CN106727266A - A kind of anti-aging isolation suncream and preparation method thereof - Google Patents
A kind of anti-aging isolation suncream and preparation method thereof Download PDFInfo
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- CN106727266A CN106727266A CN201611209653.6A CN201611209653A CN106727266A CN 106727266 A CN106727266 A CN 106727266A CN 201611209653 A CN201611209653 A CN 201611209653A CN 106727266 A CN106727266 A CN 106727266A
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- suncream
- aging
- extract solution
- spirulina
- isolation
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- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 description 1
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
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- A61K8/736—Chitin; Chitosan; Derivatives thereof
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/988—Honey; Royal jelly, Propolis
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Abstract
The invention belongs to cosmetic technical field, and in particular to a kind of anti-aging isolation suncream and preparation method thereof.The anti-aging isolation suncream that the present invention is provided includes following components and its mass percent：Spirulina 12~20%, extract solution from aloe 12~18%, pawpaw extract solution 12~18%, propolis 4~6%, beta glucan 2~3%, vitamin E 2~3%, squalene 1~2%, xanthans 1~2%, jojoba oil 1~2%, L malic acid 1~2%, chitosan oligosaccharide 1~2%, carnosine 1~2% and water 20~50%.It is of the invention it is a technical advantage that：Formula reasonable benefit/risk, it is gently non-stimulated to skin rich in multiple nutritional components, sun-proof and anti-aging the ability of the overall isolation of skin can be improved.
Description
Technical field
The invention belongs to cosmetic technical field, and in particular to a kind of anti-aging isolation suncream and preparation method thereof.
Background technology
Among modern city, the injury to skin such as Exposure to Sunlight, haze, radiation, color make-up is ubiquitous, triggers various skins
Problem, such as skin are intense darkness without light, skin elasticity reduction, color spot, wrinkle, acne etc..Skin due to non-genetic factor cause it is quick
Sense phenomenon is more and more, and people also just arise at the historic moment to the demand of protective cosmetics, after facial treatment milk, toner, foundation cream
After liquid and suncream, sun screen has turned into one of indispensable cosmetics of modern female.The chemically sun-proof and physics of suncream point
Property sun-proof two major class, chemically suncream reach sun-proof result through ultraviolet light, it is physical it is sun-proof then to reflect, scatters ultraviolet
To prevent the injury of UVA and UVB.
Chinese patent application CN105147531A discloses a kind of suncream and preparation method thereof, by methoxycinnamate
Acid, benzophenone, p-aminobenzoic acid, titanium dioxide, salicylic acid, silica flour, emulsifying agent, Radix Codonopsis, root of Mebranous Milkvetch, Yunnan is tasteless,
The root bark of Chinese wolf-berry, glutinous rehmannia, trillium, holly leaf, Hai Fen, Triglochin martimum, the root of straight ladybell, the stem of noble dendrobium.The present invention contains physical sun-prevention component titanium dioxide
Titanium, physical sun-prevention component is exactly directly to be stopped using the particle in sunscreen productses, reflect or scatter ultraviolet, and titanium dioxide can
To intercept UVB and UVA, but the UVA of long wavelength part cannot be protected completely.
Chinese patent CN104161680A discloses a kind of isolation intensified day moisture, and formula material is myristyl alcohol, lanolin
Derivative, ultra-violet absorber, Glucamate SSE-20 ethoxylates, Glucate SS fatty acid esters, deionized water and
Stearmide stearyl single ethanol ammonium salt.PH value of the present invention is approached with human body skin, to no skin irritation, is substantially felt after use
To comfortable, softness, without greasy feeling, with obvious isolation sun-proof result.Wherein ultra-violet absorber is sun-proof group chemically
Point, the ultraviolet part in sunlight and fluorescence light source can be absorbed, and itself does not change.But it is physical and chemically
Suncream, after sunlight, can all produce free radical, damage Skin Cell, trigger cytometaplasia, cause cutaneum carcinoma.
The content of the invention
To solve the problems, such as prior art, the present invention provides a kind of anti-aging isolation suncream and preparation method thereof.
Anti-aging of the present invention isolates suncream, including following components and its mass percent：
Spirulina 12~20%, extract solution from aloe 12~18%, pawpaw extract solution 12~18%, propolis 4~6%, β-Portugal
Glycan 2~3%, vitamin E 2~3%, squalene 1~2%, xanthans 1~2%, jojoba oil 1~2%, L MALIC ACID 1
~2%, chitosan oligosaccharide 1~2%, carnosine 1~2% and water 20~50%.
Preferably, described anti-aging isolation suncream, is made up of following components and mass percent：
Spirulina 16%, extract solution from aloe 15%, pawpaw extract solution 15%, propolis 5%, beta glucan 2.5%, vitamin
E 2.5%, squalene 1.5%, xanthans 1.5%, jojoba oil 1.5%, L MALIC ACID 1.5%, chitosan oligosaccharide 1.5%, carnosine
1.5% and water 35%.
In addition, present invention also offers the preparation method that a kind of anti-aging isolates suncream, comprising the following steps：
S1, first spirulina is put into water and is soaked 5-10 hour, then boiled, it is right to be cooled to room temperature after seething with excitement 3-5 hours
After filter, obtain spirulina extract；
Extract solution from aloe, pawpaw extract solution, propolis, beta glucan, dimension are added in S2, the spirulina extract obtained to S1
Raw element E, squalene, xanthans, jojoba oil, L MALIC ACID, chitosan oligosaccharide and carnosine are well mixed, and are cooled to room temperature, sterilized
Bottling afterwards is obtained final product.
Preferably, spirulina is put into water in step S1 and is soaked 7.5 hours.
Further preferably, seethed with excitement 4 hours after spirulina is soaked in step S1.
Spirulina CAS：724424-92-4；Extract solution from aloe CAS：85507-69-3；Pawpaw extract solution CAS：
84012-30-6；Propolis CAS：8012-89-3；Beta glucan CAS：9051-97-2；Vitamin E CAS：1406-18-
4；Squalene CAS：7683-64-9；Xanthans CAS：11138-66-2；Jojoba oil CAS：61789-91-1；L- apples
Tartaric acid CAS：97-67-6；Chitosan oligosaccharide CAS：148411-57-8；Carnosine CAS：305-84-0.
Spirulina is made up of 18 kinds of amino acid, comprising amino acid that is needed by human and cannot synthesizing, its content it is not only high but also
Comprehensively, also containing abundant vitamin, polysaccharide, unrighted acid and mineral matter element, body immunity defense function is promoted
And the beta carotene of anti-aging, the various vitamins that human body is needed most, including vitamin B1、B2、B3、B6、B12, C, E etc., it is rich
The several mineral materials such as calcic, iron, zinc, selenium, potassium, magnesium, iodine.The superoxide dismutase (SOD) of high content can antiradiation injury
Peroxide anion free radical can be reasonably resistant to again, with anti-aging effects.Because spirulina contains more potassium, calcium, sodium
Deng alkali ion, therefore the acidic materials of skin can be neutralized, enhanced metabolism, while also having antioxidation, can caught
Free radical is obtained, skin peroxidization is prevented, so as to delay wrinkle to occur and skin senescence.
The application of aloe beauty is almost widely known, the derivative of natural anthraquinone glycoside or anthracene in aloe, can absorb ultraviolet
Line, prevents that skin is red, foxiness is produced, and aloe polysaccharide and vitamin have good nutrition to the skin of human body, moistens, brightens in addition
Effect, aloe is offseted except acne have good effect.
Containing abundant papain in pawpaw extract solution, vitamin C, vitamin B and calcium, phosphorus and mineral matter, also rich in β recklessly
Radish element, protein, calcium salt, protease, lemon enzyme etc., papain play the role of the aging cutin layer for decomposing removal skin surface,
Or a kind of natural antioxidant, is effective against the oxidation of systemic cell, and destruction makes human body accelerate the oxygen radical of aging.
Propolis is the resin of setting the positions such as bud, bark collection of the honeybee from plant, then is mixed with glands such as lingual gland, the wax glands of honeybee
Body secretion, a kind of colloid substance processed through honeybee various functions such as have anti-inflammatory, antipruritic, anti-oxidant, enhancing immune.
Beta glucan can adjust blood sugar, enhance immunity, the effect of antitumor, anti-ageing aspect of waiting for a long time.
Vitamin E can capture the free radical caused by ultraviolet as natural antioxidant, protect Skin Cell from
Oxidative damage, so as to help skin to resist light aging.
Squalene is a kind of lipid unsaponifiable matter, is found from the liver oil of shark, with the internal super oxygen of raising
Various functions such as compound mutase (SOD) activity, enhancing immunity of organisms, anti-aging, antifatigue, being that one kind is avirulent has
The marine biomaterial of preventing disease theraping effect.
Xanthans, also known as yellow glue, xanthan gum, is fermented through Xanthomonas campestris by carbohydrate, the extracellular microbial polysaccharide of generation,
Due to its macromolecular special construction and colloid property, and there are various functions, emulsifying agent, stabilizer, gelling thickener can be made
Deng.
Jojoba oil contains mineral matter, vitamin, protein, collagen, vegetable wax etc., with high stability and well
Permeability, and the grease of molecules align and people is closely similar, is the base oil that stability is high, ductility is particularly good.
L MALIC ACID contains natural moisturizing composition, can easily dissolve be bonded in the dead cell for drying flakey it
Between " sicker ", such that it is able to remove wrinkle of skin, skin is become tender white, bright and clean and flexible, therefore in cosmetics
Enjoy favor.
Chitosan oligosaccharide can eliminate human body oxygen radical, activation body cell, anti-aging, suppress skin surface harmful bacteria and grow
Raw, performance of keeping humidity is excellent.
The dipeptides that carnosine is made up of Beta-alanine-L-Histidine, carnosine is proved to be potent antioxidant, Neng Gouyou
Effect quenching activity oxygen radical, protects cell membrane, carnosine to suppress saccharification reaction as good anti-saccharifying agent, effectively be quenched
Light base free radical, moreover it is possible to prevent the crosslinking of the macromoleculars such as collagen, reduces the generation of wrinkle, constituted as skin
Point, natural, safety can help impaired skin tissue to repair, and improve the immunocompetence of skin, and there is heavy metal ion complexing to make
With, can not only play a part of dispelling toxicity, detoxicating, for also be can help in cosmetics series maintain formula stability.
Compatibility of the present invention is reasonable, science, and each component is cooperated, synergy, and anti-aging and sun-proof isolation are played jointly
Effect.
Compared with prior art, it is of the invention it is a technical advantage that：Formula reasonable benefit/risk, rich in multiple nutritional components to skin
Skin is gently non-stimulated, can improve sun-proof and anti-aging the ability of the overall isolation of skin.
Specific embodiment
The present invention is described in further details below by specific embodiment, these embodiments are only used for the mesh of illustration
, it is in no way intended to limit protection scope of the present invention.
Embodiment 1-3, comparative example 1-2
The specific embodiment 1-3 and comparative example of anti-aging isolation suncream provided by the present invention are listed in table 1 respectively
The component and mass percent of 1-2.
The embodiment of table 1 and comparative example isolate the component and mass percent of suncream
Comparative example 1 is with the difference of embodiment 2：Without beta glucan, increase the content of propolis.
Comparative example 2 is with the difference of embodiment 2：Without chitosan oligosaccharide, increase the content of carnosine.
The anti-aging of embodiment 1 isolates the preparation method of suncream：
S1, first spirulina is put into water and is soaked 5 hours, then boiled, boiling is cooled to room temperature and then mistake after 3 hours
Filter, obtains spirulina extract；
Extract solution from aloe, pawpaw extract solution, propolis, beta glucan, dimension are added in S2, the spirulina extract obtained to S1
Raw element E, squalene, xanthans, jojoba oil, L MALIC ACID, chitosan oligosaccharide and carnosine are well mixed, and are cooled to room temperature, sterilized
Bottling afterwards is obtained final product.
The anti-aging of embodiment 2 isolates the preparation method of suncream：
S1, first spirulina is put into water and is soaked 7.5 hours, then boiled, boiling is cooled to room temperature and then mistake after 4 hours
Filter, obtains spirulina extract；
Extract solution from aloe, pawpaw extract solution, propolis, beta glucan, dimension are added in S2, the spirulina extract obtained to S1
Raw element E, squalene, xanthans, jojoba oil, L MALIC ACID, chitosan oligosaccharide and carnosine are well mixed, and are cooled to room temperature, sterilized
Bottling afterwards is obtained final product.
The anti-aging of embodiment 3 isolates the preparation method of suncream：
S1, first spirulina is put into water and is soaked 10 hours, then boiled, boiling is cooled to room temperature and then mistake after 5 hours
Filter, obtains spirulina extract；
Extract solution from aloe, pawpaw extract solution, propolis, beta glucan, dimension are added in S2, the spirulina extract obtained to S1
Raw element E, squalene, xanthans, jojoba oil, L MALIC ACID, chitosan oligosaccharide and carnosine are well mixed, and are cooled to room temperature, sterilized
Bottling afterwards is obtained final product.
The preparation method of comparative example 1-2 isolation suncreams is similar to Example 2.
Properties of product evaluation test
Test example 1：Product index is evaluated
With reference to People's Republic of China (PRC) light industry professional standard QB/T 1857-2013《Moisturizing cream》Relevant criterion, it is right
The anti-aging isolation suncream that the embodiment of the present invention is prepared is tested, and the results are shown in Table 2.
The embodiment anti-aging of table 2 isolation suncream sense organ, physics and chemistry, sanitary index test result
The sense organ and physicochemical property of the anti-aging isolation suncream that as can be seen from Table 2 prepared by the embodiment of the present invention are good.
With reference to the Ministry of Public Health《Cosmetics health specification》The related request and measure of " human body skin patch " in (version in 2007)
The anti-aging isolation suncream that method is prepared to the embodiment of the present invention is tested, test result indicate that embodiment is prepared into
The isolation suncream for arriving is without skin adverse reaction.
Test example 2：SPF is determined
With reference to the Ministry of Public Health《Cosmetics health specification》" sun care preparations SPF (spf value) is determined in (version in 2007)
The related request and assay method of method " are carried out.Given the test agent is that the isolation that the embodiment of the present invention and comparative example are prepared is prevented
Shine frost.Choose 90 trial volunteers to be tested, be randomly divided into 5 groups, every group of 18 people the results are shown in Table 3.
The embodiment of table 3 and the sun-proof the performance test results of comparative example sun screen
| Group | Embodiment 1 | Embodiment 2 | Embodiment 3 | Comparative example 1 | Comparative example 2 |
| Spf value | 15 | 16 | 15 | 12 | 13 |
From the test result of table 3 can be seen that the embodiment of the present invention 1-3 preparation sun screen spf value than comparative example 1-2 every
Spf value from frost is high, and illustrates the anti-aging sun screen of present invention offer to ultraviolet than convenient human body skin 15 or so
Line has good obstruct and absorbent properties, and sun-proof result is good.
Test example 3：Sun screen anti-aging effects of the present invention are evaluated
1. given the test agent：The sun screen that embodiment of the present invention 1-3 and comparative example 1-2 are prepared.
2. experimental animal：Take the kunming mice 60 of health, 9-11 week old, body weight 35-45g, male and female half and half.By body weight with
Machine is divided into blank control group, embodiment 1-3 groups and comparative example 1-2 groups, every group 10.
3. test method：Each group mouse is lost hair or feathers with 0.8% vulcanized sodium back, exposes the test section of 4cm × 4cm.Smear
Skin first is cleaned with warm water before sun screen, daily sooner or later each once corresponding sun screen, wherein blank control group smears physiology salt
Water, continuous to smear 30 days, period shaves off the new mouse hair for growing in time.After last smears 12h, clip mouse test section skin group
Knit, prepare skin histology homogenate, with kit measurement superoxide dismutase (SOD) vigor and MDA (MDA) content.Examination
Test and the results are shown in Table 4.
Influence of the sun screen of the present invention of table 4 to MDA, SOD content in skin histology homogenate
| Group | Blank control group | Embodiment 1 | Embodiment 2 | Embodiment 3 | Comparative example 1 | Comparative example 2 |
| MDA(nmol/mgprot) | 3.36 | 2.46 | 2.23 | 2.65 | 3.24 | 3.42 |
| SOD(U/mgprot) | 126.52 | 147.32 | 159.25 | 153.23 | 136.28 | 128.84 |
As shown in Table 4, embodiment of the present invention 1-3 anti-agings isolation suncream is remarkably improved the vigor of SOD in skin, drop
The content of low MDA, illustrating the anti-aging isolation suncream of present invention offer has good anti-aging effects, wherein, embodiment 2
Effect it is the most notable, be preferred embodiment.Compared with embodiment 1-3, the anti-aging effect of comparative example 1-2 group sun screens
Fruit is poor compared with embodiment 1-3, illustrates that anti-aging visage block cream each component of the present invention is mutually cooperateed with.
The above is only the preferred embodiment of the present invention, it is noted that it is right that above-mentioned preferred embodiment is not construed as
Limitation of the invention, protection scope of the present invention should be defined by claim limited range.For the art
For those of ordinary skill, without departing from the spirit and scope of the present invention, some improvements and modifications can also be made, these change
Enter and retouch and also should be regarded as protection scope of the present invention.
Claims (5)
1. a kind of anti-aging isolates suncream, it is characterised in that including following components and its mass percent：
Spirulina 12~20%, extract solution from aloe 12~18%, pawpaw extract solution 12~18%, propolis 4~6%, beta glucan 2
~3%, vitamin E 2~3%, squalene 1~2%, xanthans 1~2%, jojoba oil 1~2%, L MALIC ACID 1~2%,
Chitosan oligosaccharide 1~2%, carnosine 1~2% and water 20~50%.
2. anti-aging according to claim 1 isolates suncream, it is characterised in that by following components and mass percent group
Into：Spirulina 16%, extract solution from aloe 15%, pawpaw extract solution 15%, propolis 5%, beta glucan 2.5%, vitamin E
2.5%th, squalene 1.5%, xanthans 1.5%, jojoba oil 1.5%, L MALIC ACID 1.5%, chitosan oligosaccharide 1.5%, carnosine
1.5% and water 35%.
3. anti-aging according to claim 1 and 2 isolates the preparation method of suncream, it is characterised in that including following step
Suddenly：
S1, first spirulina is put into water and is soaked 5-10 hour, then boiled, boiling is cooled to room temperature then mistake after 3-5 hours
Filter, obtains spirulina extract；
Extract solution from aloe, pawpaw extract solution, propolis, beta glucan, vitamin are added in S2, the spirulina extract obtained to S1
E, squalene, xanthans, jojoba oil, L MALIC ACID, chitosan oligosaccharide and carnosine are well mixed, and are cooled to room temperature, sterilized rear dress
Bottle is obtained final product.
4. anti-aging according to claim 3 isolates the preparation method of suncream, it is characterised in that by spiral in step S1
Algae is soaked 7.5 hours in being put into water.
5. anti-aging according to claim 3 isolates the preparation method of suncream, it is characterised in that by spiral in step S1
Seethed with excitement 4 hours after algae immersion.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107397703A (en) * | 2017-08-09 | 2017-11-28 | 北京军秀咨询有限公司 | A kind of cosmetics containing active peptide |
| CN109288775A (en) * | 2018-11-26 | 2019-02-01 | 纪翠苗 | A kind of alkalinity formula of sun screen |
| CN113925797A (en) * | 2021-10-27 | 2022-01-14 | 南京理工大学 | Application of β-1,3/α-1,3-glucan in the preparation of anti-ultraviolet sunscreen skin care products |
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| CN104207947A (en) * | 2014-08-18 | 2014-12-17 | 贵州捷欣合金技术开发有限公司 | Preparation method for film-forming liquid |
| CN105616212A (en) * | 2014-10-28 | 2016-06-01 | 赖婷婷 | Sunscreen cream |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104207947A (en) * | 2014-08-18 | 2014-12-17 | 贵州捷欣合金技术开发有限公司 | Preparation method for film-forming liquid |
| CN105616212A (en) * | 2014-10-28 | 2016-06-01 | 赖婷婷 | Sunscreen cream |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107397703A (en) * | 2017-08-09 | 2017-11-28 | 北京军秀咨询有限公司 | A kind of cosmetics containing active peptide |
| CN109288775A (en) * | 2018-11-26 | 2019-02-01 | 纪翠苗 | A kind of alkalinity formula of sun screen |
| CN113925797A (en) * | 2021-10-27 | 2022-01-14 | 南京理工大学 | Application of β-1,3/α-1,3-glucan in the preparation of anti-ultraviolet sunscreen skin care products |
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