CN109979536A - It is a kind of based on DNA bar code to the identification method of species - Google Patents
It is a kind of based on DNA bar code to the identification method of species Download PDFInfo
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- 238000000034 method Methods 0.000 title claims abstract description 61
- 108091028043 Nucleic acid sequence Proteins 0.000 claims abstract description 75
- 108020004414 DNA Proteins 0.000 claims abstract description 67
- 230000003252 repetitive effect Effects 0.000 claims abstract description 37
- 241000894007 species Species 0.000 claims description 86
- 241000196324 Embryophyta Species 0.000 claims description 12
- 238000007596 consolidation process Methods 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- JNRLEMMIVRBKJE-UHFFFAOYSA-N 4,4'-Methylenebis(N,N-dimethylaniline) Chemical compound C1=CC(N(C)C)=CC=C1CC1=CC=C(N(C)C)C=C1 JNRLEMMIVRBKJE-UHFFFAOYSA-N 0.000 description 2
- 230000000694 effects Effects 0.000 description 1
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- 108090000623 proteins and genes Proteins 0.000 description 1
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Abstract
The invention discloses a kind of based on DNA bar code to the identification method of species, and in particular to species identification method field includes the following three types identification method: identification method one: carrying out arrangement database according to the living environment of species and department；Identification method two: according to the number of base carries out establishing tree shaped data library in ATCG tetra- in DNA sequence dna；Identification method three: DNA bar code is generated according to the repetitive sequence data in DNA sequence dna, carries out establishing database.The present invention utilizes identification method one, can be used in use when the living environment and department of probably knowing species, identifies fast speed；It using identification method two, is used in the case where can be used in not knowing any information of species, identifies fast speed；It using identification method three, is used in the case where can be used in not knowing any information of species, and when DNA sequence dna is imperfect, directly repetitive sequence can be taken to be identified, identifies fast speed.
Description
Technical field
The present invention relates to species identification method and technology fields, it is more particularly related to which a kind of be based on DNA bar code
To the identification method of species.
Background technique
DNA bar code (DNABarcoding) technology is using a segment standard, shorter DNA sequence dna as molecule mark
Note, by being scanned to genes one or more in organism, to realize the technology of species identification.DNA bar code at present
Technology has been widely used for the classification and identification of biology, is a kind of easy, efficient, accurate species identification technology.
But in some species identifications, since its possible DNA is destroyed, lead to not extract complete DNA sequence
Column, it is therefore desirable to a kind of method that can be identified for species under different situations, and very because of tellurian species
It is more, therefore in identification, it is also necessary to it being capable of Rapid identification.
Summary of the invention
In order to overcome the drawbacks described above of the prior art, the embodiment of the present invention provides one kind based on DNA bar code to species
Identification method, by utilize identification method one, can be used in use when the living environment and department of probably knowing species, identify
Fast speed；Using identification method two, used in the case where can be used in not knowing any information of species, identification speed compared with
Fastly；It using identification method three, is used in the case where can be used in not knowing any information of species, and when DNA sequence dna is imperfect
When, directly repetitive sequence can be taken to be identified, identify fast speed, three kinds of identification methods are applicable not only under a variety of different situations
Species identification, and can be realized Rapid identification, identification method multiplicity can be selected voluntarily.
To achieve the above object, the invention provides the following technical scheme: it is a kind of based on DNA bar code to the identification side of species
Method includes the following three types identification method:
(1) steps are as follows for the specific identification method of identification method one:
Step 1: acquiring one section of RNA sequence of accurately various species, i.e. DNA sequence dna first, each object is generated
Kind DNA bar code, the type and specifying information of species are stored in this DNA bar code；
Step 2: the DNA bar code for acquiring and generating in step 1 is stored separately according to department described in species,
The DNA bar code of each department different plant species is respectively stored in different databases；
Step 3: each database root is carried out edit code according to the information of species department；
Step 4: the database that different department species DNA bar codes store is carried out consolidation again, according to water, land and air three
Kind living environment progress carries out arrangement storage to the database after coding again, is respectively stored in three retrieval modules, then
It is uploaded to identification platform；
Step 5: taking the DNA sequence dna of identification species, the environment then survived according to species, into mirror when specific identification
Fixed platform finds corresponding retrieval module, inputs the DNA sequence dna for needing to identify species in retrieval module again, scans for
Comparison, quickly finds corresponding DNA bar code, then checks the type stored in DNA bar code and specifying information, can be complete
At the identification of species；
Step 6: being directly entered in corresponding retrieval module when knowing the specific affiliated department of species, inputting its DNA
Sequence is encoded according to the database of species department, and automatically retrieval is to the coded data library, to carry out in this database quick
It searches；
(2) steps are as follows for the specific identification method of identification method two:
Step 1: acquisition different plant species section of DNA sequence, and by its DNA sequence dna in ATCG tetra- base number
It is counted, and DNA bar code is generated according to the data of statistics (such as A9 T7 C5 G7), be stored with object in this DNA bar code
The type and specifying information of kind；
After Step 2: by the DNA bar code for acquiring and generating in step 1 with A1, A2, A3 ..., An is distinguished, store respectively
With A1, A2, A3 ... An be number No.1 database in, then again by the DNA bar code in each No.1 database with
After T1, T2, T3 ... Tn are distinguished, it is respectively stored in T1, T2, T3 ... in the two number libraries that Tn is number, i.e., is started with A
No.1 databases store up multiple two number libraries started with T, similarly, then opened being divided into each two number library with C
The route data base of head will finally be divided into the four number libraries started with G, entire DNA bar code number in each route data base
Sort out according to library in tree-shaped layering；
Step 3: when specific search, of ATCG directly in the DNA sequence dna that identification platform input needs to identify species
Number, then platform is corresponded to automatically in ATCG the same number of four number library, consequently, it is possible to finding multiple ATCG number phases
Same DNA sequence dna；
Step 4: the DNA sequence dna of entire identification species is fully entered again at this time, with the DNA being retrieved in step 3
DNA sequence dna in bar code compares, to find corresponding DNA sequence dna, according to this DNA bar code, checks species information；
(3) steps are as follows for the specific identification method of identification method three:
Step 1: the section of DNA sequence of acquisition different plant species, and the repetitive sequence data in its DNA sequence dna are generated
DNA bar code, repetitive sequence are divided into tandem repetitive sequence and interspersed repetitive sequence；
Step 2: the DNA bar code of species is divided into two databases according to tandem repetitive sequence and interspersed repetitive sequence；
Step 3: taking the repetitive sequence in the DNA sequence dna of identification species, then judge that repetitive sequence is for tandem sequence repeats sequence
Column or interspersed repetitive sequence, specifically when search, directly input needs to identify object in two large database concepts of identification platform respectively
Repetitive sequence in the DNA sequence dna of kind；
Step 4: if be to seek out multiple DNA bar codes, then the DNA sequence dnas of entire identification species fully entered, with
The DNA sequence dna being retrieved in step 3 compares, to find corresponding DNA sequence dna, according to this DNA bar code, checks
Species information.
In a preferred embodiment, a kind of side for acquiring species DNA sequence dna of the step of three kinds of identification methods
Method are as follows: obtain the DNA sequence dna of different plant species by internet checking, inquiry pertinent texts or in research laboratory.
Technical effect and advantage of the invention:
1, the present invention utilizes identification method one: carrying out arrangement database, Neng Gouyong according to the living environment of species and department
Fast speed is identified in use when probably knowing the living environment and department of species；Utilize identification method two: according to DNA sequence dna
The number of base carries out establishing tree shaped data library in middle ATCG tetra-, makes in the case where can be used in not knowing any information of species
With identification fast speed；It utilizes identification method three: generating DNA bar code according to the repetitive sequence data in DNA sequence dna, carry out
Database is established, is used in the case where can be used in not knowing any information of species, and when DNA sequence dna is imperfect, it can be straight
It picks up repetitive sequence to be identified, identifies fast speed；
2, three kinds of identification methods of the invention are applicable not only to the species identification under a variety of different situations, and can be realized fast
Speed identification, identification method multiplicity, can voluntarily select.
Specific embodiment
Below in conjunction with the embodiment in the present invention, technical solution in the embodiment of the present invention is carried out clearly and completely
Description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based on this hair
Embodiment in bright, every other implementation obtained by those of ordinary skill in the art without making creative efforts
Example, shall fall within the protection scope of the present invention.
Embodiment 1:
The present invention provides a kind of based on DNA bar code to the identification method of species
Steps are as follows for the specific identification method of identification method one:
Step 1: acquiring one section of RNA sequence of accurately various species, i.e. DNA sequence dna first, each object is generated
Kind DNA bar code, the type and specifying information of species are stored in this DNA bar code；
Step 2: the DNA bar code for acquiring and generating in step 1 is stored separately according to department described in species,
The DNA bar code of each department different plant species is respectively stored in different databases；
Step 3: each database root is carried out edit code according to the information of species department；
Step 4: the database that different department species DNA bar codes store is carried out consolidation again, according to water, land and air three
Kind living environment progress carries out arrangement storage to the database after coding again, is respectively stored in three retrieval modules, then
It is uploaded to identification platform；
Step 5: taking the DNA sequence dna of identification species, the environment then survived according to species, into mirror when specific identification
Fixed platform finds corresponding retrieval module, inputs the DNA sequence dna for needing to identify species in retrieval module again, scans for
Comparison, quickly finds corresponding DNA bar code, then checks the type stored in DNA bar code and specifying information, can be complete
At the identification of species；
Step 6: being directly entered in corresponding retrieval module when knowing the specific affiliated department of species, inputting its DNA
Sequence is encoded according to the database of species department, and automatically retrieval is to the coded data library, to carry out in this database quick
It searches, searches more quick and convenient；
By this identification method, can be used in use when the living environment and department of probably knowing species, identification speed compared with
Fastly；
Embodiment 2:
The present invention provides a kind of based on DNA bar code to the identification method of species
Steps are as follows for the specific identification method of identification method two:
Step 1: acquisition different plant species section of DNA sequence, and by its DNA sequence dna in ATCG tetra- base number
It is counted, and DNA bar code is generated according to the data of statistics (such as A9 T7 C5 G7), be stored with object in this DNA bar code
The type and specifying information of kind；
After Step 2: by the DNA bar code for acquiring and generating in step 1 with A1, A2, A3 ..., An is distinguished, store respectively
With A1, A2, A3 ... An be number No.1 database in, then again by the DNA bar code in each No.1 database with
After T1, T2, T3 ... Tn are distinguished, it is respectively stored in T1, T2, T3 ... in the two number libraries that Tn is number, i.e., is started with A
No.1 databases store up multiple two number libraries started with T, similarly, then opened being divided into each two number library with C
The route data base of head will finally be divided into the four number libraries started with G, entire DNA bar code number in each route data base
Sort out according to library in tree-shaped layering；
Step 3: when specific search, of ATCG directly in the DNA sequence dna that identification platform input needs to identify species
Number, then platform is corresponded to automatically in ATCG the same number of four number library, consequently, it is possible to finding multiple ATCG number phases
Same DNA sequence dna；
Step 4: the DNA sequence dna of entire identification species is fully entered again at this time, with the DNA being retrieved in step 3
DNA sequence dna in bar code compares, to find corresponding DNA sequence dna, according to this DNA bar code, checks species information；
It by this identification method, is used in the case where can be used in not knowing any information of species, identifies fast speed；
Embodiment 3:
The present invention provides a kind of based on DNA bar code to the identification method of species
Steps are as follows for the specific identification method of identification method three:
Step 1: the section of DNA sequence of acquisition different plant species, and the repetitive sequence data in its DNA sequence dna are generated
DNA bar code, repetitive sequence are divided into tandem repetitive sequence and interspersed repetitive sequence；
Step 2: the DNA bar code of species is divided into two databases according to tandem repetitive sequence and interspersed repetitive sequence；
Step 3: taking the repetitive sequence in the DNA sequence dna of identification species, then judge that repetitive sequence is for tandem sequence repeats sequence
Column or interspersed repetitive sequence, specifically when search, directly input needs to identify object in two large database concepts of identification platform respectively
Repetitive sequence in the DNA sequence dna of kind；
Step 4: if be to seek out multiple DNA bar codes, then the DNA sequence dnas of entire identification species fully entered, with
The DNA sequence dna being retrieved in step 3 compares, to find corresponding DNA sequence dna, according to this DNA bar code, checks
Species information.
By this identification method, used in the case where can be used in not knowing any information of species, and when DNA sequence dna not
When complete, directly repetitive sequence can be taken to be identified, identify fast speed.
Embodiment 4:
The step of three kinds of identification methods it is a kind of acquire species DNA sequence dna method are as follows: pass through internet checking, inquiry
Pertinent texts or obtain the DNA sequence dna of different plant species in research laboratory, information collection it is various informative, can collect wider
Information, and the DNA sequence dna differently collected can be checked, improve the accuracy of DNA sequence dna information, protected
Demonstrate,prove the high accurancy and precision of later period identification.
Last: the foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention, all in the present invention
Spirit and principle within, any modification, equivalent replacement, improvement and so on, should be included in protection scope of the present invention it
It is interior.
Claims (2)
1. it is a kind of based on DNA bar code to the identification method of species, it is characterised in that: include the following three types identification method:
(1) steps are as follows for the specific identification method of identification method one:
Step 1: acquiring one section of RNA sequence of accurately various species, i.e. DNA sequence dna first, each species are generated
DNA bar code is stored with the type and specifying information of species in this DNA bar code；
Step 2: the DNA bar code for acquiring and generating in step 1 is stored separately according to department described in species, each
The DNA bar code of department different plant species is respectively stored in different databases；
Step 3: each database root is carried out edit code according to the information of species department；
Step 4: the database that different department species DNA bar codes store is carried out consolidation again, according to three kinds of lifes of water, land and air
Dis environment progress carries out arrangement storage to the database after coding again, is respectively stored in three retrieval modules, then uploads
To identification platform；
Step 5: taking the DNA sequence dna of identification species when specific identification, the environment then survived according to species is flat into identification
Platform finds corresponding retrieval module, inputs the DNA sequence dna for needing to identify species in retrieval module again, scans for comparing,
Corresponding DNA bar code is quickly found, the type stored in DNA bar code and specifying information is then checked, object can be completed
The identification of kind；
Step 6: be directly entered in corresponding retrieval module when knowing the specific affiliated department of species, input its DNA sequence dna,
It is encoded according to the database of species department, automatically retrieval is to the coded data library, to quickly be searched in this database；
(2) steps are as follows for the specific identification method of identification method two:
Step 1: the section of DNA sequence of acquisition different plant species, and by the number of base carries out in ATCG tetra- in its DNA sequence dna
Statistics, and DNA bar code is generated according to the data of statistics (such as A9T7C5G7), the kind of species is stored in this DNA bar code
Class and specifying information；
Step 2: by the DNA bar code for acquiring and generating in step 1 with A1, A2, A3 ... An distinguish after, be respectively stored in
A1, A2, A3 ... An be number No.1 database in, then again by the DNA bar code in each No.1 database with T1,
It after T2, T3 ... Tn are distinguished, is respectively stored in T1, T2, T3 ... in the two number libraries that Tn is number, i.e., with A beginning
No.1 databases store up multiple two number libraries started with T, similarly, then are started being divided into each two number library with C
Route data base, finally will be divided into each route data base with G start four number libraries, entire DNA bar code data
Sort out in tree-shaped layering in library；
Step 3: when specific search, the number of ATCG directly in the DNA sequence dna that identification platform input needs to identify species, so
Rear platform is corresponded to automatically in ATCG the same number of four number library, consequently, it is possible to it is the same number of to find multiple ATCG
DNA sequence dna；
Step 4: the DNA sequence dna of entire identification species is fully entered again at this time, with the DNA bar shaped being retrieved in step 3
DNA sequence dna in code compares, to find corresponding DNA sequence dna, according to this DNA bar code, checks species information；
(3) steps are as follows for the specific identification method of identification method three:
Step 1: the section of DNA sequence of acquisition different plant species, and the repetitive sequence data in its DNA sequence dna are generated into DNA item
Shape code, repetitive sequence are divided into tandem repetitive sequence and interspersed repetitive sequence；
Step 2: the DNA bar code of species is divided into two databases according to tandem repetitive sequence and interspersed repetitive sequence；
Step 3: take identification species DNA sequence dna in repetitive sequence, then judge repetitive sequence be for tandem repetitive sequence also
It is interspersed repetitive sequence, specifically when search, directly input needs to identify species in two large database concepts of identification platform respectively
Repetitive sequence in DNA sequence dna；
Step 4: if be to seek out multiple DNA bar codes, then the DNA sequence dnas of entire identification species fully entered, with step
The DNA sequence dna being retrieved in three compares, to find corresponding DNA sequence dna, according to this DNA bar code, checks species
Information.
2. it is according to claim 1 it is a kind of based on DNA bar code to the identification method of species, it is characterised in that: described three
The step of kind of identification method a kind of method for acquiring species DNA sequence dna are as follows: by internet checking, inquiry pertinent texts or
The DNA sequence dna of research laboratory's acquisition different plant species.
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Cited By (1)
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| CN111161800A (en) * | 2019-12-30 | 2020-05-15 | 云舟生物科技（广州）有限公司 | Method, system, storage medium, and electronic device for diagnosing sequence of gene vector |
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