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CN109276739A - Absorbent dressing and method for producing same - Google Patents

Absorbent dressing and method for producing same Download PDF

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Publication number
CN109276739A
CN109276739A CN201710594047.9A CN201710594047A CN109276739A CN 109276739 A CN109276739 A CN 109276739A CN 201710594047 A CN201710594047 A CN 201710594047A CN 109276739 A CN109276739 A CN 109276739A
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China
Prior art keywords
mol
foam
prepolymer
dressing
polyethylene glycol
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CN201710594047.9A
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Chinese (zh)
Inventor
朱国栋
蔡坤成
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Taicend International Technology Co ltd
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Taicend International Technology Co ltd
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Priority to CN201710594047.9A priority Critical patent/CN109276739A/en
Publication of CN109276739A publication Critical patent/CN109276739A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/48—Polyethers
    • C08G18/4804—Two or more polyethers of different physical or chemical nature
    • C08G18/4808—Mixtures of two or more polyetherdiols
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/48—Polyethers
    • C08G18/4825—Polyethers containing two hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/48—Polyethers
    • C08G18/4833—Polyethers containing oxyethylene units
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72—Polyisocyanates or polyisothiocyanates
    • C08G18/73—Polyisocyanates or polyisothiocyanates acyclic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/04—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent
    • C08J9/06—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent by a chemical blowing agent
    • C08J9/08—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent by a chemical blowing agent developing carbon dioxide
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2110/00—Foam properties
    • C08G2110/0083—Foam properties prepared using water as the sole blowing agent
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2203/00—Foams characterized by the expanding agent
    • C08J2203/02—CO2-releasing, e.g. NaHCO3 and citric acid
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2203/00—Foams characterized by the expanding agent
    • C08J2203/18—Binary blends of expanding agents

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials For Medical Uses (AREA)

Abstract

本发明公开了一种吸收性敷料及其制造方法。吸收性敷料中包括泡棉敷料层，其底部贴附在皮肤的伤口；以及设置在泡棉敷料层上的聚氨酯膜。吸收性敷料的制造方法包括混合0.5～0.3mol％的聚乙二醇与0.5～0.7mol％的聚丙二醇以形成主剂，加入2.0～2.2mol％硬化剂至主剂以制成预聚物，预聚物的末端具有六亚甲基二异氰酸酯，以及加入功能性添加剂及发泡组合物至预聚物以反应产生泡棉敷料层，以及在泡棉敷料层上形成聚氨酯膜。

The present invention discloses an absorbent dressing and a method for manufacturing the same. The absorbent dressing includes a foam dressing layer, the bottom of which is attached to a wound on the skin; and a polyurethane film disposed on the foam dressing layer. The method for manufacturing the absorbent dressing includes mixing 0.5-0.3 mol% of polyethylene glycol and 0.5-0.7 mol% of polypropylene glycol to form a main agent, adding 2.0-2.2 mol% of a hardener to the main agent to prepare a prepolymer, the end of the prepolymer having hexamethylene diisocyanate, adding a functional additive and a foaming composition to the prepolymer to react to produce a foam dressing layer, and forming a polyurethane film on the foam dressing layer.

Description

Absorbent dressing and its manufacturing method
Technical field
The present invention relates to absorbent dressing technologies, in particular to a kind of with very good moisturizing and soaking effect Absorbent dressing and its manufacturing method.
Background technique
It is well known that traditional technology is simultaneously not added with functionality in the technology of conventional absorbent dressing and its manufacturing method Additive.It is traditionally physical admixture for addition manner, conventional absorbent dressing moistening effect is poor, does not have anti- Bacterium function, therefore urgently improved.
Summary of the invention
In view of this, it is a primary object of the present invention to improve conventional absorbent dressing moistening effect difference and do not have antibacterial The problem of function.
In order to realize above-mentioned purpose and solve the problems, such as, the main purpose of the present invention is to provide a kind of absorbent dressing, It is characterized in that, comprising: foam dressing layer, bottom are attached to the wound of skin；And polyurethane film, it is arranged in foam dressing layer On；Wherein: foam auxiliary material layer is added by functional additive and composition, foam and is formed into prepolymer, the end tool of prepolymer There is hexamethylene diisocyanate, is added by the curing agent hexamethylene diisocyanate of 2.0~2.2mol% to host agent and is reacted It obtains, host agent is made of the polyethylene glycol of 0.5~0.3mol% and the polypropylene glycol of 0.5~0.7mol%.
According to the present invention, in foam auxiliary material layer, when prepolymer is 1.0mol%, preferably composition, foam contains The polyethylene glycol 400 of 0.1~0.3mol%, the water of 0.4~0.6mol%, 0.1mol% sodium bicarbonate, 0.2~0.4mol% Macrogol 600 and 0.01mol% tertiary amine.
In accordance with the present invention it is preferred that the water in the hexamethylene diisocyanate and composition, foam of prepolymer generates two Carbon oxide gas, and then act on and foam with sodium bicarbonate.
In accordance with the present invention it is preferred that functional additive is any one to multiple in sodium hyaluronate, collagen and chitin Kind.
In accordance with the present invention it is preferred that the thickness of polyurethane film is between 0.01~0.04mm, and polyurethane film aqueous vapor is worn Saturating rate is greater than daily 3000 gram/square centimeter.
In accordance with the present invention it is preferred that the thickness of polyurethane film is 0.025mm.
The present invention also provides a kind of preparation methods of above-mentioned absorbability auxiliary material, it is characterised in that: wherein, through mixing The polyethylene glycol of 0.5~0.3mol% and the polypropylene glycol of 0.5~0.7mol% form host agent；It is added 2.0~2.2mol%'s Prepolymer is made to host agent for curing agent, and wherein the end of prepolymer has hexamethylene diisocyanate；Functionality is added to add Agent and composition, foam is added to generate foam dressing layer to prepolymer to react；And polyurethane film is formed, polyurethane film setting exists On foam dressing layer.
According to the present invention, in foam auxiliary material layer, the mol when prepolymer is 1.0mol%, preferably composition, foam contains Have the polyethylene glycol 400 of 0.1~0.3mol%, the water of 0.4~0.6mol%, the sodium bicarbonate of 0.1mol%, 0.2~ The Macrogol 600 of 0.4mol% and the tertiary amine of 0.01mol%.
In accordance with the present invention it is preferred that the water in the hexamethylene diisocyanate and composition, foam of prepolymer generates two Carbon oxide gas, and then act on and foam with sodium bicarbonate.
In accordance with the present invention it is preferred that functional additive is any one to multiple in sodium hyaluronate, collagen and chitin Kind.
The action and effect of invention
The difference of the present invention and traditional technology are: the present invention is added into functional additive, functional additive more It is any in sodium hyaluronate (hyaluronicacid), collagen (collagen) and chitin (chitin/chitosan) One to multiple kind, traditional technology is simultaneously not added with functional additive.In addition, being traditionally physical mixed side for addition manner Formula, addition manner of the invention are to use chemical crosslinking effect, and the molecular weight Mn of foaming body is between 100,000 to 1,000,000.
The advantages of absorbent dressing of the invention is that have very good moisturizing and soaking effect, and soaking effect is to come from PEG400 and PEG600 in the PEG and composition, foam of host agent.Sodium hyaluronate and collagen are that have moisturizing to wound Function, and chitin is that have the function of antibacterial, and the purpose according to absorbent dressing institute expected design to wound, sodium hyaluronate, Both one or any choosing can be arbitrarily selected in collagen and chitin or arbitrarily select three.
Detailed description of the invention
Fig. 1 is the schematic diagram of absorbent dressing of the present invention.
Specific embodiment
As shown in Figure 1, providing the schematic diagram of absorbent dressing by the embodiment of the present invention one, there is bubble in absorbent dressing Cotton dressing layer (foamdressinglayer) 10 is formed with polyurethane film (polyurethanefilm) on foam dressing layer 10 20, the lower surface of foam dressing layer 10 is pasted on the wound 30 of skin 31.
In the present invention, foam dressing layer 10 is first by 0.5~0.3mol% polyethylene glycol (polyethyleneglycol, PEG, Mn2000) and 0.5~0.7mol% polypropylene glycol (polypropyleneglycol, PPG, Ma2000) composed by host agent formed mixture, then with addition 2.0~2.2mol% curing agent hexa-methylene diisocyanate Ester (hexamethylene diisocyanate, HDI) reaction is formed in end, and made prepolymer is added functionality and adds Agent and composition, foam is added to play chemical crosslink reaction and foaming, because the end of prepolymer is hexamethylene diisocyanate, just Generate the foam dressing layer of gas permeability foaming body.
0.1~0.3mol%PEG400 in the case that composition, foam contains relative to 1.0mol% prepolymer, 0.4~ 0.6mol%H2O, 0.1mol%NaHCO3,0.2~0.4mol%PEG600 and catalyst 0.01mol% tertiary amine (tertiaryamines and DBTL).The hexamethylene diisocyanate of prepolymer will after mixing with the water in composition, foam It generates CO2 gas and acts on and foam with saleratus power.
Functional additive is any one to multiple kind in sodium hyaluronate, collagen and chitin.Sodium hyaluronate and collagen egg White is to have the function of moisturizing to wound, and polyethylene glycol and polypropylene glycol are that have the function of water suction to wound, and chitin is Have the function of to wound it is antibacterial, therefore, hexamethylene diisocyanate and PEG and PPG there are also in sodium hyaluronate and collagen- OH base reacts.In the chemical reaction of foaming, saleratus power can with-OH base in sodium hyaluronate and collagen, together with first Shell element-NH2 does chemical crosslinking.These foaming bodies for foaming of chemical crosslinking can be attached on polyurethane film, and pass through traditional object The effect of the additive of reason mixing addition up belongs to different in fact.
The thickness of polyurethane film is between 0.01~0.04mm, is preferred with 0.025mm.Polyurethane film aqueous vapor penetrance MVTR is greater than 3000g/m2.day.Foaming body will generate highly-breathable and high absorbent capacity after being attached on polyurethane film Wound dressing.The function of polyurethane film is to obstruct external bacterium infection, waterproof, antibacterial and regards carrier.
Example A:
Form foam dressing layer, wherein foam dressing layer is first by 0.3mol% polyethylene glycol PEG2000 and 0.1mol% Polyethylene glycol PEG400 and 0.2mol% polyethylene glycol PEG600 and 0.7mol% polypropylene glycol PPG2000 and 0.4mol% water with Host agent composed by 0.1mol%NaHCO3 forms mixture, then uses and 2.2mol% curing agent hexa-methylene diisocyanate is added Ester reaction is formed in end, made prepolymer, be added functional additive and composition, foam rise chemical crosslink reaction and Foaming just generates the foam dressing layer of gas permeability foaming body because the end of prepolymer is hexamethylene diisocyanate；Foam Polyurethane film is formed on dressing layer, the lower surface of foam dressing layer is pasted on the wound of skin.
Example B:
Form foam dressing layer, wherein foam dressing layer is first by 0.4mol% polyethylene glycol PEG2000 and 0.1mol% Polyethylene glycol PEG400 and 0.2mol% polyethylene glycol PEG600 and 0.6mol% polypropylene glycol PPG2000 and 0.4mol% water with Host agent composed by 0.1mol%NaHCO3 forms mixture, then uses and 2.2mol% curing agent hexa-methylene diisocyanate is added Ester reaction is formed in end, made prepolymer, be added functional additive and composition, foam rise chemical crosslink reaction and Foaming just generates the foam dressing layer of gas permeability foaming body because the end of prepolymer is hexamethylene diisocyanate；Foam Polyurethane film is formed on dressing layer, the lower surface of foam dressing layer is pasted on the wound of skin.
Example C:
Form foam dressing layer, wherein foam dressing layer is first by 0.5mol% polyethylene glycol PEG2000 and 0.1mol% Polyethylene glycol PEG400 and 0.2mol% polyethylene glycol PEG600 and 0.5mol% polypropylene glycol PPG2000 and 0.4mol% water with Host agent composed by 0.1mol%NaHCO3 forms mixture, then uses and 2.2mol% curing agent hexa-methylene diisocyanate is added Ester reaction is formed in end, made prepolymer, be added functional additive and composition, foam rise chemical crosslink reaction and Foaming just generates the foam dressing layer of gas permeability foaming body because the end of prepolymer is hexamethylene diisocyanate；Foam Polyurethane film is formed on dressing layer, the lower surface of foam dressing layer is pasted on the wound of skin.
Example D:
Form foam dressing layer, wherein foam dressing layer is first by 0.3mol% polyethylene glycol PEG2000 and 0.1mol% Polyethylene glycol PEG400 and 0.2mol% polyethylene glycol PEG600 and 0.7mol% polypropylene glycol PPG2000 and 0.4mol% water with Host agent composed by 0.1mol%NaHCO3 forms mixture, then uses and 2.2mol% curing agent hexa-methylene diisocyanate is added Ester reaction is formed in end, made prepolymer, be added functional additive and composition, foam rise chemical crosslink reaction and Foaming just generates the foam dressing layer of gas permeability foaming body because the end of prepolymer is hexamethylene diisocyanate；Foam Polyurethane film is formed on dressing layer, the lower surface of foam dressing layer is pasted on the wound of skin.
Example E:
Form foam dressing layer, wherein foam dressing layer is first by 0.3mol% polyethylene glycol PEG2000 and 0.1mol% Polyethylene glycol PEG400 and 0.2mol% polyethylene glycol PEG600 and 0.7mol% polypropylene glycol PPG2000 and 0.4mol% water with Host agent composed by 0.1mol%NaHCO3 and 0.1mol% sodium hyaluronate HA forms mixture, then uses and 2.2mol% hardening is added The reaction of agent hexamethylene diisocyanate is formed in end, and functional additive and foaming combination is added in made prepolymer Object plays chemical crosslink reaction and foaming, because the end of prepolymer is hexamethylene diisocyanate, just generates gas permeability foaming The foam dressing layer of body；Polyurethane film is formed on foam dressing layer, the lower surface of foam dressing layer is pasted to the wound of skin On.
Example F:
Form foam dressing layer, wherein foam dressing layer is first by 0.3mol% polyethylene glycol PEG2000 and 0.1mol% Polyethylene glycol PEG400 and 0.2mol% polyethylene glycol PEG600 and 0.7mol% polypropylene glycol PPG2000 and 0.4mol% water with Host agent composed by 0.1mol%NaHCO3 and 0.2mol% sodium hyaluronate HA forms mixture, then uses and 2.2mol% hardening is added The reaction of agent hexamethylene diisocyanate is formed in end, and functional additive and foaming combination is added in made prepolymer Object plays chemical crosslink reaction and foaming, because the end of prepolymer is hexamethylene diisocyanate, just generates gas permeability foaming The foam dressing layer of body；Polyurethane film is formed on foam dressing layer, the lower surface of foam dressing layer is pasted to the wound of skin On.
The property of foam dressing layer obtained in above-mentioned each example is as shown in the table:
The property for the absorbability auxiliary material layer that one embodiment A-F of table is obtained
The action and effect of embodiment
The difference of the present invention and traditional technology are: the present invention is added into functional additive, functional additive more For any one to multiple kind in sodium hyaluronate, collagen and chitin, traditional technology is simultaneously not added with functional additive.In addition, It is traditionally physical admixture for addition manner, the addition manner of the present invention is to use chemical crosslinking effect, foaming body Molecular weight Mn be between 100,000 to 1,000,000.
The advantages of absorbent dressing of the invention is that have very good moisturizing and soaking effect, and soaking effect is to come from PEG400 and PEG600 in the PEG and composition, foam of host agent.Sodium hyaluronate and collagen are that have moisturizing to wound Function, and chitin is that have the function of antibacterial, and the purpose according to absorbent dressing institute expected design to wound, sodium hyaluronate, Both one or any choosing can be arbitrarily selected in collagen and chitin or arbitrarily select three.
Above embodiments are only to express preferred embodiment of the invention, and but it cannot be understood as to this The limitation of invention claim.It should be pointed out that not departing from this for those skilled in the art in the art Under the premise of inventive concept, complex deformation and improvement can also be made, these are all within the scope of protection of the present invention.
Above embodiment is preferred case of the invention, the protection scope being not intended to limit the invention.

Claims (10)

1.一种吸收性敷料，其特征在于，包括：1. An absorbent dressing, characterized in that, comprising: 泡棉敷料层，底部用于贴附在皮肤的伤口；以及a layer of foam dressing, the bottom of which is used to adhere to the wound on the skin; and 聚氨酯膜，设置在所述泡棉敷料层上；a polyurethane film, arranged on the foam dressing layer; 其中：in: 所述泡棉辅料层是由功能性添加剂及发泡组合物加入至预聚物中组成，The foam auxiliary material layer is composed of functional additives and foaming compositions added to the prepolymer, 所述预聚物是由2.0～2.2mol％的硬化剂六亚甲基二异氰酸酯加入至主剂反应得到的，其末端具有六亚甲基二异氰酸酯，The prepolymer is obtained by adding 2.0-2.2 mol% of hardener hexamethylene diisocyanate to the main agent for reaction, and its end has hexamethylene diisocyanate, 所述主剂由0.5～0.3mol％的聚乙二醇与0.5～0.7mol％的聚丙二醇组成的。The main agent is composed of 0.5-0.3 mol% polyethylene glycol and 0.5-0.7 mol% polypropylene glycol. 2.根据权利要求1所述吸收性敷料，其特征在于：2. The absorbent dressing of claim 1, wherein: 其中，在所述泡棉辅料层中，当所述预聚物为1.0mol％时，所述发泡组合物含有0.1～0.3mol％的聚乙二醇400、0.4～0.6mol％的水、0.1mol％的碳酸氢钠、0.2～0.4mol％的聚乙二醇600以及0.01mol％的三级胺。Wherein, in the foam auxiliary material layer, when the prepolymer is 1.0 mol%, the foaming composition contains 0.1-0.3 mol% of polyethylene glycol 400, 0.4-0.6 mol% of water, 0.1 mol% of sodium bicarbonate, 0.2 to 0.4 mol% of polyethylene glycol 600 and 0.01 mol% of tertiary amine. 3.根据权利要求2所述吸收性敷料，其特征在于：3. The absorbent dressing of claim 2, wherein: 其中，所述预聚物的六亚甲基二异氰酸酯与所述发泡组合物中的水产生二氧化碳气体，进而与所述碳酸氢钠作用而发泡。Wherein, the hexamethylene diisocyanate of the prepolymer and the water in the foaming composition generate carbon dioxide gas, which further reacts with the sodium bicarbonate to foam. 4.根据权利要求1所述吸收性敷料，其特征在于：4. The absorbent dressing of claim 1, wherein: 其中，所述功能性添加剂为玻尿酸、胶原蛋白及甲壳素中的任意一至多种。Wherein, the functional additive is any one or more of hyaluronic acid, collagen and chitin. 5.根据权利要求1所述吸收性敷料，其特征在于：5. The absorbent dressing of claim 1, wherein: 其中，所述聚氨酯膜的厚度是在0.01～0.04mm之间，且所述聚氨酯膜水气穿透率大于每日3000克/平方公尺。Wherein, the thickness of the polyurethane film is between 0.01 and 0.04 mm, and the water vapor transmission rate of the polyurethane film is greater than 3000 g/m2 per day. 6.根据权利要求5所述吸收性敷料，其特征在于：6. The absorbent dressing of claim 5, wherein: 其中，所述聚氨酯膜的厚度是0.025mm。Wherein, the thickness of the polyurethane film is 0.025mm. 7.一种吸收性敷料的制造方法，其特征在于，包括：7. A method for manufacturing an absorbent dressing, comprising: 混合0.5～0.3mol％的聚乙二醇与0.5～0.7mol％的聚丙二醇以形成主剂；mixing 0.5-0.3 mol% of polyethylene glycol and 0.5-0.7 mol% of polypropylene glycol to form a main agent; 加入2.0～2.2mol％硬化剂六亚甲基二异氰酸酯至所述主剂反应以制成预聚物，其中所述预聚物的末端具有六亚甲基二异氰酸酯；adding 2.0-2.2 mol% hardener hexamethylene diisocyanate to the main agent to react to prepare a prepolymer, wherein the end of the prepolymer has hexamethylene diisocyanate; 加入功能性添加剂及发泡组合物以反应产生所述泡棉敷料层；以及adding functional additives and a foaming composition to react to produce the foam dressing layer; and 在所述泡棉敷料层上形成聚氨酯膜，其中所述泡棉敷料层的底部用于贴附至皮肤的伤口。A polyurethane film is formed on the foam dressing layer, wherein the bottom of the foam dressing layer is used to adhere to the wound of the skin. 8.根据权利要求7所述吸收性敷料的制造方法，其特征在于：8. The manufacturing method of the absorbent dressing according to claim 7, wherein: 其中，所述功能性添加剂为玻尿酸、胶原蛋白及甲壳素中的任意一至多种。Wherein, the functional additive is any one or more of hyaluronic acid, collagen and chitin. 9.根据权利要求7所述吸收性敷料的制造方法，其特征在于：9. The manufacturing method of the absorbent dressing according to claim 7, characterized in that: 其中，在所述泡棉辅料层中，当所述预聚物为1.0mol％时，所述发泡组合物含有0.1～0.3mol％的聚乙二醇400、0.4～0.6mol％的水、0.1mol％的碳酸氢钠、0.2～0.4mol％的聚乙二醇600以及0.01mol％的三级胺。Wherein, in the foam auxiliary material layer, when the prepolymer is 1.0 mol%, the foaming composition contains 0.1-0.3 mol% of polyethylene glycol 400, 0.4-0.6 mol% of water, 0.1 mol% of sodium bicarbonate, 0.2 to 0.4 mol% of polyethylene glycol 600 and 0.01 mol% of tertiary amine. 10.根据权利要求8所述吸收性敷料的制造方法，其特征在于：10. The manufacturing method of the absorbent dressing according to claim 8, characterized in that: 其中，所述预聚物的六亚甲基二异氰酸酯与所述发泡组合物中的水产生二氧化碳气体，进而与碳酸氢钠作用而发泡。Wherein, the hexamethylene diisocyanate of the prepolymer and the water in the foaming composition generate carbon dioxide gas, and then react with sodium bicarbonate to foam.
CN201710594047.9A 2017-07-20 2017-07-20 Absorbent dressing and method for producing same Pending CN109276739A (en)

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