CN1082364C - Skin nutritious agent - Google Patents
Skin nutritious agent Download PDFInfo
- Publication number
- CN1082364C CN1082364C CN98115701A CN98115701A CN1082364C CN 1082364 C CN1082364 C CN 1082364C CN 98115701 A CN98115701 A CN 98115701A CN 98115701 A CN98115701 A CN 98115701A CN 1082364 C CN1082364 C CN 1082364C
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- CN
- China
- Prior art keywords
- skin
- cells
- nourishing agent
- cell
- experiment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 235000008935 nutritious Nutrition 0.000 title claims description 12
- 239000003795 chemical substances by application Substances 0.000 claims description 11
- 241000628997 Flos Species 0.000 claims description 5
- 239000009636 Huang Qi Substances 0.000 claims description 5
- 239000000463 material Substances 0.000 claims 1
- 210000003491 skin Anatomy 0.000 abstract description 23
- 210000004027 cell Anatomy 0.000 abstract description 12
- 210000004927 skin cell Anatomy 0.000 abstract description 7
- 230000000694 effects Effects 0.000 abstract description 5
- 230000005855 radiation Effects 0.000 abstract description 5
- 230000012010 growth Effects 0.000 abstract description 3
- 230000032683 aging Effects 0.000 abstract description 2
- 238000000338 in vitro Methods 0.000 abstract description 2
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 241001061264 Astragalus Species 0.000 abstract 1
- 235000010110 Astragalus glycyphyllos Nutrition 0.000 abstract 1
- 235000007516 Chrysanthemum Nutrition 0.000 abstract 1
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 abstract 1
- 244000189548 Chrysanthemum x morifolium Species 0.000 abstract 1
- 241001523681 Dendrobium Species 0.000 abstract 1
- 240000007890 Leonurus cardiaca Species 0.000 abstract 1
- 235000000802 Leonurus cardiaca ssp. villosus Nutrition 0.000 abstract 1
- 240000007164 Salvia officinalis Species 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 238000004113 cell culture Methods 0.000 abstract 1
- 230000002503 metabolic effect Effects 0.000 abstract 1
- 235000005412 red sage Nutrition 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 description 8
- 239000007788 liquid Substances 0.000 description 7
- 210000002615 epidermis Anatomy 0.000 description 5
- 239000006285 cell suspension Substances 0.000 description 4
- 210000001339 epidermal cell Anatomy 0.000 description 4
- 150000002632 lipids Chemical class 0.000 description 3
- 239000012528 membrane Substances 0.000 description 3
- 150000003254 radicals Chemical class 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- WSMYVTOQOOLQHP-UHFFFAOYSA-N Malondialdehyde Chemical compound O=CCC=O WSMYVTOQOOLQHP-UHFFFAOYSA-N 0.000 description 2
- 230000003712 anti-aging effect Effects 0.000 description 2
- 230000002779 inactivation Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 1
- 230000032677 cell aging Effects 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- -1 frost Substances 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000007102 metabolic function Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000004223 radioprotective effect Effects 0.000 description 1
- 238000009666 routine test Methods 0.000 description 1
- 239000002893 slag Substances 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The present invention relates to a skin nourishing agent which is prepared from dendrobium, motherwort, chrysanthemum, milkvetch root, red sage root and honeysuckle stem. The results of percutaneous experiment, cell culture experiment in vitro and radiation resisting experiment indicate that the molecular weight of the skin nourishing agent is small; the skin nourishing agent can quickly penetrate skin cells, accelerate the division growth of skin cells, prolong cell life, and improve the vitality of self antioxidase SOD in cells and the radiation damage preventing capacity of cells; consequently, the metabolic capability of the skin is integrally improved, and the skin nourishing agent has obvious aging resisting effects.
Description
The present invention relates to a kind of skin nutritious agent.
The main purpose of skin care is the process of delaying decrepitude of skin, according to defying age Study on Theory result, the essential measure of delaying decrepitude of skin is the excessive free radical of removing in the Skin Cell, because antioxidase SOD has the effect of eliminating ultra-oxygen anion free radical, therefore, promptly become key component in some skin nutritious agents at SOD several years ago, but, the actual result that uses shows, directly using SOD at skin surface is the effect that can not reach delaying decrepitude of skin, and its reason has three, first SOD is a pheron, molecular weight is more than 30,000 dalton, and penetrating power is poor, can not initiatively be drawn by Skin Cell; Its two be SOD as a kind of pheron, inactivation very easily under external environment be difficult to preserve, and the SOD of inactivation not only can not be eliminated the peroxidating that free radical can aggravate membrane lipid on the contrary; Though it three is to add penetration promoter can help SOD to enter cell, penetration promoter itself can cause the generation of free radical, so the road is obstructed again.
The purpose of this invention is to provide the skin nutritious agent that a kind of anti-aging effects is showing.
The component of this skin nutritious agent and proportioning by weight thereof are: Herba Dendrobii 10-20%, Herba Leonuri 15-25%, Flos Chrysanthemi 5-15%, Radix Astragali 10-20%, Radix Salviae Miltiorrhizae 20-30%, Caulis Lonicerae 10-20%.
Above-mentioned each component is Chinese crude drug, connects to add the water high pressure after the mixed and decocted 30 minutes, and liquid is got in slagging-off, adds ethanol then and staticly settles 48 hours, removes slag once more to get liquid and filter back gained filtrate and be skin nutritious agent.Add other adjuvant based on this, after related process is handled, can obtain skincare product such as frost, cream, liquid class.
Further illustrate detailed content of the present invention below in conjunction with embodiment.
Present embodiment is introduced the skin nutritious agent of three kinds of prescriptions.
One: Herba Dendrobii 10%, Herba Leonuri 25%, Flos Chrysanthemi 5%, the Radix Astragali 20%, Radix Salviae Miltiorrhizae 20%, Caulis Lonicerae 20%.
Its two: Herba Dendrobii 15%, Herba Leonuri 20%, Flos Chrysanthemi 10%, the Radix Astragali 15%, Radix Salviae Miltiorrhizae 25%, Caulis Lonicerae 15%.
Its three: Herba Dendrobii 20%, Herba Leonuri 15%, Flos Chrysanthemi 15%, the Radix Astragali 10%, Radix Salviae Miltiorrhizae 30%, Caulis Lonicerae 10%.
After measured, skin nutritious agent of the present invention is a small-molecule substance, its molecular weight is 250-350 dalton, in order to prove its maintenance skin, to resist old and feeble special-effect, has carried out three routine tests with the skin nutritious agent of above-mentioned second kind of prescription as reagent solution.
One, transdermal test.Consequently reagent solution began at 1.5 hours to see through transdermal device, and transit dose is with proportional relation of time.
Two, the In vitro culture of human body skin epidermis cell test.Consequently reagent solution seemed fairly obvious to the facilitation of skin surface cell growth after 15 days, the speed of growth that the speed of growth of the epidermis cell that reagent solution is cultivated during by 30 days has been compared the epidermis cell of cultivating according to liquid exceeds one times, in addition, epidermis cell in the contrast liquid began old and feeble gradually later at 35 days, and the epidermis cell in the reagent solution just began aging gradually later at 85 days.
Three, the radioprotective test, the epiderm skin cell can cause the increase of snperoxiaized aggravation of membrane lipid and lipofuscin in the environment of roentgenization, this is the sign of cell ageing, according to being added with the mensuration and the comparison of malonaldehyde (the snperoxiaized end product of membrane lipid) and lipofuscin in reagent solution and the contrast epidermal cell suspension that was subjected to radiation gamma of liquid and the shadow bubble suspension respectively, show that reagent solution can obviously suppress the increase of caused malonaldehyde of radiation and lipofuscin, in addition, values of chemiluminescence to epidermal cell suspension on the biochemiluminescence instrument is measured, and its result shows that the activity of the SOD enzyme in the epidermal cell suspension that is added with reagent solution is apparently higher than the activity that is added with the SOD enzyme in the epidermal cell suspension that contrasts liquid.
This shows, skin nutritious agent molecular weight of the present invention is little, can infiltrate Skin Cell fast, quicken the Skin Cell merisis, prolong cell survival, improve the vigor of the antioxidase SOD of self in the cell, strengthen the ability that cell is resisted radiation damage, therefore improve the metabolic function of skin on the whole, had significant anti-aging effects.
Claims (1)
1, a kind of skin nutritious agent is characterized in that being made by following materials of weight proportions: Herba Dendrobii 10-20%, Herba Leonuri 15-25%, Flos Chrysanthemi 5-15%, Radix Astragali 10-20%, Radix Salviae Miltiorrhizae 20-30%, Caulis Lonicerae 10-20%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98115701A CN1082364C (en) | 1998-06-30 | 1998-06-30 | Skin nutritious agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98115701A CN1082364C (en) | 1998-06-30 | 1998-06-30 | Skin nutritious agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1203075A CN1203075A (en) | 1998-12-30 |
| CN1082364C true CN1082364C (en) | 2002-04-10 |
Family
ID=5224682
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN98115701A Expired - Fee Related CN1082364C (en) | 1998-06-30 | 1998-06-30 | Skin nutritious agent |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1082364C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012003768A1 (en) * | 2010-07-05 | 2012-01-12 | Ma Jianzhong | Semen cassiae soft capsule for reducing fat and losing weight and preparation method thereof |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9192643B2 (en) * | 2011-09-14 | 2015-11-24 | Nefeli Corp. | Herbal skin care composition |
| CN103550099A (en) * | 2013-11-06 | 2014-02-05 | 刘凤琪 | Anti-fatigue mask and preparation method |
| CN105395406B (en) * | 2015-12-01 | 2019-01-22 | 青岛中皓生物工程有限公司 | The anti-aging Essence of nourishing and the anti-aging cosmetics of nourishing based on Chinese herbal medicine |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1082886A (en) * | 1992-12-19 | 1994-03-02 | 管遵信 | A kind of Chinese medicine beautifying liquid and production method thereof |
| CN1107693A (en) * | 1994-03-02 | 1995-09-06 | 赵新胜 | "Huaerfu" natural health bath lotion and its preparation |
| CN1113757A (en) * | 1994-06-24 | 1995-12-27 | 王儒新 | Sexual function improving agent and its preparing method |
-
1998
- 1998-06-30 CN CN98115701A patent/CN1082364C/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1082886A (en) * | 1992-12-19 | 1994-03-02 | 管遵信 | A kind of Chinese medicine beautifying liquid and production method thereof |
| CN1107693A (en) * | 1994-03-02 | 1995-09-06 | 赵新胜 | "Huaerfu" natural health bath lotion and its preparation |
| CN1113757A (en) * | 1994-06-24 | 1995-12-27 | 王儒新 | Sexual function improving agent and its preparing method |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012003768A1 (en) * | 2010-07-05 | 2012-01-12 | Ma Jianzhong | Semen cassiae soft capsule for reducing fat and losing weight and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1203075A (en) | 1998-12-30 |
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| C14 | Grant of patent or utility model | ||
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Addressee: Liu Yandao Document name: payment instructions |
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| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |