CN106053587B - Spatial discrimination map acquires equipment, fluorography equipment and ionic migration spectrometer - Google Patents
Spatial discrimination map acquires equipment, fluorography equipment and ionic migration spectrometer Download PDFInfo
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- CN106053587B CN106053587B CN201610343841.1A CN201610343841A CN106053587B CN 106053587 B CN106053587 B CN 106053587B CN 201610343841 A CN201610343841 A CN 201610343841A CN 106053587 B CN106053587 B CN 106053587B
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- 238000009791 electrochemical migration reaction Methods 0.000 title claims abstract description 25
- 150000002500 ions Chemical class 0.000 claims abstract description 60
- 230000005012 migration Effects 0.000 claims abstract description 28
- 238000013508 migration Methods 0.000 claims abstract description 28
- 230000033001 locomotion Effects 0.000 claims abstract description 20
- 230000005284 excitation Effects 0.000 claims description 19
- 230000007246 mechanism Effects 0.000 claims description 7
- 230000005855 radiation Effects 0.000 claims description 5
- 238000000926 separation method Methods 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 3
- 238000001514 detection method Methods 0.000 abstract description 5
- 238000001871 ion mobility spectroscopy Methods 0.000 abstract description 5
- 238000000034 method Methods 0.000 description 7
- 230000008569 process Effects 0.000 description 5
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 230000005684 electric field Effects 0.000 description 3
- 238000001228 spectrum Methods 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 230000003595 spectral effect Effects 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- 230000009471 action Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000005094 computer simulation Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 238000000132 electrospray ionisation Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- VYXSBFYARXAAKO-UHFFFAOYSA-N ethyl 2-[3-(ethylamino)-6-ethylimino-2,7-dimethylxanthen-9-yl]benzoate;hydron;chloride Chemical compound [Cl-].C1=2C=C(C)C(NCC)=CC=2OC2=CC(=[NH+]CC)C(C)=CC2=C1C1=CC=CC=C1C(=O)OCC VYXSBFYARXAAKO-UHFFFAOYSA-N 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 238000004020 luminiscence type Methods 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000012916 structural analysis Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
- G01N27/622—Ion mobility spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/06—Illumination; Optics
- G01N2201/061—Sources
- G01N2201/06113—Coherent sources; lasers
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- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Abstract
A kind of spatial discrimination map acquisition equipment for ionic migration spectrometer, ionization source including generating fluorescent samples ion, the receiver board for separating the migration tube of sample ions and being set at the migration tube output port, during the receiver board receives fluorescent samples ion, the output port of the receiver board and the migration tube relatively moves, so that the different plate face regions of the receiver board successively capture the fluorescent samples ion for arriving at the receiver board by mobility sequence, wherein the rate of the relative movement is greater than or equal to the movement rate of fluorescent samples ion, to the fluorescent samples ion of expansion strike thereon on the receiver board.A kind of fluorography equipment used with spatial discrimination map acquisition equipment ion complex is also disclosed herein, and there is spatial discrimination map acquisition equipment and the fluorography equipment ionic migration spectrometer.The present invention changes the traditional detection mode of ionic migration spectrometer to improve the detectability of ion mobility spectrometry.
Description
Technical field
The present invention relates to ionic migration spectrometer more particularly to a kind of spatial discrimination map acquisitions for ionic migration spectrometer
Equipment, fluorography equipment and the ionic migration spectrometer with above equipment.
Background technique
The usual structure of fluorescent molecule headed by large biological molecule albumen is complex and has corresponding with steric configuration
Biological nature, ionic migration spectrometer can be carried out structural analysis and ground by special resolved way (mobility) to such molecule
Study carefully.Especially close to some mass-to-charge ratioes or arrangement biggish fluorescent molecule of same space configuration difference.
Currently, the detection of sample ions mobility is usually using ionic current on detector to the two-dimensional curve of drift time
It obtains its time step and differentiates spectrogram.Time step should be readily appreciated that and operate as the comparison axis of ion transfer spectrogram.Analysis is not
When with sample, since the sample after being ionized has specific migration rate under electric field and air-flow double action, so moving
Moving in pipe sequentially space arrangement to be distributed.Arrival corresponding with its migration rate is shown by identical migration distance
Time, so that obtaining corresponding time step differentiates spectrogram, user is usually with the progress of time corresponding to sample ions spectral peak
Analysis.
It but can not be more than the time of detection system by time spectrum detector response time restriction during actual acquisition
Response speed, sample separating capacity similar for mobility are limited.The gain bandwidth of detection circuit in addition to this, ion are being examined
Electric field change caused by the attaching process and metal detection electrode of survey all can the analysis performance to instrument itself have an impact.Another party
Face, researcher generally pass through Computer Simulation and determine movement process of the ion in migration tube.It tests utilizing to Ion transfer
When spectral theory is proved, motion process can only be deduced from the transient state transit time spectrogram that ion arrives at.
Summary of the invention
It is a primary object of the present invention to overcome the deficiencies of the prior art and provide a kind of space for ionic migration spectrometer
Resolution map acquires equipment, fluorography equipment and the ionic migration spectrometer with above equipment, improves ion mobility spectrometry
Detectability.
To achieve the above object, the invention adopts the following technical scheme:
A kind of spatial discrimination map acquisition equipment for ionic migration spectrometer, the ionization including generating fluorescent samples ion
The migration tube in source and separation sample ions, further includes the receiver board being set at the output port of the migration tube, connects described
During receiving plate reception fluorescent samples ion, the output port of the receiver board and the migration tube is relatively moved, with
The different plate face regions of the receiver board are made successively to capture the fluorescent samples ion for arriving at the receiver board by mobility sequence,
Described in relative movement rate be greater than or equal to movement rate of the fluorescent samples ion in the migration tube, thus described
The fluorescent samples ion of expansion strike thereon on receiver board.
Further:
The receiver board is the turntable for being coupled to driving mechanism, during receiving fluorescent samples ion, the driving
Mechanism drives the turntable to rotate in one direction.
Movement of the receiving plane moving direction of the receiver board perpendicular to the fluorescent samples ion exported from the migration tube
Direction.
The plate of the receiver board be do not influence ionic migration spectrometer work normally field distribution and can adhere to sample from
The material of son.
The ion gate that the ionization source is controlled during one acquisition periodically turns on, and the time point opened every time is equal
The time point that some particular point of rotation is turned to corresponding to the turntable, the duration opened every time are rotated no more than the turntable
One week time.
The ionization source is the soft ionization source that ionization mode does not influence sample to be tested fluorescent characteristic.
A kind of fluorography equipment used with the spatial discrimination map acquisition equipment ion complex, including exciting light
Exciting light is radiated on the receiver board by source and fluorescent samples spectrogram filming apparatus, the excitation light source, makes the receiver board
On fluorescent samples issue fluorescent photon, the fluorescent samples spectrogram filming apparatus shoot the fluorescent samples on the receiver board spectrum
Figure, to obtain the spatial discrimination spectrogram.
Further:
Semi-transparent semi-reflecting lens, the excitation that the excitation light source issues are provided between the excitation light source and the receiver board
Light is radiated on the receiver board through the semi-transparent semi-reflecting lens, the fluorescent samples stimulated radiation on the receiver board it is glimmering
Light photon is reflected by the semi-transparent semi-reflecting lens in the direction of the fluorescent samples spectrogram filming apparatus, it is preferable that is swashed described
The convex lens of the excitation beam for obtaining predetermined diameter is provided between light emitting source and the semi-transparent semi-reflecting lens.
Filter mirror is provided between the fluorescent samples spectrogram filming apparatus and the semi-transparent semi-reflecting lens with by predetermined model
The exciting light for the low band enclosed removes.
A kind of ionic migration spectrometer, including the spatial discrimination map acquisition equipment and the fluorography equipment.
Beneficial effects of the present invention:
Since fluorescent samples molecule has specific elemental composition and space structure, to its nature examination and resolution capability
Research process intermediate ion mobility spectrometer the mobility of tie element can be provided and sample can be divided using mobility
It distinguishes and screens.But the sample message that the mode of simple time step resolution spectrogram obtains in terms of resolution capability and result has
Limit, needs special method to be improved with means.The present invention provides a kind of spatial discrimination map for ionic migration spectrometer
Equipment, fluorography equipment and the ionic migration spectrometer with above equipment are acquired, the tradition inspection of ionic migration spectrometer is changed
Survey mode obtains the spatial discrimination spectrogram of sample, so that ion be overcome to move for fluorescent characteristic molecule in ionic migration spectrometer
The drawbacks of spectrometer is detected using time spectrum is moved, the detectability of ion mobility spectrometry is effectively improved.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the spatial discrimination map acquisition equipment of an embodiment of the present invention；
Fig. 2 is the structural schematic diagram of the fluorography equipment of an embodiment of the present invention；
Fig. 3 is a kind of specific embodiment spatial discrimination spectrogram obtained of the present invention.
Description of symbols:
1- ionization source, 2- migration tube, 3- servo motor, 4- transmission shaft, 5- receiver board, 6- semi-transparent semi-reflecting lens, 7- filter mirror,
8- excitation light source, 9,10- convex lens, 11- camera, 12- camera lens.
Specific embodiment
It elaborates below to embodiments of the present invention.It is emphasized that following the description is only exemplary,
The range and its application being not intended to be limiting of the invention.
Refering to fig. 1 and Fig. 2, in one embodiment, a kind of spatial discrimination map acquisition for ionic migration spectrometer is set
It is standby, it further include being set to the migration including generating the ionization source 1 of fluorescent samples ion and the migration tube 2 of separation sample ions
Receiver board 5 at the output port of pipe 2, during the receiver board 5 receives fluorescent samples ion, the receiver board 5 with
The output port of the migration tube 2 relatively moves, so that the different plate face regions of the receiver board are successively captured by migration
Rate sequence arrives at the fluorescent samples ion of the receiver board, wherein the rate of the relative movement be greater than or equal to fluorescent samples from
The movement rate of son, thus the fluorescent samples ion of expansion strike thereon on the receiver board 5.
In a particular embodiment, the relative movement mode is realized either driving receiver board 5 is moved relative to migration tube 2
It is dynamic, it is also possible to drive migration tube 2 mobile relative to receiver board 5, the two while movement can also be driven.
In a preferred embodiment, the receiver board 5 is the turntable for being coupled to driving mechanism, is receiving fluorescent samples ion
During, the driving mechanism drives the turntable to rotate in one direction.Specifically, driving mechanism may include servo electricity
Machine 3, servo motor 3 drive turntable rotation by transmission shaft 4.In further embodiments, it can also be connect using linearly moving
Receive plate.
In a preferred embodiment, the receiving plane moving direction of the receiver board 5 is perpendicular to exporting from the migration tube 2
The direction of motion of fluorescent samples ion.Preferably, receiving plane and receiving plane moving direction are on the same face.For example, receiver board 5 is
Turntable, the direction of motion of the disc surfaces perpendicular to fluorescent samples ion, the shaft and the direction of motion of fluorescent samples ion of turntable
In parallel.
In a preferred embodiment, the plate of the receiver board 5 is not influence ionic migration spectrometer to work normally electric field point
Cloth and the material that sample ions can be adhered to.The receiver board 5 can be cardboard, glass plate or rubber slab etc..The tool of receiver board 5
Shape can determine according to actual needs.
In a preferred embodiment, the ion gate that the ionization source 1 is controlled during one acquisition periodically turns on,
The time point opened every time both corresponds to the time point that the turntable turns to some particular point of rotation, the duration opened every time
No more than the time that the turntable rotates one week.
In a preferred embodiment, the ionization source 1 does not influence the soft of sample to be tested fluorescent characteristic using ionization mode
Ionization source.Ionization source 1 can be electron spray (ESI) ionization source.
A kind of fluorography equipment used with the spatial discrimination map acquisition equipment ion complex, including exciting light
Exciting light is radiated on the receiver board 5 by source and fluorescent samples spectrogram filming apparatus, the excitation light source, makes the receiver board
Fluorescent samples on 5 issue fluorescent photon, and the fluorescent samples spectrogram filming apparatus shoots the fluorescent samples on the receiver board 5
Spectrogram, to obtain the spatial discrimination spectrogram.Fluorescent samples spectrogram filming apparatus may include camera 11 and camera lens 12.
In a preferred embodiment, semi-transparent semi-reflecting lens 6, institute are provided between the excitation light source 8 and the receiver board 5
The exciting light for stating the sending of excitation light source 8 is radiated on the receiver board 5 through the semi-transparent semi-reflecting lens 6, on the receiver board 5
The fluorescent photon of the fluorescent samples stimulated radiation, which reflects to shoot in the fluorescent samples spectrogram by the semi-transparent semi-reflecting lens 6, to be filled
The direction set, it is preferable that convex lens 9,10 is provided between the excitation light source 8 and the semi-transparent semi-reflecting lens 6, for obtaining
The excitation beam of predetermined diameter.
In a preferred embodiment, it is arranged between the fluorescent samples spectrogram filming apparatus and the semi-transparent semi-reflecting lens 6
There is filter mirror 7, filter mirror 7 is used to remove the exciting light of the low band of preset range.
A kind of ionic migration spectrometer, including the spatial discrimination map acquisition equipment and the fluorography equipment.
In some embodiments, sample used in spatial discrimination map acquisition equipment is that its sample ions has in certain wave
Duan Guangzhao, which is penetrated down, reaches radiation transistion caused by the first electron excitation singlet state and the fluorescent samples of adjoint luminous power.Ionization
Source makes sample ionization using soft ionization source, in order to avoid influence sample to be tested fluorescent characteristic.Ionic migration spectrometer is floated using ion
The difference of shift time carries out the separation and judgement of sample ions.Corresponding with Conventional temporal spectrogram, spatial discrimination spectrogram refers to
It is with space length for a digit separator ionic strength.
In some embodiments, fluorography device makes its sending by the fluorescent samples that exciting light irradiates on receiver board 5
Fluorescent photon, the fluorescent samples spectrogram in the case where the front of receiver board 5 is using camera shooting on receiver board 5.Wherein video camera with
The exciting light of low band is removed using high-pass filtering mirror between receiver board 5, whole developing process is in impermeable extraneous natural light
It is carried out in darkroom.
Example
(1) the migration pipe diameter 16mm of ion mobility spectrometry, apparatus structure make outer edge and the migration bore outer of turntable
It is preferred that tangent.Radius is used to substitute traditional detector, 300 μ of ion gate opening time as receiver board for 10cm glass disk
m.Sample ions remain a constant speed substantially in migration tube after undergoing one section of variable accelerated motion and move to receiver board after enabling, receive
Plate successively capture the ion that strikes against its surface and keep not interfering ion surface remove receiver board.It is placed in fluorography dress
In setting, the sample was photographed in camera in the spatial discrimination spectrogram case of ion mobility spectrometry.
(2) wherein indicate scale on receiver board, when the scale is run to 12 directions, triggering ion gate is opened every time,
Angular velocity of satellite motion keeps stablizing on rotation roulette where receiver board.
(3) wherein sample is the RHODAMINE 6G (Shanghai Jing Chun biochemical technology limited liability company) with the characteristics of luminescence
A kind of soluble easily in water and methanol, dyestuff to shine in yellow green, is used widely in chemical industry.Apply electrospray ionisation source
5kV voltage, migration tube voltage are 50V/mm.
(4) excitation light source issues 473nm laser, obtains 30mm diameter beam by expanding, excites the fluorescence on receiver board
Sample.The fluorescent photon of sample stimulated radiation is reflected by semi-transparent semi-reflecting lens in camera direction.Camera passes through filter mirror and camera lens
The light of reflection is filtered and collects to obtain spectrogram, as shown in Figure 3.
The above content is combine it is specific/further detailed description of the invention for preferred embodiment, cannot recognize
Fixed specific implementation of the invention is only limited to these instructions.For those of ordinary skill in the art to which the present invention belongs,
Without departing from the inventive concept of the premise, some replacements or modifications can also be made to the embodiment that these have been described,
And these substitutions or variant all shall be regarded as belonging to protection scope of the present invention.
Claims (11)
1. a kind of spatial discrimination map for ionic migration spectrometer acquires equipment, the ionization source including generating fluorescent samples ion
With the migration tube of separation fluorescent samples ion, which is characterized in that further include being set to connecing at the output port of the migration tube
Plate is received, during the receiver board receives fluorescent samples ion, the output port of the receiver board and the migration tube is sent out
Raw relative movement, so that the different plate face regions of the receiver board successively capture and arrive at the glimmering of the receiver board by mobility sequence
Light sample ions, wherein the rate of the relative movement is greater than or equal to the movement rate of fluorescent samples ion, thus described
The fluorescent samples ion of expansion strike thereon on receiver board.
2. spatial discrimination map as described in claim 1 acquires equipment, which is characterized in that the receiver board is to be coupled to driving
The turntable of mechanism, during receiving fluorescent samples ion, the driving mechanism drives the turntable to rotate in one direction.
3. spatial discrimination map as described in claim 1 acquires equipment, which is characterized in that the receiving plane of the receiver board is mobile
The direction of motion of the direction perpendicular to the fluorescent samples ion exported from the migration tube.
4. spatial discrimination map as described in claim 1 acquires equipment, which is characterized in that the plate of the receiver board is not shadow
Ionic migration spectrometer is rung to work normally field distribution and the material of sample ions can be adhered to.
5. spatial discrimination map as claimed in claim 2 acquires equipment, which is characterized in that control institute during one acquisition
The ion gate for stating ionization source periodically turns on, and the time point opened every time both corresponds to the turntable and turns to some specific turn
The time point of dynamic position, the duration opened every time rotate one week time no more than the turntable.
6. spatial discrimination map as described in claim 1 acquires equipment, which is characterized in that the ionization source be ionization mode not
Influence the soft ionization source of sample to be tested fluorescent characteristic.
7. a kind of fluorescence used with spatial discrimination map as claimed in any one of claims 1 to 6 acquisition equipment ion complex is aobvious
Shadow equipment, which is characterized in that including excitation light source and fluorescent samples spectrogram filming apparatus, the excitation light source irradiates exciting light
On the receiver board, the fluorescent samples on the receiver board is made to issue fluorescent photon, the fluorescent samples spectrogram filming apparatus
The fluorescent samples spectrogram on the receiver board is shot, to obtain the spatial discrimination spectrogram.
8. the fluorography equipment that spatial discrimination map acquisition equipment ion complex as claimed in claim 7 uses, feature
It is, semi-transparent semi-reflecting lens, the exciting light that the excitation light source issues is provided between the excitation light source and the receiver board
It is radiated on the receiver board through the semi-transparent semi-reflecting lens, the fluorescence of the fluorescent samples stimulated radiation on the receiver board
Photon is reflected by the semi-transparent semi-reflecting lens in the direction of the fluorescent samples spectrogram filming apparatus.
9. the fluorography equipment that spatial discrimination map acquisition equipment ion complex as claimed in claim 8 uses, feature
It is, the convex lens of the excitation beam for obtaining predetermined diameter is provided between the excitation light source and the semi-transparent semi-reflecting lens
Mirror.
10. the fluorography equipment that spatial discrimination map acquisition equipment ion complex as claimed in claim 8 uses, feature
It is, is provided with filter mirror between the fluorescent samples spectrogram filming apparatus and the semi-transparent semi-reflecting lens with by preset range
The exciting light of low band removes.
11. a kind of ionic migration spectrometer, which is characterized in that adopted including spatial discrimination map as claimed in any one of claims 1 to 6
Collect equipment and the described in any item fluorography equipment of claim 7 to 10.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610343841.1A CN106053587B (en) | 2016-05-23 | 2016-05-23 | Spatial discrimination map acquires equipment, fluorography equipment and ionic migration spectrometer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610343841.1A CN106053587B (en) | 2016-05-23 | 2016-05-23 | Spatial discrimination map acquires equipment, fluorography equipment and ionic migration spectrometer |
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| CN106053587A CN106053587A (en) | 2016-10-26 |
| CN106053587B true CN106053587B (en) | 2019-01-11 |
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2016
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5345809A (en) * | 1989-06-09 | 1994-09-13 | Research Corporation Technologies, Inc. | Explosive detection screening system |
| EP0447158A2 (en) * | 1990-03-13 | 1991-09-18 | Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Revenue | Detector for concealed explosive or narcotic substances |
| US20030132379A1 (en) * | 2002-01-17 | 2003-07-17 | Gangqiang Li | Ion mobility spectrometer with high ion transmission efficiency |
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| CN106053587A (en) | 2016-10-26 |
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