, so that each linear polarization direction is along the direction of the retina. Collagen fibers diverge. Due to individual differences, the present invention introduces an optic disc imaging positioning system to adjust the central position of the radiation linearly polarized beam so that it is located in the center of the optic disc, so that the divergent radiation direction of the linearly polarized light fits the direction of the retinal collagen fiber cells to achieve better stimulation irradiation treatment effect.

Description

A method for improving eyesight by adaptive radiation polarized irradiation of low-energy red light and its device

technical field

The invention relates to the field of recovery and treatment of visual function, in particular to a method and a corresponding device for improving eyesight by using low-energy red light adaptive radiation polarization adjustment to irradiate the fundus.

Background technique

Vision improvement technology has become a hot topic in medical research today, among which low-energy red light irradiating the fundus to improve vision is an effective treatment method, which can improve vision and symptoms of eye diseases such as blurred vision, and is currently being used in the treatment of myopia have an important position. Studies have shown that low-energy red light can improve the metabolism of retinal cells, stimulate cone cells, improve the oxygen-carrying capacity of red blood cells, strengthen the central fixation function of the macula, and promote the regeneration of retinal cells, thereby improving vision. At present, low-energy red light therapy has been widely used in the treatment of fundus diseases, such as macular degeneration, glaucoma, cataract and other diseases.

Based on the principle of red light therapy, the present invention proposes a therapy and a device that introduces low-energy red light in a radially polarized state and irradiates the retina with the optic disc as the center, so as to improve eyesight more effectively. Polarized red light is a special kind of red light in which the electric field vector in the electromagnetic wave is vibrated in a specific direction. Polarized red light exposure increases collagen content compared to natural light stimulation (Silva.D.F 2006, Journal of Biomedical Optics), thereby improving eyeball elasticity and toughness. In particular, laser irradiation can also increase the strength of corneal collagen fibers (S.E.Avetisov 2013, Journal of Biomedical Optics). When the polarization direction is irradiated along the fiber direction, it is more conducive to stimulating the activity of fiber cells (Ando2013, Journal of Biomedical Optics), which promotes the cone Rod cells, glial cells and polar cells (HulyarSO, 2015Medical Informatics and Engineering), and can significantly enhance retinal activity, thereby accelerating the repair of damaged retina. Since the nerve fibers diverge from the optic disc (optic papilla) as the center, the present invention uses radially polarized red light to better align the polarization direction with the direction of optic neuron fibers, ensuring both the irradiation intensity and the therapeutic effect. At the same time, due to individual differences, linear polarization imaging technology is used for positioning, and the central position of the radiating linearly polarized beam is adjusted so that the divergent radiation direction of the linearly polarized light fits the direction of the retinal collagen fiber cells, so as to achieve a better stimulation irradiation treatment effect.

Contents of the invention

A low-energy red light self-adaptive polarization state adjustment method and device for illuminating the fundus to improve eyesight, characterized in that the red light is modulated to have radiative linear polarization characteristics while the parallel red light beam is irradiating the eye for treatment. Using linear polarization imaging technology to image the fundus retina to locate the position of the optic disc, adjust the center position of the above-mentioned radially polarized parallel light beam entering the pupil, so that it can irradiate more effectively along the divergent direction of optic nerve collagen fibers around the optic disc, and stimulate deeper fundus tissue, thereby It has a better vision improvement effect.

The device of the present invention includes an emission source, which is a red light LED or a red light laser source; a radiation type linear polarization polarizing device, which is composed of linear polarization sector plates with the same radius and small arc, and the sector plate linear polarization directions are all along the Radial, thus producing a radiative linearly polarized beam; a rotatable wheel, on which there is a linear polarizer and a light intensity attenuator, whose function is to change the linearly polarized light in the above radiation into a single direction linearly polarized light and Switch between radiative linearly polarized light beams; a fundus imaging system, which is composed of a linear polarizer, a two-dimensional imaging detector and a processing unit; The system is a two-dimensional translation system that can translate simultaneously, which can be controlled by two micro-motor units; a light intensity regulator that controls light intensity, and its main component is a gradually changing light intensity attenuation sheet.

Method of the present invention comprises the following steps:

(1) The system receives a signal to start working, and the red light source, the rotatable wheel, the fundus imaging system, and the light intensity regulator start to work;

(2) As shown in Figure 1, the red light source 1 emits a parallel light beam 2, which passes through the radiation type linear polarization polarizer 3 to form radiation type parallel red light with linearly polarized light in all directions on the cross section. The traveling direction of the polarized parallel red light is obliquely incident downward at a certain small angle with the central axis 4. The reason for the oblique incident is that the center of the optic disc of the retina is located below the midline of the eye axis physiologically;

(3) The rotatable wheel 5 adjusts the linear polarizer 6, so that the radiation linearly polarized light becomes linearly polarized light in a single direction to pass through;

(4) Fundus imaging system linear polarizer 7 and two-dimensional area array detector 8 and red light source are symmetrically obliquely incident and received with respect to the center of the eye axis, and the single linearly polarized parallel red light generated in steps (2) and (3) is used as The incident light source, the reflected light returned on the retina passes through the linear polarizer 8 of the imaging system. The linear polarizer 8 is perpendicular to the vibration direction of the polarizer 6 in step (3), and finally forms a fundus image on the two-dimensional detector 9 . Since the optic disc is isotropic and other areas are anisotropic, a white spot will appear in the image;

(5) According to the detected image of step (4), utilize the two-dimensional translation system 10 to translate the entire device, and the device is adaptively moved, so that the white spots are moved to the center of the image, that is, the center of the light beam just irradiates on the optic disc 11;

(6) The rotatable wheel can be adjusted to the light intensity attenuation sheet 6 to allow the radiation linearly polarized light to pass through. According to the adjustment of steps (4) and (5), the center of its radiated linearly polarized light is better irradiated on the optic disc 11, and the direction of linearly polarized light fits with the direction of peripheral visual fiber;

(7) After the aforementioned steps (1)-(6), the eyes are irradiated for 3 minutes, and one treatment is completed, and the treatment is performed twice a day.

Compared with prior art, the beneficial effect of the present invention is:

(1) The present invention uses low-energy red light with a specific polarization state, which will not cause obvious damage or discomfort to the eyes. Its characteristic is that the radiation-type linear polarization processing is adopted for the incident into the pupil, and the divergent linear polarization direction centered on the optic disc better fits the direction of optic neuron fibers, which can more effectively stimulate the tissue of the fundus, improve mitochondrial activity and neurons. cell growth. This method is a non-invasive treatment method, which not only ensures the irradiation intensity of red light but also improves the treatment effect.

(2) The present invention introduces the retinal optic disc imaging positioning system, obtains the relative position of the divine disc on the image with a linear polarization orthogonal imaging system, and the incident light can adaptively adjust the incident plane position, so that the radial polarization center of the light beam is located near the optic disc . This ensures that the direction of the incident radiant linearly polarized light and the optic nerve collagen fibers around the optic disc can be well matched and coincident, and the precise positioning and adjustment of the radiant linearly polarized light beam can be realized, and the accuracy and effectiveness of the treatment can be improved, so as to achieve better treatment. treatment effect.

Description of drawings

Fig. 1 is a schematic structural diagram of a system device of the present invention;

Fig. 2 is a structural schematic diagram of a radiating linear polarizer of the present invention;

Fig. 3 is the schematic diagram of embodiment device of the present invention;

Fig. 4 is a flowchart of the steps of the embodiment of the present invention.

Detailed ways

The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

Fig. 1 is a schematic diagram of the structure of the system device of the present invention, which includes the following devices: a red light source 1, which is a red light LED or a laser source, and the light source emits a parallel light beam 2. The radial linear polarizing polarizer 3 is composed of spliced linear polarizing sector plates with the same radius and small arc, and the linear polarization directions of the sector plates are all along the radial direction, thereby generating a radial linearly polarized light beam. The device also includes a central axis 4 and a rotatable wheel 5 . The polarized parallel light beam will be irradiated vertically to the eye cells 5 through the light guide tube.

Fig. 2 is a schematic diagram of the structure of the radiating linear polarizing film of the present invention. The radiating linear polarizing film 1 is composed of linear polarizing sectoral plates 2 with the same radius and small arc. beam.

An embodiment of the present invention will be further described below in conjunction with the accompanying drawings.

Fig. 3 is a schematic diagram of a device according to an embodiment of the present invention, specifically an example of a low-energy red light self-adaptive radiation-type polarized-irradiation fundus vision-improving device. Described device has five parts, and light source part adopts 630nm laser light source 1 and beam expander mirror 2, and polarization adjusting device is made up of a radiation type linear polarizer 3 and rotatable wheel disc 4 (by linear polarizer 5 and light intensity regulator 6 is a gradual light intensity attenuation film), the fundus imaging system is composed of a linear polarizer 7 and an area array CCD (including an imaging processing unit) 8, and the two-dimensional translation system is composed of two one-dimensional translation stages.

Fig. 4 embodiment step flow chart of the present invention, concrete implementation steps are:

(1) After the system receives the signal and starts to work, the 630nm laser light source 1 emits 5mW of laser light, and passes through the laser beam expander 2 to produce a parallel beam with a cross-sectional diameter of 10mm. At the same time, the rotating wheel 4, the fundus imaging system line polarizer 7 and The power supply of area array CCD8 and light intensity regulator 6 starts to start.

(2) For the light beam formed from step (1), make its travel direction be obliquely incident at a certain small angle of 20 degrees above the central axis 10 of the eyeball, so that it can better approach the retina at the correct position disc center;

(3) the light beam in the step (2) is passed through the radiating linear polarizer 3 in the polarization adjustment device to form a radiating polarized parallel red light with linearly polarized light in all directions on the cross section;

(4) Pass the radiative polarized parallel red light in the step (3) through the rotatable wheel 4 in the polarization adjustment device, and rotate the wheel to the linear polarizer 5 by the rotating device, and the vibration direction of the linear polarizer is the horizontal direction;

(5) The fundus imaging system is below the central axis of the eye axis, and the placement angle is axisymmetric to the light source. Rotate the linear polarizer 7 in the fundus imaging system to a vertical angle so that it is in line with the linear polarizer in step (4). 3 The included angle is 90 degrees;

(6) By the incident light of step (4) and step (5) forming the imaging optical path to the reflected light, the fundus image is formed on the area array CCD8. On the image, because the optic disc is isotropic and other regions are anisotropic, its image A white spot will form at the

(7) In the image of step (6), the white spot contrast is the lowest, and the processing unit will be used to calculate the white spot center position coordinates;

(8) Reversely move the two-dimensional translation device 9 according to the coordinate value of step (7), so that the white spot is located at the center of the image, and complete the positioning of the center of the light beam to the optic disc

(9) Rotate the rotatable wheel 4 in the polarization adjustment device in step (4) to the light intensity attenuator 6 through the rotating device, so that the radiative linearly polarized beam can pass through;

(10) The parallel linearly polarized red light with a cross section of 10mm is normal incident into the pupil, completely covering the pupil area.

(11) After the aforementioned steps (1)-(5) irradiate for 3 minutes, one treatment is completed, and the treatment is performed twice a day.

Claims (9)

1. The device for improving vision by adjusting irradiation fundus of low-energy red light adaptive polarization state is characterized by comprising an emission source which is a red light LED or a red light laser source; a radial linear polarization polarizer; a rotatable wheel; a fundus imaging system; a two-dimensional translation system; a light intensity regulator for controlling light intensity is composed of a gradually-changed light intensity attenuation sheet.

2. The radiation type linear polarization device according to claim 1, wherein the device is formed by splicing fan-shaped linear polarizers with small radian of same radius, and the linear polarization directions of the fan-shaped polarizers are all along radial direction, so as to generate radiation type linear polarized light beams.

3. A rotatable wheel according to claim 1 having a linear polarizer and light intensity attenuator thereon operative to switch between converting said radiation into single direction linear polarized light and radiation-type linear polarized light by rotation.

4. The fundus imaging system according to claim 1, comprising a linear polarizer, a two-dimensional imaging detector and a processing unit.

5. The two-dimensional translation system according to claim 1, wherein said radial linear polarization polarizer, said rotatable wheel and said fundus imaging system are simultaneously translatable.

6. A method for improving vision by illuminating fundus with low energy red light adaptive polarization adjustment, said method comprising the steps of:

(1) The system starts to work, and a red light source, a rotatable wheel disc, a fundus imaging system and a light intensity regulator are started;

(2) The red light source emits parallel light beams, and the light beams pass through the radiation type linear polarization device;

(3) The rotary wheel disc can be used for adjusting the linear polarizing plate to change the radiation linear polarized light into single-direction linear polarized light to pass through;

(4) The fundus imaging system receives the single linearly polarized parallel red light generated in the steps (2) and (3) as an incident light source and forms a fundus image;

(5) Translating the whole device by using a two-dimensional translation system according to the detection image in the step (4);

(6) The rotary wheel disc adjusts the light intensity attenuation sheet to enable the radiation linear polarized light to pass through, and according to the adjustment of the steps (4) and (5), the center of the radiation linear polarized light well irradiates the optic disc, and the direction of the linear polarized light is attached to the direction of peripheral optic fibers.

7. The method according to claim 6, wherein the radiation type linear polarization polarizing device in the step (2) forms radiation type parallel red light with linearly polarized light in all directions on a cross section, and the polarized parallel red light forms an included angle with a central axis by a certain small angle and is obliquely incident downwards.

8. The method according to claim 6, wherein in the step (4), the linear polarizer and the two-dimensional area array detector of the fundus imaging system are symmetrical to the red light source about the center of the eye axis, the single linear polarization parallel red light incident light source generated in the oblique incidence receiving steps (2) and (3) is used, the reflected light returned on the retina passes through the linear polarizer of the imaging system, the linear polarizer is perpendicular to the vibration direction of the polarizer in the step (3), and the fundus image is finally formed on the two-dimensional detector.

9. The method for improving vision by adjusting illumination fundus with low-energy red light adaptive polarization according to claim 6, wherein the detected image in step (5) is translated through a two-dimensional translation system to adaptively move the device so that white spots are moved to the center of the image, i.e. the center of the light beam is just illuminated on the optic disc.

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