CN106516308A - Full-automatic tail filling steric filling and sealing machine - Google Patents

Abstract

The invention discloses a full-automatic tail irrigation aseptic filling and sealing machine, which comprises an aseptic isolation cover provided with a liquid mixing feed port and a filling and sealing assembly line installed in the aseptic isolation cover. Bag device, edge trimming device, filling device, sealing device and bag unloading device, also includes a conveying device for the relative movement of the soft bag and the filling and sealing line. The filling and sealing line obtains sterile soft bags for filling operations. Since the soft bags are kept sterile and the filling process is always in a sterile environment, it is avoided to sterilize the soft bags containing the liquid after filling The operation makes some liquids that are not suitable for high-temperature sterilization avoid the property change caused by high temperature, and ensures the effective medical effect of the final product. At the same time, the device avoids the problem that it is difficult to detect and sterilize the produced soft bags before filling, improves the work efficiency of filling liquid, and has higher safety.

Description

A fully automatic tail irrigation aseptic filling and sealing machine

technical field

The invention relates to the technical field of medical equipment, and more specifically relates to a fully automatic tail irrigation aseptic filling and sealing machine.

Background technique

The medical solution for infusion is usually filled in vials or soft bags, which is convenient for subsequent medical personnel to use on patients.

The medical solution and the soft bag after filling should be sterile to avoid adverse reactions after use. In the traditional filling process, the production of soft bags and the filling and filling liquid are integrated. After the soft bags are produced, they are directly filled with liquid, then sterilized, and finally the finished soft bags filled with liquid are output. In the above-mentioned processing and production process, the dosing solution is sterilized at high temperature along with the soft bag produced, but some of the liquid medicine is easily changed under high temperature conditions, which affects the quality of the final medicine.

In addition, the integrated design of bag making and filling makes it impossible to inspect the soft bags made before filling. If the empty bags themselves contain bacteria, it will also affect the qualified rate of the final product.

To sum up, how to effectively solve the problem that the properties of drugs are prone to change after high-temperature sterilization of soft infusion bags is an urgent problem for those skilled in the art.

Contents of the invention

In view of this, the object of the present invention is to provide a fully automatic tail irrigation aseptic filling and sealing machine. The problem of change.

In order to achieve the above object, the present invention provides the following technical solutions:

A full-automatic aseptic filling and sealing machine for tail irrigation, comprising a sterile isolation cover provided with a liquid feeding port and a filling and sealing assembly line installed in the sterile isolation cover, the filling and sealing assembly line includes a bagging device, a cutting Side device, filling device, sealing device and bag-down device, as well as a conveying device for the relative movement of the soft bag and the filling and sealing line.

Preferably, in the above-mentioned fully automatic tail irrigation aseptic filling and sealing machine, the conveying device includes a circular conveying assembly, and the conveying device is connected to a power distribution cabinet.

Preferably, in the above-mentioned fully automatic tail irrigation aseptic filling and sealing machine, the bag loading device includes a bag loading jig for clamping the soft bag, and a filling jig for clamping the soft bag is provided on the circular transfer assembly.

Preferably, in the above-mentioned fully automatic aseptic filling and sealing machine for tail irrigation, the trimming device includes a pressing assembly for pressing the soft bag and a cutting device for cutting off the bottom sealing area of the soft bag, and also includes a cutting device for removing Waste side take-up device.

Preferably, in the above-mentioned fully automatic tail filling aseptic filling and sealing machine, the filling device includes a bag pressing assembly for compressing the soft bag and a pressure assembly for filling the filling liquid, and also includes a filling machine for the flow-through dosing pipeline.

Preferably, in the above-mentioned fully automatic tail-fill aseptic filling and sealing machine, the sealing device includes a sealing mold for welding the opening of the soft bag.

Preferably, the above-mentioned fully automatic tail filling aseptic filling and sealing machine further includes a cleaning device located between the bag loading device and the trimming device, and the cleaning device includes an ion wind blowing component, an air collecting component and a return air pipeline.

Preferably, the above-mentioned fully automatic tail-fill aseptic filling and sealing machine further includes a punching device located between the sealing device and the lower bag device, and the punching device is used to open a hanging hole at the tail of the soft bag.

Preferably, in the above-mentioned fully automatic tail irrigation aseptic filling and sealing machine, the aseptic isolation cover is equipped with a dust particle detection device, a planktonic bacteria monitoring device and a temperature and humidity monitoring device.

The fully automatic tail irrigation aseptic filling and sealing machine provided by the present invention includes a sterile isolation cover provided with a liquid feeding inlet and a filling and sealing assembly line installed in the sterile isolation cover, and the filling and sealing assembly line includes bagging devices arranged in sequence , trimming device, filling device, sealing device and bag-down device, and also includes a conveying device for the relative movement of the soft bag and the filling and sealing line.

When using the full-automatic tail-filling aseptic filling and sealing machine provided by the present invention, the filling and sealing line obtains aseptic soft bags for filling operation, including clamping the soft bag tail upwards to the filling and sealing line and starting to transfer, and then cutting Open the sealing area at the end of the soft bag and fill the filling liquid under aseptic conditions, and finally seal the opening at the end of the hose and unload the filled soft bag from the filling and sealing line for subsequent use. Since the soft bag is kept aseptic and the filling process is always in a sterile environment, it avoids the operation of sterilizing the soft bag containing the liquid after filling, which makes some liquids not suitable for high temperature sterilization The property change caused by high temperature is avoided, and the effective medical effect of the final product is guaranteed.

At the same time, the fully automatic tail filling aseptic filling and sealing machine provided by the present invention avoids the problem that it is difficult to detect and sterilize the produced soft bags before filling, improves the working efficiency of filling liquid, and has higher safety .

Description of drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings that need to be used in the description of the embodiments or the prior art. Obviously, the accompanying drawings in the following description are only These are some embodiments of the present invention. Those skilled in the art can also obtain other drawings based on these drawings without creative work.

Fig. 1 is the structural representation of the automatic tail irrigation aseptic filling and sealing machine provided by the embodiment of the present invention;

Fig. 2 is a schematic structural view of the potting assembly line provided by the embodiment of the present invention;

Fig. 3 is a structural schematic diagram of a bagging device provided by an embodiment of the present invention;

Fig. 4 is a schematic structural diagram of an edge trimming device provided by an embodiment of the present invention;

5 is a schematic structural view of a filling device provided by an embodiment of the present invention;

Fig. 6 is a schematic structural view of the bag lowering device provided by the embodiment of the present invention;

Fig. 7 is a schematic structural diagram of a cleaning device provided by an embodiment of the present invention.

The markings in the attached drawings are as follows:

Sterile isolation cover 1, liquid preparation inlet 11, bag loading device 2, bag loading fixture 21, edge trimming device 3, pressing assembly 31, cutting device 32, waste edge removing device 33, filling device 4, bag pressing Component 41, pressure component 42, filling pipeline 43, lower bag device 5, cleaning device 6, ion wind blowing component 61, gas collection component 62, return air pipeline 63, circular transfer component 7, potting fixture 71, Power distribution cabinet 8, soft bag 9.

detailed description

The embodiment of the present invention discloses a fully automatic tail irrigation aseptic filling and sealing machine, so as to avoid the change of the properties of the dosing liquid caused by high-temperature sterilization after the filling and filling liquid is completed, and improve the safety and work efficiency of the filling and filling process.

The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

Please refer to FIG. 1 , which is a schematic structural diagram of a fully automatic tail irrigation aseptic filling and sealing machine provided by an embodiment of the present invention.

Embodiments of the present invention provide a fully automatic tail irrigation aseptic filling and sealing machine, comprising an aseptic isolation cover 1 provided with a liquid feeding inlet 11 and a filling and sealing assembly line installed in the aseptic isolation cover 1, the potting The assembly line includes a bag-up device 2, a trimming device 3, a filling device 4, a sealing device and a bag-down device 5 arranged in sequence, and also includes a conveying device for the relative movement of the soft bag 9 and the filling and sealing line. The above-mentioned relative movement can preferably be that the soft bag 9 moves while each device on the potting line does not move, which is convenient and efficient to process. Of course, the position of the soft bag 9 can be fixed and each device passes through each soft bag 9 in sequence and performs corresponding operations.

When using the full-automatic tail-irrigation aseptic filling and sealing machine provided by the above-mentioned embodiment, the filling and sealing line obtains the aseptic soft bag 9 for filling operation, including clamping the tail of the soft bag 9 to the filling and sealing line and starting to transfer , then cut the sealing area at the end of the soft bag 9 and fill it with liquid under aseptic conditions, and finally seal the opening at the end of the hose and roll off the filled soft bag 9 from the filling and sealing line for follow-up use. Since the soft bag 9 is kept in a sterile state and the filling process is always in a sterile environment, the operation of sterilizing the soft bag 9 containing the dosing solution after filling is avoided, making some of them unsuitable for high temperature sterilization The liquid preparation avoids the property change caused by high temperature and ensures the effective medical effect of the final product.

Simultaneously, the fully automatic tail filling aseptic filling and sealing machine provided by the above-mentioned embodiment avoids the problem that it is difficult to detect and sterilize the soft bag 9 produced before filling, improves the working efficiency of filling liquid, and improves the safety. higher.

Please refer to FIG. 2 . FIG. 2 is a schematic structural diagram of a potting assembly line provided by an embodiment of the present invention.

In order to optimize the use effect of the transmission device in the above embodiment, the transmission device includes a circular transmission assembly 7 , and the transmission device is connected to a power distribution cabinet 8 . The movement and processing flow of the soft bags 9 are smoother through the setting of the circular conveying device. The bag is loaded on one side, and the bag is dropped on the other side after filling, which ensures that the connection between the soft bags 9 is compact. Specifically, it can preferably be in the form of belt transmission. The power distribution cabinet 8 supplies power to the motor, controls the rotation of the motor and drives the belt to run at a certain speed or intermittently to meet processing needs.

Please refer to FIG. 3 . FIG. 3 is a schematic structural diagram of a bag loading device provided by an embodiment of the present invention.

In order to optimize the use effect of the bag-on device 2 in the above-mentioned embodiment, the bag-on device 2 includes a bag-on jig 21 for clamping the soft bag 9, and the circular transfer assembly 7 is provided with a potting jig 71 for clamping the soft bag 9 . The bag loading device 2 includes a bag loading jig 21 for clamping the soft bag 9 , and a potting jig 71 for clamping the soft bag 9 is provided on the circular transfer assembly 7 . In the actual implementation of this embodiment, the bag-loading jig 21 of the bag-loading device 2 clamps the soft bag 9 to be filled and positions the soft bag 9 to the circular transfer assembly 7 to relax, and then the potting jig 71 clamps the soft bag 9 suitable position for subsequent processing.

Please refer to FIG. 4 . FIG. 4 is a schematic structural diagram of an edge trimming device provided by an embodiment of the present invention.

In order to optimize the use effect of the trimming device 3 in the above-mentioned embodiment, the trimming device 3 includes a compression assembly 31 for compressing the soft bag 9 and a cutting device 32 for cutting off the bottom sealing area of the soft bag 9, and also includes A waste edge taking device 33 for taking away waste edges. The edge trimming device 3 cuts off the sealing area of the soft bag 9 afterbody, and reclaims the part that is cut off by getting the waste edge device 33 . The trimming device 3 can preferably be a cutter, and of course other devices that can cut the soft bag 9 can be used.

Please refer to Fig. 5 and Fig. 6, Fig. 5 is a schematic structural view of the filling device provided by the embodiment of the present invention, Fig. 6 is a schematic structural view of the lower bag device provided by the embodiment of the present invention, the lower bag device 5 includes a device for transferring The soft bag 9 that has been sealed on the device goes off the assembly line or is transferred to the clamping and running assembly of the follow-up equipment.

In order to optimize the use effect of the filling device 4 in the above embodiment, the filling device 4 includes a pressure bag assembly 41 for compressing the soft bag 9 and a pressure assembly 42 for filling the filling liquid, and also includes The filling pipeline 43. The filling pipeline 43 is connected to the external dosing chamber. Of course, the external dosing chamber should also be kept aseptic, and the whole process of passing through the dosing inlet 11 should also be aseptic. Fill in the soft bag 9.

In order to optimize the use effect of the sealing device in the above embodiment, the sealing device includes a sealing mold for welding the opening of the soft bag 9 . After the filling is completed, the soft bag 9 reaches the position of the sealing device, and the sealing molds arranged on the left and right sides are used to weld the opening of the tail of the soft bag 9 to ensure the sealing of the soft bag 9 after filling with liquid.

Please refer to FIG. 7 . FIG. 7 is a schematic structural diagram of a cleaning device provided by an embodiment of the present invention.

In order to optimize the use effect of the potting assembly line in the above embodiment, a cleaning device 6 located between the bagging device 2 and the edge trimming device 3 is also included. The cleaning device 6 includes an ion wind blowing assembly 61, an air collecting assembly 62 and a return air Line 63. The surface of the soft bag 9 is cleaned by ion wind to remove impurities and dust particles on the surface of the soft bag 9 to ensure the cleanliness of the surface of the soft bag 9, so that the soft bag 9 clamped by the bag loading device 2 can obtain a good cleaning effect. Certainly, it is also possible to directly provide the aseptic soft bag 9 to the bag-up device 2, and it is preferable to add a cleaning device 6 to clean the soft bag 9 before bag-up no matter whether it is aseptic or not.

In order to further optimize the use effect of the potting assembly line in the above embodiment, a punching device located between the sealing device and the lower bag device 5 is also included, and the punching device is used to open a hanging hole at the tail of the soft bag 9 . The soft bag 9 is punched by the preferred punching device, so that the soft bag 9 with hanging holes is convenient to hang during use.

In order to optimize the use effect of the sterile isolation cover 1 in the above embodiment, the sterile isolation cover 1 is equipped with a dust particle detection device, a planktonic bacteria monitoring device and a temperature and humidity monitoring device. By setting the above detection device and monitoring device, the aseptic state inside the sterile isolation cover 1 is ensured, so that the filling process can be carried out under good environmental conditions.

Each embodiment in this specification is described in a progressive manner, each embodiment focuses on the difference from other embodiments, and the same and similar parts of each embodiment can be referred to each other.

It should also be noted that in this specification, the term "comprises", "comprises" or any other variation thereof is intended to cover a non-exclusive inclusion, so that a process, method, article or device that includes a series of elements includes not only those elements, but also other elements not expressly listed, or elements inherent in the process, method, article, or apparatus. Without further limitations, an element defined by the phrase "comprising a ..." does not exclude the presence of additional identical elements in the process, method, article or apparatus comprising said element.

The above description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the invention. Therefore, the present invention will not be limited to the embodiments shown herein, but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (9)

1. a kind of full-automatic exhaust fills aseptic filling and sealing machine, it is characterised in that including being provided with the aseptic cage with liquid charging aperture (11) (1) what and the embedding streamline that is installed in the aseptic cage (1), the embedding streamline included setting gradually is upper packed (2), trimming device (3), filling apparatus (4), closing device and lower bagging apparatus (5) are put, is also included for soft bag (9) and the filling The conveyer of envelope streamline relative motion.

2. full-automatic exhaust according to claim 1 fills aseptic filling and sealing machine, it is characterised in that the conveyer includes annular Transfer assembly (7), the conveyer are connected with power distribution cabinet (8).

3. full-automatic exhaust according to claim 2 fills aseptic filling and sealing machine, it is characterised in that the upper bagging apparatus (2) includes For gripping the upper bag fixture (21) of the soft bag (9), the annular transfer assembly (7) is provided with for clamping the soft bag (9) embedding clamp (71).

4. full-automatic exhaust according to claim 3 fills aseptic filling and sealing machine, it is characterised in that the trimming device 3 includes using In the cutter sweep in the sealed bottom area for holding down assembly (31) and being used to cut away the soft bag (9) for compressing the soft bag (9) (32), also include taking slitter edge device (33) for take slitter edge away.

5. full-automatic exhaust according to claim 4 fills aseptic filling and sealing machine, it is characterised in that the filling apparatus (4) include For compressing the bag pressing component (41) of the soft bag (9) and for the filling pressure assembly with liquid (42), also including for circulating The filling pipeline (43) with liquid.

6. full-automatic exhaust according to claim 5 fills aseptic filling and sealing machine, it is characterised in that the closing device include for Weld the sealing die at the opening of the soft bag (9).

7. full-automatic exhaust according to claim 6 fills aseptic filling and sealing machine, it is characterised in that also include positioned at described packed The cleaning device (6) between (2) and the trimming device (3) is put, the cleaning device (6) is including ion wind air blowing component (61), pneumatic module (62) and air return pipeline (63) are collected.

8. full-automatic exhaust according to claim 7 fills aseptic filling and sealing machine, it is characterised in that also include positioned at the sealing dress Put and the hole punched device between the lower bagging apparatus (5), the hole punched device is for opening up extension in the afterbody of the soft bag (9) Hole.

9. full-automatic exhaust according to any one of claim 1 to 8 fills aseptic filling and sealing machine, it is characterised in that it is described it is aseptic every Dust particle detection means, flcating germ monitoring device and humiture monitoring device are provided with from cover (1).