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CN107374645A - A kind of non-invasive blood sugar instrument - Google Patents

A kind of non-invasive blood sugar instrument Download PDF

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Publication number
CN107374645A
CN107374645A CN201610315643.4A CN201610315643A CN107374645A CN 107374645 A CN107374645 A CN 107374645A CN 201610315643 A CN201610315643 A CN 201610315643A CN 107374645 A CN107374645 A CN 107374645A
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CN
China
Prior art keywords
function trough
fixedly connected
blood sugar
main casing
module
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610315643.4A
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Chinese (zh)
Inventor
徐磊
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tai'an Kang Yu Medical Devices Co Ltd
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Tai'an Kang Yu Medical Devices Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tai'an Kang Yu Medical Devices Co Ltd filed Critical Tai'an Kang Yu Medical Devices Co Ltd
Priority to CN201610315643.4A priority Critical patent/CN107374645A/en
Publication of CN107374645A publication Critical patent/CN107374645A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1477Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means non-invasive

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Optics & Photonics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

The present invention relates to blood sugar test technical field, especially a kind of non-invasive blood sugar instrument, including main casing, main casing side offers the standing groove for placing ear-lobe, standing groove left surface offers the first function trough, standing groove right flank offers the second function trough, and LED, optical fiber and luminous lens are fixedly connected with inside the first function trough, are fixedly connected with inside the second function trough into optical lens and sensor assembly.A kind of non-invasive blood sugar instrument of the present invention by opening up the 3rd function trough of the first function trough with LED, the second function trough with sensor assembly and implication sensor respectively inside standing groove, detected jointly by Through Several Survey Measure, lift accuracy of detection, reduce detection difficulty, convenient operation, compact, it is convenient for carrying.

Description

A kind of non-invasive blood sugar instrument
Technical field
The present invention relates to blood sugar test technical field, especially a kind of non-invasive blood sugar instrument.
Background technology
With the lifting of people's living condition, diabetes have turned into a kind of high disease of the incidence of disease.According to investigations, China has been There is nearly 100,000,000 people to suffer from diabetes, and this numeral is also in ascendant trend.Traditional blood sugar detecting method has a protrusion The characteristics of, it is necessary to blood samples of patients is obtained, easily triggers bacterium infection in detection process, causes complication.Then, this area skill Art personnel have done many researchs in terms of noninvasive dynamics monitoring, typical Noninvasive Blood Glucose Detection Methods include near infrared spectrum, in Inspection be present in the optical means such as far-infrared spectrum, Raman spectrum, optoacoustic spectroscopy, light scattering, polarised light, still, these above-mentioned methods Survey that sensitivity is low, and equipment or method are excessively complicated, various people's individual difference is big etc. causes blood sugar test numerical error very big.
The content of the invention
The technical problem to be solved in the present invention is:In order to solve problem present in above-mentioned background technology, there is provided Yi Zhonggai The non-invasive blood sugar instrument entered, it is low to solve current non-invasive blood-sugar detecting instrument detection sensitivity, and detection mode is complicated, and error is big to ask Topic.
The technical solution adopted for the present invention to solve the technical problems is:A kind of non-invasive blood sugar instrument, including main casing, it is described Main casing side offer standing groove for placing ear-lobe, described standing groove left surface offers the first function trough, institute The standing groove right flank stated offers the second function trough, and LED, optical fiber are fixedly connected with inside the first described function trough and is gone out Optical lens, it is fixedly connected with into optical lens and sensor assembly inside the second described function trough, described main casing lateral wall The installation fixing groove being connected with the second function trough is offered, company is fixed in nearly outer openings position inside described installation fixing groove LCD display is connected to, described main casing medial surface offers the 3rd function trough, is fixedly connected inside the 3rd described function trough There is implication sensor, described sensor assembly includes near infrared spectrum module and electrochemical module, described installation fixing groove Inside is fixedly connected with MCU module, and described main casing lower end is fixedly connected with joystick, and described joystick inside is solid Surely it is connected with for the detachable power supply to LED, LCD display and MCU module power supply respectively, outside described joystick The first controlling switch for controlling LED, sensor assembly, LCD display and MCU module is fixedly connected with wall with being used for Second controlling switch of control mouth gas sensor, LCD display and MCU module.
Preferably, passed respectively with implication by signal connecting line in order to facilitate signal acquisition, described MCU module input Sensor, infrared spectrum module and the electrical connection of electrochemical module output end.
Preferably, shown respectively with LCD by signal connecting line in order to facilitate output signal, described MCU module output end Display screen input electrically connects.
Preferably, control for convenience, the first described controlling switch is identical with the second controlling switch size.
The invention has the advantages that a kind of non-invasive blood sugar instrument of the present invention has by being opened up respectively inside standing groove 3rd function trough of the first function trough of LED, second function trough with sensor assembly and implication sensor, by a variety of Detection mode detects jointly, lifts accuracy of detection, reduces detection difficulty, convenient operation, compact, is convenient for carrying.
Brief description of the drawings
The present invention is further described with reference to the accompanying drawings and examples.
Fig. 1 is the structural representation of the present invention.
Fig. 2 is the connection figure of the present invention.
In figure:1. main casing, 2. standing grooves, 3. first function troughs, 4. second function troughs, 5.LED lamps, 6. optical fiber, 7. go out Optical lens, 8. enter optical lens, and 9. installation fixing grooves, 10.LCD display screens, 11. the 3rd function troughs, 12. implication sensors, 13. is red External spectrum module, 14. electrochemical modules, 15.MCU modules, 16. joysticks, 17. power supplys, 18. first controlling switches, 19. Two controlling switches.
Embodiment
In conjunction with the accompanying drawings, the present invention is further explained in detail.These accompanying drawings are simplified schematic diagram, only with Illustration illustrates the basic structure of the present invention, therefore it only shows the composition relevant with the present invention.
A kind of non-invasive blood sugar instrument shown in Fig. 1 and Fig. 2, including main casing 1, the side of main casing 1 are offered for placing ear Vertical standing groove 2, the left surface of standing groove 2 offer the first function trough 3, and the right flank of standing groove 2 offers the second function trough 4, the LED 5, optical fiber 6 and luminous lens 7 are fixedly connected with inside one function trough 3, entering light is fixedly connected with inside the second function trough 4 Lens 8 and sensor assembly, the lateral wall of main casing 1 offer the installation fixing groove 9 being connected with the second function trough 4, and installation is solid To determine the nearly outer openings position in the inside of groove 9 and be fixedly connected with LCD display 10, the medial surface of main casing 1 offers the 3rd function trough 11, Implication sensor 12 is fixedly connected with inside 3rd function trough 11, sensor assembly includes near infrared spectrum module 13 and electrochemistry Module 14, install and be fixedly connected with MCU module 15 inside fixing groove 9, the lower end of main casing 1 is fixedly connected with joystick 16, control The detachable electricity for being powered respectively to LED 5, LCD display 10 and MCU module 15 is fixedly connected with inside handle 16 processed Source 17, it is fixedly connected with the outer wall of joystick 16 for controlling LED 5, sensor assembly, LCD display 10 and MCU module 15 the first controlling switch 18 and the second controlling switch for control mouth gas sensor 12, LCD display 10 and MCU module 15 19。
Preferably, in order to facilitate signal acquisition, the input of MCU module 15 by signal connecting line respectively with implication sensor 12nd, infrared spectrum module 13 and the electrical connection of the output end of electrochemical module 14, it is preferable that in order to facilitate output signal, MCU module 15 Output end is electrically connected with the input of LCD display 10 respectively by signal connecting line, it is preferable that is controlled for convenience, the first control System switch 18 is identical with the size of the second controlling switch 19, and a kind of non-invasive blood sugar instrument of the invention by opening respectively inside standing groove Setting tool has the first function trough 3 of LED 5, has the second function trough 4 of sensor assembly and the 3rd function of implication sensor 12 Groove 11, detected jointly by Through Several Survey Measure, lift accuracy of detection, reduce detection difficulty, convenient to operate, compact, It is convenient for carrying.
Software flow:Beginning-measurement ear-lobe thickness-measurement saturated oxygen-measurement glucose-formula calculating-Monte Carlo-school Correction data returns.
Near infrared spectrum module:Using near infrared spectrum, using youth-than law, the content of glucose in blood is detected.
Operation principle:Using near-infrared transmittance in ear-lobe two-sided measurement blood glucose, placed respectively in ear-lobe both sides Light source and photodetector.The blood glucose amount in the region is depended on through the near infrared light total amount of ear-lobe.Selection ear-lobe measures Because ear-lobe position does not have bone tissue and compared relatively thin.Need for near-infrared (NIR) illumination to be mapped to the side of ear-lobe simultaneously, And the receiver that opposite side is placed is used for receiving attenuation light, then decay optical signal is sampled and handled.
Light source:Form of light source;LED:Optical source wavelength nm.
1) 560 measurement ear-lobe thickness.
2) 660 measurement blood Hb940 measurement blood HbO2.
3) 1350 measurement blood reclaimed waters 1550 measure blood-glucose.
Electrochemical module;
Principle;Diabetic is consumed with significant quantities of fat, and the ketoboidies content in blood is constantly assembled, and is penetrated into through blood In alveolar, excreted through breathing, tidal air content of acetone is proportionate with blood glucose.Form;Electrification is formed using porphyrin spinning Sensor is learned, content of acetone in implication is detected, as detection variable.
Software formula:
1、
2nd, saturated oxygen;
3rd, glucose
IN=I water/I glucose
4th, Monte Carlo normal state value
Regression correction
It is complete by above-mentioned description, relevant staff using the above-mentioned desirable embodiment according to the present invention as enlightenment Various changes and amendments can be carried out without departing from the scope of the technological thought of the present invention' entirely.The technology of this invention Property scope is not limited to the content on specification, it is necessary to determines its technical scope according to right.

Claims (4)

1. a kind of non-invasive blood sugar instrument, including main casing (1), it is characterized in that:Described main casing (1) side is offered for placing The standing groove (2) of ear-lobe, described standing groove (2) left surface offer the first function trough (3), described standing groove (2) right side Face offers the second function trough (4), and LED (5), optical fiber (6) and light extraction are fixedly connected with inside described the first function trough (3) Lens (7), described the second function trough (4) is internal to be fixedly connected with into optical lens (8) and sensor assembly, described main casing (1) lateral wall offers the installation fixing groove (9) being connected with the second function trough (4), and described installation fixing groove (9) is internal near Outer openings position is fixedly connected with LCD display (10), and described main casing (1) medial surface offers the 3rd function trough (11) implication sensor (12), is fixedly connected with inside the 3rd described function trough (11), described sensor assembly includes near Infrared spectrum module (13) and electrochemical module (14), described installation fixing groove (9) is internal to be fixedly connected with MCU module (15), described main casing (1) lower end is fixedly connected with joystick (16), is fixedly connected inside described joystick (16) Have for the detachable power supply (17) to LED (5), LCD display (10) and MCU module (15) power supply respectively, it is described It is fixedly connected with joystick (16) outer wall for controlling LED (5), sensor assembly, LCD display (10) and MCU moulds The first controlling switch (18) of block (15) is with being used for control mouth gas sensor (12), LCD display (10) and MCU module (15) Second controlling switch (19).
2. a kind of non-invasive blood sugar instrument according to claim 1, it is characterized in that:Described MCU module (15) input passes through Signal connecting line electrically connects with implication sensor (12), infrared spectrum module (13) and electrochemical module (14) output end respectively.
3. a kind of non-invasive blood sugar instrument according to claim 1, it is characterized in that:Described MCU module (15) output end passes through Signal connecting line electrically connects with LCD display (10) input respectively.
4. a kind of non-invasive blood sugar instrument according to claim 1, it is characterized in that:Described the first controlling switch (18) and second Controlling switch (19) size is identical.
CN201610315643.4A 2016-05-16 2016-05-16 A kind of non-invasive blood sugar instrument Pending CN107374645A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610315643.4A CN107374645A (en) 2016-05-16 2016-05-16 A kind of non-invasive blood sugar instrument

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610315643.4A CN107374645A (en) 2016-05-16 2016-05-16 A kind of non-invasive blood sugar instrument

Publications (1)

Publication Number Publication Date
CN107374645A true CN107374645A (en) 2017-11-24

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108968975A (en) * 2018-07-20 2018-12-11 深圳市漫牛医疗有限公司 The measurement method and equipment of blood glucose value based on artificial intelligence
WO2021168721A1 (en) * 2020-02-27 2021-09-02 Shenzhen Xpectvision Technology Co., Ltd. Apparatus for blood sugar level detection
CN116035570A (en) * 2022-04-12 2023-05-02 闽江学院 A stretchable physiological monitor and method for fitting earlobe

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6172743B1 (en) * 1992-10-07 2001-01-09 Chemtrix, Inc. Technique for measuring a blood analyte by non-invasive spectrometry in living tissue
WO2001056454A2 (en) * 2000-02-02 2001-08-09 Healthetech, Inc. Indirect calorimeter for medical applications
US20020026937A1 (en) * 2000-08-28 2002-03-07 Mault James R. Respiratory gas sensors in folw path
US20130253286A1 (en) * 2010-08-27 2013-09-26 The Johns Hopkins University Device and System for Sensing Medically Relevant Information from the Mouth

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6172743B1 (en) * 1992-10-07 2001-01-09 Chemtrix, Inc. Technique for measuring a blood analyte by non-invasive spectrometry in living tissue
WO2001056454A2 (en) * 2000-02-02 2001-08-09 Healthetech, Inc. Indirect calorimeter for medical applications
US20020026937A1 (en) * 2000-08-28 2002-03-07 Mault James R. Respiratory gas sensors in folw path
US20130253286A1 (en) * 2010-08-27 2013-09-26 The Johns Hopkins University Device and System for Sensing Medically Relevant Information from the Mouth

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108968975A (en) * 2018-07-20 2018-12-11 深圳市漫牛医疗有限公司 The measurement method and equipment of blood glucose value based on artificial intelligence
WO2021168721A1 (en) * 2020-02-27 2021-09-02 Shenzhen Xpectvision Technology Co., Ltd. Apparatus for blood sugar level detection
US11617555B2 (en) 2020-02-27 2023-04-04 Shenzhen Xpectvision Technology Co., Ltd. Apparatus for blood sugar level detection
CN116035570A (en) * 2022-04-12 2023-05-02 闽江学院 A stretchable physiological monitor and method for fitting earlobe
CN116035570B (en) * 2022-04-12 2025-01-17 闽江学院 Stretchable physiological monitor attached to earlobe and method thereof

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Application publication date: 20171124