CN115707399A - Composition containing tea extract and mogroside and atomizer - Google Patents

Abstract

The invention relates to an atomized composition containing tea extract and mogroside and an atomizer.

Description

Composition and atomizer containing tea extract and mogroside

technical field

The invention relates to the field of electronic atomization, in particular to a composition that can be used as an atomization liquid and an atomizer thereof.

Background technique

Tea consumption has been linked to the prevention and reduction of many serious health conditions, such as cancer, immune and cardiovascular diseases. The health benefits associated with tea consumption are mainly attributed to tea polyphenols and theanines. The functional properties of tea polyphenols are mainly anti-oxidation, anti-mutagenesis, anti-cancer, anti-microbial and so on. Tea pigment has also been proved to be an important bioactive component of tea, which has health functions such as anti-inflammation, anti-cancer and liver protection, but its antioxidant activity may be lower than that of catechin

Tea extract has good antioxidant activity, mainly because it has various antioxidant components such as scavenging free radicals, consuming ROS, increasing the content of antioxidant substances, and enhancing the activity of antioxidant enzymes.

Another class of substances with high content in tea extract is caffeine. The chemical name of caffeine is 1,3,7-trimethylxanthine. It is an important functional ingredient in tea, coffee and some functional drinks. It is also one of the most widely consumed daily dietary ingredients and psychotropic drugs in the world. one. In addition to improving the brain's memory and recognition ability and increasing the excitement of the nervous system, caffeine also has the characteristics of promoting insulin secretion and reducing the risk of type 2 diabetes. Its ingestion stimulates wakefulness and alertness, improves mood, and releases catecholamines, which can have beneficial effects on human behaviour. In addition, caffeine also has antioxidant and anti-inflammatory effects, which are extremely important for human health, and can alter cellular redox and inflammatory states in a dose-dependent manner. Caffeine intake has also been shown to have a good performance-enhancing effect, which is caused by different factors, such as enhanced substrate utilization and increased resistance to fatigue.

Mogroside is a sweetener extracted from Luo Han Guo, which has expectorant, antitussive, antibacterial, and anti-inflammatory effects. Existing research results have shown that mogroside can significantly reduce the number of coughs and increase the amount of tracheal secretions in mice. In addition, Luo Han Guo extract can also significantly reduce the number of coughs in guinea pigs caused by citric acid or capsaicin, prolong the cough latency, and inhibit the number of coughs in guinea pigs caused by mechanical stimulation.

It has been reported that tea extracts are used to prepare atomized liquids containing tea extracts, but the atomized liquids prepared solely using tea extracts have problems such as poor taste and low tea utilization rate. How to improve the utilization rate of tea and at the same time Products with rapid onset of action, ease of use, and good taste need to be further developed and researched.

Invention content:

The invention provides a composition containing tea extract and mogroside and an atomizer. The composition is formed by mixing tea extract and mogroside. The composition can be prepared as an atomized atomizer with tea aroma. liquid, the present invention further includes a matching atomizer.

The invention provides a composition comprising tea extract and mogroside.

A composition of the present invention, wherein the weight ratio of tea extract and mogroside is 1-25:1-10.

A composition of the present invention, wherein the weight ratio of tea extract and mogroside is 5-20:2-8.

A composition of the present invention, wherein the weight ratio of tea extract and mogroside is 8-15:3-6.

A composition of the present invention, wherein the weight ratio of tea extract and mogroside is 10-12:4-6.

A composition of the present invention, the tea extract is any kind of tea extract, such as the extract of green tea, black tea, black tea, oolong tea, yellow tea, white tea, Pu'er tea, preferably Pu'er tea.

The mogroside CAS of the present invention is 88901-36-4.

The extract is a product obtained by processing tea leaves through solvent immersion, decoction, ultrasonication, microwave, etc., and contains tea polyphenols and other ingredients. Taking the Pu’er tea extract as an example, the Pu’er tea extract is obtained by boiling or refluxing the Pu’er tea using a solvent containing water or ethanol, which is dissolved in the solvent. After boiling or refluxing for a period of time, the tea leaves can be extracted Tea polyphenols and other ingredients are extracted from tea leaves and dissolved or dispersed in a solvent, such as water or ethanol. The ingredients in the solvent and the solvent form a solution together. After the solution is concentrated, a fluid extract can be obtained. In addition, it can be prepared as required. Extractions with different relative densities can be dried to obtain dry extracts, and crushed if necessary to meet the requirements of the present invention.

Preferably, the extraction process of the Pu'er tea extract includes two steps. The first step is to use a solvent to extract and filter to obtain a solvent extract. The second step is to add water to the filtered filter residue and use ethanol for alcohol precipitation to obtain solution, the solvent extract and the alcohol precipitation solution are combined to form the Pu'er tea extract, which is then concentrated and dried to obtain the extract powder.

More preferably, described Pu'er tea extract, extraction process comprises two steps

In the first step, add 8-10 times the amount (bv) of the extraction solvent to the Pu’er tea leaves and decoct them for 2-3 times, each time for 0.5-1 hour, keep warm at 80-90°C during the extraction process, stir, filter the extract, and set aside;

The second step: add water to the filter residue obtained in the previous step and concentrate under reduced pressure (≤70°C) for extraction until tea (weight): concentrated solution (volume) = 1:2-1:3, after filtering the tea residue, the obtained concentrated solution is added Precipitate with ethanol until the ethanol concentration is 70-90%, let stand after cooling, and take the supernatant; mix the extract obtained in the first step with the supernatant obtained in the second step, then concentrate and dry;

Wherein the extraction solvent in the first step is preferably propylene glycol, more preferably propylene glycol added with water or ethanol, and the amount of water or ethanol added to the propylene glycol is 1-20% (volume ratio).

The present invention further provides an electronic atomization liquid, which contains the composition of the present invention.

The composition of the present invention includes tea extract and mogroside, and the two can be mixed in any ratio, preferably the above-mentioned ratio.

The composition can be in liquid state, solid state, or semi-solid state, and it can be prepared according to needs. The simplest preparation method is to mix the two.

The composition of the present invention can be sold as a commercial product, can be taken orally, and used intranasally. It is particularly preferred to prepare an aerosol and use the atomized liquid of the present invention, wherein the composition accounts for The weight ratio is: 1:1000～130:1000, preferably 1:81～1:101

An atomized liquid according to the present invention contains glycerin and propylene glycol.

The atomized liquid of the present invention also contains one or more of water, ethanol, essence, natural flavor, cooling agent, sweetener, preservative, fruit, and grain.

The present invention also provides an atomizer equipped with the atomizing liquid of the present invention, including an atomizing system, a power supply system and a control system.

The essence of the present invention is selected from, for example, fruit flavors, nut flavors, mint flavors, boozy flavors and other flavors. For fruit-flavored ingredients, such as apple-flavored ones, esters mainly include isopentyl isovalerate, ethyl isovalerate, geranyl formate, ethyl acetoacetate, phenylethyl isovalerate, amyl formate, butyric acid Isoamyl ester, ethyl acetate, isoamyl formate, allyl caproate, etc.; aldehydes mainly include benzaldehyde, citral, nonadecanal, etc.; alcohols mainly include phenylethyl alcohol, benzyl alcohol, linalool, etc. Grape-flavored ingredients, such as esters, mainly include methyl anthranilate, N-methyl anthranilate, ethyl acetate, methyl acetate, ethyl butyrate, ethyl 2-butyrate, 3- Ethyl hydroxybutyrate, ethyl hexanoate, propyl butyrate, ethyl octanoate, etc.; alcohols mainly include cis-3-hexen-1-ol, 1-hexanol, 1-hepten-3-ol, 3,4-Dimethyl-1-pentanol, 1-octanol, linalool, geraniol, 6-methyl-1-heptanol, etc.; aldehydes mainly include hexanal and trans-2-hexenal , benzaldehyde, 9-octadecenal, vanillin, peach aldehyde, etc.; carboxylic acids mainly include tartaric acid, citric acid, isobutyric acid, caproic acid, heptanoic acid, caprylic acid, etc. Sweet orange flavor ingredients, such as terpene Alkenes mainly include myrcene, α-pinene, valencia tangerene, α-myrcene, etc.; esters mainly include ethyl acetate, ethyl propionate, methyl butyrate, ethyl butyrate, 2-methyl methyl butyrate, ethyl 3-hydroxyhexanoate, etc.; aldehydes mainly include (E)-2-pentenal, octanal, nonanal, decanal, citral, orange aldehyde, etc.; alcohols mainly include Ethanol, (E)-2-hexen-1-ol, (Z)-3-hexen-1-ol, linalool and the like. Nut flavor ingredients, such as heterocyclics mainly include 2-acetylpyrrole, N-methyl-2-acetylpyrrole, pyridine, 4-methyl-5-hydroxyethylthiazole, 2,4-dimethyl -5-acetylthiazole, 2-methylpyrazine, 2,3-dimethylpyrazine, 2,5-dimethyldimethylpyrazine, 2,6-dimethylpyrazine, 2,5 -Dimethyl-4-hydroxy-3(2H)-furanone, 2-acetylfuran, etc.; esters mainly include ethyl formate, methyl acetate, ethyl acetate, isoamyl acetate, furfuryl acetate, propane Furfuryl acid, propyl heptanoate, ethyl nonanoate, benzyl benzoate, etc.; alcohols mainly include furfuryl alcohol, tetrahydrofurfuryl alcohol, linalool, etc.; aldehydes mainly include 2-methylbutyraldehyde, p-methylbenzene Formaldehyde, furfural, 5-methylfurfural, citral, etc.; ketones mainly include methylcyclopentenolone, 2,3-butanedione, 2,3-pentanedione, etc. Mint flavor ingredients such as menthol, menthone and menthyl acetate. Other ingredients include α-pinene, myrcene, α-terpinene, α-terpineol, β-terpineol, γ-terpinene, β-caryophyllene, α-fennelene, β-water Apirene, Pulegone, Isomenthone, Leafyl Acetate, Octyl Acetate, 3-Octyl Acetate, Menthyl Acetate, Isomenthyl Acetate, Neomenthyl Acetate, Terpinyl Acetate, Dihydroparsley Acetate ester, ethyl propionate, isopentyl isovalerate, phyllyl isovalerate, methyl benzoate, etc. Boozy ingredients, such as whiskey flavors, are isobutanol, isoamyl alcohol, beta-phenylethanol, acetaldehyde, acetal, isovaleraldehyde, furfural, acetic acid, caproic acid, octanoic acid, ethyl acetate, isobutyl acetate Esters, Isoamyl Acetate, Phenylethyl Acetate, Ethyl Propionate, Decyl Propionate, Isobutyl Isobutyrate, Ethyl Valerate, Isoamyl Isovalerate, Ethyl Hexanoate, Isoamyl Hexanoate Ethyl Caprylate, Isoamyl Caprylate, Ethyl Nonanoate, Ethyl Caprate, Ethyl Laurate, Ethyl Myristate, Ethyl Lactate, Vanillin, Ethyl Vanillin, etc. Rum flavor components such as rum ether, acetic acid, butyric acid, isovaleric acid, caproic acid, caprylic acid, ethyl formate, isobutyl formate, amyl formate, ethyl acetate, isobutyl acetate, isopentyl acetate ester, phenylethyl acetate, ethyl propionate, isobutyl butyrate, amyl butyrate, ethyl caproate, isopentyl caproate, ethyl heptanoate, ethyl caprylate, isopentyl caprylate, nonanoic acid ethyl ester, ethyl caprate, ethyl laurate, ethyl dodecanoate, ethyl myristate, ethyl palmitate, methyl benzoate, benzyl benzoate, guaiacol, benzaldehyde, fragrance Lanlin, ethyl vanillin, piperonal, etc. Other flavor ingredients such as cola taste, the composition is caffeine, frankincense oil, α-terpineol, vanillin, ethyl vanillin, piperonal, bornyl acetate, etc.

The natural fragrance of the present invention is selected from, for example, 0-5 parts of lemon oil, 0-5 parts of ginger oil, and 0-5 parts of rose oil. More natural fragrances such as clove bud oil, lavender oil, Sri Lanka bay leaf oil, Tolu concrete, Fenugreek concrete, Tree moss conctete, incense Viburnum bean extract (Vanilla extract), etc.

The preservative of the present invention preferably has 0-5 parts of preservative. Preservatives such as potassium sorbate, dehydroacetic acid and its sodium salt, methylparaben, ethylparaben, propylparaben, butylparaben, sodium diacetate, calcium propionate , Sodium Lactate.

The fruit and grain of the present invention, wherein the fruit is selected from one or more of white peach, grapefruit, lychee and lemon. The grain is selected from one or more of mung bean, red bean and barley. The form of the fruit in the composition includes fruit extract, freeze-dried fruit. The form of the cereal in the composition includes the extract of the cereal, the freeze-dried product of the cereal.

The cooling agent of the present invention is selected from menthol, menthone and menthyl acetate.

The composition of the present invention can be used as a component in the atomized liquid. When preparing the atomized liquid, the composition of the present invention can be added to any atomized liquid, including solid and liquid.

The atomization method of the atomized liquid of the present invention may be ultrasonic atomization, gas compression atomization, heating atomization and the like.

An atomized liquid of the present invention can be made of 1-25 parts of tea extract, 1-10 parts of mogroside, 0-5 parts of peppermint oil, extracts of fruits such as white peach, lemon, grapefruit, litchi, etc. , Freeze-dried products, mung bean, red bean, barley and other grain extracts, one or several parts of freeze-dried products 0-5 parts, lemon oil 0-5 parts, ginger oil 0-5 parts, rose, rose oil 0-5 parts 5 parts, essence 0-50 parts, cooling agent 0-25 parts, sweetener 0-15 parts, potassium sorbate 0-5 parts, edible ethanol 0-15 parts, water 0-25 parts, propylene glycol 0-100 parts Parts, 0-50 parts of glycerin, wherein the tea extract and mogroside are prepared into solid powder or liquid as a prescription and applied to the atomization device.

Glossary

bv is multiple volume, volume/weight ratio, and the unit is ml/g, L/kg, etc.

Mogroside CAS is 88901-36-4

The beneficial effects of the present invention are:

The composition of the present invention can be ingested in the form of atomization, and directly absorbed into the blood circulation system through the oral mucosa, which will significantly increase the bioavailability of small molecule polyphenols in the atomized liquid, and reduce the Health risks, increased safety.

The combination of the present invention can atomize tea extract, caffeine and other substances to help the human body to absorb, and can achieve rapid effect and stable quality. The preparation method has simple process and low cost.

Beneficial effect of the present invention is illustrated by experiment below

1. Sample preparation:

Each group is prepared in the following way by parts by weight:

1. Solvent: Weigh 3 parts of propylene glycol and 1 part of glycerin and mix them evenly.

2. Puer tea extract + solvent: Weigh 1.7 parts of Puer tea extract, add 98.3 parts of the above solvent, and mix well to obtain a Puer tea extract solution.

3. Luo Han Guo extract + solvent: Weigh 1.2 parts of Luo Han Guo extract, add 98.8 parts of the above solvent, and mix well.

4. Mogroside + solvent: Weigh 1.2 parts of mogroside, add 98.8 parts of the above-mentioned solvent, and mix to obtain the mogroside solution.

5. Pu-erh tea extract + mogroside + solvent: weigh 1 part of the above-mentioned Pu-erh tea extract solution, add 1 part of the above-mentioned mogroside solution, and mix well.

2. Experimental method

1 Antibacterial test:

1.1 Experimental strains

Candida albicans, Staphylococcus aureus, and Escherichia coli were purchased from China National Institutes for Food and Drug Control.

Bacterial liquid preparation: take the fresh culture (24h) from the slant surface of the nutrient agar medium of the 3rd to 14th generation of the strain, wash the bacterial lawn with 5ml0.03mol/L phosphate buffer saline (hereinafter referred to as PBS), and make the bacterial suspension uniform before use The above PBS was diluted to the desired concentration. (The required concentration is: drop 100 μL on the control sample, and the number of recovered bacteria is 1×10 ⁴ ~9×10 ⁴ cfu/piece)

1.2 Medium

Nutrient agar: peptone 10g, beef powder 3g, sodium chloride 5g, agar 15g, pH value: 7.2～7.4. Weigh 33g of this product, heat and dissolve it in 1000ml distilled water, pack into Erlenmeyer flasks, autoclave at 121°C for 15 minutes, and set aside.

1.3 Product antibacterial performance test

Take 4 tubes of each sample solution (5mL).

Take the above bacterial suspension, add 100 μL dropwise to each sample solution and control sample solution respectively, mix, start timing, and act for 10 minutes, use sterile tweezers to drop the sample solution (0.5mL) into test tubes containing 5mL PBS respectively , mix well, make appropriate dilution, then take 2-3 dilutions, draw 0.5mL respectively, put them in two plates, pour 15mL of nutrient agar medium cooled to 40-45°C, and rotate the plates to make them After the agar is solidified, turn the plate over and incubate at 35°C±2°C for 48 hours, count the viable colonies, and calculate the inhibition rate.

Determination of antibacterial effect: antibacterial rate ≥ 50% ~ 90%, the product has antibacterial effect, antibacterial rate ≥ 90%, the product has strong antibacterial effect.

2 Determination of 2,3-butanedione in release

2.1 Preparation of 2,3-butanedione standard stock solution

Weigh an appropriate amount of 2,3-butanedione into a 10mL brown volumetric flask, dissolve with ethanol to a constant volume, and the concentration is 10.0mg/mL. Store away from light at -18°C. Weigh an appropriate amount of standard stock solution into a brown volumetric flask, dilute to volume with ethanol, and prepare at least 5 standard working solutions. The standard working solutions are prepared and used immediately.

2.2 Suction

Insert the atomizing electronic cigarette device into the holder, carry out electronic cigarette suction according to the standard suction conditions, reset the counter of the number of suction ports and start counting, suck 100 ports of gas into the trap, and prepare a blank by the same preparation method solution.

2.3 Sample analysis

After the suction is completed, remove the first trap from the smoking machine, mix well, take an appropriate amount, filter it with a 0.45 μm PTFE filter membrane, and then use gas chromatography-mass chromatography for determination. The second trap is treated in the same way. A sample blank assay was performed without adding the sample.

3. Determination of carbonyl compounds in the release

3.1 Derivatization reagents

Weigh about 5g of 2,4-dinitrophenylhydrazine (DNPH) and add it to 500ml of acetonitrile, stir until completely dissolved, add 40mL of 10% perchloric acid and stir, add 500mL of water, stir well, and store at room temperature in the dark. Precisely pipette an appropriate amount of 8 carbonyl compound-DNPH mixed standard solutions, dilute with acetonitrile, and constant volume to prepare a mixed standard working solution containing 8 carbonyl compounds-DNPH, and store in the dark at -4°C.

3.2 Suction

Insert the atomizing electronic cigarette device into the holder, carry out electronic cigarette suction according to the standard suction conditions, reset the counter of the number of suction ports and start counting, suck 100 ports of gas into the trap, and prepare a blank by the same preparation method solution.

3.3 Sample Analysis

After the suction is completed, remove the first trap from the smoking machine, mix well, take an appropriate amount, filter it with a 0.45 μm PTFE filter membrane, and then use high performance liquid chromatography for determination. The second trap is treated in the same way. A sample blank assay was performed without adding the sample.

4. Taste test:

4.1 Screening of testers: recruit 20 adult testers, regardless of gender.

4.2 Inhalation method: The duration of smoke inhalation is 2-3 seconds, and the interval between each inhalation is 15 seconds.

4.3 Score range: 0-10 points. Each indicator is scored from 0 to 10.

4.4 Evaluation indicators and description:

Amount of smoke: the amount of smoke produced per puff when inhaled, relatively high "9-10 points", medium "7-8 points", and rarely "0-2 points".

Irritation: refers to the stimulation of the tip of the tongue and the mouth when the atomized smoke enters the mouth, which is divided into two types: hot and sour. No obvious irritation on the tip of the tongue and oral cavity is rated as "8-10 points". The tongue tip and oral cavity feel obvious irritation as "0-2 points".

Throat hit: refers to the irritation to the throat caused by the effective substances contained in the mouth when the atomized smoke is inhaled. In the acceptable range, the strong throat hit is "8-10". The throat hit is weak and the smoke is soft, which is "0-2 points".

Miscellaneous gas: Other odors in the atomized smoke except the characteristic aroma are collectively referred to as miscellaneous gas. "8-10 points" for no obvious miscellaneous gas, "0-2 points" for obvious miscellaneous gas.

Aftertaste: the remaining fragrance in the mouth when the atomized smoke is exhaled, and the degree of oral comfort. When there is no other bad breath in the mouth and it is comfortable, it is "8-10 points". There is residue in the mouth and the feeling of discomfort in the mouth is "0-2 points".

Fluid sensation: refers to the secretion of saliva from the mouth, including the cheeks, tongue surface, and tongue bottom. "8-10 points" for obvious fluid production in the mouth; "0-2 points" for strong dryness in the mouth.

Burnt smell: When inhaling continuously, it may cause the burnt smell produced by the atomizing core because it cannot be atomized in time, which will affect the aroma. When inhaled, there is no sticky smell and no change in aroma characteristics, giving "8-10 points". The paste smell is obvious, and the aroma is masked as "0-2 points".

Harmony: refers to the fusion and consistency of the aroma of the atomized e-liquid and the aroma of the functional substances of the herbal medicine. When inhaling, the aroma characteristics are obviously prominent, giving "8-10 points", and the aroma and herbal smell are clearly separated, "0-2 points".

Fragrance: You can feel the fragrance of herbal medicine after inhalation. Moderate aroma is "8-10 points", strong aroma is "6-7 points", and slight aroma is "0-2 points".

Sweetness: Sweetness can be felt during the pumping process. The sweetness is obviously "6-7 points", the sweetness is very light "4-5 points", and the sweetness is moderate "8-10 points".

3. Detection indicators:

1 Antibacterial test:

Test the antibacterial rate of the sample against Candida albicans, Staphylococcus aureus and Escherichia coli for 10 minutes.

2 Determination of harmful components in the release:

Detect the content of 2,3-butanedione, formaldehyde, acetaldehyde, acetone, acrolein, propionaldehyde, crotonaldehyde, 2-butanone and butyraldehyde in the sample release.

3 Taste score

4. Experimental results

1. Antibacterial test:

serial number name Candida albicans Staphylococcus aureus Escherichia coli 1 solvent 96.10% 96.30% 96.20% 2 Luo Han Guo Extract + Solvent 96.50% 96.30% 96.20% 3 Mogroside + solvent 96.60% 96.50% 96.30% 4 Pu'er Tea Extract + Solvent 97.30% 97.20% 97.50% 5 Pu'er Tea Extract + Mogroside + Solvent >99.9% >99.9% >99.9%

2 Determination of harmful components in the release:

Note: ND means not detected

3 Taste evaluation results

See the table below for the evaluation scores of each indicator.

5. Experimental conclusion:

1 Antibacterial test:

According to the evaluation criteria in Appendix C of GB15979-2002, the above results show that the solvent has a strong antibacterial rate, and the antibacterial rate of mogroside, Luo Han Guo extract, and Pu'er tea extract is slightly higher than that of the solvent after being combined with the solvent. , the antibacterial effect of mogroside is slightly better than that of Luo Han Guo extract, and the antibacterial effect of Pu'er tea extract is better than that of Mogroside and Luo Han Guo extract; the combination of Pu'er tea extract, mogroside and solvent has the highest antibacterial rate.

2 Detection of harmful components in the release:

The harmful components released by the solvent are in the middle, and the harmful components released by the mogroside are slightly less than that of the Luo Han Guo extract, but more than the solvent; the harmful components released by the Pu’er tea extract are significantly less than the mogroside, and slightly more than the solvent; After the compound and mogroside are combined, the release of harmful components is the least, which is significantly lower than that of the solvent.

3. Taste test:

10 indicators of the product are tested, and the sample of the invention has suitable aroma, mild sweetness, rich and delicate taste, strong body fluid feeling, pure and comfortable aftertaste, and basically no residue in the mouth and throat. Luo Han Guo extract + solvent, mogroside + solvent lacks the aroma of tea, Puer tea extract + solvent lacks the sweet taste, and the sense of body fluid is poor.

Detailed ways:

The present invention is further illustrated by the following examples, but not as a limitation of the present invention.

Example 1

The atomized liquid of the present invention can be obtained by dissolving and mixing according to the following formula:

Element Mass percentage (%) Pu-erh tea extract 1 Mogroside 0.5 peppermint 1.44 Eucalyptus oil 0.05 Menthol 0.01 ethanol 1 glycerin 58 Glycerol 38 total 100

Example 2

The atomized liquid of the present invention can be obtained by dissolving and mixing according to the following formula:

Element Mass percentage (%) Pu-erh tea extract 1 Mogroside 0.5 coffee tincture 0.2 2,3-Diethylpyrazine 0.02 2-Acetylpyrazine 0.002 Guaiacol 0.4 Vanillin 0.002 Propylene Glycol 37.876 glycerin 60 total 100

Example 3

The atomized liquid of the present invention can be obtained by dissolving and mixing according to the following formula:

Element Mass percentage (%) Pu-erh tea extract 0.2 Mogroside 0.3 cocoa tincture 1 Isoamyl alcohol 0.02 Isovaleraldehyde 0.002 Isovaleric acid 0.002 5-Methylfurfural 0.02 Guaiacol 0.02 Trimethylpyrazine 0.02 Propylene Glycol 37.876 glycerin 60.54 total 100

Example 4

The atomized liquid of the present invention can be obtained by dissolving and mixing according to the following formula:

Element Mass percentage (%) Pu-erh tea extract 0.5 Mogroside 0.3 lemon oil 0.02 sweet orange oil 0.05 nutmeg oil 0.02 neroli oil 0.05 ginger oil 0.005 Bornyl acetate 0.01 Ethyl vanillin 0.02 piperonal 0.02 Propylene Glycol 39.005 glycerin 60 total 100

Example 5

The atomized liquid of the present invention can be obtained by dissolving and mixing according to the following formula:

Element Mass percentage (%) Pu-erh tea extract 0.5 Mogroside 0.3 rose oil 0.1 sweet orange oil 0.05 nutmeg oil 0.02 ethyl acetate 0.05 Clover oil 0.005 Bornyl acetate 0.01 Vanillin 0.02 maltol 0.05 Propylene Glycol 38.895 glycerin 60 total 100

Example 6

The atomized liquid of the present invention can be obtained by dissolving and mixing according to the following formula:

Element Mass percentage (%) green tea extract 0.5 Mogroside 0.3 rose oil 0.1 sweet orange oil 0.05 nutmeg oil 0.02 ethyl acetate 0.05 Clover oil 0.005 Bornyl acetate 0.01 Vanillin 0.02 Maltol 0.05 Propylene Glycol 38.895 glycerin 60 total 100

Example 7

Production process of Pu'er tea extract:

In the first step, Pu’er tea leaves are decocted and extracted 3 times (0.5h, 0.5h, 0.5h; 10bv, 8bv, 8bv) using propylene glycol plus 95% ethanol (ethanol accounts for 1%, volume ratio) as the extraction solvent, and the extraction process is 80- Keep warm at 90°C, stir at a speed of 300r/min, filter the extract with 300 mesh, and set aside.

The second step: add water to the filter residue obtained in the previous step and concentrate under reduced pressure (≤70°C) for extraction until tea leaves (weight): concentrate (volume) = 1:2-1:3. After filtering the tea dregs, add 95% ethanol to the obtained concentrated solution until the concentration of ethanol is 80% for alcohol precipitation, let stand for 8 hours after cooling, and take the supernatant. The extract obtained in the first step is mixed with the supernatant in the second step, then concentrated and dried to obtain the extract powder.

Example 8

Production process of Pu'er tea extract:

In the first step, Pu’er tea leaves are decocted and extracted 3 times (0.5h, 0.5h, 0.5h; 10bv, 8bv, 8bv) using propylene glycol plus water (1% water, volume ratio) as the extraction solvent, and the extraction process is kept at 80-90°C , the stirring speed is 300r/min, the extract is filtered through 300 mesh, and set aside.

The second step: add water to the filter residue obtained in the previous step and concentrate under reduced pressure (≤70°C) for extraction until tea leaves (weight): concentrate (volume) = 1:2-1:3. After filtering the tea dregs, add 95% ethanol to the obtained concentrated solution until the concentration of ethanol is 80% for alcohol precipitation, let stand for 8 hours after cooling, and take the supernatant. The extract obtained in the first step is mixed with the supernatant in the second step, then concentrated and dried to obtain the extract powder.

Example 9

Production process of Pu'er tea extract:

In the first step, Pu’er tea leaves are decocted and extracted 3 times (0.5h, 0.5h, 0.5h; 10bv, 8bv, 8bv) using propylene glycol plus 95% ethanol (ethanol accounts for 20%, volume ratio) as the extraction solvent, and the extraction process is 80- Keep warm at 90°C, stir at a speed of 300r/min, filter the extract with 300 mesh, and set aside.

The second step: add water to the filter residue obtained in the previous step and concentrate under reduced pressure (≤70°C) for extraction until tea leaves (weight): concentrate (volume) = 1:2-1:3. After filtering the tea dregs, add 95% ethanol to the obtained concentrated solution until the concentration of ethanol is 80% for alcohol precipitation, let it stand for 12 hours after cooling, and take the supernatant. The extract obtained in the first step is mixed with the supernatant in the second step, then concentrated and dried to obtain the extract powder.

Example 10

Production process of Pu'er tea extract:

In the first step, Pu’er tea leaves are decocted and extracted 3 times (0.5h, 0.5h, 0.5h; 10bv, 8bv, 8bv) using propylene glycol plus water (water accounts for 10%, volume ratio) as the extraction solvent, and the extraction process is kept at 80-90°C , the stirring speed is 300r/min, the extract is filtered through 300 mesh, and set aside.

The second step: add water to the filter residue obtained in the previous step and concentrate under reduced pressure (≤70°C) for extraction until tea leaves (weight): concentrate (volume) = 1:2-1:3. After filtering the tea dregs, add 95% ethanol to the obtained concentrated solution until the concentration of ethanol is 80% for alcohol precipitation, let it stand for 12 hours after cooling, and take the supernatant. The extract obtained in the first step is mixed with the supernatant in the second step, then concentrated and dried to obtain the extract powder.

Example 11

Green tea extract production process:

In the first step, the green tea leaves are decocted and extracted 3 times (0.5h, 0.5h, 0.5h; 10bv, 8bv, 8bv) with propylene glycol and water (water accounts for 1%, volume ratio) as the extraction solvent, and the extraction process is kept at 80-90°C , the stirring speed is 300r/min, the extract is filtered through 300 mesh, and set aside.

The second step: add water to concentrate the filter residue obtained in the previous step under reduced pressure (≤70°C) to tea leaves (weight): concentrate (volume) = 1:2-1:3. After filtering the tea dregs, add 95% ethanol to the obtained concentrated solution until the concentration of ethanol is 80% for alcohol precipitation, let it stand for 12 hours after cooling, and take the supernatant. The extract obtained in the first step is mixed with the supernatant in the second step, then concentrated and dried to obtain the extract powder.

Example 12

Weigh 30g of glycerin and 60g of propylene glycol and mix, add 5g of the Pu-erh tea extract obtained in Example 7, keep stirring evenly at 60°C, add 5g of mogroside, stir, and let the temperature drop to room temperature to obtain the atomized liquid .

Example 13

Weigh 30g of glycerol and 60g of propylene glycol and mix them, add 1g of the Pu’er tea extract obtained in Example 7, keep stirring evenly at 60°C, add 10g of mogroside, stir, and let the temperature drop to room temperature to obtain the atomized liquid .

Example 14

Weigh 30g of glycerin and 200g of propylene glycol and mix, add 25g of the Pu-erh tea extract obtained in Example 7, keep stirring evenly at 60°C, add 1g of mogroside, stir, and let the temperature drop to room temperature to obtain the atomized liquid .

Example 15

Weigh 30g of glycerol and 200g of propylene glycol and mix, add 25g of the Pu-erh tea extract obtained in Example 7, keep stirring evenly at 60°C, add 10g of mogroside, stir, and let the temperature drop to room temperature to obtain the atomized liquid .

Example 16

Weigh 3g of glycerin and 60g of propylene glycol and mix, add 5g of the Pu-erh tea extract obtained in Example 7, keep stirring evenly at 60°C, add 2g of mogroside, stir, and let the temperature drop to room temperature to obtain the atomized liquid .

Example 17

Weigh 55g of glycerol and 60g of propylene glycol and mix, add 5g of the Pu-erh tea extract obtained in Example 7, keep stirring evenly at 60°C, add 8g of mogroside, stir, and let the temperature drop to room temperature to obtain the atomized liquid .

Example 18

Weigh 130g of glycerin and 60g of propylene glycol and mix, add 20g of the Pu-erh tea extract obtained in Example 7, keep stirring evenly at 60°C, add 2g of mogroside, stir, and let the temperature drop to room temperature to obtain the atomized liquid .

Example 19

Weigh 125g of glycerol and 125g of propylene glycol and mix them, add 20g of the Pu’er tea extract obtained in Example 7, keep stirring evenly at 60°C, add 8g of mogroside, stir, and let the temperature drop to room temperature to obtain the atomized liquid .

Example 20

Weigh 3g of glycerin and 60g of propylene glycol and mix, add 5g of the Pu-erh tea extract obtained in Example 7, keep stirring evenly at 60°C, add 2g of mogroside, stir, and let the temperature drop to room temperature to obtain the atomized liquid .

Example 21

Weigh 50g of glycerol and 60g of propylene glycol and mix them, add 5g of the Pu-erh tea extract obtained in Example 7, keep stirring evenly at 60°C, add 8g of mogroside, stir, and let the temperature drop to room temperature to obtain the atomized liquid .

Example 22

Weigh 130g of glycerin and 60g of propylene glycol and mix, add 20g of the Pu-erh tea extract obtained in Example 7, keep stirring evenly at 60°C, add 2g of mogroside, stir, and let the temperature drop to room temperature to obtain the atomized liquid .

Example 23

Weigh 190g of glycerol and 60g of propylene glycol and mix, add 20g of the Pu-erh tea extract obtained in Example 7, keep stirring evenly at 60°C, add 8g of mogroside, stir, and let the temperature drop to room temperature to obtain the atomized liquid .

Example 24

Weigh 30g of glycerin and 60g of propylene glycol and mix, add 8g of the Pu-erh tea extract obtained in Example 7, keep stirring evenly at 60°C, add 3g of mogroside, stir, and let the temperature drop to room temperature to obtain the atomized liquid .

Example 25

Weigh 60g of glycerin and 60g of propylene glycol and mix, add 8g of the Pu-erh tea extract obtained in Example 8, keep stirring evenly at 50°C, add 6g of mogroside, stir, and let the temperature drop to room temperature to obtain the atomized liquid .

Example 26

Weigh 100g of glycerol and 60g of propylene glycol and mix, add 15g of the Pu-erh tea extract obtained in Example 9, keep stirring evenly at 50°C, add 3g of mogroside, stir, and let the temperature drop to room temperature to obtain the atomized liquid .

Example 27

Weigh 120g of glycerol and 60g of propylene glycol and mix, add 15g of the Pu-erh tea extract obtained in Example 10, keep stirring evenly at 50°C, add 6g of mogroside, stir, and let the temperature drop to room temperature to obtain the atomized liquid .

Example 28

Weigh 100g of glycerol and 60g of propylene glycol and mix them, add 15g of the green tea extract obtained in Example 11, keep stirring evenly at 50°C, add 3g of mogroside, stir, and lower the temperature to room temperature to obtain an atomized liquid.

Example 29

After weighing 60g of glycerin and 60g of propylene glycol and mixing, add 10g of the green tea extract obtained in Example 11, keep stirring evenly at 50°C, add 4g of mogroside, stir, and lower the temperature to room temperature to obtain an atomized liquid.

Example 30

Weigh 100g of glycerol and 58g of propylene glycol and mix, add 12g of the green tea extract obtained in Example 11, keep stirring at 50°C, add 6g of mogroside, stir, and lower the temperature to room temperature to obtain an atomized liquid.

Claims (10)

1. An aerosolized composition comprising tea extract and mogroside.

2. The composition of claim 1, wherein the weight ratio of tea extract to mogroside is from 1 to 25:1-10.

3. The composition of claim 1, wherein the weight ratio of tea extract to mogroside is from 5 to 20:2-8.

4. The composition of claim 1, wherein the weight ratio of tea extract to mogroside is from 8-15:3-6, preferably 10-12:4-6.

5. The composition of claim 1, wherein the Pu ' er tea extract is a Pu ' er tea extract, the Pu ' er tea extract is obtained by extracting Pu ' er tea with a solvent containing ethanol, the extraction comprises two steps, the first step is extraction with the solvent, a solvent extracting solution is obtained by filtration, the second step is alcohol precipitation is carried out on filtered filter residue with ethanol after adding water, an alcohol precipitation solution is obtained, and the solvent extracting solution and the alcohol precipitation solution are combined to obtain the Pu ' er tea extract.

6. An atomized liquid characterized by containing the composition according to any one of claims 1 to 5.

7. The atomized liquid of claim 6, wherein the composition is present in the atomized liquid in a weight ratio of: 1:1000 to 130:1000.

8. the atomized liquid of claim 6, wherein the atomized liquid contains one or a combination of glycerol and propylene glycol.

9. The atomized liquid of claim 6, wherein the atomized liquid further comprises one or more of water, ethanol, essence, natural flavors, cooling agents, sweeteners, preservatives, fruits, and grains.

10. A nebulizer containing a composition or nebulised liquid according to any one of claims 1 to 9, comprising a nebulization system, a power supply system and a control system.