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CN103310685A - Eukaryote chromosome mode structure teaching aid - Google Patents

Eukaryote chromosome mode structure teaching aid Download PDF

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CN103310685A
CN103310685A CN2013102770088A CN201310277008A CN103310685A CN 103310685 A CN103310685 A CN 103310685A CN 2013102770088 A CN2013102770088 A CN 2013102770088A CN 201310277008 A CN201310277008 A CN 201310277008A CN 103310685 A CN103310685 A CN 103310685A
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chromosome
teaching aid
string
pattern structure
box
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CN103310685B (en
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曹广力
贡成良
薛仁宇
郑小坚
朱越雄
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Suzhou University
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Abstract

本发明公开了一种真核细胞染色体模式结构教具,其包括“X”形的盒体,一侧固定连接在所述本体上的盖体,设置在所述盒体内的线状的嵌体。本发明结构简单、能生动形象的表现染色体的模式结构。

Figure 201310277008

The invention discloses a eukaryotic cell chromosome model structure teaching aid, which comprises an "X" shaped box body, a cover body fixedly connected to the body on one side, and a linear inlay arranged in the box body. The invention has a simple structure and can vividly express the model structure of the chromosome.

Figure 201310277008

Description

一种真核细胞染色体模式结构教具A teaching aid for eukaryotic chromosome pattern structure

技术领域 technical field

本发明涉及教学用具领域,尤其涉及一种真核细胞染色体模式结构教具。 The invention relates to the field of teaching aids, in particular to a eukaryotic cell chromosome pattern structure teaching aid.

背景技术 Background technique

真核细胞在有丝分裂时DNA高度螺旋化而呈现特定的形态,此时易被碱性染料着色,称之为常染色体。染色体在复制以后,含有纵向并列的两个染色单体,只有在着丝粒区域仍联在一起。即两条染色单体组成一条染色体。每条染色体由两条染色单体组成,中间狭窄处称为着丝点,又称主缢痕,它将染色体分为短臂(p)和长臂(q)。染色体臂的末端存在着一种叫做端粒的结构,它有保持染色体完整性的功能。 During mitosis, the DNA of eukaryotic cells is highly helicated and presents a specific shape, which is easily stained by basic dyes, called autosomes. After the chromosome is replicated, it contains two chromatids juxtaposed vertically, and only the centromere region is still connected together. That is, two chromatids form a chromosome. Each chromosome consists of two chromatids, and the narrow place in the middle is called the centromere, also known as the main constriction, which divides the chromosome into a short arm (p) and a long arm (q). At the end of chromosome arms there is a structure called telomere, which has the function of maintaining the integrity of chromosomes.

真核染色体含有线性双链DNA,DNA和多种类型的相关蛋白质构成染色体。染色体的超微结构显示染色体是由直径仅10纳米的DNA-组蛋白高度螺旋化的纤维所组成。与核小体结合的组蛋白H1诱导其组装成6个核小体的环,并且这些环组成圆筒状螺线管结构。 Eukaryotic chromosomes contain linear double-stranded DNA, DNA and various types of related proteins that make up chromosomes. The ultrastructure of chromosomes shows that chromosomes are composed of DNA-histone highly helical fibers with a diameter of only 10 nanometers. Binding of histone HI to nucleosomes induces their assembly into rings of 6 nucleosomes, and these rings form cylindrical helical structures.

真核染色体可被不同程度的浓缩。从染色体的一级结构经螺旋化形成中空的线状体,称为螺线体或螺旋管或核丝或螺线筒,这是染色体的“二级结构”,其外径约30纳米,内径10纳米,相邻螺旋间距为11纳米。螺线体再进一步螺旋化,形成直径为0.4微米(μm)的筒状体,称为超螺线体。这就是染色体的“三级结构”。超螺线体进一步折叠盘绕后,形成染色单体—染色体的“四级结构”。 Eukaryotic chromosomes can be condensed to varying degrees. The primary structure of the chromosome is spiralized to form a hollow linear body, called a helix or a helical tube or a nuclear filament or a helicoid, which is the "secondary structure" of the chromosome, with an outer diameter of about 30 nanometers and an inner diameter of 10 nm, and the pitch between adjacent helices is 11 nm. The helicoid is further spiralized to form a cylindrical body with a diameter of 0.4 microns (μm), called a superhelicoid. This is the "tertiary structure" of chromosomes. After the superhelicoid is further folded and coiled, it forms a chromatid—the "quaternary structure" of chromosomes.

在教学领域中,对于染色体的结构教学通常是通过图片形式,但图片形式缺少立体感,也不生动,难以激发学生的兴趣,也不能很好的展现染色体的具体结构特征。 In the field of teaching, the teaching of chromosome structure is usually in the form of pictures, but the picture form lacks three-dimensional sense and is not vivid, it is difficult to stimulate students' interest, and it cannot well show the specific structural characteristics of chromosomes.

发明内容 Contents of the invention

本发明的目的是提供一种结构简单、能够良好展现染色体结构的染色体模式结构教具。 The object of the present invention is to provide a chromosome model structure teaching aid which has a simple structure and can well display the chromosome structure.

为达到上述发明目的,本发明采用的技术方案是:一种真核细胞染色体模式结构教具,其包括“X”形的盒体,一侧固定连接在所述盒体上的盖体,设置在所述盒体内的线状的嵌体。 In order to achieve the purpose of the above invention, the technical solution adopted by the present invention is: a eukaryotic cell chromosome pattern structure teaching aid, which includes an "X" shaped box body, one side of which is fixedly connected to the box body, and is arranged on the A linear inlay in the box.

优选的技术方案,所述盖体与所述盒体通过卡扣开合。 In a preferred technical solution, the cover and the box are opened and closed by buckles.

优选的技术方案,所述嵌体包括螺旋形线状的本体、连接在所述本体一端的端体,所述端体又包括两根连接所述本体的结构线、均匀设置在所述两根结构线间的串条,所述结构线呈螺旋形。 In a preferred technical solution, the inlay includes a helical linear body, an end body connected to one end of the body, and the end body further includes two structural lines connected to the body, uniformly arranged on the two A string of strips between structural lines, said structural lines being in the form of a helix.

进一步技术方案,所述串条上设置有两个串珠。 In a further technical solution, two strings of beads are arranged on the string.

上述技术方案中,螺旋形的本体为软质线,可以受力拉伸;端体的结构线也为软质线,可以受力拉伸。 In the above technical solution, the helical body is a soft wire, which can be stretched under force; the structural wire of the end body is also a soft wire, which can be stretched under force.

染色体的一级结构经螺旋化形成中空的线状体,称为螺线体或核丝或螺线筒或螺旋管,这是染色体的“二级结构”, 螺线体的每一周螺旋包括6个核小体; 螺线体再进一步螺旋化,形成超螺线体,这就是染色体的“三级结构”;超螺线体进一步折叠盘绕后,形成染色单体,染色体的“四级结构”;两条染色单体组成一条染色体。 The primary structure of the chromosome is helicized to form a hollow linear body, which is called the helix or nuclear filament or the helix or the helical tube. This is the "secondary structure" of the chromosome. Each helix of the helix includes 6 A nucleosome; the spirochete is further spiraled to form a superhelix, which is the "tertiary structure" of the chromosome; after the superhelix is further folded and coiled, a chromatid is formed, the "quaternary structure" of the chromosome ; Two chromatids form a chromosome.

 上述技术方案中,所述盒体代表真核细胞的中期染色体,嵌体代表染色单体中的DNA分子,串条代表碱基对,串珠代表碱基,可用不同颜色来表示不同类型的碱基。 In the above technical scheme, the box body represents the metaphase chromosome of the eukaryotic cell, the inlay represents the DNA molecule in the chromatid, the string represents the base pair, and the string of beads represents the base, and different colors can be used to represent different types of bases .

由于上述技术方案运用,本发明与现有技术相比具有下列优点: Due to the use of the above-mentioned technical solutions, the present invention has the following advantages compared with the prior art:

本发明结构简单、使用方便,不仅能具体的展示染色体的结构而且通过三维立体机构加深使用者对于染色体模式结构的记忆。 The invention is simple in structure and easy to use, not only can specifically display the structure of the chromosome but also can deepen the user's memory of the chromosome pattern structure through the three-dimensional mechanism.

附图说明 Description of drawings

图1为本发明示意图; Fig. 1 is a schematic diagram of the present invention;

图2为本发明的拆分图。 Figure 2 is an exploded view of the present invention.

其中:1、盒体;2、盖体;3、嵌体;4、本体;5、串条;6、串珠;7、端体;8、结构线。 Among them: 1. Box body; 2. Cover body; 3. Inlay; 4. Body; 5. String string; 6. Bead string; 7. End body; 8. Structure line.

具体实施方式 Detailed ways

下面结合附图及实施例对本发明作进一步描述: The present invention will be further described below in conjunction with accompanying drawing and embodiment:

实施例一: Embodiment one:

如图1、2所示,一种染色体模式结构教具,其包括“X”形的盒体1,一侧固定连接在盒体1上的盖体2,设置在盒体2内的线状的嵌体3。 As shown in Figures 1 and 2, a chromosome pattern structure teaching aid includes an "X"-shaped box body 1, a cover body 2 fixedly connected to the box body 1 on one side, and a linear Inlay 3.

盖体2与盒体1通过卡扣开合。 The cover body 2 and the box body 1 are opened and closed by buckles.

嵌体3包括螺旋形线状的本体4、连接在本体4一端的端体7,端体7又包括两根连接本体4的结构线8、均匀设置在两根结构线8间的串条5,结构线8呈螺旋形。 The inlay 3 includes a helical body 4, an end body 7 connected to one end of the body 4, and the end body 7 further includes two structural lines 8 connected to the main body 4, and string bars 5 evenly arranged between the two structural lines 8. , the structural line 8 is helical.

串条5上设置有两个串珠6。 Two strings of beads 6 are arranged on the string 5 .

串珠6可以制成红、蓝、黄、绿4种不同的颜色,各代表染色体中的4种碱基A、T、C、G,其中A与T配对、C与G配对,即红色、蓝色串珠6在一条串条5上,黄色、绿色串珠6在一条串条5上。 Beads 6 can be made into 4 different colors of red, blue, yellow and green, each representing the 4 bases A, T, C, and G in the chromosome, where A is paired with T, and C is paired with G, that is, red, blue Color beads 6 are on a string 5, and yellow and green beads 6 are on a string 5.

盒体1代表染色体,盒体1为“X”形,从中间分为左右两部分,其中左半部及右半部各代表一条染色体单体,左半部与右半部中间连接处代表染色体上的着丝粒,嵌体3代表染色单体中的DNA分子,串条5代表碱基对。 Box 1 represents the chromosome. Box 1 is "X" shaped and is divided into left and right parts from the middle. The left half and the right half represent a chromosome monomer, and the junction between the left half and the right half represents the chromosome. On the centromere, inlay 3 represents the DNA molecule in the chromatid, and string 5 represents the base pair.

本实施例结构简单,能生动形象的表现染色体的结构特征。 This embodiment has a simple structure and can vividly express the structural features of chromosomes.

Claims (4)

1.一种真核细胞染色体模式结构教具,其特征在于:其包括“X”形的盒体,一侧固定连接在所述盒体上的盖体,设置在所述盒体内的线状的嵌体。 1. A teaching aid for eukaryotic chromosome pattern structure, characterized in that: it comprises an "X" shaped box, one side is fixedly connected to the lid on the box, and the linear Inlay. 2.根据权利要求1所述的一种染色体模式结构教具,其特征在于:所述盖体与所述盒体通过卡扣开合。 2. A chromosome pattern structure teaching aid according to claim 1, characterized in that: the cover and the box are opened and closed by buckles. 3.根据权利要求1所述的一种真核细胞染色体模式结构教具,其特征在于:所述嵌体包括螺旋形线状的本体、连接在所述本体一端的端体,所述端体又包括两根连接所述本体的结构线、均匀设置在所述两根结构线间的串条,所述结构线呈螺旋形。 3. A eukaryotic cell chromosome pattern structure teaching aid according to claim 1, characterized in that: said inlay comprises a helical linear body, a terminal body connected to one end of said body, and said terminal body is It includes two structural lines connecting the body, and string bars evenly arranged between the two structural lines, and the structural lines are in a spiral shape. 4.根据权利要求3所述的一种真核细胞染色体模式结构教具,其特征在于:所述串条上设置有两个串珠。 4. A eukaryotic cell chromosome pattern structure teaching aid according to claim 3, characterized in that: two beads are arranged on the string.
CN201310277008.8A 2013-07-03 2013-07-03 Eukaryote chromosome mode structure teaching aid Expired - Fee Related CN103310685B (en)

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