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CN108815318A - A kind of composition for immunological enhancement containing the lactobacillus and preparation method thereof and purposes - Google Patents

A kind of composition for immunological enhancement containing the lactobacillus and preparation method thereof and purposes Download PDF

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CN108815318A
CN108815318A CN201811102021.9A CN201811102021A CN108815318A CN 108815318 A CN108815318 A CN 108815318A CN 201811102021 A CN201811102021 A CN 201811102021A CN 108815318 A CN108815318 A CN 108815318A
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肖月华
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/58Reptiles
    • A61K35/583Snakes; Lizards, e.g. chameleons
    • AHUMAN NECESSITIES
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    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
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    • A61K35/65Amphibians, e.g. toads, frogs, salamanders or newts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/87Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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Abstract

The invention discloses a kind of composition for immunological enhancement containing the lactobacillus and preparation method thereof and purposes, the composition includes according to parts by weight:20 parts of yellow meal worm, 1 part of house liyard powder, 1 part of toad powder, 1 part of radix ranunculi ternati, 1 part of tetratigma hemsleyanum, 5 parts of Li Wangcao.Preferably, the composition includes by weight:Yellow meal worm 20g, house liyard powder 1g, toad powder 1g, radix ranunculi ternati 1g, tetratigma hemsleyanum 1g, Li Wangcao 5g.The present invention also provides the preparation method of the composition and purposes.This method is:Each medicine material is weighed in proportion, is dried, then grinds and is sieved respectively, is remixed uniformly, last bagging and packaging.The composition is used to prepare the oral granule of strengthen immunity.The present invention has the characteristics that few reasonable recipe, dosage, significant effect, has no toxic side effect, take orally can effective strengthen immunity it is high to can be also used for anti-aging, treatment three especially suitable for cancer patient.

Description

A kind of composition for immunological enhancement containing the lactobacillus and preparation method thereof and purposes
Technical field
The present invention relates to a kind of composition and preparation method thereof and purposes, and in particular, to one kind is used for strengthen immunity Composition and preparation method thereof and purposes.
Background technique
Immunity is the defense mechanism of human body itself, is that human bioequivalence and any foreign matter of the external intrusion of elimination are (viral, thin Bacterium etc.), handle the own cells of aging, damage, death, denaturation, and identification and processing vivo mutations cell and virus infection The ability of cell is human bioequivalence and the physiological reaction for excluding " dissident ".
Immunity is that body resists external invasion, safeguards the ability of homoiostasis.It is filled in air various each The microorganism of sample:Bacterium, virus, mycoplasma, Chlamydia, fungi etc..In the hypodynamic situation of human immunity, they all may be used To become the pathogen of class as early as possible.Although human body can generate corresponding antibody to different pathogen, to resist subinfection again, Antibody has specificity and time-bounded, for example, hammer bacteria antibody can only be protected in short period of time body not by it is streptococcic again Secondary infringement can not also resist the infection of other viruses.
Modern medical science discovery, being immunized is the factor for having substantial connection with aging, and immunocyte decline is aging One of most important reason.Some special cells of body immune system can will invade intracorporal bacterium, virus and decline in vivo Old dead cell, the cell being mutated and the substance for causing allergy, are wholly swallowed and are eliminated, from internal ring The stabilization in border keeps body health.But body's immunity began to decline at 30 years old or so, it is this variation be quietly, slowly, It is continued for.
The body of hypoimmunity is easy to infected or cancer stricken;Immunity is extraordinary also to generate insalubrious knot Fruit, such as cause allergic reaction, autoimmune disease.
A variety of causes prevents immune system from normally playing protective effect, in the case, easily incur bacterium, virus, The infection such as fungi, therefore it is exactly liable to illness that hypoimmunity, which most directly shows,.Because of frequent illness, disappearing for body has been aggravated Consumption, thus generally have a delicate constitution, malnutritive, apathetic, fatigue and weak, loss of appetite, sleep disturbance etc. show, give birth to Disease, having an injection to take medicine has become homely food.It is sick every time to be lot more time to restore, and usually recurrent exerbation.Grow this It will lead to physical and intellectual depauperation in the past, and also easily induced major disease.Underlying causes be hypoimmunity or immunity not It is sound.When immune function of human body imbalance or unsound immune system, following point will recurrent exerbation:Flu is sent out repeatedly Work, tonsillitis recurrent exerbation, asthma recurrent exerbation, bronchitis recurrent exerbation, pneumonia recurrent exerbation, diarrhea recurrent exerbation.
Due to having the function of that the food of strengthen immunity or medicament categories are various, collocation using can above allow people without fitting From.The effect of strengthen immunity is maximized, and does not generate adverse reaction or toxic side effect, is the problem for needing to solve.
Summary of the invention
The object of the present invention is to provide a kind of composition and preparation method thereof and purposes, are able to solve existing issue, are used for Strengthen immunity also has multi-efficiency especially suitable for cancer patient, and such as anti-aging, treatment three is high and prescription closes Reason, dosage is few, significant effect, the features such as having no toxic side effect.
In order to achieve the above object, the present invention provides a kind of composition for immunological enhancement containing the lactobacillus, wherein the composition Include according to parts by weight:20 parts of yellow meal worm, 1 part of house liyard powder, 1 part of toad powder, 1 part of radix ranunculi ternati, 1 part of tetratigma hemsleyanum, multitude king 5 parts of grass.
Above-mentioned composition for immunological enhancement containing the lactobacillus, wherein the composition includes by weight:Yellow meal worm 20g, House liyard powder 1g, toad powder 1g, radix ranunculi ternati 1g, tetratigma hemsleyanum 1g, Li Wangcao 5g.
The present invention also provides the preparation methods of above-mentioned composition for immunological enhancement containing the lactobacillus, wherein the method For:Each medicine material is weighed in proportion, is dried, then grinds and is sieved respectively, is remixed uniformly, last envelope packet Dress.
The preparation method of above-mentioned composition for immunological enhancement containing the lactobacillus, wherein broken grain is ground in the method Degree range is 30~50 mesh.
The preparation method of above-mentioned composition for immunological enhancement containing the lactobacillus, wherein the bagging and packaging in the method, often Solid weight in bag is 28~30g.
Present invention provides the purposes of the composition of above-mentioned method preparation, wherein the composition is used to prepare The oral granule of strengthen immunity.
The purposes of the composition of above-mentioned method preparation, wherein the electuary passes through warm water when in use and brews clothes With twice daily, being taken respectively at half an hour after meal, three months as a treatment course.
The purposes of the composition of above-mentioned method preparation, wherein the electuary includes in every bag each taking one bag Yellow meal worm 20g, house liyard powder 1g, toad powder 1g, radix ranunculi ternati 1g, tetratigma hemsleyanum 1g, Li Wangcao 5g.
Composition provided by the present invention for strengthen immunity and preparation method thereof has the following advantages that with purposes:
Composition provided by the present invention has many advantages, such as that reasonable recipe, dosage be few, significant effect, and taking orally can be effective Improve immunity, additionally it is possible to which body-building, enhancing physical strength etc. can be also used for anti-aging, treatment especially suitable for cancer patient Three is high.Have simultaneously pure natural no added, plants herb has no toxic side effect, not wound body the features such as, hence it is evident that better than similar function The product of energy.
Specific embodiment
A specific embodiment of the invention is further described below.
Provided by the present invention for the composition of strengthen immunity, include according to parts by weight:20 parts of yellow meal worm, house liyard powder 1 part, 1 part of toad powder, 1 part of radix ranunculi ternati, 1 part of tetratigma hemsleyanum, 5 parts of Li Wangcao.
Preferably, the composition includes by weight:Yellow meal worm 20g~30g, house liyard powder 1g~2g, toad powder 1g~2g, Radix ranunculi ternati 1g~2g, tetratigma hemsleyanum 1g~2g, Li Wangcao 5g~10g.
Wherein, yellow meal worm takes dry product.Yellow meal worm is called bread worm, foreign insects, and coleoptera is under the jurisdiction of on entomological taxonomy, intends Carabidae, meal beetle Eimeria (Tenebrio).Yellow meal worm dry product fatty 30% is up to 50% or more containing protein, furthermore Also containing macroelements and various trace elements such as phosphorus, potassium, iron, sodium, aluminium.Medical research proves that the riboflavin of yellow meal worm and VE contain Amount is all very high, and VE has the antioxidation for protecting the lipid in cell membrane to damage from peroxide, is a kind of indispensable Nutrient and drug.Not only protein content is high for yellow meal worm, but also the essential amino acid containing A wide selection of colours and designs.Yellow meal worm fat contains There is unsaturated fatty acid abundant, the crease-resistant function that can improve skin as fat medical and used for cosmetic can be purified, to skin Disease also plays the role of certain treatment and alleviates symptom, and using yellow meal worm is that raw material extracts SOD as beauty and health care products material, Anti-aging, wrinkle resistant, whitening, beauty treatment effect are also superior to existing market product.The distinctive chitin of yellow meal worm and antibacterial peptide, there is reduction Blood pressure improves immune, activating cell, pre- anti-cancer, reducing blood lipid, blood pressure lowering, adjusts blood glucose, anti-aging, adjusts body environment etc. Multiple functions effect, can be used for medical product and health product.Make the medicinal of benefiting qi and nourishing blood.There is activating microcirculation and removing stasis medicinal, middle benefit gas qi-regulating is gone back Nameless sores or boils can be controlled.With safflower, jujube, English walnut three kinds of drugs raising, the pharmacological property of foreign insects can be enhanced, promote human body fully absorb and It utilizes, reconciles the equilibrium between yin and yang of blood forming organ, reach kidney tonifying, essence replenishing benefit marrow, spleen benefiting and replenishing qi and blood, heat clearing and blood cooling removing toxic substances, promoting the circulation of qi work Blood and dissolving stasis effect.Foreign insects can treat the low property anaemia of myelosis, secondary anemia, thrombopenia, platelet function Obstacle disease, coagulation factor deficiency etc., curative effect is favourable, and efficient, remission rate reaches 100%, and cure rate is up to 85% or more. Treatment leukaemia also has certain effect, it can improve the remission rate of leukaemia, extends life cycle.The by-product of foreign insects, as frass, The impurity such as worm skin have the function of promoting blood circulation, swelling and pain relieving;Treat subcutaneous congested, swelling and other effects caused by contusion, strain Significantly.Studies have shown that foreign insects also have good anti-aging effects.In treatment tumour, while using chemotherapeutics, using ocean Worm can improve body's immunity, reduce the toxic side effect of chemotherapeutics, and there are also certain synergistic effects.Foreign insects can reduce The toxic side effect of cyclophosphamide has significant protection to make caused by cyclophosphamide atrophy of immune organ, oligoleukocythemia, weight loss With, and enhance the inhibiting effect to tumour.
House liyard powder is gecko dry product institute levigation end.Gecko is Gekkonidae animal without wart gecko or without web gecko or more mole geckoes Entirety.It is distributed in one band of China southeast, no web gecko originates in northeast and North China.Summer, autumn capture, and can be lured in night with light It catches.Using fresh herb or catch it is rear with bamboo chip through head abdomen, tail is restricted and is fixed on bamboo chip, is then dried with small fire.When acquisition processing, It should be noted that tail portion is not made to fall off.Taste is salty, cold in nature.Return kidney, Liver Channel.It is active with wind-dispelling, the effect of dissipating bind.It is usually used in middle paralysis Paralysis, rheumatic arthritis, osteomyelitis, scrofula, the cancer of the esophagus, lung cancer, primary carcinoma of liver, intestinal cancer etc..
Toad powder is toad dry product institute levigation end.Toad is the complete of Bufonidae animal bufo gargarizans Cantor or Bufo melanostictus etc. Body.Summer, autumn capture.Catch after, first adopt the dried venom of toads, then kill toad, directly dry (northeast, North China);Or it is removed after killing It goes internal organ to strut body cavity and dries (East China, Central-South, south China).This dry toad, commodity are known as dry toad, remove the commodity of internal organ It practises and claims dry maxima skin.Nature and flavor are pungent, cool, toxic.Enter the heart, liver, spleen, lung four to pass through.With broken crux, row water-wet, detoxification, desinsection, analgesic therapy Etc. functions.Cure mainly furunculosis, carbuncle on the back, negative subcutaneous ulcer scrofula, malignant sore, the abdominal mass hypochondriac lump, tympanites, oedema, infantile malnutrition, chronic bronchitis.
Radix ranunculi ternati is the dried root of ranunculaceae plant Seynuns Kugelann.It is distributed in Guangxi, Taiwan, Jiangsu, Zhejiang, Jiangxi, lake The ground such as south, Anhui, Hubei, Henan.Spring excavation, removes fibrous root and silt, dries.It is sweet in flavor, pungent, it is warm-natured.Return liver, lung channel.Tool There are reducing phlegm and resolving masses, the efficacy of removing toxicity for detumescence effect.It is usually used in scrofula subcutaneous nodule, furuncle swelling toxin, snakebite and bugbite.
Tetratigma hemsleyanum is the cauline leaf that vitaceae Tai Wanya climbs rattan.It is distributed in Taiwan.Summer, autumn harvesting, using fresh herb or Slice, is dried.Bitter, it is cold in nature.Returns spleen, stomach meridian.There is the effect of myogenic sore.It is usually used in wound.
Li Wangcao scientific name crocodile mouth flower is the plant that Acanthaceae crocodile mouth flower belongs to.It is known as Sambucus thunbergiana in Hainan.It is sweet in flavor, pungent, micro- It is bitter, mild-natured, enter liver and kidney channel.It is a kind of be grown in equatorial low altitude area sparse woods or in shrubbery in moist sandy soil Wild bush shape herbaceous plant, maturity period are generally 3-9 months.It is the edible wild herbs that a kind of nutritive value is very high, nontoxic, green agricultural production Product, it is high containing amino acid and chlorophyll.It is shown according to result of laboratory test:It is nontoxic, contain lupeol, betulin, pentacyclic triterpene It is high to close object, Beta sitosterol, calcium constituent, Flavonoid Content.Complete stool is used as medicine, and clearing heat and detoxicating, eliminating stasis to subdue swelling, anti-inflammatory are relieved the effect of alcohol, prevented The effects of cancer anticancer, can improve systemic blood flow state, enhance cardiac contractility ability, improve blood pressure, contain protein abundant, nutrition It is worth high.It is conventionally used to treatment ephritis, nephrarctia, kidney failure, kidney stone, is the liberator of kidney patient, also can treat Throat swelling and pain, hepatitis, jaundice, skin disease, hypertension, hyperglycemia, hyperlipidemia, gastritis, rheumatic arthralgia, and have to kinds cancer Good therapeutic effect.
The present invention also provides the preparation method of the composition for immunological enhancement containing the lactobacillus, this method is:It weighs in proportion Each medicine material, is dried, and then grinds and is sieved respectively, remixes uniformly, last bagging and packaging.
Preferably, grinding broken particle size range is 30~50 mesh.Solid weight in every bag of bagging and packaging is 28~ 30g。
Present invention provides the purposes of the composition of this method preparation, the composition is used to prepare the mouth of strengthen immunity Take electuary.
The electuary, which passes through warm water when in use and brews, to be taken, and twice daily, is taken respectively at half an hour after meal, three months It is as a treatment course.
The electuary includes yellow meal worm 20g, house liyard powder 1g, toad powder 1g, radix ranunculi ternati 1g, three in every bag each taking one bag Rattan 1g, Li Wangcao 5g are climbed in leaf precipice.
Below with reference to embodiment to composition provided by the present invention for strengthen immunity and preparation method thereof and purposes It is further described.
Embodiment 1
A kind of composition for immunological enhancement containing the lactobacillus includes according to parts by weight:20 parts of yellow meal worm, 1 part of house liyard powder, toad 1 part of powder, 1 part of radix ranunculi ternati, 1 part of tetratigma hemsleyanum, 5 parts of Li Wangcao.
Each raw material corresponds with corresponding national standard.
The present embodiment additionally provides the preparation method of the composition for immunological enhancement containing the lactobacillus, and the composition prepared Purposes.
This method is:Each medicine material is weighed in proportion, is dried, then grinds and is sieved respectively, and grinding is broken Broken particle size range is 30~50 mesh.It remixes uniformly, last bagging and packaging.Solid weight in every bag of bagging and packaging is 28 ~30g.
The present embodiment also provides the purposes of the composition of this method preparation, and the composition is used to prepare strengthen immunity Oral granule.
The electuary, which passes through warm water when in use and brews, to be taken, and twice daily, is taken respectively at half an hour after meal, three months It is as a treatment course.
The electuary includes yellow meal worm 20g, house liyard powder 1g, toad powder 1g, radix ranunculi ternati 1g, three in every bag each taking one bag Rattan 1g, Li Wangcao 5g are climbed in leaf precipice.
Oral granule is made using composition prepared by embodiment 1, and hypoimmunity shape is in over thousands of example at random The patient of state has carried out the diagnosis and treatment based on an overall analysis of the illness and the patient's condition clinical test of parting, and efficient up to 88% or more, obvious effective rate reaches 93% or more, full Meaning degree reaches 97% or more.
Composition provided by the present invention for strengthen immunity and preparation method thereof and purposes, for the cause of disease disease of disease Machine, using the complementary compatibility principle of drug, purposefully by all medicines by monarch, institutional framework reasonable compatibility minister, helped, made, Drug and its compatibility in the side of making and the interpretation of the cause, onset and process of an illness of disease are intricately woven together, the aggreggate utility after making compatibility of drugs and vertical therapy height It is unified.The composition is to have passed through the clinical test of many cases, to the function of its every herbal medicine and is cured mainly and according to modern Chinese and Western A kind of prescription curing pharmacological research and being formed, has the spy that formula is scientific and reasonable, production method is simple and easy, easy to spread Point, can effective strengthen immunity it is high to can be also used for anti-aging, treatment three, and invariably especially suitable for cancer patient Good reaction and side effect.
It is discussed in detail although the contents of the present invention have passed through above preferred embodiment, but it should be appreciated that above-mentioned Description is not considered as limitation of the present invention.After those skilled in the art have read above content, for of the invention A variety of modifications and substitutions all will be apparent.Therefore, protection scope of the present invention should be limited to the appended claims.

Claims (8)

1. a kind of composition for immunological enhancement containing the lactobacillus, which is characterized in that the composition includes according to parts by weight:
20 parts of yellow meal worm, 1 part of house liyard powder, 1 part of toad powder, 1 part of radix ranunculi ternati, 1 part of tetratigma hemsleyanum, 5 parts of Li Wangcao.
2. composition for immunological enhancement containing the lactobacillus as described in claim 1, which is characterized in that the composition is by weight Include:
Yellow meal worm 20g, house liyard powder 1g, toad powder 1g, radix ranunculi ternati 1g, tetratigma hemsleyanum 1g, Li Wangcao 5g.
3. a kind of preparation method of composition for immunological enhancement containing the lactobacillus as claimed in claim 1 or 2, which is characterized in that institute The method stated is:Each medicine material is weighed in proportion, is dried, then grinds and is sieved respectively, is remixed uniformly, most Bagging and packaging afterwards.
4. the preparation method of composition for immunological enhancement containing the lactobacillus as claimed in claim 3, which is characterized in that the method The broken particle size range of middle grinding is 30~50 mesh.
5. the preparation method of composition for immunological enhancement containing the lactobacillus as claimed in claim 3, which is characterized in that the method In bagging and packaging, the solid weight in every bag is 28~30g.
6. a kind of purposes of the composition of method as claimed in claim 3 preparation, which is characterized in that the composition is used for Prepare the oral granule of strengthen immunity.
7. the purposes of the composition prepared method as claimed in claim 6, which is characterized in that the electuary leads to when in use It crosses warm water and brews and take, twice daily, taken respectively at half an hour after meal, three months as a treatment course.
8. the purposes of the composition prepared the method for claim 7, which is characterized in that the electuary, each taking One bag, include yellow meal worm 20g, house liyard powder 1g, toad powder 1g, radix ranunculi ternati 1g, tetratigma hemsleyanum 1g, Li Wangcao 5g in every bag.
CN201811102021.9A 2018-09-20 2018-09-20 A kind of composition for immunological enhancement containing the lactobacillus and preparation method thereof and purposes Pending CN108815318A (en)

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