CN105796461A - Moisturizing and repairing lotion containing hydrolyzed pearl essence flexible nano-liposomes and sea buckthron oil - Google Patents
Moisturizing and repairing lotion containing hydrolyzed pearl essence flexible nano-liposomes and sea buckthron oil Download PDFInfo
- Publication number
- CN105796461A CN105796461A CN201610162513.1A CN201610162513A CN105796461A CN 105796461 A CN105796461 A CN 105796461A CN 201610162513 A CN201610162513 A CN 201610162513A CN 105796461 A CN105796461 A CN 105796461A
- Authority
- CN
- China
- Prior art keywords
- skin
- pearl powder
- hydrolyzed pearl
- flexible nano
- liposomes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/413—Nanosized, i.e. having sizes below 100 nm
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cosmetics (AREA)
Abstract
本发明提供一种含有水解珍珠粉柔性纳米脂质体的沙棘油保湿修复乳，由水解珍珠粉柔性纳米脂质体、沙棘油、透明质酸、乳化剂、保湿剂、稳定剂和去离子水经乳化均质而成。本发明有效地增强皮肤表皮细胞和真皮的新陈代谢、修复皮肤的功能，柔性纳米脂质体能轻易穿透人体皮肤表层，使珍珠粉与细胞融合，发挥功效。辅以具有较强保湿修复作用的沙棘油、透明质酸作用于肌肤，能深入湿化角质形成细胞和强力水合作用以改善皮肤真皮的弹性，增强皮肤抵抗力，紧致肌肤，淡化细纹。本发明产品天然、温和、几乎无刺激，可长期用于皮肤屏障修复、润肤保湿、及皮肤年轻化之用。对干燥肤质、敏感肤质等有较好的补水保湿修复效果，并能有效净白肌肤、抗皱防老化。The invention provides a seabuckthorn oil moisturizing and repairing milk containing hydrolyzed pearl powder flexible nano-liposome, which consists of hydrolyzed pearl powder flexible nano-liposome, sea-buckthorn oil, hyaluronic acid, emulsifier, moisturizer, stabilizer and deionized water It is made by emulsification and homogenization. The invention effectively enhances the metabolism of skin epidermal cells and dermis, and repairs the skin, and the flexible nano liposome can easily penetrate the surface layer of human skin, so that pearl powder and cells can be fused to play a role. Supplemented with seabuckthorn oil and hyaluronic acid with strong moisturizing and repairing effects on the skin, it can deeply moisturize keratinocytes and powerful hydration to improve the elasticity of the skin dermis, enhance skin resistance, tighten the skin, and reduce fine lines . The product of the invention is natural, mild and almost non-irritating, and can be used for skin barrier repair, moisturizing and skin rejuvenation for a long time. It has a good moisturizing and repairing effect on dry skin and sensitive skin, and can effectively whiten the skin, anti-wrinkle and anti-aging.
Description
Technical field
The invention belongs to cosmetic product technical field, relate to a kind of skin care item, particularly relate to a kind of Oleum Hippophae moisturizing containing hydrolyzed pearl powder flexible nano-liposomes and repair breast, it is a kind of can solve the problem that skin is intensely dark, flexibility decrease, dry aging problem, the liposome skin care item that moisturizing repairing effect is good.
Background technology
Skin is made up of epidermis, corium, subcutaneous fat and appendages.Epidermal area is the outermost one layer of skin, is divided into from inside to outside: basal cell layer, prickle cell layer, granular cell layer, clear cell layer and keratinocyte layer.Skin appendages includes hair, hair follicle, sebaceous gland and sweat gland.Skin absorbs external substance mainly through three approach, i.e. horny layer, pilosebaceous unit and sweat duct mouth.Its mesocuticle is the most important approach of skin absorption, skin can only absorb some electrolyte under normal circumstances, small-molecule substance and liposoluble substance, can not directly absorb for some macro-molecular proteins, in daily life, most skin care milks are aqueous solutions, Margarita powder isoreactivity material is all water miscible, and the endogenous lipid of the exogenous lipid of horny layer secretion and sebaceous gland lipid secretion is oily matter, and water soluble nutrients chance oiliness lipid is insoluble, the water-soluble skin care product utilization rate thus resulting in routine is only small, use water-soluble skin care product for a long time, easily cause nutritional labeling waste and also easily block pore.
Pharmaceutical carrier lipid physical ability wetting surface skin, makes horny layer imbibition；Have an effect with keratodermatitis, change its ordered arrangement, make skin surface form reversible little space, medicine or drug-loaded liposome in moment and enter into deep skin (skin corium) by these spaces, thus being absorbed by organisms；With the sebaceous gland of skin surface, hair follicle, sweat gland mouth effect, make medicine or drug-loaded liposome arrive deep skin by these ducts, skin permeation of drugs had obvious facilitation.Flexible nano-liposomes particle diameter is little, height self-deformation, efficiently through the skin duct of several times less of himself, some macromolecular substances being difficult to transdermal can be made to be successfully entered skin, circulate even into body, the Cutaneous permeation of medicine is had significant facilitation.Flexible nano-liposomes can change the physicochemical property of proto-drug simultaneously, strengthens pharmacological action and the curative effect of medicine, improves bioavailability, be a kind of novel carrier for transdermal delivery.
Margarita is acknowledged as cosmetic good merchantable brand always, and its beauty treatment mechanism is to contain aminoacid and the trace element of various needed by human body in Margarita, and needed for the nutritional labeling contained in Margarita and mankind's skin, nutrient is close, is easy to be absorbed by the body, has the effect of whitening, speckle dispelling.The effective ingredient utilizing Margarita in current cosmetics mainly carries out with the form of hydrolyzed pearl powder, owing to Margarita containing various trace elements, electrical conductivity is higher, such as direct interpolation, it is easy to destroy the system of cosmetics, and be directly appended in cosmetics by Margarita hydrolyzed solution its effective ingredient and be easy to by other component breakage in cosmetics so that it is lose activity and be difficult to be absorbed by the body.Hydrolyzed pearl powder is prepared into flexible nano-liposomes; the destruction to cosmetics series can be reduced; and can effectively protect the effective ingredient of Margarita not destroyed by other components in cosmetics; and the active substance of Margarita can be carried to the deep skin of human body by this hydrolyzed pearl powder flexible nano-liposomes; improve bioavailability, reach better aesthetic health care effect.
Oleum Hippophae is the complex of multivitamin and bioactive substance.Its VC content occupy one cut fruit, first of vegetable, it is described as " king of VC ", VC is kind of a natural internal whitening agent, can effectively suppress the deposition of abnormal pigment on skin and the activity of tryrosinase, and help the reduction of dopachrome (tyrosine transforms into melanic intermediate), formed thus reducing melanin, effectively clean white muscle skin, and collagenation in epithelial tissue can be promoted, increase the immunologic function of skin；Contained VE can eliminate free radical and resist Oxidation, keeps the unsaturated fatty acid in cell not oxidized when light, heat radiation；Contained carotene can be converted into VA, and then eliminates epithelial tissue keratinization or abnormal rough.Its multivitamin contained and multiple unsaturated fatty acid synergism, re-epithelilization can be promoted, it is obviously improved skin epidermal cells circulatory function, repairs skin and promote the microcirculation of capillary of skin, it is suppressed that the carrying out of lipid peroxidation, improve metabolism, delay skin aging process, can keep the sour environment of skin, has the effect of antiallergic, bactericidal antiphlogistic, and there is stronger saturating property, it is a kind of desirably natural skin care product raw material.
Summary of the invention
For overcoming the shortcoming existing for prior art, it is an object of the invention to provide a kind of Oleum Hippophae moisturizing containing hydrolyzed pearl powder flexible nano-liposomes and repair breast, it is with liposome for carrier, nutritional labeling is carried to deep skin, utilization is fully absorbed by human body, these skin care item can solve the problem that skin is intensely dark, flexibility decrease, dry aging problem, and moisturizing repairing effect is good.
For realizing described goal of the invention, breast is repaired in Oleum Hippophae moisturizing provided by the invention, it is made up of by weight percentage following component: hydrolyzed pearl powder flexible nano-liposomes 2-15%, Oleum Hippophae 5-15%, hyaluronic acid 0.2-2%, emulsifying agent 5-20%, wetting agent 10-20%, stabilizer 1-20%, surplus is deionized water, and the percentage composition sum of each component is 100%.
Described hydrolyzed pearl powder flexible nano-liposomes, mainly contains soybean lecithin, sodium cholate, hydrolyzed pearl powder, and particle diameter is at 10nm-100nm.
One or more in PEG40 stearate, PEG60 castor oil hydrogenated, Tween 80, Polyethylene Glycol (300) monoleate, Macrogol 4000, branched fatty acid ester and Fatty acid macrogolglycerides of described emulsifying agent.
Described wetting agent is one or more in vaseline and lanoline.
Described stabilizer is one or more in glycerol, spermol (cetyl alcohol), propylene glycol and butanediol.
The preparation method that it is a further object to provide described hydrolyzed pearl powder flexible nano-liposomes, is realized by following steps:
(1) quantitatively weigh fabaceous lecithin, sodium cholate, hydrolyzed pearl powder are dissolved in chloroform；
(2) water-bath 37.5 DEG C, chloroform removed under pressure；
(3) evacuation preserves 5h；
(4) add isotonic phosphate buffer liquid (pH7.4), Rotary Evaporators rotates after hydration 1h again and removes organic solvent, form hydrolyzed pearl powder flexible lipidosome suspension；
(5) liposome turbid liquor is placed in ice-water bath and is interrupted after ultrasonic 30min through probe-type, after filtering with 0.2 μm of filter, obtain hydrolyzed pearl powder flexible nano-liposomes.
It is also another object of the present invention to provide the preparation method that breast is repaired in the described Oleum Hippophae moisturizing containing hydrolyzed pearl powder flexible nano-liposomes, realized by following steps:
(1) weighing Oleum Hippophae and the oil phase dispensing such as emulsifying agent, wetting agent of formula ratio, stirring mixes, and heating obtains homogeneous oil phase compound to 75-85 DEG C；
(2) weighing stabilizer and the deionized water of formula ratio, heating is to 75-85 DEG C, and mix homogeneously obtains aqueous phase compound；
(3) oil phase compound is added in whipping process aqueous phase compound, emulsifying it；
(4), after being cooled to 50 DEG C, hydrolyzed pearl powder flexible nano-liposomes, hyaluronic acid are added, homogeneous；
(5) being cooled to 35 DEG C, finished product is packed to obtain in discharging.
The present invention utilizes the several amino acids contained in hydrolyzed pearl powder and the nutrient substance such as trace element, polypeptide, prepares Oleum Hippophae moisturizing and repairs breast, can effectively strengthen the metabolism of skin epidermal cells and corium, repair the function of skin.Flexible nano-liposomes average diameter is 100 nanometers, is the 1/200～1/300 of human body cell diameter, can penetrate human body skin top layer easily, makes Margarita powder and cell fusion, plays effect；Be aided with there is the Oleum Hippophae of stronger moisturizing repair, hyaluronic acid acts on skin, can go deep into humidifying keratinocyte and powerful hydration to improve the elasticity of dermis of skin, strengthen skin resistance, compact skin, desalinates microgroove.Product of the present invention is natural, gentle, almost without stimulation, it is possible to the long-term use for skin barrier reparation, skin moistening moisturizing and skin rejuvenation.Dry skin quality, sensitive skin quality etc. are had good replenishing water and preserving moisture repairing effect, and can effectively clean white muscle skin, crease-resistant anti-aging.
Detailed description of the invention
Below in conjunction with detailed description of the invention, principles of the invention and feature being described, example is served only for explaining the present invention, is not intended to limit the scope of the present invention.
Embodiment 1
Hydrolyzed pearl powder flexible nano-liposomes forms:
Soybean lecithin 5.5wt%
Sodium cholate 1.5wt%
Hydrolyzed pearl powder 1.5wt%.
The preparation method of hydrolyzed pearl powder flexible nano-liposomes, is realized by following steps:
(1) quantitatively weigh fabaceous lecithin, sodium cholate, hydrolyzed pearl powder are dissolved in chloroform；
(2) water-bath 37.5 DEG C, chloroform removed under pressure；
(3) evacuation preserves 5h；
(4) add isotonic phosphate buffer liquid (pH7.4), Rotary Evaporators rotates after hydration 1h again and removes organic solvent, form hydrolyzed pearl powder flexible lipidosome suspension；
(5) liposome turbid liquor is placed in ice-water bath and is interrupted after ultrasonic 30min through probe-type, after filtering with 0.2 μm of filter, obtain hydrolyzed pearl powder flexible nano-liposomes.
Breast is repaired in Oleum Hippophae moisturizing containing hydrolyzed pearl powder flexible nano-liposomes
Oil phase composition:
The stirring of above-mentioned oil phase dispensing being mixed, heating obtains homogeneous oil phase compound to 75 DEG C；In whipping process, add the deionized water of 60wt%75 DEG C, mix homogeneously, emulsifying it, after being cooled to 50 DEG C, add 4wt% hydrolyzed pearl powder flexible nano-liposomes (embodiment 1) and 0.2wt% hyaluronic acid, homogeneous, being cooled to 35 DEG C, finished product is packed to obtain in discharging.
Embodiment 2
Oil phase composition:
Oleum Hippophae 15wt%
Tween 80 10wt%
Vaseline 10wt%
The stirring of above-mentioned oil phase dispensing being mixed, heating obtains homogeneous oil phase compound to 75 DEG C；In whipping process, add the deionized water of 10wt% glycerol and 42wt%75 DEG C, mix homogeneously, emulsifying it, after being cooled to 50 DEG C, add 13wt% hydrolyzed pearl powder flexible nano-liposomes (embodiment 1) and 0.2wt% hyaluronic acid, homogeneous, being cooled to 35 DEG C, finished product is packed to obtain in discharging.
Describe the component of the present invention, preparation method and the effect reached above in association with embodiment in detail, but embodiment illustrates the present invention with being only for demonstration.Description is only for explaining claims.But protection scope of the present invention is not limited to description.Any those familiar with the art in the technical scope of present disclosure, the change that can readily occur in or replacement, all should be encompassed within protection scope of the present invention.
Embodiment 3 effect detection
Being participated in using moisturizing of the present invention to repair breast from the women of the various skin types of 20 to 60 years old by 80 ages, every women is previously every average daily uses that there is prestige or at least one natural or organic skin care products of medicine cosmetic board.Wherein 50 participants are sensitive skin, are defined as presently, there are such as flushing heating, tight sense, desquamation or acneform lesion.Participant's morning and evening every day face after the cleaning uses the present composition, substitutes conventional skin-protection product.After using surrounding, participant completes questionnaire.Result of study is in Table 1.
Table 1
Participant all admits this product to no skin irritation, substantially feels skin comfort, softness after using, and without greasy feeling, has obvious sun-proof whitening effect, and sunburn is had good reparation effect, reduces the skin lesion cicatrix of acne.
Embodiment 4 effect detection
Test is divided into invention group, matched group and blank group, and invention group uses embodiment 1 to prepare the skin care item of gained.
Oleum Hippophae in the skin moistening product of the matched group plant society oils and fats without embodiment 1, other component, content and preparation method thereof are identical with embodiment 1.
The skin moistening product of blank group are without the Oleum Hippophae in embodiment 1 and hyaluronic acid, and other component, content and preparation method thereof are identical with embodiment 1.
Randomly select 90 bit test persons, be randomly divided into 3 groups, often organize 30 people, test at December.3 groups be divided into smear the skin moistening product of invention group, matched group and blank group respectively, and every day respectively smears once sooner or later, after using surrounding, observe respectively and often organize in tester for the obvious number of the efficiently individual quantity preventing xerosis cutis from chapping and effect, and result is referring to table 2.
Table 2 prevents xerosis cutis from chapping measure of merit result
| Efficiently individual quantity | The obvious number of effect | Effective percentage | The obvious rate of effect | |
| Blank group | 6 | 1 | 20% | 3.33% |
| Matched group | 18 | 14 | 60% | 46.67% |
| Invention group | 27 | 21 | 90% | 70% |
Be can be seen that by upper table 2, skin moistening product of the present invention contain Oleum Hippophae and the hyaluronic acid of special ratios simultaneously, interact between the two collaborative, with containing only having in Oleum Hippophae and hyaluronic acid compared with any one matched group, the skin moistening product of invention group are chapped the raising of highly significant to preventing xerosis cutis.
Claims (7)
1. breast is repaired in the Oleum Hippophae moisturizing containing hydrolyzed pearl powder flexible nano-liposomes, it is characterized in that, it is made up of by weight percentage following component: hydrolyzed pearl powder flexible nano-liposomes 2-15%, Oleum Hippophae 5-15%, hyaluronic acid 0.2-2%, emulsifying agent 5-20%, wetting agent 10-20%, stabilizer 1-20%, surplus is deionized water, and the percentage composition sum of each component is 100%.
2. breast is repaired in a kind of Oleum Hippophae moisturizing containing hydrolyzed pearl powder flexible nano-liposomes according to claim 1, it is characterized in that, described hydrolyzed pearl powder flexible nano-liposomes, is made up of soybean lecithin, sodium cholate, hydrolyzed pearl powder, and particle diameter is at 10nm-100nm.
3. breast is repaired in a kind of Oleum Hippophae moisturizing containing hydrolyzed pearl powder flexible nano-liposomes according to claim 1, it is characterized in that, one or more in PEG40 stearate, PEG60 castor oil hydrogenated, Tween 80, Polyethylene Glycol (300) monoleate, Macrogol 4000, branched fatty acid ester and Fatty acid macrogolglycerides of described emulsifying agent.
4. breast is repaired in a kind of Oleum Hippophae moisturizing containing hydrolyzed pearl powder flexible nano-liposomes according to claim 1, it is characterised in that described wetting agent is one or more in vaseline and lanoline.
5. breast is repaired in a kind of Oleum Hippophae moisturizing containing hydrolyzed pearl powder flexible nano-liposomes according to claim 1, it is characterised in that described stabilizer is one or more in glycerol, spermol, propylene glycol and butanediol.
6. breast is repaired in a kind of Oleum Hippophae moisturizing containing hydrolyzed pearl powder flexible nano-liposomes according to claim 1 and 2, it is characterised in that described hydrolyzed pearl powder flexible nano-liposomes is prepared by method and obtains:
(1) quantitatively weigh fabaceous lecithin, sodium cholate, hydrolyzed pearl powder are dissolved in chloroform；
(2) water-bath 37.5 DEG C, chloroform removed under pressure；
(3) evacuation preserves 5h；
(4) add the isotonic phosphate buffer liquid of pH7.4, Rotary Evaporators rotates after hydration 1h again and removes organic solvent, form hydrolyzed pearl powder flexible lipidosome suspension；
(5) liposome turbid liquor is placed in ice-water bath and is interrupted after ultrasonic 30min through probe-type, after filtering with 0.2 μm of filter, obtain hydrolyzed pearl powder flexible nano-liposomes.
7. the preparation method that breast is repaired in a kind of Oleum Hippophae moisturizing containing hydrolyzed pearl powder flexible nano-liposomes described in claim 1, it is characterised in that realized by following steps:
(1) taking oil phase dispensing Oleum Hippophae and emulsifying agent, wetting agent, stirring mixing, heating obtains homogeneous oil phase compound to 75-85 DEG C；
(2) taking stabilizer and deionized water, heating is to 75-85 DEG C, and mix homogeneously obtains aqueous phase compound；
(3) oil phase compound is added in whipping process aqueous phase compound, emulsifying；
(4), after being cooled to 50 DEG C, hydrolyzed pearl powder flexible nano-liposomes, hyaluronic acid are added, homogeneous；
(5) being cooled to 35 DEG C, finished product is packed to obtain in discharging.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610162513.1A CN105796461A (en) | 2016-03-21 | 2016-03-21 | Moisturizing and repairing lotion containing hydrolyzed pearl essence flexible nano-liposomes and sea buckthron oil |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610162513.1A CN105796461A (en) | 2016-03-21 | 2016-03-21 | Moisturizing and repairing lotion containing hydrolyzed pearl essence flexible nano-liposomes and sea buckthron oil |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105796461A true CN105796461A (en) | 2016-07-27 |
Family
ID=56454131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610162513.1A Pending CN105796461A (en) | 2016-03-21 | 2016-03-21 | Moisturizing and repairing lotion containing hydrolyzed pearl essence flexible nano-liposomes and sea buckthron oil |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105796461A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106913588A (en) * | 2017-03-27 | 2017-07-04 | 北海市宝珠林海洋科技有限公司 | A kind of externally applied drug of the infantile eczema of treated powder containing pearl |
| CN106924163A (en) * | 2017-03-27 | 2017-07-07 | 北海市宝珠林海洋科技有限公司 | A kind of reparation liquid containing hydrolysis pearl composition |
| CN113143792A (en) * | 2021-03-23 | 2021-07-23 | 杭州帝通生物科技有限公司 | Moisturizing repair cream for repairing skin barrier and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1795874A (en) * | 2004-12-28 | 2006-07-05 | 海南京润珍珠生物技术有限公司 | Method for preparing liposome of pearl digest |
| CN101278894A (en) * | 2008-05-23 | 2008-10-08 | 海南京润珍珠生物技术股份有限公司 | A sunscreen containing pearl hydrolyzate liposome components |
| CN101288640A (en) * | 2008-05-23 | 2008-10-22 | 海南京润珍珠生物技术股份有限公司 | An acne-removing essence added with pearl hydrolyzate liposome |
| CN101697956A (en) * | 2009-10-19 | 2010-04-28 | 海南京润珍珠生物技术股份有限公司 | Anti-acne jelly with pearl hydrolyzate liposome |
| CN101697954A (en) * | 2009-10-19 | 2010-04-28 | 海南京润珍珠生物技术股份有限公司 | Anti-wrinkle emulsion with pearl hydrolyzate liposome |
-
2016
- 2016-03-21 CN CN201610162513.1A patent/CN105796461A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1795874A (en) * | 2004-12-28 | 2006-07-05 | 海南京润珍珠生物技术有限公司 | Method for preparing liposome of pearl digest |
| CN101278894A (en) * | 2008-05-23 | 2008-10-08 | 海南京润珍珠生物技术股份有限公司 | A sunscreen containing pearl hydrolyzate liposome components |
| CN101288640A (en) * | 2008-05-23 | 2008-10-22 | 海南京润珍珠生物技术股份有限公司 | An acne-removing essence added with pearl hydrolyzate liposome |
| CN101697956A (en) * | 2009-10-19 | 2010-04-28 | 海南京润珍珠生物技术股份有限公司 | Anti-acne jelly with pearl hydrolyzate liposome |
| CN101697954A (en) * | 2009-10-19 | 2010-04-28 | 海南京润珍珠生物技术股份有限公司 | Anti-wrinkle emulsion with pearl hydrolyzate liposome |
Non-Patent Citations (2)
| Title |
|---|
| 孟胜男等主编: "《药剂学》", 31 January 2016, 中国医药科技出版社 * |
| 张彰等编著: "《日用化学品》", 31 January 2015, 中国石化出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106913588A (en) * | 2017-03-27 | 2017-07-04 | 北海市宝珠林海洋科技有限公司 | A kind of externally applied drug of the infantile eczema of treated powder containing pearl |
| CN106924163A (en) * | 2017-03-27 | 2017-07-07 | 北海市宝珠林海洋科技有限公司 | A kind of reparation liquid containing hydrolysis pearl composition |
| CN113143792A (en) * | 2021-03-23 | 2021-07-23 | 杭州帝通生物科技有限公司 | Moisturizing repair cream for repairing skin barrier and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1761450B (en) | Skin external preparation characterized by containing saccharide derivative of alpha, alpha-trehalose | |
| RU2537235C2 (en) | Mildly acting indelible compositions for skin care | |
| EP1069886B1 (en) | Use of a topical formulation of the oil-in-water type, comprising galactolipid material as emulsifier, for providing a prolonged effect of an incorporated active substance | |
| TW201924701A (en) | Method and topical composition for modification of a skin microbiome | |
| CN109498478A (en) | A kind of fullerene external use composition | |
| CN103816165B (en) | A kind of composition for treating acne | |
| CN117045523A (en) | High-content azelaic acid composition and preparation method thereof | |
| CN105796459A (en) | Moisturizing gel containing hydrolyzed pearl powder flexible nano liposome | |
| KR20090041886A (en) | Vegetable triple moisturizing component and skin care composition comprising the same | |
| JP2010163418A (en) | Cosmetic | |
| JP2010522757A (en) | Treatment of mammalian skin with skin emollient fungicide | |
| KR20200073970A (en) | Soothing cream and manufacturing method for the same | |
| KR102078667B1 (en) | Cosmetic composition containg nanoemulsion encapsulated with 7-dehydrocholesterol, cholesterol and stearic acid in inner phase of hyaluronate-ceramide NP complex and manufacturing method thereof | |
| KR101605517B1 (en) | Manufacturing method for cosmetic composition for improving acne and cosmetic compostion thereof | |
| CN116407486B (en) | Active composition, cosmetic composition, application of active composition, repairing essence and preparation method of repairing essence | |
| CN105796461A (en) | Moisturizing and repairing lotion containing hydrolyzed pearl essence flexible nano-liposomes and sea buckthron oil | |
| US20050063930A1 (en) | Topical formulation of the oil-in-water type, comprising galactolipid material as emulsifier, with a prolonged effect of an incorporated active substance | |
| CN1357321A (en) | Inflammation and red spot reducing method | |
| KR101460777B1 (en) | Cosmetic composition for improving acne | |
| US20010014343A1 (en) | Skin care composition | |
| JP2006028026A (en) | Hair-growing agent | |
| JP2007291062A (en) | Formulation for basic cosmetics and basic cosmetics | |
| US20060222689A1 (en) | Skin care compositions and methods | |
| JP5025254B2 (en) | Cosmetic preparations and cosmetics for improving the skin groove density | |
| CN105919886A (en) | Quick-acting wrinkle repairing emulsion and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160727 |