CN106600579A - Magnetic resonance image wave spectrum analysis method and device - Google Patents
Magnetic resonance image wave spectrum analysis method and device Download PDFInfo
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- CN106600579A CN106600579A CN201611076526.3A CN201611076526A CN106600579A CN 106600579 A CN106600579 A CN 106600579A CN 201611076526 A CN201611076526 A CN 201611076526A CN 106600579 A CN106600579 A CN 106600579A
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Abstract
The invention provides a magnetic resonance image wave spectrum analysis method and device. The method comprises the following steps: magnetic resonance image data is obtained, a voxel scope of magnetic resonance wave spectrum analysis and metabolite to be displayed are obtained, concentration of the metabolite corresponding to the voxels in the voxel scope is calculated based on the magnetic resonance image data and the obtained metabolite, and the concentration of the metabolite is displayed in a visualized manner as a magnetic resonance wave spectrum analysis result; a method for obtaining the voxel scope of magnetic resonance wave spectrum analysis comprises the following steps: an operation type is obtained; at least two operation modes are activated based on the operation type; the operation modes are obtained, voxel obtaining modes corresponding to the operation modes are activated, the voxels are obtained, and the voxel scope is obtained according to the operation type and the obtained voxels. Via the magnetic resonance image wave spectrum analysis method and device disclosed in a technical solution of the invention, an interaction process during voxel selection is improved, and user experience is improved.
Description
Technical field
The present invention relates to field of medical images, more particularly to magnetic resonance image (MRI) Spectrum Analysis.
Background technology
MRS (MRS, Magnetic Resonance Spectroscopy) be using electromagnetic induction phenomenon and
The method that chemical shift effect carries out specific atoms nuclei and compound quantitative analyses is that one kind developed in recent years is non-invades
Entering property determines the technology of important compound metabolism.Certain group is detected by determining the concentration of certain compound or complex metabolism thing
The exception knitted is the diagnostic means that user commonly uses, but tissue profile is possibly irregular, or has Various Tissues to need
Notification analysis are wanted to observe.
At present in the poster processing soft of Spectrum Analysis, selection of the user to voxel, but the interaction that voxel is selected can be met
Mode is that complicated, flow process is unintelligible, the selection of multi-voxel proton only support it is single choose, or even discontinuous voxel can not be entered
The unified analysis of row, have impact on the diagnosis experience of user, reduces the diagnosis efficiency of user.
The content of the invention
The problem to be solved in the present invention is to provide a kind of MRS method for displaying image and Medical Image Processing
Device, the interaction for solving existing magnetic resonance image (MRI) Spectrum Analysis are complicated, dumb, affect the problem of Consumer's Experience.
To solve the above problems, the invention provides a kind of magnetic resonance image (MRI) analysis method by use of spectrum, including：Obtain magnetic resonance
View data, obtains the voxel scope and metabolite to be shown of MRS；Based on the magnetic resonance image (MRI) number
According to this and the metabolite that obtains, calculate the concentration of the voxel correspondence metabolite in the range of the voxel；By the metabolism
The concentration visualization of thing shows, used as MRS result；The voxel scope bag for obtaining MRS
Include：Obtain action type；At least two modes of operation are activated simultaneously based on the action type；Mode of operation is obtained, according to institute
The voxel for stating mode of operation activation corresponded manner is obtained；Obtain voxel；According to the action type and the voxel of the acquisition
It is calculated voxel scope.
Preferably, the voxel according to action type and the acquisition is calculated voxel scope and includes：Obtain just
Initial body element scope；Based on the initial voxel scope, the corresponding calculating side of the action type is performed to the voxel of the acquisition
Formula obtains final voxel scope, used as calculated voxel scope.
Preferably, the action type includes any one following：Newly-increased voxel, deletion voxel or change voxel.
Preferably, the mode of operation includes any one following：Point selection, rectangular selection, circular selection or free
Pen is selected.
To solve the above problems, present invention also offers a kind of magnetic resonance image (MRI) Spectrum Analysis device, including：Memorizer,
Can be by the instruction of computing device for storage；Processor, for execute instruction, the instruction includes：Obtain Magnetic Resonance Spectrum
The voxel scope and metabolite to be shown of analysis；Based on the magnetic resonance image data and the metabolite of acquisition,
Calculate the concentration of the voxel correspondence metabolite in the range of the voxel；The concentration visualization of the metabolite is shown, as
MRS result；The voxel scope for obtaining MRS includes：Obtain action type；Based on described
Action type activates at least two modes of operation simultaneously；Mode of operation is obtained, and corresponded manner is activated according to the mode of operation
Voxel is obtained；Obtain voxel；Voxel scope is calculated according to the voxel of the action type and the acquisition.
Preferably, the voxel scope includes monomer element or including multi-voxel proton.
Preferably, also including display interface, for the voxel scope is shown in real time.
Preferably, the display interface includes voxel selection region, and the voxel selection region is for the voxel model
Enclose and selected.
Preferably, the voxel selection region is additionally operable to select the action type.
Preferably, the display interface also includes control panel region, and the control panel region is for the operation
Mode is selected.
Compared with prior art, technical scheme provides a kind of magnetic resonance image (MRI) analysis method by use of spectrum and dress
Put, improve the interaction when voxel is selected, improve Consumer's Experience.
Description of the drawings
Fig. 1 is the structural representation of the computer equipment of some embodiments of the invention；
Fig. 2 is the magnetic resonance image (MRI) analysis method by use of spectrum flow chart of some embodiments of the invention；
Fig. 3 is the display interface schematic diagram of some embodiments of the invention；
Fig. 4 is the acquisition voxel areas method flow diagram of some embodiments of the invention；
Fig. 5 is the interface schematic diagram that the mode of operation of some embodiments of the invention is selected；
Fig. 6 a-6c are that the voxel of some embodiments of the invention obtains schematic diagram.
Specific embodiment
It is understandable to enable the above objects, features and advantages of the present invention to become apparent from, below in conjunction with the accompanying drawings to the present invention
Specific embodiment be described in detail.Elaborate detail in order to fully understand the present invention in the following description.But
It is that the present invention can be implemented different from alternate manner described here with various, those skilled in the art can be without prejudice to this
Similar popularization is done in the case of invention intension.Therefore the present invention is not limited by following public specific embodiment.
As shown in the application and claims, unless context clearly points out exceptional situation, " one ", " one ", " one
The word such as kind " and/or " being somebody's turn to do " not refers in particular to odd number, may also comprise plural number.It is, in general, that term " including " only points out bag with "comprising"
Include the step of clearly identifying and element, and these steps and element do not constitute one it is exclusive enumerate, method or equipment
It is likely to comprising the step of other or element.
Flow chart used herein is used for illustrating the operation according to performed by the system of embodiments herein.Should
Be understood by, before or operation below not necessarily in order accurately carrying out.Conversely, according to inverted order or while can process
Various steps.It is also possible to during other operations are added to these, or a certain step or number step behaviour are removed from these processes
Make.
Fig. 1 is the structural representation of the computer equipment of some embodiments of the invention.Computer 100 can be used for realizing
The ad hoc approach disclosed in implementing some embodiments of the invention and device.Specific device in the present embodiment utilizes functional block diagram exhibition
A hardware platform comprising display module is shown.In certain embodiments, computer 100 can be by its hardware device, soft
Part program, firmware and combinations thereof are realizing being embodied as some embodiments of the invention.In certain embodiments, calculate
Machine 100 can be the computer of a general purpose, or a computer for having specific purpose.
As shown in figure 1, computer 100 can include internal communication bus 101, processor (processor) 102 is read-only
Memorizer (ROM) 103, random access memory (RAM) 104, COM1 105, input output assembly 106, hard disk 107, with
And user interface 108.Internal communication bus 101 can realize the data communication of 100 inter-module of computer.Processor 102 can be with
Judged and sent prompting.In certain embodiments, processor 102 can be made up of one or more processors.Communication ends
Mouth 105 can realize computer 100 with miscellaneous part (not shown) for example：External equipment, image capture device, data
Enter row data communication between storehouse, external storage and image processing workstations etc..In certain embodiments, computer 100 can be with
Sent from network by COM1 105 and receive information and data.Input output assembly 106 support computer 100 and other
Input/output data stream between part.User interface 108 can realize the interaction between computer 100 and user and information
Exchange.Computer 100 can also include the program storage unit and data storage element of multi-form, such as hard disk 107, only
Read memorizer (ROM) 103, random access memory (RAM) 104, can store computer disposal and/or that communication is used is various
Data file, and the possible programmed instruction performed by processor 102.
Fig. 2 is the MRS method for displaying image flow chart of some embodiments of the invention, below in conjunction with Fig. 3's
Display interface schematic diagram is illustrated.Display interface 300 is shown that by user interface 108 user can be according to input/output
Component 106 is controlled to interface elements such as the text box in display interface 300, control, image, words, for example, carry out data
Input, click/mobile virtual button, drag draw runner, movement/rotation/zoomed image etc. and operate.
Fig. 3 is the display interface schematic diagram of MRS application, and MRS application can be combined
One or more voxels in magnetic resonance image (MRI) are carried out Spectrum Analysis by magnetic resonance image (MRI), for judging one or more bodies
Element metabolite composition, metabolite distribution etc. information.Display interface 300 can include multiple interface zones (interface zone 310,
Interface zone 320, interface zone 330, interface zone 340, interface zone 350 and interface zone are 360).Wherein, interface zone
310 can be magnetic resonance image (MRI) sequence list region, can be used to select the magnetic resonance image (MRI) sequence of pending analysis.Interface area
Domain 320 can be control panel region, can be used to select corresponding tool to be labeled image or relevant information statistics
Deng.Interface zone 330 can be voxel selection region, for a certain/multiple magnetic resonance image (MRI) in magnetic resonance image (MRI) sequence
It is middle to select one or more voxels to be analyzed.Interface zone 340 can be metabolite scattergram viewing area, wait to have selected body
After element and metabolites kinds, the display of metabolite scattergram is carried out.Interface zone 350 can be spectrum viewing area, use
After coming according to the voxel and metabolites kinds to be analyzed for selecting, spectrum is carried out to corresponding data and is shown, spectrum can be with
It is the curve chart of each metabolite concentration change of the single or multiple voxel correspondences of statistics, the change of every kind of metabolite concentration can be with one
Bar curve is indicated.Interface zone 360 can be table statistics region, for according to the voxel and metabolites kinds for selecting
Afterwards, carry out tabular to corresponding data to show, referred to herein as corresponding data can be crest title, position, integration, ratio,
The information such as signal to noise ratio, full width at half maximum.Display interface 300 and each interface zone (interface zone 310-360) above only shows
Meaning property represent, in certain embodiments, the other forms that display interface, interface zone and corresponding interface layout can have.
Step S201, obtains magnetic resonance image data.Magnetic resonance image data can be it is interim/be permanently stored in ROM
103rd, the data in RAM 104, hard disk 107 or External memory equipment.In certain embodiments, magnetic resonance image data can be with
It is the magnetic resonance image data obtained after the scan data collected via MR imaging apparatus is rebuild.In some embodiments
In, the magnetic resonance image data for acquiring can show magnetic resonance image (MRI) number at magnetic resonance image (MRI) sequence list region 310
According to corresponding list.In certain embodiments, in the specific magnetic resonance image data in 310 pairs, magnetic resonance image (MRI) sequence list region
After being selected, magnetic resonance image data can be read, and magnetic resonance image (MRI) is shown in voxel selection region 330, now may be used
Only to show cross-sectional image, can be while showing cross-sectional profile and coronal image, or while showing cross-section
Face image, coronal image and sagittal view picture.
For the magnetic resonance image (MRI) shown in voxel selection region 330, the selection of voxel scope can be carried out by user, be selected
The voxel scope selected can be monomer element, or multi-voxel proton.In certain embodiments, when the voxel scope for selecting is many bodies
When plain, can be that continuously (as shown in Figure 3, the voxel a in voxel selection region 330 is contained continuously between each voxel
4 voxels), or discontinuous (such as voxel b or voxel c, not being connected with other voxels).
In certain embodiments, the method flow of voxel scope is obtained referring to Fig. 4.Step S401, obtains action type letter
Breath, action type information here can be newly-increased voxel, delete voxel or one or more any of change voxel
Combination.Referring to Fig. 6, action type is selected can be by carrying out correspondence choosing at the select tools region 650 of voxel selection region 330
Select.
Newly-increased voxel can, on the basis of initial voxel scope (operate before obtain voxel scope), be increased newly single
Or multiple voxels, so as to increase selected voxel, expand initial voxel scope.In certain embodiments, as shown in Figure 6 a, body
There is initial voxel scope 601 in plain selection region 330, initial voxel scope includes two voxels：Voxel d, voxel e.If behaviour
Make type to increase voxel newly, mode of operation is point selection, voxel f, body can be selected in the way of with point selection in voxel frame 600
Plain g, then now increase voxel f, voxel g on the basis of initial voxel scope newly, the final voxel scope of form 602.In some realities
Apply in example, newly-increased voxel scope can be had with the initial voxel scope for existing before and necessarily overlap, in this case final
Analysis when, overlapping region can only be calculated only once.
It can, on the basis of initial voxel scope (operate before obtain voxel scope), delete single to delete voxel
Or multiple voxels, so as to reduce selected voxel, reduce initial voxel scope.In certain embodiments, as shown in Figure 6 b, body
There is initial voxel scope 603 in plain chosen area 330, initial ancient wine scope is only made up of voxel h.If action type is deletion
Voxel, mode of operation are circular selection, can select voxel i, then now first in voxel frame 600 in the way of with circular selection
Delete voxel i on the basis of initial body element scope, and the final voxel scope of form 604 (due to when voxel is selected, no matter mode of operation
Be which kind of type, can only select one or more voxels for being covered by opereating specification completely, therefore finally work be selected by circular
The voxel i that work is chosen is still one or more rectangle voxels).
Change voxel can be on the basis of initial voxel scope (operate before obtain voxel scope), to single or
Multiple voxels are modified, and for example initial voxel scope (operating the voxel scope for obtaining before) is by rectangular selection instrument, circle
Shape select tools or free select tools select what is obtained, and change voxel can be in initial voxel scope (circular scope, square
Shape scope or arbitrary shape) on the basis of be modified.In certain embodiments, change can be change initial voxel scope
Interior one/multiple voxels, for example, change diameter, the position of the circular voxel areas obtained by circular selection in initial voxel region
Put.In certain embodiments, as fig. 6 c, there is initial voxel scope 605, initial ancient wine in voxel chosen area 330
Scope is only made up of voxel j.If action type is change voxel, the voxel to be changed in the range of initial voxel is according to circle
What selection was obtained, voxel j can be moved to other positions in voxel frame 600, form final voxel scope 606, Huo Zhegai
Become the diameter of voxel j, form final voxel scope 607.
Step S402, after acquisition completes action type information, activation manipulation way choice, mode of operation can be to body
The selection mode of element, shown in mode of operation selection interface accompanying drawing 5.Referring to Fig. 5, the selection of mode of operation can be in control panel district
Domain 320 is carried out, and can be specifically, in mode of operation selection region 500, to be respectively equipped with correspondence button：Point selection 501, rectangle is selected
Select 502, circular selection (not shown), free pen and select 503.In certain embodiments, step S402 simultaneously activate to
Few two kinds of modes of operation, so as to provide more flexible operation scheme.Step S403, obtains mode of operation information, mode of operation
Information can be one or more the combination in any that point selection, rectangular selection, circular selection or free pen are selected.Click
Selecting can be that the voxel inframe of magnetic resonance image (MRI) in voxel selection region 330 selects single voxel every time in dots.Square
Shape select can be 330 magnetic resonance image (MRI) of voxel selection region voxel inframe with the formal character for drawing rectangle it is single/it is multiple
Voxel.It is circular to select be in the voxel inframe of 330 magnetic resonance image (MRI) of the voxel selection region shape oval to draw circle or picture
Formula selects single/multiple voxel.Free pen select can be 330 magnetic resonance image (MRI) of voxel selection region voxel inframe with from
By draw shape formal character it is single/multiple voxels.Now according to specifically chosen mode of operation, activation correspondence obtains voxel
When method.If for example mode of operation information is point selection, providing point selection instrument carries out voxel acquisition.If mode of operation is believed
Breath is rectangular selection, then providing rectangular selection instrument carries out voxel acquisition.If mode of operation information is circular selection, circle is provided
Shape select tools carry out voxel acquisition.If mode of operation information is free pen selecting, providing free drawing tool carries out body
Element is obtained.
Step S404, user carry out voxel selection according to the voxel select tools for providing, and obtain selected voxel institute right
The voxel information answered.Step S405, is calculated voxel scope according to action type information and voxel information, for example, operate class
Type information is newly-increased voxel, and voxel information is a certain piece of voxel areas, then increase the voxel areas newly, if there is initial voxel scope
Then the voxel areas are increased newly on initial voxel scope be defined as voxel scope, should if it there is no initial voxel scope
Voxel areas are defined as voxel scope.
In certain embodiments, voxel scope with operation can be in reality at the voxel selection region 330 of display interface 300
When show.
After acquiring voxel scope, metabolites kinds information can be further obtained.User can be selected in metabolite
Metabolites kinds information to be shown is selected in control.Metabolites kinds can be NAA, NAA 3, Cr, Cho, Cr2, Lac,
At least one or more of combination of Lip, Glx m1, Glx m2, Glx dd, NAA dd1, NAA dd2.In some embodiments
In, a metabolites kinds information can be only selected, for example, selects Cr.In some embodiments, two can be selected simultaneously
Metabolites kinds information, for example, select Cr, Cho simultaneously.In certain embodiments, three metabolites kinds letters can be selected simultaneously
Breath, for example, select Cr, Cho, NAA 3 simultaneously.In certain embodiments, four metabolites kinds information, example can be selected simultaneously
As selected NAA, Cr, Cho, Cr2 simultaneously.In certain embodiments, can also select simultaneously more than four metabolites kinds information.
Step S202, based on the metabolites kinds information of magnetic resonance image data and acquisition, calculates body in the range of voxel
The concentration of each metabolites kinds of element correspondence.In certain embodiments, the MR data of each voxel in the range of voxel can be entered
Line frequency analysis of spectrum, finds the corresponding corresponding frequency spectrum of metabolites kinds being selected and is calculated respective concentration, and this process is
Technology known to those skilled in the art.For example for voxel a, it is Cr and Cho, voxel a if necessary to the metabolites kinds of analysis
4 voxels of correspondence, can carry out spectrum analyses according to the corresponding MR data of each voxel and be calculated correspondence metabolism respectively
The data of thing Cr and Cho, are further calculated the concentration of the Cr and Cho of corresponding each voxel.In certain embodiments, voxel
A its correspondence 4 voxels, it is also possible to being combined the MR data of 4 voxels carries out spectrum analyses, finally obtains complete body
The concentration of the corresponding each metabolite (such as Cr and Cho) of plain a, i.e., be only calculated a data.
Step S203, the concentration of each metabolites kinds is visualized, and specific visual means can be in display interface
Metabolite scattergram is shown, can be each metabolites kinds spectrum, the product that the single/multiple voxels of correspondence are shown in display interface
Component is shown with tabular form, and visual result is used as MRS result.
Metabolite scattergram is used for representing each voxel of correspondence, the distribution situation of one or more metabolite concentrations.Metabolite
Scattergram is generally indicated with the form of pcolor, and in display interface, pcolor is covered in and represents that the magnetic of anatomical structure is common
Shake on image, or pcolor is covered in the magnetic resonance image (MRI) for representing functional structure.In certain embodiments, when simultaneously
When showing metabolite scattergram and magnetic resonance feature/anatomical structural images, the fusion that can adjust two kinds of images shows ratio
Example.In certain embodiments, calculate metabolite scattergram to be shown at metabolite scattergram viewing area 340, and
And the number of the metabolite scattergram shown at metabolite scattergram viewing area 340 and the metabolites kinds number phase for selecting
Together.In certain embodiments, if step S201 obtain four metabolites kinds (for example at the same have selected NAA, Cr, Cho,
Cr2), then four metabolite scattergrams are shown simultaneously at metabolite scattergram viewing area 340, wherein every metabolite distribution
Figure one metabolites kinds of correspondence.At metabolite scattergram viewing area 340, can be with for the layout of each metabolite scattergram
It is the distribution form of 2*2, it would however also be possible to employ the distribution form of other distribution forms, such as 1*4 or 4*1.
Metabolites kinds spectrum can represent each metabolite concentration change.Integrogram can represent selection region intracellular metabolite
Thing concentration accumulation situation within a certain period of time.Tabular form can represent the related title of metabolite concentration, peak value, position
Put, integrate, the statistical information such as ratio, signal to noise ratio, full width at half maximum.
Technical scheme provides a kind of magnetic resonance image (MRI) analysis method by use of spectrum and device, including：Memorizer, uses
Can be by the instruction of computing device in storage；Processor, for execute instruction, the instruction includes：Obtain Magnetic Resonance Spectrum point
The voxel scope and metabolite to be shown of analysis；Based on the magnetic resonance image data and the metabolite of acquisition, count
Calculate the concentration of the voxel correspondence metabolite in the range of the voxel；The concentration visualization of the metabolite is shown, as magnetic
Resonance Spectrum Analysis result；The voxel scope for obtaining MRS includes：Obtain action type；Based on the behaviour
Make type while activating at least two modes of operation；Mode of operation is obtained, and the body of corresponded manner is activated according to the mode of operation
Element is obtained；Obtain voxel；Voxel scope is calculated according to the voxel of the action type and the acquisition.
In certain embodiments, voxel scope includes monomer element or including multi-voxel proton.
In certain embodiments, also including display interface, for the voxel scope is shown in real time.
In certain embodiments, display interface includes voxel selection region, and the voxel selection region is for the body
Plain scope is selected.
In certain embodiments, voxel selection region is additionally operable to select the action type.
In certain embodiments, display interface also includes control panel region, and the control panel region is for described
Mode of operation is selected.
Technical scheme improves the interaction when voxel is selected, and improves Consumer's Experience.
Although the present invention is disclosed as above with preferred embodiment, which is not for limiting the present invention, any this area
Technical staff without departing from the spirit and scope of the present invention, may be by the methods and techniques content of the disclosure above to this
Bright technical scheme makes possible variation and modification, therefore, every content without departing from technical solution of the present invention, according to the present invention
Technical spirit any simple modification, equivalent variations and modification that above example is made, belong to technical solution of the present invention
Protection domain.
Meanwhile, the application describes embodiments herein using particular words.Such as " one embodiment ", " one implements
Example ", and/or " some embodiments " mean a certain feature related at least one embodiment of the application, structure or feature.Cause
This, it should be highlighted that and it is noted that " embodiment " or " enforcement that are referred in diverse location twice or repeatedly in this specification
Example " or " alternate embodiment " are not necessarily meant to refer to same embodiment.Additionally, in one or more embodiments of the application
Some features, structure or feature can carry out appropriate combination.
Additionally, it will be understood by those skilled in the art that each side of the application can pass through some with patentability
Species or situation are illustrated and described, including the combination of any new and useful operation, machine, product or material or right
Their any new and useful improvement.Correspondingly, the various aspects of the application can completely by hardware perform, can be complete
Performed, can also be performed by combination of hardware by software (including firmware, resident software, microcode etc.).Hardware above is soft
Part is referred to alternatively as " data block ", " module ", " submodule ", " engine ", " unit ", " subelement ", " component " or " system ".This
Outward, each side of the application may show as the computer product in one or more computer-readable mediums, the product
Encode including computer-readable program.
Computer-readable signal media may include a propagation data signal for being contained within computer program code, for example
In base band or as a part for carrier wave.The transmitting signal may have a many forms, including electromagnetic form, light form etc.
Deng, or suitable combining form.Computer-readable signal media can be any meter in addition to computer-readable recording medium
Calculation machine computer-readable recording medium, the medium can by being connected to instruction execution system, device or an equipment realizing communicating, propagate or
Transmit the program for using.Program coding in computer-readable signal media can be carried out by any suitable medium
Propagate, including the combination of radio, cable, fiber optic cables, radiofrequency signal or similar mediums or any of above medium.
Computer program code needed for the operation of the application each several part can use any one or more programming language,
Including Object-Oriented Programming Language such as Java, Scala, Smalltalk, Eiffel, JADE, Emerald, C++, C#, VB.NET,
Python etc., conventional procedural programming language for example C language, Visual Basic, Fortran 2003, Perl, COBOL 2002,
PHP, ABAP, dynamic programming language such as Python, Ruby and Groovy, or other programming languages etc..The program coding can be with complete
Full operation on the user computer, or run as independent software kit on the user computer, or part in subscriber computer
Upper operation part in remote computer operation, or run completely on remote computer or server.In the latter cases, remotely
Computer can be connected with subscriber computer by any latticed form, such as LAN (LAN) or wide area network (WAN), or even
Outer computer (such as by the Internet) is connected to, or in cloud computing environment, or serviced using such as software as service
(SaaS)。
It is additionally, except clearly stating in non-claimed, the order of herein described processing element and sequence, number-letter
Using, or other titles use, be not intended to limit the order of the application flow process and method.Although by each in above-mentioned disclosure
Kind of example discusses some it is now recognized that useful inventive embodiments, but it is to be understood that, such details only plays explanation
Purpose, appended claims are not limited in the embodiment for disclosing, conversely, claim is intended to, and covering is all to meet the application
The amendment of embodiment spirit and scope and equivalent combinations.For example, although system component described above can be set by hardware
It is standby to realize, but only can also be achieved by the solution of software, pacify such as on existing server or mobile device
The described system of dress.
In the same manner, it is noted that in order to simplify herein disclosed statement, it is real to one or more inventions so as to help
Apply the understanding of example, above to the description of the embodiment of the present application in, sometimes by various features merger to one embodiment, accompanying drawing or
In descriptions thereof.But, this disclosure method is not meant to carry in the aspect ratio claim required for the application object
And feature it is many.In fact, the feature of embodiment will be less than whole features of the single embodiment of above-mentioned disclosure.
Description composition, the numeral of number of attributes used in some embodiments, it should be appreciated that such for embodiment
The numeral of description, in some instances using qualifier " about ", " approximate " or " generally " modifying.Unless said in addition
Bright, " about ", " approximate " or " generally " shows that the numeral allows ± 20% change.Correspondingly, in some embodiments
In, the numerical parameter used in description and claims is approximation, approximation feature according to needed for separate embodiment
Can change.In certain embodiments, numerical parameter is considered as the significant digit for specifying and is retained using general digit
Method.Although the Numerical Range and parameter in the application some embodiments for confirming its scope range is approximation, concrete real
Apply in example, being set in for such numerical value is reported as precisely as possible in feasible region.
Each patent, patent application, patent application publication thing and the other materials quoted for the application, such as article, book
Nationality, description, publication, document etc., are incorporated herein entire contents as reference hereby.It is inconsistent with teachings herein
Or except producing the application history file of conflict, to the conditional file of the application claim widest scope (currently or afterwards
Be additional in the application) also except.If it should be noted that the description, definition, and/or art in the application attaching material
The use of language with it is herein described it is interior have it is inconsistent or where conflicting, with making for the description of the present application, definition and/or term
With being defined.
Finally, it will be understood that embodiment described herein is only to illustrate the principle of the embodiment of the present application.Other
Deformation be likely to belong to scope of the present application.Unrestricted accordingly, as example, the alternative configuration of the embodiment of the present application is visual
It is consistent with teachings of the present application.Correspondingly, embodiments herein is not limited only to the enforcement that the application is clearly introduced and described
Example.
Claims (10)
1. a kind of magnetic resonance image (MRI) analysis method by use of spectrum, it is characterised in that include：
Magnetic resonance image data is obtained, the voxel scope and metabolite to be shown of MRS is obtained；
Based on the magnetic resonance image data and the metabolite of acquisition, voxel correspondence in the range of the voxel is calculated described
The concentration of metabolite；
The concentration visualization of the metabolite is shown, as MRS result；
The voxel scope for obtaining MRS includes：Obtain action type；Swashed based on the action type simultaneously
At least two modes of operation living；Mode of operation is obtained, and the voxel for corresponded manner being activated according to the mode of operation is obtained；Obtain body
Element；Voxel scope is calculated according to the voxel of the action type and the acquisition.
2. method according to claim 1, it is characterised in that the voxel meter according to action type and the acquisition
Calculation obtains voxel scope to be included：
Obtain initial voxel scope；
Based on the initial voxel scope, the corresponding calculation of the voxel execution action type of the acquisition is obtained most
Whole voxel scope, as calculated voxel scope.
3. method according to claim 1, it is characterised in that the action type includes any one following：It is newly-increased
Voxel, deletion voxel or change voxel.
4. method according to claim 1, it is characterised in that the mode of operation includes any one following：Click
Select, rectangular selection, circle are selected or free pen is selected.
5. a kind of magnetic resonance image (MRI) Spectrum Analysis device, it is characterised in that include：
Memorizer, can be by the instruction of computing device for storage；
Processor, for execute instruction, the instruction includes：
Magnetic resonance image data is obtained, the voxel scope and metabolite to be shown of MRS is obtained；
Based on the magnetic resonance image data and the metabolite of acquisition, voxel correspondence in the range of the voxel is calculated described
The concentration of metabolite；
The concentration visualization of the metabolite is shown, as MRS result；
The voxel scope for obtaining MRS includes：Obtain action type；Swashed based on the action type simultaneously
At least two modes of operation living；Mode of operation is obtained, and the voxel for corresponded manner being activated according to the mode of operation is obtained；Obtain body
Element；Voxel scope is calculated according to the voxel of the action type and the acquisition.
6. device according to claim 5, it is characterised in that the voxel scope includes monomer element or including multi-voxel proton.
7. device according to claim 5, it is characterised in that also including display interface, for by the voxel scope reality
When show.
8. device according to claim 5, it is characterised in that the display interface includes voxel selection region, the body
Plain selection region is for selecting to the voxel scope.
9. device according to claim 8, it is characterised in that the voxel selection region is additionally operable to the action type
Selected.
10. device according to claim 8, it is characterised in that the display interface also includes control panel region, described
Control panel region is for selecting to the mode of operation.
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