CN107325881A - The extracting process and its cannabis leaf oil product of cannabis leaf oil - Google Patents
The extracting process and its cannabis leaf oil product of cannabis leaf oil Download PDFInfo
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- CN107325881A CN107325881A CN201710631525.9A CN201710631525A CN107325881A CN 107325881 A CN107325881 A CN 107325881A CN 201710631525 A CN201710631525 A CN 201710631525A CN 107325881 A CN107325881 A CN 107325881A
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- 238000000034 method Methods 0.000 title claims abstract description 20
- 230000008569 process Effects 0.000 title claims abstract description 16
- 241000218236 Cannabis Species 0.000 title claims abstract 14
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims abstract description 45
- 238000000605 extraction Methods 0.000 claims abstract description 36
- ZTGXAWYVTLUPDT-UHFFFAOYSA-N cannabidiol Natural products OC1=CC(CCCCC)=CC(O)=C1C1C(C(C)=C)CC=C(C)C1 ZTGXAWYVTLUPDT-UHFFFAOYSA-N 0.000 claims abstract description 33
- QHMBSVQNZZTUGM-UHFFFAOYSA-N Trans-Cannabidiol Natural products OC1=CC(CCCCC)=CC(O)=C1C1C(C(C)=C)CCC(C)=C1 QHMBSVQNZZTUGM-UHFFFAOYSA-N 0.000 claims abstract description 32
- QHMBSVQNZZTUGM-ZWKOTPCHSA-N cannabidiol Chemical compound OC1=CC(CCCCC)=CC(O)=C1[C@H]1[C@H](C(C)=C)CCC(C)=C1 QHMBSVQNZZTUGM-ZWKOTPCHSA-N 0.000 claims abstract description 32
- 229950011318 cannabidiol Drugs 0.000 claims abstract description 32
- 239000000843 powder Substances 0.000 claims abstract description 32
- PCXRACLQFPRCBB-ZWKOTPCHSA-N dihydrocannabidiol Natural products OC1=CC(CCCCC)=CC(O)=C1[C@H]1[C@H](C(C)C)CCC(C)=C1 PCXRACLQFPRCBB-ZWKOTPCHSA-N 0.000 claims abstract description 29
- 244000025254 Cannabis sativa Species 0.000 claims abstract description 22
- 229910002092 carbon dioxide Inorganic materials 0.000 claims abstract description 22
- 239000001569 carbon dioxide Substances 0.000 claims abstract description 22
- 235000012766 Cannabis sativa ssp. sativa var. sativa Nutrition 0.000 claims abstract description 20
- 235000012765 Cannabis sativa ssp. sativa var. spontanea Nutrition 0.000 claims abstract description 20
- 235000009120 camo Nutrition 0.000 claims abstract description 20
- 235000005607 chanvre indien Nutrition 0.000 claims abstract description 20
- 239000011487 hemp Substances 0.000 claims abstract description 20
- 239000002994 raw material Substances 0.000 claims abstract description 14
- 239000007788 liquid Substances 0.000 claims abstract description 12
- 238000000926 separation method Methods 0.000 claims abstract description 6
- 239000002904 solvent Substances 0.000 claims abstract description 6
- 239000002253 acid Substances 0.000 claims description 6
- 125000001931 aliphatic group Chemical group 0.000 claims description 6
- 150000003505 terpenes Chemical class 0.000 claims description 5
- 229960004424 carbon dioxide Drugs 0.000 claims 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 241000790917 Dioxys <bee> Species 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 229910002090 carbon oxide Inorganic materials 0.000 claims 1
- 238000011084 recovery Methods 0.000 abstract description 6
- 240000004308 marijuana Species 0.000 description 34
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 6
- 239000000284 extract Substances 0.000 description 6
- 239000003960 organic solvent Substances 0.000 description 5
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 230000004048 modification Effects 0.000 description 4
- 238000012986 modification Methods 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 230000000903 blocking effect Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000003208 petroleum Substances 0.000 description 2
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- UVOLYTDXHDXWJU-UHFFFAOYSA-N Cannabichromene Chemical compound C1=CC(C)(CCC=C(C)C)OC2=CC(CCCCC)=CC(O)=C21 UVOLYTDXHDXWJU-UHFFFAOYSA-N 0.000 description 1
- UVOLYTDXHDXWJU-NRFANRHFSA-N Cannabichromene Natural products C1=C[C@](C)(CCC=C(C)C)OC2=CC(CCCCC)=CC(O)=C21 UVOLYTDXHDXWJU-NRFANRHFSA-N 0.000 description 1
- WVOLTBSCXRRQFR-SJORKVTESA-N Cannabidiolic acid Natural products OC1=C(C(O)=O)C(CCCCC)=CC(O)=C1[C@@H]1[C@@H](C(C)=C)CCC(C)=C1 WVOLTBSCXRRQFR-SJORKVTESA-N 0.000 description 1
- REOZWEGFPHTFEI-JKSUJKDBSA-N Cannabidivarin Chemical compound OC1=CC(CCC)=CC(O)=C1[C@H]1[C@H](C(C)=C)CCC(C)=C1 REOZWEGFPHTFEI-JKSUJKDBSA-N 0.000 description 1
- 241001471082 Colocasia bobone disease-associated cytorhabdovirus Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 206010027476 Metastases Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000218231 Moraceae Species 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- CYQFCXCEBYINGO-UHFFFAOYSA-N THC Natural products C1=C(C)CCC2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3C21 CYQFCXCEBYINGO-UHFFFAOYSA-N 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000003556 anti-epileptic effect Effects 0.000 description 1
- 230000000561 anti-psychotic effect Effects 0.000 description 1
- 239000001961 anticonvulsive agent Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- WVOLTBSCXRRQFR-DLBZAZTESA-M cannabidiolate Chemical compound OC1=C(C([O-])=O)C(CCCCC)=CC(O)=C1[C@H]1[C@H](C(C)=C)CCC(C)=C1 WVOLTBSCXRRQFR-DLBZAZTESA-M 0.000 description 1
- REOZWEGFPHTFEI-UHFFFAOYSA-N cannabidivarine Natural products OC1=CC(CCC)=CC(O)=C1C1C(C(C)=C)CCC(C)=C1 REOZWEGFPHTFEI-UHFFFAOYSA-N 0.000 description 1
- QXACEHWTBCFNSA-UHFFFAOYSA-N cannabigerol Natural products CCCCCC1=CC(O)=C(CC=C(C)CCC=C(C)C)C(O)=C1 QXACEHWTBCFNSA-UHFFFAOYSA-N 0.000 description 1
- SEEZIOZEUUMJME-FOWTUZBSSA-N cannabigerolic acid Chemical compound CCCCCC1=CC(O)=C(C\C=C(/C)CCC=C(C)C)C(O)=C1C(O)=O SEEZIOZEUUMJME-FOWTUZBSSA-N 0.000 description 1
- SEEZIOZEUUMJME-UHFFFAOYSA-N cannabinerolic acid Natural products CCCCCC1=CC(O)=C(CC=C(C)CCC=C(C)C)C(O)=C1C(O)=O SEEZIOZEUUMJME-UHFFFAOYSA-N 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000009401 metastasis Effects 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 238000012805 post-processing Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- -1 terpene Compound Chemical class 0.000 description 1
- 235000007586 terpenes Nutrition 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B1/00—Production of fats or fatty oils from raw materials
- C11B1/02—Pretreatment
- C11B1/04—Pretreatment of vegetable raw material
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B1/00—Production of fats or fatty oils from raw materials
- C11B1/10—Production of fats or fatty oils from raw materials by extracting
- C11B1/104—Production of fats or fatty oils from raw materials by extracting using super critical gases or vapours
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention discloses a kind of extracting process of cannabis leaf oil, including：Pretreatment：The flower and leaf of hemp are placed under 105 120 degrees Celsius and dried 0.5 4 hours, the raw material A that moisture content is less than 7% is obtained；Crush：Raw material A is crushed to 50 100 mesh, powder B is obtained；Dry：Powder B is placed under 105 120 degrees Celsius and dried 0.5 1 hours, the powder C that moisture content is less than 5% is obtained；Extraction：Supercritical carbon dioxide extracting is carried out to powder C, liquid D and residue E are obtained after extraction；Separation：Liquid D parses cannabidiol through throttling expansion, and is recovered to solvent F.The cannabis leaf oil in hemp is extracted with supercritical carbon dioxide, the recovery rate highest of cannabidiol can reach 90%, and purity is more than 20%.
Description
Technical field
Field is extracted the present invention relates to material, and in particular to extracting process and its cannabis the leaf oil production of cannabis leaf oil
Product.
Background technology
Hemp（Cannabis sativaL.）Also known as fire fiber crops or hemp, are Moraceae, Cannabis plant, annual upright grass
This, it is high 1-3 meters.The cannabidiol contained in hemp（CBD）Composition, is the phenols not yet isolated in other animals and plants at present
Compound, cannabidiol（CBD）It is non-additive composition, with very high medical value.Research shows, if cannabidiol is closed
The application of reason ground medically, then has anti-epileptic, an antipsychotic, anti-melancholy, analgesic, mitigate cancer because of caused by chemotherapy nausea with
And treat the functions such as asthma.Scientist also found cannabidiol in recent years（CBD）It is some many with blocking for powerful antioxidants
Phenol is to the adverse effect of human nerve, and with blocking Metastasis in Breast Cancer, resisting rheumatoid arthritis, anti-insomnia etc. a series of
Physiological active functionses.THC according to contained by hemp（THC）Ratio, it is generally divided into industrial hemp and drugs
The class of hemp two.Industrial hemp belongs to low toxicity hemp, wherein THC（THC）Content not more than 0.3%（Generally acknowledge by various countries
Define method）, without drugs value；And in the leaf of marijuana hemp and spray THC（THC）Content
It is higher, belong to high poison hemp.
Due to the medical value of cannabidiol, built up many extraction factories in the whole world, and prior art extracts big cannabidiol
It is to be extracted using organic solvent extraction mostly, this aspect consumes a large amount of organic solvents, increase extracts cost and to ring
The pollution in border, the organic solvent on the other hand remained in cannabidiol extract can also reduce the product of cannabidiol extract
Matter, so reducing the extracting method pole of production cost while the purity and extraction efficiency of a kind of big cannabidiol extract of raising
To be important.
The content of the invention
It is an object of the invention to provide a kind of extracting process of cannabis leaf oil and its cannabis rich in cannabidiol
Leaf oil product, solves prior art and utilizes solution restricted-access media cannabis leaf oil, consumes a large amount of organic solvents, increase extraction
The problem of wherein cannabidiol quality being reduced while cost and the pollution to environment.
To solve above-mentioned technical problem, the present invention uses following technical scheme：
A kind of extracting process of cannabis leaf oil, including：
Pretreatment：The flower and leaf of hemp are placed under 125-135 degrees Celsius and dried 0.1-0.4 hours, moisture content is obtained and is less than
6% raw material A；
Crush：Raw material A is crushed to 30-45 mesh, powder B is obtained；
Dry：Powder B is placed under 125-135 degrees Celsius and dried 0.2-0.4 hours, the powder C that moisture content is less than 4% is obtained；
Extraction：Supercritical carbon dioxide extracting is carried out to powder C, liquid D and residue E are obtained after extraction；
Separation：Liquid D parses cannabidiol through throttling expansion, and is recovered to solvent F.
The cannabis leaf oil in hemp is extracted using supercritical carbon dioxide, is extracted compared to using organic solvent, it is super to face
The purity of cannabidiol is higher in the cannabis leaf oil that boundary's carbon dioxide draw is obtained, recovery rate is higher, extraction rate is faster, and
The content of active ingredient is also much higher in cannabis leaf oil；Re-used after carbon dioxide can be collected after parsing, even
The partial CO 2 of loss will not also be polluted to operating environment, and carbon dioxide will not be in obtained cannabis leaf oil production
Remained in product.
As preferred, powder C is carried out before supercritical carbon dioxide extracting, powder C is cooled to 18-25 degrees Celsius simultaneously
Its moisture content is kept to be less than 5%.
As preferred, in the extraction step, the temperature of extraction is 30-40 degrees Celsius, pressure is 10-20MPa, extraction
Time is 2-5 hours.
As preferred, in the extraction step, the flow of carbon dioxide is 300-600 kgs/hr.
As preferred, in the separating step, the temperature of parsing is 30-40 degrees Celsius, pressure is 2-10MPa.
As preferred, the cannabis leaf oil parsed in the separating step is heated to after 60 degrees Celsius, is kept for 10 points
More than clock, it is put into homogenizer, the homogeneous rear next step that enters is handled.
As preferred, entrainer is additionally added in the extraction step, the entrainer includes ethyl acetate, industrial naptha
With the one or more in petroleum ether.
Extracted for the cannabis leaf oil in industrial hemp, entrainer, energy between entrainer and thing to be extracted can be used
Extraction efficiency can be improved by enough forming chemical bond, therefore adding entrainer.It is general to use ethyl acetate, industrial naptha and petroleum ether
Deng, entrainer is remarkably improved extraction yield, but can correspondingly cause post-processing difficulty and production cost increase.
As preferred, the entrainer and powder C weight ratio are 0.3-1.0：100.
Entrainer is very few, does not have the effect for improving extraction efficiency, and entrainer consumption is excessive, may be because of solution in parsing
Analysis is insufficient to make entrainer remain in cannabis leaf oil product.
As preferred, reextraction is carried out to residue E, the temperature of the reextraction is 20-50 degrees Celsius, pressure is
5-30MPa, extraction time are 1-5.5 hours, the flow of carbon dioxide is 500-850 kgs/hr.
A kind of cannabis leaf oil, by weight, including cannabidiol 10-20%, unsaturated aliphatic acid 61-68%, terpene
Compound 8-10%.
Much more American-European at present use 30% to 60% cannabis leaf oil for health product raw material, medicinal raw material is sometimes for approaching
99% purity.There is provided the method that cannabidiol is carried at the beginning of one for health-product market by the present invention.The product prepared through this law contains
Cannabidiol composition is 10% to 30%, and remaining main component is unsaturated aliphatic acid, accounts for 50% to 60%.It is simultaneously also other
Nearly 100 of terpenoid, such as CBDA, CBGA, CBDV, CBC, CBN, CBG, THC etc., it is combined and accounts for 9-11% altogether.Its
It is polysaccharide, including the impurity such as albumen and pectin.
Compared with prior art, beneficial effects of the present invention are at least one of following：
1）The cannabis leaf oil in hemp is extracted using supercritical carbon dioxide, the recovery rate highest of wherein cannabidiol can reach
To 90%, purity is more than 20%.
2）The cannabis leaf oil in hemp is extracted using supercritical carbon dioxide, after carbon dioxide can be collected after parsing
Re-use, often extract once, the loss late of carbon dioxide is less than 15%, and the partial CO 2 even lost also will not be right
Operating environment is polluted, and carbon dioxide will not be remained in obtained cannabis leaf oil product.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to
Limit the present invention.
Embodiment 1：
A kind of extracting process of cannabis leaf oil, including：
Pretreatment：The flower and leaf of hemp are placed under 125 degrees Celsius and dried 0.1 hour, moisture content is obtained up to 6% raw material A；
Crush：Raw material A is crushed to 30-35 mesh, powder B is obtained；
Dry：Powder B is placed under 125 degrees Celsius and dried 0.2 hour, moisture content is obtained and is less than 4% powder C, and make powder C
It is cooled to 18 degrees Celsius and keeps its moisture content to be less than 5%；
Extraction：Carry out supercritical carbon dioxide extracting to powder C, the temperature of extraction is 30 degrees Celsius, pressure is 10MPa, extraction
Time is 2 hours, the flow of carbon dioxide is 300 kgs/hr, and liquid D and residue E are obtained after extraction；
Separation：Liquid D temperature be 30 degrees Celsius, pressure is to parse cannabis leaf oil under conditions of 2MPa, and is recovered to molten
Agent F；The cannabis leaf oil parsed is heated to after 60 degrees Celsius, is kept for 10 minutes, is put into homogenizer, homogeneous rear filling or enter
Enter next step processing.
The cannabis leaf oil that the present embodiment is obtained, by weight, including cannabidiol 13.9%, unsaturated aliphatic acid
68.3%th, terpenoid 8.4%.
Embodiment 2：
A kind of extracting process of cannabis leaf oil, including：
Pretreatment：The flower and leaf of hemp are placed under 135 degrees Celsius and dried 0.4 hour, the raw material A of moisture content 4.8% is obtained；
Crush：Raw material A is crushed to 40-45 mesh, powder B is obtained；
Dry：Powder B is placed under 135 degrees Celsius and dried 0.4 hour, the powder C of moisture content 3.6% is obtained, and drops powder C
Temperature is to 25 degrees Celsius and keeps its moisture content 4%；
Extraction：Carry out supercritical carbon dioxide extracting to powder C, the temperature of extraction is 40 degrees Celsius, pressure is 20MPa, extraction
Time is 5 hours, the flow of carbon dioxide is 600 kgs/hr, and liquid D and residue E are obtained after extraction；
Separation：Liquid D temperature be 40 degrees Celsius, pressure is to parse cannabis leaf oil under conditions of 10MPa, and is recovered to molten
Agent F；The cannabis leaf oil parsed is heated to after 60 degrees Celsius, is kept for more than 10 minutes, is put into homogenizer, homogeneous rear filling
Or enter next step processing.
The cannabis leaf oil that the present embodiment is obtained, by weight, including cannabidiol 15.9%, unsaturated aliphatic acid
61.1%th, terpenoid 9.1%.
Embodiment 3：
A kind of extracting process of cannabis leaf oil, including：
Pretreatment：The flower and leaf of hemp are placed under 132 degrees Celsius and dried 0.25 hour, the raw material A of moisture content 5.7% is obtained；
Crush：Raw material A is crushed to 35-40 mesh, powder B is obtained；
Dry：Powder B is placed under 132 degrees Celsius and dried 0.3 hour, moisture content is obtained and is less than 4% powder C, and make powder C
It is cooled to 22 degrees Celsius and keeps its moisture content to be less than 5%；
Extraction：Carry out supercritical carbon dioxide extracting to powder C, the temperature of extraction is 37 degrees Celsius, pressure is 15MPa, extraction
Time is 3.5 hours, the flow of carbon dioxide is 450 kgs/hr, and liquid D and residue E are obtained after extraction；
Separation：Liquid D is that 36 degrees Celsius, pressure are to parse cannabis leaf oil under conditions of 7MPa in temperature, and is recovered to molten
Agent F；The cannabis leaf oil parsed is heated to after 80 degrees Celsius, is kept for more than 10 minutes, is put into homogenizer, homogeneous rear filling
Or enter next step processing.
The cannabis leaf oil that the present embodiment is obtained, by weight, including cannabidiol 19.7%, unsaturated aliphatic acid
65.8%th, terpenoid 9.2%.
Following table show cannabidiol content and solvent in the cannabidiol recovery rate of embodiment 1-3 methods describeds, product
The measurement result of loss late：
| Embodiment | Cannabidiol recovery rate % | Cannabidiol content wt% in product | Solvent loss rate % |
| 1 | 90.6 | 13.9 | 10.7 |
| 2 | 92.4 | 15.9 | 12.2 |
| 3 | 93.2 | 19.7 | 9.0 |
As can be seen from the above table, either cannabidiol content or solvent loss rate side in cannabidiol recovery rate, product
Face considers, is all that embodiment 3 is more excellent.
Although reference be made herein to invention has been described for multiple explanatory embodiments of the invention, however, it is to be understood that
Those skilled in the art can be designed that a lot of other modification and embodiment, and these modifications and embodiment will fall in this Shen
Please be within disclosed spirit and spirit.More specifically, can be to master in the range of disclosure and claim
The building block and/or layout for inscribing composite configuration carry out a variety of variations and modifications.Except what is carried out to building block and/or layout
Outside modification and improvement, to those skilled in the art, other purposes also will be apparent.
Claims (7)
1. a kind of extracting process of cannabis leaf oil, it is characterised in that including：
Pretreatment：The flower and leaf of hemp are placed under 125-135 degrees Celsius and dried 0.1-0.4 hours, moisture content is obtained and is less than
6% raw material A；
Crush：Raw material A is crushed to 30-45 mesh, powder B is obtained；
Dry：Powder B is placed under 125-135 degrees Celsius and dried 0.2-0.4 hours, the powder C that moisture content is less than 4% is obtained；
Extraction：Supercritical carbon dioxide extracting is carried out to powder C, liquid D and residue E are obtained after extraction；
Separation：Liquid D parses cannabis leaf oil through throttling expansion, and is recovered to solvent F.
2. the extracting process of cannabis leaf oil according to claim 1, it is characterised in that overcritical two are carried out to powder C
Before carbonoxide extraction, powder C is cooled to 18-25 degrees Celsius and keep its moisture content to be less than 5%.
3. the extracting process of cannabis leaf oil according to claim 1, it is characterised in that in the extraction step, extraction
Temperature be 30-40 degrees Celsius, pressure be that 10-20MPa, extraction time are 2-5 hours.
4. the extracting process of cannabis leaf oil according to claim 1, it is characterised in that in the extraction step, dioxy
The flow for changing carbon is 300-600 kgs/hr.
5. the extracting process of cannabis leaf oil according to claim 1, it is characterised in that in the separating step, parsing
Temperature be 30-40 degrees Celsius, pressure be 2-10MPa.
6. the extracting process of cannabis leaf oil according to claim 1, it is characterised in that parsed in the separating step
Cannabis leaf oil be heated to after 60 degrees Celsius, keep more than 10 minutes, be put into homogenizer, it is homogeneous after enter next step at
Reason.
7. cannabis leaf oil made from a kind of extracting process of the cannabis leaf oil described in claim 1-6, it is characterised in that press
Weight meter, including cannabidiol 10-20%, unsaturated aliphatic acid 61-68%, terpenoid 8-10%.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710631525.9A CN107325881A (en) | 2017-07-28 | 2017-07-28 | The extracting process and its cannabis leaf oil product of cannabis leaf oil |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710631525.9A CN107325881A (en) | 2017-07-28 | 2017-07-28 | The extracting process and its cannabis leaf oil product of cannabis leaf oil |
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|---|---|
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Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108949363A (en) * | 2018-09-26 | 2018-12-07 | 常德华馥生物技术有限公司 | A kind of Solventless Extraction Process of industrial hemp floral leaf essential oil |
| CN110101804A (en) * | 2019-05-30 | 2019-08-09 | 厦门梓素生物科技有限公司 | A kind of epilepsy drugs combination of the extract containing cannabidiol and preparation method thereof |
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| CN111000897A (en) * | 2019-11-28 | 2020-04-14 | 云南汉木森生物科技有限责任公司 | aerosol |
| CN110872210A (en) * | 2019-12-23 | 2020-03-10 | 大姚麻王科华生物科技有限公司 | Preparation equipment of cannabidiol |
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