CN115192265A

CN115192265A - Backbone defect filling fusion body based on personalized 3D printing

Info

Publication number: CN115192265A
Application number: CN202210830250.2A
Authority: CN
Inventors: 刘非
Original assignee: Shanghai Arigin Medical Co ltd
Current assignee: Shanghai Arigin Medical Co ltd
Priority date: 2022-07-15
Filing date: 2022-07-15
Publication date: 2022-10-18

Abstract

The present application discloses a diaphysis defect filling fusion based on personalized 3D printing, including a solid part and a porous part, the solid part is arranged around the porous part; the porous part includes a first joint surface, a second joint surface, a The three joint surfaces and the back curved surface, the first joint surface, the second joint surface, the third joint surface and the back curved surface are surrounded to form a closed space. The second engagement surface includes a first side and a second side, the first engagement surface adjoins the second engagement surface at the first side, and the third engagement surface adjoins the second engagement surface at the second side. The second joint surface includes a third side and a fourth side, the back curved surface and the second joint surface are adjacent to the third side and the fourth side, and the back curved surface is adjacent to the first joint surface and the third joint surface. The filling fusion of the present application has a good matching effect with the bone defect space. The back surface of the filled fusion body matches the original bone surface of the patient, does not affect the growth of the bone surface tissue, and retains the physiological characteristics and mechanical properties of the bone surface.

Description

Backbone defect filling fusion body based on personalized 3D printing

Technical Field

The application relates to the field of orthopedic surgery implants, in particular to a backbone defect filling fusion body based on personalized 3D printing.

Background

Bone defects are often caused by trauma, inflammation, tumors, or surgical debridement. Bone defect treatment is difficult, the period is long, complications are more, great economic, psychological and social pressure is brought to patients, and the life quality of the patients is seriously affected. If the bone defect range reaches the critical bone defect length, namely 1.5-2.5 times of the circumference of the backbone or more than 1/10 of the length, the maximum capability of self-repairing bone is exceeded, and the defect can not be healed by self. At this time, surgical intervention is required to repair the large bone defect. At present, the clinical means for treating bone defects is mainly bone grafting. The bone grafting materials commonly used in clinic include autologous bones, allogeneic bones, synthetic biomaterials and the like.

However, bone grafting using autologous or allogeneic bone currently suffers from various degrees of drawbacks:

autologous bone grafting is the removal of qualified bone tissue from other parts of the patient's own body, which adds additional trauma and time to the procedure. For patients with large bone defect volumes, it is difficult to find a satisfactory bone on its own. Therefore, the bone source of the autologous bone is limited, and even cannot be found.

The allogeneic bone transplantation may cause the propagation of blood-borne diseases and the interference of immune response to bone healing. In addition, allogeneic bone has only osteoconductive and no osteoinductive effects, and fracture healing after transplantation is relatively slow.

At present, titanium alloy materials are generally adopted clinically as artificial bone substitutes for bone transplantation, but the elastic modulus of metal materials is not matched with that of bones, stress shielding is easily generated after the materials are implanted, and the risk of secondary fracture is increased while bone absorption is caused. Also, conventional machining processes do not allow the implant to match the physical dimensions of the bone defect space, which can result in wear or other unwanted trauma.

Although it is possible to use trabecular bone structures or similar porous structures in the prior art to adjust the modulus of elasticity to match the human bone, for larger bone defects (above 4 cm), the strength of the porous structure is problematic, affecting the stability of the implant.

Therefore, those skilled in the art are dedicated to develop a bone defect filling fusion based on personalized 3D printing to solve the technical problems in the prior art.

Disclosure of Invention

In order to achieve the above object, the present application provides a diaphysis defect filling fusion body based on personalized 3D printing, including a solid portion and a porous portion, wherein the solid portion is circumferentially disposed around the porous portion; the porous portion includes first composition surface, second composition surface, third composition surface and back curved surface, first composition surface, the second composition surface, the third composition surface and the back curved surface surrounds formation enclosure space.

Further, the second engagement surface includes a first side and a second side, the first engagement surface and the second engagement surface being contiguous at the first side, the third engagement surface and the second engagement surface being contiguous at the second side.

Further, the first bonding surface and the third bonding surface are not parallel, the first bonding surface is not perpendicularly disposed with respect to the second bonding surface, and the third bonding surface is not perpendicularly disposed with respect to the second bonding surface.

Further, the second joint surface includes a third side and a fourth side, the back curved surface is adjacent to the second joint surface on the third side and the fourth side, and the back curved surface is adjacent to the first joint surface and the third joint surface.

Further, the back curved surface intersects with the first joint surface, the second joint surface and the third joint surface to form a closed back curve.

Further, the solid portion extends along the back curve.

Further, the solid portion includes an opening provided in a middle portion of the porous portion, and the opening penetrates the porous portion in a direction perpendicular to the second joint surface.

Further, 2 openings are provided for receiving fasteners.

Furthermore, the first joint surface, the second joint surface and the third joint surface are all attached to the plane of the bone defect space.

Further, the back curve coincides with the outer surface of the bone defect space.

Compared with the prior art, the technical scheme of the application has the following technical effects at least:

1. the filling fusion body provided by the application is manufactured based on a personalized 3D printing process, and the problem of material acquisition does not exist. Both the shape and size depend on the exact preoperative plan for the three-dimensional model reconstruction of the surgical site. Therefore, the filling fusion body has good matching effect with the bone defect space. The back curved surface of the filling fusion body is matched with the surface of the original bone of a patient, so that the growth of the surface tissue of the bone is not influenced, and the physiological characteristics and the mechanical property of the surface of the bone are kept.

2. The application provides a fill fusion, adjust elasticity modulus in order to reduce stress shielding through the porous portion of trabecular bone structure, thereby be favorable to the bone to grow into simultaneously and improve the joining effect.

3. The filled fusion provided by the application is suitable for maintaining the stability of the fusion in bone defects with the length of more than 4cm by arranging a solid part around the porous part to increase the overall strength of the fusion.

4. The application provides a fill fusion, is provided with two openings that are used for holding the fastener in the middle part, through supplementary fixed fusion of fasteners such as screw.

The conception, specific structure and technical effects of the present application will be further described in conjunction with the accompanying drawings so that the purpose, features and effects of the present application can be fully understood.

Drawings

FIG. 1 is a schematic three-dimensional appearance of an embodiment of the present application;

FIG. 2 is a schematic structural view of the embodiment of FIG. 1;

FIG. 3 is a schematic side view of an embodiment of the present application;

FIG. 4 is a schematic structural diagram of the embodiment of FIG. 3;

FIG. 5 is a side view schematic of an embodiment of the present application;

FIG. 6 is a schematic view of an embodiment of the present application being secured to a bone.

Detailed Description

The preferred embodiments of the present application will be described below with reference to the accompanying drawings so that the technical contents thereof will be more clearly understood. The present application may be embodied in many different forms of embodiments and the scope of the present application is not limited to only the embodiments set forth herein.

Examples

Fig. 1 shows a backbone defect filling fusion body based on personalized 3D printing provided in this embodiment. The filler fusion is used for repairing the diaphysis defect on the inner side of the femur. Fig. 3 is a side view of the present embodiment. The structure is shown in fig. 2 and 4. The porous body comprises a solid part 1 and a porous part 2, wherein the solid part 1 is arranged around the porous part 2 in a surrounding manner. The porous portion 2 includes a first bonding surface 21, a second bonding surface 22, a third bonding surface 23, and a back curved surface 24. The first bonding surface 21, the second bonding surface 22, and the third bonding surface 23 are all flat surfaces, and the back curved surface 24 is a non-flat curved surface. The first joint surface 21, the second joint surface 22, the third joint surface 23 and the back curved surface 24 surround to form a closed space. For clarity, the second bonding surface 22 is taken as a bottom surface to be viewed from above (as viewed in fig. 2), and the outline of the present embodiment is substantially rectangular, and includes a first side a, a second side B, a third side C and a fourth side D. The first joint surface 21 adjoins the second joint surface 22 at a first side a, and the third joint surface 23 adjoins the second joint surface 22 at a second side B. The first engagement surface 21 is at a non-perpendicular angle to the second engagement surface 22 and the third engagement surface 23 is at a non-perpendicular angle to the second engagement surface 22. Preferably, the first joint surface 21 and the third joint surface 23 are both at an obtuse angle with respect to the second joint surface 22, so that the whole of the present embodiment has a boat-shaped structure with the second joint surface 22 as a bottom surface.

When the second bonding surface 22 is the bottom surface, the back curved surface 24 is disposed at the top. The back curve 24 adjoins the first joint face 21 at the first side a and forms a first curve 11 at the adjoining; the back curve 24 adjoins the third joint surface 23 at the second side B and forms a second curve 12 at the abutment; the back curved surface 24 is adjacent to the second joining surface 22 at the third side C and the fourth side D, and forms the third curved line 13 and the fourth curved line 14 at the adjacent positions. The first curve 11, the second curve 12, the third curve 13, and the fourth curve 14 constitute a closed back curve as an outer contour of the present embodiment. The solid portion 1 extends in the back curve direction, that is, the solid portion 1 is disposed along the first curve 11, the second curve 12, the third curve 13, and the fourth curve 14. For filler fusions used to repair a bony defect of the shaft, they are typically larger in size (greater than 4cm in length), and so providing the outer contour as a solid metal structure helps to increase the overall structural strength.

An opening 15 is provided inside the porous portion 2. The opening 15 extends through the entire filled blend from the back curve 24 to the second joining face 22 in a direction perpendicular to the second joining face 22. Preferably, a plurality of openings 15 are provided. Preferably, the opening 15 is cylindrical, the inner wall of which is provided with a thread. The opening 15 may receive a threaded fastener (e.g., a fastening screw) therethrough to effect securement of the present embodiment. To ensure strength at the opening 15, the opening 15 is a metal solid structure.

The solid portion 1 and the porous portion 2 of the present embodiment are both made of a titanium alloy. Preferably, the porous portion 2 is a trabecular bone structure. Fig. 4 is a side sectional view of the present embodiment. The angle of view of the cross-sectional view is from the second side B to the first side a. The first bonding surface 21, the second bonding surface 22, and the third bonding surface 23 are all porous structures. The middle portion of the back curve 24 is porous in area and solid in metal in the back curve. Since this embodiment is typically used to fill a femoral shaft defect, and is therefore larger in size (greater than 4cm in length), the porous structure becomes more and more problematic in strength as the size and volume become larger. Thus, the solid metal structure is arranged around the filling fusion body in a surrounding mode, and the effect of increasing the overall strength is achieved.

Fig. 6 is a schematic structural view of the present embodiment when installed in a femur having a bone defect. It can be seen that the bone defect space has three planes, since the bone defect created by the surgical procedure is created by the cutting of the surgical instrument. By precise preoperative planning, the size of the filling fusion device matches the size of the bone defect space, so the first engagement surface 21, second engagement surface 22, and third engagement surface 23 of the present embodiment fit exactly into the three planes of the bone defect space. Meanwhile, the three joint surfaces jointed with the bone defect space plane are all of bone trabecula structures, which are beneficial to the growth of bone cells, thereby providing better binding force. The back curve 24 is shaped to match the native outer surface of the femur so that it does not interfere with the growth of other tissue surrounding the bone, while also preserving the native physiological characteristics and mechanical properties of the femur. For example, the solid body 1 of the present embodiment further includes a projection 16 for replacing the small rotor originally in this position. In other similar embodiments, back curve 24 may also be designed to be curved to match the location of the bone defect. A fastening screw 17 is provided in the opening 15 to achieve fixation of the filled fusion relative to the bone defect space.

In the above description of the present application, it should be noted that the words "one side" or "the other side", "top surface" or "bottom surface" and the like indicate orientations or positional relationships based on orientations or positional relationships shown in the drawings or orientations or positional relationships where the product is conventionally placed in use, and are used for convenience of description and simplicity of description only, and do not indicate or imply that the positions or elements referred to must have a specific orientation, be constructed in a specific orientation, and operate, and thus, should not be construed as limiting the present application. Moreover, the terms "first," "second," and the like are used solely to distinguish one from another and are not to be construed as indicating or implying relative importance. Furthermore, the use of the terms "parallel" or "perpendicular" does not limit the structures to be strictly parallel or perpendicular in the mathematical sense, but rather may be formed to be non-strictly parallel or perpendicular with some tolerance under industrial production circumstances.

The foregoing detailed description of the preferred embodiments of the present application. It should be understood that numerous modifications and variations can be devised by those skilled in the art in light of the present teachings without departing from the inventive concepts. Therefore, the technical solutions available to those skilled in the art through logic analysis, reasoning and limited experiments based on the concepts of the present application should be within the scope of protection defined by the claims.

Claims

1. A diaphysis defect filling fusion based on personalized 3D printing, comprising a solid part and a porous part, wherein the solid part is circumferentially arranged around the porous part; the porous part comprises a first joint surface, the second joint surface, the third joint surface and the back curved surface, the first joint surface, the second joint surface, the third joint surface and the back curved surface surround and form a closed space.

2 . The diaphyseal defect filling fusion based on personalized 3D printing according to claim 1 , wherein the second joint surface comprises a first side and a second side, and the first joint surface is connected to the first joint surface. 3 . Two engagement surfaces abut at the first side, and the third engagement surface abuts the second engagement surface at the second side.

3 . The diaphyseal defect filling fusion body based on personalized 3D printing according to claim 2 , wherein the first joint surface and the third joint surface are not parallel to each other, and the first joint surface is opposite to the The second joint surface is arranged non-vertically, and the third joint surface is arranged non-vertically with respect to the second joint surface.

4 . The diaphysis defect filling fusion body based on personalized 3D printing according to claim 3 , wherein the second joint surface includes a third side and a fourth side, and the back surface is jointed with the second side. 5 . A face adjoins the fourth side on the third side, and the back curved surface adjoins the first and third engagement surfaces.

5 . The diaphysis defect filling fusion body based on personalized 3D printing according to claim 4 , wherein the back curved surface is connected to the first joint surface, the second joint surface, and the third joint surface. 6 . Intersect to form a closed back curve.

6 . The diaphyseal defect filling fusion based on personalized 3D printing according to claim 5 , wherein the solid portion extends along the back curve. 7 .

7. The diaphysis defect filling fusion body based on personalized 3D printing according to claim 6, wherein the solid part comprises an opening, the opening is arranged in the middle of the porous part, and the opening extends perpendicular to the The direction of the second bonding surface penetrates through the porous portion.

8 . The diaphysis defect filling fusion body based on personalized 3D printing according to claim 6 , wherein two of the openings are provided, and the openings are used for accommodating fasteners. 9 .

9 . The diaphyseal defect filling fusion body based on personalized 3D printing according to claim 1 , wherein the first joint surface, the second joint surface, and the third joint surface are all connected to the bone defect space. 10 . flat fit.

10 . The diaphyseal defect filling and fusion body based on personalized 3D printing according to claim 1 , wherein the dorsal curved surface coincides with the outer surface of the bone defect space. 11 .