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CN109859600A - Ultrasound-guided breast tumor puncture model and preparation method thereof - Google Patents

Ultrasound-guided breast tumor puncture model and preparation method thereof Download PDF

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Publication number
CN109859600A
CN109859600A CN201910147274.6A CN201910147274A CN109859600A CN 109859600 A CN109859600 A CN 109859600A CN 201910147274 A CN201910147274 A CN 201910147274A CN 109859600 A CN109859600 A CN 109859600A
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breast tumor
phantom
suspension
embedded
puncture model
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CN109859600B (en
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何萍
崔立刚
李国洋
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Peking University Third Hospital Peking University Third Clinical Medical College
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Peking University Third Hospital Peking University Third Clinical Medical College
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Abstract

本发明涉及一种超声引导下乳腺肿物穿刺模型及其制备方法，包括乳腺肿物仿体及包埋仿体，乳腺肿物仿体设置于包埋仿体内；乳腺肿物仿体的包埋位置根据需要进行设置；乳腺肿物仿体的硬度大于包埋仿体的硬度。本申请的乳腺肿物仿体及包埋仿体均通过聚乙烯醇，纤维素及去离子水制备，本申请的乳腺肿物仿体包埋于与肿物仿体相同材质的包埋仿体后，超声可显示出肿物，易于区分，该模型十分适合于作为模拟超声引导穿刺教学的模型。

The invention relates to an ultrasound-guided breast tumor puncture model and a preparation method thereof, including a breast tumor phantom and an embedded phantom, wherein the breast tumor phantom is set in the embedded phantom; The position is set as desired; the hardness of the breast tumor phantom is greater than that of the embedded phantom. The breast tumor phantom and the embedded phantom of the present application are prepared by polyvinyl alcohol, cellulose and deionized water, and the breast tumor phantom of the present application is embedded in the embedded phantom of the same material as the tumor phantom. After ultrasound, the tumor can be displayed and it is easy to distinguish. This model is very suitable as a model for simulating ultrasound-guided puncture teaching.

Description

Ultrasound guidance breast tumor puncturing pattern and preparation method thereof
Technical field
The present invention relates to medical lecture model technical fields, particularly relate to a kind of ultrasound guidance breast tumor puncturing pattern And preparation method thereof.
Background technique
Ultrasound training project in recent years emerging as one on Chinese ultrasound diagnosis circle is widely being promoted, the increasing of demand Add, the quality of training also more and more attention has been paid to, ultrasound training in, ultrasound guidance breast tumor puncture technology grasp at For difficult point, since ultrasonic image and entity dissection have a certain difference, in actual operation to student's independent operation and from now on There is certain challenge to image cognition understanding.
Previously unpromising ultrasonic doctor provides the training that special and comprehensive ultrasound guidance breast tumor punctures, but Using the mode of " seeing one, teach one, do one ".High seniority attending physician, secondary master i.e. generally by having grasped this technical ability Appoint doctor or the chief physician directly directly upper hand operation after the empathic learning of interventional procedure room with young attending doctor.It is this The different clinical scenarios that training pattern can not be likely encountered for clinic provide sufficient preparation.
Summary of the invention
The object of the present invention is to provide a kind of ultrasound guidance breast tumor puncturing patterns and preparation method thereof, and ultrasound is allowed to cure Teacher, by utilizing model training, can skillfully grasp the puncture of ultrasound guidance breast tumor before entering clinical practice operation The gimmick of operation improves the accuracy of puncture, reduces the time of clinical manipulation, the sense of discomfort and complication of patient.This is for doctor Suffer from both sides with greater significance, the safety and validity of clinical position can be effectively improved.
The present invention is achieved by the following technical solutions:
A kind of ultrasound guidance breast tumor puncturing pattern, including breast tumor imitate body and embed imitative body, and the mammary gland is swollen It is imitative internal that the imitative body of object is set to embedding；The embedding position that the breast tumor imitates body is configured as needed；
The material that the breast tumor imitates body is identical as the imitative material of body of the embedding；The breast tumor imitates the hardness of body Greater than the hardness for embedding imitative body.
The outer surface that the breast tumor imitates body is smooth outer surface or Non-smooth surface outer surface.
The size and shape of the imitative body of the breast tumor are identical or not identical.
The color that breast tumor imitates body is different from the imitative color of body is embedded.
A kind of preparation method of any of the above-described ultrasound guidance breast tumor puncturing pattern, imitates body including breast tumor Preparation and the preparation for embedding imitative body；
The breast tumor imitate body preparation the following steps are included:
1) PVA powder is poured into deionized water, is stirred continuously to thorough dissolution, and solution is heated to the first setting temperature Degree, adds cellulose and is sufficiently stirred to form suspension；
2) suspension of step 1) is placed in refrigerator after freezing the first setting time to be placed in again under room temperature and is thawed, is formed with The colloid of certain elasticity；
3) colloid after step 2) defrosting is again placed in refrigerator after freezing first setting time and is placed under room temperature again It thaws；Obtain the imitative body colloidal materials of breast tumor；
4) body is imitated using Mold Making size and variform breast tumor；
The preparation for embedding imitative body the following steps are included:
5) PVA powder is poured into deionized water, is stirred continuously to thorough dissolution, and solution is heated to the second setting temperature Degree, adds cellulose and is sufficiently stirred to form suspension；
6) suspension of step 5) is poured into mold, the breast tumor of step 4) is imitated into body and is fixed in the mold It in suspension, is placed in refrigerator and freezes the second setting time, then be placed under room temperature and thaw, breast tumor puncturing pattern is made.
It further, further include addition coloring agent in step 1).
Further, including suspension deaeration step before the step 2) and before the step 6).
Further, first setting time is identical as second setting time, is 10-14 hours；Described One set temperature and second set temperature it is identical be 70 DEG C -90 DEG C.
Further, including repeat step 3) once or more.
Further, the PVA dosage in the step 1) accounts for the 5%-20% of suspension total weight, and cellulose accounts for suspension The 1%-5% of total weight；
PVA dosage in the step 5) accounts for the 5%-20% of suspension total weight, and cellulose accounts for suspension total weight 1%-5%.
The beneficial effects of the present invention are:
After the imitative body of breast tumor of the invention is embedded in the imitative body of embedding for imitating body same material with swollen object, ultrasound can be shown Swollen object, easily distinguishable, which is quite suitable for the model as simulation ultrasound guided puncture teaching.
The material type of this model is few, prepares simple and convenient and at low cost, promotes convenient for a wide range of.
Detailed description of the invention
Fig. 1 is breast tumor puncturing pattern schematic diagram.
Description of symbols
1 embeds imitative body, and 2 breast tumors imitate body, 3 push pins.
Specific embodiment
Carry out the technical solution that the present invention will be described in detail by the following examples, embodiment below is merely exemplary, only It can be used to explanation and illustration technical solution of the present invention, and be not to be construed as the limitation to technical solution of the present invention.
The application provides a kind of ultrasound guidance breast tumor puncturing pattern, as shown in Figure 1, including that breast tumor imitates body 2 And imitative body 1 is embedded, it is imitative internal that the imitative body of breast tumor is set to embedding；The embedding position that breast tumor imitates body is set as needed It sets；
The hardness that breast tumor imitates body is greater than the hardness for embedding imitative body.
The material that breast tumor imitates body is identical as the imitative material of body is embedded.
The outer surface that breast tumor imitates body is smooth outer surface or Non-smooth surface outer surface.
Breast tumor imitate system as when coloring agent is added, with embed imitative body difference.
The size and shape of the imitative body of breast tumor are identical or not identical.
The application also provides a kind of preparation method of ultrasound guidance breast tumor puncturing pattern, including breast tumor imitates body Preparation and embed the preparation of imitative body；
Breast tumor imitate body preparation the following steps are included:
1) at room temperature, PVA (polyvinyl alcohol) powder is poured into deionized water, is stirred continuously to thorough dissolution, and will Solution is heated to 70 DEG C -90 DEG C, adds cellulose and is sufficiently stirred to form suspension；In the present embodiment, cellulose is straight Diameter range is 10-30 μm, and in suspension, PVA accounts for the 5%-20% of suspension total weight, and cellulose accounts for suspension total weight 1%-5%.It in the present embodiment, further include that coloring agent is added in suspension, to be distinguished with the imitative body of embedding, in the application Each embodiment in, the color of coloring agent determines as needed.
2) it after the suspension degasification of step 1), will be placed in -20 DEG C of refrigerators after freezing 10-14 hours and be placed in room temperature again (about Be 20 DEG C) under thaw, be formed with the colloid of certain elasticity.One freeze-thaw process is considered as a cycle.
3) colloid is again placed in -20 DEG C of refrigerators and freezes 10-14 hours after step 2) being thawed, after be placed under room temperature and solve again Freeze；Obtain the imitative body colloidal materials of breast tumor.
Under normal circumstances, the period that the imitative body of breast tumor passes through is more, and hardness is bigger, i.e., by repeating step 3) come real The adjustment of body hardness is now imitated breast tumor；Equally, the content of PVA is higher, and the hardness that breast tumor imitates body is bigger, passes through freezing Period or material mixture ratio adjust the hardness that breast tumor imitates body, to prepare the imitative body of different hardness.
4) body is imitated using Mold Making size and variform breast tumor, and added when breast tumor imitates the product of body Enter coloring agent, punctures whether materials succeed to observe.
Embed the preparation of imitative body the following steps are included:
5) at room temperature, PVA powder is poured into deionized water, is stirred continuously to thorough dissolution, and solution is heated to It 70 DEG C -90 DEG C, adds cellulose and is sufficiently stirred to form suspension；In suspension, PVA accounts for the 5%- of suspension total weight 20%, cellulose accounts for the 1%-5% of suspension total weight.
6) it by the suspension of step 5), pours into mold, the breast tumor of step 4) is imitated into body, mould is fixed on by push pin 3 In suspension in tool, breast tumor is simulated by controlling the length of push pin 3 and does not show depth in the imitative body of embedding, in degasification Afterwards, freezing 10-14 hours in -20 DEG C of refrigerators are placed in, then is placed under room temperature (about 20 DEG C) and thaws, breast tumor is made and punctures mould Type.
Embodiment 1
A kind of preparation method of ultrasound guidance breast tumor puncturing pattern, the preparation and embedding of body are imitated including breast tumor The preparation of imitative body；
1) at room temperature, PVA (polyvinyl alcohol) powder is poured into deionized water, is stirred continuously to thorough dissolution, and will Solution is heated to 70 DEG C, adds cellulose and coloring agent and is sufficiently stirred to form suspension；In suspension, PVA accounts for suspension The 5% of total weight, cellulose account for the 1% of suspension total weight.
2) it after the suspension degasification of step 1), will be placed in -20 DEG C of refrigerators after freezing 10 hours to be placed in again under room temperature and thaw, It is formed with the colloid of certain elasticity.
3) colloid is again placed in -20 DEG C of refrigerators and freezes 10 hours after step 2) being thawed, after be placed under room temperature and thaw again； Obtain the imitative body colloidal materials of breast tumor.
4) body is imitated using Mold Making size and variform breast tumor, and added when breast tumor imitates the production of body Enter coloring agent, punctures whether materials succeed to observe.
5) at room temperature, PVA powder is poured into deionized water, is stirred continuously to thorough dissolution, and solution is heated to It 70 DEG C, adds cellulose and is sufficiently stirred to form suspension；In suspension, PVA accounts for the 5% of suspension total weight, cellulose Account for the 1% of suspension total weight.
6) it by the suspension of step 5), pours into mold, the breast tumor of step 4) is imitated into body, mould is fixed on by push pin In suspension in tool, with the degassed, freezing 10 hours in -20 DEG C of refrigerators is placed in, then be placed under room temperature and thaw, it is swollen that mammary gland is made Object puncturing pattern.
Embodiment 2
A kind of preparation method of ultrasound guidance breast tumor puncturing pattern, the preparation and embedding of body are imitated including breast tumor The preparation of imitative body；
1) at room temperature, PVA (polyvinyl alcohol) powder is poured into deionized water, is stirred continuously to thorough dissolution, and will Solution is heated to 80 DEG C, adds cellulose and coloring agent and is sufficiently stirred to form suspension；In suspension, PVA accounts for suspension The 10% of total weight, cellulose account for the 3% of suspension total weight.
2) it after the suspension degasification of step 1), will be placed in -20 DEG C of refrigerators after freezing 12 hours to be placed in again under room temperature and thaw, It is formed with the colloid of certain elasticity.
3) colloid is again placed in -20 DEG C of refrigerators and freezes 12 hours after step 2) being thawed, after be placed under room temperature and thaw again； Step 3) once or more is repeated again, obtains the imitative body colloidal materials of breast tumor.
4) body is imitated using Mold Making size and variform breast tumor, and added when breast tumor imitates the production of body Enter coloring agent, punctures whether materials succeed to observe.
5) at room temperature, PVA powder is poured into deionized water, is stirred continuously to thorough dissolution, and solution is heated to It 80 DEG C, adds cellulose and is sufficiently stirred to form suspension；In suspension, PVA accounts for the 10% of suspension total weight, cellulose Account for the 3% of suspension total weight.
6) it by the suspension of step 5), pours into mold, the breast tumor of step 4) is imitated into body, mould is fixed on by push pin In suspension in tool, with the degassed, freezing 12 hours in -20 DEG C of refrigerators is placed in, then be placed under room temperature and thaw, it is swollen that mammary gland is made Object puncturing pattern.
Embodiment 3
A kind of preparation method of ultrasound guidance breast tumor puncturing pattern, the preparation and embedding of body are imitated including breast tumor The preparation of imitative body；
1) at room temperature, PVA (polyvinyl alcohol) powder is poured into deionized water, is stirred continuously to thorough dissolution, and will Solution is heated to 90 DEG C, adds cellulose and coloring agent and is sufficiently stirred to form suspension；In suspension, PVA accounts for suspension The 20% of total weight, cellulose account for the 5% of suspension total weight.
2) it after the suspension degasification of step 1), will be placed in -20 DEG C of refrigerators after freezing 14 hours to be placed in again under room temperature and thaw, It is formed with the colloid of certain elasticity.
3) colloid is again placed in -20 DEG C of refrigerators and freezes 14 hours after step 2) being thawed, after be placed under room temperature and thaw again； It repeats step 3) twice, obtains the imitative body colloidal materials of breast tumor.
4) body is imitated using Mold Making size and variform breast tumor, and added when breast tumor imitates the production of body Enter coloring agent, punctures whether materials succeed to observe.
5) at room temperature, PVA powder is poured into deionized water, is stirred continuously to thorough dissolution, and solution is heated to It 80 DEG C, adds cellulose and is sufficiently stirred to form suspension；In suspension, PVA accounts for the 20% of suspension total weight, cellulose Account for the 5% of suspension total weight.
6) it by the suspension of step 5), pours into mold, the breast tumor of step 4) is imitated into body, mould is fixed on by push pin In suspension in tool, with the degassed, freezing 14 hours in -20 DEG C of refrigerators is placed in, then be placed under room temperature and thaw, it is swollen that mammary gland is made Object puncturing pattern.
Embodiment 4
A kind of preparation method of ultrasound guidance breast tumor puncturing pattern, the preparation and embedding of body are imitated including breast tumor The preparation of imitative body；
1) at room temperature, PVA (polyvinyl alcohol) powder is poured into deionized water, is stirred continuously to thorough dissolution, and will Solution is heated to 80 DEG C, adds cellulose and coloring agent and is sufficiently stirred to form suspension；In suspension, PVA accounts for suspension The 10% of total weight, cellulose account for the 3% of suspension total weight.
2) it after the suspension degasification of step 1), will be placed in -20 DEG C of refrigerators after freezing 12 hours to be placed in again under room temperature and thaw, It is formed with the colloid of certain elasticity.
3) colloid is again placed in -20 DEG C of refrigerators and freezes 12 hours after step 2) being thawed, after be placed under room temperature and thaw again； And step 3) once or more is repeated, obtain the imitative body colloidal materials of breast tumor.
4) body is imitated using Mold Making size and variform breast tumor, and added when breast tumor imitates the production of body Enter coloring agent, punctures whether materials succeed to observe.
5) at room temperature, PVA powder is poured into deionized water, is stirred continuously to thorough dissolution, and solution is heated to It 80 DEG C, adds cellulose and is sufficiently stirred to form suspension；In suspension, PVA accounts for the 10% of suspension total weight, cellulose Account for the 3% of suspension total weight.
6) it by the suspension of step 5), pours into mold, the breast tumor of step 4) is imitated into body, mould is fixed on by push pin In suspension in tool, with the degassed, freezing 12 hours in -20 DEG C of refrigerators is placed in, then be placed under room temperature and thaw, it is swollen that mammary gland is made Object puncturing pattern.
Embodiment 5
A kind of preparation method of ultrasound guidance breast tumor puncturing pattern, the preparation and embedding of body are imitated including breast tumor The preparation of imitative body；
1) at room temperature, PVA (polyvinyl alcohol) powder is poured into deionized water, is stirred continuously to thorough dissolution, and will Solution is heated to 80 DEG C, adds cellulose and is sufficiently stirred to form suspension；In suspension, PVA accounts for suspension total weight 15%, cellulose accounts for the 5% of suspension total weight.
2) it after the suspension degasification of step 1), will be placed in -20 DEG C of refrigerators after freezing 12 hours to be placed in again under room temperature and thaw, It is formed with the colloid of certain elasticity.
3) colloid is again placed in -20 DEG C of refrigerators and freezes 12 hours after step 2) being thawed, after be placed under room temperature and thaw again； Step 3) once or more is repeated, the imitative body colloidal materials of breast tumor are obtained.
4) body is imitated using Mold Making size and variform breast tumor, punctures whether materials succeed to observe.
5) at room temperature, PVA powder is poured into deionized water, is stirred continuously to thorough dissolution, and solution is heated to It 80 DEG C, adds cellulose and is sufficiently stirred to form suspension；In suspension, PVA accounts for the 10% of suspension total weight, cellulose Account for the 3% of suspension total weight.
6) it by the suspension of step 5), pours into mold, the breast tumor of step 4) is imitated into body, mould is fixed on by push pin In suspension in tool, with the degassed, freezing 12 hours in -20 DEG C of refrigerators is placed in, then be placed under room temperature and thaw, it is swollen that mammary gland is made Object puncturing pattern.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding And deformation, the scope of the present invention are extremely equally limited by appended claims.

Claims (10)

1.一种超声引导下乳腺肿物穿刺模型，其特征在于，包括乳腺肿物仿体及包埋仿体，所述乳腺肿物仿体设置于包埋仿体内；所述乳腺肿物仿体的包埋位置根据需要进行设置；1. a breast tumor puncture model under ultrasound guidance, is characterized in that, comprises a breast tumor phantom and an embedded phantom, and the breast tumor phantom is arranged in the embedded phantom; the breast tumor phantom Embedding position of the device can be set as required; 所述乳腺肿物仿体的材质与所述包埋仿体的材质相同；所述乳腺肿物仿体的硬度大于所述包埋仿体的硬度。The material of the breast tumor phantom is the same as the material of the embedded phantom; the hardness of the breast tumor phantom is greater than that of the embedded phantom. 2.根据权利要求1所述的超声引导下乳腺肿物穿刺模型，其特征在于，所述乳腺肿物仿体的外表面为光滑外表面或非光滑外表面。2 . The breast tumor puncture model under ultrasound guidance according to claim 1 , wherein the outer surface of the breast tumor phantom is a smooth outer surface or a non-smooth outer surface. 3 . 3.根据权利要求1所述的超声引导下乳腺肿物穿刺模型，其特征在于，所述乳腺肿物仿体的大小及形状相同或不相同。3 . The breast tumor puncture model under ultrasound guidance according to claim 1 , wherein the size and shape of the breast tumor phantom are the same or different. 4 . 4.根据权利要求1所述的超声引导下乳腺肿物穿刺模型，其特征在于，乳腺肿物仿体的颜色与包埋仿体的颜色不同。4 . The ultrasound-guided breast tumor puncture model according to claim 1 , wherein the color of the breast tumor phantom is different from the color of the embedded phantom. 5 . 5.一种上述权利要求1至4中任一项超声引导下乳腺肿物穿刺模型的制备方法，其特征在于，包括乳腺肿物仿体的制备及包埋仿体的制备；5. A method for preparing a breast tumor puncture model under ultrasound guidance in any one of the above claims 1 to 4, characterized in that, comprising the preparation of a breast tumor phantom and the preparation of an embedded phantom; 所述乳腺肿物仿体的制备包括以下步骤：The preparation of the breast tumor phantom comprises the following steps: 1)将PVA粉末倒入去离子水中，不断搅拌至彻底溶解，并将溶液加热至第一设定温度，再加入纤维素并充分搅拌形成悬浊液；1) Pour the PVA powder into deionized water, stir continuously until it is completely dissolved, and heat the solution to the first set temperature, then add cellulose and fully stir to form a suspension; 2)将步骤1)的悬浊液置于冰箱中冷冻第一设定时间后再置于常温下解冻，形成有一定弹性的胶体；2) the suspension of step 1) is placed in a refrigerator to freeze for a first set time and then thawed at normal temperature to form a colloid with certain elasticity; 3)将步骤2)解冻后胶体再次置于冰箱中冷冻所述第一设定时间后再置于常温下解冻；获得乳腺肿物的仿体胶体材料；3) place the colloid after thawing in step 2) in the refrigerator again to freeze the first set time and then place it to thaw at normal temperature; obtain the mimic colloid material of the breast tumor; 4)利用模具制作大小及形状不同的乳腺肿物仿体；4) Use the mold to make breast tumor phantoms of different sizes and shapes; 所述包埋仿体的制备包括以下步骤：The preparation of the embedded phantom comprises the following steps: 5)将PVA粉末倒入去离子水中，不断搅拌至彻底溶解，并将溶液加热至第二设定温度，再加入纤维素并充分搅拌形成悬浊液；5) Pour the PVA powder into deionized water, stir continuously until it is completely dissolved, and heat the solution to the second set temperature, then add cellulose and fully stir to form a suspension; 6)将步骤5)的悬浊液倒入模具中，将步骤4)的乳腺肿物仿体固定于所述模具内的悬浊液中，置于冰箱内冷冻第二设定时间，再置于常温下解冻，制得乳腺肿物穿刺模型。6) Pour the suspension in step 5) into the mold, fix the breast tumor phantom in step 4) in the suspension in the mold, place it in a refrigerator to freeze for a second set time, and place it again. Thaw at room temperature to prepare a breast tumor puncture model. 6.根据权利要求5所述的超声引导下乳腺肿物穿刺模型的制备方法，其特征在于，在步骤1)中还包括添加染色剂。6 . The method for preparing a breast tumor puncture model under ultrasound guidance according to claim 5 , wherein the step 1) further comprises adding a dye. 7 . 7.根据权利要求5所述的超声引导下乳腺肿物穿刺模型的制备方法，其特征在于，在所述步骤2)之前及所述步骤6)之前均包括悬浊液除气步骤。7 . The method for preparing a breast tumor puncture model under ultrasound guidance according to claim 5 , wherein a step of degassing the suspension is included before the step 2) and before the step 6). 8 . 8.根据权利要求5所述的超声引导下乳腺肿物穿刺模型的制备方法，其特征在于，所述第一设定时间与所述第二设定时间相同，均为10-14小时；所述第一设定温度及所述第二设定温度相同均为70℃-90℃。8 . The method for preparing a breast tumor puncture model under ultrasound guidance according to claim 5 , wherein the first set time and the second set time are the same, and both are 10-14 hours; 9 . The first set temperature and the second set temperature are both 70°C-90°C. 9.根据权利要求5所述的超声引导下乳腺肿物穿刺模型的制备方法，其特征在于，包括重复步骤3)一次或一次以上。9 . The method for preparing a breast tumor puncture model under ultrasound guidance according to claim 5 , wherein the method comprises repeating step 3) one or more times. 10 . 10.根据权利要求5所述的超声引导下乳腺肿物穿刺模型的制备方法，其特征在于，所述步骤1)中的PVA用量占悬浊液总重量的5％-20％，纤维素占悬浊液总重量的1％-5％；10. The method for preparing a breast tumor puncture model under ultrasound guidance according to claim 5, wherein the amount of PVA in the step 1) accounts for 5%-20% of the total weight of the suspension, and cellulose accounts for 5%-20% of the total weight of the suspension. 1%-5% of the total weight of the suspension; 所述步骤5)中的PVA用量占悬浊液总重量的5％-20％，纤维素占悬浊液总重量的1％-5％。The amount of PVA in the step 5) accounts for 5%-20% of the total weight of the suspension, and the cellulose accounts for 1%-5% of the total weight of the suspension.
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Cited By (2)

* Cited by examiner, † Cited by third party
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CN110890009A (en) * 2019-12-17 2020-03-17 仲亚东 Mammary gland swelling thing puncture model under ultrasonic guidance
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