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CN115192893A - Left ventricle auxiliary device - Google Patents

Left ventricle auxiliary device Download PDF

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Publication number
CN115192893A
CN115192893A CN202210725360.2A CN202210725360A CN115192893A CN 115192893 A CN115192893 A CN 115192893A CN 202210725360 A CN202210725360 A CN 202210725360A CN 115192893 A CN115192893 A CN 115192893A
Authority
CN
China
Prior art keywords
blood
blood pump
chamber
control device
air
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202210725360.2A
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Chinese (zh)
Inventor
于洋
曾玉杰
柳弘历
于文渊
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beijing Yuewei Medical Technology Co ltd
Original Assignee
Beijing Yuewei Medical Technology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beijing Yuewei Medical Technology Co ltd filed Critical Beijing Yuewei Medical Technology Co ltd
Priority to CN202210725360.2A priority Critical patent/CN115192893A/en
Publication of CN115192893A publication Critical patent/CN115192893A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10Location thereof with respect to the patient's body
    • A61M60/104Extracorporeal pumps, i.e. the blood being pumped outside the patient's body
    • A61M60/117Extracorporeal pumps, i.e. the blood being pumped outside the patient's body for assisting the heart, e.g. transcutaneous or external ventricular assist devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20Type thereof
    • A61M60/247Positive displacement blood pumps
    • A61M60/253Positive displacement blood pumps including a displacement member directly acting on the blood
    • A61M60/268Positive displacement blood pumps including a displacement member directly acting on the blood the displacement member being flexible, e.g. membranes, diaphragms or bladders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/40Details relating to driving
    • A61M60/424Details relating to driving for positive displacement blood pumps
    • A61M60/427Details relating to driving for positive displacement blood pumps the force acting on the blood contacting member being hydraulic or pneumatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/50Details relating to control
    • A61M60/508Electronic control means, e.g. for feedback regulation
    • A61M60/515Regulation using real-time patient data
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/50Details relating to control
    • A61M60/508Electronic control means, e.g. for feedback regulation
    • A61M60/515Regulation using real-time patient data
    • A61M60/531Regulation using real-time patient data using blood pressure data, e.g. from blood pressure sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80Constructional details other than related to driving
    • A61M60/835Constructional details other than related to driving of positive displacement blood pumps
    • A61M60/837Aspects of flexible displacement members, e.g. shapes or materials

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Mechanical Engineering (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • External Artificial Organs (AREA)

Abstract

The invention provides a left ventricle auxiliary device, which comprises a blood pump, wherein the blood pump is ellipsoidal and the interior of the blood pump is hollow; the diaphragm is arranged in the blood pump and divides the interior of the blood pump into a blood chamber and an air chamber, and the blood chamber is connected with a pipeline; the pressure change control device is communicated with the air chamber pipeline and connected with the pipeline, and is configured to be capable of identifying blood pressure signals or electrocardiogram signals and adjusting the air volume in the air chamber according to the blood pressure signals or the electrocardiogram signals. According to the invention, the ellipsoidal blood pump is arranged, the diaphragm is arranged in the blood pump, the blood pump is divided into the air chamber and the blood chamber, the pressure change control device is used for identifying a blood pressure signal or an electrocardiogram signal to adjust the air volume in the air chamber so as to adjust the blood volume in the blood chamber, and the adjustment effect is good; the single pipeline is arranged, so that the number of pipelines through which blood flows is reduced, and the problems of hemolysis, thrombus and the like can be effectively prevented.

Description

Left ventricle auxiliary device
Technical Field
The invention relates to the technical field of medical instruments, in particular to a left ventricle auxiliary device.
Background
Clinically, patients with symptoms such as cardiogenic shock, refractory heart failure, incapability of separating from an extracorporeal circulation machine after heart operation, fatal arrhythmia, transition support before heart transplantation, rescue treatment of patients with high-risk acute myocardial infarction, support of high-risk interventional operation and the like all need extracorporeal mechanical circulation support treatment to save lives.
The mechanical circulation auxiliary device is an auxiliary circulation method which directly leads blood of an atrium or a ventricle to the outside of the body through a mechanical device, and the blood is transferred to an arterial system through an auxiliary pump or directly flows from the ventricle to the root of an aorta, so that the heart load is reduced, the work of the ventricle is replaced, the heart is partially or completely replaced, and the blood supply of important visceral organs in the body is ensured. The mechanical circulation is mainly divided into a power device, a blood storage device and a blood transportation pipeline. Currently, the only mechanically-assisted circulatory devices that are available domestically are extracorporeal membrane pulmonary oxygenation (ECMO), intra-aortic balloon counterpulsation (IABP), and mini-ventricular assist devices (Impella).
The ECMO system is characterized in that two catheters are respectively implanted into an aorta and a main vein, the catheter in the main vein is connected with an external artificial lung, the external artificial lung is connected with an axial flow pump or a pulse pump, and then is connected with the catheter in the aorta, and the ECMO system has the defects that the external artificial lung is required to be established, the structure is complex, the pulmonary circulation is interrupted, thrombus in a pulmonary duct is easily formed, and severe bleeding is easily caused. The IABP is a long saccule inserted into the aorta, the saccule inflates and exhausts with the beating of the heart to enhance the myocardial blood supply, and the defect is that the operation of the saccule is unstable depending on the function of the ventricle. The medicine has no obvious effect on the long-term prognosis of patients, does not reduce the 30-day mortality of cardiogenic shock patients, and does not recommend the conventional use of IABP any more in national guidelines. The Impella system consists of a catheter which is punctured to the left ventricle through the femoral artery, the front end of the catheter is provided with a cage-shaped blood inflow port, the ascending aorta is provided with an outflow port, an axial flow pump is arranged between the inflow port and the outflow port, and the left ventricle blood is guided to the aorta. Therefore, in the existing mechanical circulatory assist device, the space in the blood pump cannot be effectively adjusted, and the blood pump has a plurality of flow pipelines, so that the problems of thrombus and the like are easily caused.
Disclosure of Invention
The invention provides a left chamber auxiliary device, which is used for solving the defect that a mechanical circulation auxiliary device in the prior art is complex in structure.
The present invention provides a left ventricle assist device, including:
the blood pump is ellipsoidal and the interior of the blood pump is hollow;
the diaphragm is arranged in the blood pump and divides the interior of the blood pump into a blood chamber and an air chamber, and the blood chamber is connected with a pipeline;
the pressure change control device is communicated with the air chamber pipeline and connected with the pipeline, and is configured to be capable of identifying blood pressure signals or electrocardiogram signals and adjusting the air volume in the air chamber according to the blood pressure signals or the electrocardiogram signals.
According to the present invention, there is provided a left ventricular assist device, comprising:
a detection component configured to be capable of detecting blood pressure in the conduit and an electrocardiogram signal;
and the gas control device is electrically connected with the detection assembly and is configured to perform air suction or air exhaust in response to the blood pressure signal or the electrocardiogram signal.
According to the left ventricle auxiliary device provided by the invention, the detection component is a pressure sensor;
the gas control device is an air pump or a fan.
According to the left ventricle auxiliary device provided by the invention, the diaphragm is arranged on the long shaft of the blood pump.
According to the left chamber auxiliary device provided by the invention, the diaphragm is an elastic diaphragm and can expand or contract along with the increase or decrease of the air volume of the air chamber.
According to the left chamber auxiliary device provided by the invention, the pipeline comprises a first pipe body and a second pipe body, and the pipe diameter of the second pipe body is larger than that of the first pipe body.
According to the left ventricle auxiliary device provided by the invention, the pressure change control device is connected with the second pipe body.
According to the present invention, there is provided a left ventricular assist device, further comprising:
a hard shell adapted to the blood pump.
According to the left chamber auxiliary device provided by the invention, the hard shell is in a hemispherical shape, and the hard shell is fixedly connected with the air chamber.
According to the left chamber auxiliary device provided by the invention, the hard shell is adhered to the outer side of the air chamber.
According to the left ventricle auxiliary device provided by the invention, the ellipsoidal blood pump is arranged, the diaphragm is arranged in the blood pump to divide the blood pump into the air chamber and the blood chamber, the pressure change control device is used for identifying the blood pressure signal or the electrocardiogram signal to adjust the air volume in the air chamber so as to adjust the blood volume in the blood chamber, and the adjusting effect is good; the single pipeline is arranged, so that the number of pipelines through which blood flows is reduced, and the problems of hemolysis, thrombus and the like can be effectively prevented.
Drawings
In order to more clearly illustrate the technical solutions of the present invention or the prior art, the drawings needed for the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and those skilled in the art can also obtain other drawings according to the drawings without creative efforts.
Fig. 1 is a schematic structural view of a left ventricle auxiliary device provided by the present invention.
Reference numerals:
1: left ventricle auxiliary device, 2: blood pump, 21: blood chamber, 22: air chamber, 3: diaphragm, 4: pressure change control device, 41: gas control device, 5: pipe, 51: first pipe, 52: second pipe, 6: and (4) hardening.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings, and it is obvious that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The left chamber auxiliary device of the present invention will be described with reference to fig. 1
As shown in fig. 1, the present invention provides a left ventricle assisting device 1, which comprises a blood pump 2, a diaphragm 3 and a pressure-variable control device 4, wherein the blood pump 2 is used for communicating with the left ventricle in the human body to store blood and provide power for the blood flow, the pressure-variable control device 4 is used for regulating the air volume in the blood pump 2 according to a blood pressure signal or an electrocardiogram signal, and further drives the diaphragm 3 to move to regulate the blood storage volume in the blood pump 2.
Further, blood pump 2 is the inside cavity of ellipsoid and blood pump 2, and diaphragm 3 sets up inside blood pump 2, divide into blood room 22 and air chamber 21 with the inside of blood pump 2, and blood room 22 is used for saving blood, and air chamber 21 is used for ventilating, sets up blood room 22 to the inner space that the ellipsoid can increase blood pump 2, and then increases blood room 22's the blood storage volume and the gas storage volume of air chamber 21, and the blood pump 2 of ellipsoid can also avoid inside blood to remain in a large number, and then avoids forming the thrombus. Be connected with pipeline 5 on the blood room 22, the flow has blood in the pipeline 5, is provided with the pipeline mouth on the blood room 22 and is connected with pipeline 5, like this, makes the pipeline that blood flowed through reduce through setting up single pipeline mouth, can prevent effectively that hemolysis, thrombus scheduling problem from taking place. The pressure change control device 4 is communicated with the air chamber 21 and is connected with the pipeline 5, and is configured to recognize the blood pressure signal or the electrocardiogram signal and adjust the air quantity in the air chamber 21 according to the blood pressure signal or the electrocardiogram signal.
It should be understood that the pressure-variable control device 4 has a detection function, a signal identification function and an air supply and air exhaust function, so that the pressure-variable control device 4 firstly detects blood pressure or electrocardio and generates signals, then identifies the blood pressure signals or the electrocardio signals and supplies air or exhausts air according to the blood pressure signals or the electrocardio signals to adjust the air quantity in the air chamber 21 and further adjust the blood storage quantity in the blood chamber 22.
Further, the pressure-change control device 4 includes a detection component configured to be able to detect the blood pressure in the conduit 5 and an electrocardiogram signal; specifically, the detection component is a pressure sensor or an electrode plate, the pressure sensor detects the blood pressure condition and generates a pressure signal, and the electrode plate acts on the human body to detect the electrocardio condition of the human body and generate an electrocardio signal and can form an electrocardiogram on the pressure-variable control device 4.
The pressure-variable control device 4 further comprises a gas control device 41, the gas control device 41 is electrically connected with the detection component, the gas control device 41 can be arranged in the pressure-variable control device 4 or can be separated from the pressure-variable control device 4, and the gas control device 41 can respond to a blood pressure signal or an electrocardiogram signal to perform air suction or air exhaust. Specifically, the gas control device 41 may be an air pump or a blower, the gas control device 41 is in communication with the air chamber 21, when the gas control device 41 inflates the air chamber 21, the gas amount in the air chamber 21 increases, and the diaphragm 3 deforms due to the increase of the gas amount, so that the internal space of the air chamber 21 also increases, and accordingly, the internal space of the blood chamber 22 decreases, and the blood storage amount of the blood chamber 22 also decreases. Similarly, when the gas control device 41 evacuates, the internal space of the gas chamber 21 decreases and the internal space of the blood chamber 22 increases.
The pressure change control device 4 sets the air exhaust and exhaust volume of the air chamber 21 according to the cardiac output assisting degree set by the user, namely the cardiac output value increased by the instrument. In the contraction period, the pressure change control device 4 can identify the starting point of the arterial blood pressure wave or the starting point of the QRS wave group of the electrocardiogram and extract helium with corresponding volume according to the air extraction amount; the pressure-variable control device 4 can recognize t-wave on arterial blood pressure dicrotic notch or electrocardiogram during diastole, and discharge helium gas according to the exhaust gas amount, and when the arterial blood pressure and electrocardiogram cannot be recognized, the pressure-variable control device 4 can be set to a fixed rate to provide asynchronous support. When the left ventricle is in the contraction phase, the pressure variable control device 4 is used for evacuating helium in the air chamber 21, and blood is sucked to the blood chamber 22 by virtue of negative pressure; when the left ventricle is in diastole, the pressure variable control device 4 fills the helium gas into the gas chamber 21, the gas chamber 21 expands, and the volume of the blood chamber 22 decreases.
In the present application, the diaphragm 3 is disposed on the long axis of the blood pump 2. Namely, the diaphragm 3 is flatly arranged on the long shaft of the ellipsoidal blood pump 2 to separate the air outlet chamber 21 and the blood chamber 22, so as to ensure that the maximum volume change is obtained under the minimum motion amplitude of the diaphragm 3, the diaphragm 3 is made of elastic material and can be elastically deformed along with the change of the air volume in the air chamber 21, and thus, the variable volume of the air chamber 21 or the blood chamber 22 in unit time is large, and the response is fast.
The pipe 5 includes a first pipe 51 and a second pipe 52, and the pipe diameter of the second pipe 52 is larger than that of the first pipe 51. Through setting up the pipe diameter that the pipe diameter of second body 52 is greater than the pipe diameter of first body 51, can make the space grow when blood gets into blood pump 2 or leaves from blood pump 2, avoided the emergence of thrombus effectively.
The pressure-variable control device 4 is connected with the second pipe body 52, and specifically, a detection component of the pressure-variable control device 4 is connected at the joint of the second pipe body 52 and the first pipe body 51, so that the blood pressure in the pipeline 5 can be better detected.
The left ventricle auxiliary device 1 further comprises a hard shell 6, the hard shell 6 is matched with the blood pump 2, specifically, the hard shell 6 is in a hemispherical shape, the shape of the hard shell 6 is matched with the shape of the outer side of the blood pump 2, and the hard shell 6 is adhered to the outer side of the air chamber 21 so that the position between the hard shell 6 and the blood pump 2 is fixed.
Finally, it should be noted that: the above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.

Claims (10)

1. A left ventricular assist device, comprising:
the blood pump is ellipsoidal and the interior of the blood pump is hollow;
the diaphragm is arranged in the blood pump and divides the interior of the blood pump into a blood chamber and an air chamber, and the blood chamber is connected with a pipeline;
the pressure-variable control device is communicated with the air chamber pipeline and connected with the pipeline, and is configured to be capable of identifying blood pressure signals or electrocardiogram signals and adjusting the air volume in the air chamber according to the blood pressure signals or the electrocardiogram signals.
2. A left ventricular assist device according to claim 1, wherein the dilatant control device comprises:
a detection component connected with a human body or a pipeline and configured to be capable of detecting blood pressure in the pipeline and electrocardiogram signals;
and the gas control device is electrically connected with the detection assembly and is configured to perform air suction or air exhaust in response to the blood pressure signal or the electrocardiogram signal.
3. A left ventricular assist device according to claim 2,
the detection assembly is a pressure sensor;
the gas control device is an air pump or a fan and is arranged in the pressure change control device.
4. The blood pump according to any of claims 1 to 3,
the diaphragm is arranged on the long shaft of the blood pump.
5. The blood pump of claim 4,
the diaphragm is an elastic diaphragm and can expand or contract along with the increase or decrease of the air quantity of the air chamber.
6. A left ventricular assist device according to claim 1,
the pipeline includes first body and second body, the pipe diameter of second body is greater than the pipe diameter of first body.
7. A left ventricular assist device according to claim 6,
the pressure change control device is connected with the second pipe body.
8. The left ventricular assist device of claim 1, further comprising:
a hard shell adapted to the blood pump.
9. A left ventricular assist device according to claim 8,
the hard shell is of a hemispherical shape and is fixedly connected with the air chamber.
10. The left ventricular assist device of claim 9,
the hard shell is bonded to the outside of the air chamber.
CN202210725360.2A 2022-06-23 2022-06-23 Left ventricle auxiliary device Pending CN115192893A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210725360.2A CN115192893A (en) 2022-06-23 2022-06-23 Left ventricle auxiliary device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210725360.2A CN115192893A (en) 2022-06-23 2022-06-23 Left ventricle auxiliary device

Publications (1)

Publication Number Publication Date
CN115192893A true CN115192893A (en) 2022-10-18

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115492747A (en) * 2022-11-17 2022-12-20 季华实验室 Fluid drive type diaphragm pump and adjusting system thereof
WO2025011166A1 (en) * 2023-07-10 2025-01-16 北京悦唯医疗科技有限责任公司 Left ventricular assist device
CN120168856A (en) * 2025-05-20 2025-06-20 脉柯斯医疗科技(绍兴)有限公司 An interventional ventricular assist device and ventricular assist membrane pump

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109939282A (en) * 2019-04-23 2019-06-28 四川大学 A percutaneous left ventricular assisted circulatory system
WO2021094359A1 (en) * 2019-11-11 2021-05-20 Berlin Heart Gmbh Pump system, control unit and method for operating a pump system
CN113967316A (en) * 2021-11-22 2022-01-25 山东瑞安泰医疗技术有限公司 Implanted aorta counterpulsation device with pressure sensing automatic regulation and control function
CN114177515A (en) * 2021-11-22 2022-03-15 山东瑞安泰医疗技术有限公司 An extracorporeal left ventricular assist device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109939282A (en) * 2019-04-23 2019-06-28 四川大学 A percutaneous left ventricular assisted circulatory system
WO2021094359A1 (en) * 2019-11-11 2021-05-20 Berlin Heart Gmbh Pump system, control unit and method for operating a pump system
CN113967316A (en) * 2021-11-22 2022-01-25 山东瑞安泰医疗技术有限公司 Implanted aorta counterpulsation device with pressure sensing automatic regulation and control function
CN114177515A (en) * 2021-11-22 2022-03-15 山东瑞安泰医疗技术有限公司 An extracorporeal left ventricular assist device

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115492747A (en) * 2022-11-17 2022-12-20 季华实验室 Fluid drive type diaphragm pump and adjusting system thereof
CN115492747B (en) * 2022-11-17 2023-03-10 季华实验室 A fluid-driven diaphragm pump and its regulating system
WO2025011166A1 (en) * 2023-07-10 2025-01-16 北京悦唯医疗科技有限责任公司 Left ventricular assist device
CN120168856A (en) * 2025-05-20 2025-06-20 脉柯斯医疗科技(绍兴)有限公司 An interventional ventricular assist device and ventricular assist membrane pump

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