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CN105381177A - External use traditional Chinese medicine for treating sweet stains - Google Patents

External use traditional Chinese medicine for treating sweet stains Download PDF

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Publication number
CN105381177A
CN105381177A CN201510999726.5A CN201510999726A CN105381177A CN 105381177 A CN105381177 A CN 105381177A CN 201510999726 A CN201510999726 A CN 201510999726A CN 105381177 A CN105381177 A CN 105381177A
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parts
chinese medicine
stains
traditional chinese
external use
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CN201510999726.5A
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潘剑崎
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/36—Arsenic; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/646—Arachnids, e.g. spiders, scorpions, ticks or mites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/648—Myriapods, e.g. centipedes or millipedes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/19—Acanthaceae (Acanthus family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/533—Leonurus (motherwort)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/754—Evodia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
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  • Engineering & Computer Science (AREA)
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  • Insects & Arthropods (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
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  • Medicines Containing Plant Substances (AREA)
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Abstract

The invention relates to an external use traditional Chinese medicine for treating sweet stains. The external use traditional Chinese medicine for treating sweet stains is prepared from 0.2 part of realgar, 5 parts of motherwort, 3 parts of whole scorpion, 3 parts of centipede, 5 parts of fistular onion stalks, 2 parts of sculellaria barbata, 10 parts of paniculate swallowwort roots, 12 parts of polygonum cuspidatum, 5 parts of radix ampelopsis, 6 parts of andrographis paniculata, 3 parts of evodia rutaecarpa and 3 parts of dried tangerine or orange peel according to a certain weight ratio. Clinical experiments prove that the external use traditional Chinese medicine can safely and effectively treat sweet stains.

Description

A kind of external application Chinese medicine for the treatment of tinea versicolor
Technical field
The present invention relates to a kind of Chinese medicine, especially relate to a kind of external application Chinese medicine for the treatment of tinea versicolor.
Background technology
Tinea versicolor is a kind of chronic superficial mycosis caused by Pityrosporum ovale, is commonly called as " tinea versicolor ".This disease is apt to occur in the position of hyperhidrosis, as trunk, axillary fossa, groin, thigh and neck surface, often shows as Xia Fadong light, lasting for years.The Symptoms of tinea versicolor is: skin lesion is Semen Glycines size macule, NIP, or gently itches, and above covers superfine micro-shinny squama, and in color of the leather, lark or sepia arrange black, removes squama, in depigmentation macule.
At present the effective medicine of generally recognized as safe is still lacked at present for tinea versicolor.
Involved by external application Chinese medicine of the present invention, the present Research of medical material is as follows:
Realgar
[source] is the Ore of sulfide-based mineral Realgar.
[function cures mainly] dampness, dispels the wind, parasite killing, removing toxic substances.Control scabies.
Herba Leonuri
[source] this product is the fresh or dry aerial parts of labiate Herba Leonuri LeonurusjaponicusHoutt..
[function cures mainly] invigorates blood circulation, blood stasis dispelling, regulating menstruation, and disappear water.
Scorpio
[source] this product is the dry body of Buthidae animal Scorpio ButhusmartensiiKarsch.
[function cures mainly] endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.
Scolopendra
[source] this product is the dry body of Scolopendridae animal Scolopendpa Subspinipes Mutilans L. KOCH ScolopendrasubspinipesmutilansL.Koch.
[function cures mainly] endogenous wind stopping spasmolytic, merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain.
Bulbus Allii Fistulosi
[source] this product is Liliaceae allium Herba Alii fistulosi AlliumfistulosumL., with bulb or all herbal medicine.
[function cures mainly] delivers, and activates yang, removing toxic substances.
Herba Scutellariae Barbatae
[source] this product is the dry herb of labiate Herba Scutellariae Barbatae ScutellariabarbataDon [S.rivularisWall].
[function cures mainly] heat clearing away, removing toxic substances, dissipating blood stasis, hemostasis, analgesic therapy.
Radix Cynanchi Paniculati
[source] this product is asclepiadaceae Cynanchum plant Radix Cynanchi Paniculati Cynanchumpaniculatum(Bge.) the dry root and rhizome of Kitag..
[function cures mainly] dispels the wind removing dampness, antalgesic-antipruritic.
Rhizoma Polygoni Cuspidati
[source] this product is polygonaceae plant Rhizoma Polygoni Cuspidati PolygonumcuspidatumSieb.etZucc., dry rhizome and root.
[function cures mainly] expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.
Radix Ampelopsis
[source] this product is vitaceae Radix Ampelopsis Ampelopsisjaponica(Thunb.) dried root of Makino.
[function cures mainly] heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.
Herba Andrographis
[source] this product is acanthaceous plant Herba Andrographis (circular cone must medicinal herbs) Andrographispaniculata(Burm.f.) dry aerial parts of Nees.
[function cures mainly] heat-clearing and toxic substances removing, removing heat from blood, detumescence.
Fructus Evodiae
[source] is the immature fruit of rutaceae Fructus Evodiae.
[function cures mainly] warming middle-JIAO, pain relieving, regulates the flow of vital energy, and dampness controls eczema, impetigo.
Pericarpium Citri Reticulatae
[source] this product is the dry mature skin of rutaceae orange CitrusreticulataBlanco and variety thereof.
[function cures mainly] regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.
Summary of the invention
The present invention aims to provide a kind of external application Chinese medicine for the treatment of tinea versicolor, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing tinea versicolor.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of external application Chinese medicine for the treatment of tinea versicolor, it is characterized by, make unguentum by the raw material of following parts by weight: Realgar 0.2 part, Herba Leonuri 5 parts, Scorpio 3 parts, Scolopendra 3 parts, Bulbus Allii Fistulosi 5 parts, Herba Scutellariae Barbatae 2 parts, Radix Cynanchi Paniculati 10 parts, Rhizoma Polygoni Cuspidati 12 parts, Radix Ampelopsis 5 parts, Herba Andrographis 6 parts, Fructus Evodiae 3 parts, Pericarpium Citri Reticulatae 3 parts.
Chinese medicine of the present invention is unguentum, after being cleaned up by each raw material, makes unguentum according to a conventional method, spreads on affected part outward and uses.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects the out-patient of 90 routine tinea versicolor altogether between in March ,-2015 in January, 2014, age 16-42 year, the course of disease 1 month-12 months.Be divided at random: treatment group 45 example, matched group 45 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
2, diagnostic criteria
Diagnostic criteria according to the meeting of national tinea versicolor clinical speciality:
(1) be apt to occur in breast, the back of the body, cervical region, chronic, Xia Chongdong is light, without obvious subjective symptoms, or slight pruritus when perspiring.
(2) the scaling light white macula of mottled horny layer merging or do not merge is seen.
(3) fungus microscope examination is mycelia and the spore in groups that rod-short is branched into clump.
(4) chlorine fluorescence is shown under WoodShi lamp.
3, test method
3.1 treatment groups use external-applied ointment of the present invention, external, are cleaned in affected part and dry, get appropriate ointment uniform application in affected part, and be massaged into ointment and absorb completely, every 4 hours once, within 5 days, be 1 course for the treatment of, use 2 ~ 3 courses for the treatment of continuously, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
3.2 matched groups take hundred tinea xiatare tablets, every day 3 times, each 3 ~ 5; Within 8 days, be 1 course for the treatment of, take 3 ~ 4 courses for the treatment of continuously, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
4, criterion of therapeutical effect and therapeutic outcome
4.1 criterion of therapeutical effect
With reference to State Administration of Traditional Chinese Medicine " disease of tcm Standardization of diagnosis and curative effect "
Recovery from illness: tinea versicolor symptom all disappears, skin recovers normal.
Take a turn for the better: tinea versicolor symptom alleviates, skin improvement or normal.
Invalid: tinea versicolor symptom is without being clearly better or increasing the weight of.
4.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
Group n Recovery from illness Take a turn for the better Invalid Total effective rate (%) Untoward reaction example
Treatment group 45 18（40.0%） 21（46.6%） 6（13.3%） 86.7% 0
Matched group 45 11（24.4%） 15（33.3%） 19（42.2%） 57.8% 0
For proving that the present invention has good curative effect, enumerate model case as follows:
1, gold ××, man, 37 years old, patient tells abdominal part, buttocks portion, axillary fossa is easily perspired, start this region and occur that fleck is not noted, but speckle gets more and more in the recent period, in tawny or gray shape, clear-cut margin, painless nothing is itched, sidelight sees that skin lesion surface reflection is strong, tinea versicolor is diagnosed as after examination in hospital, and give that ketoconazole is oral does not have material alterations, give external application Chinese medicine of the present invention subsequently and smear treatment, after smearing for two courses for the treatment of, above-mentioned brown spot point symptom obviously disappears to some extent, recover normal after continuing to smear two courses for the treatment of, check display no abnormality seen subsequently, so far do not recur.
2, temperature ×, man, 32 years old, main suit there will be macule summer with it, particularly evident behind, the slightly rubescent and pruritus of minority, winter disappears, and summer recurs again, goes to local hospital to be diagnosed as tinea versicolor by routine examination subsequently, hospital gives and compound recipe resorcin liniment and miconazole frost Drug therapy, and symptom is not substantive to some extent to be alleviated.After give external application Chinese medicine of the present invention and smear treatment, after smearing a course for the treatment of, tinea versicolor phenomenon takes a turn for the better to some extent, and after continuing to smear two courses for the treatment of, state of an illness rehabilitation is complete, and so far without recurring.
3, Yuan ×, female, 22 years old, main suit's physical labourer, perspire summer and how to fail again to clean health in time, appear body many places and occur that Semen Glycines is to the large small circular macule of Semen Viciae fabae, clear-cut margin, maintain an equal level with skin, surface is coated with very thin pityrosporum sample squama, local hospital is gone to be diagnosed as tinea versicolor by routine examination subsequently, hospital gives Oral Ketoconazole and treats, symptom is not alleviated to some extent, after give external application Chinese medicine of the present invention treatment, after smearing a course for the treatment of, above-mentioned macule symptom obviously takes a turn for the better to some extent, recover normal after continuing to smear two courses for the treatment of, check display no abnormality seen subsequently, so far do not recur.
Visible, the present invention adopts the formula of science and suitable proportioning, with the parasite killing that detoxifies, dispeiling pathogenic wind and removing dampness for therapeutic rules, adopts between each medicine and cooperatively interacts, synergism, and made external application Chinese medicine medicine can safe and effective treatment tinea versicolor.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: Realgar 0.2 gram, Herba Leonuri 5 grams, Scorpio 3 grams, Scolopendra 3 grams, Bulbus Allii Fistulosi 5 grams, Herba Scutellariae Barbatae 2 grams, Radix Cynanchi Paniculati 10 grams, Rhizoma Polygoni Cuspidati 12 grams, Radix Ampelopsis 5 grams, Herba Andrographis 6 grams, Fructus Evodiae 3 grams, Pericarpium Citri Reticulatae 3 grams, above-mentioned raw materials is cleaned up, put into lapping apparatus pulverization, make unguentum by Oleum sesami furnishing pasty state or other conventional methods, normal 1 day unguentum consumption must be met.
Usage and dosage: affected part is cleaned and dries, get appropriate ointment uniform application in affected part, and be massaged into ointment and absorb completely, once, be used for the treatment of tinea versicolor in every 4 hours.

Claims (1)

1. treat the external application Chinese medicine of tinea versicolor for one kind, it is characterized by, make unguentum by the raw material of following parts by weight: Realgar 0.2 part, Herba Leonuri 5 parts, Scorpio 3 parts, Scolopendra 3 parts, Bulbus Allii Fistulosi 5 parts, Herba Scutellariae Barbatae 2 parts, Radix Cynanchi Paniculati 10 parts, Rhizoma Polygoni Cuspidati 12 parts, Radix Ampelopsis 5 parts, Herba Andrographis 6 parts, Fructus Evodiae 3 parts, Pericarpium Citri Reticulatae 3 parts.
CN201510999726.5A 2015-12-28 2015-12-28 External use traditional Chinese medicine for treating sweet stains Pending CN105381177A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107823353A (en) * 2017-12-22 2018-03-23 南宁多灵生物科技有限公司 A kind of medicine for treating sweat stain

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011005749A2 (en) * 2009-07-08 2011-01-13 Onikolabs Llc Topical antifungal composition
CN103393962A (en) * 2013-07-29 2013-11-20 济南伟传信息技术有限公司 External use traditional Chinese medicine for treating tinea versicolor

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011005749A2 (en) * 2009-07-08 2011-01-13 Onikolabs Llc Topical antifungal composition
CN103393962A (en) * 2013-07-29 2013-11-20 济南伟传信息技术有限公司 External use traditional Chinese medicine for treating tinea versicolor

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107823353A (en) * 2017-12-22 2018-03-23 南宁多灵生物科技有限公司 A kind of medicine for treating sweat stain

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