CN101143155A - A kind of double ginseng composition and its application - Google Patents
A kind of double ginseng composition and its application Download PDFInfo
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- CN101143155A CN101143155A CNA2006100477641A CN200610047764A CN101143155A CN 101143155 A CN101143155 A CN 101143155A CN A2006100477641 A CNA2006100477641 A CN A2006100477641A CN 200610047764 A CN200610047764 A CN 200610047764A CN 101143155 A CN101143155 A CN 101143155A
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- ginseng
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- stichopus japonicus
- triplostegiae grandiflorae
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Abstract
本发明涉及海参与人参，具体地说是一种双参组合物：由海参和人参组成，海参和人参的重量比为0.1～10∶0.1～10。本发明通过合理的调配海参与人参(以下简称双参)，使双参功效互补，同时又避免了单独使用易产生阴阳失衡的问题；可以双参冻干粉或提取物为基础，开发双参化妆品、保健品和医药等系列产品。The invention relates to sea cucumber and ginseng, in particular to a double ginseng composition: it consists of sea cucumber and ginseng, and the weight ratio of sea cucumber and ginseng is 0.1-10:0.1-10. In the present invention, through the rational deployment of sea cucumber and ginseng (hereinafter referred to as double ginseng), the effects of the two ginseng are complementary, and at the same time, the problem of yin and yang imbalance that is easy to occur when used alone is avoided; the double ginseng can be developed based on the freeze-dried powder or extract of the double ginseng Cosmetics, health care products and pharmaceuticals and other products.
Description
Technical field
The present invention relates to Stichopus japonicus and Radix Ginseng, specifically be exactly by modernized processing technique, Stichopus japonicus and Radix Ginseng or corresponding active component are carried out reasonable compatibility, and exploitation Stichopus japonicus and Radix Ginseng (hereinafter to be referred as Radix Triplostegiae Grandiflorae) compound recipe series of products comprise food, health product, cosmetics and medicine.
Background technology
Stichopus japonicus is not only the delicious food on the dining table, but also is tonic food, and health invigorating, prevent disease, inhibition tumor, life lengthening are all had favorable effects.The traditional Chinese medical science thinks that Stichopus japonicus goes into the heart, kidney, spleen, lung 4 warps, and therefore, the effect of tonification health is very strong.Have the effect that the kidney invigorating, YIN nourishing, tonifying YANG, benefit are smart, nourish blood, moisturize, be applicable to that the caused sexual impotence of suffering from a deficiency of the kidney, premature ejaculation, seminal emission, urine are frequently many; Various losing blood and the anemia that causes; The control of diseases such as pulmonary tuberculosis, neurasthenia, dryness of the intestine constipation, traumatic hemorrhage, edema.The regeneration capacity of Stichopus japonicus is very strong, and Stichopus japonicus is divided into several sections, and every section all can grow up to Stichopus japonicus separately, so Stichopus japonicus has the effect of nourishing, granulation promoting, repair tissue.Therefore, Stichopus japonicus also can be used for wound, skin infection, and the effect of hemostasis, granulation promoting is arranged.In recent years, find that also Stichopus japonicus has the effect of anticancer antibiotic, but anticancer increases and transfer, is cancer patient's good tonic and medicine.
By modern science and technology the Stichopus japonicus active component has been carried out extensive and deep research, fibre composition and Dan Baijutang such as glue unit in the filling of discovery Stichopus japonicus iuntercellular, and extracellular matrix, protein is up to 90% in the while dry Stichopus japonicus, it is 4% that lipid accounts for, about saccharide 6%, other contains a small amount of nucleic acid, and contains calcium, magnesium salt and ferrum, manganese, zinc, copper, molybdenum, selenium and other trace elements.Numerous active substances has been proved in many-sides such as cardiovascular, tumor, defying age, resisting fatigue, anti-inflammatories and has had high activity in the Stichopus japonicus.
Radix Ginseng is one of China's special product valuable ingredient of Chinese medicine, and ancient medicine is learned and begun in the books to see Shennong's Herbal, classifies as top grade.Before more than 2,000 years, people just find gradually that Radix Ginseng has that strongly invigorating primordial QI, peaceful body Fructus Alpiniae Oxyphyllae, supplementing QI for promoting the production of body fluid, tonify deficiency are set upright, the effect of life lengthening, is described as " QI invigorating key medicine ".Modern medicine also proves, Radix Ginseng is except the energy nourishing and fit keeping function, preventing tumor, defying age, arrhythmia, inhibition apoptosis, hypoglycemic, improve learning and memory, sexual function improving and immunologic function and aspect such as relieve the effect of alcohol all effective in cure, so Radix Ginseng more and more is subjected to people's favor in recent years.The main component that comprises in the Radix Ginseng has ginsenoside, ginseng polysaccharide (GPS), panaxynol, volatile oil, low molecular peptide, aminoacid, vitamin, organic acid and various trace elements.Radix Ginseng is the first-selection that people nourish, and still, ginseng is different, and property is different.Therefore, take Radix Ginseng and will distinguish body constitution.The person of having a delicate constitution, chronic disease patients such as hypertension, diabetes, cancer, hepatitis, nephritis should select Radix Ginseng for use.The Radix Ginseng slightly cool in nature, sweet in the mouth, the effect of boosting qi and nourishing yin is arranged, promoting the production of body fluid.Deficiency-cold syndrome it, YANG QI deficiency, winter fear of cold, extremity cold, old man's senilism, women's endocrine disorder person should select Radix Ginseng Rubra for use.Radix Ginseng Rubra is warm in nature, sweet in the mouth, and fragrance is denseer.Severe cardiovascular disease, postoperative extremely feeble, critically ill patient should select wild ginseng for use.
Stichopus japonicus and Radix Ginseng effect are remarkable, but for various reasons, its application has very strong limitation.Existence as holothurians autoenzyme, make that preservation and the processing of Stichopus japonicus are to hamper Stichopus japonicus as the popularization of food between masses always, Radix Ginseng has edible inconvenient puzzlement too, Radix Triplostegiae Grandiflorae component complexity in addition, the directly edible imbalance of YIN and YANG that is easy to cause human body, " the getting angry " that just is commonly called as.
Summary of the invention
Along with the development of modern biotechnology and technological process, can have and understand in depth the activity of Stichopus japonicus and Radix Ginseng, the purpose of this invention is to provide a kind of double ginseng composition and application thereof based on Stichopus japonicus and ginseng composite compatible series; The applicant can according to specific objective selectable with the active component compatibility in the Radix Triplostegiae Grandiflorae, both avoided traditional method to bring the risk of imbalance of YIN and YANG, can shoot the arrow at the target again, improve the utilization rate of Radix Triplostegiae Grandiflorae.
For achieving the above object, the technical solution used in the present invention is:
The present invention with function ingredients and function ingredients, is modulated into the Radix Triplostegiae Grandiflorae compound recipe function ingredients with given efficacy according to the crude product respective attributes; A kind of double ginseng composition is made up of Stichopus japonicus and Radix Ginseng, and the weight ratio of Stichopus japonicus and Radix Ginseng is 0.1～10: 0.1～10.
Described Stichopus japonicus and Radix Ginseng are Stichopus japonicus and ginseng freeze-dried powder;
Preparation process is: 1) with fresh Stichopus japonicus and Radix Ginseng by freezing system dry powder technique, be processed into lyophilized Stichopus japonicus powder and ginseng freeze-dried powder respectively;
2) lyophilized Stichopus japonicus powder and ginseng freeze-dried powder are carried out compatibility according to the doses ratio, can introduce other adjuvants, be modulated into Radix Triplostegiae Grandiflorae dry powder as needs.
On processing technique bases such as Traditional health care product, cosmetics, introduce Radix Triplostegiae Grandiflorae compound recipe function ingredients, Radix Triplostegiae Grandiflorae functional health care product, cosmetics that preparation has specific function, described compositions can make an addition in health product, food or the medicine, and wherein the weight content of double ginseng composition can account for 0.03～30% of product population.
Described health product material can be Mel, Fructus Jujubae and/or Fructus Lycii;
Food material can be Radix Triplostegiae Grandiflorae pulp, Radix Triplostegiae Grandiflorae malted milk and Radix Triplostegiae Grandiflorae cookies; On the basis that conventional beverage, cake or electuary are made, add the Radix Triplostegiae Grandiflorae dry powder that modulates, be made into Radix Triplostegiae Grandiflorae beverage, Radix Triplostegiae Grandiflorae cake or Radix Triplostegiae Grandiflorae electuary.
Medicine can be Radix Triplostegiae Grandiflorae polysaccharide (or oligosaccharide) sheet, Saponin polypeptide capsule.
Based on the Radix Triplostegiae Grandiflorae function ingredients,, obtain the pure product of serial Radix Triplostegiae Grandiflorae active substance by further component segmentation;
Described compositions can make an addition in the cosmetics, when being used for cosmetics, its material that adopts is collagen in the Stichopus japonicus dry powder that extracts according to a conventional method and the volatile oil in the Radix Ginseng, and collagen content accounts for total amount mass ratio 0.5～2.5%, and ginseng essential oil accounts for gross mass 0.3～1%.
A kind of Stichopus japonicus and ginseng composite compatible series product by freezing system Dry technique, are major ingredient with Stichopus japonicus and Radix Ginseng, carry out the production of cosmetics, health product, food and medicine;
Be specially,, Stichopus japonicus and Radix Ginseng be converted into the bioactive dry powder of maintenance, by direct compatibility processing Radix Triplostegiae Grandiflorae food by freezing system Dry technique; Based on dry powder, the active component of Radix Triplostegiae Grandiflorae is extracted and collocation selectively preparation Radix Triplostegiae Grandiflorae active component health product, cosmetics; Based on the Radix Triplostegiae Grandiflorae active component, carry out drug screening, obtain the Radix Triplostegiae Grandiflorae preparation.Pure product are according to certain pharmacologically active compatibility, and the corresponding pharmacological evaluation of process, exploitation Radix Triplostegiae Grandiflorae pharmaceutical preparation.
Specific operation process is:
1) with fresh Stichopus japonicus and Radix Ginseng by freezing system dry powder technique, be processed into lyophilized Stichopus japonicus powder and ginseng freeze-dried powder respectively;
2) with lyophilized Stichopus japonicus powder and ginseng freeze-dried powder in 0.1～10: 0.1～10 ratio is carried out compatibility, introduces other adjuvants, as Fructus Jujubae, Fructus Lycii etc. (Radix Triplostegiae Grandiflorae content account for total amount 0.03～30%), is modulated into Radix Triplostegiae Grandiflorae dry powder;
3) on the basis that conventional beverage, cake or electuary are made, add the Radix Triplostegiae Grandiflorae dry powder that modulates, be made into Radix Triplostegiae Grandiflorae beverage, Radix Triplostegiae Grandiflorae cake or Radix Triplostegiae Grandiflorae electuary.
4) be raw material with the Radix Triplostegiae Grandiflorae lyophilized powder, carry out the segmentation of Radix Triplostegiae Grandiflorae component, comprise water-phase extract, organic facies extract or supercritical extraction product etc.;
5) according to the crude product respective attributes, with Stichopus japonicus function ingredients and Radix Ginseng function ingredients according to 0.1～10: 0.1～10 ratio is carried out compound, is modulated into the Radix Triplostegiae Grandiflorae compound recipe function ingredients with given efficacy;
6) on Traditional health care product, cosmetics processing technique basis, introduce Radix Triplostegiae Grandiflorae compound recipe function ingredients, Radix Triplostegiae Grandiflorae functional health care product, cosmetics that preparation has specific function, the content of Radix Triplostegiae Grandiflorae function ingredients can account for 0.03～30% of total amount;
8),, obtain the pure product of serial Radix Triplostegiae Grandiflorae active substance by further component segmentation based on the Radix Triplostegiae Grandiflorae function ingredients;
9) with pure product according to certain pharmacologically active compatibility, active material of sea cucumber and Radix Ginseng active substance are according to 0.1～10: 0.1～10 ratio is carried out compound, and other drug auxiliary agent in addition, through corresponding pharmacological evaluation, exploitation Radix Triplostegiae Grandiflorae new drug preparation.
The method principle: Stichopus japonicus and Radix Ginseng all have very strong tonic effect, and have self peculiar function separately again.These effects of Radix Triplostegiae Grandiflorae derive from their intrinsic active substances.A large amount of active substances that Stichopus japonicus and Radix Ginseng include also can bring unnecessary trouble sometimes, can cause yin and yang imbalance exactly according to theory of Chinese medical science, the people is got angry, perhaps cause such as untoward reaction such as allergy, therefore directly ediblely join entirely and be not suitable for whole crowds, even some active component has good effect.
The present invention compared with prior art has following advantage:
1. Radix Triplostegiae Grandiflorae compound compatibility method described in the invention is set up on the Chinese traditional Chinese medical science of tradition and modern biotechnology basis, is traditional succession and develops, and has avoided traditional drawback of directly taking " the getting angry " of being brought.Applicant's determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs is according to the active component effectively collocation of the purpose that will reach with the two, exploitation Radix Triplostegiae Grandiflorae compound compatibility series of products.
2. the resulting product of Radix Triplostegiae Grandiflorae compound compatibility method described in the invention is selectively arranged in pairs or groups the active component in the Radix Triplostegiae Grandiflorae, and purposiveness is clear and definite, has strengthened effect.The present invention makes the complementation of Radix Triplostegiae Grandiflorae effect by reasonably allocating Stichopus japonicus and Radix Ginseng (hereinafter to be referred as Radix Triplostegiae Grandiflorae), has avoided independent use easily to produce the problem of yin and yang imbalance again simultaneously.As, the polysaccharide in the Radix Triplostegiae Grandiflorae (or oligosaccharide) is cooperated, make Radix Triplostegiae Grandiflorae polysaccharide (oligosaccharide) preparation, in order to strengthen body immunity, suppress growth of tumour cell; The Saponin polypeptide formulations, in order to fatigue alleviating, balancing blood fat, cholesterol reducing etc.The compatibility of Radix Triplostegiae Grandiflorae active component, motivated, the harmful effect that can avoid other components to bring, as influence people's endocrine, can provide enough therapeutic doses again, and absorb easily.
3. the resulting product of Radix Triplostegiae Grandiflorae compound compatibility method described in the invention, can the Radix Triplostegiae Grandiflorae lyophilized powder or extract be the basis, series of products such as exploitation Radix Triplostegiae Grandiflorae cosmetics, health product and medicine, the application of having expanded Radix Triplostegiae Grandiflorae increases added value of product greatly.
In a word, the present invention is the method for utilizing Stichopus japonicus and Radix Ginseng of a novelty, seriation.
The specific embodiment
Stichopus japonicus and Radix Ginseng are fresh products, make powder through freezing system dry powder technique.Related process conditions are the normal process conditions of corresponding operating.
Embodiment 1
Mel Radix Triplostegiae Grandiflorae cream: the Radix Triplostegiae Grandiflorae powder is mixed with the Mel of 10～20 times of mass ratioes according to 1: 1 ratio, and Fructus Jujubae, Fructus Lycii that adds 5～10 times of mass ratioes etc. refined into cream.Product can be with mixing in water for oral taking or is directly taken, and perhaps is used for cake processing.The fragrant and sweet dense abnormal smells from the patient of Radix Triplostegiae Grandiflorae self that covered of Mel is easy to make the people to accept.Mel, Stichopus japonicus, Radix Ginseng collocation simultaneously, tonifying both YIN and YANG can be augmented vigour, can fill out benefiting essence-blood again.
Embodiment 2
Radix Triplostegiae Grandiflorae skin care item: with the collagen in the Stichopus japonicus dry powder, utilize enzyme to send out and carry out the collagen extraction, be aided with the volatile oil in the Radix Ginseng that utilizes the supercritical extraction acquisition, make Radix Triplostegiae Grandiflorae protective skin cream, skin care liquid.Stichopus japonicus collagen has the effect of repair of skin, and the volatile oil in the Radix Ginseng has antioxidation.The two use of arranging in pairs or groups, collagen content accounts for total amount mass ratio 0.5～2.5%, and ginseng essential oil accounts for gross mass 0.3～1%, can improve skin quality, and delaying decrepitude of skin reduces wrinkle, reduces because the marking of the skin scar that all damages cause.
Embodiment 3
Radix Triplostegiae Grandiflorae polysaccharide goods: utilize compound enzymic preparation to extract the polysaccharide in the Radix Triplostegiae Grandiflorae dry powder, make the Radix Triplostegiae Grandiflorae polyoses capsule,, resist extraneous source of disease in order to enhancing immunity by mass ratio allotment in 1: 1; Rehabilitation after the promotion chemotherapy slows down chemical hepatic injury.
Embodiment 4
Radix Triplostegiae Grandiflorae small peptide goods: from dry powder, utilize enzyme process that little peptide is separated, according to mass ratio 0.1～1: 1 allotment, make the little peptide capsule of Radix Triplostegiae Grandiflorae, can antiinflammatory, suppress tumor, resisting fatigue.
Claims (5)
1. double ginseng composition, it is characterized in that: be made up of Stichopus japonicus and Radix Ginseng, the weight ratio of Stichopus japonicus and Radix Ginseng is 0.1～10: 0.1～10.
2. according to the described double ginseng composition of claim 1, it is characterized in that: described Stichopus japonicus and Radix Ginseng are Stichopus japonicus and ginseng freeze-dried powder.
3. the application of the described double ginseng composition of claim 1 is characterized in that: described compositions can make an addition to health product.In food or the medicine, wherein the weight content of double ginseng composition can account for 0.03～30% of product population.
4. according to the application of the described double ginseng composition of claim 3, it is characterized in that: described health product material is Mel, Fructus Jujubae and/or Fructus Lycii.
5. the application of the described double ginseng composition of claim 1, it is characterized in that: described compositions can make an addition in the cosmetics, when being used for cosmetics, its material that adopts is collagen in the Stichopus japonicus dry powder that extracts according to a conventional method and the volatile oil in the Radix Ginseng, collagen content accounts for total amount mass ratio 0.5～2.5%, and ginseng essential oil accounts for gross mass 0.3～1%.
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