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CN114681575A - External washing lotion for treating sheep pediculosis and preparation method thereof - Google Patents

External washing lotion for treating sheep pediculosis and preparation method thereof Download PDF

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Publication number
CN114681575A
CN114681575A CN202011609450.2A CN202011609450A CN114681575A CN 114681575 A CN114681575 A CN 114681575A CN 202011609450 A CN202011609450 A CN 202011609450A CN 114681575 A CN114681575 A CN 114681575A
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CN
China
Prior art keywords
parts
pediculosis
decoction
washing lotion
filtrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202011609450.2A
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Chinese (zh)
Inventor
刘鼎阔
刘芳
李源
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Dingzheng Xinxing Biotechnology Tianjin Co ltd
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Dingzheng Xinxing Biotechnology Tianjin Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Dingzheng Xinxing Biotechnology Tianjin Co ltd filed Critical Dingzheng Xinxing Biotechnology Tianjin Co ltd
Priority to CN202011609450.2A priority Critical patent/CN114681575A/en
Publication of CN114681575A publication Critical patent/CN114681575A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/904Stemonaceae (Stemona family), e.g. croomia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)

Abstract

A topical lotion for treating pediculosis ovis comprises radix Stemonae, herba Chenopodii, Bulbus Lycoridis Radiatae, and Glycyrrhrizae radix. In the invention, the components are weighed according to the measurement, water is added for decoction twice, the filtrate is mixed and filtered, the filtrate is concentrated, ethanol is added for standing, the ethanol is recovered after filtration, the concentration is carried out, the water is added for constant volume, and the finished product is obtained after refrigeration and filtration. When the washing lotion is used, the washing lotion is diluted with water according to the proportion of 1:10 and then washed twice a day for 3-5 days continuously, the skin damage of sheep is reduced, the itching feeling is weakened, and the growth and the reproduction of lice are inhibited.

Description

External washing lotion for treating sheep pediculosis and preparation method thereof
Technical Field
The invention belongs to the technical field of prevention and treatment of sheep parasitic diseases, and particularly relates to an external washing lotion for treating sheep pediculosis and a preparation method thereof.
Background
Sheep lice are permanently parasitic ectoparasitic diseases and have strict animal owner specificity. Infestation by lice can cause chronic dermatitis characterized by persistent irritation, itching, rubbing and gnawing of the wool. Lice are likely to occur in all sheep fed countries. Three lice will infect sheep, the chewing sheep lice (sheep wool lice), the blood sucking sheep palaemon lice (whitefly) and the sheep paw palaemon lice (pediculus humanus). Pediculosis infection can cause considerable loss due to decreased body condition, slower growth and impaired coat quality in sheep.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provide the external lotion for treating the sheep pediculosis, which is scientific in proportioning, good in treatment effect and free of toxic and side effects.
The technical scheme adopted by the invention is as follows: the external washing lotion for treating sheep pediculosis is characterized in that: the composition comprises the following components in parts by weight:
15-20 parts of radix stemonae;
15-20 parts of chenopodium ambrosioides;
11-15 parts of lycoris radiata;
5-10 parts of liquorice.
The invention also aims to provide a preparation method of the external washing lotion for treating sheep pediculosis, which is characterized by comprising the following steps: the method comprises the following steps:
weighing radix stemonae, chenopodium ambrosioides, lycoris radiata and liquorice according to measurement, and adding the weighed materials into clear water with the weight being 10 times that of the materials to decoct the materials twice;
secondly, after the first decoction is carried out for 2 hours, filtrate is reserved, and the dregs of a decoction are added with clear water with the weight of 10 times of that of the dregs of a decoction for the second decoction for 1.5 hours, and the filtrate is reserved;
thirdly, combining the filtrates obtained in the two steps, concentrating the filtered filtrate to a proper amount, adding ethanol to enable the ethanol content to be 75%, uniformly stirring, and standing for 24 hours;
fourthly, filtering the product obtained in the step three, recovering ethanol, concentrating to a proper amount, adding water to a constant volume, refrigerating for 24 hours, and filtering to obtain a finished product.
Another object of the present invention is to provide a method for using a lotion for external use for treating pediculosis ovis, which is characterized in that: the medicament according to claim 1 or 2 is used for washing an affected part of a sheep, and the washing liquid is diluted with water according to a ratio of 1:10 and then washed twice a day for 3-5 days continuously.
The invention has the advantages and positive effects that:
according to the invention, radix stemonae, chenopodium ambrosioides, lycoris radiata and liquorice are weighed according to the measurement, water is added for decocting twice, the filtrates are merged and filtered, the filtrate is concentrated, ethanol is added for standing, the ethanol is recovered after filtering, the concentration is carried out, the water is added for constant volume, and the finished product is obtained after refrigeration and filtration. When the washing lotion is used, the washing lotion is diluted with water according to the proportion of 1:10 and then washed twice a day for 3-5 days continuously, the skin injury of sheep is relieved, the itching feeling is weakened, and the growth and the reproduction of lice are inhibited.
Detailed Description
The present invention is further illustrated by the following examples, which are intended to be illustrative, not limiting and are not intended to limit the scope of the invention.
The invention discloses an external washing lotion for treating sheep pediculosis, which is characterized in that: the composition comprises the following components in parts by weight:
15-20 parts of radix stemonae;
15-20 parts of chenopodium ambrosioides;
11-15 parts of lycoris radiate;
5-10 parts of liquorice.
More preferred embodiments are: the composition comprises the following components in parts by weight:
20 parts of radix stemonae;
20 parts of chenopodium ambrosioides;
15 parts of lycoris radiate;
and 5 parts of liquorice.
The medicine of the invention comprises:
radix Stemonae is sweet and bitter in taste and slightly warm in nature, and can be used for treating head louse, body louse, enterobiasis, and pudendal pruritus; the Chenopodium ambrosioides has the effects of removing dampness, killing parasites to relieve itching, and promoting blood circulation to remove swelling, and belongs to the insecticidal antipruritic medicine; the lycoris has the effects of detoxifying, resolving masses, relieving swelling and killing insects; the liquorice has the effects of relieving drug toxicity and harmonizing the medicines.
Example 1
The externally applied lotion for treating sheep pediculosis and the preparation method thereof comprise the following components:
20 parts of stemona root, 20 parts of chenopodium ambrosioides, 15 parts of lycoris radiata and 5 parts of liquorice
Weighing radix stemonae, chenopodium ambrosioides, lycoris radiata and liquorice according to measurement, and adding the weighed materials into clear water with the weight being 10 times that of the materials to decoct the materials twice;
secondly, after the first decoction is carried out for 2 hours, filtrate is reserved, and the dregs of a decoction are added with clear water with the weight of 10 times of that of the dregs of a decoction for the second decoction for 1.5 hours, and the filtrate is reserved;
thirdly, combining the filtrates obtained in the two steps, concentrating the filtered filtrate to a proper amount, adding ethanol to enable the ethanol content to be 75%, uniformly stirring, and standing for 24 hours;
fourthly, filtering the product obtained in the step three, recovering ethanol, concentrating to a proper amount, adding water to a constant volume, refrigerating for 24 hours, and filtering to obtain a finished product.
Example 2
The external lotion for treating the sheep pediculosis consists of the following components:
15 parts of radix stemonae, 20 parts of chenopodium ambrosioides, 10 parts of lycoris radiata and 5 parts of liquorice
The preparation method of the traditional Chinese medicine compound preparation is carried out according to the embodiment 1.
Example 3
The external washing lotion for treating the pediculosis ovis consists of the following components:
20 parts of stemona root, 15 parts of chenopodium ambrosioides, 10 parts of lycoris radiata and 5 parts of liquorice
The preparation method of the traditional Chinese medicine compound preparation is carried out according to the embodiment 1.
The pharmaceutical agent according to claim 1 or 2 is administered to a diseased sheep with established pediculosis in sheep in Hebei province. When the washing lotion is used, the washing lotion is diluted with water according to the proportion of 1:10 and then washed twice a day for 3-5 days continuously, the skin injury of sheep is relieved, the itching feeling is weakened, and the growth and the reproduction of lice are inhibited.

Claims (4)

1. The external washing lotion for treating sheep pediculosis is characterized in that: the composition comprises the following components in parts by weight:
15-20 parts of radix stemonae;
15-20 parts of chenopodium ambrosioides;
11-15 parts of lycoris radiate;
5-10 parts of liquorice.
2. A topical lotion for the treatment of ovine pediculosis according to claim 1, characterized in that: the composition comprises the following components in parts by weight:
20 parts of radix stemonae;
20 parts of chenopodium ambrosioides;
15 parts of lycoris radiate;
and 5 parts of liquorice.
3. A topical lotion for the treatment of pediculosis ovis according to claim 1 or 2, characterized in that: the method comprises the following steps:
weighing radix stemonae, chenopodium ambrosioides, lycoris radiata and liquorice according to measurement, and adding the weighed materials into clear water with the weight being 10 times that of the materials to decoct the materials twice;
secondly, after the first decoction is carried out for 2 hours, filtrate is reserved, and the dregs of a decoction are added with clear water with the weight of 10 times of that of the dregs of a decoction for the second decoction for 1.5 hours, and the filtrate is reserved;
thirdly, combining the filtrates obtained in the two steps, concentrating the filtered filtrate to a proper amount, adding ethanol to enable the ethanol content to be 75%, uniformly stirring, and standing for 24 hours;
fourthly, filtering the product obtained in the step three, recovering ethanol, concentrating to a proper amount, adding water to a constant volume, refrigerating for 24 hours, and filtering to obtain a finished product.
4. The external washing lotion for treating sheep pediculosis is characterized in that: the agent of claim 1 or 2, which is diluted with water at a ratio of 1:10 and washed twice a day for 3 to 5 days.
CN202011609450.2A 2020-12-31 2020-12-31 External washing lotion for treating sheep pediculosis and preparation method thereof Pending CN114681575A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202011609450.2A CN114681575A (en) 2020-12-31 2020-12-31 External washing lotion for treating sheep pediculosis and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202011609450.2A CN114681575A (en) 2020-12-31 2020-12-31 External washing lotion for treating sheep pediculosis and preparation method thereof

Publications (1)

Publication Number Publication Date
CN114681575A true CN114681575A (en) 2022-07-01

Family

ID=82132410

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202011609450.2A Pending CN114681575A (en) 2020-12-31 2020-12-31 External washing lotion for treating sheep pediculosis and preparation method thereof

Country Status (1)

Country Link
CN (1) CN114681575A (en)

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Application publication date: 20220701