CN1060352C - Blood-fat reducing medicine and preparing process thereof - Google Patents
Blood-fat reducing medicine and preparing process thereof Download PDFInfo
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- CN1060352C CN1060352C CN96102687A CN96102687A CN1060352C CN 1060352 C CN1060352 C CN 1060352C CN 96102687 A CN96102687 A CN 96102687A CN 96102687 A CN96102687 A CN 96102687A CN 1060352 C CN1060352 C CN 1060352C
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- 239000003814 drug Substances 0.000 title claims abstract description 20
- 238000000034 method Methods 0.000 title claims abstract 3
- 238000002156 mixing Methods 0.000 claims abstract description 4
- 239000000843 powder Substances 0.000 claims description 10
- 239000009636 Huang Qi Substances 0.000 claims description 9
- 241000005787 Cistanche Species 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 229940079593 drug Drugs 0.000 claims description 4
- 150000002632 lipids Chemical class 0.000 claims description 4
- 239000002994 raw material Substances 0.000 claims description 4
- 238000001035 drying Methods 0.000 claims description 3
- 239000000706 filtrate Substances 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 2
- 239000006187 pill Substances 0.000 claims description 2
- 238000010298 pulverizing process Methods 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 abstract description 9
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- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract description 8
- 201000005577 familial hyperlipidemia Diseases 0.000 abstract description 6
- 210000004204 blood vessel Anatomy 0.000 abstract description 4
- 235000012000 cholesterol Nutrition 0.000 abstract description 4
- 230000000694 effects Effects 0.000 abstract description 4
- 208000004930 Fatty Liver Diseases 0.000 abstract description 3
- 206010019708 Hepatic steatosis Diseases 0.000 abstract description 3
- 230000017531 blood circulation Effects 0.000 abstract description 3
- 208000010706 fatty liver disease Diseases 0.000 abstract description 3
- 230000037356 lipid metabolism Effects 0.000 abstract description 3
- 231100000240 steatosis hepatitis Toxicity 0.000 abstract description 3
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract description 3
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 2
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- 210000004185 liver Anatomy 0.000 abstract description 2
- 210000000952 spleen Anatomy 0.000 abstract description 2
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- 244000233890 Alisma plantago Species 0.000 abstract 1
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- 206010002482 Angiosclerosis Diseases 0.000 abstract 1
- 241001061264 Astragalus Species 0.000 abstract 1
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 241000132012 Atractylodes Species 0.000 abstract 1
- 206010008190 Cerebrovascular accident Diseases 0.000 abstract 1
- 241000336315 Cistanche salsa Species 0.000 abstract 1
- 240000004307 Citrus medica Species 0.000 abstract 1
- 235000014375 Curcuma Nutrition 0.000 abstract 1
- 244000164480 Curcuma aromatica Species 0.000 abstract 1
- 241000893536 Epimedium Species 0.000 abstract 1
- 241000195955 Equisetum hyemale Species 0.000 abstract 1
- 102000015779 HDL Lipoproteins Human genes 0.000 abstract 1
- 108010010234 HDL Lipoproteins Proteins 0.000 abstract 1
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- 235000006508 Nelumbo nucifera Nutrition 0.000 abstract 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 abstract 1
- 244000153955 Reynoutria sachalinensis Species 0.000 abstract 1
- 235000003202 Reynoutria sachalinensis Nutrition 0.000 abstract 1
- 244000299790 Rheum rhabarbarum Species 0.000 abstract 1
- 235000009411 Rheum rhabarbarum Nutrition 0.000 abstract 1
- 240000006079 Schisandra chinensis Species 0.000 abstract 1
- 235000008422 Schisandra chinensis Nutrition 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 208000029078 coronary artery disease Diseases 0.000 abstract 1
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 abstract 1
- 235000018905 epimedium Nutrition 0.000 abstract 1
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- 230000002526 effect on cardiovascular system Effects 0.000 description 2
- 230000001575 pathological effect Effects 0.000 description 2
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- 208000000501 Lipidoses Diseases 0.000 description 1
- 206010024585 Lipidosis Diseases 0.000 description 1
- 208000005946 Xerostomia Diseases 0.000 description 1
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- 235000009508 confectionery Nutrition 0.000 description 1
- -1 decoct Substances 0.000 description 1
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- 125000005456 glyceride group Chemical group 0.000 description 1
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Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a medicine for treating the diseases of hyperlipemia, fatty liver, adiposis, atherosclerosis of arteries blood vessel, coronary heart disease, apoplexy, etc. and a preparation method of the medicine. The medicine comprises the following components of giant knotweed rhizome, curcuma roots, citron peel, lotus leaves, raw haws, raw astragalus roots, schisandra fruits, fried white atractylodes rhizome, glossy privet fruits, broomrape, epimedium, rhubarb horsetail and water plantain through the processes of crushing, mixing, decoction and concentration. The present invention has the efficacy of strengthening a liver and a spleen, tonifying Qi of kidneys and activating blood circulation to dissipate blood stasis. The present invention also has the curative effects of reducing the contents of cholesterol and triglyceride in blood, increasing the content of high-density lipoprotein, accelerating lipid metabolism and slowing down the speed of angiosclerosis.
Description
The present invention discloses a kind of Chinese patent medicine for the treatment of diseases such as hyperlipemia, fatty liver, obesity, arteries is atherosis and preparation method thereof.
Hyperlipemia is meant a kind of pathological state when one or more components and concentrations surpass arm's length standard in the blood plasma matter.Blood fat mainly is made up of cholesterol, glyceride, phospholipid, free fatty etc.In the clinical practice, finding that cardiovascular and cerebrovascular disease is many usually to deposit a large amount of lipids in the speckle of patient vessel's wall because of arteriosclerosis causes, illustrate that hyperlipemia is not only the key factor of facilitating arteriosclerosis to develop, also is the pathologic basis of cardiovascular and cerebrovascular disease.Defectives such as therefore, medical circle is generally built consensus, and promptly can reduce the hardened sickness rate of artery by reducing hyperlipidemia, reaches the purpose of treatment hyperlipemia, and the Western medicine blood fat reducing exists poor stability, and recurrence, and side effect easily is bigger.
The object of the present invention is to provide a kind of traditional Chinese medical science medicine and preparation method thereof, the content by cholesterol and triglyceride in the reduction blood increases its hdl concentration, quickens lipid metabolism, and sclerosis of blood vessels speed slows down.
The present invention is the purpose that reaches the treatment hyperlipemia by the Chinese medicine that adopts following raw materials according: Rhizoma Polygoni Cuspidati 6～8%, Radix Curcumae 6～8%, Pericarpium Citri 6～8%, Folium Nelumbinis 4～6%, Rhizoma Alismatis 4～6%, Fructus Crataegi 12～15%, Radix Astragali 8～10%, Pericarpium citri reticuatae chachiensis 3～6%, Fructus Amomi 3～5%, Fructus Schisandrae Chinensis 6～8%, Rhizoma Atractylodis Macrocephalae (parched) 6～10%, Fructus Ligustri Lucidi 6～10%, Herba Cistanches 6～8%, Herba Epimedii 6～10%, Radix Et Rhizoma Rhei 1.5～4%.
Above-mentioned preparation method of Chinese medicine may further comprise the steps: earlier Rhizoma Polygoni Cuspidati, Radix Curcumae, Rhizoma Alismatis, Fructus Crataegi, Radix Astragali, Rhizoma Atractylodis Macrocephalae (parched), Radix Et Rhizoma Rhei are mixed, be ground into fine powder, again remaining medicine is decocted with water secondary, merging filtrate, be concentrated into the 1 gram content that every milliliter of concentrated solution is equivalent to crude drug in whole, with above-mentioned fine powder mixing after drying, this fine powder is further pulverized milled then, sieve; Fine powder is with water pill or incapsulate.
Fat reducing pill provided by the present invention or capsule are pure Chinese medicinal preparation, show through clinical use, have the liver soothing and the spleen invigorating, tonify Qi of the kidney, the effect of blood circulation promoting and blood stasis dispelling, can reduce the content of cholesterol and triglyceride in the blood, increase its hdl concentration; Blood viscosity lowering, the lipidosis of removing blood vessel wall improves blood circulation, quickens lipid metabolism, and sclerosis of blood vessels speed slows down.
Embodiment
Take by weighing former medicine by following component and content thereof: Rhizoma Polygoni Cuspidati 6～8%, Radix Curcumae 6～8%, Pericarpium Citri 6～8%, Folium Nelumbinis 4～6%, Rhizoma Alismatis 4～6%, %, Fructus Crataegi 12～15%, Radix Astragali 8～10%, Pericarpium citri reticuatae chachiensis 3～6%, Fructus Amomi 3～5%, Fructus Schisandrae Chinensis 6～8%, Rhizoma Atractylodis Macrocephalae (parched) 6～10%, Fructus Ligustri Lucidi 6～10%, Herba Cistanches 6～8%, Herba Epimedii 6～10%, Radix Et Rhizoma Rhei 1.5～4%.
Earlier Rhizoma Polygoni Cuspidati, Radix Curcumae, Rhizoma Alismatis, Fructus Crataegi, Radix Astragali, Rhizoma Atractylodis Macrocephalae (parched), Radix Et Rhizoma Rhei are mixed, be ground into fine powder, again remaining medicine is decocted with water secondary, merging filtrate, be concentrated into to a certain degree, concentrating degree is grasped the 1 gram content that is equivalent to crude drug in whole at every milliliter of concentrated solution, with above-mentioned fine powder and concentrated solution mixing after drying, further pulverize then and mill, sieve; Make ball or capsule gets final product.
Rhizoma Polygoni Cuspidati in the above raw material, Radix Astragali, Herba Cistanches, Fructus Ligustri Lucidi four flavor owners want component, all belong to necessary component outward and remove Pericarpium citri reticuatae chachiensis, Fructus Amomi, in the medication preparation process, its color is gradually changed by yellowish → deep yellow → brown, fragrant odour, suffering, hardship, little sweet.
Has optimum curative effect through clinical use following component of proof and content;
Rhizoma Polygoni Cuspidati 12g, Radix Curcumae 12g, Pericarpium Citri 12g, Folium Nelumbinis 10g, Rhizoma Alismatis 10g, Fructus Crataegi 20g, Radix Astragali 15g, Pericarpium citri reticuatae chachiensis 10g, Fructus Amomi 6g, Fructus Schisandrae Chinensis 10g, Rhizoma Atractylodis Macrocephalae (parched) 12g, Fructus Ligustri Lucidi 12g, Herba Cistanches 10g, Herba Epimedii 10g, Radix Et Rhizoma Rhei 4g.
The above institute weight that provides adopts content to represent:
Rhizoma Polygoni Cuspidati 7.3%, Radix Curcumae 7.3%, Pericarpium Citri 7.3%, Folium Nelumbinis 6%, Rhizoma Alismatis 6%, Fructus Crataegi 12.1%, Radix Astragali 9.2%, Pericarpium citri reticuatae chachiensis 6%, Fructus Amomi 3.6%, Fructus Schisandrae Chinensis 6%, Rhizoma Atractylodis Macrocephalae (parched) 7.3%, Fructus Ligustri Lucidi 7.3%, Herba Cistanches 6%, Herba Epimedii 6%, Radix Et Rhizoma Rhei 2.6%.
With the medicine of above-mentioned content according to described preparation method via pulverizing, mix, decoct, concentrate encapsulated or making ball.
Clinical observation, after the course of treatment (three months) of taking medicine, TG descends and reaches 75%, and TCH descends and reaches 60%, and HDL-CH rises 75%; Fatty liver disappears; 80% above patient take medicine back xerostomia hardship, uncomfortable in chest, weak, breathe hard, receive food, defecation, picture of the tongue, pulse condition and all significantly improve, the present invention is a pure Chinese medicinal preparation, has no side effect.
Claims (2)
1. lipid lowerers, it is made by following raw materials according: Rhizoma Polygoni Cuspidati 6～8%, Radix Curcumae 6～8%, Pericarpium Citri 6～8%, Folium Nelumbinis 4～6%, Rhizoma Alismatis 4～6%, Fructus Crataegi 12～15%, Radix Astragali 8～10%, Pericarpium citri reticuatae chachiensis 3～6%, Fructus Amomi 3～5%, Fructus Schisandrae Chinensis 6～8%, Rhizoma Atractylodis Macrocephalae (parched) 6～1 0%, Fructus Ligustri Lucidi 6～1 0%, Herba Cistanches 6～8%, Herba Epimedii 6～10%, Radix Et Rhizoma Rhei 1.5～4%, above raw material forms through pulverizing, mix, decoct, concentrating.
2. method for preparing the described lipid lowerers of claim 1, comprise the following steps: earlier Rhizoma Polygoni Cuspidati, Radix Curcumae, Rhizoma Alismatis, Fructus Crataegi, Radix Astragali, Rhizoma Atractylodis Macrocephalae (parched), Radix Et Rhizoma Rhei to be mixed, be ground into fine powder, again remaining medicine is decocted with water secondary, merging filtrate is concentrated into the 1 gram content that every milliliter of concentrated solution is equivalent to crude drug in whole, with above-mentioned fine powder mixing after drying, then this fine powder is further pulverized and milled, sieve; Fine powder is with water pill or incapsulate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96102687A CN1060352C (en) | 1996-02-08 | 1996-02-08 | Blood-fat reducing medicine and preparing process thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96102687A CN1060352C (en) | 1996-02-08 | 1996-02-08 | Blood-fat reducing medicine and preparing process thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1156601A CN1156601A (en) | 1997-08-13 |
| CN1060352C true CN1060352C (en) | 2001-01-10 |
Family
ID=5117689
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN96102687A Expired - Fee Related CN1060352C (en) | 1996-02-08 | 1996-02-08 | Blood-fat reducing medicine and preparing process thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1060352C (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100531596C (en) * | 2003-08-18 | 2009-08-26 | 高思 | Health food |
| US20050267221A1 (en) * | 2004-05-14 | 2005-12-01 | Research Development Foundation | Use of curcumin and analogues thereof as inhibitors of ACC2 |
| CN102688451B (en) * | 2012-05-25 | 2013-08-21 | 王兴辉 | Chinese medicinal composition for treating alcoholic fatty liver |
| US9668999B2 (en) * | 2014-04-23 | 2017-06-06 | Semi Labs Limited | Method for the treatment of hypercholesterolemia |
| CN104547958A (en) * | 2015-02-09 | 2015-04-29 | 王士国 | Traditional Chinese medicine preparation with effects of promoting digestion and reducing lipid and preparation method |
| CN104857377B (en) * | 2015-05-21 | 2018-05-01 | 圣原健康产业有限公司 | Improve Chinese medical extract of fatty liver and preparation method thereof and massage cream |
| CN105265971A (en) * | 2015-09-14 | 2016-01-27 | 李加义 | Weight losing drink for middle-aged men |
| CN107648470A (en) * | 2017-10-24 | 2018-02-02 | 马敏 | A kind of medicine for treating hyperlipemia and preparation method thereof |
| CN118615413B (en) * | 2024-07-30 | 2025-05-27 | 黑龙江中医药大学 | Traditional Chinese medicine composition and preparation for preventing and treating nonalcoholic fatty liver disease and preparation method |
-
1996
- 1996-02-08 CN CN96102687A patent/CN1060352C/en not_active Expired - Fee Related
Non-Patent Citations (1)
| Title |
|---|
| (中药大辞典)，第一版 1919.8.6 江苏新医学院，上海科学技术出版社 * |
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| Publication number | Publication date |
|---|---|
| CN1156601A (en) | 1997-08-13 |
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