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CN100336562C - Ultra strong absorption calcium alginate henatischesis dressing and its preparation method - Google Patents

Ultra strong absorption calcium alginate henatischesis dressing and its preparation method Download PDF

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Publication number
CN100336562C
CN100336562C CNB2005100392992A CN200510039299A CN100336562C CN 100336562 C CN100336562 C CN 100336562C CN B2005100392992 A CNB2005100392992 A CN B2005100392992A CN 200510039299 A CN200510039299 A CN 200510039299A CN 100336562 C CN100336562 C CN 100336562C
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calcium alginate
dressing
preparation
woven fabric
acetate
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CN1686572A (en
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褚省吾
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Taizhou Roosin Medical Product Co ltd
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Abstract

The present invention discloses an ultrahigh absorption styptic dressing made of calcium alginate, and a preparation method of the styptic dressing. The styptic dressing is prepared by the following steps: a calcium alginate fiber non-woven fabric (2) is covered on an acetate fiber fabric (1), and an anti-seepage layer (3) is covered on the other side of the acetate fiber fabric; calcium alginate fibers of the calcium alginate fiber non-woven fabric have powdery carboxymethyl chitosan. In the styptic dressing, the carboxymethyl chitosan and the calcium alginate fibers as main materials are mixed and then are prepared into a calcium alginate fiber non-woven fabric which is then covered on the acetate fiber fabric, the anti-seepage layer is put on the other side of the acetate fiber fabric, and a small quantity of needles are used for complete needle prick. The present invention has the function of solving the problems of the quick absorption, the hemostasis, the antisepsis, the ventilation and the scar prevention of wounds.

Description

一种超强吸收的海藻酸钙止血敷料及其制备方法A super-absorbable calcium alginate hemostatic dressing and its preparation method

技术领域technical field

本发明涉及一种超强吸收的海藻酸钙止血敷料及其制备方法。The invention relates to a superabsorbable calcium alginate hemostatic dressing and a preparation method thereof.

背景技术Background technique

目前临床上使用的为传统纱布敷料、网状敷料和抗菌敷料。由于它不能同时解决伤口的全面透气、渗出液的吸收和创面疤痕等问题。Traditional gauze dressings, mesh dressings and antibacterial dressings are currently used clinically. Because it can't solve the comprehensive ventilation of the wound, the absorption of the exudate and the scars of the wound at the same time.

发明内容Contents of the invention

为解决上述问题，本发明提供一种应用海藻酸钙技术的止血敷料及其制备方法。In order to solve the above problems, the present invention provides a hemostatic dressing using calcium alginate technology and a preparation method thereof.

本发明一种超强吸收的海藻酸钙止血敷料，它在醋酸纤维布上覆盖海藻酸钙纤维无纺布，在醋酸纤维布的另一侧覆盖防渗层，海藻酸钙纤维无纺布的藻酸钙纤维上设有粉状羧甲基壳聚糖。The present invention is a super-absorbable calcium alginate hemostatic dressing, which covers calcium alginate fiber non-woven fabric on acetate fiber cloth, and covers an anti-seepage layer on the other side of the acetate fiber cloth, and the calcium alginate fiber non-woven fabric Calcium alginate fibers are provided with powdered carboxymethyl chitosan.

海藻酸钙纤维上设有锌离子，防渗层为聚丙烯无纺布，羧甲基壳聚糖为粉状。The calcium alginate fiber is provided with zinc ions, the anti-seepage layer is polypropylene non-woven fabric, and carboxymethyl chitosan is in powder form.

其制备方法为：将羧甲基壳聚糖粉料与主体材料海藻酸钙纤维混合后制成海藻酸钙纤维无纺布，将海藻酸钙纤维无纺布覆盖在醋酸纤维布上，在醋酸纤维布的另一侧放置防渗层，并用少量针进行针刺粘连在一起。The preparation method is as follows: mix carboxymethyl chitosan powder with main material calcium alginate fiber to make calcium alginate fiber non-woven fabric, cover calcium alginate fiber non-woven fabric on acetate fiber cloth, The anti-seepage layer is placed on the other side of the fiber cloth, and a small amount of needles are used to stick them together.

海藻酸钙纤维具有很强的止血作用，羧甲基纤维壳聚糖具有较强的抗菌和高吸水功能，起到及时将伤口的渗出液吸收，祛除细菌生长的潜在场所。海藻酸钙具有吸附细菌，阻挡细菌通过的屏障作用，同时通过钙离子释放到伤口，产生表面凝胶，诱导血小板活化，激活伤口巨噬细胞增强创面抗御致病微生物，起到止血、加速愈合和防止疤痕形成的作用。敷料覆盖伤口后，由于醋酸纤维具有弱酸性介质，所产生的一种偏酸性的环境可以抑制各种病菌的生长，降低其感染率；海藻酸钙纤维的活性作用可经生物降解，溶解在渗透液内，使敷料保持湿润、使伤口同时保持湿润，敷料和伤口并保持完全剥离状态，纤维不留在创面上，并防止神经末梢死亡和外露，减少更换时对创口表面的损伤。醋酸纤维无纺布和聚丙烯无纺布的使用，防止了外界细菌的入侵和内界伤口渗出液的外溢而危害其它伤口。Calcium alginate fiber has a strong hemostatic effect, and carboxymethyl cellulose chitosan has strong antibacterial and high water absorption functions, which can absorb the exudate of the wound in time and eliminate the potential place for bacterial growth. Calcium alginate has the function of absorbing bacteria and preventing bacteria from passing through. At the same time, calcium ions are released to the wound to produce surface gel, induce platelet activation, activate wound macrophages, strengthen the wound surface to resist pathogenic microorganisms, and play a role in hemostasis, accelerated healing and Prevents scar formation. After the dressing covers the wound, because the acetate fiber has a weakly acidic medium, an acidic environment can inhibit the growth of various germs and reduce the infection rate; the activity of the calcium alginate fiber can be biodegraded and dissolved in the osmotic In the liquid, keep the dressing moist and keep the wound moist at the same time. The dressing and the wound are kept completely peeled off, the fibers are not left on the wound surface, and the death and exposure of the nerve endings are prevented, which reduces the damage to the wound surface during replacement. The use of acetate fiber non-woven fabric and polypropylene non-woven fabric prevents the invasion of external bacteria and the overflow of internal wound exudate from endangering other wounds.

附图说明Description of drawings

下面结合附图和实施例对本发明进行进一步说明。The present invention will be further described below in conjunction with the accompanying drawings and embodiments.

图1为本发明结构图Fig. 1 is a structural diagram of the present invention

具体实施方式Detailed ways

根据图1所示，本发明在带有锌离子的海藻酸钙纤维为主体材料加入粉状的羧甲基壳聚糖经均匀混合后用针刺机针刺成120克无纺布2，将其覆盖在50克醋酸纤维无纺布1上，将醋酸纤维布的另一侧与18克抗渗透聚丙烯无纺布3复合，并用少量针刺一遍使其粘为整体，然后切成所需块状，并经消毒便可使用。According to shown in Fig. 1, the calcium alginate fiber that has zinc ion in the present invention is main material to add the carboxymethyl chitosan of powdery form 120 gram non-woven fabrics 2 with needle-punching machine acupuncture after uniform mixing, will It is covered on 50 grams of acetate fiber non-woven fabric 1, and the other side of the acetate fiber cloth is combined with 18 grams of anti-permeation polypropylene non-woven fabric 3, and a small amount of needle punching is used to make it bonded as a whole, and then cut into required Block, and can be used after disinfection.

Claims (5)

1, a kind of calcium alginate henatischesis dressing of superabsorbent, go up covering calcium alginate fibre non-woven fabrics (2) at acetate fibre cloth (1), opposite side at acetate fibre cloth covers impervious barrier (3), and the calcium alginate fibre of calcium alginate fibre non-woven fabrics is provided with the powdery carboxymethyl chitosan.
2, dressing according to claim 1 is characterized in that calcium alginate fibre is provided with zinc ion.
3, dressing according to claim 1 is characterized in that impervious barrier is a polypropylene non-woven fabric.
4, dressing according to claim 2 is characterized in that carboxymethyl chitosan is a powdery.
5, a kind of superabsorbent the calcium alginate henatischesis dressing preparation method, with carboxymethyl chitosan with make the calcium alginate fibre non-woven fabrics after the material of main part calcium alginate fibre mixes, the calcium alginate fibre non-woven fabrics is covered on the acetate fibre cloth, opposite side at acetate fibre cloth is placed impervious barrier, and sting time with a small amount of pin, it is connected to each other as a whole.
CNB2005100392992A 2005-05-13 2005-05-13 Ultra strong absorption calcium alginate henatischesis dressing and its preparation method Expired - Lifetime CN100336562C (en)

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Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006001954B4 (en) * 2006-01-16 2013-01-03 Lohmann & Rauscher Gmbh & Co. Kg Antiseptic alginate preparation, process for their preparation, and their use
CN102499816A (en) * 2011-10-27 2012-06-20 山东颐兴医疗器械有限公司 Internal absorbable hemostasis tablet
CN103735363A (en) * 2013-12-19 2014-04-23 褚加冕 Manufacturing method for medical high-hygroscopicity hemostasis dressing
CN103768650A (en) * 2014-01-26 2014-05-07 深圳市博立生物材料有限公司 Wound regenerating and repairing bandage and manufacture method thereof
CN104189942A (en) * 2014-09-09 2014-12-10 东华大学 Antibacterial wound dressing and preparation method thereof
CN105664224B (en) * 2016-02-25 2019-05-28 中国人民解放军军事医学科学院卫生装备研究所 A kind of compound alginic acid dressing of low molecular weight carboxymethyl chitosan and preparation method thereof
CN107468674A (en) * 2017-09-18 2017-12-15 泰州市榕兴医疗用品股份有限公司 Honey sterilization bandage and preparation method thereof
CN108992232A (en) * 2018-08-24 2018-12-14 常州市第二人民医院 A kind of orthopedic rehabilitation training auxiliary device

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4793337A (en) * 1986-11-17 1988-12-27 E. R. Squibb & Sons, Inc. Adhesive structure and products including same
CN1065138C (en) * 1996-10-21 2001-05-02 杭州仁德医药有限公司 Method for manufacture seaweed acid calcium medicated plaster and seaweed acid calcium fibre nonwoven fabrics
CN1080784C (en) * 1996-12-29 2002-03-13 冯鸿城 Active wound dressing, zinc-calcium alginate fiber nonwoven fabric and its preparing technology

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4793337A (en) * 1986-11-17 1988-12-27 E. R. Squibb & Sons, Inc. Adhesive structure and products including same
CN1065138C (en) * 1996-10-21 2001-05-02 杭州仁德医药有限公司 Method for manufacture seaweed acid calcium medicated plaster and seaweed acid calcium fibre nonwoven fabrics
CN1080784C (en) * 1996-12-29 2002-03-13 冯鸿城 Active wound dressing, zinc-calcium alginate fiber nonwoven fabric and its preparing technology

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Assignee: ROOSIN MEDICAL CO.,LTD.

Assignor: Chu Shengwu

Contract fulfillment period: 2009.7.3 to 2017.7.3

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Denomination of invention: Ultra strong absorption calcium alginate henatischesis dressing and its preparation method

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