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CN108619214A - A kind of drug for treating tumour - Google Patents

A kind of drug for treating tumour Download PDF

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Publication number
CN108619214A
CN108619214A CN201710153240.9A CN201710153240A CN108619214A CN 108619214 A CN108619214 A CN 108619214A CN 201710153240 A CN201710153240 A CN 201710153240A CN 108619214 A CN108619214 A CN 108619214A
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drug
tumour
packets
cancer
cell
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王慎君
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
    • A—HUMAN NECESSITIES
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    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/223—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of alpha-aminoacids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
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    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/64—Insects, e.g. bees, wasps or fleas
    • A61K35/644—Beeswax; Propolis; Royal jelly; Honey
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/41—Crassulaceae (Stonecrop family)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
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    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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Abstract

The present invention relates to drugs, in particular it relates to a kind of drug for treating tumour.The curing oncoma drug of the present invention purifies the blood poison for means, rather than as traditional chemotherapeutic treats tumour to kill tumour cell as means to improve mood, confidence and purification blood.This drug improves mood, the ingredient of confidence has tobacco acid, psilocybin, rhodiola root extract, and the ingredient for purifying blood has lipoic acid, propolis and pangamic acid calcium.This drug solve the problems, such as traditional chemotherapeutic also and meanwhile kill healthy cell to accelerate patient that tumour diffusion and novel tumor medicine molecular targeted medicine be only consistent to target spot effectively and after one period the targeting medicine also make metastases, recur.

Description

A kind of drug for treating tumour
Technical field
The present invention relates to a kind of drugs, in particular it relates to a kind of drug for treating cancer.
Background technology
Tumour be animals and humans organ-tissue cell it is external and it is interior under the long term of adverse factor produced by It is a kind of using cell hyperproliferation as the neoformation of main feature, it can be divided into benign tumour and malignant tumour two major classes, cancer It is then a kind of malignant tumour.
According to statistics, in global 7,000,000,000 populations, ten thousand people about more than 1000 suffer from cancer every year, because cancer died is up to hundreds of Ten thousand.Have multiple countries and regions now and cancer is classified as first cause of the death, there are a countries and regions at least more than 20 to be classified as cancer It is only second to the second largest cause of the death of cardiovascular and cerebrovascular disease.At the beginning of liberation, cancer occupied the 9th of China's cause of the death, to 90 years 20th century In generation, just cancer once occupied the cause of the death first in China.The latest data of the publication of Chinese tumour Register 2 months 2016 shows, I State is estimated to be 4,290,000 cancer new cases for 2015, because of cancer death toll more than 2,810,000.It can be seen that the prevention of cancer and controlling Treatment has become the public health problem that China should pay much attention to.
The treatment of tumour mainly has operation, drug therapy, radiotherapy, cellular immunotherapy etc..Current drug therapy Based on chemical synthetic drug treatment (referred to as " chemotherapy ").Facts proved that this for the purpose of killing tumour cell, rather than Tumour cannot be cured for the therapy of the basic reason of tumour formation.On the contrary, it is because while killing tumour cell, also killing Healthy cell makes patients immune system further destroy and patient tumors can be made to accelerate diffusion.(refer to September in 2014 30《It is long Longevity health report》1st edition《Cancer also has natural enemy！Tackle the jinx of cancer：Immunocyte！》One text)
It as the saying goes：" pulling the grass up by its roots, cure the disease and ask source ".The root of disease formation is found, therapy is also just readily solved.
Scientific research proves that blood poison is excessively the chief culprit that tumour generates.When blood toxicity is excessive in vivo, if again without abundance Nutrition supply oneself will manufacture enzyme and blood vessel, evolve into malignant tumour.It (refers to Fujian science tech publishing house to go out for 2013 Version, Wu Yongzhi write《Food is allowed to become your healthy good medicine with movement》One book page 33).
Separately there is scientific research to prove, anoxic can cause the excretion of vivotoxin to be obstructed.(Huaxia Press's publication is referred to, it is tall Will perseverance writes《Science anti-aging, health arrive at the age of one hundred years old》One book page 28, version in 2012) therefore, anoxic can cause vivotoxin to be put aside, It is damaged, makes a variation to make cell long-period be immersed in poison ring border, ultimately form tumour cell.It can be seen that anoxic is then facilitated Tumour is formed.
Also scientific research proves, stress can also make body generate toxin, and generated toxin is bromatotoxin Tens times of element.(refer to the publication in 2013 of Fujian science tech publishing house, Wu Yongzhi writes《Allow food with movement as your strong Health good medicine》One book page 63) Pharmaceutical study institute of Monash University knubble biological scholar doctor Ai Likasilong Results of animal show that stress is big, fast 6 times of cancer cell diffusion while interfering being smoothed out for treatment of cancer.(according to On July 8th, 2016 Beijing《Life Times》3rd edition《Pressure is big, fast six times of cancer diffusion》One text) it can be seen that make to swell Tumor energy rehabilitation, good mood are even more important.
In view of the foregoing, curing oncoma medicine should remove blood toxicity as first object to purify blood, and purify blood, Mood must be improved again, improve confidence and eliminate body anoxia phenomenon.
The study found that tobacco is sour, psilocybin, rhodiola root can improve mood, inspires enthusiasm；Pangamic acid calcium can eliminate human body Anoxia phenomenon；Lipoic acid, propolis can purify blood；Schizandrin, catechin, curcumin all have antitumor efficacy.But at present It does not find the curing oncoma medicine for integrating these substances in the market, also has no the patent for the curing oncoma medicine for integrating these substances Application, has then invented this drug.
The effect of this drug, ingredient included：
Tobacco acid：Also known as vitamin B7.The study found that most of tumor patients are suffering from depression.And depressive emotion meeting The treatment difficulty of disease is set to increase, case fatality rate increases.Lack tobacco acid, is filled with unbounded confidence and wishes to life originally, strong people It can become cowardly, dejected, anxiety etc..If giving subject supplements tobacco acid, after several hours, personality just becomes optimistic. It (refers to China Textiles Press to publish for 2007, light rain is write《Food can change your mood》Page 52).
Psilocybin：A kind of alkaloids plant biochemistry element extracted from mushroom, can mitigate the anxiety of cancer patient Mood.The studies have shown that of California, USA university takes the mood that 2 weeks cancer patients of psilocybin obviously suffer from spleen with anxiety Symptom mitigates, and takes psilocybin and without side-effects.It (refers to Jiangsu science tech publishing house to publish for 2014, Sun Lihong writes 《What makes people rich what is said or talked about：Anticancer, you eat right》Page 87) alkaloid can improve the confidence and will of people.And anticancer, patient based on Confidence is very crucial.Drug therapy is basis, and confidence, conviction are only the key of rehabilitation.If patient is in low spirits, burnt daily Consider, loses the confidence to life, life, other such as drug therapies, kinesiatrics, diet care are not all known where to begin.Because bad Mood will produce more toxin, these toxin are more much bigger to the harm of body than the toxin that diet, air are brought.(refer to 2016 Year June 10 mesh《Long-lived health report》Homepage《Each system toxin expelling study course of body》One text).
Rhodiola root：It is a kind of plant for being grown in highlands, has and promote endurance and antifatigue, inhibition growth of cancer cells The effects that with diffusion, compressive resistance.After taking rhodiola root, thrombocytin concentration can be improved quickly.And depression is mostly due in vivo Caused by thrombocytin deficiency.
Pangamic acid calcium：Also known as pangamic acid, it is a kind of water-soluble B vitamin.It is thin to in-vivo tissue that it can increase oxygen Body anoxia phenomenon is eliminated in the transmission of born of the same parents.(refer to China Light Industry Press's publication, Cao Jingsong, Wang Xiaoqin write《Food nutrition Hardening agent》Page 408) body anoxic is origin of hundreds of diseases.Most scholars think that human body anoxia can make body immune system lack of proper care, The excretion of internal toxin is caused to be obstructed.Vivotoxin excretion is not gone out, and cell is damaged because being immersed in poison ring border, for a long time In this way, impaired cell just generates variation, many diseases, including cancer, diabetes, cardiovascular disease etc. are then just generated.Moral The famous physician of state, Nobel's medicine is pointed out with physiology prize winner Otto professor Wa Baige, when human tissue cell's oxygen When content is less than the 65% of normal value, oxygen-starved tissue's cell is easy for canceration.(Huaxia Press's publication is referred to, Qiao Zhiheng writes《Section Anti-aging is learned, health arrives at the age of one hundred years old》Page 28, version in 2012) cancer cell is anaerobics.Oxygen is more sufficient in body, and cancer cell is got over It is difficult to survive；And normal cell, then on the contrary, oxygen is more, it is then more vibrant.Therefore, anticancer, it is necessary to eliminate body anoxic.
Lipoic acid：For a kind of biostearin antioxidant, blood, lymph and fat environment can be purified.And clean blood Liquid energy makes Denucleation become healthy cell again.(publication of Fujian science tech publishing house is referred to, Wu Yongzhi writes《Allow food with fortune It is dynamic to become your healthy good medicine》Page 83,63, version in 2013) make cancer cell " turning over a new leaf " --- it becomes healthy cell again, is cancer It is extremely valuable in disease rehabilitation course.
Propolis：The resin that be honeybee acquire from the wound of the tender shoots of certain trees or bark, and it is mixed into honeybee mandibular gland The opaque jelly of armaticity that secretion and beeswax are process, it is a kind of integration of drinking and medicinal herbs object, can improve human immunity Function, anti-oxidant, antiviral, antifatigue, antibacterial, the activity for improving superoxide dismutase, moreover it is possible to purify blood, have notable Anti-cancer function.The wild wise man of National Institutes of Health,Japan pine also doctor the study found that the diterpene product in propolis to swollen Tumor has specific killing action.After cancer patient takes propolis, not only cancer cell can disappear, but also can mitigate chemotherapy, put Toxic side effect caused by treating.China Agriculture Industitute Bee Research Center seas Liu Fu et al. pass through zoopery and practical clinical It proves, propolis has good antitumaous effect.After certain cancers patient's large dosage takes propolis, growth of cancer cells and transfer obtain very Good control, some patients even fully recover.(refer to Beijing " Golden Shield publishing house " publication in 2008, Guo Fangbin writes《Propolis Magical magical effect》Page 42, China Medical Science Press 2011 publishes, Shao Xingjun et al. writes《The strength of propolis》15th, Page 114) and to control cancer metastasis most important in treatment of cancer, because about 90% cancer mortality case is because cancer turns Caused by shifting.(according to Beijing on July 12nd, 2016《Life Times》Page 3《New method is expected to block metastasis of cancer》One text).
Schizandrin：For a kind of antioxidant in Chinese medicine Schisandra chinensis, there is anti-oxidant, inhibition inflammatory reaction, inhibition The effects that growth of cancer cells is with transfer, promotion tumor necrosis factor-alpha (TNF-α) cancer cell specific induction of apoptosis.(refer to Hunan science Technology publishing house version in 2015, the works such as Jiang Shengrong《Illustrate health food pandect》Page 61).
Epigallocatechin gallic acid：For one kind of catechin.Catechin is water soluble antioxidant, can remove people Internal free radical, it is pre- it is anti-aging, reduce cancer incidence；It can inhibit growth of cancer cells and transfer.In four kinds of catechins, table The antioxidation of gallocatechol gallic acid is best.The antioxidation of catechin is 20 times of vitamin, vitamin E 50 times or more.(refer to the works such as the publication of Hunan science tech publishing house, Jiang Shengrong《Illustrate health food pandect》Page 283,57 Page, version in 2015).
Curcumin：A kind of biochemical element of oxidation resistant plant, the study found that it can allow just becomes health in the cell reversal of canceration Cell.(according on June 4th, 2013《Long-lived health report》《Cancer, which is eaten, to be come》One text, Shanghai Univ. of Traditional Chinese Medicine professor He Yumin Text).
Selenium：For a kind of trace mineral nutrient necessary to human body and a kind of natural powerful antioxidant, there is antioxygen The effects that change, activated immune system, pre- anti-cancer and apoplexy, arthritis, Myocardial damage.In anticancer, mainly because it has side Body aid endotoxin is discharged, and tumour can be made to cannot get the supply of nutrient to be suppressed the function of growth.Selenium can also make one mood change It obtains more preferably, to beneficial to cancer rehabilitation.
Invention content
The purpose of the present invention is to provide a kind of drug for treating tumour.
The curing oncoma drug of the present invention solves traditional chemotherapeutic also while killing healthy cell to accelerate tumour thin Cancer metastasis, recurrence and the high problem of price are spread and also made after novel one period of curing oncoma medicine molecular targeted agents to born of the same parents.
Implementation steps
1, prescription：(in terms of every packet 10g)
2, production operation：It is operated by the technological process of production of granule：
1. the preparation of rhodiola root extract
A, it extracts：500g rhodiola roots are weighed, after crushing, are extracted at twice under 10-12 times of 60-70% ethanol solution room temperature It takes, each extraction time will be stirred continuously during 72h or more, extraction.It is discarded after finally filter residue is squeezed, acquired solution and two Secondary extract liquor merges, and recycles ethyl alcohol through vacuum distillation, obtains extract liquor.
B, it settles：Using gelatin tannin sedimentation.Gelatin dosage is determined according to extract liquor first, then with 10% configured Gelatin solution is added in extract liquor and is stirred continuously slowly, while appropriate diatomite is added, and settles 72h or more at normal temperatures.Through Filter filters, the other particulate matters for removing gelatin tannate complex compound and its being adsorbed.
C, refined filtration：At a temperature of 20-30 DEG C, with 0.1-0.45 μm of filter membrane refined filtration, by vacuum concentration, evaporating temperature is 70 DEG C, vacuum degree 83KPa, it is 25% or so to be concentrated into solid content.
D, it is spray-dried：Rhodiola root extraction concentrate is spray-dried at 140-150 DEG C, obtains powdered rhodiola root extraction Object.
2. Icing Sugar, citric acid, pangamic acid calcium, maltodextrin in prescription are weighed respectively by 1000 times of amounts, by their mixings After appropriate purified water be added be sufficiently stirred, become paste material.
3. weighing remaining dispensing respectively by 1000 times of amounts to be added in above-mentioned creme, the mixing in blender.
4. being granulated, drying：To be uniformly mixed, the blank of dry and wet appropriateness is with grain granulation machine granulating and forming is waved, be allowed to be in Graininess, and pass through the sieve of 6-8 mesh；Particle after molding is packed into charging tray, puts the temperature at 80-85 DEG C in dryer into Middle baking, until being dried to moisture less than 5%.
5. screening, packaging：It is in irregular shape if granular size differs, need the sieve for using 6-8 mesh to be again sieved, to remove Larger particles are removed, ensure that granular size is almost the same；Gained finished product is packed with aluminum foil sack, is sealed while hot, often packs 10g Grain, then mounted box is got product.

Claims (1)

  1. It is described to improve mood and the tobacco acid content of confidence is 1. a kind of drug for treating tumour, is technically characterized in that 1000mg/ packets, psilocybin 30mg/ packets, rhodiola root extract 500mg/ packets；The lipoic acid content for purifying blood is 350mg/ Packet, propolis content are 1000mg/ packets, and pangamic acid calcium content is 400mg/ packets；The discharge of body aid endotoxin, the table for inhibiting tumour growth Gallocatechol gallic acid content is 300mg/ packets, and it is 1.5mg/ packets to prevent the schizandrin content of metastases, makes cancer The cell reversal of change becomes the turmeric cellulose content of healthy cell as 100mg/ packets.
CN201710153240.9A 2017-03-15 2017-03-15 A kind of drug for treating tumour Pending CN108619214A (en)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10519175B2 (en) 2017-10-09 2019-12-31 Compass Pathways Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
CN110959851A (en) * 2019-11-18 2020-04-07 青海晨菲制药有限公司 Application of agaricus bisporus gallic acid in functional food
CN114040767A (en) * 2019-01-30 2022-02-11 钻石治疗公司 Methods and compositions comprising 5HT receptor agonists for the treatment of psychological, cognitive, behavioral and/or mood disorders
US11564935B2 (en) 2019-04-17 2023-01-31 Compass Pathfinder Limited Method for treating anxiety disorders, headache disorders, and eating disorders with psilocybin
US11724985B2 (en) 2020-05-19 2023-08-15 Cybin Irl Limited Deuterated tryptamine derivatives and methods of use
US12060328B2 (en) 2022-03-04 2024-08-13 Reset Pharmaceuticals, Inc. Co-crystals or salts of psilocybin and methods of treatment therewith
US12459965B2 (en) 2017-10-09 2025-11-04 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use

Cited By (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12312375B2 (en) 2017-10-09 2025-05-27 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
US12459965B2 (en) 2017-10-09 2025-11-04 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
US10947257B2 (en) 2017-10-09 2021-03-16 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
US10954259B1 (en) 2017-10-09 2021-03-23 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
US11149044B2 (en) 2017-10-09 2021-10-19 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
US11180517B2 (en) 2017-10-09 2021-11-23 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
US11447510B2 (en) 2017-10-09 2022-09-20 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
US11505564B2 (en) 2017-10-09 2022-11-22 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
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US11629159B2 (en) 2017-10-09 2023-04-18 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
US11939346B2 (en) 2017-10-09 2024-03-26 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
US10519175B2 (en) 2017-10-09 2019-12-31 Compass Pathways Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
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Application publication date: 20181009