CN109011161A - A kind of reverse winding and its design method for transcranial magnetic stimulation - Google Patents
A kind of reverse winding and its design method for transcranial magnetic stimulation Download PDFInfo
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- CN109011161A CN109011161A CN201811008873.1A CN201811008873A CN109011161A CN 109011161 A CN109011161 A CN 109011161A CN 201811008873 A CN201811008873 A CN 201811008873A CN 109011161 A CN109011161 A CN 109011161A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/004—Magnetotherapy specially adapted for a specific therapy
- A61N2/006—Magnetotherapy specially adapted for a specific therapy for magnetic stimulation of nerve tissue
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/02—Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
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Abstract
The present invention proposes that a kind of reverse winding for transcranial magnetic stimulation, the coil are located above splayed coil, are spatially overlapped with splayed hub of a spool.The electric current of the every side circular coil of reverse winding and ipsilateral splayed coil circular coil current direction are on the contrary, make the direction of an electric field of reverse winding generation with splayed coil direction of an electric field on the contrary, so as to effectively reduce the electric field strength at scalp.The angle of this reverse winding is variable, the alterable height apart from above-head.By the angle, height and the inner and outer diameter that change reverse winding, thus it is possible to vary to the size of attenuation at scalp, while improving the focusing of splayed coil.
Description
Technical field
The invention belongs to can subtract while a kind of transcranial magnetic stimulation field, in particular to raising splayed coil focusing
The design of the reverse winding of electric field strength at weak scalp.
Background technique
Transcranial magnetic stimulation (Transcranial magnetic stimulation, TMS) is a kind of noninvasive painless green
Treatment technology.The stimulating coil for being placed on above-head generates changing magnetic field, and by electromagnetic induction, changing magnetic field generates sense
Electric field is answered, stimulates cerebral nerve to reach therapeutic purposes.In transcranial magnetic stimulation, accurately to be stimulated, the electricity of coil generation
Magnetic field strength, stimulation depth and focusing require to reach certain requirement.
Compared to circular coil, the focusing of splayed coil increases, but field stimulation is larger, and specific aim is not strong,
It can not achieve good focusing.Chinese invention patent " double butterfly transcranial magnetic stimulation coil " (application number: 201210210607.3)
It is related to a kind of cerebral magnetic stimulation coil of double splayed structures, by increasing a pair of more minor radius in traditional splayed coil
Splayed coil improves the focusing of traditional splayed coil.Chinese invention patent is " for the more of deep position transcranial magnetic stimulation
(application number: 201510398375.2) using multi-tier arrangement coil to the eccentric figure-eight coil of layer ", and first layer is basic splayed line
Circle, below each layer line circle it is symmetrical along splayed coil centerline, for adjusting magnetic field and induction field reaches good poly-
Focal power.Chinese invention patent " a kind of for four loop constructions of transcranial magnetic stimulation and its application " (application number:
201710817412.8) it is related to a kind of four coil transcranial magnetic stimulation invention devices, which can be to multiple positions of human brain
Neural stem cell focus stimulates simultaneously, meets complicated stimulation needs.
Above-mentioned patent improves focusing using different stimulated coil, in clinical application, when electric current is larger in stimulating coil
When scalp at will generate biggish electromagnetic field intensity, make to generate at patient's scalp to some extent uncomfortable.Thus it is guaranteed that coil has
While having more preferable focusing, it is also desirable to reduce the electric field strength at scalp.
Summary of the invention
It is an object of that present invention to provide a kind of novel cerebral magnetic stimulation coils for being referred to as reverse winding.Based on splayed line
Circle, increases reverse winding above it, the focusing of splayed coil can be improved, while reducing electric field strength at scalp, increases
Add the stimulation depth of splayed coil.
The present invention adopts the following technical scheme:
Reverse winding for transcranial magnetic stimulation is placed in above splayed coil, is made of two circular coils, and reversed
The angle and alterable height of coil.
Round coil current is that clockwise, right side circle coil current is counterclockwise on the left of reverse winding.Eight
Round coil current is that counterclockwise, right side circle coil current is clockwise on the left of font coil.That is reverse winding
Two circular coil current directions it is opposite with the circular coil current direction that splayed coil is ipsilateral.
Height of the two circular coil crosspoints of reverse winding apart from head the top is 20-55mm, is spaced 5mm.
Folder when height of the reverse winding apart from above-head is 40-55mm, between two circular coils of reverse winding
Angular region is 90 ° -180 °；When reverse winding height is 30-35mm, the angular range between two circular coils is 120 ° -180 °；
When reverse winding height is 20-25mm, the angular range between two circular coils is 150 ° -180 °.
Reverse winding has following four kinds of sizes: (1) interior diameter is 15mm, overall diameter 46mm；(2) interior diameter is 25mm,
Overall diameter is 56mm；(3) interior diameter of coil is 35mm, overall diameter 66mm；(4) interior diameter of coil is 45mm, overall diameter
For 76mm.
Splayed the coil side of being positioned on the head 5mm, interior diameter 56mm, overall diameter 87mm below reverse winding.
Compared with prior art, the invention has the following advantages that the current direction of the every side circular coil of reverse winding with
Ipsilateral splayed coil circular coil current direction is on the contrary, what the electric field strength and splayed coil that generate reverse winding generated
Electric field strength is contrary,, can be with by changing the height of reverse winding since reverse winding is always above splayed coil
The electric field strength at scalp is reduced to some extent, and changes the stimulation depth of coil.Simultaneously by changing reverse winding
Angle, thus it is possible to vary the focusing of coil.Therefore, the suitable height of reverse winding selection and angle can reach decrease head simultaneously
Electric field strength, increase stimulation depth at skin and the effect for improving coil focusing.
Detailed description of the invention
Fig. 1 is reverse winding and splayed coil former schematic diagram.
Fig. 2 is reverse winding, splayed coil and true head model schematic.α indicates two circular coil of reverse winding
Between angle, H indicates height of the intersection point apart from above-head of two circular coil of reverse winding.
Fig. 3 is the histogram of electric field slip at different height and the reverse winding scalp of angle.
Fig. 4 is the relational graph of electric field slip at the reverse winding stimulation depth and scalp of different height and angle.
Fig. 5 is the relational graph of electric field slip at different height and the reverse winding focal area and scalp of angle.
Fig. 6 be splayed coil (a) and various sizes of reverse winding (b)-(c) (average diameter is respectively 30mm,
40mm, 50mm and 60mm) electric-field intensity distribution figure at scalp.Using normalized splayed coil electric field strength as standard.
Fig. 7 is that electric field is reduced at stimulation depth, focal area and the scalp of splayed coil and different size reverse windings
Rate three-dimensional scatter plot.
Specific embodiment
Transcranial magnetic stimulation reverse winding of the invention is described in further detail in conjunction with attached drawing.
The splayed coil that the present invention uses for Magstim company's T ype 9925, coil inner and outer diameter be respectively 56mm and
87mm, the side of being positioned on the head 5mm.Reverse winding inner and outer diameter is respectively 25mm and 56mm.Splayed coil and reverse winding around
Group is formed by copper wire winding, and cross-sectional area is 6mm × 1.75mm, and coil turn is 9 circles.
Splayed coil and reverse winding structure and current direction schematic diagram are as shown in Figure 1.Reverse winding is by two circles
Coil composition, angle and alterable height.Reverse winding is located above splayed coil, spatially with splayed hub of a spool weight
It closes.Round coil current is that clockwise, right side circle coil current is counterclockwise on the left of reverse winding.Splayed line
The round coil current in circle left side is that counterclockwise, right side circle coil current is clockwise.I.e. ipsilateral circular coil
Current direction is opposite.
Fig. 2 is reverse winding, splayed coil and true head model schematic.α indicates two circular coil of reverse winding
Between angle, H indicates height of the intersection point apart from above-head of two circular coil of reverse winding.Reverse winding shown in Fig. 2
Height is 55mm, and angle is 120 °.The altitude range of reverse winding is 20-55mm in the present invention, is spaced 5mm.Work as reverse winding
When height is 40-55mm, reverse winding angular range is 90 ° -180 °.When reverse winding height is 30mm-35mm, reverse line
Enclosing angular range is 120 ° -180 °.When height is 20mm-25mm, reverse winding angular range is 150 ° -180 °.
To obtain the optimum height and angle of reverse winding, embodiment are as follows: reverse winding interior diameter 25mm, overall diameter
56mm is invariable, emulates to the reverse winding of different height and angle, analyzes electricity at more each reverse winding scalp
Slip, stimulation depth and focusing performance formulate evaluation criterion and carry out overall merit, obtain reverse winding optimum height and
Best angle.For the power that the electric field strength that more each reverse winding generates acts on reduction at scalp, electricity at scalp is defined
Field intensity slip are as follows:
Wherein E8maxIndicate the maximum value for the electric field strength that splayed coil generates at scalp, ERmaxIndicate reverse winding
The maximum value of the electric field strength generated at scalp with splayed coil.The electric field strength that reverse winding generates at scalp is got over
Small, β value is bigger, illustrate reverse winding than splayed coil at scalp electric field strength reduce it is more, reverse winding to scalp at
Electric field strength reduction effect it is better.Electric field strength slip is as shown in Figure 3 at different height and angle reverse winding scalp.From
The height that the histogram can be seen that reverse winding is smaller, and electric field strength slip is bigger at scalp.When height is identical, instead
Smaller to coil angle, electric field slip is bigger at scalp.It can thus be concluded that the slip of reverse winding and the height of reverse winding
It is inversely proportional, it is directly proportional to the corner dimension of reverse winding.
Fig. 4 is the relationship at each reverse winding stimulation depth and scalp between electric field strength slip.It defines from scalp
Surface field maximum value drops to the distance of maximum value half to electric field strength as stimulation depth depth (E=Emax/2).It is different
Point indicate different height and angle reverse winding.The stimulation depth of reverse winding is reduced with electric field at scalp as shown in Figure 4
Rate is directly proportional, i.e., the reverse winding stimulation depth that electric field strength slip is big at scalp is big, illustrates the attenuation of reverse winding
It is good.
Fig. 5 is the relationship at focal area and scalp between electric field strength slip.Focal area is defined as electric field strength
More than the area of maximum value half at scalp.Different points indicates the reverse winding of different height and angle.It is reversed as shown in Figure 5
Coil focal area is directly proportional to electric field strength slip at scalp, illustrates that electric field is reduced at the focusing and scalp of reverse winding
Rate is inversely proportional, i.e. reverse winding is bigger to the electric field strength slip at scalp, and the focal area of coil is bigger, the focusing of coil
Property is poorer, to illustrate that the stimulation depth of coil is difficult to reach consistent effect with focusing.
For the reverse winding for selecting optimum height and angle, can have simultaneously preferable focusing, stimulation depth and
Slip at higher scalp establishes following evaluation criterion: (1) slip of reverse winding is 15% or more；(2) reverse winding
Stimulation depth be greater than splayed coil stimulation depth；(3) focal area of reverse winding is less than splayed coil focusing surface
Long-pending 2 times.Meet there are five types of all reverse windings of three conditions, their height and angle is respectively as follows: (1) H=20mm, α
=180 °；(2) H=25mm, α=180 °；(3) H=30mm, α=150 °；(4) H=35mm, α=150 °；(5) H=35mm, α
=120 °.It is full when the focal area that third condition is reduced into reverse winding is less than 1.5 times of splayed coil focal area
The height and angle of the reverse winding of sufficient condition are H=30mm, α=150 °.It is to obtain the optimum height of reverse winding
30mm, optimum angle are 150 °.
It is to obtain the optimum size of reverse winding under optimum condition in the height and angle of reverse winding.Embodiment are as follows:
Establish three kinds of new reverse windings: (1) interior diameter is 15mm, overall diameter 46mm；(2) interior diameter is 35mm, and overall diameter is
66mm；(3) interior diameter is 45mm, overall diameter 76mm.Reverse winding interior diameter in above-mentioned analysis is 25mm, and overall diameter is
56mm.Splayed coil in the present invention is 9925 type coil of Type that Magstim company proposes.Its interior diameter is 56mm, outside
Diameter is 87mm.Analysis comparison is carried out to above-mentioned five kinds of coils respectively.Electric-field intensity distribution of five kinds of coil formers at scalp
As a result as shown in Figure 6.Using the normalized electric field intensity value of splayed coil as standard.Stimulating coil is splayed as shown in Figure 6
Electric field strength is maximum at scalp when coil, and after increasing reverse winding, reverse winding diameter is bigger, and electric field strength is smaller at scalp,
It is bigger to the attenuation at scalp.
Fig. 7 show the three-dimensional scatterplot of electric field strength slip at stimulation depth, focal area and the scalp of different coils
Figure.Different points indicates splayed coil and various sizes of reverse winding.R indicates the average diameter of each reverse winding.It is interior
Diameter is 15mm, and overall diameter is the reverse winding of 46mm, and average diameter 30mm is denoted as R=30mm.Similarly, interior diameter is
25mm, overall diameter 56mm；Interior diameter is 35mm, and overall diameter is 66mm and interior diameter is 45mm, and overall diameter is the reversed of 76mm
Coil, average diameter is respectively 40mm, 50mm and 60mm, therefore is denoted as R=40mm, R=50mm and R=60mm respectively.Figure
In three coordinate values representing of each point be respectively to stimulate depth, the electric field slip at focal area and scalp.With reversed
The size of coil increases, and focal area is gradually reduced, and illustrates that the increase of coil dimension can effectively improve the focusing of coil.
When the average diameter of reverse winding is 60mm, electric field strength slip is most compared with other sizes reverse winding, at scalp
Greatly, stimulation depth and splayed coil stimulation depth are close, and focal area reaches minimum, it is seen that its comprehensive performance is best.Due to
The constraint of height and angle by reverse winding, the size of reverse winding cannot increase again, therefore average diameter is 60mm,
I.e. interior diameter is 45mm, and overall diameter is the optimum size that 76mm is reverse winding.
Compared by above-mentioned analysis, finally show that angle is 150 °, and interior diameter is when the height of reverse winding is 30mm
45mm, when overall diameter is 76mm, focal area reaches minimum, is the 68.7% of splayed coil focal area, at scalp
Electric field strength slip is maximum, is 34.55%, and stimulation depth is to stimulate depth to increase 1.6% than splayed coil, the reverse line
The comprehensive performance of circle is best.
Claims (5)
1. a kind of reverse winding for transcranial magnetic stimulation, which is characterized in that the reverse winding is made of two circular coils, instead
To the angle and alterable height of coil；Reverse winding is placed in above splayed coil.
2. reverse winding according to claim 1, which is characterized in that round coil current is clockwise on the left of reverse winding
Direction, right side circle coil current are counterclockwise.Round coil current is counterclockwise right side on the left of splayed coil
Circular coil electric current is clockwise.That is two circular coil current directions of reverse winding and the ipsilateral circle of splayed coil
The direction of the winding current is opposite.
3. reverse winding according to claim 1, which is characterized in that two circular coil crosspoints of reverse winding are apart from head
The altitude range of portion the top is 20-55mm, is spaced 5mm.
4. reverse winding according to claim 1, which is characterized in that when reverse winding is 40- apart from above-head height
When 55mm, the angular range between two circular coils of reverse winding is 90 ° -180 °；When reverse winding height is 30-35mm,
Angular range between two circular coils is 120 ° -180 °；When height is 20-25mm, angular range is 150 ° -180 °.
5. reverse winding according to claim 1, which is characterized in that the reverse winding has following four kinds of sizes: (1) straight in
Diameter is 15mm, overall diameter 46mm；(2) interior diameter is 25mm, overall diameter 56mm；(3) interior diameter is 35mm, and overall diameter is
66mm；(4) interior diameter is 45mm, overall diameter 76mm.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811008873.1A CN109011161A (en) | 2018-08-31 | 2018-08-31 | A kind of reverse winding and its design method for transcranial magnetic stimulation |
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| CN201811008873.1A CN109011161A (en) | 2018-08-31 | 2018-08-31 | A kind of reverse winding and its design method for transcranial magnetic stimulation |
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Cited By (3)
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| CN109621209A (en) * | 2018-12-29 | 2019-04-16 | 北京神畅科技发展有限公司 | A kind of inside and outside reversal circle cerebral magnetic stimulation coil |
| CN113440731A (en) * | 2021-08-11 | 2021-09-28 | 成都理工大学 | Asymmetric special-shaped coil for craniocerebral electromagnetic stimulation and craniocerebral electromagnetic stimulation system |
| CN114191720A (en) * | 2021-12-20 | 2022-03-18 | 天津工业大学 | Cross coil for deep transcranial magnetic stimulation |
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| CN114191720A (en) * | 2021-12-20 | 2022-03-18 | 天津工业大学 | Cross coil for deep transcranial magnetic stimulation |
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Application publication date: 20181218 |