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CN108836901A - A kind of facial mask essence of the Product filtrate containing saccharomycetes to make fermentation and preparation method thereof - Google Patents

A kind of facial mask essence of the Product filtrate containing saccharomycetes to make fermentation and preparation method thereof Download PDF

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Publication number
CN108836901A
CN108836901A CN201811123218.0A CN201811123218A CN108836901A CN 108836901 A CN108836901 A CN 108836901A CN 201811123218 A CN201811123218 A CN 201811123218A CN 108836901 A CN108836901 A CN 108836901A
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China
Prior art keywords
saccharomycetes
make fermentation
glycol
facial mask
hexylene glycol
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Pending
Application number
CN201811123218.0A
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Chinese (zh)
Inventor
林国华
林靖杰
黄文�
樊锋凯
胡思
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Chang'e Innovation (wuhan) Biotechnology Co Ltd
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Chang'e Innovation (wuhan) Biotechnology Co Ltd
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Priority to CN201811123218.0A priority Critical patent/CN108836901A/en
Publication of CN108836901A publication Critical patent/CN108836901A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30Characterized by the absence of a particular group of ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of maintenance anti-ageing face mask Essences and preparation method thereof, and facial mask essence includes:The golden yellow camomile extract of 0.1%-2% Sodium Hyaluronate, 0.01-1%, 0.1-4% beta glucan, 2-10% propylene glycol, 0.5-4% butanediol, 0.1-3% acrylic acid/MA copolymer sodium, 2-10% glycerol, 0.05-0.5% saccharomycetes to make fermentation Product filtrate, 0.1-0.5%N15 polypeptide, 0.8-1.5% oligopeptides -1,0.2-6%1,2- hexylene glycol, 0.2-8%1,3-propanediol, 0.3-6%1, the pungent glycol of 6- hexylene glycol, 0.1-3%, 0.01-0.15% decoyl hydroximic acid and 0.1-5% hexylene glycol, surplus are water.The present invention combines the active skull cap components such as saccharomycetes to make fermentation Product filtrate and N15 polypeptide, develop the skin-protection product with maintenance anti-aging effects, greatly improve the transdermal absorption factor of active constituent, enrich product efficacy, essence, alcohol and preservative are not added simultaneously, ensure the mild muting sensitive of facial mask essence, reduces the stimulation to skin.Preparation process is simple simultaneously, and reaction condition is mild, and raw material is cheap to be easy to get, and greatly reduces cost of manufacture.

Description

A kind of facial mask essence of the Product filtrate containing saccharomycetes to make fermentation and preparation method thereof
Technical field
The present invention relates to daily cosmetics fields, particularly relate to a kind of facial mask of Product filtrate containing saccharomycetes to make fermentation Essence and preparation method thereof.
Background technique
Skin is the maximum organ of human body, not only protect human body from external injury and stimulation, can also prevent internal water, The loss of nutriment etc.;Due to human skin direct long term contact environmental stimuli, skin barrier is easy to be damaged, and causes skin Dry relaxation, fragile sensitive and inflammatory reaction.Existing common skin care item focus mostly in replenishing water and preserving moisture effect, there is part publicity Functional skin care item add some macromolecule nutritional agents, even hormones on the basis of common skin care item, allow consumer to generate and beautify Dependence, injure consumer's body and mind.And facial mask can support in a short time for skin injection as the cosmetics and skincare product applied on the face Point, play the role of cleaning, maintenance face, therefore popular among consumers.
Saccharomycete is earliest by the widely applied microorganism of the mankind.Before 8000, Chaldaic and Greece women Wound healing is helped, wash one's face and is wiped body with the foam that saccharomyces cerevisiae and its fermentation generate.But yeast extract skin care Product have the following problems when highly sought:1. yeast is biologically active microorganism, it is added directly into meeting in skin care item Cause microorganism to severely exceed, destroys skin and body.2. existing leading viable yeast class skin care item, often declare " viable yeast ", Possess powerful maintenance and tough effect, complicated component, effect actually is single, it is difficult to meet maintenance skin barrier, whitening and anti-aging Equal multi-efficiencies.
Saccharomycetes to make fermentation Product filtrate is the active matter extracted from yeast, rich in protein, polypeptide, amino acid, dimension life More than the 50 kinds of natural nutrient substances such as plain B, minerals, immune polysaccharide, and contain various bioactivators, it can smash pigment Group, uniform skin color have skin-active, function of delaying senility.Its powerful antioxygenic property helps skin to resist freedom simultaneously The infringement of base, defence skin surface is impaired, allows the tender brilliant white of skin, realizes persistently fair and clear, flawless.It is mainly sent out at present with saccharomycete The forms such as zymotic fluid are applied to the fields such as cosmetics.Such as the patent of Publication No. CN105055296A《One kind containing saccharomycetes to make fermentation The composite skin care product of Product filtrate》, publication number CN108066172A patent《TIA yeast peptide tunning filtrate preparation side Method and its functional application in skin-whitening and speckle eliminating》, publication number CN108096081A patent《One primary yeast extractive from fermentative Composition and its application in cosmetics》, publication number CN105434323A patent《Saccharomycetes to make fermentation compound and its Application in skin whitening, moisturizing skin care item》Deng.
The present invention regard saccharomycetes to make fermentation Product filtrate, N15 polypeptide etc. as main effective component, by matching to skin care item The improvement of side, obtain it is a kind of can significantly repair damaged cell, cell nutrients are replenished in time, conditioning and remolds skin consolidation at problem flesh The sliding facial mask essence of children.
Summary of the invention
To solve the problems mentioned above in the background art, the purpose of the present invention is to provide one kind to produce containing saccharomycetes to make fermentation The facial mask essence and preparation method thereof of object filtrate.
To achieve the above object, the technical scheme adopted by the invention is as follows:
The present invention provides a kind of facial mask essences of Product filtrate containing saccharomycetes to make fermentation, including following mass percents Ingredient:
The golden yellow camomile extract of 0.1%-2% Sodium Hyaluronate, 0.01-1%, 0.1-4% beta glucan, 2-10% third Glycol, 0.5-4% butanediol, 0.1-3% acrylic acid/MA copolymer sodium, 2-10% glycerol, 0.05-0.5% saccharomycetes to make fermentation produce Object filtrate, 0.01-0.05%N15 polypeptide, 0.8-1.5% oligopeptides -1,0.2-6%1,2- hexylene glycol, 0.2-8%1,3- the third two Alcohol, 0.3-6%1, the pungent glycol of 6- hexylene glycol, 0.1-3%, 0.01-0.15% decoyl hydroximic acid and 0.1-5% hexylene glycol, surplus For water.
Further, the facial mask essence of a kind of Product filtrate containing saccharomycetes to make fermentation, including following mass percents at Point:0.5% Sodium Hyaluronate, 0.1% golden yellow camomile extract, 2.5% beta glucan, 4% propylene glycol, 2% butanediol, 2.5% acrylic acid/MA copolymer sodium, 5% glycerol, 0.45% saccharomycetes to make fermentation Product filtrate, 0.025%N15 polypeptide, 1% widow Peptide -1,4%1,2- hexylene glycol, 5%1,3- propylene glycol, 4%1,6- hexylene glycol, 2% pungent glycol, 0.1% decoyl hydroximic acid and 4% Hexylene glycol, surplus are water.
Further, the facial mask essence of the resulting Product filtrate containing saccharomycetes to make fermentation is the transparent clarified solution of colorless and odorless Body.
Further, the glycerol is De-Nol USP United States Pharmacopeia grade pure glycerin.
Further, the preparation method of the facial mask essence of the Product filtrate containing saccharomycetes to make fermentation, it is characterised in that: Include the following steps:
1) component A liquid:The golden yellow camomile extract of 0.1%-2% Sodium Hyaluronate, 0.01-1%, 0.1-4% β-Portugal are poly- Sugar, 2-10% propylene glycol, 0.5-4% butanediol, 0.1-3% acrylic acid/MA copolymer sodium and 2-10% glycerol, surplus are water.
2) component B liquid:0.05-0.5% saccharomycetes to make fermentation Product filtrate, 0.8-1.5% oligopeptides -1,0.2-6%1,2- oneself Glycol, 0.2-8%1,3- propylene glycol, 0.3-6%1,6- hexylene glycol, the pungent glycol of 0.1-3%, 0.01-0.15% decoyl hydroximic acid With 0.1-5% hexylene glycol;
3) production equipment used is cleaned up, is disinfected, for use;
4) step 1) obtained component A liquid is added in ingredients pot, opens homogenizer, homogeneous is heated to grainless object After 80-85 DEG C, speed of agitator 35r/min, heat preservation 30 minutes, each ingredient in component A liquid is sufficiently dissolved;
5) when the resulting mixed solution temperature of step 4) is down to 42 DEG C, step 2) obtained component B liquid is added, unlatching is stirred It mixes, mixing speed 30r/min, stirs 20 minutes.
6) when the resulting mixed solution temperature of step 5) is down to 38 DEG C, sampling send laboratory to detect, and filters out after qualified Material, stand to get maintenance anti-aging facial mask essence.
In the present invention, saccharomycetes to make fermentation Product filtrate, which has, improves skin blood circulation and metabolism, makes skin tender Saccharomycetes to make fermentation Product filtrate can be enhanced N15 polypeptide with the combination of N15 polypeptide and repaired to releiving for skin by skin-active effect of brilliant white Shield, anti-aging effect.
Sodium Hyaluronate, as ideal natural moisturizing factor, compatibility is good, can open corium moisturizing channel, seeps and reaches flesh Bottom improves skin-nourishing metabolism, and skin is made to keep elasticity, and epidermal tissue is repaired in help, to have maintenance, senile-resistant efficacy.
Oligopeptides -1, i.e. epidermal growth factor EGF are a kind of small active peptides, can promote basal cell proliferation, differentiation, A large amount of to generate neonatal cell, delay skin aging makes skin keep best physiological status, while can fill epidermal cell, stimulation Synthesis, the secretion of extracellular hyaluronic acid and collagen, repair the collagen elastomer of aging fracture, to play anti-aging Effect.
Golden yellow camomile extract has inhibiting effect to the inductivity allergy of skin;The resistance of capillary can be enhanced, Free radical can be eliminated simultaneously, it is anti-oxidant, have and alleviates aging effect.
Compared with prior art, the beneficial effects of the invention are as follows:
1, the present invention combines the active skull cap components such as saccharomycetes to make fermentation Product filtrate and N15 polypeptide, develops Skin-protection product with maintenance anti-aging effects greatly improves the transdermal absorption factor of active constituent, enriches product efficacy, simultaneously Essence, alcohol and preservative are not added, it is ensured that the mild muting sensitive of facial mask essence reduces the stimulation to skin.
2, the facial mask essence of the Product filtrate containing saccharomycetes to make fermentation is filled using individual packets, light and handy portable, product safety temperature With it is non-stimulated, ingredient is simple, and long-time service will not generate dependence, and ductility is good, cold and hot excellent in stability.
A kind of facial mask essence and preparation method thereof of Product filtrate containing saccharomycetes to make fermentation provided by the invention, gained maintenance Anti-ageing face mask Essence, which can be used for preparing, has effects that drug or cosmetics that anti-ageing compact maintenance is releived, avoids using chemistry Whitening agent and plant extract agent are caused harm to the human body and are stimulated, the disadvantage of stability difference for skin whitening, are prepared simultaneously Method and process process is simple, and reaction condition is mild, and raw material is cheap to be easy to get, and greatly reduces cost of manufacture.
Detailed description of the invention
Fig. 1 is that maintenance anti-ageing face mask Essence provided by the invention changes bar shaped before and using each index of rear skin Figure.
Specific embodiment
To be easy to understand the technical means, the creative features, the aims and the efficiencies achieved by the present invention, below with reference to The drawings and specific embodiments, how the present invention is further explained implements.
The present invention provides a kind of facial mask essences of Product filtrate containing saccharomycetes to make fermentation, including following mass percents Ingredient:The golden yellow camomile extract of 0.1%-2% Sodium Hyaluronate, 0.01-1%, 0.1-4% beta glucan, 2-10% the third two Alcohol, 0.5-4% butanediol, 0.1-3% acrylic acid/MA copolymer sodium, 2-10% glycerol, 0.05-0.5% saccharomycetes to make fermentation product Filtrate, 0.01-0.05%N15 polypeptide, 0.8-1.5% oligopeptides -1,0.2-6%1,2- hexylene glycol, 0.2-8%1,3- propylene glycol, The pungent glycol of 0.3-6%1,6- hexylene glycol, 0.1-3%, 0.01-0.15% decoyl hydroximic acid and 0.1-5% hexylene glycol, surplus are Water.
N15 polypeptide sequence in the present invention is:Met-Pro-tyrosine-serine-threonine-glutamic acid- Leu-Ile-phenylalanine-tyrosine-lle-Glu-methionine-asparatate-proline, should Sequence discloses in Chinese patent application 201410123289.6.The face of the resulting Product filtrate containing saccharomycetes to make fermentation of the present invention Film Essence is the transparent supernatant liquid of colorless and odorless.Glycerol is De-Nol USP United States Pharmacopeia grade pure glycerin.
The present invention also provides a kind of preparation method of the facial mask essence of Product filtrate containing saccharomycetes to make fermentation, including it is following Step:
1) component A liquid:The golden yellow camomile extract of 0.1%-2% Sodium Hyaluronate, 0.01-1%, 0.1-4% β-Portugal are poly- Sugar, 2-10% propylene glycol, 0.5-4% butanediol, 0.1-3% acrylic acid/MA copolymer sodium and 2-10% glycerol, surplus are water.
2) component B liquid:0.05-0.5% saccharomycetes to make fermentation Product filtrate, 0.8-1.5% oligopeptides -1,0.2-6%1,2- oneself Glycol, 0.2-8%1,3- propylene glycol, 0.3-6%1,6- hexylene glycol, the pungent glycol of 0.1-3%, 0.01-0.15% decoyl hydroximic acid With 0.1-5% hexylene glycol;
Wherein, the gross mass of component A liquid and component B liquid is very 100%;
3) production equipment used is cleaned up, is disinfected, for use;
4) step 1) obtained component A liquid is added in ingredients pot, opens homogenizer, homogeneous is heated to grainless object After 80-85 DEG C, speed of agitator 35r/min, heat preservation 30 minutes, each ingredient in component A liquid is sufficiently dissolved;
5) when the resulting mixed solution temperature of step 4) is down to 42 DEG C, step 2) obtained component B liquid is added, unlatching is stirred It mixes, mixing speed 30r/min, stirs 20 minutes;
6) when the resulting mixed solution temperature of step 5) is down to 38 DEG C, laboratory detection (including appearance, PH are sent in sampling Value, lead content, arsenic content and mercury content etc.), qualified (meeting industry quality standard), filtering and discharging, standing were anti-to get maintenance afterwards The facial mask essence of aging.
The facial mask essence of gained Product filtrate containing saccharomycetes to make fermentation of the invention is filled using individual packets.
Embodiment 1
A kind of facial mask essence of the Product filtrate containing saccharomycetes to make fermentation, the ingredient including following mass percents:
The golden yellow camomile extract of 0.1%-0.3% Sodium Hyaluronate, 0.01-0.08%, 0.1-2% beta glucan, 2- 3% propylene glycol, 0.5-1% butanediol, 0.1-1% acrylic acid/MA copolymer sodium, 2-4% glycerol, 0.05-0.4% saccharomycete hair Ferment Product filtrate, 0.01-0.02%N15 polypeptide, 0.8-0.9% oligopeptides -1,0.2-3%1,2- hexylene glycol, 0.2-4%1,3- third Glycol, 0.3-3%1, the pungent glycol of 6- hexylene glycol, 0.1-1%, 0.01-0.08% decoyl hydroximic acid, 0.1-3% hexylene glycol, surplus For water.
A kind of preparation method of the facial mask essence of the Product filtrate containing saccharomycetes to make fermentation, includes the following steps:
1) component A liquid:Sodium Hyaluronate, golden yellow chamomile are weighed by the mass percent of the corresponding ingredient in the present embodiment Extract, beta glucan, propylene glycol, butanediol, acrylic acid/MA copolymer sodium, glycerol, surplus is water;
2) component B liquid:Saccharomycetes to make fermentation Product filtrate, widow are weighed by the mass percent of the corresponding ingredient in the present embodiment Peptide -1,1,2- hexylene glycol, 1,3- propylene glycol, 1,6-HD, pungent glycol, decoyl hydroximic acid, hexylene glycol;
Wherein, the gross mass of component A liquid and component B liquid is very 100%;
3) production equipment used is cleaned up, is disinfected, for use.
4) step 1) obtained component A liquid is added in ingredients pot, opens homogenizer, homogeneous is heated to grainless object After 80-85 DEG C, speed of agitator 35r/min, heat preservation 30 minutes, each ingredient in component A liquid is sufficiently dissolved;
5) when the resulting mixed solution temperature of step 4) is down to 42 DEG C, step 2) obtained component B liquid is added, unlatching is stirred It mixes, mixing speed 30r/min, stirs 20 minutes.
6) when the resulting mixed solution temperature of step 5) is down to 38 DEG C, sampling send laboratory to detect, and filters out after qualified Material, stand to get maintenance anti-aging facial mask essence.
Embodiment 2
A kind of facial mask essence of the Product filtrate containing saccharomycetes to make fermentation, the ingredient including following mass percents:
0.5% Sodium Hyaluronate, 0.1% golden yellow camomile extract, 2.5% beta glucan, 4% propylene glycol, 2% fourth two Alcohol, 2.5% acrylic acid/MA copolymer sodium, 5% glycerol, 0.45% saccharomycetes to make fermentation Product filtrate, 0.025%N15 polypeptide, 1% Oligopeptides -1,4%1,2- hexylene glycol, 5%1,3- propylene glycol, 4%1,6- hexylene glycol, 2% pungent glycol, 0.1% decoyl hydroximic acid, 4% hexylene glycol, surplus are water.
A kind of preparation method of the facial mask essence of the Product filtrate containing saccharomycetes to make fermentation, includes the following steps:
1) component A liquid:Sodium Hyaluronate, golden yellow chamomile are weighed by the mass percent of the corresponding ingredient in the present embodiment Extract, beta glucan, propylene glycol, butanediol, acrylic acid/MA copolymer sodium, glycerol, surplus is water.
2) component B liquid:Saccharomycetes to make fermentation Product filtrate, widow are weighed by the mass percent of the corresponding ingredient in the present embodiment Peptide -1,1,2- hexylene glycol, 1,3- propylene glycol, 1,6-HD, pungent glycol, decoyl hydroximic acid, hexylene glycol;
Wherein, the gross mass of component A liquid and component B liquid is very 100%;
3) production equipment used is cleaned up, is disinfected, for use.
4) step 1) obtained component A liquid is added in ingredients pot, opens homogenizer, homogeneous is heated to grainless object After 80-85 DEG C, speed of agitator 35r/min, heat preservation 30 minutes, each ingredient in component A liquid is sufficiently dissolved;
5) when the resulting mixed solution temperature of step 4) is down to 42 DEG C, step 2) obtained component B liquid is added, unlatching is stirred It mixes, mixing speed 30r/min, stirs 20 minutes.
6) when the resulting mixed solution temperature of step 5) is down to 38 DEG C, sampling send laboratory to detect, and filters out after qualified Material stands to get maintenance anti-ageing face mask Essence.
Embodiment 3
A kind of facial mask essence of the Product filtrate containing saccharomycetes to make fermentation, the ingredient including following mass percents:
The golden yellow camomile extract of 0.6%-2% Sodium Hyaluronate, 0.2-1%, 3-4% beta glucan, 5-10% the third two Alcohol, 3-4% butanediol, 2.6-3% acrylic acid/MA copolymer sodium, 6-10% glycerol, the filter of 0.47-0.5% saccharomycetes to make fermentation product Liquid, 0.03-0.05%N15 polypeptide, 1.2-1.5% oligopeptides -1,5-6%1,2- hexylene glycol, 6-8%1,3- propylene glycol, 5-6%1, The pungent glycol of 6- hexylene glycol, 2.5-3%, 0.12-0.15% decoyl hydroximic acid, 4.5-5% hexylene glycol, surplus is water.
A kind of preparation method of the facial mask essence of the Product filtrate containing saccharomycetes to make fermentation, includes the following steps:
1) component A liquid:Sodium Hyaluronate, golden yellow chamomile are weighed by the mass percent of the corresponding ingredient in the present embodiment Extract, beta glucan, propylene glycol, butanediol, acrylic acid/MA copolymer sodium, glycerol, surplus is water.
2) component B liquid:Saccharomycetes to make fermentation Product filtrate, widow are weighed by the mass percent of the corresponding ingredient in the present embodiment Peptide -1,1,2- hexylene glycol, 1,3- propylene glycol, 1,6-HD, pungent glycol, decoyl hydroximic acid, hexylene glycol;
Wherein, the gross mass of component A liquid and component B liquid is very 100%;
3) production equipment used is cleaned up, is disinfected, for use.
4) step 1) obtained component A liquid is added in ingredients pot, opens homogenizer, homogeneous is heated to grainless object After 80-85 DEG C, speed of agitator 35r/min, heat preservation 30 minutes, each ingredient in component A liquid is sufficiently dissolved;
5) when the resulting mixed solution temperature of step 4) is down to 42 DEG C, step 2) obtained component B liquid is added, unlatching is stirred It mixes, mixing speed 30r/min, stirs 20 minutes.
6) when the resulting mixed solution temperature of step 5) is down to 38 DEG C, sampling send laboratory to detect, and filters out after qualified Material, stand to get maintenance anti-aging facial mask essence.
Test case
The personnel of 5 all ages and classes, gender and skin quality state are selected to produce using obtained in embodiment 2 containing saccharomycetes to make fermentation Rear skin pore, color spot, texture, roughness, acne, pigment, water are tested before it is used and used to the facial mask essence of object filtrate Point, red color area, brown spot and ultraviolet light spot variation.5 tester's facial masks are changed such as before and using each index of rear skin Shown in Fig. 1 and table 1.
Each index of skin changes statistical form before and after 1 maintenance anti-ageing face mask Essence use of table
Annotation:It is forward and backward real-time with skin decoding robot using yeast Essence that the above are 5 all ages and classes gender personnel Detect skin data.Smoothness from low to high, indicates that skin is smooth by rough texture gradually, and full marks 10 divide expression fine and smooth light It is sliding;Pore score value from low to high, indicate keratotic plug blocking to it is medium uniformly arrive it is tiny penetrating;Color spot score value indicates severe from low to high Color spot is to moderate color spot to slight color spot;Wrinkle from low to high, indicates severe wrinkle, moderate wrinkle to slight wrinkle.
By Fig. 1 and table 1 it is found that skin of 5 testers after using the resulting facial mask essence use of embodiment 2 is each Index value (pore, smoothness, color spot and wrinkle) comparison is increased using preceding, illustrates the resulting facial mask essence of the present invention Liquid has good maintenance and anti-aging effects to skin.
In the present invention, saccharomycetes to make fermentation Product filtrate, N15 polypeptide, Sodium Hyaluronate, golden yellow camomile extract and widow Peptide -1, this five kinds of main component compoundings have significant synergistic function, can significantly repair damaged cell, cell is replenished in time Nutrient improves problem flesh and remolds skin consolidation children and slides.
Finally, it is stated that the above examples are only used to illustrate the technical scheme of the present invention and are not limiting, although referring to compared with Good embodiment describes the invention in detail, those skilled in the art should understand that, it can be to skill of the invention Art scheme is modified or replaced equivalently, and without departing from the objective and range of technical solution of the present invention, should all be covered at this In the scope of the claims of invention.

Claims (5)

1. a kind of facial mask essence of Product filtrate containing saccharomycetes to make fermentation, which is characterized in that including following mass percents at Point:The golden yellow camomile extract of 0.1%-2% Sodium Hyaluronate, 0.01-1%, 0.1-4% beta glucan, 2-10% propylene glycol, 0.5-4% butanediol, 0.1-3% acrylic acid/MA copolymer sodium, 2-10% glycerol, the filter of 0.05-0.5% saccharomycetes to make fermentation product Liquid, 0.01-0.05%N15 polypeptide, 0.8-1.5% oligopeptides -1,0.2-6%1,2- hexylene glycol, 0.2-8%1,3- propylene glycol, The pungent glycol of 0.3-6%1,6- hexylene glycol, 0.1-3%, 0.01-0.15% decoyl hydroximic acid and 0.1-5% hexylene glycol, surplus are Water.
2. a kind of facial mask essence of Product filtrate containing saccharomycetes to make fermentation according to claim 1, which is characterized in that including The ingredient of following mass percents:0.5% Sodium Hyaluronate, 0.1% golden yellow camomile extract, 2.5% beta glucan, 4% Propylene glycol, 2% butanediol, 2.5% acrylic acid/MA copolymer sodium, 5% glycerol, 0.45% saccharomycetes to make fermentation Product filtrate, 0.025%N15 polypeptide, 1% oligopeptides -1,4%1,2- hexylene glycol, 5%1,3- propylene glycol, 4%1,6- hexylene glycol, 2% pungent glycol, 0.1% decoyl hydroximic acid and 4% hexylene glycol, surplus are water.
3. a kind of facial mask essence of Product filtrate containing saccharomycetes to make fermentation according to claim 1, which is characterized in that gained The Product filtrate containing saccharomycetes to make fermentation facial mask essence be the transparent supernatant liquid of colorless and odorless.
4. a kind of facial mask essence of Product filtrate containing saccharomycetes to make fermentation according to claim 1, which is characterized in that described Glycerol is De-Nol USP United States Pharmacopeia grade pure glycerin.
5. a kind of preparation method of the facial mask essence of Product filtrate containing saccharomycetes to make fermentation, which is characterized in that include the following steps:
1) component A liquid:The golden yellow camomile extract of 0.1%-2% Sodium Hyaluronate, 0.01-1%, 0.1-4% beta glucan, 2- 10% propylene glycol, 0.5-4% butanediol, 0.1-3% acrylic acid/MA copolymer sodium and 2-10% glycerol, surplus are water;
2) component B liquid:0.05-0.5% saccharomycetes to make fermentation Product filtrate, 0.8-1.5% oligopeptides -1,0.2-6%1,2- hexylene glycol, 0.2-8%1,3- propylene glycol, 0.3-6%1,6- hexylene glycol, the pungent glycol of 0.1-3%, 0.01-0.15% decoyl hydroximic acid and 0.1- 5% hexylene glycol;
3) production equipment used is cleaned up, is disinfected, for use;
4) step 1) obtained component A liquid is added in ingredients pot, opens homogenizer, homogeneous is heated to 80-85 to grainless object DEG C, speed of agitator 35r/min sufficiently dissolves each ingredient in component A liquid after heat preservation 30 minutes;
5) when the resulting mixed solution temperature of step 4) is down to 42 DEG C, step 2) obtained component B liquid is added, opens stirring, stirs Speed 30r/min is mixed, is stirred 20 minutes;
6) when the resulting mixed solution temperature of step 5) is down to 38 DEG C, sampling send laboratory to detect, it is qualified after filtering and discharging, quiet It sets to get the facial mask essence of maintenance anti-aging.
CN201811123218.0A 2018-09-26 2018-09-26 A kind of facial mask essence of the Product filtrate containing saccharomycetes to make fermentation and preparation method thereof Pending CN108836901A (en)

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CN109481327A (en) * 2018-12-04 2019-03-19 珠海依赛思生物科技有限公司 A kind of multiple-effect maintenance peptide essence composition and preparation method thereof
CN109718194A (en) * 2018-12-09 2019-05-07 广州珈源日化用品有限公司 A kind of yeast extract, oligopeptides -1 and the compact micro- face stoste of acetyl group hexapeptide -1
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CN114469808B (en) * 2022-01-28 2024-03-19 拉芳家化股份有限公司 Preparation method of antioxidant nanoemulsion containing yeast peptide and application of antioxidant nanoemulsion in cosmetics
CN117205102A (en) * 2023-10-20 2023-12-12 安徽全康药业有限公司 Facial mask patch containing active peptide and preparation method

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Application publication date: 20181120