CN106619213A - 一种缓释型天然植物驱蚊液的制备方法 - Google Patents
一种缓释型天然植物驱蚊液的制备方法 Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/02—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants
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Abstract
本发明公开了一种缓释型天然植物驱蚊液的制备方法,其特征在于,该方法具有以下工艺步骤:以亚油酸和豆蔻酸作为缓蚀剂,豆蔻酸作为增香剂,薄荷脑和樟脑为抑菌剂。按如下组成体积百分浓度和顺序加入,野菊花油:18~22%,香叶醇:22~26%,50%松油:12~18%,冬青油:12~18%,香茅油:8~12%,亚油酸:14~20%,搅拌混匀,在加入豆蔻酸乙醇溶液,薄荷脑和樟脑乙醇溶液,混合均匀后,得到黄色透明液体为缓释型天然植物驱蚊液。该驱蚊液散发自然清香气味,并具有抑菌、缓释作用,对人体无副作用,使用方便,持续时间在10到12小时,驱蚊效果平均在90%以上。
Description
技术领域
本发明涉及一种驱蚊制剂,特别涉及一种缓释型天然植物驱蚊液的制备方法及其在化妆品中的应用,属于化妆品技术领域。
背景技术
植物精油的主要成分为单萜、倍半萜、脂肪族化合物和芳香烃衍生物,具有很多种生物活性。目前,植物精油在抗菌、抗氧化、杀虫等方面已经形成一个新的领域。特别是针对卫生害虫的防治、天然除虫菊素、植物精油等植物源杀虫活性物质具有对人畜安全、延缓害虫抗药性、不污染居住环境等优点,在卫生杀虫领域具有巨大的开发潜力和应用价值。已经有研究表明植物精油可以通过熏蒸或触杀的方式杀死或弱化蚊蝇。一般认为熏蒸剂的作用机理是熏蒸剂的蒸汽通过害虫的表皮或气门进入呼吸系统,从而渗透到血液使害虫中毒死亡。
蚊虫吸食人血、传播疾病,严重危害人类健康。长期以来,人们使用多种方法控制蚊虫,各类化学杀虫剂对蚊虫的防治效果较好且持续时间较长,在某些地区的蚊媒病控制中的防治中起到重要作用。但是有机合成杀虫剂在高效杀虫的同时也遗留了许多问题。实践证明,随着化学杀虫剂大量长期的使用,蚊虫的抗药性越来越强,而且扩散迅速、污染环境影响生态平衡。因此,寻找对环境安全、对人体安全、易于降解、具有选择性驱蚊制剂备受关注。
驱蚊技术在我国化妆品领域是一种广泛应用的技术,传统的具有驱蚊效果的化妆品中主要是添加了化学合成的驱避剂,如避蚊胺(DEET)、驱蚊油(DMP)或香茅醛等,涂抹在皮肤上,形成保护膜、使蚊虫不敢靠近。然而,这种添加化学成分的驱避剂可能会造成皮肤过敏,具有一定的毒性,污染环境等。
近年来也有将植物提取物作为人体用蚊虫驱避剂的研究报道,如:野菊花、香叶油、金银花油、青蒿油、荆芥油、山苍油、松香油、冬青油、柠檬草油、柠檬桉油、香茅油、薰衣草油、丁香油等,但是这些以植物挥发油为主要成分的蚊虫驱避剂作用的时间很短,一般在1~2小时。而且单一植物精油驱避蚊虫效果不过理想,筛选几种植物精油进行复合驱蚊具有协同作用。许春晖等,对复方植物精油驱蚊效果进行了研究(许春晖等,复方植物精油驱蚊效果的研究,中华卫生杀虫药械,2014,第20卷,第3期);中国专利申请号为:201310267797.7的专利中公开了一种驱蚊止痒花露水及其制备方法;中国专利申请号为:201510747775.X的专利中公开了一种具有驱蚊效果的草本植物精油组合物;中国专利申请号为:201410379082.5的专利中公开了一种驱蚊香薰精油;中国专利申请号为:201610342621.7的专利中公开了一种纯天然精油驱蚊液及其制备方法;中国专利申请号为: 201210098867.6的专利中公开了一种可直接作用的驱蚊用天然植物精油组合物。
有不同种类的植物精油所含的活性物质不同,单一植物精油的驱蚊效果不理想,而且持续的时间短,本申请通过对植物精油的复配添加缓蚀剂等手段,获得一种缓释型天然植物驱蚊液,使其具有较高的驱蚊率、持续时间在10到12小时。
发明内容
本发明的目的之一是提供一种缓释型天然植物驱蚊液的制备方法,在于解决现有驱蚊剂存在的保留时间短,添加化学杀虫剂,驱蚊效果差等问题。提供一种原料来源广泛,成本低廉,驱蚊效果显著、安全无毒、同具有缓释缓释型天然植物驱蚊液。
本发明的目的通过以下技术方案实现。
一种缓释型天然植物驱蚊液的制备方法,其特征在于,该方法具有以下工艺步骤:
(1)A液配制:将豆蔻酸置于反应器中,加入乙醇,搅拌溶解,配成质量体积百分浓度为5~10%乙醇溶液,配成为A液,备用;
(2)B液配制:将薄荷脑和樟脑溶解在无水乙醇中,配成质量体积百分浓度,含薄荷脑:2~6%,樟脑:1~3%的乙醇溶液,室温放置24小时,得到B液,备用;
(3)C液配制:在反应器中,按如下组成体积百分浓度和顺序加入,野菊花油:18~22%,香叶醇:22~26%,50%松油:12~18%,冬青油:12~18%,香茅油:8~12%,亚油酸:14~20%,各组分之和为百分之百,搅拌混匀,得到C液;
(4)一种缓释型天然植物驱蚊液的制备:在反应器中,按A液:B液:C液的体积比为1:1:1比例进行混合,混合均匀后,得到黄色透明液体为一种缓释型天然植物驱蚊液,放置过夜,分装入容器中。
在步骤(2)所述的薄荷脑和樟脑的质量比在2:1为最优。
在步骤(2)所述的薄荷脑和樟脑均为植物提取物。
在步骤(3)所述的野菊花油、香叶醇、50%松油、冬青油、香茅油均为植物提取物。
在步骤(3)所述的50%松油其50%为质量体积百分浓度。
使用方法:缓释型天然植物驱蚊液可直接涂抹或喷洒在人体皮肤上。
本发明与现有技术比较,具有如下优点及有益效果:
(1)本发明获得的一种缓释型天然植物驱蚊液是采用天然植物精油为主要成分,不含有化学杀虫剂,绿色环保,安全无毒,具有良好的驱蚊功效,驱蚊效果平均在90%以上;
(2)本发明获得的一种缓释型天然植物驱蚊液使用时可直接涂抹或喷洒在人体皮肤上,天然精油组合物散发出自然清香味,并具有抑菌、止痒、润肤等作用,对人体无副作用,使用方便;
(3)本发明获得的一种缓释型天然植物驱蚊液由于添加了亚油酸是不饱和脂肪酸和豆蔻酸为饱和脂肪酸,不饱和脂肪算和饱和脂肪酸对植物精油具有缓释作用,使其驱蚊保留时间长,持续时间在10到12小时。豆蔻酸对植物精油具有增香作用,增加其驱蚊效果。
具体实施方式
实施例1
(1)A液配制:将8g豆蔻酸置于反应器中,加入100mL乙醇,搅拌溶解,配成为A液,备用;
(2)B液配制:将4g薄荷脑和2g樟脑溶解于100mL无水乙醇中,室温放置24小时,得到B液,备用;
(3)C液配制:在反应器中,分别加入,野菊花油:20mL,香叶醇:24mL,50%松油:15mL,冬青油:15mL,香茅油:10mL,亚油酸:16mL,搅拌混匀,得到C液;
(4)一种缓释型天然植物驱蚊液的制备:在反应器中,按A液:B液:C液的体积比为1:1:1比例进行混合,混合均匀后,得到黄色透明液体为一种缓释型天然植物驱蚊液,放置过夜,分装入容器中。
实施例2
(1)A液配制:将5g豆蔻酸置于反应器中,加入100mL乙醇,搅拌溶解,配成为A液,备用;
(2)B液配制:将6g薄荷脑和3g樟脑溶解于100mL无水乙醇中,室温放置24小时,得到B液,备用;
(3)C液配制:在反应器中,分别加入,野菊花油:18mL,香叶醇:26mL,50%松油:12mL,冬青油:18mL,香茅油:8mL,亚油酸:18mL,搅拌混匀,得到C液;
(4)一种缓释型天然植物驱蚊液的制备:在反应器中,按A液:B液:C液的体积比为1:1:1比例进行混合,混合均匀后,得到黄色透明液体为一种缓释型天然植物驱蚊液,放置过夜,分装入容器中。
实施例3
(1)A液配制:将10g豆蔻酸置于反应器中,加入100mL乙醇,搅拌溶解,配成为A液,备用;
(2)B液配制:将2g薄荷脑和1g樟脑溶解于100mL无水乙醇中,室温放置24小时,得到B液,备用;
(3)C液配制:在反应器中,分别加入,野菊花油:22mL,香叶醇:22mL,50%松油:18mL,冬青油:12mL,香茅油:12mL,亚油酸:14mL,搅拌混匀,得到C液;
(4)一种缓释型天然植物驱蚊液的制备:在反应器中,按A液:B液:C液的体积比为1:1:1比例进行混合,混合均匀后,得到黄色透明液体为一种缓释型天然植物驱蚊液,放置过夜,分装入容器中。
实施例4
(1)A液配制:将7g豆蔻酸置于反应器中,加入100mL乙醇,搅拌溶解,配成为A液,备用;
(2)B液配制:将5g薄荷脑和2g樟脑溶解于100mL无水乙醇中,室温放置24小时,得到B液,备用;
(3)C液配制:在反应器中,分别加入,野菊花油:21mL,香叶醇:23mL,50%松油:13mL,冬青油:14mL,香茅油:9mL,亚油酸:20mL,搅拌混匀,得到C液;
(4)一种缓释型天然植物驱蚊液的制备:在反应器中,按A液:B液:C液的体积比为1:1:1比例进行混合,混合均匀后,得到黄色透明液体为一种缓释型天然植物驱蚊液,放置过夜,分装入容器中。
实施例5
(1)A液配制:将9g豆蔻酸置于反应器中,加入100mL乙醇,搅拌溶解,配成为A液,备用;
(2)B液配制:将3g薄荷脑和3g樟脑溶解于100mL无水乙醇中,室温放置24小时,得到B液,备用;
(3)C液配制:在反应器中,分别加入,野菊花油:19mL,香叶醇:25mL,50%松油:14mL,冬青油:16mL,香茅油:11mL,亚油酸:15mL,搅拌混匀,得到C液;
(4)一种缓释型天然植物驱蚊液的制备:在反应器中,按A液:B液:C液的体积比为1:1:1比例进行混合,混合均匀后,得到黄色透明液体为一种缓释型天然植物驱蚊液,放置过夜,分装入容器中。
使用方法:一种一种缓释型天然植物驱蚊液使用时可直接涂抹或喷洒在人体皮肤上,天然精油组合物散发出自然清香味,并具有抑菌、消肿、长效、驱蚊等作用,对人体无副作用,使用方便;持续时间在10到12小时,驱蚊效果平均在90%以上。
Claims (6)
1.一种缓释型天然植物驱蚊液的制备方法,其特征在于,该方法具有以下工艺步骤:
(1)A液配制:将豆蔻酸置于反应器中,加入乙醇,搅拌溶解,配成质量体积百分浓度为5~10%乙醇溶液,配成为A液,备用;
(2)B液配制:将薄荷脑和樟脑溶解在无水乙醇中,配成质量百分浓度,含薄荷脑:2~6%,樟脑:1~3%的乙醇溶液,室温放置24小时,得到B液,备用;
(3)C液配制:在反应器中,按如下组成体积百分浓度和顺序加入,野菊花油:18~22%,香叶醇:22~26%,50%松油:12~18%,冬青油:12~18%,香茅油:8~12%,亚油酸:14~20%,各组分之和为百分之百,搅拌混匀,得到C液;
(4)缓释型天然植物驱蚊液的制备:在反应器中,按A液:B液:C液的体积比为1:1:1比例进行混合,混合均匀后,得到黄色透明液体为缓释型天然植物驱蚊液植物驱蚊液,放置过夜,分装入容器中。
2.根据权利要求1中所述的一种缓释型天然植物驱蚊液的制备方法,其特征在于,步骤(2)所述的薄荷脑和樟脑的质量比在2:1为最优。
3.根据权利要求1中所述的一种缓释型天然植物驱蚊液的制备方法,其特征在于,步骤(2)所述的薄荷脑和樟脑均为植物提取物。
4.根据权利要求1中所述的一种缓释型天然植物驱蚊液的制备方法,其特征在于,步骤(3)所述的野菊花油、香叶醇、50%松油、冬青油、香茅油均为植物提取物。
5.根据权利要求1中所述的一种缓释型天然植物驱蚊液的制备方法,其特征在于,步骤(3)所述的50%松油其50%为质量体积百分浓度。
6.根据权利要求1中所述的一种缓释型天然植物驱蚊液的制备方法所制备的缓释型天然植物驱蚊液。
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| CN115737509A (zh) * | 2023-01-10 | 2023-03-07 | 广州市雪蕾化妆品有限公司 | 一种植物基香水及其制备方法 |
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