CN1087014A - Scabies ointment and preparation method thereof - Google Patents
Scabies ointment and preparation method thereof Download PDFInfo
- Publication number
- CN1087014A CN1087014A CN 93111883 CN93111883A CN1087014A CN 1087014 A CN1087014 A CN 1087014A CN 93111883 CN93111883 CN 93111883 CN 93111883 A CN93111883 A CN 93111883A CN 1087014 A CN1087014 A CN 1087014A
- Authority
- CN
- China
- Prior art keywords
- scabies
- ointment
- calomelas
- talcum
- sodium chloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 206010063409 Acarodermatitis Diseases 0.000 title claims abstract description 30
- 241000447727 Scabies Species 0.000 title claims abstract description 30
- 208000005687 scabies Diseases 0.000 title claims abstract description 30
- 239000002674 ointment Substances 0.000 title claims abstract description 16
- 238000002360 preparation method Methods 0.000 title claims abstract description 5
- 239000003814 drug Substances 0.000 claims abstract description 20
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 18
- PAWQVTBBRAZDMG-UHFFFAOYSA-N 2-(3-bromo-2-fluorophenyl)acetic acid Chemical group OC(=O)CC1=CC=CC(Br)=C1F PAWQVTBBRAZDMG-UHFFFAOYSA-N 0.000 claims abstract description 9
- 241001161070 Calomela Species 0.000 claims abstract description 9
- 235000019084 Selinum monnieri Nutrition 0.000 claims abstract description 9
- 229940079593 drug Drugs 0.000 claims abstract description 9
- 239000011780 sodium chloride Substances 0.000 claims abstract description 9
- 235000012222 talc Nutrition 0.000 claims abstract description 9
- 229910052623 talc Inorganic materials 0.000 claims abstract description 9
- 239000000454 talc Substances 0.000 claims abstract description 9
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 5
- 239000002671 adjuvant Substances 0.000 claims abstract description 3
- 229940099259 vaseline Drugs 0.000 claims abstract description 3
- 239000000203 mixture Substances 0.000 claims description 6
- 150000001875 compounds Chemical class 0.000 claims description 3
- 241000356446 Cnidium monnieri Species 0.000 claims 3
- 229910052787 antimony Inorganic materials 0.000 claims 2
- WATWJIUSRGPENY-UHFFFAOYSA-N antimony atom Chemical compound [Sb] WATWJIUSRGPENY-UHFFFAOYSA-N 0.000 claims 2
- 235000019640 taste Nutrition 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 9
- 244000296102 Selinum monnieri Species 0.000 abstract description 6
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract description 4
- 244000179560 Prunella vulgaris Species 0.000 abstract description 2
- 235000011158 Prunus mume Nutrition 0.000 abstract description 2
- 244000018795 Prunus mume Species 0.000 abstract description 2
- 239000011593 sulfur Substances 0.000 abstract description 2
- 229910052717 sulfur Inorganic materials 0.000 abstract description 2
- SPSSULHKWOKEEL-UHFFFAOYSA-N 2,4,6-trinitrotoluene Chemical compound CC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O SPSSULHKWOKEEL-UHFFFAOYSA-N 0.000 abstract 1
- 208000003251 Pruritus Diseases 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 230000007803 itching Effects 0.000 description 4
- HLFSDGLLUJUHTE-SNVBAGLBSA-N Levamisole Chemical compound C1([C@H]2CN3CCSC3=N2)=CC=CC=C1 HLFSDGLLUJUHTE-SNVBAGLBSA-N 0.000 description 2
- 239000005864 Sulphur Substances 0.000 description 2
- 230000000895 acaricidal effect Effects 0.000 description 2
- 239000000642 acaricide Substances 0.000 description 2
- 230000001139 anti-pruritic effect Effects 0.000 description 2
- 239000003908 antipruritic agent Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 206010002198 Anaphylactic reaction Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 208000010201 Exanthema Diseases 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 241000130764 Tinea Species 0.000 description 1
- 208000002474 Tinea Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 206010000269 abscess Diseases 0.000 description 1
- 230000036783 anaphylactic response Effects 0.000 description 1
- 208000003455 anaphylaxis Diseases 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 201000005884 exanthem Diseases 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 210000004247 hand Anatomy 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 229960001614 levamisole Drugs 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 230000000590 parasiticidal effect Effects 0.000 description 1
- 239000002297 parasiticide Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 206010037844 rash Diseases 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 201000005404 rubella Diseases 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000006748 scratching Methods 0.000 description 1
- 230000002393 scratching effect Effects 0.000 description 1
- 206010040882 skin lesion Diseases 0.000 description 1
- 231100000444 skin lesion Toxicity 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000002636 symptomatic treatment Methods 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 210000000707 wrist Anatomy 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention is scabies ointment and preparation method thereof, and its principal agent is ammonium nitrate, sodium chloride and TNT, and accessory drugs is that Calomelas, he are given birth to and cnidium monnieri, and adjuvant drug is a Talcum.Earlier TNT, Calomelas, he lifes, cnidium monnieri, Talcum are mixed behind the levigation respectively, the vaseline remix of adding equivalent is even, adds ammonium nitrate and sodium chloride at last.This scabies ointment is controlled scabies, and to kill prunus mume (sieb.) sieb.et zucc. curative effect spy good, and one wipes promptly antipruriticly, heals never recurrence entirely in two days.Owing to do not contain sulfur, sal prunella, the fire point does not fire, and is all very safe in use and the transportation.
Description
The present invention relates to the Chinese medicine technical field, belong to the department of dermatologry external used medicine.
Scabies is because sarcoptic mite is invaded the susceptible disease of human body skin, contact patient's bedding, sheet, underwear, shaking hands all with the patient may be directly, indirect infection, fall ill about about first quarter moon, be mainly in the tender thin part of skin, webs, wrist elbow, oxter, breast (lower abdomen) or spread all over whole body, the back of scratching becomes abscess.This disease is multiple, commonly encountered diseases in the old society, and it is higher that capitalist country remains national sickness rate such as frequently-occurring disease, especially Burma, the India torrid zone now.For many years, China all adopts sulphur ointment to apply medicinal lotion or ointment sooner or later every day, but effect is bad, again and again, does not prolongedly heal.Find no the patent application of the scabies medicine of same composition prescription through new patent searching, as Chinese patent " acaricide demodicid mite (tinea) compositions and production method " (9111368.1), " production method of scabies spirit and technology " (90105583.2), and for example Romanian patent " parasiticide, kill mould and fungicidal ointment " (R076.918) (1981.7.30 is open).Hungarian patent " the ointment glue of treatment scabies " (Huhg.Telges, 13,370(1977.6.28 is open), DRP " with tetramisole or L-tetramisole or their salts for treating scabies " (Ger offen 2,828,200(1979.1.4 open) etc. domestic and international patent, their prescription all is different from the present invention, and curative effect is outstanding, just reduce 30% or come into force after the treatment one-period that has, treatment time is long, has repeatedly, does not therefore have specially good effect.
Poor effect and the bad shortcoming of sulphur ointment curative effect for the Drug therapy scabies that overcomes above-mentioned patent report the invention provides a kind of specific scabies ointment, to solve painful and worried that the scabies patient feels embarrassed to mention.
Compound compatibility of the present invention is: ammonium nitrate (principal agent), sodium chloride (principal agent), TNT (principal agent), Calomelas (accessory drugs), he are given birth to (accessory drugs), cnidium monnieri (accessory drugs), Talcum (adjuvant drug).The concrete content ratio of its medicine is: ammonium nitrate 35-45%, sodium chloride 15-25%, TNT 15-25%, Calomelas 5%, he life 5%, cnidium monnieri 5%, Talcum 5%.Wherein ammonium nitrate plays the molecular chemistry effect, and sodium chloride helps skin, the high specific chemical action of messenger drug, and the strong anti-prunus mume (sieb.) sieb.et zucc. acaricide of TNT is extremely safe again, and Calomelas is controlled scabies and is killed prunus mume (sieb.) sieb.et zucc., and the living dampness of he is anticorrosion antipruritic, and cnidium monnieri is controlled malignant boil dampness, and the Talcum promoting defecation and urination helps drug effect.
Pharmaceutical technology: earlier with TNT, Calomelas, he life, cnidium monnieri, Talcum five kinds of Chinese medicine difference levigation, can not mix levigation, again five kinds of Chinese medicine is mixed behind the ground powder, adding is to vaseline (grease) mix homogeneously of equivalent, add at last ammonium nitrate and sodium chloride scabies ointment, bottling can be adorned 50 grams, and bottle or 100 one bottle two kinds of grams are bottled.
The treatment usage: wipe earlier predilection site, as skin lesion place, scabies rice, after having wiped again from newly by neck, no matter have or not the skin of scabies generally to wipe whole body downwards, children's's women's head-ornaments are wiped less, wipe several times more, wipe once next day again, scabies heals (using micrography) entirely, no longer repeatedly.Must be noted that during treatment: (1) is strictly on guard against that mistaken diagnosis, this scabies ointment are specially to control the special-purpose medicine of scabies, and is antipruritic once wiping, and heals entirely in two days.All invalid fully to other rubellas, eczema, skin ulcer rash and all anaphylaxis itching sore and old man because of skin itching of wind syndrome due to blood-deficiency etc.(2) patient who has is mingled with again other itching sore, and scabies has been cured, other itching sore also must symptomatic treatment (3) scabies entirely more after, do not cause with people's contact of suffering from scabies again and infect the regeneration scabies again in order to avoid think scabies by mistake and do not heal.(4) patient's medicated clothing answers scalding or burning sun to tan by the sun, in order to avoid infect again.
This scabies ointment therapeutic effect illustration:
Ou Zhiwen: (man) 56 years old, catch scabies through with " scabies ointment " treatment, one apply medicinal lotion or ointment promptly antipruritic, two days complete more, do not have repeatedly so far.
Liu Qingquan: (man) suffers from the scabies disease, and nineteen ninety is with " scabies ointment " treatment, one applies medicinal lotion or ointment promptly antipruriticly at that time, and two complete, do not have repeatedly so far.
In addition, the double tower welfare plastics maker people more than ten of Dazu County suffers from scabies, and the several months fails to respond to any medical treatment, and is antipruritic at once through adopting " scabies ointment " treatment, heals entirely in two days, do not have repeatedly.
The advantage of scabies ointment of the present invention:
1, with medicine of the present invention treatment scabies, one wipes promptly antipruriticly, and complete never recurrence in two days, its curative effect spy are good, use nontoxic and other the attached effects of this medicine.
2, compound compatibility science of the present invention, reasonable, optimization.
Though 3, contain TNT in this scabies ointment but owing to do not contain sulfur, sal prunella, the fire point does not fire, baked wheaten cakeizations water is so all be perfectly safe in use or transportation.
Claims (2)
1, a kind of scabies ointment and preparation method thereof, it is characterized in that, its compound compatibility is to think antimony by principal agent ammonium nitrate, sodium chloride and antimony, accessory drugs Calomelas, he are given birth to and cnidium monnieri, compositions such as adjuvant drug Talcum, the concrete content ratio of its medicine is: ammonium nitrate 35-45%, sodium chloride 15-25%, TNT 15-25%, Calomelas 5%, he life 5%, cnidium monnieri 5%, Talcum 5%.
2, according to described scabies ointment of claim 1 and preparation method thereof, it is characterized in that, earlier TNT, Calomelas, he lifes, cnidium monnieri, Talcum five tastes medicine are mixed behind the levigation respectively, and adding is to the vaseline mix homogeneously of equivalent, adds ammonium nitrate, sodium chloride again.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 93111883 CN1087014A (en) | 1993-07-02 | 1993-07-02 | Scabies ointment and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 93111883 CN1087014A (en) | 1993-07-02 | 1993-07-02 | Scabies ointment and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1087014A true CN1087014A (en) | 1994-05-25 |
Family
ID=4989636
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 93111883 Pending CN1087014A (en) | 1993-07-02 | 1993-07-02 | Scabies ointment and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1087014A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1056060C (en) * | 1996-06-19 | 2000-09-06 | 李正堂 | Scabies ointment |
-
1993
- 1993-07-02 CN CN 93111883 patent/CN1087014A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1056060C (en) * | 1996-06-19 | 2000-09-06 | 李正堂 | Scabies ointment |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| C10 | Entry into substantive examination | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |