CN103800618A - Oral pills for treating waist and leg arthralgia and preparation method thereof - Google Patents
Oral pills for treating waist and leg arthralgia and preparation method thereof Download PDFInfo
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Abstract
Description
技术领域 technical field
本发明属于中药制剂技术领域,主要涉及一种治疗腰腿关节痛的口服丸剂及其制备方法。 The invention belongs to the technical field of traditional Chinese medicine preparations, and mainly relates to an oral pill for treating lumbago and leg joint pain and a preparation method thereof.
背景技术 Background technique
随着时代的快速发展,人们的压力越来越大,腰腿关节痛成为很常见的多发症,其发病率甚高,严重影响着人们的身体健康和正常的工作、生活、学习和劳动,现有的治疗方法也有很多种,有理疗、化疗、推拿等治疗方法,但上述治疗方法止痛效果慢,治疗时间长,治疗效果欠佳。目前,也有使用药物进行治疗的,现虽有多种腰腿关节痛的中西药物,西药制剂多是一些镇痛止痛药物,且激素类运用较多,长期使用对人体危害很大,中药制剂普遍存在疗效不确切,不能除去病根,疗效并不尽人意,而且费用高,服用不方便,难以有效坚持。 With the rapid development of the times, people are under more and more pressure. Lumbar and leg joint pain has become a very common multiple disease with a high incidence rate, which seriously affects people's health and normal work, life, study and labor. Existing treatment methods also have many kinds, such as physical therapy, chemotherapy, massage and other treatment methods, but the above-mentioned treatment methods have slow analgesic effect, long treatment time, and poor therapeutic effect. At present, there are also medicines for treatment. Although there are many kinds of Chinese and Western medicines for waist and leg joint pain, most of the western medicine preparations are analgesic and analgesic medicines, and hormones are used more. Long-term use is very harmful to the human body. Traditional Chinese medicine preparations are generally There is indefinite curative effect, can not remove the root of the disease, curative effect is unsatisfactory, and cost is high, takes inconvenient, is difficult to effectively adhere to.
发明内容 Contents of the invention
本发明的目的是针对现有技术中的不足,提供一种治疗腰腿关节痛的口服丸剂,该丸剂具有补肝肾、强筋骨、除风湿、补气活血、止痛消炎之功效,对腰椎肩盘突出、急性腰损伤、滑膜炎、腰腿疼痛、骨质增生等症治疗效果显著,采用口服制剂,见效快,标本兼治,治愈率高。 The object of the present invention is to address the deficiencies in the prior art, to provide an oral pill for the treatment of joint pain in the waist and legs. Disc herniation, acute lumbar injury, synovitis, lumbago and leg pain, hyperosteogeny and other diseases have a remarkable therapeutic effect. Oral preparations are used, which can take effect quickly, treat both symptoms and root causes, and have a high cure rate.
本发明实现上述目的采用的技术方案是:一种治疗腰腿关节痛的口服丸剂,按照重量份数由以下组分制成:鹿茸2-4份、红参12-18份、杜仲16-24份、山药16-24份、草灵仙12-18份、当归16-24份、黄芪16-24份、肉桂12-18份、藤艽27-33份、红花15-21份、乳香12-18份、没药12-18份、全虫16-24份、三七12-18份、鸡血藤15-21份、双钩藤12-18份、川断16-24份、木瓜27-33份、牛夕15-21份、蜈蚣22-28份、桂枝14-18份、川姜活15-21份、独活14-18份、甘草7-13份、马钱子16-24份和蜂蜜120-160份; The technical scheme adopted by the present invention to achieve the above object is: an oral pill for treating pain in the waist and legs, which is made of the following components in parts by weight: 2-4 parts of velvet antler, 12-18 parts of red ginseng, 16-24 parts of Eucommia 16-24 parts of Chinese yam, 12-18 parts of grass spirit, 16-24 parts of angelica, 16-24 parts of astragalus, 12-18 parts of cinnamon, 27-33 parts of rattan, 15-21 parts of safflower, 12 parts of frankincense -18 parts, 12-18 parts of myrrh, 16-24 parts of whole worm, 12-18 parts of Panax notoginseng, 15-21 parts of Caulis Spatholobus, 12-18 parts of Bicaria, 16-24 parts of Chuan Duan, 27- parts of papaya 33 parts, 15-21 parts of Niuxi, 22-28 parts of Centipede, 14-18 parts of Guizhi, 15-21 parts of Chuan Jianghuo, 14-18 parts of Duhuo, 7-13 parts of Licorice, 16-24 parts of Nuxynum and honey 120-160 parts;
所述的马钱子为经过与甘草和绿豆共同水煮后拣出并用砖压制得到的炮制马钱子。 The nux nux mentioned above is the processed nux nux that is picked out after being boiled with licorice and mung beans and pressed with bricks.
所述的一种治疗腰腿关节痛的口服丸剂的制备方法,包括以下步骤: A preparation method of an oral pill for the treatment of lumbago and leg joint pain, comprising the following steps:
步骤一、按照重量份数分别取鹿茸2-4份、红参12-18份、杜仲16-24份、山药16-24份、草灵仙12-18份、当归16-24份、黄芪16-24份、肉桂12-18份、藤艽27-33份、红花15-21份、乳香12-18份、没药12-18份、全虫16-24份、三七12-18份、鸡血藤15-21份、双钩藤12-18份、川断16-24份、木瓜27-33份、牛夕15-21份、蜈蚣22-28份、桂枝14-18份、川姜活15-21份、独活14-18份、甘草7-13份和蜂蜜120-160份,备用; Step 1. Take 2-4 parts of pilose antler, 12-18 parts of red ginseng, 16-24 parts of Eucommia, 16-24 parts of Chinese yam, 12-18 parts of grass spirit, 16-24 parts of angelica, and 16 parts of astragalus according to the parts by weight. -24 parts, 12-18 parts of cinnamon, 27-33 parts of rattan, 15-21 parts of safflower, 12-18 parts of frankincense, 12-18 parts of myrrh, 16-24 parts of whole worm, 12-18 parts of Panax notoginseng , Caulis Spatholobus 15-21 parts, Bicaria 12-18 parts, Chuan Duan 16-24 parts, Papaya 27-33 parts, Niuxi 15-21 parts, Centipede 22-28 parts, Guizhi 14-18 parts, Sichuan 15-21 servings of ginger, 14-18 servings of solitary, 7-13 servings of licorice and 120-160 servings of honey, set aside;
将蜂蜜除外的原料分别进行热风干燥,并粉碎至100目,然后置于混合机中混合均匀,得到混合粉末; Dry the raw materials except honey separately with hot air, and pulverize them to 100 meshes, and then place them in a mixer and mix them evenly to obtain mixed powders;
取马钱子原材料,置入煎煮器中,分别加入与马钱子同重量的甘草和绿豆,然后加水进行煎煮,煎煮至绿豆衣脱落并漂浮在液面,煎煮完成后拣出马钱子,除去毛茸,得到熟马钱子,将熟马钱子铺在由两层砌墙砖铺设而成的平台上,并在熟马钱子上面压设砌墙砖,在通风条件下保持10-16d后,取出干燥,然后按照重量份数取16-24份,并粉碎至100目,得到炮制后的马钱子粉,备用; Take the nuxychnium raw material, put it into a fryer, add licorice and mung bean of the same weight as the nuxynum respectively, and then add water to decoct until the mung bean coat falls off and floats on the liquid surface, after the decoction is completed, pick out the nuxynum Qianzi, remove the fur, get cooked nuyony, spread the cooked nuyony on a platform made of two-layer wall bricks, and press the wall bricks on the cooked nuyony, under ventilated conditions After keeping it for 10-16 days, take it out and dry it, then take 16-24 parts according to the parts by weight, and pulverize it to 100 mesh to obtain processed Nuxychnami powder, which is set aside;
步骤二、将步骤一取出的蜂蜜置于练蜜锅内,在温度为30-50℃条件下进行加热,加热过程中除去浮沫,每次除去浮沫后在搅拌速度为60r/min的条件下搅拌蜂蜜20-60s,直至不再出现浮沫即完成加热,得到练蜜,备用; Step 2. Put the honey taken out in step 1 into the honey pot and heat it at a temperature of 30-50°C. During the heating process, remove the froth. Stir the honey for 20-60s, until no more froth appears, then the heating is completed, and the honey is obtained, which is set aside;
步骤三、将步骤一得到的马钱子粉加入到步骤二得到的练蜜中,在为30-50℃条件下搅拌混合均匀,然后趁热加入步骤一得到的混合粉末,混合均匀后制成丸剂,即完成治疗腰腿关节痛的口服丸剂的制备。 Step 3. Add the nuxe seed powder obtained in step 1 to the refined honey obtained in step 2, stir and mix evenly at 30-50°C, then add the mixed powder obtained in step 1 while it is hot, and mix evenly to make Pills, that is, the preparation of oral pills for the treatment of low back and leg joint pain is completed.
本发明的有益效果 Beneficial effects of the present invention
其一、本发明具有补肝肾、强筋骨、除风湿、补气活血、止痛消炎之功效,对腰椎肩盘突出、急性腰损伤、滑膜炎、腰腿疼痛、骨质增生等症治疗效果显著,采用口服制剂,见效快,标本兼治,治愈率达到90%以上。 One, the present invention has the effects of invigorating liver and kidney, strengthening muscles and bones, removing rheumatism, invigorating qi and promoting blood circulation, relieving pain and reducing inflammation, and has therapeutic effects on diseases such as lumbar disc herniation, acute lumbar injury, synovitis, lumbago and leg pain, and hyperosteogeny Significantly, the oral preparation is adopted, and the effect is quick, and both symptoms and root causes are treated, and the cure rate reaches more than 90%.
其二、本发明中,鹿茸、红参、杜仲、山药、当归、黄芪等主补气血、滋阴益阳、强肾益肝,草灵仙、肉桂、藤艽、红花等主祛风除湿,解毒止痛,通筋活络,两部分药物相互协同,使本发明中的补肝肾、强筋骨、除风湿、补气活血、止痛消炎之功效显著。 Second, in the present invention, pilose antler, red ginseng, eucommia, Chinese yam, angelica, astragalus, etc. are mainly for nourishing qi and blood, nourishing yin and yang, strengthening kidney and liver; , detoxification and pain relief, dredging tendons and activating collaterals, and the two parts of medicine cooperate with each other, so that the effects of nourishing liver and kidney, strengthening muscles and bones, removing rheumatism, invigorating qi and blood circulation, relieving pain and reducing inflammation in the present invention are remarkable.
其三、本发明的药物中采用了马钱子,马钱子在治疗腰腿关节痛方面效果显著,但是毒性较强,本发明提供的药物制备方法中将马钱子先用甘草和绿豆煎煮,再用砌墙砖压制,经过这样的炮制一方面使马钱子的毒性去除的较完善,减小口服的副作用,另一方面能够促进马钱子作用的发挥,增强本发明口服制剂的药效。 Its three, in the medicine of the present invention, adopted Semen Nuxyma Chin, Semen Nuxyma Chin is effective in the treatment of lumbago and leg arthralgia, but toxicity is stronger, in the medicine preparation method provided by the invention, Semen Nuxyma Chin is first decocted with Radix Glycyrrhizae and mung bean Boil, and then suppress with wall bricks, through such concocting on the one hand make the toxicity of Nuxychnium to remove more perfect, reduce the side effect of oral administration, can promote the performance of the effect of Nuxychon on the other hand, strengthen the oral preparation of the present invention efficacy.
具体实施方式 Detailed ways
一种治疗腰腿关节痛的口服丸剂,按照重量份数由以下组分制成:鹿茸2-4份、红参12-18份、杜仲16-24份、山药16-24份、草灵仙12-18份、当归16-24份、黄芪16-24份、肉桂12-18份、藤艽27-33份、红花15-21份、乳香12-18份、没药12-18份、全虫16-24份、三七12-18份、鸡血藤15-21份、双钩藤12-18份、川断16-24份、木瓜27-33份、牛夕15-21份、蜈蚣22-28份、桂枝14-18份、川姜活15-21份、独活14-18份、甘草7-13份、马钱子16-24份和蜂蜜120-160份; An oral pill for treating lumbago and leg joint pain, which is made of the following components in parts by weight: 2-4 parts of velvet antler, 12-18 parts of red ginseng, 16-24 parts of Eucommia ulmoides, 16-24 parts of yam, and cao lingxian 12-18 parts, 16-24 parts of angelica, 16-24 parts of astragalus, 12-18 parts of cinnamon, 27-33 parts of rattan, 15-21 parts of safflower, 12-18 parts of frankincense, 12-18 parts of myrrh, 16-24 parts of whole worm, 12-18 parts of Panax notoginseng, 15-21 parts of Miltonia, 12-18 parts of Bicaria, 16-24 parts of Chuan Duan, 27-33 parts of papaya, 15-21 parts of Niuxi, centipede 22-28 parts, 14-18 parts of Guizhi, 15-21 parts of Chuanjianghuo, 14-18 parts of Duhuo, 7-13 parts of licorice, 16-24 parts of Nuxynum and 120-160 parts of honey;
所述的马钱子为经过与甘草和绿豆共同水煮后拣出并用砖压制得到的炮制马钱子。 The nux nux mentioned above is the processed nux nux that is picked out after being boiled with licorice and mung beans and pressed with bricks.
所述的一种治疗腰腿关节痛的口服丸剂的制备方法,包括以下步骤: A preparation method of an oral pill for the treatment of lumbago and leg joint pain, comprising the following steps:
步骤一、按照重量份数分别取鹿茸2-4份、红参12-18份、杜仲16-24份、山药16-24份、草灵仙12-18份、当归16-24份、黄芪16-24份、肉桂12-18份、藤艽27-33份、红花15-21份、乳香12-18份、没药12-18份、全虫16-24份、三七12-18份、鸡血藤15-21份、双钩藤12-18份、川断16-24份、木瓜27-33份、牛夕15-21份、蜈蚣22-28份、桂枝14-18份、川姜活15-21份、独活14-18份、甘草7-13份和蜂蜜120-160份,备用; Step 1. Take 2-4 parts of pilose antler, 12-18 parts of red ginseng, 16-24 parts of Eucommia, 16-24 parts of Chinese yam, 12-18 parts of grass spirit, 16-24 parts of angelica, and 16 parts of astragalus according to the parts by weight. -24 parts, 12-18 parts of cinnamon, 27-33 parts of rattan, 15-21 parts of safflower, 12-18 parts of frankincense, 12-18 parts of myrrh, 16-24 parts of whole worm, 12-18 parts of Panax notoginseng , Caulis Spatholobus 15-21 parts, Bicaria 12-18 parts, Chuan Duan 16-24 parts, Papaya 27-33 parts, Niuxi 15-21 parts, Centipede 22-28 parts, Guizhi 14-18 parts, Sichuan 15-21 servings of ginger, 14-18 servings of solitary, 7-13 servings of licorice and 120-160 servings of honey, set aside;
将蜂蜜除外的原料分别进行热风干燥,并粉碎至100目,然后置于混合机中混合均匀,得到混合粉末; Dry the raw materials except honey separately with hot air, and pulverize them to 100 meshes, and then place them in a mixer and mix them evenly to obtain mixed powders;
取马钱子原材料,置入煎煮器中,分别加入与马钱子同重量的甘草和绿豆,然后加水进行煎煮,煎煮至绿豆衣脱落并漂浮在液面,煎煮完成后拣出马钱子,除去毛茸,得到熟马钱子,将熟马钱子铺在由两层砌墙砖铺设而成的平台上,并在熟马钱子上面压设砌墙砖,在通风条件下保持10-16d后,取出干燥,然后按照重量份数取16-24份,并粉碎至100目,得到炮制后的马钱子粉,备用; Take the nuxychnium raw material, put it into a fryer, add licorice and mung bean of the same weight as the nuxynum respectively, and then add water to decoct until the mung bean coat falls off and floats on the liquid surface, after the decoction is completed, pick out the nuxynum Qianzi, remove the fur, get cooked nuyony, spread the cooked nuyony on a platform made of two-layer wall bricks, and press the wall bricks on the cooked nuyony, under ventilated conditions After keeping it for 10-16 days, take it out and dry it, then take 16-24 parts according to the parts by weight, and pulverize it to 100 mesh to obtain processed Nuxychnami powder, which is set aside;
步骤二、将步骤一取出的蜂蜜置于练蜜锅内,在温度为30-50℃条件下进行加热,加热过程中除去浮沫,每次除去浮沫后在搅拌速度为60r/min的条件下搅拌蜂蜜20-60s,直至不再出现浮沫即完成加热,得到练蜜,备用; Step 2. Put the honey taken out in step 1 into the honey pot and heat it at a temperature of 30-50°C. During the heating process, remove the froth. Stir the honey for 20-60s, until no more froth appears, then the heating is completed, and the honey is obtained, which is set aside;
步骤三、将步骤一得到的马钱子粉加入到步骤二得到的练蜜中,在为30-50℃条件下搅拌混合均匀,然后趁热加入步骤一得到的混合粉末,混合均匀后制成丸剂,即完成治疗腰腿关节痛的口服丸剂的制备。 Step 3. Add the nuxe seed powder obtained in step 1 to the refined honey obtained in step 2, stir and mix evenly at 30-50°C, then add the mixed powder obtained in step 1 while it is hot, and mix evenly to make Pills, that is, the preparation of oral pills for the treatment of low back and leg joint pain is completed.
以下结合具体实施例对本发明做进一步说明:The present invention will be further described below in conjunction with specific embodiment:
实施例1:Example 1:
一种治疗腰腿关节痛的口服丸剂,按照重量份数由以下组分制成:鹿茸2份、红参12份、杜仲16份、山药16份、草灵仙12份、当归16份、黄芪16份、肉桂12份、藤艽27份、红花15份、乳香12份、没药12份、全虫16份、三七12份、鸡血藤15份、双钩藤12份、川断16份、木瓜27份、牛夕15份、蜈蚣22份、桂枝14份、川姜活15份、独活14份、甘草7份、马钱子16份和蜂蜜120份。 An oral pill for treating low back and leg joint pain, which is made of the following components in parts by weight: 2 parts of velvet antler, 12 parts of red ginseng, 16 parts of Eucommia ulmoides, 16 parts of Chinese yam, 12 parts of cao lingxian, 16 parts of angelica, and astragalus 16 parts, 12 parts of cinnamon, 27 parts of rattan, 15 parts of safflower, 12 parts of frankincense, 12 parts of myrrh, 16 parts of whole insect, 12 parts of Panax notoginseng, 15 parts of Milletanus, 12 parts of bicaria, 16 parts of Chuan Duan 27 parts of papaya, 15 parts of Niu Xi, 22 parts of centipede, 14 parts of cassia twig, 15 parts of Chuan Jiang Huo, 14 parts of Du Huo, 7 parts of licorice, 16 parts of Nuxe chinensis and 120 parts of honey.
所述的一种治疗腰腿关节痛的口服丸剂的制备方法,包括以下步骤: A preparation method of an oral pill for the treatment of lumbago and leg joint pain, comprising the following steps:
步骤一、按照上述重量份数分别取鹿茸、红参、杜仲、山药、草灵仙、当归、黄芪、肉桂、藤艽、红花、乳香、没药、全虫、三七、鸡血藤、双钩藤、川断、木瓜、牛夕、蜈蚣、桂枝、川姜活、独活、甘草和蜂蜜,备用; Step 1. Take deer antler, red ginseng, Eucommia ulmoides, yam, cayenne, angelica, astragalus, cinnamon, rattan, safflower, frankincense, myrrh, whole worm, notoginseng, Caulis Spatholobus, Double Uncaria, Chuanduan, Papaya, Niuxi, Centipede, Guizhi, Chuanjianghuo, Duhuo, Licorice and Honey, set aside;
将蜂蜜除外的原料分别进行热风干燥,并粉碎至100目,然后置于混合机中混合均匀,得到混合粉末; Dry the raw materials except honey separately with hot air, and pulverize them to 100 meshes, and then place them in a mixer and mix them evenly to obtain mixed powders;
取马钱子原材料,置入煎煮器中,分别加入与马钱子同重量的甘草和绿豆,然后加水进行煎煮,煎煮至绿豆衣脱落并漂浮在液面,煎煮完成后拣出马钱子,除去毛茸,得到熟马钱子,将熟马钱子铺在由两层砌墙砖铺设而成的平台上,并在熟马钱子上面压设砌墙砖,在通风条件下保持10d后,取出干燥,然后按照上述重量份数称取,并粉碎至100目,得到炮制后的马钱子粉,备用; Take the nuxychnium raw material, put it into a fryer, add licorice and mung bean of the same weight as the nuxynum respectively, and then add water to decoct until the mung bean coat falls off and floats on the liquid surface, after the decoction is completed, pick out the nuxynum Qianzi, remove the fur, get cooked nuyony, spread the cooked nuyony on a platform made of two-layer wall bricks, and press the wall bricks on the cooked nuyony, under ventilated conditions After keeping it for 10 days, take it out and dry it, then weigh it according to the above-mentioned parts by weight, and crush it to 100 mesh to obtain processed Nuxychnami powder, which is set aside;
步骤二、将步骤一取出的蜂蜜置于练蜜锅内,在温度为30℃条件下进行加热,加热过程中除去浮沫,每次除去浮沫后在搅拌速度为60r/min的条件下搅拌蜂蜜20s,直至不再出现浮沫即完成加热,得到练蜜,备用; Step 2. Put the honey taken out in step 1 into the honey pot and heat it at 30°C. During the heating process, remove the froth. After removing the froth each time, stir at a stirring speed of 60r/min. Honey for 20s, until no more froth appears, then the heating is completed, and honey is obtained, which is set aside;
步骤三、将步骤一得到的马钱子粉加入到步骤二得到的练蜜中,在为30℃条件下搅拌混合均匀,然后趁热加入步骤一得到的混合粉末,混合均匀后制成丸剂,即完成治疗腰腿关节痛的口服丸剂的制备。 Step 3: Add the Nuxychee powder obtained in Step 1 to the refined honey obtained in Step 2, stir and mix evenly at 30°C, then add the mixed powder obtained in Step 1 while it is hot, and make a pill after mixing evenly. Promptly complete the preparation of the oral pill for the treatment of lumbago and leg arthralgia.
实施例2:Example 2:
一种治疗腰腿关节痛的口服丸剂,按照重量份数由以下组分制成:鹿茸4份、红参18份、杜仲24份、山药24份、草灵仙18份、当归24份、黄芪24份、肉桂18份、藤艽33份、红花21份、乳香18份、没药18份、全虫24份、三七18份、鸡血藤21份、双钩藤18份、川断24份、木瓜33份、牛夕21份、蜈蚣28份、桂枝18份、川姜活21份、独活18份、甘草13份、马钱子24份和蜂蜜160份。 An oral pill for treating low back and leg joint pain, which is made of the following components in parts by weight: 4 parts of velvet antler, 18 parts of red ginseng, 24 parts of Eucommia ulmoides, 24 parts of Chinese yam, 18 parts of cao lingxian, 24 parts of angelica, and astragalus 24 parts, 18 parts of cinnamon, 33 parts of rattan, 21 parts of safflower, 18 parts of frankincense, 18 parts of myrrh, 24 parts of whole insects, 18 parts of Panax notoginseng, 21 parts of Milletanus, 18 parts of bicaria, 24 parts of Chuan Duan 33 parts of Chinese papaya, 21 parts of Niu Xi, 28 parts of centipede, 18 parts of cassia twig, 21 parts of Chuan Jianghuo, 18 parts of Duhuo, 13 parts of licorice, 24 parts of Nuxe chinensis and 160 parts of honey.
所述的一种治疗腰腿关节痛的口服丸剂的制备方法,包括以下步骤: A preparation method of an oral pill for the treatment of lumbago and leg joint pain, comprising the following steps:
步骤一、按照上述重量份数分别取鹿茸、红参、杜仲、山药、草灵仙、当归、黄芪、肉桂、藤艽、红花、乳香、没药、全虫、三七、鸡血藤、双钩藤、川断、木瓜、牛夕、蜈蚣、桂枝、川姜活、独活、甘草和蜂蜜,备用; Step 1. Take deer antler, red ginseng, Eucommia ulmoides, yam, cayenne, angelica, astragalus, cinnamon, rattan, safflower, frankincense, myrrh, whole worm, notoginseng, Caulis Spatholobus, Double Uncaria, Chuanduan, Papaya, Niuxi, Centipede, Guizhi, Chuanjianghuo, Duhuo, Licorice and Honey, set aside;
将蜂蜜除外的原料分别进行热风干燥,并粉碎至100目,然后置于混合机中混合均匀,得到混合粉末; Dry the raw materials except honey separately with hot air, and pulverize them to 100 meshes, and then place them in a mixer and mix them evenly to obtain mixed powders;
取马钱子原材料,置入煎煮器中,分别加入与马钱子同重量的甘草和绿豆,然后加水进行煎煮,煎煮至绿豆衣脱落并漂浮在液面,煎煮完成后拣出马钱子,除去毛茸,得到熟马钱子,将熟马钱子铺在由两层砌墙砖铺设而成的平台上,并在熟马钱子上面压设砌墙砖,在通风条件下保持16d后,取出干燥,然后按照上述重量份数称取,并粉碎至100目,得到炮制后的马钱子粉,备用; Take the nuxychnium raw material, put it into a fryer, add licorice and mung bean of the same weight as the nuxynum respectively, and then add water to decoct until the mung bean coat falls off and floats on the liquid surface, after the decoction is completed, pick out the nuxynum Qianzi, remove the fur, get cooked nuyony, spread the cooked nuyony on a platform made of two-layer wall bricks, and press the wall bricks on the cooked nuyony, under ventilated conditions After keeping it for 16 days, take it out and dry it, then weigh it according to the above-mentioned parts by weight, and crush it to 100 mesh to obtain processed Nuxychnami powder, which is set aside;
步骤二、将步骤一取出的蜂蜜置于练蜜锅内,在温度为50℃条件下进行加热,加热过程中除去浮沫,每次除去浮沫后在搅拌速度为60r/min的条件下搅拌蜂蜜60s,直至不再出现浮沫即完成加热,得到练蜜,备用; Step 2. Put the honey taken out in step 1 into a honey pot and heat it at a temperature of 50°C. During the heating process, remove the froth. After removing the froth each time, stir at a stirring speed of 60r/min. Honey for 60s, until no more froth appears, then the heating is completed, and the honey is obtained, which is set aside;
步骤三、将步骤一得到的马钱子粉加入到步骤二得到的练蜜中,在为50℃条件下搅拌混合均匀,然后趁热加入步骤一得到的混合粉末,混合均匀后制成丸剂,即完成治疗腰腿关节痛的口服丸剂的制备。 Step 3. Add the nuxychnium powder obtained in step 1 to the refined honey obtained in step 2, stir and mix evenly at 50°C, then add the mixed powder obtained in step 1 while it is hot, and make a pill after mixing evenly. Promptly complete the preparation of the oral pill for the treatment of lumbago and leg arthralgia.
实施例3:Example 3:
一种治疗腰腿关节痛的口服丸剂,按照重量份数由以下组分制成:鹿茸3份、红参15份、杜仲20份、山药20份、草灵仙15份、当归20份、黄芪20份、肉桂15份、藤艽30份、红花18份、乳香15份、没药15份、马钱子20份、全虫20份、三七15份、鸡血藤18份、双钩藤15份、川断20份、木瓜30份、牛夕18份、蜈蚣25份、桂枝16份、川姜活18份、独活16份、甘草10份和蜂蜜140份。 An oral pill for treating lumbago and leg joint pain, which is made of the following components in parts by weight: 3 parts of velvet antler, 15 parts of red ginseng, 20 parts of Eucommia ulmoides, 20 parts of Chinese yam, 15 parts of cao lingxian, 20 parts of angelica, and astragalus 20 parts, 15 parts of cinnamon, 30 parts of rattan, 18 parts of safflower, 15 parts of frankincense, 15 parts of myrrh, 20 parts of nuxychonzi, 20 parts of whole worm, 15 parts of Panax notoginseng, 18 parts of Milletah, bicaria 15 parts, 20 parts Chuan Duan, 30 parts papaya, 18 parts Niu Xi, 25 parts centipede, 16 parts Guizhi, 18 parts Chuanjianghuo, 16 parts Duhuo, 10 parts licorice and 140 parts honey.
所述的一种治疗腰腿关节痛的口服丸剂的制备方法,包括以下步骤: A preparation method of an oral pill for the treatment of lumbago and leg joint pain, comprising the following steps:
步骤一、按照上述重量份数分别取鹿茸、红参、杜仲、山药、草灵仙、当归、黄芪、肉桂、藤艽、红花、乳香、没药、全虫、三七、鸡血藤、双钩藤、川断、木瓜、牛夕、蜈蚣、桂枝、川姜活、独活、甘草和蜂蜜,备用; Step 1. Take deer antler, red ginseng, Eucommia ulmoides, yam, cayenne, angelica, astragalus, cinnamon, rattan, safflower, frankincense, myrrh, whole worm, notoginseng, Caulis Spatholobus, Double Uncaria, Chuanduan, Papaya, Niuxi, Centipede, Guizhi, Chuanjianghuo, Duhuo, Licorice and Honey, set aside;
将蜂蜜除外的原料分别进行热风干燥,并粉碎至100目,然后置于混合机中混合均匀,得到混合粉末; Dry the raw materials except honey separately with hot air, and pulverize them to 100 meshes, and then place them in a mixer and mix them evenly to obtain mixed powders;
取马钱子原材料,置入煎煮器中,分别加入与马钱子同重量的甘草和绿豆,然后加水进行煎煮,煎煮至绿豆衣脱落并漂浮在液面,煎煮完成后拣出马钱子,除去毛茸,得到熟马钱子,将熟马钱子铺在由两层砌墙砖铺设而成的平台上,并在熟马钱子上面压设砌墙砖,在通风条件下保持13d后,取出干燥,然后按照上述重量份数称取,并粉碎至100目,得到炮制后的马钱子粉,备用; Take the nuxychnium raw material, put it into a fryer, add licorice and mung bean of the same weight as the nuxynum respectively, and then add water to decoct until the mung bean coat falls off and floats on the liquid surface, after the decoction is completed, pick out the nuxynum Qianzi, remove the fur, get cooked nuyony, spread the cooked nuyony on a platform made of two-layer wall bricks, and press the wall bricks on the cooked nuyony, under ventilated conditions After keeping it for 13 days, take it out and dry it, then weigh it according to the above-mentioned parts by weight, and crush it to 100 mesh to obtain processed Nuxychnami powder, which is set aside;
步骤二、将步骤一取出的蜂蜜置于练蜜锅内,在温度为40℃条件下进行加热,加热过程中除去浮沫,每次除去浮沫后在搅拌速度为60r/min的条件下搅拌蜂蜜40s,直至不再出现浮沫即完成加热,得到练蜜,备用; Step 2. Put the honey taken out in step 1 into the honey pot and heat it at 40°C. During the heating process, remove the froth. After removing the froth each time, stir at a stirring speed of 60r/min. Honey for 40s, until no more froth appears, then the heating is completed, and honey is obtained, which is set aside;
步骤三、将步骤一得到的马钱子粉加入到步骤二得到的练蜜中,在为40℃条件下搅拌混合均匀,然后趁热加入步骤一得到的混合粉末,混合均匀后制成丸剂,即完成治疗腰腿关节痛的口服丸剂的制备。 Step 3, add the nuxychnium powder obtained in step 1 to the refined honey obtained in step 2, stir and mix evenly under the condition of 40°C, then add the mixed powder obtained in step 1 while it is hot, and make a pill after mixing evenly, Promptly complete the preparation of the oral pill for the treatment of lumbago and leg arthralgia.
试验例数据Test case data
本发明自研制以来,记录在案的已经有300例患者使用,其有效率达99%,痊愈率达90%。 Since the present invention was developed, 300 cases of patients have been recorded to use it, and its effective rate reaches 99%, and the recovery rate reaches 90%.
本发明的服用方法为:每天早晚各1次,一次3丸,15天为一个疗程。 The taking method of the present invention is: each morning and evening every day, 3 pills each time, 15 days as a course of treatment.
疗效标准: Curative effect standard:
痊愈:服用此药后症状消失,停药后观察半个月以上,未复发; Recovery: the symptoms disappeared after taking the drug, and there was no recurrence after observation for more than half a month after stopping the drug;
有效:服用此药后症状明显减轻; Effective: After taking this medicine, the symptoms are obviously relieved;
无效:服用此药后症状未有明显减轻; Invalid: The symptoms have not been significantly relieved after taking this medicine;
典型病例: Typical cases:
病例1 :魏某,男,家住河南省新密市七里岗镇惠沟村,患腰椎间盘突出和腿痛,经多次治疗均未痊愈,服用此药20天后痊愈,至今未复发。 Case 1: Wei, male, who lives in Huigou Village, Qiligang Town, Xinmi City, Henan Province, suffered from lumbar disc herniation and leg pain. He was not cured after repeated treatments. He recovered after taking this medicine for 20 days and has not recurred so far.
病例2:李某,女,家住河南省新密市曲梁镇下牛村,患腰椎间盘突出,服用此药18天后痊愈,至今未复发。 Case 2: Li, female, who lives in Xianiu Village, Quliang Town, Xinmi City, Henan Province, suffered from lumbar disc herniation. She recovered after taking this medicine for 18 days and has not recurred so far.
病例3:张某,女,家住河南省新密市大隗镇双楼村,患腰椎间盘突,服用此药18天后痊愈,至今未复发。 Case 3: Zhang, female, who lives in Shuanglou Village, Dakai Town, Xinmi City, Henan Province, suffered from lumbar disc herniation. She recovered after taking this medicine for 18 days and has not recurred so far.
病例4:殷某,女,家住河南省新密市北环路,患急性腰肌损伤,服用此药7天后痊愈,至今未复发。 Case 4: Yin, female, who lives in Beihuan Road, Xinmi City, Henan Province, suffered from acute psoas muscle injury, recovered after taking this medicine for 7 days, and has not recurred so far.
病例5:陈某,男,家住郑州市亚星小区,患滑膜炎,服用此药15天后痊愈,至今未复发。 Case 5: Chen, male, who lives in Yaxing District, Zhengzhou City, suffered from synovitis. He recovered after taking this medicine for 15 days and has not recurred so far.
药物效果对比: Drug effect comparison:
剂型为口服丸剂,在治疗足底痛方面的药物中,多数采用外用制剂,将采用不同药物治疗的效果进行对比,具体内容如下: The dosage form is oral pills. Most of the medicines for plantar pain use external preparations. The effects of different medicines will be compared. The details are as follows:
将通过服用本发明提供的药物治愈的病例作为试验组,然后再从郑州市新密市其他医院或者诊所选出同类病例作为对照,共260例,作为对照组,统计治疗效果,治疗效果包括平均有效时间和治愈后的反弹率,统计结果如表1所示: The cases cured by taking the medicine provided by the present invention are used as test group, then select similar cases from other hospitals or clinics in Xinmi City, Zhengzhou City as contrast, totally 260 cases, as matched group, statistical treatment effect, treatment effect includes average Effective time and rebound rate after curing, statistical results are shown in Table 1:
表1: Table 1:
由以上可知,本发明补肝肾、强筋骨、除风湿、补气活血、止痛消炎之功效,对腰椎肩盘突出、急性腰损伤、滑膜炎、腰腿疼痛、骨质增生等症治疗效果显著。 From the above, it can be known that the present invention has the effects of nourishing liver and kidney, strengthening muscles and bones, removing rheumatism, invigorating qi and promoting blood circulation, relieving pain and reducing inflammation, and has a therapeutic effect on diseases such as lumbar disc herniation, acute lumbar injury, synovitis, lumbago and leg pain, and bone hyperplasia. significantly.
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| CN1297770A (en) * | 1999-11-30 | 2001-06-06 | 许鸿起 | Meridian passage dredging and pain relieving medicated liquor |
| CN1634497A (en) * | 2004-12-06 | 2005-07-06 | 高振东 | Plaster for relaxing muscles and tendons and eliminating numbness |
| CN1686409A (en) * | 2005-04-19 | 2005-10-26 | 孙继超 | Bone impediment dispersion sticking plaster |
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| CN1297770A (en) * | 1999-11-30 | 2001-06-06 | 许鸿起 | Meridian passage dredging and pain relieving medicated liquor |
| CN1634497A (en) * | 2004-12-06 | 2005-07-06 | 高振东 | Plaster for relaxing muscles and tendons and eliminating numbness |
| CN1686409A (en) * | 2005-04-19 | 2005-10-26 | 孙继超 | Bone impediment dispersion sticking plaster |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2016153365A1 (en) | 2015-03-24 | 2016-09-29 | Yu Gracia Fe | Naturally-derived compositions from calamus ornatus for anti-inflammatory applications |
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