CN1056064C - Medicine for treating liver cancer and its preparing process - Google Patents
Medicine for treating liver cancer and its preparing process Download PDFInfo
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- CN1056064C CN1056064C CN93110434A CN93110434A CN1056064C CN 1056064 C CN1056064 C CN 1056064C CN 93110434 A CN93110434 A CN 93110434A CN 93110434 A CN93110434 A CN 93110434A CN 1056064 C CN1056064 C CN 1056064C
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- radix
- rhizoma
- chinese medicine
- traditional chinese
- herba
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- 239000003814 drug Substances 0.000 title claims abstract description 22
- 238000000034 method Methods 0.000 title claims description 5
- 201000007270 liver cancer Diseases 0.000 title abstract description 6
- 208000014018 liver neoplasm Diseases 0.000 title abstract description 5
- 229940079593 drug Drugs 0.000 title description 3
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- 239000009636 Huang Qi Substances 0.000 claims abstract description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 17
- 239000000843 powder Substances 0.000 claims description 6
- 239000000341 volatile oil Substances 0.000 claims description 5
- 241000756943 Codonopsis Species 0.000 claims description 3
- 241001489978 Eupolyphaga Species 0.000 claims description 3
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 3
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- 235000020357 syrup Nutrition 0.000 abstract description 2
- 239000003826 tablet Substances 0.000 abstract description 2
- 241000722953 Akebia Species 0.000 abstract 1
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- 235000003416 Dioscorea oppositifolia Nutrition 0.000 abstract 1
- 240000000233 Melia azedarach Species 0.000 abstract 1
- GXCLVBGFBYZDAG-UHFFFAOYSA-N N-[2-(1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine Chemical compound CN(CCC1=CNC2=C1C=CC=C2)CC=C GXCLVBGFBYZDAG-UHFFFAOYSA-N 0.000 abstract 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a traditional Chinese medicine for treating liver cancer and a preparation method thereof, the traditional Chinese medicine formula comprises radix codonopsitis, radix astragali, herba scutellariae barbatae, turtle shell, tuckahoe, radix bupleuri, oyster, peach kernel, ground beeltle, raw rhubarb, sappan wood, akebia stem, radix curcumae, rhizoma atractylodis macrocephalae, agilawood and other components, and the traditional Chinese medicine formula also can comprise manyleaf paris rhizome, oriental wormwood, rhizoma cyperi, dried orange peel, herba patriniae, semen coicis, Chinese yam, safflower, herba lycopi, caulis spatholobi, medicated leaven, malt, kelp, rhizoma sparganii, szechwan chinaberry fruit, rhizoma. The Chinese medicinal formulation can be made into tablet, pill, capsule, oral liquid, syrup, etc. The traditional Chinese medicine is superior to radiotherapy, chemotherapy and other traditional Chinese medicine preparations, has certain inhibition effect on tumor, and can effectively relieve clinical symptoms.
Description
The present invention relates to a kind of medicine and manufacture method thereof for the treatment of hepatocarcinoma.
Primary hepatocarcinoma is one of common cancer, has belonged to middle and advanced stage when having the patient of 80-90% to go to a doctor, and survival rate is extremely short, and mortality rate is high.Its treatment is that current medical circle is felt one of stubborn problem most.General X-ray therapy, chemotherapy, the effect that adopts is all undesirable, and serious side effects is arranged, existing treatment by Chinese herbs is a starting point to attack heresy merely all, objective curative effect is still undesirable, China's soup is encouraged the formal plan professor and once reported 54 routine Chinese medicine groups in " Primary Liver Cancer ChinaAcad Bejing Springer-Verlag Berlin 1,989 487 " literary composition, and 61 routine chemotherapy group, 34 routine combination radiotherapy group are controlled back one annual survival rate and are respectively 5.8%, 2.1%, 14.7%.
The object of the present invention is to provide a kind of a kind of Chinese medicine and manufacture method thereof for the treatment of hepatocarcinoma that human body is had no side effect, during this Chinese medicine can prolong effectively, advanced liver cancer patient's survival rate, suppress the development of tumor; Alleviate the clinical symptoms of hepatocarcinoma patient; Improve overall health of patients.
The object of the present invention is achieved like this:
Comprise Radix Codonopsis 2～8 weight %, the Radix Astragali 2～8 weight %, Herba Scutellariae Barbatae 2～8 weight %, Carapax Trionycis 0.5～4 weight %, Poria 2～8 weight %, Radix Bupleuri 1～4 weight %, Concha Ostreae 2～8 weight %, Semen Persicae 1～5 weight %, Eupolyphaga Seu Steleophaga 1～4 weight %, Radix Et Rhizoma Rhei 1～5 weight %, Lignum Sappan 2～8%, Caulis Akebiae 2～8%, Radix Curcumae 2～8 weight %, the Rhizoma Atractylodis Macrocephalae 2～8 weight %, Lignum Aquilariae Resinatum 0.5～4 weight % in this Chinese medicine preparation.
Can also comprise Rhizoma Paridis 0～8 weight %, Herba Artemisiae Scopariae 0～8 weight %, Rhizoma Cyperi 0～8 weight %, Pericarpium Citri Reticulatae 0～8 weight %, Herba Patriniae 0～8 weight %, Semen Coicis 0～8 weight % in this Chinese medicine preparation.
Can also comprise Rhizomadioscoreae 0～8 weight %, Flos Carthami 0～8 weight %, Herba Lycopi 0～8 weight %, Caulis Spatholobi 0～8 weight %, Massa Medicata Fermentata 0～8 weight %, Fructus Hordei Germinatus 0～8 weight %, Thallus Laminariae (Thallus Eckloniae) 0～8 weight %, Rhizoma Paridis 0～8 weight %, Radix Angelicae Sinensis 0～8 weight % in this Chinese medicine preparation.
It is blood stasis, the insufficiency of the spleen and viewpoint of seeing that this prescription has been taken into account hepatocarcinoma, sets upright and combines to attack heresy, and full side is long memorial liver spleen, softening hardness and resolving stasis altogether, the merit of heat-clearing and toxic substances removing.
The preparation method of this medicine is for to make coarse powder with Lignum Aquilariae Resinatum, and half extracts volatile oil, and half is ground into 100 order fine powders, and all the other each medicines decoct with water secondary, and collecting decoction filters, and filter is crossed and is concentrated into relative density 1.1g/cm
3, add the ethanol mix homogeneously.Make and mix liquid measure and contain alcohol and reach 50% and left standstill 24 hours, get supernatant and reclaim ethanol, be condensed into relative density 1.3g/cm
3Above thick paste adds the Lignum Aquilariae Resinatum fine powder, mixes, and oven drying at low temperature is pulverized, alcohol granulation, and oven dry is treated coldly, and spray adds Lignum Aquilariae Resinatum volatile oil, is pressed into tablet or pill, and sugar coating is promptly.
This Chinese medicine can also be made hydration dosage form, syrup preparation, capsule formulation.
Chinese medicine of the present invention is taken and controlled observation through clinical 164 people, and learns by statistics and handle, and proves to be better than X-ray therapy, chemotherapy of using at present and the various Chinese medicine preparation of in the past reporting, and one annual survival rate 328% is significantly higher than other therapies.And proof has certain inhibitory action to tumor, oral tablet 136～150g/l＜g, 10～12 days is 31.74～34.13% to the hepatocarcinoma suppression ratio, tumor body coefficient of stabilization is 78.7%, can effectively alleviate the clinical symptoms of liver cancer patient, its pain relief rate is 76.3%, poor appetite improvement rate is 80.5%, and diarrhoea loose stool remission rate is 66.7%; The animation enhancer reaches 93%.Prove that through toxicity test this medicine can be taken for a long time to human body avirulence, safety.
Embodiment:
Radix Codonopsis 800g, Radix Astragali 1000g, Herba Scutellariae Barbatae 1000g, Semen Persicae 500g, Poria 800g, Eupolyphaga Seu Steleophaga 200g, Radix Bupleuri 400g, Concha Ostreae 600g, Semen Persicae 300g, Carapax Trionycis 200g, Radix Et Rhizoma Rhei 100g, Lignum Sappan 1000g, Caulis Akebiae 1000g, Radix Curcumae 800g, Rhizoma Atractylodis macrocephalae 1000g, Lignum Aquilariae Resinatum 200g, Rhizoma Paridis 800g, Rhizoma Cyperi 800g, Herba Artemisiae Scopariae 800g, Pericarpium Citri Reticulatae 1000g, Herba Patriniae 800g, Radix Angelicae Sinensis 500g.
Lignum Aquilariae Resinatum is made coarse powder, half extracts volatile oil, second half is ground into 100 order fine powders again, and all the other each medicinal decoctings boil secondary, and collecting decoction filters, filtrate is concentrated into relative density 1.1g/cm, add the ethanol mix homogeneously makes mixed liquor contain the alcohol amount to reach 50%, left standstill 24 hours, and got supernatant recovery ethanol and be condensed into relative density 1.3g/cm, above thick paste, add Lignum Aquilariae Resinatum volatile oil, compacting is in blocks, and sugar coating promptly.
Claims (2)
1. a medicine for the treatment of hepatocarcinoma is characterized in that being made by following raw material and percentage by weight: Radix Codonopsis 2-8, Radix Astragali 2-8, Herba Scutellariae Barbatae 2-8, Carapax Trionycis 0.5-4, Poria 2-8, Radix Bupleuri 1-4, Concha Ostreae 2-8, Semen Persicae 1-5, Eupolyphaga Seu Steleophaga 1-4, Radix Et Rhizoma Rhei 1-5, Lignum Sappan 2-8, Caulis Akebiae 2-8, Radix Curcumae 2-8, Rhizoma Atractylodis Macrocephalae 2-8, Lignum Aquilariae Resinatum 0.5-4, Rhizoma Paridis 0-8, Rhizoma Cyperi 0-8, Herba Artemisiae Scopariae 0-8, Pericarpium Citri Reticulatae 0-8, Herba Patriniae 0-8.
2. the manufacture method of medicine according to claim 1, it is characterized in that: except that Lignum Aquilariae Resinatum, all the other each medicinal decoctings boil secondary, and collecting decoction filters, and filtrate is concentrated into relative density 1.1g/cm
3, add the ethanol mix homogeneously, make mixed liquor contain the alcohol amount and reach 50%, left standstill 24 hours, get supernatant and reclaim ethanol, be condensed into relative density 1.3g/cm
3About thick paste, add half fine powder of Lignum Aquilariae Resinatum consumption, mix, oven drying at low temperature is pulverized, alcohol granulation, dries, treats that cold, spray adds second half the volatile oil that extracts in advance of Lignum Aquilariae Resinatum consumption, is compressed to finished product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93110434A CN1056064C (en) | 1993-01-20 | 1993-01-20 | Medicine for treating liver cancer and its preparing process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93110434A CN1056064C (en) | 1993-01-20 | 1993-01-20 | Medicine for treating liver cancer and its preparing process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1075886A CN1075886A (en) | 1993-09-08 |
| CN1056064C true CN1056064C (en) | 2000-09-06 |
Family
ID=4988304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN93110434A Expired - Fee Related CN1056064C (en) | 1993-01-20 | 1993-01-20 | Medicine for treating liver cancer and its preparing process |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1056064C (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1054747C (en) * | 1994-02-05 | 2000-07-26 | 马新生 | Anti-cancer capsule |
| CN1048409C (en) * | 1994-11-22 | 2000-01-19 | 王志义 | Capsule for protecting liver and eliminating tumor |
| CN1059574C (en) * | 1996-09-03 | 2000-12-20 | 张文义 | Chinese medicine preparation |
| CN1079250C (en) * | 1998-03-24 | 2002-02-20 | 王光辉 | Chinese medicinal prescription for treating liver cancer |
| CN100457093C (en) * | 2004-11-12 | 2009-02-04 | 潘求谛 | Chinese medicinal preparation for treating liver cancer, hepatitis B cirrhosis and preventing liver fibrillation and preparation thereof |
| CN101099850B (en) * | 2007-07-20 | 2010-06-16 | 北京亚东生物制药有限公司 | Medicine composition for treating chronic active hepatitis and early-stage hepatocirrhosis and preparation method thereof |
| CN104147452A (en) * | 2014-08-19 | 2014-11-19 | 陈学波 | Medicine for treating mid-late stage liver cancer |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1057399A (en) * | 1990-06-18 | 1992-01-01 | 李文升 | A kind of manufacture method of Chinese medicine atomic powder for clearing lump in abdomen |
-
1993
- 1993-01-20 CN CN93110434A patent/CN1056064C/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1057399A (en) * | 1990-06-18 | 1992-01-01 | 李文升 | A kind of manufacture method of Chinese medicine atomic powder for clearing lump in abdomen |
Non-Patent Citations (1)
| Title |
|---|
| 《上海中医药杂志》1985年第11期 1985.11.30 潘敏求等，60例原支性肝癌临床疗效观察 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1075886A (en) | 1993-09-08 |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |