CN107157579A - A kind of pedicle screw is implanted into paths planning method - Google Patents
A kind of pedicle screw is implanted into paths planning method Download PDFInfo
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Abstract
本发明涉及医学领域,尤其涉及一种脊柱椎弓根螺钉植入路径规划方法。该方法包括如下步骤:S1、术前规划:对术前患者CT影像数据进进行预处理,根据脊柱椎弓根的解剖特点在脊柱椎弓根螺钉植入3D规划系统中进行手术路径规划确定最佳植入路径;S2、在脊柱椎弓根螺钉植入3D规划系统中调整脊柱3D位姿,截取左右椎弓根螺钉模拟轴位图;S3、术中标准轴位图获取:采用脊柱椎弓根螺钉植入2D导航系统,通过调整C型臂,获取术中脊柱的X‑Ray轴位图;S4、术中椎弓根螺钉植入路径确认:在脊柱椎弓根螺钉植入2D导航系统中,将3D规划系统导出的椎弓根螺钉模拟轴位图与术中X‑Ray轴位图进行配准,确定脊柱椎弓根螺钉植入点。该方法可以快速、精准的确定椎弓根螺钉植入点的位置,减少人为因素影响。
The invention relates to the medical field, in particular to a path planning method for spinal pedicle screw implantation. The method includes the following steps: S1. Preoperative planning: Preprocessing the CT image data of the preoperative patient, performing surgical path planning in the 3D planning system for spinal pedicle screw implantation according to the anatomical characteristics of the spinal pedicle screw implantation to determine the optimal Optimum implantation path; S2. Adjust the 3D posture of the spine in the 3D planning system for spinal pedicle screw implantation, and intercept the simulated axial images of the left and right pedicle screws; S3. Acquisition of the standard axial images during the operation: using the spinal arch The root screw is implanted into the 2D navigation system, and the X-Ray axial map of the spine is obtained during the operation by adjusting the C-arm; S4. Confirmation of the pedicle screw implantation path during the operation: the 2D navigation system is implanted in the spinal pedicle screw In this procedure, the pedicle screw simulation axial image derived from the 3D planning system was registered with the intraoperative X-Ray axial image to determine the implantation point of the spinal pedicle screw. This method can quickly and accurately determine the position of the implantation point of the pedicle screw, reducing the influence of human factors.
Description
技术领域technical field
本发明涉及医学领域,尤其涉及一种脊柱椎弓根螺钉植入路径规划方法。The invention relates to the medical field, in particular to a path planning method for spinal pedicle screw implantation.
背景技术Background technique
椎弓根螺钉技术由于其在脊柱三柱固定生物力学方面的优越性,使得它在脊柱外科手术中被广泛应用。但常规开放椎弓根固定融合手术需要对椎旁肌进行广泛的剥离和长时间的牵拉,这样往往导致椎旁肌肉的去神经和萎缩,引起脊柱融合病的发生。近年来,随着现代医学科学技术的进步,人们在力求椎弓根螺钉植入的安全和准确的同时,又探索运用微创的手段经皮植入椎弓根螺钉,从而有效的减少人为损伤。由于经皮椎弓根螺钉技术的出现避免了传统脊柱后路内固定植入手术的大切口、肌肉剥离多,术后康复慢等的缺点,目前它已经逐渐成为微创脊柱外科的基本技术手段之一。Pedicle screw technology is widely used in spinal surgery due to its biomechanical superiority in three-column fixation. However, conventional open pedicle fixation and fusion surgery requires extensive stripping and long-term stretching of the paraspinal muscles, which often leads to denervation and atrophy of the paraspinal muscles, resulting in the occurrence of spinal fusion disease. In recent years, with the advancement of modern medical science and technology, while striving for the safety and accuracy of pedicle screw implantation, people have also explored the use of minimally invasive means to implant pedicle screws percutaneously, thereby effectively reducing artificial injuries . Since the emergence of percutaneous pedicle screw technology avoids the disadvantages of large incision, multiple muscle stripping, and slow postoperative recovery in traditional posterior spinal internal fixation surgery, it has gradually become the basic technical means of minimally invasive spinal surgery. one.
由于椎弓根狭窄,螺钉一旦穿出椎弓根的侧壁,手术即失败。经椎弓根内固定手术成败的关键是螺钉能否准确地经椎弓根到达椎体。因此从后路正确地找到椎弓根标志,进以确定螺钉的入点及进针方向极为重要。实际手术中医生多凭借经验,参照X光图像的脊柱解剖点进行徒手植入,目前手术失败率高达30%。Due to the stenosis of the pedicle, once the screw passes through the side wall of the pedicle, the operation will fail. The key to the success of transpedicular internal fixation is whether the screw can accurately reach the vertebral body through the pedicle. Therefore, it is very important to correctly find the pedicle landmark from the posterior approach to determine the entry point of the screw and the direction of the needle. In the actual operation, doctors rely on experience and refer to the anatomical points of the spine in X-ray images to perform freehand implantation. At present, the failure rate of the operation is as high as 30%.
最理想的手术路径,是采用椎弓根标准轴定位原理,就是让椎弓根的轴线与C型臂X光机的发射轴线尽可能重叠,保证手术植入路径与椎弓根轴线平行,选择椎弓根椭圆形猫眼的中心位置,就可以得到椎弓根植入的最佳路径。专利CN104224306A提供了一种利用三维建模寻找椎弓根螺钉最佳入点的方法,可以辅助医生在术前完成手术路径规划。但是实际手术中,椎弓根螺钉植入点的确定一般都是凭借经验进行人为的选择,无法保证实际手术路径与规划路径一致。The most ideal surgical path is to use the principle of pedicle standard axis positioning, which is to make the axis of the pedicle overlap with the emission axis of the C-arm X-ray machine as much as possible, so as to ensure that the surgical implantation path is parallel to the axis of the pedicle. The best path for pedicle implantation can be obtained by the central position of the oval cat's eye of the pedicle. Patent CN104224306A provides a method of using three-dimensional modeling to find the best entry point of pedicle screws, which can assist doctors to complete surgical path planning before surgery. However, in actual surgery, the determination of the pedicle screw implantation point is generally based on experience and artificial selection, which cannot guarantee that the actual surgical path is consistent with the planned path.
由于主观因素的影响,实际手术中用户选择的位置都不一样。而选择位置的准确性严重影响到椎弓根螺钉的植入效果,选择不当,甚至会造成螺钉穿出椎弓根侧壁,造成手术失败。如何科学、合理、精准的找到螺钉植入点的位置,在椎弓根螺钉植入手术过程中将显得尤为重要。Due to the influence of subjective factors, the positions selected by users in actual operations are different. The accuracy of the selected position seriously affects the implantation effect of the pedicle screw, and improper selection may even cause the screw to pass through the side wall of the pedicle, resulting in failure of the operation. How to scientifically, rationally and accurately find the position of the screw implantation point will be particularly important in the process of pedicle screw implantation.
发明内容Contents of the invention
(一)要解决的技术问题(1) Technical problems to be solved
本发明的目的在于提供一种脊柱椎弓根螺钉植入路径规划方法,该方法能够快速、精准的找到脊柱椎弓根标准轴位图中的螺钉植入点。The purpose of the present invention is to provide a spinal pedicle screw implantation path planning method, which can quickly and accurately find the screw implantation point in the standard axial map of the spinal pedicle.
(二)技术方案(2) Technical solution
为达成上述目的,本发明提供一种脊柱椎弓根螺钉植入路径规划方法,如图1所示,包括如下步骤:S1、术前规划:对术前患者CT影像数据进分割处理与三维重建,根据脊柱椎弓根的解剖特点在脊柱椎弓根螺钉植入3D规划系统中进行手术路径规划确定最佳植入路径;S2、在脊柱椎弓根螺钉植入3D规划系统,调整脊柱3D位姿,截取左右椎弓根螺钉模拟轴位图;S3、术中标准轴位图获取:采用脊柱椎弓根螺钉植入2D导航系统,通过调整C型臂,获取术中脊柱的X-Ray轴位图;S4、术中椎弓根螺钉植入路径确认:在脊柱椎弓根螺钉植入2D导航系统中,将3D规划系统导出的椎弓根螺钉模拟轴位图与术中X-Ray轴位图进行配准,确定脊柱椎弓根螺钉植入点。In order to achieve the above object, the present invention provides a method for planning the path of spinal pedicle screw implantation, as shown in Figure 1, including the following steps: S1, preoperative planning: performing segmentation processing and three-dimensional reconstruction of preoperative patient CT image data , according to the anatomical characteristics of the spinal pedicle screw implantation 3D planning system in the spinal pedicle screw implantation 3D planning system to determine the optimal implantation path; S3, obtain the standard axial image during operation: use the spinal pedicle screw to implant the 2D navigation system, and obtain the X-Ray axis of the spine during operation by adjusting the C-arm Bitmap; S4. Intraoperative pedicle screw implantation path confirmation: In the spinal pedicle screw implantation 2D navigation system, the pedicle screw simulation axis map exported by the 3D planning system and the intraoperative X-Ray axis The bitmap was registered to determine the implantation point of the spinal pedicle screw.
根据本发明,脊柱椎弓根轴位图是指在投影图像上,椎弓根轴前后表面的边缘投影所形成的两个圆环重合时的投影图像。According to the present invention, the axial pedicle diagram of the spine refers to the projected image when two rings formed by the edge projections of the front and rear surfaces of the pedicle shaft overlap on the projected image.
根据本发明,在步骤S1中,对术前患者CT影像数据进行预处理,包括:对术前CT图像进行分割与三维重建,导入到脊柱椎弓根螺钉植入3D规划系统中的CT数据包括DICOM数据和分割好的STL数据。According to the present invention, in step S1, preprocessing the preoperative CT image data of the patient includes: performing segmentation and three-dimensional reconstruction on the preoperative CT image, and the CT data imported into the 3D planning system for spinal pedicle screw implantation includes: DICOM data and segmented STL data.
根据本发明,在步骤S1中,所述的脊柱椎弓根的解剖特点:According to the present invention, in step S1, the anatomical characteristics of the described spinal pedicle:
1)包括,脊柱的左右关键点以及椎弓根螺钉植入的左右终点;1) Including the left and right key points of the spine and the left and right end points of pedicle screw implantation;
2)左右关键点和左右终点的选取是通过X、Y、Z(分别为红、绿、蓝,如图2所示)三平面相交点来确定的;2) The selection of the left and right key points and the left and right end points is determined by the intersection points of the three planes of X, Y, and Z (respectively red, green, and blue, as shown in Figure 2);
3)关键点位于椎弓根中心,红色线位于左弓根中心处(图4右下方横断面图)、蓝色线位于椎弓根中心处(右上方侧位图),蓝色线位于熊猫眼中心处(图4左下方正位图);3) The key point is located at the center of the pedicle, the red line is located at the center of the left pedicle (lower right cross-sectional view in Figure 4), the blue line is located at the center of the pedicle (upper right lateral view), and the blue line is located at the center of the panda At the center of the eye (orthographic view at the bottom left of Figure 4);
4)终点位于椎体的1/3,如图5所示右侧图。4) The end point is located at 1/3 of the vertebral body, as shown on the right side of Figure 5.
根据本发明,在步骤S2中,脊柱椎弓根螺钉植入3D规划系统能够根据规划好的左右椎弓根螺钉植入路径生成模拟的标准轴位图(如图9所示),并进行保存。According to the present invention, in step S2, the spinal pedicle screw implantation 3D planning system can generate a simulated standard axial map (as shown in Figure 9 ) according to the planned left and right pedicle screw implantation paths, and save it .
根据本发明,在步骤S3中,脊柱椎弓根螺钉植入2D导航系统能够根据拍摄到的X-ray图像和脊柱的特征数据,计算出C臂的调整量,使调整C臂后,能够得到标准的X-ray轴位图(如图10所示)。According to the present invention, in step S3, the spinal pedicle screw implantation 2D navigation system can calculate the adjustment amount of the C arm according to the captured X-ray image and the characteristic data of the spine, so that after the adjustment of the C arm, it can be obtained Standard X-ray axis map (as shown in Figure 10).
根据本发明,在步骤S4中,脊柱椎弓根螺钉植入2D导航系统能够导入X-ray图像和3D软件导出的模拟轴位图,导航系统能够对左右标准轴位图进行平移、旋转、缩放,实现轴位图与X-ray图叠加配准。According to the present invention, in step S4, the 2D navigation system for spinal pedicle screw implantation can import X-ray images and simulated axial maps derived from 3D software, and the navigation system can translate, rotate, and zoom the left and right standard axial maps , to realize the overlay registration of the axis map and the X-ray map.
根据本发明,在步骤S4中,轴位图与X-ray图叠加配准之后,选择轴位图中钉子的中心位置作为螺钉植入点(如图12所示)。According to the present invention, in step S4, after the axial image and the X-ray image are superimposed and registered, the center position of the nail in the axial image is selected as the screw implantation point (as shown in FIG. 12 ).
(三)有益效果(3) Beneficial effects
本发明的脊柱椎弓根螺钉植入路径规划方法,能够科学、合理的规划出椎弓根螺钉植入路径,降低椎弓根螺钉植入时,路径点的定位严重依赖医生经验、主观性强,容易出现偏差等问题,提高手术的安全性,进而,减少对患者的辐射次数,降低了危害,缩短了手术时间,降低了医疗成本。The path planning method for spinal pedicle screw implantation of the present invention can scientifically and reasonably plan the path of pedicle screw implantation, and reduce the location of path points when pedicle screw implantation is heavily dependent on the doctor's experience and subjectivity , prone to problems such as deviation, improve the safety of the operation, and then reduce the number of radiation to the patient, reduce the harm, shorten the operation time, and reduce the medical cost.
附图说明Description of drawings
图1是脊柱椎弓根螺钉植入路径规划方法的实施的流程图Figure 1 is a flowchart of the implementation of the path planning method for spinal pedicle screw implantation
图2是脊柱椎弓根螺钉植入3D规划系统软件示图Figure 2 is a schematic diagram of the 3D planning system software for spinal pedicle screw implantation
图3是规划脊柱段选择Figure 3 is the planning spine segment selection
图4是规划左关键点Figure 4 is the planning left key point
图5是规划左终点Figure 5 is the planning left end point
图6是左侧椎弓根螺钉规划路径效果图Figure 6 is the effect diagram of the planned path of the left pedicle screw
图7是不同角度下左侧椎弓根螺钉规划路径3D示图Figure 7 is a 3D diagram of the planned path of the left pedicle screw at different angles
图8是右侧椎弓根螺钉规划路径效果图Figure 8 is the effect diagram of the planned path of the right pedicle screw
图9是3D软件中获取的模拟轴位图(A为右侧、B为左侧)Figure 9 is the simulated axial map obtained in the 3D software (A is the right side, B is the left side)
图10是术中拍摄的X-ray轴位图Figure 10 is the X-ray axial view taken during the operation
图11是模拟轴位图与X-ray轴位图配准结果Figure 11 is the registration result of the simulated axis map and the X-ray axis map
图12是术中螺钉位置植入点Figure 12 is the screw position and implantation point during the operation
具体实施方式detailed description
下面将结合附图对本发明作进一步的详细说明。The present invention will be further described in detail below in conjunction with the accompanying drawings.
参照图1所示,本发明的具体实施方式共包括S1~S4步骤。具体实施方式如下:Referring to FIG. 1 , a specific embodiment of the present invention includes steps S1 to S4. The specific implementation is as follows:
步骤S1术前规划:Step S1 preoperative planning:
步骤S1.1:采用MIMICS或其他医学图像处理软件,对患者的术前CT数据进行分割处理,得到患者脊柱骨表面,并进行三维重建导出STL模型。Step S1.1: Use MIMICS or other medical image processing software to segment and process the patient's preoperative CT data to obtain the patient's spinal bone surface, and conduct 3D reconstruction to export the STL model.
步骤S1.2:在脊柱椎弓根螺钉植入3D规划系统软件中导入患者的DICOM数据和分割好的STL数据。Step S1.2: Import the patient's DICOM data and segmented STL data into the 3D planning system software for spinal pedicle screw implantation.
如图2所示,左上方为3D示图,右上方为侧位图(矢状面),左下方为正位图(冠状面)、右下方为(横断面);通过调节X、Y、Z平面(分别显示为红、绿、蓝)的位置和转角调节脊柱在三视图中的位置、转角、和大小。As shown in Figure 2, the upper left is a 3D diagram, the upper right is a lateral view (sagittal plane), the lower left is a front view (coronal plane), and the lower right is a (transverse section); by adjusting X, Y, The position and rotation of the Z plane (shown in red, green, and blue, respectively) adjusts the position, rotation, and size of the spine in the three views.
步骤S1.3:如图3所示,调整脊柱三视图,校正脊柱图像,调节规划线位使其位于当前脊柱关节上。Step S1.3: As shown in Figure 3, adjust the three views of the spine, correct the image of the spine, and adjust the planning line so that it is located on the current spine joint.
步骤S1.4:规划左侧椎弓根螺钉植入路径。Step S1.4: Planning the implantation path of the left pedicle screw.
步骤S1.4.1:规划左关键点,调节红色线位于左弓根中心处(如图4右下方横断面图)、蓝色线位于椎弓根中心处(如图4右上方侧位图),蓝色线位于熊猫眼中心处(如图4左下方正位图),三平面的交点即为左关键点;Step S1.4.1: Plan the left key point, adjust the red line to be located at the center of the left pedicle (as shown in the lower right cross-sectional view of Figure 4), and the blue line to be located at the center of the pedicle (as shown in the upper right lateral view of Figure 4), The blue line is located at the center of the panda's eye (as shown in the lower left orthographic image of Figure 4), and the intersection of the three planes is the left key point;
步骤S1.4.2:规划左终点,调节绿色规划线至椎体的1/3处(如图5所示右侧图),三平面的交点即为左终点。Step S1.4.2: Plan the left end point, adjust the green planning line to 1/3 of the vertebral body (as shown in the right diagram in Figure 5), and the intersection of the three planes is the left end point.
如图6所示,完成左关键点以及左终点规划后,规划路径效果。As shown in Figure 6, after completing the planning of the left key point and the left end point, plan the path effect.
如图7所示,不同角度下3D示图中的手术路径规划效果。As shown in Fig. 7, the surgical path planning effect in the 3D diagram under different angles.
步骤S1.5:参照步骤S1.4.1以及步骤S1.4.2规划右侧椎弓根螺钉植入路径,规划效果如图8所示。Step S1.5: Refer to step S1.4.1 and step S1.4.2 to plan the implantation path of the right pedicle screw, and the planning effect is shown in Figure 8.
步骤S2:调节脊柱的位姿,分别沿规划的脊柱椎弓根左右侧路径进行投影,得到左右椎弓根螺钉标准轴位图(如图9所示),并保存。Step S2: adjust the posture of the spine, and project along the planned left and right paths of the spinal pedicle respectively to obtain a standard axial view of the left and right pedicle screws (as shown in FIG. 9 ), and save it.
步骤S3:获取术中X-Ray轴位图:根据术中脊柱的特征点,通过2D导航系统计算C臂调整参数,调整C臂位姿,直到获取到脊柱的右侧标准轴位图。在X-Ray图像上,椎弓根轴前后表面的边缘投影所形成的两个圆环重合(如图10所示)。Step S3: Obtain the intraoperative X-Ray axial map: According to the feature points of the spine during the operation, the C-arm adjustment parameters are calculated through the 2D navigation system, and the C-arm pose is adjusted until the right standard axial map of the spine is obtained. On the X-Ray image, the two rings formed by the edge projections of the front and rear surfaces of the pedicle shaft coincide (as shown in Figure 10).
步骤S4:确定椎弓根螺钉植入点:Step S4: Determine the pedicle screw insertion point:
步骤S4.1:将图6A所示的模拟标准右轴位图入到脊柱椎弓根螺钉植入2D导航系统中;Step S4.1: importing the simulated standard right axial view shown in Fig. 6A into the 2D navigation system for spinal pedicle screw implantation;
步骤S4.2:通过对模拟标准右轴位图平移、旋转、缩放,与X-ray标准右轴位图进行叠加配准,使得脊柱轮廓重合(如图11所示);Step S4.2: By translating, rotating, and scaling the simulated standard right-axis bitmap, superimposing and registering with the X-ray standard right-axis bitmap, so that the contours of the spine coincide (as shown in Figure 11);
步骤S4.3:选取模拟标准右轴位图中螺钉的位置中心,作为脊柱右侧的螺钉植入点(如图12所示);Step S4.3: Select the position center of the screw in the simulated standard right axial view as the screw implantation point on the right side of the spine (as shown in Figure 12);
步骤S4.4:按照图12所示的脊柱右侧的螺钉植入点,根据导航系统指示植入脊柱右侧椎弓根螺钉。Step S4.4: According to the screw implantation point on the right side of the spine as shown in Figure 12, insert the pedicle screw on the right side of the spine according to the guidance of the navigation system.
步骤S4.5:重复步骤S3、S4.1-S4.4,植入脊柱左侧椎弓根螺钉。Step S4.5: Repeat steps S3, S4.1-S4.4, implant the left pedicle screw of the spine.
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