CN107216942A - 一种基于牡丹籽的化妆品用油的生产方法 - Google Patents
一种基于牡丹籽的化妆品用油的生产方法 Download PDFInfo
- Publication number
- CN107216942A CN107216942A CN201710250986.1A CN201710250986A CN107216942A CN 107216942 A CN107216942 A CN 107216942A CN 201710250986 A CN201710250986 A CN 201710250986A CN 107216942 A CN107216942 A CN 107216942A
- Authority
- CN
- China
- Prior art keywords
- ethyl acetate
- ethanol
- oil
- peony
- extraction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 241000736199 Paeonia Species 0.000 title claims abstract description 32
- 235000006484 Paeonia officinalis Nutrition 0.000 title claims abstract description 32
- 239000002537 cosmetic Substances 0.000 title claims abstract description 16
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 8
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims abstract description 60
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 42
- 238000000605 extraction Methods 0.000 claims abstract description 25
- QRYRORQUOLYVBU-VBKZILBWSA-N Carnosic acid Natural products CC([C@@H]1CC2)(C)CCC[C@]1(C(O)=O)C1=C2C=C(C(C)C)C(O)=C1O QRYRORQUOLYVBU-VBKZILBWSA-N 0.000 claims abstract description 19
- 108010087806 Carnosine Proteins 0.000 claims abstract description 19
- CQOVPNPJLQNMDC-UHFFFAOYSA-N N-beta-alanyl-L-histidine Natural products NCCC(=O)NC(C(O)=O)CC1=CN=CN1 CQOVPNPJLQNMDC-UHFFFAOYSA-N 0.000 claims abstract description 19
- 229940044199 carnosine Drugs 0.000 claims abstract description 19
- CQOVPNPJLQNMDC-ZETCQYMHSA-N carnosine Chemical compound [NH3+]CCC(=O)N[C@H](C([O-])=O)CC1=CNC=N1 CQOVPNPJLQNMDC-ZETCQYMHSA-N 0.000 claims abstract description 19
- 235000015112 vegetable and seed oil Nutrition 0.000 claims abstract description 19
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 claims abstract description 18
- JEVVKJMRZMXFBT-XWDZUXABSA-N Lycophyll Natural products OC/C(=C/CC/C(=C\C=C\C(=C/C=C/C(=C\C=C\C=C(/C=C/C=C(\C=C\C=C(/CC/C=C(/CO)\C)\C)/C)\C)/C)\C)/C)/C JEVVKJMRZMXFBT-XWDZUXABSA-N 0.000 claims abstract description 18
- 235000012661 lycopene Nutrition 0.000 claims abstract description 18
- 239000001751 lycopene Substances 0.000 claims abstract description 18
- OAIJSZIZWZSQBC-GYZMGTAESA-N lycopene Chemical compound CC(C)=CCC\C(C)=C\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C=C(/C)CCC=C(C)C OAIJSZIZWZSQBC-GYZMGTAESA-N 0.000 claims abstract description 18
- 229960004999 lycopene Drugs 0.000 claims abstract description 18
- ZCIHMQAPACOQHT-ZGMPDRQDSA-N trans-isorenieratene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/c1c(C)ccc(C)c1C)C=CC=C(/C)C=Cc2c(C)ccc(C)c2C ZCIHMQAPACOQHT-ZGMPDRQDSA-N 0.000 claims abstract description 18
- 235000019198 oils Nutrition 0.000 claims abstract description 17
- 150000008442 polyphenolic compounds Chemical class 0.000 claims abstract description 17
- 235000013824 polyphenols Nutrition 0.000 claims abstract description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 7
- 239000002245 particle Substances 0.000 claims abstract description 6
- 238000005292 vacuum distillation Methods 0.000 claims abstract description 5
- 230000003064 anti-oxidating effect Effects 0.000 claims abstract 2
- -1 polyoxy Polymers 0.000 claims description 8
- 150000001875 compounds Chemical class 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 6
- 239000003995 emulsifying agent Substances 0.000 claims description 5
- 239000007788 liquid Substances 0.000 claims description 5
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 claims description 4
- 239000012153 distilled water Substances 0.000 claims description 4
- 239000004519 grease Substances 0.000 claims description 4
- 238000003756 stirring Methods 0.000 claims description 4
- DKSRNSSBMXOZAJ-UHFFFAOYSA-N dodecanoic acid;ethene Chemical compound C=C.CCCCCCCCCCCC(O)=O DKSRNSSBMXOZAJ-UHFFFAOYSA-N 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 230000010355 oscillation Effects 0.000 claims 1
- 238000005086 pumping Methods 0.000 claims 1
- 230000003078 antioxidant effect Effects 0.000 abstract description 18
- 238000000926 separation method Methods 0.000 abstract description 9
- 239000003963 antioxidant agent Substances 0.000 abstract description 7
- 230000000694 effects Effects 0.000 abstract description 4
- 239000002904 solvent Substances 0.000 abstract description 3
- 239000002131 composite material Substances 0.000 abstract description 2
- 239000000463 material Substances 0.000 abstract description 2
- 238000011084 recovery Methods 0.000 abstract description 2
- 244000269722 Thea sinensis Species 0.000 abstract 1
- 230000003915 cell function Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 235000016709 nutrition Nutrition 0.000 abstract 1
- 230000035764 nutrition Effects 0.000 abstract 1
- 241001122767 Theaceae Species 0.000 description 15
- 239000012530 fluid Substances 0.000 description 15
- 239000003921 oil Substances 0.000 description 14
- 238000000034 method Methods 0.000 description 13
- 210000004027 cell Anatomy 0.000 description 7
- 235000006708 antioxidants Nutrition 0.000 description 5
- 230000000975 bioactive effect Effects 0.000 description 5
- 230000004071 biological effect Effects 0.000 description 5
- 230000003647 oxidation Effects 0.000 description 4
- 238000007254 oxidation reaction Methods 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 239000004480 active ingredient Substances 0.000 description 3
- 239000013543 active substance Substances 0.000 description 3
- 239000002199 base oil Substances 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 238000004821 distillation Methods 0.000 description 3
- 238000000874 microwave-assisted extraction Methods 0.000 description 3
- 235000015097 nutrients Nutrition 0.000 description 3
- 201000004624 Dermatitis Diseases 0.000 description 2
- LGJMUZUPVCAVPU-UHFFFAOYSA-N beta-Sitostanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 LGJMUZUPVCAVPU-UHFFFAOYSA-N 0.000 description 2
- 235000019197 fats Nutrition 0.000 description 2
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 2
- VKOBVWXKNCXXDE-UHFFFAOYSA-N icosanoic acid Chemical compound CCCCCCCCCCCCCCCCCCCC(O)=O VKOBVWXKNCXXDE-UHFFFAOYSA-N 0.000 description 2
- 238000007654 immersion Methods 0.000 description 2
- IYRMWMYZSQPJKC-UHFFFAOYSA-N kaempferol Chemical compound C1=CC(O)=CC=C1C1=C(O)C(=O)C2=C(O)C=C(O)C=C2O1 IYRMWMYZSQPJKC-UHFFFAOYSA-N 0.000 description 2
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 description 2
- 239000003642 reactive oxygen metabolite Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- OILXMJHPFNGGTO-UHFFFAOYSA-N (22E)-(24xi)-24-methylcholesta-5,22-dien-3beta-ol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(C)C(C)C)C1(C)CC2 OILXMJHPFNGGTO-UHFFFAOYSA-N 0.000 description 1
- NTWLPZMPTFQYQI-UHFFFAOYSA-N (3alpha)-olean-12-ene-3,23-diol Natural products C1CC(O)C(C)(CO)C2CCC3(C)C4(C)CCC5(C)CCC(C)(C)CC5C4=CCC3C21C NTWLPZMPTFQYQI-UHFFFAOYSA-N 0.000 description 1
- OYHQOLUKZRVURQ-NTGFUMLPSA-N (9Z,12Z)-9,10,12,13-tetratritiooctadeca-9,12-dienoic acid Chemical compound C(CCCCCCC\C(=C(/C\C(=C(/CCCCC)\[3H])\[3H])\[3H])\[3H])(=O)O OYHQOLUKZRVURQ-NTGFUMLPSA-N 0.000 description 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- MIJYXULNPSFWEK-GTOFXWBISA-N 3beta-hydroxyolean-12-en-28-oic acid Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CCC(C)(C)C[C@H]5C4=CC[C@@H]3[C@]21C MIJYXULNPSFWEK-GTOFXWBISA-N 0.000 description 1
- OQMZNAMGEHIHNN-UHFFFAOYSA-N 7-Dehydrostigmasterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CC(CC)C(C)C)CCC33)C)C3=CC=C21 OQMZNAMGEHIHNN-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- UBSCDKPKWHYZNX-UHFFFAOYSA-N Demethoxycapillarisin Natural products C1=CC(O)=CC=C1OC1=CC(=O)C2=C(O)C=C(O)C=C2O1 UBSCDKPKWHYZNX-UHFFFAOYSA-N 0.000 description 1
- JKLISIRFYWXLQG-UHFFFAOYSA-N Epioleonolsaeure Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4CCC3C21C JKLISIRFYWXLQG-UHFFFAOYSA-N 0.000 description 1
- GCGBHJLBFAPRDB-UHFFFAOYSA-N Hederagenin Natural products CC1(C)CCC2(CCC3(C)C4CCC5C(C)(CO)C(O)CCC5(C)C4CC=C3C2C1)C(=O)O GCGBHJLBFAPRDB-UHFFFAOYSA-N 0.000 description 1
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 1
- YBRJHZPWOMJYKQ-UHFFFAOYSA-N Oleanolic acid Natural products CC1(C)CC2C3=CCC4C5(C)CCC(O)C(C)(C)C5CCC4(C)C3(C)CCC2(C1)C(=O)O YBRJHZPWOMJYKQ-UHFFFAOYSA-N 0.000 description 1
- MIJYXULNPSFWEK-UHFFFAOYSA-N Oleanolinsaeure Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4=CCC3C21C MIJYXULNPSFWEK-UHFFFAOYSA-N 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 235000021314 Palmitic acid Nutrition 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- GCGBHJLBFAPRDB-KCVAUKQGSA-N Scutellaric acid Natural products CC1(C)CC[C@@]2(CC[C@@]3(C)[C@@H]4CC[C@H]5[C@@](C)(CO)[C@H](O)CC[C@]5(C)[C@H]4CC=C3[C@@H]2C1)C(=O)O GCGBHJLBFAPRDB-KCVAUKQGSA-N 0.000 description 1
- 240000003768 Solanum lycopersicum Species 0.000 description 1
- 235000021355 Stearic acid Nutrition 0.000 description 1
- LUKBXSAWLPMMSZ-OWOJBTEDSA-N Trans-resveratrol Chemical compound C1=CC(O)=CC=C1\C=C\C1=CC(O)=CC(O)=C1 LUKBXSAWLPMMSZ-OWOJBTEDSA-N 0.000 description 1
- HZYXFRGVBOPPNZ-UHFFFAOYSA-N UNPD88870 Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)=CCC(CC)C(C)C)C1(C)CC2 HZYXFRGVBOPPNZ-UHFFFAOYSA-N 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 150000001299 aldehydes Chemical class 0.000 description 1
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 description 1
- 235000020661 alpha-linolenic acid Nutrition 0.000 description 1
- XADJWCRESPGUTB-UHFFFAOYSA-N apigenin Natural products C1=CC(O)=CC=C1C1=CC(=O)C2=CC(O)=C(O)C=C2O1 XADJWCRESPGUTB-UHFFFAOYSA-N 0.000 description 1
- 235000008714 apigenin Nutrition 0.000 description 1
- KZNIFHPLKGYRTM-UHFFFAOYSA-N apigenin Chemical compound C1=CC(O)=CC=C1C1=CC(=O)C2=C(O)C=C(O)C=C2O1 KZNIFHPLKGYRTM-UHFFFAOYSA-N 0.000 description 1
- 229940117893 apigenin Drugs 0.000 description 1
- OGBUMNBNEWYMNJ-UHFFFAOYSA-N batilol Chemical class CCCCCCCCCCCCCCCCCCOCC(O)CO OGBUMNBNEWYMNJ-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229940076810 beta sitosterol Drugs 0.000 description 1
- NJKOMDUNNDKEAI-UHFFFAOYSA-N beta-sitosterol Natural products CCC(CCC(C)C1CCC2(C)C3CC=C4CC(O)CCC4C3CCC12C)C(C)C NJKOMDUNNDKEAI-UHFFFAOYSA-N 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 235000021466 carotenoid Nutrition 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 239000008160 cosmetics carrier oil Substances 0.000 description 1
- 230000006837 decompression Effects 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 125000004494 ethyl ester group Chemical group 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- PGOYMURMZNDHNS-MYPRUECHSA-N hederagenin Chemical compound C1C[C@H](O)[C@@](C)(CO)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CCC(C)(C)C[C@H]5C4=CC[C@@H]3[C@]21C PGOYMURMZNDHNS-MYPRUECHSA-N 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 235000008777 kaempferol Nutrition 0.000 description 1
- 229960004488 linolenic acid Drugs 0.000 description 1
- KQQKGWQCNNTQJW-UHFFFAOYSA-N linolenic acid Natural products CC=CCCC=CCC=CCCCCCCCC(O)=O KQQKGWQCNNTQJW-UHFFFAOYSA-N 0.000 description 1
- LRDGATPGVJTWLJ-UHFFFAOYSA-N luteolin Natural products OC1=CC(O)=CC(C=2OC3=CC(O)=CC(O)=C3C(=O)C=2)=C1 LRDGATPGVJTWLJ-UHFFFAOYSA-N 0.000 description 1
- 235000009498 luteolin Nutrition 0.000 description 1
- IQPNAANSBPBGFQ-UHFFFAOYSA-N luteolin Chemical compound C=1C(O)=CC(O)=C(C(C=2)=O)C=1OC=2C1=CC=C(O)C(O)=C1 IQPNAANSBPBGFQ-UHFFFAOYSA-N 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- UXOUKMQIEVGVLY-UHFFFAOYSA-N morin Natural products OC1=CC(O)=CC(C2=C(C(=O)C3=C(O)C=C(O)C=C3O2)O)=C1 UXOUKMQIEVGVLY-UHFFFAOYSA-N 0.000 description 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 229940100243 oleanolic acid Drugs 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 235000021313 oleic acid Nutrition 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 230000036542 oxidative stress Effects 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- HZLWUYJLOIAQFC-UHFFFAOYSA-N prosapogenin PS-A Natural products C12CC(C)(C)CCC2(C(O)=O)CCC(C2(CCC3C4(C)C)C)(C)C1=CCC2C3(C)CCC4OC1OCC(O)C(O)C1O HZLWUYJLOIAQFC-UHFFFAOYSA-N 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000001054 red pigment Substances 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 description 1
- 229950005143 sitosterol Drugs 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- 230000009759 skin aging Effects 0.000 description 1
- 210000004927 skin cell Anatomy 0.000 description 1
- 230000037380 skin damage Effects 0.000 description 1
- 230000036620 skin dryness Effects 0.000 description 1
- 230000036559 skin health Effects 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- HCXVJBMSMIARIN-PHZDYDNGSA-N stigmasterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)/C=C/[C@@H](CC)C(C)C)[C@@]1(C)CC2 HCXVJBMSMIARIN-PHZDYDNGSA-N 0.000 description 1
- 229940032091 stigmasterol Drugs 0.000 description 1
- BFDNMXAIBMJLBB-UHFFFAOYSA-N stigmasterol Natural products CCC(C=CC(C)C1CCCC2C3CC=C4CC(O)CCC4(C)C3CCC12C)C(C)C BFDNMXAIBMJLBB-UHFFFAOYSA-N 0.000 description 1
- 235000016831 stigmasterol Nutrition 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 235000018991 trans-resveratrol Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B1/00—Production of fats or fatty oils from raw materials
- C11B1/02—Pretreatment
- C11B1/04—Pretreatment of vegetable raw material
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B1/00—Production of fats or fatty oils from raw materials
- C11B1/10—Production of fats or fatty oils from raw materials by extracting
- C11B1/104—Production of fats or fatty oils from raw materials by extracting using super critical gases or vapours
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
一种基于牡丹籽的化妆品用油的生产方法，属于化妆品加工技术领域。本发明将牡丹籽通过干燥、粉碎至一定粒度；加入乙醇和乙酸乙酯微波辅助预处理后，以乙醇和乙酸乙酯为夹带剂进行超临界CO2萃取，压力为20～30ＭＰa、温度45～50℃条件下萃取；接着在分离罐中在压力３ＭＰa～６ＭＰa、温度25～30℃下分离。经减压蒸馏回收乙醇和乙酸乙酯后，萃取油通过增溶后加入肌肽、茶多酚和番茄红素复合抗氧化剂，得到抗氧化牡丹籽油。本发明提取速度快、提取率高，无溶剂残留，获得的高品质油水分活度低，具有抗氧化及营养细胞功能，保水性能和贮藏性俱佳，可用作于高档化妆品基质原料。
Description
技术领域
本发明属于化妆品加工技术领域，涉及化妆品用油的生产方法。
背景技术
基本原理：牡丹籽约含油25-30%，牡丹籽油还有丰富的亚麻酸、亚油酸、油酸、花生烯酸、软脂酸和硬脂酸等，同时，还含有齐墩果酸、常春藤皂苷元、山奈酚、木犀草素、柯伊利素、芹菜素、反式葡根素、反式白藜芦醇、顺式葡根素、豆甾醇、β－谷甾醇、和β－胡萝卜苷等多种生物活性成分，用于化妆品能使柔软润滑、营养皮肤细胞的作用。番茄红素能促使细胞的生长和再生，美容袪皱，维持皮肤健康，延缓衰老等功效，可大大改善皮肤过敏症，消除因皮肤过敏而引起的皮肤干燥和瘙痒感，令人感觉轻松愉快。肌肽可清除在氧化应激过程中使细胞膜的脂肪酸过度氧化而形成的活性氧自由基（ROS）以及α-β不饱和醛。可以防止肌肤的衰老及肌肤增白的作用，肌肽可防止游离基产生，修复皮肤损伤，具有营养细胞的功能。
微波处理的原理是利用高频电磁波穿透萃取介质，到达被萃取物料的内部，微波能迅速转化为热能而使细胞内部的温度快速上升。当细胞内部的压力超过细胞的承受能力时，细胞就会破裂，有效成分即从胞内流出，并在较低的温度下溶解于萃取介质。
超临界CO2流体萃取分离的原理是利用超临界流体的溶解能力与其密度的关系，即利用压力和温度对超临界流体溶解能力的影响而进行萃取。在超临界状态下，将超临界流体与待分离的物质接触，使其有选择性地把极性大小、沸点高低和分子量大小不同的成分依次萃取出来。当然，对应各压力范围所得到的萃取物不可能是单一的，但可以控制条件得到最佳比例的混合成分，然后借助减压、升温的方法使超临界流体变成普通气体，被萃取物质则完全或基本析出，从而达到分离提纯的目的，所以超临界CO2流体萃取过程是由萃取和分离过程组合而成的。超临界CO2流体萃取的最大优势是无溶剂残留，天然活性物质得到很好的保留。在本发明中，乙醇和乙酸乙酯在超临界CO2流体萃取过程中起夹带剂的作用，可以提高萃取效率。而不同于一般的有机溶剂，根据GB 2760-96规定乙醇和乙酸乙酯为允许使用的食用香料，用于化妆品更没有毒副作用。萃取之后于45-60℃条件下，高真空进行减压蒸馏可回收乙醇和乙酸乙酯得到产品。在该工艺条件下提取的油脂具有生物活性的同时，其抗氧化活性低，容易氧化变质。肌肽、茶多酚和番茄红具有非常好的抗氧化性能，三者同时存在时还具有协同作用，使抗氧化活性大大提高。但是肌肽和茶多酚均不溶于油脂，番茄红素不溶于水，不能将三者直接加入油脂中，通过研究发现将肌肽和茶多酚溶于水后，加入HLB值5-6的单甘脂和HLB值12-15的非离子型聚氧乙烯单月桂酸酯的二元复合乳化剂可以促使番茄红素溶解，再加入油脂中形成油包水的微粒而均匀分散，效果很好，再用超声波震荡混匀得到具有抗氧化活性高生物活性的牡丹籽油，其含有丰富的营养物质，可用作化妆品的基质。
发明内容
本发明的目的是提供一种基于牡丹籽的化妆品用油的生产方法，用于生产化妆品的基质用油。通过微波辅助预处理后超临界CO2流体萃取牡丹籽油，添加肌肽、茶多酚和番茄红素提高抗氧化活性，得到功能化的抗氧化生物活性牡丹籽油。
该方法通过将牡丹籽干燥、粉碎至一定粒度后；加入乙醇和乙酸乙酯微波辅助预处理，之后在一定工艺条件下采用超临界CO2流体萃取植物油及有效成分，减压蒸馏回收乙醇和乙酸乙酯后，再采用一定方法添加茶多酚等提高抗氧化活性，得到具有抗氧化活性高生物活性的牡丹籽油。该方法的主要优点是在该工艺条件下超临界CO2流体萃取所得的牡丹籽油，生物活性物质含量高，损失小。加入肌肽、茶多酚和番茄红素后具有良好的抗氧化特性，用该方法生产的油脂可做化妆品的基质用油，含有大量生物活性及营养物质。
本发明是通过以下技术方案实现的。
本发明所述的一种基于牡丹籽的化妆品用油的生产方法，按如下步骤。
1）将牡丹籽通过干燥、粉碎至一定粒度。
2）乙醇和乙酸乙酯微波辅助预处理。
3）以乙醇和乙酸乙酯为夹带剂超临界CO2流体萃取。
4）减压蒸馏回收乙醇和乙酸乙酯。
5）加入肌肽、茶多酚和番茄红素提高抗氧化特性。
所述微波辅助预处理，指用微波提取反应系统在2450MHz处理5-10分钟。
所述超临界CO2流体萃取，指萃取罐中压力为20～30ＭＰa、温度45～50℃条件下萃取；分离罐中压力３ＭＰa～5ＭＰa、温度25～30℃下分离。
所述提高抗氧化性。指将肌肽和茶多酚溶于蒸馏水，加入HLB值5-6的单甘脂和HLB值12-15的非离子型聚氧乙烯单月桂酸酯的二元复合乳化剂，加入番茄红素加热30-40℃，使之完全溶解，将上述溶液缓慢滴加入第４）步萃取所得的牡丹籽油中并快速搅拌，分散成均匀的单相油状液体，用超声波震荡混匀；肌肽、茶多酚和番茄红素在油脂中总含量（质量比）不低于0.01%，得到功能化的抗氧化生物活性牡丹籽油。
其主要的原理步骤：1.将牡丹籽通过干燥、粉碎至一定粒度；2.乙醇和乙酸乙酯微波辅助预处理；3. 在一定工艺条件以乙醇和乙酸乙酯为夹带剂进行超临界CO2流体萃取。4.减压蒸馏回收乙醇和乙酸乙酯；5.加入肌肽、茶多酚和番茄红素提高抗氧化特性。用该方法的主要优点是在该工艺条件下超临界CO2流体萃取所得的牡丹籽油，生物活性物质含量高，损失小，加入肌肽、茶多酚和番茄红素后具有高抗氧化特性，提高储藏期，防止变质。该方法生产的油脂可做化妆品的基质用油，含有大量生物活性及营养物质。
本发明的有益效果：本发明提供一种客观的具有抗氧化活性的高生物活性化妆品用油的生产方法。该方法可以客观有效地提取高活性牡丹籽油，相比于溶剂萃取具有无溶剂残留的特性，通过添加复合抗氧化剂具有高抗氧化活性，可以用于化妆品基质用油的生产。
具体实施方式
本发明将通过以下实施例作进一步说明。
实施例1。
1）将牡丹籽通过干燥、粉碎至30目过筛。
2）加入乙醇和乙酸乙酯浸没，用微波提取反应系统（如法国PROLABO公司的SOS-1100系列产品）在2450MHz处理5-10分钟。
3）然后将上述混合物用超临界CO2设备（如广州美晨300L型）萃取3h，萃取条件：萃取罐中压力为25ＭＰa、温度45～50℃条件下萃取；分离罐中压力３ＭＰa、温度25℃下分离。
４）第３)步得到的油脂化合物，在40-50℃抽真空，减压蒸馏回收乙醇和乙酸乙酯。
5)将提高抗氧化性。将肌肽和茶多酚溶于蒸馏水，加入HLB值5-6的单甘脂和HLB值12-15的非离子型聚氧乙烯单月桂酸酯的二元复合乳化剂，加入番茄红素加热30-40℃，使之完全溶解，将上述溶液缓慢滴加入第３）步萃取所得的牡丹籽油中并快速搅拌，分散成均匀的单相油状液体，用超声波震荡混匀；肌肽、茶多酚和番茄红素在油脂中总含量（质量比）不低于0.01%，得到功能化的抗氧化生物活性牡丹籽油。
实施例2。
1）将牡丹籽通过干燥、粉碎至30目过筛。
2）加入乙醇和乙酸乙酯浸没，用微波提取反应系统（如法国PROLABO公司的SOS－1100系列产品）在2450MHz处理8分钟。
3）然后将上述混合物用超临界CO2设备（如广州美晨300L型）萃取2h，萃取条件：萃取罐中压力为25ＭＰa、温度45℃条件下萃取；分离罐中压力３ＭＰa、温度25℃下分离。
４）第３)步得到的油脂化合物，在50℃抽真空，减压蒸馏回收乙醇和乙酸乙酯。
5)将提高抗氧化性。将肌肽和茶多酚溶于蒸馏水，加入HLB值5-6的单甘脂和HLB值12-15的非离子型聚氧乙烯单月桂酸酯的二元复合乳化剂，加入番茄红素加热40℃，使之完全溶解，将上述溶液缓慢滴加入第4）步萃取所得的牡丹籽油中并快速搅拌，分散成均匀的单相油状液体，用超声波震荡混匀；肌肽、茶多酚和番茄红素在油脂中总含量（质量比）不低于0.3%，得到功能化的抗氧化生物活性牡丹籽油。
Claims (1)
1.一种基于牡丹籽的化妆品用油的生产方法，其特征是按如下步骤：
1）将牡丹籽通过干燥、粉碎至一定粒度；
2）在粉碎的牡丹籽中加入适量的乙醇和乙酸乙酯，微波预处理3-10分钟，使细胞破壁；
3）将步骤（2）所得的混合物以乙醇和乙酸乙酯为夹带剂，用超临界CO2在萃取罐中以压力20～30ＭＰa、温度45～50℃条件下萃取；接着在分离罐中以压力３ＭＰa～4ＭＰa、温度25～30℃下分离；
4）将步骤（３）得到油脂，在45-60℃，抽高真空进行减压蒸馏回收除去乙醇和乙酸乙酯，得到牡丹籽油；
5）将肌肽和茶多酚溶于蒸馏水，加入HLB值5-6的单甘脂和HLB值12-15的非离子型聚氧乙烯单月桂酸酯的二元复合乳化剂，加入番茄红素加热30-40℃，使之完全溶解，将上述溶液缓慢滴加入步骤（４）萃取所得的牡丹籽油中并快速搅拌，分散成均匀的单相油状液体，用超声波震荡混匀；肌肽、茶多酚和番茄红素在油脂中总含量的质量比不低于0.01%，得到功能化的抗氧化生物活性牡丹籽油。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710250986.1A CN107216942A (zh) | 2017-04-18 | 2017-04-18 | 一种基于牡丹籽的化妆品用油的生产方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710250986.1A CN107216942A (zh) | 2017-04-18 | 2017-04-18 | 一种基于牡丹籽的化妆品用油的生产方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107216942A true CN107216942A (zh) | 2017-09-29 |
Family
ID=59927861
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710250986.1A Withdrawn CN107216942A (zh) | 2017-04-18 | 2017-04-18 | 一种基于牡丹籽的化妆品用油的生产方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107216942A (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108685992A (zh) * | 2018-07-31 | 2018-10-23 | 上品（洛阳）牡丹产业有限公司 | 一种具有细胞修复功能的牡丹花籽油原液及其制备方法 |
-
2017
- 2017-04-18 CN CN201710250986.1A patent/CN107216942A/zh not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108685992A (zh) * | 2018-07-31 | 2018-10-23 | 上品（洛阳）牡丹产业有限公司 | 一种具有细胞修复功能的牡丹花籽油原液及其制备方法 |
| CN108685992B (zh) * | 2018-07-31 | 2021-03-02 | 上品（洛阳）牡丹产业有限公司 | 一种具有细胞修复功能的牡丹花籽油原液及其制备方法 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103045356B (zh) | 亚麻籽油的生产方法 | |
| CN101243871A (zh) | 一种大蒜油的提取方法 | |
| CN107011988B (zh) | 一种椰子油提取工艺及其椰子油 | |
| CN102936532A (zh) | 一种椰子油的提取工艺 | |
| CN108424816A (zh) | 一种百里香精油的提取工艺 | |
| CN102433216A (zh) | 一种提取亚麻油的方法 | |
| CN107177407A (zh) | 一种基于美藤果的化妆品用油的生产方法 | |
| CN103409230B (zh) | 一种正丁烷-乙醇-水双相溶剂低温提取植物油脂的方法 | |
| CN107164075A (zh) | 一种基于腊梅的化妆品用油的生产方法 | |
| Charpe et al. | Effect of ethanol concentration in ultrasound assisted extraction of glycyrrhizic acid from licorice root | |
| CN104263504B (zh) | 一种光皮梾木果油的提取方法 | |
| CN106987308A (zh) | 一种基于杏仁的化妆品用油的生产方法 | |
| CN107034006A (zh) | 一种基于蚕蛹的化妆品用油的生产方法 | |
| CN107201268A (zh) | 一种基于辣木籽的化妆品用油的生产方法 | |
| JP2017057298A (ja) | ポリイソプレンの製造方法 | |
| CN107216942A (zh) | 一种基于牡丹籽的化妆品用油的生产方法 | |
| CN103540400B (zh) | 一种利用亚临界液-液萃取技术分离水脂混溶成分的方法 | |
| CN107083271A (zh) | 一种基于山茶花籽的化妆品用油的生产方法 | |
| CN101524099A (zh) | 超临界co2萃取技术制备原生态椰子油的方法 | |
| CN107022408A (zh) | 一种基于番木瓜籽的化妆品用油的生产方法 | |
| CN107164078A (zh) | 一种基于余甘子核仁的化妆品用油的生产方法 | |
| CN107189849A (zh) | 一种基于红花籽的化妆品用油的生产方法 | |
| CN107034008A (zh) | 一种基于红麻籽的化妆品用油的生产方法 | |
| CN114836258A (zh) | 利用酿酒后的葡萄籽提取葡萄籽油的方法 | |
| CN107011983A (zh) | 一种基于紫苏的化妆品用油的生产方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20170929 |