CN107998461A - A kind of sheath that is exclusively used in has the function of the soluble oil of composite antibacterial - Google Patents
A kind of sheath that is exclusively used in has the function of the soluble oil of composite antibacterial Download PDFInfo
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- CN107998461A CN107998461A CN201711143576.3A CN201711143576A CN107998461A CN 107998461 A CN107998461 A CN 107998461A CN 201711143576 A CN201711143576 A CN 201711143576A CN 107998461 A CN107998461 A CN 107998461A
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- Prior art keywords
- extracting solution
- sheath
- function
- exclusively used
- soluble oil
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- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 26
- 239000002131 composite material Substances 0.000 title claims abstract description 24
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 21
- 239000007788 liquid Substances 0.000 claims abstract description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 13
- 244000144927 Aloe barbadensis Species 0.000 claims abstract description 11
- 235000002961 Aloe barbadensis Nutrition 0.000 claims abstract description 11
- 235000007866 Chamaemelum nobile Nutrition 0.000 claims abstract description 11
- 244000042664 Matricaria chamomilla Species 0.000 claims abstract description 11
- 235000007232 Matricaria chamomilla Nutrition 0.000 claims abstract description 11
- 241000241413 Propolis Species 0.000 claims abstract description 11
- 235000011399 aloe vera Nutrition 0.000 claims abstract description 11
- 230000000845 anti-microbial effect Effects 0.000 claims abstract description 11
- 239000012530 fluid Substances 0.000 claims abstract description 11
- 229940069949 propolis Drugs 0.000 claims abstract description 11
- PQUXFUBNSYCQAL-UHFFFAOYSA-N 1-(2,3-difluorophenyl)ethanone Chemical compound CC(=O)C1=CC=CC(F)=C1F PQUXFUBNSYCQAL-UHFFFAOYSA-N 0.000 claims abstract description 10
- 229920002683 Glycosaminoglycan Polymers 0.000 claims abstract description 10
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims abstract description 10
- 235000011187 glycerol Nutrition 0.000 claims abstract description 10
- 229920001519 homopolymer Polymers 0.000 claims abstract description 10
- 229920002521 macromolecule Polymers 0.000 claims abstract description 10
- 239000003755 preservative agent Substances 0.000 claims abstract description 10
- 230000002335 preservative effect Effects 0.000 claims abstract description 10
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical class CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 claims abstract description 10
- 229940064064 purslane extract Drugs 0.000 claims abstract description 10
- 229910052709 silver Inorganic materials 0.000 claims abstract description 10
- 239000004332 silver Substances 0.000 claims abstract description 10
- 229940047670 sodium acrylate Drugs 0.000 claims abstract description 10
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims abstract description 9
- 229920002125 Sokalan® Polymers 0.000 claims abstract description 9
- 229960001631 carbomer Drugs 0.000 claims abstract description 9
- 239000001301 oxygen Substances 0.000 claims abstract description 9
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 9
- 239000008367 deionised water Substances 0.000 claims abstract description 8
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 8
- 239000001856 Ethyl cellulose Substances 0.000 claims abstract description 7
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims abstract description 7
- 235000019325 ethyl cellulose Nutrition 0.000 claims abstract description 7
- 229920001249 ethyl cellulose Polymers 0.000 claims abstract description 7
- 241000628997 Flos Species 0.000 claims abstract description 4
- 230000006870 function Effects 0.000 claims description 29
- 241000205585 Aquilegia canadensis Species 0.000 claims description 7
- 238000003756 stirring Methods 0.000 claims description 4
- 230000008961 swelling Effects 0.000 claims description 2
- 244000234609 Portulaca oleracea Species 0.000 claims 1
- 235000001855 Portulaca oleracea Nutrition 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 241000894006 Bacteria Species 0.000 abstract description 21
- 210000001215 vagina Anatomy 0.000 abstract description 13
- 241000196324 Embryophyta Species 0.000 abstract description 6
- 230000003110 anti-inflammatory effect Effects 0.000 abstract description 6
- 244000005700 microbiome Species 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 5
- 239000003921 oil Substances 0.000 description 26
- 239000000243 solution Substances 0.000 description 26
- 230000008901 benefit Effects 0.000 description 14
- 206010046914 Vaginal infection Diseases 0.000 description 8
- 201000008100 Vaginitis Diseases 0.000 description 8
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 8
- 241000193830 Bacillus <bacterium> Species 0.000 description 6
- 239000000314 lubricant Substances 0.000 description 6
- 239000002480 mineral oil Substances 0.000 description 6
- 235000010446 mineral oil Nutrition 0.000 description 6
- 230000009286 beneficial effect Effects 0.000 description 5
- 229920002545 silicone oil Polymers 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 241000222122 Candida albicans Species 0.000 description 4
- 241000588724 Escherichia coli Species 0.000 description 4
- 229940095731 candida albicans Drugs 0.000 description 4
- 230000002254 contraceptive effect Effects 0.000 description 4
- 238000000605 extraction Methods 0.000 description 4
- 235000014655 lactic acid Nutrition 0.000 description 4
- 239000004310 lactic acid Substances 0.000 description 4
- 244000052769 pathogen Species 0.000 description 4
- 230000001717 pathogenic effect Effects 0.000 description 4
- 206010061218 Inflammation Diseases 0.000 description 3
- 241000700605 Viruses Species 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 230000003670 easy-to-clean Effects 0.000 description 3
- 230000003628 erosive effect Effects 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 210000004877 mucosa Anatomy 0.000 description 3
- 239000000934 spermatocidal agent Substances 0.000 description 3
- 208000004926 Bacterial Vaginosis Diseases 0.000 description 2
- 229920002527 Glycogen Polymers 0.000 description 2
- 206010067482 No adverse event Diseases 0.000 description 2
- 241000700159 Rattus Species 0.000 description 2
- 206010070834 Sensitisation Diseases 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 229920002678 cellulose Polymers 0.000 description 2
- 239000001913 cellulose Substances 0.000 description 2
- 230000007123 defense Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 229940096919 glycogen Drugs 0.000 description 2
- 239000004519 grease Substances 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 210000004400 mucous membrane Anatomy 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 230000008313 sensitization Effects 0.000 description 2
- 208000030507 AIDS Diseases 0.000 description 1
- 244000043261 Hevea brasiliensis Species 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 241000186660 Lactobacillus Species 0.000 description 1
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 241000224526 Trichomonas Species 0.000 description 1
- 208000006374 Uterine Cervicitis Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 206010008323 cervicitis Diseases 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 239000003433 contraceptive agent Substances 0.000 description 1
- 230000008260 defense mechanism Effects 0.000 description 1
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 210000002919 epithelial cell Anatomy 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000004996 female reproductive system Anatomy 0.000 description 1
- 230000001408 fungistatic effect Effects 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 229940039696 lactobacillus Drugs 0.000 description 1
- 239000004816 latex Substances 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- 201000005630 leukorrhea Diseases 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000005461 lubrication Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 1
- 235000019796 monopotassium phosphate Nutrition 0.000 description 1
- 230000037125 natural defense Effects 0.000 description 1
- 229920003052 natural elastomer Polymers 0.000 description 1
- 229920001194 natural rubber Polymers 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 230000024241 parasitism Effects 0.000 description 1
- PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 description 1
- 230000004962 physiological condition Effects 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000009933 reproductive health Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 210000004999 sex organ Anatomy 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 241001148471 unidentified anaerobic bacterium Species 0.000 description 1
- 210000003708 urethra Anatomy 0.000 description 1
- 206010046901 vaginal discharge Diseases 0.000 description 1
- 210000003905 vulva Anatomy 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/082—Inorganic materials
- A61L31/088—Other specific inorganic materials not covered by A61L31/084 or A61L31/086
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
- A61L2300/104—Silver, e.g. silver sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/452—Lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
The object of the present invention is to provide a kind of sheath that is exclusively used in have the function of the soluble oil of composite antibacterial, the factor is nourished containing the composite antibacterial factor and plant, with good anti-inflammatory, bacteria resistance function, it can effectively adsorb and suppress vagina microorganism, clean vagina, the factor is nourished containing plant at the same time, splendid nourishing effect is played to tender and lovely skin.A kind of sheath that is exclusively used in of the present invention has the function of the soluble oil of composite antibacterial, is prepared using following percentage by weight：Nanometer silver complex antimicrobial fluid 0.5~5%, frutus cnidii extracting solution 1~10%, Radix Sophorae Flavescentis extractive liquid 1~10%, propolis extract 1~10%, Flos Lonicerae extractive solution 1~10%, Radix Et Rhizoma Rhei extract 1~10%, aloe barbadensis Miller extracting solution 1~5%, Purslane extract 1~5%, chamomile extracting solution 1~5%, glycerine 2~10%, propane diols 2 10%, preservative 0.1~1%, macromolecule mucopolysaccharide 0.1~2.0%, carbomer 0~1%, 2~sodium acrylate homopolymer 0~1%, hydrogen-oxygen ethyl cellulose 0~2%, remaining is sterile deionized water.
Description
Technical field
A kind of sheath that is exclusively used in has the function of the soluble oil of composite antibacterial, belongs to medicine or hygiene material
Technical field.
Background technology
Sheath be using extremely extensive contraceptive device and the effective tool that prevents AIDS, be a kind of Year's consumption very
Big articles for daily use, exploitation condom have good practical value and economic benefit.
Existing sheath all adds lubricant substantially, the grease series lubricant agent that a kind of is silicone oil or mineral oil is representative,
Another kind is soluble oil.The most of sheath sold on the market is all that addition silicone oil and mineral oil are used as lubricant
, silicone oil and mineral oil are greasy, it is not easy to clean, for a long time using can also trigger gynecological disease.In clinic it has also been found that：Often
Using the female vagina of sheath contraception, cervicitis chance of occurrence with regard to more.Under normal circumstances, it is aerobic also to have some for vagina
Bacterium and anaerobic bacteria, one balance of formation between them, one defense mechanism of self-assembling formation, there is self purification, vaginal fluid energy
Many pathogenic bacteria are all ejected.However, the fat residue of condom is inherently not easily decomposed and arranges in vagina, these greases
Go out, so that the germ for making some harmful is difficult to exhaust, when these grease long-term existence are in intravaginal, the acidity in vagina can be destroyed
Environment and immune system so that germ is more easy to grow, this is also one of the reason for being increased using women's gynaecological imflammation of sheath,
Frequently gynaecological imflammation may be aggravated using the sheath of silicate-containing oil and mineral oil.Not only property is gentle for soluble oil, to people
Body has no adverse reaction, and subsequent easy to clean, non-greasy, is easily drained noresidue, or can directly be absorbed by the skin.
Vaginitis is the inflammation of connective tissue under vaginal mucosa and mucous membrane, and vaginitis is common gynecological disease.It is normal strong
Health women, due to its anatomy and biochemical characteristics, intrusion of the vagina to pathogen has natural defense function, when vagina from
Right defense function is easy to invade by pathogen when destroying, and causes colpitis.Vaginitis is most common female sex organ
Inflammation, each age level may all be suffered from.Vaginitis is clinically changed with the character of leukorrhea and pruritus vulvue, cusalgia
For major clinical feature, intercourse pain is also common, when urethra is involved in infection, can there is the symptoms such as odynuria, urgent urination.Common vaginitis has
Bacillary, trichomonas, mycotic and senile vahinitis.Clinically bacterial vaginitis is most commonly seen, other types of vagina
Inflammation clinically usually merges bacterium infection.Vaginitis easily recurs after curing, and there are about 5%~10% recurrence rate.Therefore, it is actively pre-
Anti- vaginitis has very important significance including bacterial vaginitis for female reproductive system health.
Sheath raw material is typically use natural rubber or polyurethane, the silicone oil and mineral oil contained by oiliness sheath into
Branch causes the increase of sheath brittleness, or even dissolving latex class sheath.In addition, oily lubricant can damage the system of material of the same race
Product, therefore the sheath of siliceous oil lubricant cannot be used in conjunction with the temperament and interest toy of silicones, in order to avoid damage temperament and interest toy.
The sheath containing antimicrobial component sold currently on the market, while pathogen is killed, while also by lactic acid
Bacillus is almost killed.There are glycogen in the vulva epithelial cell of women, under normal physiological conditions, parasitism has Bacillus acidi lactici.
Glycogen can produce lactic acid under Effect of Lactobacillus, and lactic acid makes private parts that weak acid environment be presented, and acid-base value is 5.5 or so.Lactic acid
Bacillus can play the role of defending pathogenic microorganism invasion, become the natural cover for defense for resisting bacterium together.Bacillus acidi lactici is in the moon
Play a major role during road is self-cleaning, be a kind of microorganism for being beneficial to female reproductive health.The reduction of Bacillus acidi lactici or missing, are destroyed
The self-cleaning function of vagina, causes pathogen amount reproduction to grow, causes gynaecological imflammation.
The technical problem to be solved in the present invention is to provide a kind of sheath containing composite antibacterial function, the sheath is not only
The factor is nourished with contraception function, and with the composite antibacterial factor and plant, there is good anti-inflammatory, bacteria resistance function, it presses down
Bacterium function does not influence beneficial bacterium, mainly suppresses the harmful bacterias such as privates Escherichia coli, Candida albicans and generates, reduction bacterium,
Erosion chance of the harmful microorganisms such as virus to human body；At the same time in this sheath institute with lubricator pH value with women body fluid almost
Unanimously, splendid nourishing effect is played to tender and lovely skin, is not easy to cause allergy, naturally comfortable, collection lubrication, nourish, nursing role
In one, property is gentle, has no adverse reaction to human body, health environment-friendly, subsequent easy to clean, non-greasy, or can be directly by skin
Skin absorbs.
A kind of soluble oil for being exclusively used in sheath and having the function of composite antibacterial of the present invention has lot of advantages.
Advantage one, has good anti-inflammatory, bacteria resistance function, its bacteria resistance function do not influence beneficial bacterium, mainly suppress privates Escherichia coli,
The harmful bacterias such as Candida albicans generate, and reduce the erosion chances of the harmful microorganism to human body such as bacterium, virus；Advantage two, is washed
Net property is good；Advantage three, safe, no sensitization；Advantage four, nourishes the factor containing plant, splendid taste is played to tender and lovely skin
Support effect；Advantage five, can dissolve the spermicide NP.9 of higher concentration, help to play more preferably contraceptive effect；Advantage six, more ring
Protect.
The content of the invention
The purpose of the present invention is for above shortcoming, there is provided a kind of sheath that is exclusively used in has the function of composite antibacterial
Soluble oil, the factor is nourished containing the composite antibacterial factor and plant, has good anti-inflammatory, a bacteria resistance function, while can be with
Effective absorption and suppression vagina microorganism, cleans vagina.One kind of the present invention, which is exclusively used in sheath, has composite antibacterial work(
The soluble oil of energy, is prepared using following percentage by weight：Nanometer silver complex antimicrobial fluid 0.5~5%, frutus cnidii extraction
Liquid 1~10%, Radix Sophorae Flavescentis extractive liquid 1~10%, propolis extract 1~10%, Flos Lonicerae extractive solution 1~10%, Radix Et Rhizoma Rhei extract 1~
10%, aloe barbadensis Miller extracting solution 1~5%, Purslane extract 1~5%, chamomile extracting solution 1~5%, glycerine 2~10%,
Propane diols 2-10%, preservative 0.1~1%, macromolecule mucopolysaccharide 0.1~2.0%, carbomer 0~1%, 2~sodium acrylate homopolymer
0~1%, hydrogen-oxygen ethyl cellulose 0~2%, remaining is sterile deionized water.
A kind of sheath that is exclusively used in of the present invention has the function of the soluble oil of composite antibacterial, it was specifically prepared
Journey is as follows：Enough water is added in a kettle, adds carbomer, 2~sodium acrylate homopolymer, macromolecule under slow stirring
Mucopolysaccharide and hydrogen-oxygen ethyl cellulose, are heated to 80 DEG C, and after 30 minutes, above component complete swelling, is down to room temperature, so
After sequentially add a nanometer silver complex antimicrobial fluid, frutus cnidii extracting solution, Radix Sophorae Flavescentis extractive liquid, propolis extract, Flos Lonicerae extractive solution,
Radix Et Rhizoma Rhei extract, aloe barbadensis Miller extracting solution, Purslane extract, chamomile extracting solution, glycerine, propane diols and preservative,
Stirring is stood after defoaming up to the soluble oil used in sheath for 10 minutes to being uniformly mixed.Condom package envelope
When, in its surface smear or the above-mentioned soluble oil of 0.5~1 gram of injection, then seal.
A kind of sheath that is exclusively used in of the present invention has the advantages that the soluble oil one of composite antibacterial function, has very
Anti-inflammatory well, bacteria resistance function, its bacteria resistance function do not influence beneficial bacterium, mainly suppress privates Escherichia coli, Candida albicans etc.
Harmful bacteria generates, and reduces the erosion chances of the harmful microorganism to human body such as bacterium, virus.Analyze and examine by GB 15979-2002
Surveying a kind of sheath that is exclusively used in of the present invention has the function of the soluble oil of composite antibacterial, can be with from analysis testing result
Find out, it has a stronger bacteriostasis for harmful bacterias such as Escherichia coli, Candida albicans, but to beneficial bacterium Bacillus acidi lactici without
Bacteriostasis.Analysis testing result is shown in Table 1.
1 fungistatic effect of table is tested
Remarks：Neutralizer, potassium dihydrogen phosphate 1.36g, disodium hydrogen phosphate 2.83g, soft phosphatidase 3 .0g, 20.0g Tween 80, distilled water
1000ml。
A kind of sheath that is exclusively used in of the present invention has the advantages that the soluble oil two of composite antibacterial function, detergency
It is good.Soluble oil is dissolved in water, easy cleaning, gently has no sticky, and water-soluble condom is more comfortable, and acidity and viscosity are with human body
Secretion is completely the same, using feeling more harmonious.
A kind of sheath that is exclusively used in of the present invention has the advantages that the soluble oil three of composite antibacterial function, security
Height, no sensitization.Soluble oil easily decomposes in vivo, reduces the danger for inducing women inflammation.According to GB 15979-2002
《Disposable Sanitary Accessory sanitary standard》With《Disinfection technology standard》2008 editions, with SPF grades of SD rats, 8/group carry out cloudy
Road mucous membrane experiment.Vagina mucosa result of the test shows that a kind of sheath that is exclusively used in of the present invention has the function of composite antibacterial
Soluble oil is nonirritant to mouse vaginal mucosa irritation intensity.Analysis testing result is shown in Table 2.
2 tested material of table is to rat vagina mucomembranous irritant test reaction result
A kind of sheath that is exclusively used in of the present invention has the advantages that the soluble oil four of composite antibacterial function, is grown containing plant
The factor is supported, splendid nourishing effect is played to tender and lovely skin.Frutus cnidii extracting solution, Radix Sophorae Flavescentis extractive liquid, propolis extract, honeysuckle
Extracting solution, Radix Et Rhizoma Rhei extract, aloe barbadensis Miller extracting solution, Purslane extract and chamomile extracting solution not only have good antibacterial
Anti-inflammatory effect, while can nourish and nurse well tender and lovely skin.
A kind of sheath that is exclusively used in of the present invention has the advantages that the soluble oil five of composite antibacterial function, can dissolve
The spermicide NP.9 of higher concentration, helps to play more preferably contraceptive effect.Because spermicide NP.9 is water miscible, it is in silicon
Dissolubility very little in oil or mineral oil, thus it is difficult to which addition, can not play contraceptive effect in oily lubricant.
A kind of sheath that is exclusively used in of the present invention has the advantages that the soluble oil six of composite antibacterial function, more ring
Protect.Silicone oil non-degradable, soluble oil then can be absorbed by the body and degrade, and soluble oil sheath belongs to environmentally friendly production
Product, meet international trend.
A kind of sheath that is exclusively used in of the present invention has the function of the soluble oil of composite antibacterial, includes but not limited to
Condom and female condom, further include condom, oral sex sleeve etc..
Embodiment
It is below the embodiment of the present invention.
Embodiment 1
Nanometer silver complex antimicrobial fluid 3%, frutus cnidii extracting solution 2%, Radix Sophorae Flavescentis extractive liquid 5%, propolis extract 5%, honeysuckle extraction
Liquid 5%, Radix Et Rhizoma Rhei extract 2%, aloe barbadensis Miller extracting solution 2%, Purslane extract 2%, chamomile extracting solution 2%, glycerine 5%,
Propane diols 5%, preservative 0.5%, macromolecule mucopolysaccharide 1%, carbomer 0.2%, 2~sodium acrylate homopolymer 0.01%, hydrogen-oxygen ethyl
Cellulose 0.2%, remaining is sterile deionized water.
Embodiment 2
Nanometer silver complex antimicrobial fluid 1%, frutus cnidii extracting solution 1%, Radix Sophorae Flavescentis extractive liquid 3%, propolis extract 3%, honeysuckle extraction
Liquid 8%, Radix Et Rhizoma Rhei extract 3%, aloe barbadensis Miller extracting solution 3%, Purslane extract 5%, chamomile extracting solution 1%, glycerine 6%,
Propane diols 2%, preservative 0.1%, macromolecule mucopolysaccharide 0.5%, carbomer 0.1%, 2~sodium acrylate homopolymer 0.1%, hydrogen-oxygen second
Base cellulose 0.3%, remaining is sterile deionized water.
Embodiment 3
Nanometer silver complex antimicrobial fluid 0.5%, frutus cnidii extracting solution 1%, Radix Sophorae Flavescentis extractive liquid 2%, propolis extract 10%, honeysuckle carries
Take liquid 10%, Radix Et Rhizoma Rhei extract 2%, aloe barbadensis Miller extracting solution 1%, Purslane extract 3%, chamomile extracting solution 5%, glycerine
2%, propane diols 10%, preservative 1%, macromolecule mucopolysaccharide 2.0%, carbomer 0.1%, 2~sodium acrylate homopolymer 0.1%, remaining
For sterile deionized water.
Embodiment 4
Nanometer silver complex antimicrobial fluid 5%, frutus cnidii extracting solution 8%, Radix Sophorae Flavescentis extractive liquid 2%, propolis extract 1%, honeysuckle extraction
Liquid 10%, Radix Et Rhizoma Rhei extract 1%, aloe barbadensis Miller extracting solution 2%, Purslane extract 5%, chamomile extracting solution 1%, glycerine 5%
, propane diols 8%, preservative 0.1~1%, macromolecule mucopolysaccharide 0.1%, 2~sodium acrylate homopolymer 0.1%, hydrogen-oxygen ethyl cellulose
Element 0.5%, remaining is sterile deionized water.
Embodiment 5
Nanometer silver complex antimicrobial fluid 0.5%, frutus cnidii extracting solution 10%, Radix Sophorae Flavescentis extractive liquid 8%, propolis extract 2%, honeysuckle carries
Take liquid 5%, Radix Et Rhizoma Rhei extract 5%, aloe barbadensis Miller extracting solution 1%, Purslane extract 1%, chamomile extracting solution 2%, glycerine 3%
, propane diols 9%, preservative 0.1%, macromolecule mucopolysaccharide 0.2%, carbomer 0.1%, 2~sodium acrylate homopolymer 0.1%, hydrogen-oxygen second
Base cellulose 0.2%, remaining is sterile deionized water.
Five specific embodiments of the present invention are above are only, but the design concept of the present invention is not limited thereto, it is every
Any modification, equivalent variations and the modification that technical spirit according to the present invention makes embodiments above belong to skill of the present invention
The scope of art scheme.
Claims (2)
1. a kind of sheath that is exclusively used in has the function of the soluble oil of composite antibacterial, it is characterised in that uses following weight
Percentage is prepared：Nanometer silver complex antimicrobial fluid 0.5~5%, frutus cnidii extracting solution 1~10%, Radix Sophorae Flavescentis extractive liquid 1~10%, propolis
Extracting solution 1~10%, Flos Lonicerae extractive solution 1~10%, Radix Et Rhizoma Rhei extract 1~10%, aloe barbadensis Miller extracting solution 1~5%, purslane
Extracting solution 1~5%, chamomile extracting solution 1~5%, glycerine 2~10%, propane diols 2-10%, preservative 0.1~1%, macromolecule
Mucopolysaccharide 0.1~2.0%, carbomer 0~1%, 2~sodium acrylate homopolymer 0~1%, hydrogen-oxygen ethyl cellulose 0~2%, remaining is
Sterile deionized water.
2. a kind of sheath that is exclusively used in described in has the function of the soluble oil of composite antibacterial, it is characterised in that its is specific
Preparation process is as follows：Add enough water in a kettle, under slow stirring add carbomer, 2~sodium acrylate homopolymer,
Macromolecule mucopolysaccharide and hydrogen-oxygen ethyl cellulose, are heated to 80 DEG C, and after 30 minutes, above component complete swelling, is down to
Room temperature, then sequentially adds a nanometer silver complex antimicrobial fluid, frutus cnidii extracting solution, Radix Sophorae Flavescentis extractive liquid, propolis extract, honeysuckle
Extracting solution, Radix Et Rhizoma Rhei extract, aloe barbadensis Miller extracting solution, Purslane extract, chamomile extracting solution, glycerine, propane diols and
Preservative, stirs 10 minutes to being uniformly mixed, and stands and is exclusively used in sheath with compound after defoaming up to one kind of the present invention
The soluble oil of antibacterial functions.
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| CN201711143576.3A CN107998461A (en) | 2017-11-17 | 2017-11-17 | A kind of sheath that is exclusively used in has the function of the soluble oil of composite antibacterial |
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| CN201711143576.3A CN107998461A (en) | 2017-11-17 | 2017-11-17 | A kind of sheath that is exclusively used in has the function of the soluble oil of composite antibacterial |
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| CN107998461A true CN107998461A (en) | 2018-05-08 |
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Cited By (5)
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| CN110279511A (en) * | 2019-07-30 | 2019-09-27 | 湖南优感觉生物科技有限公司 | It is a kind of to facilitate the sheath that environment maintains in vagina |
| CN110638746A (en) * | 2019-09-10 | 2020-01-03 | 湖南莱博赛医用机器人有限公司 | Antibacterial and bacteriostatic hydrogel, preparation method thereof and condom |
| CN110664918A (en) * | 2019-11-11 | 2020-01-10 | 欧迪玛(湖北)生物科技有限公司 | Conjunctival agent for preventing sperms from entering uterus and preparation method thereof |
| CN110693982A (en) * | 2019-11-11 | 2020-01-17 | 欧迪玛(湖北)生物科技有限公司 | Gel for preventing sperm and ovum from combining |
| GB2604189A (en) * | 2021-02-10 | 2022-08-31 | Reckitt Benckiser Health Ltd | Packaged lubricated condom |
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| CN110664918A (en) * | 2019-11-11 | 2020-01-10 | 欧迪玛(湖北)生物科技有限公司 | Conjunctival agent for preventing sperms from entering uterus and preparation method thereof |
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Application publication date: 20180508 |