CN1025590C - preparation method of anal fistula injection - Google Patents
preparation method of anal fistula injection Download PDFInfo
- Publication number
- CN1025590C CN1025590C CN 90105504 CN90105504A CN1025590C CN 1025590 C CN1025590 C CN 1025590C CN 90105504 CN90105504 CN 90105504 CN 90105504 A CN90105504 A CN 90105504A CN 1025590 C CN1025590 C CN 1025590C
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- Prior art keywords
- gram
- preparation
- injection
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- Expired - Fee Related
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- 238000002360 preparation method Methods 0.000 title claims abstract description 11
- 208000004680 Rectal Fistula Diseases 0.000 title claims abstract description 10
- 206010002156 anal fistula Diseases 0.000 title claims abstract description 10
- 238000002347 injection Methods 0.000 title claims abstract description 7
- 239000007924 injection Substances 0.000 title claims abstract description 7
- 239000003814 drug Substances 0.000 claims abstract description 7
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims abstract description 6
- 230000001954 sterilising effect Effects 0.000 claims abstract description 6
- 238000001914 filtration Methods 0.000 claims abstract description 5
- 239000007788 liquid Substances 0.000 claims abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 5
- 229910052799 carbon Inorganic materials 0.000 claims abstract description 4
- 238000001816 cooling Methods 0.000 claims abstract description 4
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims abstract 2
- 229920000053 polysorbate 80 Polymers 0.000 claims abstract 2
- 201000007772 internal hemorrhoid Diseases 0.000 claims description 7
- 239000009636 Huang Qi Substances 0.000 claims description 5
- 241000283956 Manis Species 0.000 claims description 5
- 238000004659 sterilization and disinfection Methods 0.000 claims description 5
- 206010062717 Increased upper airway secretion Diseases 0.000 claims description 4
- 208000026435 phlegm Diseases 0.000 claims description 4
- 238000001556 precipitation Methods 0.000 claims description 2
- 239000002994 raw material Substances 0.000 claims 2
- 239000008215 water for injection Substances 0.000 abstract description 3
- 238000009835 boiling Methods 0.000 abstract 3
- 238000004806 packaging method and process Methods 0.000 abstract 2
- 241001061264 Astragalus Species 0.000 abstract 1
- 241000931143 Gleditsia sinensis Species 0.000 abstract 1
- 241000283966 Pholidota <mammal> Species 0.000 abstract 1
- 241001671204 Stemona Species 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 abstract 1
- 230000001376 precipitating effect Effects 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 238000007789 sealing Methods 0.000 abstract 1
- 210000004233 talus Anatomy 0.000 abstract 1
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 238000000034 method Methods 0.000 description 4
- 241000258920 Chilopoda Species 0.000 description 3
- 235000019445 benzyl alcohol Nutrition 0.000 description 2
- 229920000136 polysorbate Polymers 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 238000010792 warming Methods 0.000 description 2
- 206010002176 Anal stenosis Diseases 0.000 description 1
- 206010021639 Incontinence Diseases 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000003610 charcoal Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention belongs to a preparation method of anal fistula injection. Is prepared by 20 to 25 percent of Chinese honeylocust spine, 10 to 15 percent of pangolin scales, 10 to 15 percent of astragalus, 5 to 10 percent of rhizoma coptidis from Sichuan of China, 7 to 12 percent of stemona and the like, and liquid medicine is obtained by boiling, refluxing, boiling at constant temperature, distilling, adding active carbon for boiling, cooling and filtering, precipitating, filtering again and the like; adding tween-80 and benzyl alcohol, adjusting pH, adding water for injection, sterilizing with steam at high temperature, packaging, sealing, and packaging.
Description
The invention belongs to a kind of preparation method of injection for anal fistula.
Anal fistula disease and each phase internal hemorrhoid disease are a kind of common stubborn diseases, are difficult for radical cure; According to traditional Therapeutic Method, be to adopt operative drainage and seton treatment method, but still can cause the adverse consequences of anal stenosis and anal incontinence accidentally.
The objective of the invention is to bring benefit to the people in order to reduce anal fistula disease and each phase internal hemorrhoid patient's misery.
The present invention adopts Chinese medicine Spina Gleditsiae, Squama Manis, Rhizoma Coptidis, the Radix Astragali, the preparations such as (parches) of centipede worm, and employing is boiled, and methods such as backflow is boiled, distillation, charcoal treatment are prepared from, and are to be used for the treatment of anal fistula and each phase internal hemorrhoid disease.
The method of the present invention's preparation is to adopt Chinese medicine Spina Gleditsiae 20% to 25%, Squama Manis 10% to 15%, add and be placed with in the alembic of 50 to 100 premium on currency, be warming up to 70～90 degree, constant temperature is 20 to 40 minutes then, cooling, add the Radix Astragali 10% to 15% again, Rhizoma Coptidis 5% to 10%, centipede worm (parch) 7% to 12% continues to heat to 80～110 degree, backflow constant temperature 20 to 30 minutes, collect fraction then, receive behind the former medicine, add 0.1% to 0.5% active carbon and reduce phlegm and internal heat former and decolouring was boiled 10 to 30 minutes, carry out cold filtration, precipitation refilters, and then the gained medicinal liquid is added tween 80,0.5% to 1%, benzyl alcohol makes molten, and regulating pH value is 7 to 9, adds to the full amount of water for injection, sterilization is 20 to 40 minutes under 100 to 150 degree steams, carries out fill then, seal, be packaged into box.Technology sees accompanying drawing for details.
The injection that the method for the present invention's preparation is made is to be used for sick and each the phase internal hemorrhoid patient of anal fistula, and each only need of anal fistula patient annotated 1 to 5 milliliter, and general internal hemorrhoid patient only need annotate 0.2 to 0.4 milliliter, and especially big internal hemorrhoid patient infusion is no more than 1 milliliter.
Embodiment:
1. required medicine is differentiated that foreign material are removed in washing, shred standby.
2. the Spina Gleditsiae of getting ready being taken by weighing 100 to 150 grams, Squama Manis 80 to 120 gram adds and is placed with in the alembic of 50～100 premium on currency, be warming up to 80～100 degree, constant temperature 20 to 40 minutes, cooling, add the Radix Astragali 80 to 120 grams, Rhizoma Coptidis 30 to 80 grams, centipede worm (parch) 50 to 90 grams continue to heat up and boil to 80～120 degree, backflow constant temperature 20 to 40 minutes is collected fraction then.
3. receive behind the former medicine, the active carbon of adding 0.1%～0.5% reduces phlegm and internal heat former and decolouring was boiled 10 to 30 minutes, cold filtration precipitates, refilters, and medicinal liquid is added tween 80,0.5%～1%, benzyl alcohol makes molten, and regulating pH value is 7 to 9, adds water for injection to full dose, sterilization is 20 to 40 minutes under 100～150 degree steam, carries out fill then, seals, is packaged into box.
Claims (3)
1, a kind of preparation method that is used for the treatment of the injection of anal fistula and each phase internal hemorrhoid, it is characterized in that: adopt the Chinese medicine preparation, raw material weight is: Spina Gleditsiae 100-150 gram, Squama Manis 80-120 gram, Rhizoma Coptidis 30-80 gram, Prospirolboli joannsi (parch) 50-90 gram, Radix Astragali 80-120 gram, raw material add water boil, distill, add active carbon reduces phlegm and internal heat former and decolouring, boils, cold filtration then, precipitation refilters, in the gained medicinal liquid, add the tween 80 that accounts for medicinal liquid total amount 0.5-1%, the re-adjustment pH value is 7-9, adding distil water is to full dose, sterilization, canned, seal, be packaged into box.
2, the preparation method of injection as claimed in claim 1, it is characterized in that: earlier Spina Gleditsiae and Squama Manis are put into alembic and be warmed up to 80-100 ℃, constant temperature 20-40 minute, the cooling back adds Rhizoma Coptidis, the Radix Astragali, Prospirolboli joannsi (parch) is warmed up to 80-120 ℃, and backflow constant temperature 20-40 minute is collected fraction then.
3, as claim 1,2 described preparation methoies, it is characterized in that: the medical activated carbon of gained fraction adding 0.1-0.5% reduces phlegm and internal heat former and decolours, boiled 10-30 minute; 100-150 ℃ steam sterilization 20-40 minute adopted in sterilization.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 90105504 CN1025590C (en) | 1990-07-20 | 1990-07-20 | preparation method of anal fistula injection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 90105504 CN1025590C (en) | 1990-07-20 | 1990-07-20 | preparation method of anal fistula injection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1047806A CN1047806A (en) | 1990-12-19 |
| CN1025590C true CN1025590C (en) | 1994-08-10 |
Family
ID=4879318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 90105504 Expired - Fee Related CN1025590C (en) | 1990-07-20 | 1990-07-20 | preparation method of anal fistula injection |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1025590C (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101780074B1 (en) | 2008-12-15 | 2017-09-19 | 에코팜, 엘엘씨 | Treating idiopathic thrombocytopenic purpura with compositions comprising extracts of astragalus membranaceus |
-
1990
- 1990-07-20 CN CN 90105504 patent/CN1025590C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1047806A (en) | 1990-12-19 |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |