CN115813011A - Preparation method and application of atomized liquid containing theanine - Google Patents

Abstract

The invention discloses a preparation method and application of an atomized liquid containing theanine, belonging to the technical field of atomized liquids, and the preparation method comprises the following steps: 1) Adding an organic acid A into a solvent, and heating and dissolving to obtain a dissolved solution; 2) Sequentially adding nicotine and theanine into the dissolved solution, heating and stirring to obtain a mixed solution; 3) And adding the organic acid B into the mixed solution, heating and stirring to obtain nicotine salt, and preparing the nicotine salt into the electronic cigarette atomized liquid according to the requirements of smoking utensils. The theanine serving as an additive for improving the mouthfeel of tobacco products can reduce the spicy stimulation of nicotine in the application of the electronic cigarette atomized liquid, makes the oral cavity fresh, improves the physiological activity of people, reduces the excessive dependence on nicotine, and has a health-care effect.

Description

A preparation method and application of an atomized liquid with theanine

technical field

The invention relates to the technical field of atomized liquid, and belongs to an additive for cigarettes, in particular to a preparation method and application of an atomized liquid with theanine.

Background technique

According to the data of the 2021 World Tobacco Development Report, the global non-cigarette tobacco products are accelerating the pace of development. Judging from the changing trend of consumer demand, although the expansion space of the world cigarette market is gradually shrinking, the market space of non-cigarette tobacco products is still very broad. Whether e-cigarettes are used for smoking cessation or as substitutes for traditional cigarettes, there is huge room for growth.

As a substitute for smoking cessation and traditional cigarettes, electronic cigarettes contain nicotine, the main physiologically active substance in tobacco. By smoking e-cigarettes, consumers can obtain nicotine intake, thereby obtaining the same physiological satisfaction as smoking cigarettes. However, the low-concentration nicotine electronic cigarettes stipulated by the national standard are difficult to achieve the physiological satisfaction of old smokers, and nicotine is a spicy and irritating substance, which is harmful to human health and has strong addiction; another On the one hand, in an essential sense, electronic cigarettes are still a tobacco product that is harmful to health and one of the substitutes for traditional tobacco product cigarettes.

The current method is usually to increase the amount of nicotine to achieve the satisfaction needed to relieve addiction. Increase the amount of nicotine, although reached the sense of satisfaction, the use of nicotine is too large, the cost is on the high side, and the stimulation of high content nicotine to oral cavity and the injury to human body all increase again in addition.

Contents of the invention

Aiming at the problem that the nicotine in the national standard electronic cigarette is too low to achieve satisfaction and smokers are addicted to nicotine, the purpose of the present invention is to provide a preparation method and application of an atomized liquid with theanine. The purpose is to provide the application of theanine in e-cigarette liquid. As an additive to improve the taste of tobacco products, theanine can reduce the pungent stimulation of nicotine in the application of e-cigarette liquid, refresh the mouth and improve human physiological activity, reduce excessive dependence on nicotine, and have health care effects.

To achieve the above object, the present invention provides the following technical solutions:

A preparation method of an atomized liquid with theanine, the steps are as follows:

1) adding the organic acid A into the solvent, heating and dissolving to obtain a solution;

2) sequentially adding nicotine and theanine into the solution, heating and stirring to obtain a mixed solution;

3) Add organic acid B to the mixed solution, heat and stir to obtain nicotine salt, and prepare the nicotine salt into an electronic cigarette liquid according to the requirements of smoking equipment.

As a further solution of the present invention, in step 3), the e-cigarette liquid is prepared by adding nicotine salt to the raw material and method of e-cigarette liquid.

The e-cigarette liquid prepared in step 3) is loaded into the same pod equipment, and a number of professional testers conduct sensory analysis for sensory analysis.

As a further solution of the present invention, in the prepared electronic cigarette liquid, the content of theanine is 2-20 mg/g.

As a further solution of the present invention, in the prepared electronic cigarette liquid, the content of theanine is 5-15 mg/g.

As a further solution of the present invention, in the prepared electronic cigarette liquid, the content of nicotine is 5-20 mg/g.

As a further solution of the present invention, in the prepared electronic cigarette liquid, the content of nicotine is 5-10 mg/g.

As a further solution of the present invention, the organic acid A is at least two of benzoic acid, dihydroxybenzoic acid, vanillic acid, cinnamic acid, nicotinic acid, salicylic acid, sorbic acid, levulinic acid, and lactic acid; The organic acid B is one of malic acid, citric acid and tartaric acid.

As a further solution of the present invention, the malic acid includes racemic malic acid, D-malic acid, and L-malic acid, and the tartaric acid includes racemic tartaric acid, D-tartaric acid, and L-tartaric acid.

The organic acids used in the electronic smog liquid of the present invention are a variety of organic acids as the main acid, one acid as the auxiliary acid, organic acid A as the main acid, and organic acid B as the auxiliary acid.

As a further solution of the present invention, the solvent is one or more of food-grade glycerin, food-grade ethanol, and food-grade propylene glycol.

As a further solution of the present invention, the heating temperature from step 1) to step 3) is 70-80°C, the heating time of step 1) is 15-30 min, and the heating time of step 2) and step 3) is 15-60 min .

An application of the e-cigarette liquid prepared by the above-mentioned method for preparing the atomized liquid with theanine in a pod device.

Compared with prior art, the beneficial effect of the present invention is:

1. The invention innovatively uses theanine to replace part of nicotine, reduces the amount of nicotine used to achieve the purpose of harm reduction, reduces dependence on nicotine, and improves the taste of electronic cigarettes to a certain extent.

2. The present invention aims at providing the application of theanine in the liquid of electronic cigarettes, and theanine can be used to improve tobacco The additive for the taste of the product can reduce the pungent stimulation of nicotine in the application of electronic cigarette liquid, refresh the mouth, improve human physiological activity, reduce excessive dependence on nicotine, and have health care effects.

3. The present invention provides the application of theanine in electronic cigarette liquid. The application is to use theanine as a nicotine substitute and an additive to improve the taste of electronic cigarettes in the preparation of electronic cigarette liquid.

Description of drawings

Fig. 1 is a schematic diagram of obtaining a yellow oily liquid in Example 1 of the invention and configuring it into an A1 electronic cigarette liquid.

Fig. 2 is a schematic diagram of replacing theanine with nicotine of equal mass in the invention example 1 to obtain a B1 electronic cigarette liquid without theanine.

Fig. 3 is a schematic diagram of obtaining a yellow oily liquid in Example 2 of the invention and configuring it into an A2-type electronic cigarette liquid.

Fig. 4 is a schematic diagram of replacing theanine with nicotine of equal mass in invention example 2 to obtain a B2 electronic cigarette liquid without theanine.

Fig. 5 is a schematic diagram of obtaining a yellow oily liquid in Example 3 of the invention and configuring it into an A3-type electronic cigarette liquid.

Fig. 6 is a schematic diagram of replacing theanine with an equal mass of nicotine in Example 3 of the invention to obtain a B3 electronic cigarette liquid without theanine.

Fig. 7 is a schematic diagram of obtaining a yellow oily liquid in Example 4 of the invention and configuring it into an A4 electronic cigarette liquid.

Fig. 8 is a schematic diagram of replacing theanine with an equal mass of nicotine in Example 4 of the invention to obtain a B4 electronic cigarette liquid without theanine.

Fig. 9 is a schematic diagram of obtaining a yellow oily liquid in Example 5 of the invention and configuring it into an A5-type electronic cigarette liquid.

Fig. 10 is a schematic diagram of replacing theanine with nicotine of equal mass in Example 6 of the invention to obtain a B5 electronic cigarette liquid without theanine.

Fig. 11 is a schematic diagram of obtaining a yellow oily liquid in Example 6 of the invention and configuring it into an A6 electronic cigarette liquid.

Fig. 12 is a schematic diagram of replacing theanine with nicotine of equal mass in Example 6 of the invention to obtain a B6 electronic cigarette liquid without theanine.

Detailed ways

The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only some of the embodiments of the present invention, but not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

Because nicotine enters the brain through the respiratory system and blood, binds to the nicotine acetylcholine receptor, and increases this receptor. Over time, people will become more and more dependent on the pleasure brought by smoking, which is nicotine addiction. It has been reported that nicotine acetylcholine receptors can also bind to theanine to relax the mind, and theanine has neuroprotective effects.

Among them, L-Theanine (L-Theanine) is a unique free amino acid in tea, it is glutamic acid γ-ethylamide, it is a white needle-like body, easily soluble in water, theanine has a sweet and refreshing taste , is the main component of the body fluid and sweetness in tea.

Studies have found that theanine can inhibit the binding of nicotine to nicotine acetylcholine receptors, and the nicotine acetylcholine receptors prefer to bind to theanine, resulting in the same pleasure as smoking. Therefore, theanine can significantly reduce people's excessive dependence on nicotine .

Aiming at the problem that the nicotine in the national standard e-cigarette is too low to achieve satisfaction and the smokers are addicted to nicotine, the purpose of the present invention is to provide the application of theanine in the e-cigarette liquid, theanine as an improvement The additive for the taste of tobacco products can reduce the pungent stimulation of nicotine in the application of electronic cigarette liquid, refresh the mouth, improve human physiological activity, reduce excessive dependence on nicotine, and have health care effects.

The technical solutions of the present invention will be further described in detail below in conjunction with specific embodiments.

Example 1

A preparation method of an atomized liquid with theanine, comprising the following steps:

Add 1.8g of benzoic acid and 1.3g of levulinic acid into 15g of glycerol, heat to dissolve at 75°C, add 3g of nicotine and 2g of theanine, heat at 75°C and stir for 30min to obtain a mixed solution; then add 0.2g of malic acid, 75 ℃ heating and stirring to obtain a yellow oily liquid, as shown in Figure 1; configure A1 electronic cigarette liquid according to the requirements of the smoking set.

Repeat the above process and replace the above-mentioned theanine with nicotine of the same quality to obtain the type B1 e-cigarette liquid without theanine, as shown in Figure 2.

The e-cigarette liquid is loaded into the pod device, and a number of professional evaluation personnel conduct sensory analysis. After comparing the above two e-cig liquids, it is found that the taste of the A1 type e-cig liquid has improved to a certain extent, and the nicotine Pungency and irritation are reduced, the taste is soft and delicate, and there is basically no miscellaneous taste. The throat hit and satisfaction are slightly lower than those of B1 electronic cigarette liquid, but the difference is not much different.

Example 2

A preparation method of an atomized liquid with theanine, comprising the following steps:

Add 1.9g of benzoic acid and 1.4g of fumaric acid to 15g of glycerin, heat to dissolve at 75°C, add 3.2g of nicotine and 1.8g of theanine, heat at 75°C and stir for 30min to obtain a mixed solution; then add 0.2g of malic acid , heated and stirred at 75°C to obtain a yellow oily liquid, as shown in Figure 3; configure it into an A2 electronic cigarette liquid according to the requirements of the smoking set.

Repeat the above process and replace the above-mentioned theanine with nicotine of the same quality to obtain a B2 electronic cigarette liquid without theanine, as shown in Figure 4.

The e-cigarette liquid is loaded into the pod device, and a number of professional evaluation personnel conduct sensory analysis. After comparing the above two e-cigarette liquids, it is found that the taste of the A2 type e-cigarette liquid has improved to a certain extent, and the nicotine content Spicy and irritating are both reduced, the taste is soft, and there are basically no miscellaneous smells. The throat hit and satisfaction are comparable to B2 electronic cigarette liquid.

Example 3

A preparation method of an atomized liquid with theanine, comprising the following steps:

Add 2.5g of benzoic acid and 0.4g of lactic acid into 15g of glycerin, heat to dissolve at 70°C, add 2.8g of nicotine and 2.2g of theanine, heat at 70°C and stir for 30min to obtain a mixed solution; then add 0.2g of malic acid, 70 ℃ heating and stirring to obtain a yellow oily liquid, as shown in Figure 5; according to the requirements of the smoking set, configure it into an A3 electronic cigarette liquid.

Repeat the above process and replace the above-mentioned theanine with nicotine of the same quality to obtain a B3 electronic cigarette liquid without theanine, as shown in Figure 6.

The e-cigarette liquid is loaded into the pod device, and a number of professional evaluation personnel conduct sensory analysis. After comparing the above two e-cig liquids, it is found that the taste of the A3 type e-cig liquid has improved to a certain extent, and the nicotine content The spiciness and irritation are reduced, the taste is soft, with a slight lactic acid aroma, and the throat hit and satisfaction are slightly lower than those of B3 electronic cigarette liquid, but the difference is not much different.

Example 4

A preparation method of an atomized liquid with theanine, comprising the following steps:

Add 2.0g of benzoic acid and 1.3g of vanillic acid into 15g of glycerin, heat to dissolve at 75°C, add 3.2g of nicotine and 1.8g of theanine, heat at 75°C and stir for 30min to obtain a mixed solution; then add 0.2g of malic acid, Heat and stir at 75°C to obtain a yellow oily liquid, as shown in Figure 7; configure it into an A4 electronic cigarette liquid according to the requirements of the smoking set.

Repeat the above process and replace the above-mentioned theanine with nicotine of the same quality to obtain the B4 electronic cigarette liquid without theanine, as shown in Figure 8.

The e-cigarette liquid is loaded into the pod device, and a number of professional testers conduct sensory analysis. After comparing the above two e-cig liquids, it is found that the taste of the A4 type e-cig liquid has improved to a certain extent, and the nicotine content The spiciness and irritation are reduced, the taste is soft, with a slight lactic acid aroma, and the throat hit and satisfaction are comparable to B4 electronic cigarette liquid.

Example 5

A preparation method of an atomized liquid with theanine, comprising the following steps:

Add 1.8g of benzoic acid and 1.2g of gentisic acid into 15g of glycerin, heat to dissolve at 75°C, add 2.9g of nicotine and 2.1g of theanine, heat at 75°C and stir for 30min to obtain a mixed solution; then add 0.2g of malic acid , heated and stirred at 75°C to obtain a yellow oily liquid, as shown in Figure 9; configure it into an A5 electronic cigarette liquid according to the requirements of the smoking set.

Repeat the above process and replace the above-mentioned theanine with nicotine of the same quality to prepare the B5 electronic cigarette liquid without theanine, as shown in Figure 10.

The e-cigarette liquid is loaded into the pod equipment, and a number of professional evaluation personnel conduct sensory analysis. After comparing the above two e-cig liquids, it is found that the taste of the A5 type e-cig liquid has improved to a certain extent, and the nicotine content The spiciness and irritation are reduced, the taste is soft, and there is basically no miscellaneous taste. The throat hit and satisfaction are slightly lower than those of the B5 electronic cigarette liquid, but the difference is not much different.

Example 6

A preparation method of an atomized liquid with theanine, comprising the following steps:

Add 1.7g of benzoic acid and 1.3g of gentisic acid into 15g of glycerin, heat to dissolve at 75°C, add 2.9g of nicotine and 2.1g of theanine, heat at 75°C and stir for 30min to obtain a mixed solution; then add 0.2g of malic acid , heated and stirred at 75°C to obtain a yellow oily liquid, as shown in Figure 11; configure it into an A6-type electronic cigarette liquid according to the requirements of the smoking set.

Repeat the above process and replace the above-mentioned theanine with nicotine of the same quality to obtain the B6 electronic cigarette liquid without theanine, as shown in Figure 12.

The e-cigarette liquid is loaded into the pod equipment, and a number of professional evaluation personnel conduct sensory analysis. After comparing the above two e-cigarette liquids, it is found that the taste of the A6 type e-cigarette liquid has improved to a certain extent, and the nicotine content Spicy and irritating are reduced, the taste is soft and delicate, basically no miscellaneous taste, and the throat hit and satisfaction are comparable to B6 electronic cigarette liquid.

Result analysis:

Based on the sensory evaluation results of Examples 1 to 6, it is shown that the e-cigarette liquid prepared by using theanine instead of nicotine has a soft and delicate mouthfeel and a good throat hit, which makes people feel pleasant and physiologically satisfied. The taste of the e-cigarette liquid without theanine is improved to a certain extent, the pungency and irritation of nicotine are reduced, the taste is soft and delicate, basically no miscellaneous taste, and there is no significant decrease in throat hit and satisfaction. To sum up, to a certain extent, theanine can be used in e-cigarette liquids to reduce the amount of nicotine used to achieve the purpose of harm reduction and reduce dependence on nicotine.

Therefore, the e-cigarette liquid prepared by the preparation method of an atomized liquid with theanine in the embodiment of the present invention innovatively uses theanine to replace part of nicotine, reducing the amount of nicotine used to achieve harm reduction The purpose is to reduce the dependence on nicotine and improve the taste of electronic cigarettes to a certain extent.

The preferred embodiments of the present invention have been described in detail above, but the present invention is not limited to the above-mentioned embodiments, and can also be made without departing from the gist of the present invention within the scope of knowledge possessed by those of ordinary skill in the art. Variations.

Claims (10)

1. A preparation method of an atomized liquid containing theanine is characterized by comprising the following steps:

1) Adding an organic acid A into a solvent, and heating for dissolving to obtain a dissolved solution;

2) Sequentially adding nicotine and theanine into the dissolved solution, heating and stirring to obtain a mixed solution;

3) And adding the organic acid B into the mixed solution, heating and stirring to obtain nicotine salt, and preparing the nicotine salt into the electronic cigarette atomized liquid according to the requirements of smoking utensils.

2. The method for preparing the atomized liquid containing theanine of claim 1, wherein the atomized liquid of electronic cigarette is prepared by adding nicotine salt into raw materials of electronic cigarette tobacco tar and the method in step 3).

3. The method for preparing an atomized liquid containing theanine as claimed in claim 1, wherein the content of theanine in the prepared atomized liquid of electronic cigarette is 2 to 20mg/g.

4. The method for preparing an atomized liquid containing theanine as claimed in claim 3, wherein the atomized liquid is formulated into an electronic cigarette atomized liquid, and the content of theanine is 5 to 15mg/g.

5. The method for preparing an atomized liquid containing theanine as claimed in claim 1, wherein the content of nicotine in the prepared atomized liquid of electronic cigarette is 5 to 20mg/g.

6. The method for preparing an atomized liquid containing theanine as claimed in claim 5, wherein the content of nicotine in the prepared atomized liquid containing electronic cigarette is 5 to 10mg/g.

7. The method for producing an atomized liquid having theanine according to claim 1, wherein the organic acid a is at least two of benzoic acid, dihydroxybenzoic acid, vanillic acid, cinnamic acid, nicotinic acid, salicylic acid, sorbic acid, levulinic acid, and lactic acid; the organic acid B is one of malic acid, citric acid and tartaric acid.

8. The method for preparing an atomized liquid containing theanine as set forth in claim 7, wherein the malic acid includes racemic malic acid, D-malic acid and L-malic acid, and the tartaric acid includes racemic tartaric acid, D-tartaric acid and L-tartaric acid.

9. The method of claim 1, wherein the solvent is one or more of food grade glycerol, food grade ethanol, and food grade propylene glycol.

10. Use of an electronic smoke aerosol prepared according to the method of preparing an aerosol with theanine of claims 1 to 9 in a cartomizer device.

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