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CN102603915A - Method for extracting oat beta-glucan - Google Patents

Method for extracting oat beta-glucan Download PDF

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Publication number
CN102603915A
CN102603915A CN2012100642625A CN201210064262A CN102603915A CN 102603915 A CN102603915 A CN 102603915A CN 2012100642625 A CN2012100642625 A CN 2012100642625A CN 201210064262 A CN201210064262 A CN 201210064262A CN 102603915 A CN102603915 A CN 102603915A
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CN
China
Prior art keywords
oat bran
glucan
temperature
beta
avenabeta glucosan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2012100642625A
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Chinese (zh)
Inventor
郁磊
陶丁伟
邹联
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Wuxi Deguan Biotechnology Co Ltd
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Wuxi Deguan Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wuxi Deguan Biotechnology Co Ltd filed Critical Wuxi Deguan Biotechnology Co Ltd
Priority to CN2012100642625A priority Critical patent/CN102603915A/en
Publication of CN102603915A publication Critical patent/CN102603915A/en
Pending legal-status Critical Current

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  • Medicines Containing Plant Substances (AREA)

Abstract

A method for extracting oat beta-glucan belongs to the technical field of plant extracts. The method includes the steps: firstly, mixing crushed oat bran with water to adjust PH (potential of hydrogen) to range from 6 to 7; secondly, adding high-temperature alpha-amylase to hydrolyze starch in oat bran at the temperature of 85-90 DEG C; thirdly, adding glucoamylase for treatment at the temperature of 55-60 DEG C and filtering to obtain supernatant liquid; fourthly, using an ultrafiltration membrane with molecular cutoff being 50000Da to 100000Da for filtering to obtain beta-glucan solution; and fifthly, spraying and drying to obtain beta-glucan product. The method for extracting oat beta-glucan is high in feeding rate, free of organic reagent, simple and convenient, the extraction rate is up to 85%, the beta-glucan product purity is high and is more than 80%, and product solubility is greatly improved.

Description

A kind of method of extracting avenabeta glucosan
Technical field
A kind of method of extracting avenabeta glucosan of the present invention belongs to the plant milk extract technical field.
Background technology
Oat beta-glucan is by extracting in the oat bran, extracting the back added value of product and heighten.Oat beta-glucan is with β-1,3-, and β-1, the viscosity poly VISOSE that the 4-glycosidic link couples together, it mainly concentrates on the aleurone layer of oat bran.Oat beta-glucan has multiple function, can reduce fat, controlling blood sugar, strengthening immunity, and anti-ly treat constipation, improve intestinal microenvironment etc., be widely used in medicine and field of health care food.
Summary of the invention
The purpose of this invention is to provide a kind of process for extracting of new enzyme process oat beta-glucan, this method can solve the insoluble problem of existing oat beta-glucan finished product, and with an organic solvent, service temperature is high, the deficiency of aspects such as not energy-conserving and environment-protective.
The technical scheme that the present invention adopts: a kind of method of extracting avenabeta glucosan comprises the steps:
(1) oat bran is ground into 60-100 purpose oat bran powder.The oat bran powder is joined in the deionized water of 9-10 times of quality, regulating the pH value is 6-7.
(2) add high-temperature at the 85-90 ℃ of starch of handling down in the hydrolysis oat bran powder; The unit of activity of said high-temperature is 90KNU/g; Consumption is 0.4-0.6g high-temperature/100g oat bran, and the treatment time is 10-15 minute, and postcooling is to 55-60 ℃.
(3) add glucoamylase and handle down at 55-60 ℃, pH 4.0-4.5, filtration obtains clarified liq, and the unit of activity 390ASPU/g of said glucoamylase, 260GAU/g, consumption are 0.8-1.0g glucoamylase/100g oat bran; Treatment time is 1-2 hour.
(4) with separating the filtrating that obtains in the step (3), adopting molecular weight cut-off is the ultrafiltration membrance filter of 50000Da-100000Da, collects trapped fluid, obtains the avenabeta glucosan liquid concentrator.
(5) step (4) gained avenabeta glucosan liquid concentrator jet drying is obtained the avenabeta glucosan product.
Plate Filtration is adopted in filtration in the step (3).
Also be added with perlite in the Plate Filtration as flocculating aids.
The high-temperature that the present invention adopts is a kind of temperature of reaction the highest enzyme of activity in the time of 85-90 ℃, is characterized in reducing viscosity of sludge fast, improves the rate that feeds intake.Its advantage is to save the energy, and can deactivation in subsequent technique.
The glucoamylase that the present invention adopts, the quick circumscribed starch 1 of ability, 4-1,6 glycosidic links make starch be converted into glucose to greatest extent, and its advantage is that high concentration substrate is under the condition that high enzyme is lived, and hydrolysis rate is the fastest.
Be under the condition of 4.0-4.5 in the pH value in the step of the present invention (3), remove albumen, principle is that the albumen in the wheat bran is separated out when using iso-electric point, leaves standstill the back and removes through Plate Filtration.
The used raw material of the present invention except that specifying, all commercially available getting.
Beneficial effect of the present invention is following: in the production technique of the present invention, the one feeding rate is big, and the rate of utilization of equipment is high, and not with an organic solvent, energy-conserving and environment-protective, safe.
Embodiment
Further specify the present invention with embodiment below, but the present invention is not limited.The experimental technique of unreceipted actual conditions in the following example, usually according to normal condition, or the condition of advising according to manufacturer.Described per-cent is meant mass percent if there is not special instruction.High-temperature of the present invention is available from the Liquozyme Supra of Novozymes Company type, enzyme activity 90KNU/g.Glucoamylase available from outstanding can the Optimax4060 of company of section type, enzyme activity 390ASPU/g, 260GAU/g, the method for other adjust pH of the present invention is the technological method that present technique field personnel use always, promptly adds acid (example hydrochloric acid) acid adjustment property, adds alkali (like NaOH) and transfers alkalescence.
Embodiment 1
A kind of process for extracting of avenabeta glucosan comprises the steps:
One, the 100kg oat bran is ground into 60-100 purpose oat bran powder.
Two, the oat bran powder is joined in the 900kg deionized water, regulating the pH value is 6.0, adds high-temperature 600g; Be warming up to 10 minutes postcooling to 60 of 85 ℃ of stir process ℃.
Three, adjust pH 4.5, add glucoamylase 800g, and under 60 ℃, Plate Filtration is collected filtrating stir process leaves standstill 10min after 1.5 hours after.
Four, be the ultrafiltration membrance filter of 50000Da-100000Da with separating the filtrating that obtains in the step 3 by adopting molecular weight cut-off, collecting molecular weight is the trapped fluid of 50000Da-100000Da, is concentrated into 1/3rd of original volume and obtains the avenabeta glucosan liquid concentrator.
Five, step 4 gained avenabeta glucosan liquid concentrator jet drying is obtained the about 10.5kg of avenabeta glucosan finished product, recording glucan content through AOAC 995.16 methods is 85.5%.
Embodiment 2
A kind of process for extracting of avenabeta glucosan comprises the steps:
One, the 500kg oat bran is ground into 60-100 purpose oat bran powder.
Two, the oat bran powder is joined in the 5000kg deionized water, regulating the pH value is 6.5, adds high-temperature 2Kg; Be warming up to 15 minutes postcooling to 60 of 90 ℃ of stir process ℃.
Three, adjust pH 4.0, add glucoamylase 5kg, and under 55 ℃, Plate Filtration is collected filtrating stir process leaves standstill 10min after 2 hours after.
Four, be the ultrafiltration membrance filter of 50000Da-100000Da with separating the filtrating that obtains in the step 3 by adopting molecular weight cut-off, collecting molecular weight is the trapped fluid of 50000Da-100000Da, is concentrated into 1/3rd of original volume and obtains the avenabeta glucosan liquid concentrator.
Five, step 4 gained avenabeta glucosan liquid concentrator jet drying is obtained the about 55kg of avenabeta glucosan finished product, recording glucan content through AOAC 995.16 methods is 83.8%.

Claims (3)

1. method of extracting avenabeta glucosan is characterized in that step is following:
(1) add deionized water and stirring after oat bran was pulverized the 60-100 mesh sieve, the weight ratio of oat bran powder and deionized water is 1: 9-10, regulate pH 6-7;
(2) add high-temperature at the 85-90 ℃ of starch of handling down in the hydrolysis oat bran powder; The unit of activity of said high-temperature is 90KNU/g; Consumption is 0.4-0.6g high-temperature/100g oat bran, and the treatment time is 10-15 minute, and postcooling is to 55-60 ℃;
(3) add glucoamylase and handle down at 55-60 ℃, pH 4.0-4.5, filtration obtains clarified liq, and the unit of activity 390ASPU/g of said glucoamylase, 260GAU/g, consumption are 0.8-1.0g glucoamylase/100g oat bran; Treatment time is 1-2 hour;
(4) with separating the filtrating that obtains in the step (3), adopting molecular weight cut-off is the ultrafiltration membrance filter of 50000Da-100000Da, collects trapped fluid, obtains the avenabeta glucosan liquid concentrator;
(5) step (4) gained avenabeta glucosan liquid concentrator jet drying is obtained the avenabeta glucosan product.
2. method according to claim 1 is characterized in that: Plate Filtration is adopted in the filtration in the step (3).
3. method according to claim 2 is characterized in that: also be added with perlite in the Plate Filtration as flocculating aids.
CN2012100642625A 2012-03-13 2012-03-13 Method for extracting oat beta-glucan Pending CN102603915A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2012100642625A CN102603915A (en) 2012-03-13 2012-03-13 Method for extracting oat beta-glucan

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Application Number Priority Date Filing Date Title
CN2012100642625A CN102603915A (en) 2012-03-13 2012-03-13 Method for extracting oat beta-glucan

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CN102603915A true CN102603915A (en) 2012-07-25

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102911287A (en) * 2012-11-21 2013-02-06 福建科宏生物工程有限公司 Method for preparing bamboo leaf polysaccharides from bamboo pulp
CN103204952A (en) * 2013-03-18 2013-07-17 南通博硕生物工程有限公司 Oat glucan extraction method
CN103772527A (en) * 2014-02-24 2014-05-07 常州毅博生物科技有限公司 Method for extracting high-purity beta-glucosan from oat bran
CN104448028A (en) * 2014-11-27 2015-03-25 广东省食品工业研究所 Method for recycling ethyl alcohol in oat beta-glucan and obtaining dried and sterile oat beta-glucan by gradually warming rising temperature
CN104780784A (en) * 2012-08-14 2015-07-15 雅培制药有限公司 Powdered nutritional composition comprising dryblended neat cereal beta-glucan and resistant starch
CN109400751A (en) * 2019-01-07 2019-03-01 张家口康生物科技有限公司 A kind of low content oat beta-glucan extracting method
CN113332175A (en) * 2021-06-04 2021-09-03 吉林省国大生物工程有限公司 Medical wet repairing plaster

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Publication number Priority date Publication date Assignee Title
CN1869077A (en) * 2006-06-29 2006-11-29 北京工商大学 Method of extracting avenabeta glucosan
CN1901810A (en) * 2003-11-24 2007-01-24 毕奥维勒普国际有限公司 Soluble dietary fibre from oat and barley grains, method for producing a fraction rich in beta-glucan and use of the fraction in foods, pharmaceuticals and cosmetics
CN1966531A (en) * 2006-11-08 2007-05-23 江南大学 Process for preparing oat beta-glucans
CN101857646A (en) * 2010-05-27 2010-10-13 山西金绿禾燕麦研究所 Method for extracting high-purity beta-glucan and whole oat flour from oat bran
CN102002115A (en) * 2010-10-09 2011-04-06 广东省食品工业研究所 Method for primarily separating components of oat bran

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CN1901810A (en) * 2003-11-24 2007-01-24 毕奥维勒普国际有限公司 Soluble dietary fibre from oat and barley grains, method for producing a fraction rich in beta-glucan and use of the fraction in foods, pharmaceuticals and cosmetics
CN1869077A (en) * 2006-06-29 2006-11-29 北京工商大学 Method of extracting avenabeta glucosan
CN1966531A (en) * 2006-11-08 2007-05-23 江南大学 Process for preparing oat beta-glucans
CN101857646A (en) * 2010-05-27 2010-10-13 山西金绿禾燕麦研究所 Method for extracting high-purity beta-glucan and whole oat flour from oat bran
CN102002115A (en) * 2010-10-09 2011-04-06 广东省食品工业研究所 Method for primarily separating components of oat bran

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104780784A (en) * 2012-08-14 2015-07-15 雅培制药有限公司 Powdered nutritional composition comprising dryblended neat cereal beta-glucan and resistant starch
CN102911287A (en) * 2012-11-21 2013-02-06 福建科宏生物工程有限公司 Method for preparing bamboo leaf polysaccharides from bamboo pulp
CN103204952A (en) * 2013-03-18 2013-07-17 南通博硕生物工程有限公司 Oat glucan extraction method
CN103772527A (en) * 2014-02-24 2014-05-07 常州毅博生物科技有限公司 Method for extracting high-purity beta-glucosan from oat bran
CN104448028A (en) * 2014-11-27 2015-03-25 广东省食品工业研究所 Method for recycling ethyl alcohol in oat beta-glucan and obtaining dried and sterile oat beta-glucan by gradually warming rising temperature
CN109400751A (en) * 2019-01-07 2019-03-01 张家口康生物科技有限公司 A kind of low content oat beta-glucan extracting method
CN113332175A (en) * 2021-06-04 2021-09-03 吉林省国大生物工程有限公司 Medical wet repairing plaster

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Application publication date: 20120725