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CN106618635B - Shear wave elastography method and device - Google Patents

Shear wave elastography method and device Download PDF

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CN106618635B
CN106618635B CN201710022522.5A CN201710022522A CN106618635B CN 106618635 B CN106618635 B CN 106618635B CN 201710022522 A CN201710022522 A CN 201710022522A CN 106618635 B CN106618635 B CN 106618635B
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CN106618635A (en
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罗建文
何琼
曹艳平
李国洋
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Tsinghua University
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    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5207Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of raw data to produce diagnostic data, e.g. for generating an image

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Abstract

本发明涉及一种剪切波弹性成像方法和装置,所述方法包括:获取待检测对象的采样数据,所述采样数据包括直角坐标系的超声图像数据;对所述直角坐标系的超声图像数据进行坐标转换,以将所述直角坐标系的超声图像数据转换为极坐标系的超声图像数据;通过预设处理方法对所述极坐标系的超声图像数据进行处理,以得到用于表征所述待检测对象的弹性模量的剪切波弹性成像;对所述剪切波弹性成像进行可视化处理,以用于显示所述待检测对象的弹性模量。基于坐标变换实现待检测对象的剪切波弹性成像,可以对待检测对象的长轴切面的剪切波和短轴切面的剪切波进行处理,以得到待检测对象的准确的弹性定量,提高对待检测对象的病理检测精度。

The present invention relates to a shear wave elastography method and device, the method comprising: acquiring sampling data of an object to be detected, the sampling data including ultrasonic image data in a Cartesian coordinate system; Coordinate conversion is performed to convert the ultrasonic image data of the rectangular coordinate system into ultrasonic image data of the polar coordinate system; the ultrasonic image data of the polar coordinate system is processed by a preset processing method to obtain the Shear wave elastography of the elastic modulus of the object to be detected; visualizing the shear wave elastography to display the elastic modulus of the object to be detected. The shear wave elastography of the object to be detected is realized based on coordinate transformation, and the shear wave of the long-axis section and the shear wave of the short-axis section of the object to be detected can be processed to obtain accurate elastic quantification of the object to be detected and improve the treatment The pathology detection accuracy of the detected object.

Description

剪切波弹性成像方法和装置Shear wave elastography method and device

技术领域technical field

本发明涉及超声波医疗技术领域,更具体地涉及一种剪切波弹性成像方法和装置。The present invention relates to the field of ultrasonic medical technology, and more particularly to a shear wave elastography method and device.

背景技术Background technique

超声成像由于具有实时、廉价、非侵入性和非电离辐射等优点而广泛地用于临床诊断。超声弹性成像,特别是基于声辐射力的剪切波成像,在组织弹性定性和定量的测量中发挥巨大的作用,例如,血管剪切波弹性成像对管壁的弹性定量起到至关重要的作用。然而由于一些组织本身的一些特性,导致相关技术中的剪切波弹性成像不能准确地对其进行弹性定性和定量,以血管为例来说,血管具有各向异性的特性,使得在血管剪切波弹性成像时,须要同时考虑血管的长轴切面的剪切波和短轴切面的剪切波,相关技术中的剪切波弹性成像仅仅能够对血管的长轴切面进行剪切波弹性成像,会造成血管的弹性定量不准确,降低血管的病理检测精度。Ultrasound imaging is widely used in clinical diagnosis due to its real-time, cheap, non-invasive and non-ionizing radiation advantages. Ultrasound elastography, especially shear wave imaging based on acoustic radiation force, plays a huge role in the qualitative and quantitative measurement of tissue elasticity, for example, vascular shear wave elastography is crucial for the quantification of vessel wall elasticity effect. However, due to some characteristics of some tissues, the shear wave elastography in the related art cannot accurately characterize and quantify the elasticity. Taking blood vessels as an example, blood vessels have anisotropic properties, so that when the blood vessels are sheared During wave elastography, it is necessary to consider both the shear wave of the long-axis section and the shear wave of the short-axis section of the blood vessel. The shear wave elastography in the related art can only perform shear wave elastography on the long-axis section of the blood vessel. It will cause inaccurate quantification of blood vessel elasticity and reduce the accuracy of pathological detection of blood vessels.

因此,需要提供一种剪切波弹性成像方法和装置,以至少部分地解决上述问题。Therefore, it is necessary to provide a shear wave elastography method and device to at least partly solve the above problems.

发明内容Contents of the invention

考虑到上述问题而提出了本发明一种剪切波弹性成像方法和装置,可以针对待检测对象,例如身体组织、血管等得到较准确的弹性定量,提高待检测对象的病理检测精度。In view of the above problems, a shear wave elastography method and device of the present invention is proposed, which can obtain more accurate elastic quantification for the object to be detected, such as body tissue, blood vessel, etc., and improve the pathological detection accuracy of the object to be detected.

根据本发明一方面,提供了一种剪切波弹性成像方法,所述方法包括:According to one aspect of the present invention, a shear wave elastography method is provided, the method comprising:

获取待检测对象的采样数据,所述采样数据包括直角坐标系的超声图像数据;对所述直角坐标系的超声图像数据进行坐标转换,以将所述直角坐标系的超声图像数据转换为极坐标系的超声图像数据;通过预设处理方法对所述极坐标系的超声图像数据进行处理,以得到用于表征所述待检测对象的弹性模量的剪切波弹性成像;对所述剪切波弹性成像进行可视化处理,以用于显示所述待检测对象的弹性模量。Acquiring sampling data of the object to be detected, the sampling data including ultrasonic image data in a rectangular coordinate system; performing coordinate conversion on the ultrasonic image data in the rectangular coordinate system to convert the ultrasonic image data in the rectangular coordinate system into polar coordinates Ultrasonic image data of the polar coordinate system; the ultrasonic image data of the polar coordinate system is processed by a preset processing method to obtain shear wave elastography used to characterize the elastic modulus of the object to be detected; the shear wave elastography Wave elastography performs visualization processing to display the elastic modulus of the object to be detected.

可选地,所述对所述直角坐标系的超声图像数据进行坐标转换包括:对所述直角坐标系的超声图像数据进行空间插值,以得到极坐标系的超声图像数据。Optionally, performing coordinate transformation on the ultrasonic image data in the rectangular coordinate system includes: performing spatial interpolation on the ultrasonic image data in the rectangular coordinate system to obtain ultrasonic image data in the polar coordinate system.

可选地,所述对所述直角坐标系的超声图像数据进行空间插值包括:确定所述待检测对象的几何中心;以及以所述几何中心为极坐标原点,根据预设采样率分别对极坐标系的角度方向和半径方向进行数据采样,以获得采样数据点;用所述直角坐标系的超声图像数据对所述采用数据点进行空间插值,以得到极坐标系的超声图像数据。Optionally, the spatial interpolation of the ultrasonic image data in the Cartesian coordinate system includes: determining the geometric center of the object to be detected; Perform data sampling in the angular direction and radial direction of the coordinate system to obtain sampling data points; use the ultrasonic image data in the rectangular coordinate system to perform spatial interpolation on the adopted data points to obtain ultrasonic image data in the polar coordinate system.

可选地,所述通过预设处理方法对所述极坐标系的超声图像数据进行处理包括:通过第一处理方法处理所述极坐标系的超声图像数据,以得到所述极坐标系的超声图像数据的任一数据点的位移和沿所述待检测对象的感兴趣方向传播的剪切波;以及,基于所述任一数据点的位移,通过第二处理方法对沿所述待检测对象环向传播的剪切波进行处理,以得到剪切波频散曲线。Optionally, the processing the ultrasonic image data of the polar coordinate system by a preset processing method includes: processing the ultrasonic image data of the polar coordinate system by a first processing method to obtain the ultrasonic image data of the polar coordinate system The displacement of any data point of the image data and the shear wave propagating along the direction of interest of the object to be detected; and, based on the displacement of any data point, a second processing method is used to The circumferentially propagating shear wave is processed to obtain the shear wave dispersion curve.

可选地,所述通过预设处理方法对所述极坐标系的超声图像数据进行处理还包括:基于所述任一数据点的位移和沿所述待检测对象环向传播的剪切波得到剪切波的传输速度。Optionally, the processing of the ultrasonic image data in the polar coordinate system by using a preset processing method further includes: obtaining a The velocity of the shear wave.

可选地,所述通过第一处理方法处理所述极坐标系的超声图像数据包括:对所述极坐标系的超声图像数据进行斑点追踪,以得到任一数据点的在所述极坐标系中的径向位移和环向位移;以及基于所述径向位移和环向位移建立位移时间曲线;对所述位移时间曲线进行二维傅里叶变换,以得到傅里叶变换结果,其中,所述傅里叶变换结果的不同角度范围表示剪切波的不同方向的运动信息;对感兴趣的角度进行加窗处理,后经过逆傅里叶变换,以得到沿所述待检测对象的感兴趣方向传播的剪切波。Optionally, the processing the ultrasonic image data in the polar coordinate system by the first processing method includes: performing speckle tracking on the ultrasonic image data in the polar coordinate system to obtain any data point in the polar coordinate system Radial displacement and circumferential displacement in; And establish displacement time curve based on described radial displacement and circumferential displacement; Carry out two-dimensional Fourier transform to described displacement time curve, to obtain Fourier transform result, wherein, The different angle ranges of the Fourier transform results represent motion information in different directions of the shear wave; windowing is performed on the angle of interest, and then undergoes inverse Fourier transform to obtain the sensory information along the object to be detected. Shear waves propagating in the direction of interest.

可选地,所述对所述极坐标系的超声图像数据进行斑点追踪包括:对所述极坐标系的超声图像数据中的任一数据点进行加窗处理,得到对应该数据点的数据窗;当前后连续两帧的超声图像数据中所述数据窗的相关性最大时,确定该数据点的在所述极坐标系中的径向位移和环向位移。Optionally, performing speckle tracking on the ultrasonic image data in the polar coordinate system includes: performing windowing processing on any data point in the ultrasonic image data in the polar coordinate system to obtain a data window corresponding to the data point ; When the correlation of the data window in the two consecutive frames of ultrasonic image data before and after is the largest, determine the radial displacement and the circumferential displacement of the data point in the polar coordinate system.

可选地,所述基于所述任一数据点的位移,以及通过第二处理方法对沿所述待检测对象环向传播的剪切波进行处理包括:基于所述任一数据点的位移,得到所述剪切波波前在不同时间到达位置得到的位移时间曲线;对所述位移时间曲线进行二维傅里叶变换,以得到傅里叶变换结果,所述傅里叶变换结果中包括频率值和任一频率值对应的所有波数值;针对感兴趣的角度,基于所述感兴趣的角度中每个所述频率值对应的最大波数值建立剪切波频散曲线。Optionally, the said displacement based on any one of the data points, and using the second processing method to process the shear wave propagating circumferentially along the object to be detected comprises: based on the displacement of any one of the data points, Obtaining the displacement-time curves obtained by the shear wave front arriving at the position at different times; performing a two-dimensional Fourier transform on the displacement-time curves to obtain a Fourier transform result, which includes Frequency values and all wave values corresponding to any frequency value; for an angle of interest, a shear wave dispersion curve is established based on the maximum wave value corresponding to each of the frequency values in the angle of interest.

可选地,所述对所述剪切波弹性成像进行可视化处理包括:对所述极坐标系的剪切波弹性成像进行空间插值,以得到所述剪切波弹性成像的可视化数据。Optionally, the performing visualization processing on the shear wave elastography includes: performing spatial interpolation on the shear wave elastography in the polar coordinate system, so as to obtain the visualization data of the shear wave elastography.

根据本发明另一方面,提供了剪切波弹性成像装置,所述装置包括:数据获取单元,用于获取待检测对象的采样数据,所述采样数据包括直角坐标系的超声图像数据;坐标转换单元,用于对所述直角坐标系的超声图像数据进行坐标转换,以将所述直角坐标系的超声图像数据转换为极坐标系的超声图像数据;处理单元,用于通过预设处理方法对所述极坐标系的超声图像数据进行处理,以得到用于表征所述待检测对象的弹性模量的剪切波弹性成像;可视化单元,用于对所述剪切波弹性成像进行可视化处理,以用于显示所述待检测对象的弹性模量。According to another aspect of the present invention, a shear wave elastography device is provided, and the device includes: a data acquisition unit for acquiring sampling data of an object to be detected, the sampling data including ultrasonic image data in a Cartesian coordinate system; coordinate conversion A unit for performing coordinate transformation on the ultrasonic image data of the rectangular coordinate system, so as to convert the ultrasonic image data of the rectangular coordinate system into ultrasonic image data of the polar coordinate system; a processing unit for processing the ultrasonic image data by a preset processing method The ultrasonic image data in the polar coordinate system is processed to obtain shear wave elastography for characterizing the elastic modulus of the object to be detected; a visualization unit is used for visualizing the shear wave elastography, used to display the elastic modulus of the object to be detected.

本发明实施例提供的剪切波弹性成像方法和装置,基于坐标变换(直角坐标系转换为极坐标系)实现待检测对象的剪切波弹性成像,可以对待检测对象的长轴切面的剪切波和短轴切面的剪切波进行处理,以得到待检测对象的准确的弹性定量,提高对待检测对象的病理检测精度。The shear wave elastography method and device provided by the embodiments of the present invention realize the shear wave elastography of the object to be detected based on coordinate transformation (transformation from a rectangular coordinate system to a polar coordinate system), and can shear the long axis section of the object to be detected. The wave and the shear wave of the short-axis section are processed to obtain accurate elastic quantification of the object to be detected, and to improve the pathological detection accuracy of the object to be detected.

附图说明Description of drawings

通过结合附图对本发明实施例进行更详细的描述,本发明的上述以及其它目的、特征和优势将变得更加明显。附图用来提供对本发明实施例的进一步理解,并且构成说明书的一部分,与本发明实施例一起用于解释本发明,并不构成对本发明的限制。在附图中,相同的参考标号通常代表相同部件或步骤。The above and other objects, features and advantages of the present invention will become more apparent by describing the embodiments of the present invention in more detail with reference to the accompanying drawings. The accompanying drawings are used to provide a further understanding of the embodiments of the present invention, and constitute a part of the specification, and are used together with the embodiments of the present invention to explain the present invention, and do not constitute limitations to the present invention. In the drawings, the same reference numerals generally represent the same components or steps.

图1示出根据本发明一个实施例的剪切波弹性成像方法的流程示意图;FIG. 1 shows a schematic flow diagram of a shear wave elastography method according to an embodiment of the present invention;

图2示出根据本发明一个实施例的空间插值实现过程的示意图;Fig. 2 shows a schematic diagram of a spatial interpolation implementation process according to an embodiment of the present invention;

图3示出根据本发明一个实施例的斑点追踪的原理示意图;Fig. 3 shows a schematic diagram of the principle of speckle tracking according to an embodiment of the present invention;

图4示出根据本发明一个实施例的剪切波弹性成像装置的结构框图。Fig. 4 shows a structural block diagram of a shear wave elastography device according to an embodiment of the present invention.

具体实施方式Detailed ways

为了使得本发明的目的、技术方案和优点更为明显,下面将参照附图详细描述根据本发明的示例实施例。显然,所描述的实施例仅仅是本发明的一部分实施例,而不是本发明的全部实施例,应理解,本发明不受这里描述的示例实施例的限制。基于本发明中描述的本发明实施例,本领域技术人员在没有付出创造性劳动的情况下所得到的所有其它实施例都应落入本发明的保护范围之内。In order to make the objects, technical solutions and advantages of the present invention more apparent, exemplary embodiments according to the present invention will be described in detail below with reference to the accompanying drawings. Apparently, the described embodiments are only some embodiments of the present invention, rather than all embodiments of the present invention, and it should be understood that the present invention is not limited by the exemplary embodiments described here. Based on the embodiments of the present invention described in the present invention, all other embodiments obtained by those skilled in the art without creative effort shall fall within the protection scope of the present invention.

基于声辐射力的剪切波弹性成像技术是一种评估组织硬度的超声弹性成像技术。其基本原理为:由探头向生物体的软组织发射高能量的超声波,产生声辐射力,在声辐射力和组织的剪切应力的作用下,特定区域内的软组织会产生向四周传播的振动,从而产生剪切波,由于生物体软组织的硬度和剪切波速度存在着关联关系,因此可以通过检测剪切波的速度以分析生物体软组织的硬度。Acoustic radiation force-based shear wave elastography is an ultrasound elastography technique for assessing tissue stiffness. The basic principle is: the probe emits high-energy ultrasonic waves to the soft tissue of the living body to generate an acoustic radiation force. Under the action of the acoustic radiation force and the shear stress of the tissue, the soft tissue in a specific area will generate vibrations that propagate around. Thus, shear waves are generated. Since there is a correlation between the hardness of the soft tissue of the organism and the velocity of the shear wave, the hardness of the soft tissue of the organism can be analyzed by detecting the velocity of the shear wave.

相关技术的剪切波弹性成像的可以包括两个关键点:1、考虑轴向位移,即剪切波的振动方向;2、方向滤波器设置时仅考虑某一个感兴趣的方向。对于像血管这样的软组织,相关技术中的剪切波弹性成像仅能对其长轴切面的剪切波成像进行处理,而不能处理其短轴切面的剪切波弹性成像。但对于血管短轴切面的剪切波弹性成像,需要考虑的是径向位移而非轴向位移,以及需要沿着环向滤波的方向滤波器。因此,通过相关技术的剪切波弹性成像,很难准确地对血管进行弹性定量,而降低血管的病理检测精度。The shear wave elastography of the related art may include two key points: 1. Consider the axial displacement, that is, the vibration direction of the shear wave; 2. Only consider a certain direction of interest when setting the direction filter. For soft tissues such as blood vessels, the shear wave elastography in the related art can only process the shear wave imaging of the long axis section, but not the shear wave elastography of the short axis section. However, for shear wave elastography in the short-axis view of vessels, radial displacement rather than axial displacement needs to be considered, and a directional filter along the circumferential filter is required. Therefore, it is difficult to accurately quantify the elasticity of blood vessels through the shear wave elastography of the related art, which reduces the accuracy of pathological detection of blood vessels.

为了解决上文所述的问题,本发明实施例提出一种剪切波弹性成像方法和装置,基于坐标变换实现待检测对象的剪切波弹性成像,得到待检测对象的准确的弹性定量,提高对待检测对象的病理检测精度。In order to solve the above-mentioned problems, the embodiment of the present invention proposes a shear wave elastography method and device, which realizes shear wave elastography of the object to be detected based on coordinate transformation, obtains accurate elastic quantification of the object to be detected, and improves Pathological detection accuracy of the object to be detected.

下面将结合附图对本发明提供的剪切波弹性成像方法和装置进行详细描述,以使本领域技术人员能够清楚、准确地理解本发明的技术方案。The shear wave elastography method and device provided by the present invention will be described in detail below with reference to the accompanying drawings, so that those skilled in the art can clearly and accurately understand the technical solution of the present invention.

图1示出根据本发明一个实施例的剪切波弹性成像方法的流程示意图。如图1所示,本发明实施例提供的一种剪切波弹性成像方法包括如下步骤:Fig. 1 shows a schematic flowchart of a shear wave elastography method according to an embodiment of the present invention. As shown in Figure 1, a shear wave elastography method provided by an embodiment of the present invention includes the following steps:

步骤110,获取待检测对象的采样数据,其中,采样数据包括直角坐标系的超声图像数据。Step 110, acquiring sampling data of the object to be detected, wherein the sampling data includes ultrasonic image data in a Cartesian coordinate system.

在本步骤中,可以利用声辐射力激励待检测对象的感兴趣区域,对感兴趣区域进行超高速超声成像,以得到待检测对象的感兴趣区域的超声图像数据。示例性地,超声图像数据可以包括RF(Radio Frequency,射频)数据、包络数据、B模数据中的至少一种。In this step, the region of interest of the object to be detected may be excited by the force of acoustic radiation, and ultra-high-speed ultrasonic imaging is performed on the region of interest to obtain ultrasonic image data of the region of interest of the object to be detected. Exemplarily, the ultrasound image data may include at least one of RF (Radio Frequency, radio frequency) data, envelope data, and B-mode data.

以血管为例,血管内弹性成像可以利用气囊、血压变化或者外部挤压来激励血管,估计血管的运动即位移(一般为纵向),得到血管的应变分布,从而表征血管的弹性。在本发明实施例中,可以利用声辐射力激励血管,得到血管的超声图像数据。示例性地,在本步骤中获得的超声图像数据为直角坐标系的超声图像数据。Taking blood vessels as an example, intravascular elastography can use balloons, blood pressure changes or external extrusion to stimulate blood vessels, estimate the movement of blood vessels, that is, displacement (generally longitudinal), obtain the strain distribution of blood vessels, and thus characterize the elasticity of blood vessels. In the embodiment of the present invention, the blood vessel can be excited by the force of acoustic radiation to obtain the ultrasonic image data of the blood vessel. Exemplarily, the ultrasonic image data obtained in this step is ultrasonic image data in a Cartesian coordinate system.

步骤120,对直角坐标系的超声图像数据进行坐标转换,以将直角坐标系的超声图像数据转换为极坐标系的超声图像数据。Step 120, performing coordinate transformation on the ultrasonic image data in the rectangular coordinate system, so as to convert the ultrasonic image data in the rectangular coordinate system into ultrasonic image data in the polar coordinate system.

在本步骤中,可以通过坐标变换将直角坐标系的超声图像数据转换为极坐标系的超声图像数据。可以通过空间插值法实现直角坐标系至极坐标系的坐标转换。作为一个示例,可以将待检测对象的几何中心确定为极坐标原点,根据预设采样率分别对极坐标系的角度方向和半径方向进行数据采样,以获得采样数据点,用直角坐标系的超声图像数据对采用数据点进行空间插值,以得到极坐标系的超声图像数据。示例性地,在极坐标系中,横坐标为角度,纵坐标为半径。关于确定待检测对象的几何中心,例如可以通过手动选择的方式确定,也可以通过对待检测对象的图像进行图像自动分割以实现对其几何中心的选择。In this step, the ultrasonic image data in the rectangular coordinate system may be converted into ultrasonic image data in the polar coordinate system through coordinate transformation. The coordinate conversion from the Cartesian coordinate system to the polar coordinate system can be realized by spatial interpolation. As an example, the geometric center of the object to be detected can be determined as the polar coordinate origin, and data sampling is performed on the angular direction and radial direction of the polar coordinate system according to the preset sampling rate to obtain sampling data points. The image data is used to perform spatial interpolation on the data points to obtain the ultrasonic image data in the polar coordinate system. Exemplarily, in the polar coordinate system, the abscissa is an angle, and the ordinate is a radius. With regard to determining the geometric center of the object to be detected, for example, it may be determined by manual selection, or the geometric center may be selected by performing automatic image segmentation on the image of the object to be detected.

仍以血管为例,将血管的几何中心(例如,圆心)作为极坐标原点,从原点发射线状采样,其中,沿着射线方向为半径方向,垂直于射线方向为角度方向。在本发明实施例中,根据预设采样率对血管的半径方向和角度方向均进行采样,以获得采用数据点,再利用直角坐标系的超声图像数据对采用数据点进行空间插值,实现直角坐标系到极坐标系的坐标转换,从而得到极坐标系的超声图像数据。预设采样率例如可以是极坐标系的任一个方向采集的数据点的数量,其可以根据实际需求设定,在本发明实施例中不对此进行限定。空间插值法可以例如采用线性插值、多项式拟合插值等任一种实现,本发明不对此进行限制。Still taking the blood vessel as an example, the geometric center of the blood vessel (for example, the center of a circle) is taken as the origin of polar coordinates, and linear sampling is emitted from the origin, wherein the direction along the ray is the radial direction, and the direction perpendicular to the ray is the angular direction. In the embodiment of the present invention, both the radial direction and the angular direction of the blood vessel are sampled according to the preset sampling rate to obtain the adopted data points, and then the ultrasonic image data of the Cartesian coordinate system is used to perform spatial interpolation on the adopted data points to realize Cartesian coordinates Coordinate transformation from the polar coordinate system to obtain the ultrasonic image data in the polar coordinate system. The preset sampling rate may be, for example, the number of data points collected in any direction of the polar coordinate system, which may be set according to actual requirements, and is not limited in this embodiment of the present invention. The spatial interpolation method may be implemented by, for example, linear interpolation, polynomial fitting interpolation, etc., and the present invention is not limited thereto.

下面将结合图2所示的本发明实施例的空间插值实现过程的示意图,可以理解的是,图2所示的插值实施例仅为示例,而不造成对本发明的限制。图2中以二维空间插值为例,设直角坐标系中的任意一数据点的坐标可以表示为(x,y),在确定待检测对象的几何中心(例如,血管的圆心)后,任意一数据点在极坐标中表示可以为(r,θ)。图中实心的点代表直角坐标系的超声图像数据,空心的点代表圆心确定后极坐标下需要获得的数据(极坐标系下的超声图像数据),可以通过对半径方向和角度方向均匀采样获得。可以根据实心点的信息通过空间插值得到空心的点的信息。The following will refer to the schematic diagram of the implementation process of spatial interpolation in the embodiment of the present invention shown in FIG. 2 . It can be understood that the interpolation embodiment shown in FIG. 2 is only an example and does not limit the present invention. In Figure 2, two-dimensional space interpolation is taken as an example. The coordinates of any data point in the Cartesian coordinate system can be expressed as (x, y). After determining the geometric center of the object to be detected (for example, the center of the blood vessel), any A data point may be expressed as (r, θ) in polar coordinates. The solid points in the figure represent the ultrasonic image data in the Cartesian coordinate system, and the hollow points represent the data that needs to be obtained in polar coordinates after the center of the circle is determined (ultrasonic image data in the polar coordinate system), which can be obtained by uniform sampling in the radial direction and angular direction . The information of the hollow points can be obtained through spatial interpolation according to the information of the solid points.

步骤130,通过预设处理方法对极坐标系的超声图像数据进行处理,以得到用于表征待检测对象的弹性模量的剪切波弹性成像。In step 130, the ultrasonic image data in the polar coordinate system is processed by a preset processing method to obtain shear wave elastography used to characterize the elastic modulus of the object to be detected.

剪切波弹性成像是通过检测声辐射力激发组织而产生剪切波的传播进行成像的方法。通过对剪切波弹性成像进行运算处理可以求得组织的剪切模量,用以对组织病理进行分析。Shear wave elastography is a method of imaging by detecting the propagation of shear waves generated by the excitation of tissue by the force of acoustic radiation. The shear modulus of the tissue can be obtained by computing the shear wave elastography, which can be used to analyze the histopathology.

在本步骤中,可以通过预先设定的处理方法对极坐标系的超声图像数据进行处理,从而得到待检测对象的剪切波弹性成像。根据本发明一实施例,可以通过第一处理方法处理极坐标系的超声图像数据,以得到极坐标系的超声图像数据的任一数据点的位移和沿所述待检测对象的感兴趣方向传播的剪切波,以及基于任一数据点的位移通过第二处理方法对沿待检测对象环向传播的剪切波进行处理,以得到剪切波频散曲线。In this step, the ultrasonic image data in the polar coordinate system may be processed by a preset processing method, so as to obtain the shear wave elastography of the object to be detected. According to an embodiment of the present invention, the ultrasonic image data in the polar coordinate system can be processed by the first processing method, so as to obtain the displacement and propagation of any data point of the ultrasonic image data in the polar coordinate system along the direction of interest of the object to be detected The shear wave and the shear wave propagating along the circumferential direction of the object to be detected are processed by a second processing method based on the displacement of any data point, so as to obtain a shear wave dispersion curve.

进一步地,在一些实施例中,采用第一处理方法对极坐标系的超声图像数据的处理可以包括如下步骤:Further, in some embodiments, the processing of the ultrasonic image data in the polar coordinate system by the first processing method may include the following steps:

步骤A、对极坐标系的超声图像数据进行斑点追踪,以得到任一数据点的在极坐标系中的径向位移和环向位移。Step A, performing speckle tracking on the ultrasonic image data in the polar coordinate system to obtain the radial displacement and the circumferential displacement of any data point in the polar coordinate system.

在该步骤中即可以通过斑点追踪实现位移估计,其中,斑点追踪的实现方法包括不限互相关、自相关、光流法等块运动匹配的所有可以得到极坐标内二维位移的方法。In this step, displacement estimation can be realized by speckle tracking, wherein the implementation methods of speckle tracking include all methods of block motion matching such as cross-correlation, auto-correlation, and optical flow method that can obtain two-dimensional displacement in polar coordinates.

示例性地,可以对极坐标系的超声图像数据中的任一数据点进行加窗处理,得到对应该数据点的数据窗,当连续两帧的超声图像数据中数据窗的相关性(评价相关性的参数诸多,例如,可以是自相关系数,也可以是互相关系数等)最大时,确定该数据点的在极坐标系中的径向位移和环向位移。在本发明实施例中,相关性系数可以通过自相关、互相关、绝对误差和、幅度差平方和以及光流法等方式计算确定,可以理解,相关性系数的计算不限于这几种实现方式,还可以通过其他块匹配的运动估计算法实现,在此不再一一赘述。如图3所示的斑点追踪的原理示意图。如图3的a图像中,确定一感兴趣区域(如图中数据窗位置),由于剪切波是连续运动的,因此需要在至少两帧图像中对其进行搜索跟踪,如图3中的b和c图像,当连续两帧的超声图像数据中数据窗的相关性最大时(可以理解为匹配度最好的位置,即图3中d图像中的最佳匹配位置),分别得到沿角度方向和半径方向的位移,即径向位移和环向位移,如图3中的d图像的标识的两处位移。Exemplarily, any data point in the ultrasonic image data of the polar coordinate system can be windowed to obtain the data window corresponding to the data point. When the correlation of the data window in the ultrasonic image data of two consecutive frames (evaluation correlation There are many parameters, for example, it can be the autocorrelation coefficient, or the cross-correlation coefficient, etc.) When the maximum, determine the radial displacement and circumferential displacement of the data point in the polar coordinate system. In the embodiment of the present invention, the correlation coefficient can be calculated and determined by means of autocorrelation, cross-correlation, absolute error sum, amplitude difference square sum, and optical flow method. It can be understood that the calculation of the correlation coefficient is not limited to these several implementation methods , can also be realized by other block-matching motion estimation algorithms, which will not be repeated here. The schematic diagram of the principle of speckle tracking is shown in Fig. 3 . As shown in image a of Figure 3, determine a region of interest (as shown in the data window position), since the shear wave is in continuous motion, it needs to be searched and tracked in at least two frames of images, as shown in Figure 3 For images b and c, when the correlation of the data window in two consecutive frames of ultrasound image data is the largest (it can be understood as the position with the best matching degree, that is, the best matching position in image d in Figure 3), the angles along the The displacement in the direction and radial direction, that is, the radial displacement and the circumferential displacement, are the two displacements identified in the d image in Fig. 3 .

步骤B、基于径向位移和环向位移建立位移时间曲线。Step B, establishing a displacement-time curve based on the radial displacement and the circumferential displacement.

示例性地,例如可以在待检测对象的感兴趣区域的传播路径上,任意一个时刻对应波前到达的空间位置,将连续的若干个时刻整合在一起,一个维度代表时间,另一个维度代表空间位置,由于波前传播是连续的,因此可以在二维空间内确定波前传播的情况,即建立位移时间曲线。Exemplarily, for example, on the propagation path of the region of interest of the object to be detected, any moment can correspond to the spatial position where the wavefront arrives, and several consecutive moments can be integrated, one dimension represents time, and the other dimension represents space Since the wavefront propagation is continuous, the situation of the wavefront propagation can be determined in two-dimensional space, that is, the displacement time curve can be established.

步骤C、对位移时间曲线进行二维傅里叶变换,以得到傅里叶变换结果,其中,傅里叶变换结果的不同角度范围表示剪切波的不同方向的运动信息。Step C, performing a two-dimensional Fourier transform on the displacement-time curve to obtain a Fourier transform result, wherein different angle ranges of the Fourier transform result represent motion information of shear waves in different directions.

步骤D、对感兴趣的角度进行加窗处理,后经过逆傅里叶变换,以得到沿待检测对象的感兴趣方向传播的剪切波。Step D, perform windowing processing on the angle of interest, and then undergo an inverse Fourier transform to obtain a shear wave propagating along the direction of interest of the object to be detected.

步骤C和步骤D实现方向滤波,即对位移时间曲线进行傅里叶变换、逆傅里叶变换、方向加窗处理得到感兴趣方向传播的剪切波。Steps C and D implement direction filtering, that is, Fourier transform, inverse Fourier transform, and direction windowing are performed on the displacement-time curve to obtain shear waves propagating in the direction of interest.

而步骤130的基于任一数据点的位移通过第二处理方法对沿待检测对象环向传播的剪切波进行处理的步骤可以包括:基于任一数据点的位移,得到剪切波波前在不同时间到达位置得到的位移时间曲线,对位移时间曲线进行二维傅里叶变换,以得到傅里叶变换结果,傅里叶变换结果中包括频率值和任一频率值对应的所有波数值,针对感兴趣的角度,基于感兴趣的角度中每个频率值对应的最大波数值建立剪切波频散曲线。In step 130, the step of processing the shear wave propagating in the circumferential direction of the object to be detected by the second processing method based on the displacement of any data point may include: based on the displacement of any data point, obtaining the shear wave front at The displacement-time curve obtained by arriving at the position at different times, two-dimensional Fourier transform is performed on the displacement-time curve to obtain the Fourier transform result, which includes the frequency value and all wave values corresponding to any frequency value, For the angle of interest, a shear wave dispersion curve is established based on the maximum wave value corresponding to each frequency value in the angle of interest.

示例性地,选择感兴趣的角度方向,例如,当感兴趣的角度方向向右时,对应的傅里叶变换中的信息位于第一象限,其中,傅里叶变换中的信息分别包括频率信息和波数信息(频率值和波数值),取任一个频率值下最大的波数值,得到待检测对象的剪切波频散曲线,即不同频率的剪切波相速度曲线。基于剪切波的频散曲线评价待检测对象的剪切模量,准确率更高,而对于像血管这样的待检测对象,基于极坐标系下对感兴趣的角度的选择,可以同时处理长轴切面和短轴切面,弥补相关技术的弊端,得到更精准的待检测对象的弹性定量。Exemplarily, the angle direction of interest is selected, for example, when the angle direction of interest is to the right, the information in the corresponding Fourier transform is located in the first quadrant, wherein the information in the Fourier transform includes frequency information respectively And wave number information (frequency value and wave value), take the largest wave value under any frequency value to obtain the shear wave dispersion curve of the object to be detected, that is, the shear wave phase velocity curve of different frequencies. Based on the shear wave dispersion curve to evaluate the shear modulus of the object to be detected, the accuracy rate is higher, and for the object to be detected such as blood vessels, based on the selection of the angle of interest in the polar coordinate system, it can simultaneously process long Axial section and short-axis section make up for the disadvantages of related technologies and obtain more accurate elastic quantification of the object to be detected.

根据本发明另一实施例,进一步地,本步骤还可以包括基于任一数据点的位移和沿待检测对象环向传播的剪切波得到剪切波的传输速度。示例性地,在极坐标系中,根据剪切波波前在不同时间到达位置对剪切波波速进行测量,从而得到剪切波的传播速度。应用该实施例,结合剪切波的传播速度及剪切波的频散曲线评价待检测对象的剪切模量,两者可以相辅相成,进一步提高待检测对象的弹性定量的精准度。According to another embodiment of the present invention, further, this step may further include obtaining the transmission velocity of the shear wave based on the displacement of any data point and the shear wave propagating along the circumferential direction of the object to be detected. Exemplarily, in the polar coordinate system, the velocity of the shear wave is measured according to the arrival position of the shear wave front at different times, so as to obtain the propagation velocity of the shear wave. Applying this embodiment, the shear modulus of the object to be detected can be evaluated in combination with the propagation velocity of the shear wave and the dispersion curve of the shear wave. The two can complement each other and further improve the accuracy of the elastic quantification of the object to be detected.

步骤140,对剪切波弹性成像进行可视化处理,以用于显示待检测对象的弹性模量。Step 140, performing visualization processing on the shear wave elastography, so as to display the elastic modulus of the object to be detected.

由于位移估计、方向滤波等都是在极坐标下进行,得到方向滤波后的剪切波传播后,可以对剪切波传播的数据(例如,可以包括散射子震动位移、速度、加速度等)进行坐标变换,即由极坐标转换成直角坐标,转换原理及过程与步骤120相同,在此不再赘述,通过坐标转换实现剪切波传播的可视化,即实现剪切波弹性成像的可视化处理。Since the displacement estimation and direction filtering are performed in polar coordinates, after obtaining the direction-filtered shear wave propagation, the shear wave propagation data (for example, including the vibration displacement, velocity, acceleration, etc. of the scatterers) can be calculated Coordinate transformation, that is, transforming from polar coordinates to rectangular coordinates, the transformation principle and process are the same as step 120, and will not be repeated here. The visualization of shear wave propagation is realized through coordinate transformation, that is, the visualization of shear wave elastography is realized.

应用本发明实施例提供的剪切波弹性成像方法,基于坐标变换(直角坐标系转换为极坐标系)实现待检测对象的剪切波弹性成像,可以对待检测对象的长轴切面的剪切波和短轴切面的剪切波进行处理,以得到待检测对象的准确的弹性定量,提高对待检测对象的病理检测精度。Applying the shear wave elastography method provided by the embodiment of the present invention, based on the coordinate transformation (rectangular coordinate system is converted into a polar coordinate system), the shear wave elastography of the object to be detected can be realized, and the shear wave elastography of the long axis section of the object to be detected can be realized. and the shear wave of the short-axis section to obtain accurate elastic quantification of the object to be detected and improve the pathological detection accuracy of the object to be detected.

此外,通过方向滤波处理,可以得到剪切波在待检测对象(例如,血管壁)径向的运动,并可以有效的去除待检测对象(例如,沿血管壁)环向的反射波,为待检测对象的弹性定量研究提供基础。In addition, through the direction filtering process, the movement of the shear wave in the radial direction of the object to be detected (for example, the blood vessel wall) can be obtained, and the reflected wave in the circumferential direction of the object to be detected (for example, along the blood vessel wall) can be effectively removed. Provides the basis for the elastic quantitative study of the detection object.

另外,通过待检测对象(例如血管)横截面的剪切波成像,进一步可以得到管壁的剪切波速度、频散曲线,结合剪切波传播速度和频散曲线对待检测对象的弹性进行定量测量,可以提高测量精度和准确度。In addition, through the shear wave imaging of the cross-section of the object to be detected (such as a blood vessel), the shear wave velocity and dispersion curve of the tube wall can be further obtained, and the elasticity of the object to be detected can be quantified in combination with the shear wave propagation velocity and dispersion curve Measurement can improve measurement precision and accuracy.

本发明还提供一种应用上述剪切波弹性成像方法的剪切波弹性成像装置。图4示出根据本发明一个实施例的剪切波弹性成像装置的结构框图。如图4所示,剪切波弹性成像装置可以包括数据获取单元410、坐标转换单元420、处理单元430和可视化单元440。示例性地,数据获取单元410、坐标转换单元420、处理单元430和可视化单元440均可以设置在计算机中,由计算机的运算处理单元实现。The present invention also provides a shear wave elastography device applying the above shear wave elastography method. Fig. 4 shows a structural block diagram of a shear wave elastography device according to an embodiment of the present invention. As shown in FIG. 4 , the shear wave elastography device may include a data acquisition unit 410 , a coordinate conversion unit 420 , a processing unit 430 and a visualization unit 440 . Exemplarily, the data acquisition unit 410 , the coordinate conversion unit 420 , the processing unit 430 and the visualization unit 440 can all be set in a computer and realized by an operation processing unit of the computer.

数据获取单元410可以用于获取待检测对象的采样数据,其中,采样数据包括直角坐标系的超声图像数据。The data acquiring unit 410 may be used to acquire sampled data of the object to be detected, wherein the sampled data includes ultrasonic image data in a Cartesian coordinate system.

坐标转换单元420可以用于对数据获取单元410获取的直角坐标系的超声图像数据进行坐标转换,以将超直角坐标系的超声图像数据转换为极坐标系的超声图像数据。The coordinate conversion unit 420 can be used to perform coordinate conversion on the ultrasonic image data in the rectangular coordinate system acquired by the data acquisition unit 410, so as to convert the ultrasonic image data in the super rectangular coordinate system into the ultrasonic image data in the polar coordinate system.

处理单元430可以用于通过预设处理方法对坐标转换单元420得到的极坐标系的超声图像数据进行处理,以得到用于表征待检测对象的弹性模量的剪切波弹性成像。The processing unit 430 may be configured to process the ultrasonic image data in the polar coordinate system obtained by the coordinate conversion unit 420 through a preset processing method, so as to obtain shear wave elastography used to characterize the elastic modulus of the object to be detected.

可视化单元440可以用于对处理单元430得到的剪切波弹性成像进行可视化处理,以用于显示所述待检测对象的弹性模量。The visualization unit 440 may be configured to perform visualization processing on the shear wave elastography obtained by the processing unit 430, so as to display the elastic modulus of the object to be detected.

应用本发明实施例提供的剪切波弹性成像装置,可以基于坐标变换(直角坐标系转换为极坐标系)实现待检测对象的剪切波弹性成像,可以对待检测对象的长轴切面的剪切波和短轴切面的剪切波进行处理,以得到待检测对象的准确的弹性定量,提高对待检测对象的病理检测精度。By applying the shear wave elastography device provided by the embodiment of the present invention, the shear wave elastography of the object to be detected can be realized based on coordinate transformation (transformation from a rectangular coordinate system to a polar coordinate system), and the shear wave elastography of the long axis section of the object to be detected can be realized. The wave and the shear wave of the short-axis section are processed to obtain accurate elastic quantification of the object to be detected, and to improve the pathological detection accuracy of the object to be detected.

尽管本文已经参考附图描述了示例实施例,应理解上述示例实施例仅仅是示例性的,并且不意图将本发明的范围限制于此。本领域普通技术人员可以在其中进行各种改变和修改,而不偏离本发明的范围和精神。所有这些改变和修改意在被包括在所附权利要求所要求的本发明的范围之内。Although example embodiments have been described herein with reference to the accompanying drawings, it should be understood that the above example embodiments are illustrative only and are not intended to limit the scope of the invention thereto. Various changes and modifications can be made therein by those skilled in the art without departing from the scope and spirit of the invention. All such changes and modifications are intended to be included within the scope of the invention as claimed in the appended claims.

本领域普通技术人员可以意识到,结合本文中所公开的实施例描述的各示例的单元及算法步骤,能够以电子硬件、或者计算机软件和电子硬件的结合来实现。这些功能究竟以硬件还是软件方式来执行,取决于技术方案的特定应用和设计约束条件。专业技术人员可以对每个特定的应用来使用不同方法来实现所描述的功能,但是这种实现不应认为超出本发明的范围。Those skilled in the art can appreciate that the units and algorithm steps of the examples described in conjunction with the embodiments disclosed herein can be implemented by electronic hardware, or a combination of computer software and electronic hardware. Whether these functions are executed by hardware or software depends on the specific application and design constraints of the technical solution. Those skilled in the art may use different methods to implement the described functions for each specific application, but such implementation should not be regarded as exceeding the scope of the present invention.

在本申请所提供的几个实施例中,应该理解到,所揭露的设备和方法,可以通过其它的方式实现。例如,以上所描述的设备实施例仅仅是示意性的,例如,单元的划分,仅仅为一种逻辑功能划分,实际实现时可以有另外的划分方式,例如多个单元或组件可以结合或者可以集成到另一个设备,或一些特征可以忽略,或不执行。In the several embodiments provided in this application, it should be understood that the disclosed devices and methods may be implemented in other ways. For example, the device embodiments described above are only illustrative. For example, the division of units is only a logical function division. In actual implementation, there may be other division methods, for example, multiple units or components can be combined or integrated. to another device, or some features may be ignored, or not implemented.

在此处所提供的说明书中,说明了大量具体细节。然而,能够理解,本发明的实施例可以在没有这些具体细节的情况下实践。在一些实例中,并未详细示出公知的方法、结构和技术,以便不模糊对本说明书的理解。In the description provided herein, numerous specific details are set forth. However, it is understood that embodiments of the invention may be practiced without these specific details. In some instances, well-known methods, structures and techniques have not been shown in detail in order not to obscure the understanding of this description.

类似地,应当理解,为了精简本发明并帮助理解各个发明方面中的一个或多个,在对本发明的示例性实施例的描述中,本发明的各个特征有时被一起分组到单个实施例、图、或者对其的描述中。然而,并不应将该本发明的方法解释成反映如下意图:即所要求保护的本发明要求比在每个权利要求中所明确记载的特征更多的特征。更确切地说,如相应的权利要求书所反映的那样,其发明点在于可以用少于某个公开的单个实施例的所有特征的特征来解决相应的技术问题。因此,遵循具体实施方式的权利要求书由此明确地并入该具体实施方式,其中每个权利要求本身都作为本发明的单独实施例。Similarly, it should be understood that in the description of the exemplary embodiments of the invention, in order to streamline the disclosure and to facilitate an understanding of one or more of the various inventive aspects, various features of the invention are sometimes grouped together in a single embodiment, figure , or in its description. This method of disclosure, however, is not to be interpreted as reflecting an intention that the claimed invention requires more features than are expressly recited in each claim. Rather, as the corresponding claims reflect, the inventive point lies in that the corresponding technical problem may be solved by using less than all features of a single disclosed embodiment. Thus, the claims following the Detailed Description are hereby expressly incorporated into this Detailed Description, with each claim standing on its own as a separate embodiment of this invention.

本领域的技术人员可以理解,除了特征之间相互排斥之外,可以采用任何组合对本说明书(包括伴随的权利要求、摘要和附图)中公开的所有特征以及如此公开的任何方法或者设备的所有过程或单元进行组合。除非另外明确陈述,本说明书(包括伴随的权利要求、摘要和附图)中公开的每个特征可以由提供相同、等同或相似目的的替代特征来代替。It will be appreciated by those skilled in the art that all features disclosed in this specification (including accompanying claims, abstract and drawings) and all features of any method or apparatus so disclosed may be used in any combination, except where the features are mutually exclusive. Processes or units are combined. Each feature disclosed in this specification (including accompanying claims, abstract and drawings) may be replaced by alternative features serving the same, equivalent or similar purpose, unless expressly stated otherwise.

此外,本领域的技术人员能够理解,尽管在此所述的一些实施例包括其它实施例中所包括的某些特征而不是其它特征,但是不同实施例的特征的组合意味着处于本发明的范围之内并且形成不同的实施例。例如,在权利要求书中,所要求保护的实施例的任意之一都可以以任意的组合方式来使用。Furthermore, those skilled in the art will understand that although some embodiments described herein include some features included in other embodiments but not others, combinations of features from different embodiments are meant to be within the scope of the invention. and form different embodiments. For example, in the claims, any one of the claimed embodiments can be used in any combination.

本发明的各个部件实施例可以以硬件实现,或者以在一个或者多个处理器上运行的软件模块实现,或者以它们的组合实现。本领域的技术人员应当理解,可以在实践中使用微处理器或者数字信号处理器(DSP)来实现根据本发明实施例的导线悬挂点定位装置中的一些模块的一些或者全部功能。本发明还可以实现为用于执行这里所描述的方法的一部分或者全部的装置程序(例如,计算机程序和计算机程序产品)。这样的实现本发明的程序可以存储在计算机可读介质上,或者可以具有一个或者多个信号的形式。这样的信号可以从因特网网站上下载得到,或者在载体信号上提供,或者以任何其他形式提供。The various component embodiments of the present invention may be implemented in hardware, or in software modules running on one or more processors, or in a combination thereof. Those skilled in the art should understand that a microprocessor or a digital signal processor (DSP) can be used in practice to realize some or all functions of some modules in the wire suspension point positioning device according to the embodiment of the present invention. The present invention can also be implemented as an apparatus program (for example, a computer program and a computer program product) for performing a part or all of the methods described herein. Such a program for realizing the present invention may be stored on a computer-readable medium, or may be in the form of one or more signals. Such a signal may be downloaded from an Internet site, or provided on a carrier signal, or provided in any other form.

应该注意的是上述实施例对本发明进行说明而不是对本发明进行限制,并且本领域技术人员在不脱离所附权利要求的范围的情况下可设计出替换实施例。在权利要求中,不应将位于括号之间的任何参考符号构造成对权利要求的限制。单词“包含”不排除存在未列在权利要求中的组件或步骤。位于组件之前的单词“一”或“一个”不排除存在多个这样的组件。本发明可以借助于包括有若干不同组件的硬件以及借助于适当编程的计算机来实现。在列举了若干装置的单元权利要求中,这些装置中的若干个可以是通过同一个硬件项来具体体现。单词第一、第二、以及第三等的使用不表示任何顺序。可将这些单词解释为名称。It should be noted that the above-mentioned embodiments illustrate rather than limit the invention, and that those skilled in the art will be able to design alternative embodiments without departing from the scope of the appended claims. In the claims, any reference signs placed between parentheses shall not be construed as limiting the claim. The word "comprising" does not exclude the presence of components or steps not listed in a claim. The word "a" or "an" preceding an element does not exclude the presence of a plurality of such elements. The invention can be implemented by means of hardware comprising several distinct components, and by means of a suitably programmed computer. In a unit claim enumerating several means, several of these means can be embodied by one and the same item of hardware. The use of the words first, second, and third, etc. does not indicate any order. These words can be interpreted as names.

以上所述,仅为本发明的具体实施方式或对具体实施方式的说明,本发明的保护范围并不局限于此,任何熟悉本技术领域的技术人员在本发明揭露的技术范围内,可轻易想到变化或替换,都应涵盖在本发明的保护范围之内。本发明的保护范围应以权利要求的保护范围为准。The above is only a specific embodiment of the present invention or a description of the specific embodiment, and the protection scope of the present invention is not limited thereto. Any person familiar with the technical field can easily Any changes or substitutions that come to mind should be covered within the protection scope of the present invention. The protection scope of the present invention should be based on the protection scope of the claims.

Claims (8)

1. A method of shear wave elastography, the method comprising:
acquiring sampling data of an object to be detected, wherein the sampling data comprises ultrasonic image data of a rectangular coordinate system;
performing coordinate conversion on the ultrasonic image data of the rectangular coordinate system to convert the ultrasonic image data of the rectangular coordinate system into ultrasonic image data of a polar coordinate system;
processing the ultrasonic image data of the polar coordinate system by a preset processing method to obtain shear wave elastic imaging for representing the elastic modulus of the object to be detected;
performing visual processing on the shear wave elasticity imaging to display the elasticity modulus of the object to be detected; wherein
The processing the ultrasonic image data of the polar coordinate system by a preset processing method comprises:
processing the ultrasonic image data of the polar coordinate system by a first processing method to obtain the displacement of any data point of the ultrasonic image data of the polar coordinate system and the shear wave propagating along the interested direction of the object to be detected; and
processing the shear wave which circularly propagates along the object to be detected by a second processing method based on the displacement of any data point to obtain a shear wave frequency dispersion curve;
wherein the processing the shear wave propagating along the circumferential direction of the object to be detected by the second processing method includes:
obtaining displacement time curves obtained by the arrival positions of the shear wave wavefront at different times based on the displacement of any data point;
performing two-dimensional Fourier transform on the displacement time curve to obtain a Fourier transform result, wherein the Fourier transform result comprises frequency values and all wave values corresponding to any frequency value;
and aiming at the interested angle, establishing a shear wave dispersion curve based on the maximum wave value corresponding to each frequency value in the interested angle.
2. The method of claim 1, wherein the coordinate transforming the ultrasound image data of the rectangular coordinate system comprises:
and carrying out spatial interpolation on the ultrasonic image data of the rectangular coordinate system to obtain the ultrasonic image data of the polar coordinate system.
3. The method of claim 2, wherein spatially interpolating ultrasound image data of the orthogonal coordinate system comprises:
determining the geometric center of the object to be detected; and
taking the geometric center as a polar coordinate origin, and respectively sampling data in the angle direction and the radius direction of the polar coordinate system according to a preset sampling rate to obtain sampling data points;
and performing spatial interpolation on the sampling data points by using the ultrasonic image data of the rectangular coordinate system to obtain the ultrasonic image data of the polar coordinate system.
4. The method of claim 1, wherein the processing the ultrasound image data of the polar coordinate system by a predetermined processing method further comprises:
and obtaining the transmission speed of the shear wave based on the displacement of any data point and the shear wave propagating along the circumferential direction of the object to be detected.
5. The method of claim 1, wherein the processing ultrasound image data of the polar coordinate system by the first processing method comprises:
carrying out spot tracking on the ultrasonic image data of the polar coordinate system to obtain radial displacement and annular displacement of any data point in the polar coordinate system; and
establishing a displacement time curve based on the radial displacement and the annular displacement;
performing two-dimensional Fourier transform on the displacement time curve to obtain a Fourier transform result, wherein different angle ranges of the Fourier transform result represent motion information of the shear wave in different directions;
and windowing the interested angle, and then carrying out inverse Fourier transform to obtain the shear wave propagating along the interested direction of the object to be detected.
6. The method of claim 5, wherein the speckle tracking of ultrasound image data of the polar coordinate system comprises:
windowing any data point in the ultrasonic image data of the polar coordinate system to obtain a data window corresponding to the data point;
and when the correlation coefficient of the data window in the ultrasonic image data of two continuous frames is maximum, determining the radial displacement and the annular displacement of the data point in the polar coordinate system.
7. The method according to claim 1, wherein said visualizing said shear wave elastography comprises:
and carrying out spatial interpolation on the shear wave elastography of the polar coordinate system to obtain visual data of the shear wave elastography.
8. A shear wave elastography device, the device comprising:
the data acquisition unit is used for acquiring sampling data of an object to be detected, and the sampling data comprises ultrasonic image data of a rectangular coordinate system;
the coordinate conversion unit is used for carrying out coordinate conversion on the ultrasonic image data of the rectangular coordinate system so as to convert the ultrasonic image data of the rectangular coordinate system into ultrasonic image data of a polar coordinate system;
the processing unit is used for processing the ultrasonic image data of the polar coordinate system through a preset processing method to obtain shear wave elastic imaging used for representing the elastic modulus of the object to be detected;
the visualization unit is used for performing visualization processing on the shear wave elastography so as to display the elastic modulus of the object to be detected; wherein,
the processing unit processes the ultrasonic image data of the polar coordinate system by a preset processing method in the following way:
processing the ultrasonic image data of the polar coordinate system by a first processing method to obtain the displacement of any data point of the ultrasonic image data of the polar coordinate system and the shear wave propagating along the interested direction of the object to be detected; and
processing the shear wave which circularly propagates along the object to be detected by a second processing method based on the displacement of any data point to obtain a shear wave frequency dispersion curve;
wherein the processing the shear wave propagating along the circumferential direction of the object to be detected by the second processing method includes:
obtaining displacement time curves obtained by the arrival positions of the shear wave wavefront at different times based on the displacement of any data point;
performing two-dimensional Fourier transform on the displacement time curve to obtain a Fourier transform result, wherein the Fourier transform result comprises frequency values and all wave values corresponding to any frequency value;
and aiming at the interested angle, establishing a shear wave dispersion curve based on the maximum wave value corresponding to each frequency value in the interested angle.
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107440740B (en) 2017-07-21 2021-06-25 无锡海斯凯尔医学技术有限公司 Method and device for determining viscoelasticity of medium
CN107577642B (en) * 2017-08-25 2020-06-23 深圳中科乐普医疗技术有限公司 A method for realizing shear wave direction filtering and medical ultrasonic equipment
CN107970043B (en) * 2017-12-28 2021-01-19 深圳开立生物医疗科技股份有限公司 Shear wave detection method and device
CN109567872B (en) * 2018-11-05 2020-04-24 清华大学 Blood vessel guided wave elastic imaging method and system based on machine learning
NL2023174B1 (en) * 2019-05-21 2020-12-01 Beugen J Van Beheer Bv Apparatus and method for pipeline inspection
CN110420036B (en) * 2019-08-01 2021-03-09 无锡海斯凯尔医学技术有限公司 Multi-type probe compatible data processing method and device and readable storage medium
CN110897656B (en) * 2019-12-12 2022-06-21 首都医科大学附属北京友谊医院 Ultrasonic shear wave elasticity measuring method and device
CN111449681B (en) * 2020-04-08 2023-09-08 深圳开立生物医疗科技股份有限公司 Shear wave imaging method, device, equipment and readable storage medium
WO2021212494A1 (en) * 2020-04-24 2021-10-28 深圳迈瑞生物医疗电子股份有限公司 Viscosity and elasticity measurement method and ultrasonic measurement system
CN111671464A (en) * 2020-06-19 2020-09-18 深圳开立生物医疗科技股份有限公司 Image marking method, device, equipment and readable storage medium

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102283679A (en) * 2011-08-04 2011-12-21 中国科学院深圳先进技术研究院 Ultrasonic imaging system for elasticity measurement and method for measuring elasticity of biological tissue
CN102805616A (en) * 2011-06-02 2012-12-05 曹铁生 Novel index for testing partial elasticity of artery
CN102961166A (en) * 2011-08-31 2013-03-13 通用电气公司 Method for detecting and tracing needle
CN104398271A (en) * 2014-11-14 2015-03-11 西安交通大学 Method using three-dimensional mechanics and tissue specific imaging of blood vessels and plaques for detection

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9044192B2 (en) * 2008-04-07 2015-06-02 Mayo Foundation For Medical Education And Research System and method for non-invasively measuring tissue viscoelasticity using surface waves
US10624612B2 (en) * 2014-06-05 2020-04-21 Chikayoshi Sumi Beamforming method, measurement and imaging instruments, and communication instruments

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102805616A (en) * 2011-06-02 2012-12-05 曹铁生 Novel index for testing partial elasticity of artery
CN102283679A (en) * 2011-08-04 2011-12-21 中国科学院深圳先进技术研究院 Ultrasonic imaging system for elasticity measurement and method for measuring elasticity of biological tissue
CN102961166A (en) * 2011-08-31 2013-03-13 通用电气公司 Method for detecting and tracing needle
CN104398271A (en) * 2014-11-14 2015-03-11 西安交通大学 Method using three-dimensional mechanics and tissue specific imaging of blood vessels and plaques for detection

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