CN115336745A - Composition and application thereof - Google Patents

Abstract

The invention discloses a composition and its application, and relates to the technical field of compositions. The invention provides a composition, comprising the following components in parts by weight: 1.5-6 parts of comprehensive fruit and vegetable enzyme liquid, 0.05-0.3 parts of Yerba Mate extract, 0.05-0.2 parts of ginseng peptide, 0.05-0.2 parts of wolfberry, and 0.03 parts of Polygonatum ‑0.2 part, spearmint extract 0.01‑0.1 part, turmeric 0.01‑0.07 part. The present invention uses specific ingredients, Yerba mate extract, ginseng peptide, wolfberry, Polygonatum, spearmint extract and turmeric, through synergistic synergy of various anti-fatigue functional raw materials, multi-channel anti-fatigue, effectively improving concentration and memory, synergistic Improve brain health. The invention makes the product have good anti-fatigue, brain-building and memory-improving effects through reasonable proportioning.

Description

A kind of composition and its application

technical field

The invention relates to the technical field of compositions, in particular to a composition and its application.

Background technique

Fatigue refers to the inability of the physiological process to continue its function at a specific level and/or to maintain a predetermined exercise intensity, including peripheral fatigue and central fatigue. Currently, the core raw materials used in anti-fatigue products on the market are taurine, B vitamins and caffeine, supplemented by the addition of ginseng and other Chinese herbal medicine components, and the homogeneity of ingredients is serious. Raw materials taurine and B vitamins are more effective for sports people, can relieve fatigue caused by high-intensity body exercise, promote body energy metabolism, and then improve exercise capacity, but have limited effect on groups prone to central fatigue. Raw caffeine can delay fatigue by regulating the central nervous system without affecting energy metabolism, but long-term intake will produce tolerance and dependence, which is harmful to the human body.

There are huge groups of students and office workers in contemporary society, and there is a huge demand for relieving central fatigue and improving learning and concentration. However, there are anti-fatigue products or brain-invigorating and intellectual-improving products on the market at present, which cannot satisfy the needs of the public well.

Contents of the invention

Based on this, the object of the present invention is to provide a composition with anti-fatigue and memory-improving functions to overcome the shortcomings of the above-mentioned prior art. The present invention provides a composition capable of effectively improving concentration and memory, improving brain health and anti-fatigue through a specific ratio.

In order to achieve the above object, the technical solution adopted by the present invention is: a composition comprising the following components in parts by weight: 1.5-6 parts of comprehensive fruit and vegetable enzyme liquid, 0.05-0.3 parts of yerba mate extract, 0.05-0.2 parts of ginseng peptide 0.05-0.2 parts of wolfberry, 0.03-0.2 parts of sealwort, 0.01-0.1 parts of spearmint extract, 0.01-0.07 parts of turmeric.

The present invention uses specific ingredients, Yerba mate extract, ginseng peptide, wolfberry, sealwort, spearmint extract and turmeric, synergistically synergizes with various anti-fatigue functional raw materials, multi-channel anti-fatigue, effectively improves concentration and memory, and synergizes Improve brain health. The invention makes the product have the best effects of anti-fatigue, strengthening the brain and improving memory through reasonable proportioning.

Preferably, the composition includes the following components in parts by weight: 2-4 parts of comprehensive fruit and vegetable enzyme liquid, 0.1-0.2 parts of Yerba Mate extract, 0.08-0.15 parts of ginseng peptide, 0.08-0.15 parts of wolfberry, and 0.05 parts of Polygonatum -0.1 part, spearmint extract 0.02-0.06 part, turmeric 0.02-0.05 part.

After a lot of experiments, the inventor found that the combination of fruit and vegetable enzyme liquid, Yerba mate extract, ginseng peptide, wolfberry, sealwort, spearmint extract, and turmeric synergistically achieved good anti-fatigue, brain-building, and memory-improving effects. Effect. When the weight of each component of the comprehensive fruit and vegetable enzyme liquid, yerba mate extract, ginseng peptide, wolfberry, sealwort, spearmint extract, and turmeric changes, it will directly affect the effects of anti-fatigue, brain strengthening, and memory improvement. The influence of the gradual increase or decrease of the content of a single component on the effect of the composition is not linear, and when the above-mentioned parts by weight are selected, the effect of the composition against fatigue, strengthening the brain and improving memory is better.

Further preferably, the composition includes the following components in parts by weight: 3 parts of comprehensive fruit and vegetable enzyme liquid, 0.12 parts of Yerba Mate extract, 0.1 part of ginseng peptide, 0.1 part of wolfberry, 0.08 part of Polygonatum, and spearmint extract 0.04 parts, turmeric 0.03 parts.

After a lot of experiments, the inventor found that the combination of fruit and vegetable enzyme liquid, yerba yerba extract, ginseng peptide, wolfberry, sealwort, spearmint extract, and turmeric can resist fatigue, strengthen the brain, and improve memory. achieve the best.

In addition, the present invention provides the application of the above composition in food or medicine.

Further, the present invention provides a liquid preparation, the liquid preparation includes the above composition, and the liquid preparation also includes auxiliary materials.

Preferably, the auxiliary materials include sweeteners, acidity regulators, flavoring agents, and solvents. The sweetener is at least one of erythritol and steviol glycoside, the acidity regulator is at least one of citric acid and sodium citrate, the flavoring agent is food essence, and the solvent is water .

Preferably, the liquid preparation, based on 100 parts by weight, includes the following components by weight: 1.5-6 parts of comprehensive fruit and vegetable enzyme liquid, 0.05-0.3 parts of Yerba mate extract, 0.05-0.2 parts of ginseng peptide, 0.05-0.05 parts of wolfberry 0.2 parts, sealwort 0.03-0.2 parts, spearmint extract 0.01-0.1 parts, turmeric 0.01-0.07 parts, sweetener 2-12 parts, acidity regulator 0.05-0.6 parts, flavoring agent 0.05-0.2 parts, solvent quantity.

Preferably, the liquid preparation, based on 100 parts by weight, includes the following components by weight: 2-4 parts of comprehensive fruit and vegetable enzyme liquid, 0.1-0.2 parts of Yerba Mate extract, 0.08-0.15 parts of ginseng peptide, 0.08-0.08 parts of wolfberry 0.15 parts, sealwort 0.05-0.1 parts, spearmint extract 0.02-0.06 parts, turmeric 0.02-0.05 parts, sweetener 4-9 parts, acidity regulator 0.1-0.5 parts, flavoring agent 0.08-0.15 parts, solvent quantity.

Preferably, the sweetener is at least one of erythritol and steviol glycoside; the acidity regulator is at least one of citric acid and sodium citrate; the flavoring agent is food flavor; the The solvent is water.

In addition, the present invention provides the preparation method of the liquid preparation, comprising the following steps:

(1) Weigh each component by above-mentioned parts by weight;

(2) mix the yerba yerba extract, ginseng peptide, wolfberry, sealwort, spearmint extract, and turmeric evenly, add a solvent, stir and heat until completely dissolved, and obtain mixture A;

(3) Mix the sweetener and the acidity regulator evenly, add a solvent, stir and heat until transparent to obtain a mixture B;

(4) Stir and mix the mixture A obtained in the step (1), the mixture B obtained in the step (2), the comprehensive fruit and vegetable enzyme liquid, the flavoring agent, and the solvent, and homogeneously pack in a can to obtain the liquid preparation.

Preferably, in the step (2), the heating temperature is 50-60°C; in the step (3), the heating temperature is 50-60°C; in the step (4), the stirring speed is 15 -20r/min.

Compared with the prior art, the beneficial effects of the present invention are: the yerba mate extract provided by the present invention has the effects of refreshing and anti-fatigue, has no strong irritation to the body, does not damage the heart and brain, and does not affect sleep; comprehensive Fruit and vegetable enzyme liquid has multiple physiological functions, can promote body metabolism, blood circulation, and has significant anti-oxidation and alleviating body fatigue functions; this invention uses Yerba mate extract as the main anti-fatigue component, supplemented by adding ginseng peptide, wolfberry and sealwort, etc. Raw materials derived from traditional Chinese medicinal materials, a comprehensive fruit and vegetable enzyme solution containing multiple functions, as well as spearmint extract and turmeric, synergistically synergized through a variety of anti-fatigue raw materials, multi-channel anti-fatigue, effectively improve concentration and memory, and synergistically improve brain health. The invention makes the product have the best effects of anti-fatigue, strengthening the brain and improving memory through reasonable proportioning.

Detailed ways

In order to better illustrate the purpose, technical solutions and advantages of the present invention, the present invention will be further described below in conjunction with specific examples.

In the embodiments, the experimental methods used are conventional methods unless otherwise specified, and the materials and reagents used, etc., can be obtained from commercial sources if not otherwise specified; the specific sources of the raw materials used in the present invention are as follows: comprehensive fruit and vegetable enzyme The liquid was purchased from Hanchenshi Biotechnology (Liaoning) Group Co., Ltd., the extract of Yerba mate was purchased from Guangzhou Kanglai Food Additives Co., Ltd., the ginseng peptide was purchased from Shanghai Laique Biotechnology Co., Ltd., and the wolfberry was purchased from Cangzhou Enji Biological Products Co., Ltd. Company, Polygonatum was purchased from Huangshan Hualvyuan Biotechnology Co., Ltd., spearmint extract Neumentix was purchased from Jianming (China) Technology Co., Ltd., and turmeric was purchased from Henan Zhongda Hengyuan Biotechnology Co., Ltd.

Embodiment 1-6 and comparative example 1-10

The components and parts by weight of the liquid preparations described in Examples 1-6 and Comparative Examples 1-10 of the present invention are selected as shown in Table 1 and Table 2 below, the preparation of the liquid preparations described in Examples and 1-6 Comparative Examples 1-10 method, comprising the steps of:

(1) Weigh each component by above-mentioned parts by weight;

(2) Mix the yerba mate extract, ginseng peptide, wolfberry, sealwort, spearmint extract, and turmeric evenly, add a solvent, stir and heat until completely dissolved, and the heating temperature is 55°C to obtain a mixture A;

(3) Mix the sweetener and the acidity regulator evenly, add a solvent, stir and heat until transparent, and the heating temperature is 55° C. to obtain a mixture B;

(4) Stir and mix the mixture A obtained in step (1), the mixture B obtained in step (2), the comprehensive fruit and vegetable enzyme liquid, flavoring agent, and solvent, the stirring speed is 20r/min, and it is packed in a homogeneous can, The liquid formulation is obtained.

Table 1

Components (parts by weight) Example 1 Example 2 Example 3 Example 4 Example 5 Example 6 Comprehensive fruit and vegetable enzyme liquid 1.5 2.5 3 4 6 3 Yerba Mate Extract 0.05 0.1 0.12 0.15 0.3 0.12 Ginseng peptide 0.2 0.12 0.1 0.08 0.05 0.1 wolfberry 0.2 0.15 0.1 0.08 0.05 0.1 Polygonatum 0.2 0.1 0.08 0.05 0.03 0.08 Spearmint Extract 0.01 0.02 0.04 0.05 0.1 0.04 turmeric 0.07 0.02 0.03 0.05 0.01 0.03 Erythritol 2 6 7 8 10 6 steviol glycoside 0.002 0.005 0.01 0.015 0.02 0.005 citric acid 0.5 0.3 0.2 0.15 0.05 0.3 Sodium citrate 0.1 0.07 0.05 0.02 0.01 0.07 food flavor 0.05 0.08 0.1 0.13 0.2 0.08 water margin margin margin margin margin margin

Table 2

Performance Testing

Test Example 1 Anti-fatigue function test.

Testing process:

(1) Weight-bearing swimming test.

Choose mice with a body weight of 18-22g, half male and half male, and divide them into 17 groups, 10 in each group. The control group is given purified water at 0.2ml/10g mouse weight, and the groups of Examples 1-6 and Comparative Examples 1-10 are given 0.2ml/10g mouse body weight was administered to the corresponding test sample. Oral gavage for 28 days. After the last administration of the test substance (or purified water) for 30 minutes, put a lead wire of 5% of the mouse’s body weight on the base of the mouse’s tail, and put it into a swimming tank with a water temperature of 25.0±0.5°C and a water depth of 40cm. In the same period, the time from the start of swimming to exhaustion (the mouse could not surface 10s after sinking) was recorded with a stopwatch as the exhaustive swimming time of the mice.

(2) Biochemical indicators.

After the mice swam for 30 minutes, the eyeballs were picked to collect blood, which was placed in a centrifuge tube. Centrifuge at 5000r/min for 10min, separate serum, and measure serum urea value and whole blood lactic acid content by ultraviolet spectrophotometry.

Test results: as shown in Table 3.

table 3

It can be known from the above table that, compared with the control group, the time to exhaustion of the mice in each example group and the comparative example group was prolonged, and the difference was significant (P<0.01). Compared with the control group in each example group, the exhaustion time of the mice was longer, and the difference was significant (P<0.01). Among embodiments 1-5, the exhaustion time of embodiment 3 is the longest, showing that this embodiment is the optimal formula combination, and the effect of relieving fatigue is the best; the exhaustion time of embodiment 6 is close to embodiment 3, and this is because the two The content of functional raw materials is the same, and the resulting anti-fatigue effect is also similar; comparative examples 1-7 also have a greater degree of prolongation of the exhaustion time, indicating that the components: enzymes, yerba mate extract, ginseng peptide, wolfberry, Polygonatum, spearmint extract and turmeric have certain effects on relieving fatigue respectively.

Compared with the control group, the exhaustion time of the mice in Comparative Example 8 was prolonged, but significantly lower than that of the mice in Example 1-6 groups, and the difference was significant (P<0.01). This shows that, when the weight portion of the composition provided by the invention is not selected within a specific range, even if the components are the same, its anti-fatigue effect will be greatly reduced. Compared with Example 3, the exhaustion time of the mice in Comparative Example 9 is relatively short, and the difference is significant (P<0.01), which shows that the composition provided by the present invention is selected by the inventor through a large number of experiments, and there is mutual interaction. In order to achieve the synergistic effect, even if the same type of green tea extract with anti-fatigue effect is used to replace the yerba mate extract, the final effect will be significantly worse than the embodiment of the present invention.

The content of serum urea increases with the increase of the body's exercise load, and the worse the body's adaptability to the load, the more obvious the increase of serum urea. As shown in the table above, compared with the matched group, the serum urea of the embodiment group and the comparative example group all reduces to a certain extent (P＜0.01, significant difference is arranged), wherein the serum urea amount of embodiment 3 is the lowest, shows that its The effect is optimal; the serum urea content of embodiment 6 is close to that of embodiment 3, and this is due to the same effect raw material content of the two, and the resulting anti-fatigue effect is also similar; the serum urea content of comparative examples 1-7 is all significant decreased, indicating that the components: enzymes, Yerba Mate extract, ginseng peptide, wolfberry, sealwort, spearmint extract and turmeric have a certain effect on relieving fatigue. Compared with the control group, the serum urea content of mice in Comparative Example 8 decreased to a certain extent, but it was significantly lower than the reduction rate of serum urea content in mice of Example 1-6 groups, and the difference was significant (P<0.01). It shows that, when the weight part of the composition provided by the invention is not selected within a specific range, even if the components are the same, its anti-fatigue effect will be greatly reduced. Compared with Example 3, the degree of reduction of serum urea in mice of Comparative Example 9 is less, indicating that the composition provided by the present invention is selected by the inventor through a large number of experiments, and has produced a synergistic effect with each other. The same type of green tea extract with anti-fatigue effect is used to replace the Yerba yerba mate extract, and the final effect is obviously worse than that of the embodiment of the present invention.

As the exercise continues, the body will produce the metabolite lactic acid, and the accumulation of lactic acid will lead to fatigue. The faster the blood lactic acid clearance metabolism, the higher the aerobic metabolism capacity, which is more conducive to the rapid elimination of fatigue. As can be seen from the above table, compared with the control group, the blood lactic acid in the example group and the comparative example group has decreased to a certain extent (P<0.01 in the example group, P<0.05 in the comparative example group), and the blood lactic acid content in Example 3 is the lowest , showing that its anti-fatigue effect is optimal; the blood lactic acid scavenging effect of embodiment 6 is close to that of embodiment 3, and this is because the content of the functional raw materials of the two is the same, and the anti-fatigue effect produced thereby is also similar; the blood lactic acid of comparative example 8 Lactic acid has only reduced 6.0%, is obviously lower than embodiment 1-6 group mouse serum urea content reduction rate (P＜0.01, has significant difference), illustrates that the weight portion selection of composition provided by the present invention is not in specific range , even if the components are the same, its anti-fatigue effect will be greatly reduced. Compared with Example 3, the degree of reduction of blood lactic acid in the mice of Comparative Example 9 was less, and the difference was significant (P<0.01). The composition provided by the present invention was selected by the inventor through a large number of experiments, and there was a significant difference between them. In order to achieve the synergistic effect, even if the same type of green tea extract with anti-fatigue effect is used to replace the yerba mate extract, the final effect will be significantly worse than the embodiment of the present invention.

Test example 2 improves memory function test.

Test process: platform test; select mice weighing 18-22g, half male and half male, divided into 17 groups, 10 mice in each group, and the control group is given purified water at 0.2ml/10g mouse weight; embodiment 1-6 groups and Ratio 1-10 groups were given corresponding test samples at 0.2ml/10g mouse body weight. Samples were given for 30 consecutive days, and training began the day after the last sample was given. Put the animal into the reaction box to adapt to the environment for 3 minutes, then place the animal on the copper grid in the reaction box, and immediately pass through 36V alternating current. Animals received electric shocks and their normal response was to jump back to the platform to escape the noxious stimulus. Most animals may jump to the copper grid again or more times, and jump back to the platform quickly after receiving the electric shock. Put the animals on the platform in the reaction box, and record the number of mistakes each mouse jumped off the platform within 5 minutes and the escape latency of jumping off the platform for the first time, as an indicator of learning ability. After 24 hours, the formal test was carried out, the mice were placed on the platform, and the latency period of each mouse jumping off the platform for the first time and the number of electric shocks within 5 minutes were recorded.

Test results: as shown in Table 4.

Table 4

It can be seen from the above table that, compared with the control group, the escape latency of the mice in the example group and the control group is significantly longer (P<0.01). Among embodiments 1-5, the escape latency of embodiment 3 is the longest, showing that this embodiment is the optimal formula combination, and it has the best effect on improving memory; the escape latency of embodiment 6 is close to embodiment 3, and this is because both The content of functional raw materials is the same, and the resulting improvement effect on memory is also similar. Comparative examples 1-7 also prolong the escape latency to a greater extent, indicating that the components: enzymes, yerba mate extract, ginseng peptide, wolfberry, sealwort, spearmint extract and turmeric have certain effects on improving memory respectively. The escape latency period of Comparative Example 2, Comparative Example 6 and Comparative Example 7 is shorter than that of other comparative examples, indicating that Yerba Mate extract, spearmint extract and turmeric are more effective in improving memory. When no addition is made, the effect of improving memory will be significantly reduced. Compared with the matched group, the escape latency of Comparative Example 10 has a certain degree of prolongation, but it is obviously lower than the latency prolongation rate (P＜0.01, significant difference) of embodiment 1-6 group, illustrates thus, spearmint extract When the added amount of the drug is lower than a certain amount, its effect of improving memory will be greatly reduced. The results of the comparative examples show that the compositions provided by the present invention were selected by the inventors through a large number of experiments, and they have synergistic effects with each other.

As can be known from the above table, the embodiment group and the comparative example group are compared with the control group, and the mouse platform jumping test error number of times all reduces, and the embodiment group and the comparative example group are compared with the control group, and the difference is significant (P＜ 0.01). Among embodiments 1-5, the number of times of mistakes in embodiment 3 is the least and shows that this embodiment is the optimal formula combination, and the effect of invigorating the brain is the best; the average number of times of mistakes in embodiment 6 is close to embodiment 3, and this is due to the efficacy of both The content of raw materials is the same, and the resulting brain-invigorating effect is also similar. The number of errors in comparative examples 1-7 has a certain decrease, indicating that the components: enzymes, yerba yerba extract, ginseng peptide, wolfberry, sealwort, spearmint extract and turmeric have certain effects on improving memory respectively. Compared with the matched group, the number of mistakes in Comparative Example 10 has decreased, but it is significantly lower than the reduction rate of the number of mistakes in Example 1-6 groups (P＜0.01, there is a significant difference), thus illustrating that the spearmint extract When the added amount is lower than a certain amount, its memory-improving effect will be greatly reduced. The results of the comparative examples show that the compositions provided by the present invention were selected by the inventors through a large number of experiments, and they have synergistic effects with each other.

Test Example 3 Acute toxicity test (MTD method).

Test process: select mice weighing 18-22 g, half male and half male, and divided into 7 groups (blank control group, groups of Examples 1-6), 10 mice in each group. The use of experimental animals was carried out in accordance with the regulations for the use of experimental animals. The animal feeding ensured a 12h/12h light-dark cycle, the temperature was 23±1°C, the humidity was 50±10%, and there was free access to food and water. All the mice were fasted overnight for 16 h before the experiment, without restriction of drinking water. During the formal experiment, the amount of gavage each time was 0.8ml/gavage, and the test sample was given once every 6 hours in a day (the control group was given purified water), twice in total, and the test sample was given by oral gavage. After 3 days of administration, the observation was continued for 14 days.

Test results: No death or abnormal phenomenon occurred in the routine feeding of mice within 14 days after administration, thus proving that the preparations of Examples 1-6 have no toxic and side effects and can be used safely.

Test example 4 food trial test.

Test process: randomly select 50 volunteers aged 25-45, half male and half male. At 2-3 p.m., test samples were provided for questionnaire survey, and the drinking volume of the samples was 100ml per serving, and the samples were drunk continuously for 5 days. The taste test was conducted after drinking on the first day, and the anti-fatigue effect and memory improvement effect were investigated 1 hour after drinking on the fifth day. The same batch of volunteers needs to test competing products and samples of Examples 1-6, and different samples need to be tested after 2 days.

Test results: as shown in Table 5.

table 5

It can be seen from the above table that compared with the control group of competing products, the taste evaluation of the liquid preparations prepared in Examples 2-4 and Example 6 is better, and the liquid preparation of Example 3 has the highest score, and 80% of the volunteers think that Taste is better or very good; Embodiment 2, embodiment 4 and embodiment 6 have 72%, 70% and 72% volunteers to think taste is better or very good respectively, and this investigation shows that embodiment 2-4 and embodiment The taste acceptance of 6 is higher; embodiment 1 and embodiment 5 have 64% and 60% volunteers to think mouthfeel is good or very good respectively, close with competing products, but negative evaluation (poor or very poor) is relatively competitive The products are less.

In terms of anti-fatigue and improving memory sensory experience, the liquid preparations prepared in Examples 1-6 have better effects than competing products, and the somatosensory effects of Examples 3 and 6 are the best, both of which have 88% volunteers The volunteers think that their sense of fatigue and memory are improved, because the content of the two functional raw materials is the same, so they present a similar effect somatosensory; the scores of Examples 2 and 4 are also higher, and 82% and 84% of the volunteers think that Fatigue and memory are improved; 76% and 78% of the volunteers in Example 1 and Example 5 think that they have the effect of relieving fatigue and improving memory, which is better than competing products.

Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention rather than limit the protection scope of the present invention. Although the present invention has been described in detail with reference to the preferred embodiments, those of ordinary skill in the art should understand that The technical solution of the present invention can be modified or equivalently replaced without departing from the spirit and scope of the technical solution of the present invention.

Claims (10)

1. The composition is characterized by comprising the following components in parts by weight: 1.5-6 parts of comprehensive fruit and vegetable enzyme liquid, 0.05-0.3 part of yerba mate extract, 0.05-0.2 part of ginseng peptide, 0.05-0.2 part of medlar, 0.03-0.2 part of rhizoma polygonati, 0.01-0.1 part of spearmint extract and 0.01-0.07 part of turmeric.

2. The composition of claim 1, comprising the following components in parts by weight: 2-4 parts of comprehensive fruit and vegetable enzyme liquid, 0.1-0.2 part of yerba mate extract, 0.08-0.15 part of ginseng peptide, 0.08-0.15 part of medlar, 0.05-0.1 part of sealwort, 0.02-0.06 part of spearmint extract and 0.02-0.05 part of turmeric.

3. The composition of claim 2, comprising the following components in parts by weight: 3 parts of comprehensive fruit and vegetable enzyme liquid, 0.12 part of yerba mate extract, 0.1 part of ginseng peptide, 0.1 part of medlar, 0.08 part of rhizoma polygonati, 0.04 part of spearmint extract and 0.03 part of turmeric.

4. Use of a composition according to any one of claims 1 to 3 in a food or pharmaceutical product.

5. A liquid formulation comprising the composition of any one of claims 1-3, wherein the liquid formulation further comprises an excipient.

6. The liquid formulation of claim 5, wherein the excipients comprise sweeteners, acidity regulators, flavoring agents, solvents.

7. The liquid formulation according to claim 6, comprising the following components in parts by weight, based on 100 parts by weight: 1.5-6 parts of comprehensive fruit and vegetable enzyme liquid, 0.05-0.3 part of yerba mate extract, 0.05-0.2 part of ginseng peptide, 0.05-0.2 part of medlar, 0.03-0.2 part of sealwort, 0.01-0.1 part of spearmint extract, 0.01-0.07 part of turmeric, 2-12 parts of sweetening agent, 0.05-0.6 part of acidity regulator, 0.05-0.2 part of flavoring agent and the balance of solvent.

8. The liquid formulation according to claim 6, comprising the following components in parts by weight, based on 100 parts by weight: 2-4 parts of comprehensive fruit and vegetable enzyme liquid, 0.1-0.2 part of yerba mate extract, 0.08-0.15 part of ginseng peptide, 0.08-0.15 part of medlar, 0.05-0.1 part of rhizoma polygonati, 0.02-0.06 part of spearmint extract, 0.02-0.05 part of turmeric, 4-9 parts of sweetening agent, 0.1-0.5 part of acidity regulator, 0.08-0.15 part of flavoring agent and the balance of solvent.

9. A method for preparing a liquid formulation according to any one of claims 7 to 8, comprising the steps of:

(1) Weighing the components in parts by weight;

(2) Mixing yerba mate extract, ginseng peptide, medlar, sealwort, spearmint extract and turmeric uniformly, adding a solvent, stirring and heating until the mixture is completely dissolved to obtain a mixture A;

(3) Uniformly mixing the sweetening agent and the acidity regulator, adding the solvent, stirring and heating until the mixture is transparent to obtain a mixture B;

(4) And (3) uniformly stirring and mixing the mixture A obtained in the step (1), the mixture B obtained in the step (2), the comprehensive fruit and vegetable enzyme liquid, the flavoring agent and the solvent, homogenizing and canning to obtain the liquid preparation.

10. The method for preparing a liquid preparation according to claim 9, wherein the heating temperature in the step (2) is 50 to 60 ℃; in the step (3), the heating temperature is 50-60 ℃; in the step (4), the stirring speed is 15-20r/min.