CN104957135B - The purposes and ethyl oleate bactericide of ethyl oleate - Google Patents

Abstract

The invention provides a use of ethyl oleate and an ethyl oleate fungicide. The ethyl oleate is used to prepare the fungicide. The ethyl oleate bactericide is composed of ethyl oleate and conventional auxiliary materials. Wherein, the quality of ethyl oleate accounts for 0.05%-99% of the mass of the ethyl oleate fungicide, and the conventional auxiliary materials account for 1%-99.95% of the mass of the ethyl oleate fungicide. The invention provides an ethyl oleate ethyl oleate fungicide with high efficiency, no residue, low production cost, economical and practical, environment-friendly and excellent comprehensive performance.

Description

The use of ethyl oleate and ethyl oleate fungicide

technical field

The invention relates to an ethyl oleate fungicide in the technical field of pesticides and a new application of ethyl oleate.

Background technique

Plant diseases have caused huge losses to agriculture, and the average annual output of crops in the world has been reduced by about 500Mt. In history, there have been many disasters in which severe famines and even large numbers of people starved to death due to the prevalence of certain plant diseases. The use of fungicides is a cost-effective method of controlling plant diseases.

Ethyl oleate is a fatty acid ester, mainly used in the preparation of lubricants, water-resistant agents, resin tougheners, surfactants, pharmaceutical excipients, plastic plasticizers, ointment bases and other organic chemicals. Also used as a spice. At present, ethyl oleate is mainly obtained through chemical synthesis, that is, it is obtained by esterification of ethanol and oleic acid or by transesterification of another oleic acid ester and ethanol. It can also be extracted from plants. In addition, ethyl oleate acts as a pheromone in the body of bees, and the content of this substance in the body can affect and regulate the behavior of bees.

After searching the existing technical literature, it is found that there is no report on the application of ethyl oleate in the preparation of fungicides; there is no harmonious fungicide with good environmental compatibility and safety to mammals.

Contents of the invention

The present invention aims at the above-mentioned deficiencies in the prior art, and provides a use of ethyl oleate and an ethyl oleate bactericide with high efficiency, no residue, low production cost, economical and practical, environment-friendly, and excellent comprehensive performance.

The object of the invention is achieved through the following technical solutions:

The invention provides an application of ethyl oleate, that is, ethyl oleate is used in the preparation of fungicides.

The bactericide described in the present invention can be applied in the prevention and treatment of common diseases such as fruits, vegetables, wheat, rice, etc., and the specific diseases of prevention and treatment include: apple, pear, peach scab, anthracnose, brown spot, ring spot, etc.; Grape, watermelon, cucumber, powdery mildew, downy mildew, anthracnose, etc. of melon; wheat powdery mildew; rice blast, sheath blight, etc.; vegetable powdery mildew, damping off, downy mildew, anthracnose, etc.

The invention provides an ethyl oleate bactericide, which is composed of ethyl oleate (ie raw material medicine) and conventional auxiliary materials. Wherein, the quality of ethyl oleate accounts for 0.05%-99% of the mass of the ethyl oleate fungicide, and the conventional auxiliary materials account for 1%-99.95% of the mass of the ethyl oleate fungicide.

Preferably, the conventional auxiliary materials refer to one or more of solubilizers, synergists, emulsifiers, and penetrating agents.

Preferably, the solubilizer is sodium dodecylbenzenesulfonate, potassium dodecylbenzenesulfonate, polysorbate, polyethylene glycol, sorbitol polyoxyethyl ether, lignosulfonate, tea, Take one or more of all the saponins and so on.

Preferably, the emulsifier is one or more of Spans, Tweens, ethylene glycol esters, propylene glycol esters and/or polyethylene glycol-type nonionic surfactants.

Preferably, the synergist is one or more of tea saponin, polyoxyethylene ether and the like.

Preferably, the penetrating agent is azone or the like.

Weigh and weigh ethyl oleate according to the above ratio and dissolve it in a solvent, and choose to add various auxiliary materials, such as solubilizers, synergists, emulsifiers, penetrants, etc., and make various forms according to various processes. Bactericides, such as powders, emulsifiable concentrates, suspensions, dry suspensions, concentrated emulsions, sustained release agents, aqueous emulsions, sprays, etc. Wherein, the solvent can be one or more of all organic solvents such as water, ethanol, methanol, acetone, cyclohexanone, petroleum ether, petroleum aromatics, pure benzene, ethyl acetate, toluene, and xylene.

The invention provides an application method of the ethyl oleate miticide, that is: adding water to the ethyl oleate fungicide under stirring at room temperature, and diluting it until the ethyl oleate, that is, the raw material medicine accounts for 0.5-40 wt%. Concentration after spray application.

Compared with the prior art, the present invention has the following beneficial effects:

The invention provides a new type of harmonious bactericide that is safe for humans and animals and friendly to the environment, and has far-reaching significance for ecological environment protection, human health and comprehensive treatment of diseases. Compared with traditional pesticides, the present invention has the following characteristics and advantages:

(1) Ethyl oleate is a natural product, which is non-toxic and easy to degrade, and is friendly and safe to humans, animals and the ecological environment;

(2) Ethyl oleate has easy sources, can be synthesized by esterification reaction, and can also be directly extracted from plants. The method is simple and easy, and can be carried out in large-scale industrial production;

(3) The present invention finds that ethyl oleate has bactericidal biological activity for the first time, and it is formulated into a bactericide for the first time. Through experiments, the control effect on cucumber powdery mildew can reach 93.4%.

detailed description

The present invention will be described in detail below in conjunction with specific embodiments. The following examples will help those skilled in the art to further understand the present invention, but do not limit the present invention in any form. It should be noted that those skilled in the art can make several modifications and improvements without departing from the concept of the present invention. These all belong to the protection scope of the present invention.

Example 1

Take ethyl oleate 37g, dissolve with 10g ethanol solution, add 28g Tween-80, dissolve, according to routine process, make ethyl oleate bactericide of the present invention, then in the prepared ethyl oleate bactericide Dilute with water so that the concentration of ethyl oleate, that is, the bulk drug, is 8%. Finally, the diluted ethyl oleate fungicide was tested for indoor pot plant method on cucumber white powder, and the method was carried out according to the pot test method for powdery mildew in the Bioassay SOP of the National Southern Pesticide Development Center.

The specific method of the test: Spray the medicine evenly on the cucumber seedlings by spraying the stems and leaves; set a blank control without adding the medicine at the same time; dry the test materials in the fume hood or greenhouse for 24 hours. Spray and inoculate the spore suspension of powdery mildew fungus about 24 hours after the chemical treatment, and repeat each treatment 4 times. After the inoculation, the test material was moved to the constant temperature room under the light (26-28°C), and the disease degree was investigated after 7-8 days, and compared with the blank control, the control effect was calculated. Investigate each treatment, its control effect is 74.2%.

Example 2

Take ethyl oleate 60g, dissolve with 230g ethyl acetate, add emulsifying agent etc. 310g therein, according to routine process, make ethyl oleate bactericide of the present invention, then in the prepared ethyl oleate bactericide Dilute with water so that the concentration of ethyl oleate, that is, the bulk drug, is 1%. Finally, the diluted ethyl oleate fungicide was tested against cucumber powdery mildew using the indoor pot method. After the test results were counted, it was concluded that its control effect was 69.64%.

Example 3

Take ethyl oleate 90g, dissolve with 15g methanol, add 25g of emulsifier Span-20 etc. therein, according to routine process, make ethyl oleate bactericide of the present invention, then sterilize in prepared ethyl oleate Add water to dilute in the agent, make the concentration of ethyl oleate that is bulk drug be 26%. Finally, the diluted ethyl oleate fungicide was tested against cucumber powdery mildew using the indoor pot method. After statistics of the test results, it was concluded that its control effect was 80.5%.

Example 4

Take ethyl oleate 200g, dissolve with 12g ethanol, add emulsifying agent Tween-245 therein, 15g such as Span-20, according to routine process, make ethyl oleate fungicide of the present invention, then dilute with water, The compound botanical fungicide formulated with a raw material concentration of 37% was used to conduct a field efficacy test on cucumber powdery mildew with reference to the national pesticide field test guidelines, and the control effect reached 93.4% after 7 days.

Example 5

Take ethyl oleate 409g, dissolve with 285g sherwood oil, add emulsifying agent, synergist, solubilizing agent etc. adjuvant 327g therein, according to routine process, make ethyl oleate fungicide of the present invention, then dilute with water, The compound botanical fungicide formulated with a raw material concentration of 15% was used to conduct a field efficacy test on cucumber powdery mildew with reference to the national pesticide field test guidelines, and the control effect reached 89.1%.

Specific embodiments of the present invention have been described above. It should be understood that the present invention is not limited to the specific embodiments described above, and those skilled in the art may make various changes or modifications within the scope of the claims, which do not affect the essence of the present invention.

Claims (2)

1. a purposes of ethyl oleate, it is characterized in that, ethyl oleate is applied to prepare bactericide; Specific control diseases include any of the following: scab, anthracnose, brown spot, and ring spot of apples, pears, and peaches; powdery mildew, downy mildew, and anthracnose of grapes, watermelons, cucumbers, and melons; wheat Powdery mildew; Rice blast, sheath blight; Vegetable powdery mildew, dry blight, downy mildew, anthracnose; The bactericide is an ethyl oleate bactericide composed of ethyl oleate and conventional auxiliary materials, wherein the quality of ethyl oleate accounts for 0.05%-99% of the quality of ethyl oleate bactericide, and the conventional auxiliary materials account for 0.05%-99% of the quality of ethyl oleate bactericide 1%-99.95% of the quality of ester fungicide; The conventional adjuvant refers to one or more of solubilizers, synergists, emulsifiers, and penetrants; Described solubilizing agent is sodium dodecylbenzenesulfonate, potassium dodecylbenzenesulfonate, polysorbate, polyethylene glycol, polyoxyethyl ether of sorbitol, ligninsulfonate, tea dead, and saponin one or more of The emulsifier is one or more of Spans, Tweens, ethylene glycol esters, propylene glycol esters and/or polyethylene glycol type nonionic surfactants; The synergist is one or more of tea saponin and polyoxyethylene ether; The penetrating agent is azone; The bactericide is one of powder, emulsifiable concentrate, suspension concentrate, dry suspension concentrate, concentrated emulsion, sustained release agent, water emulsion and spray. 2. the application of a fungicide according to claim 1, characterized in that water is added to the ethyl oleate fungicide under normal temperature stirring, so that it is diluted to ethyl oleate, that is, the bulk drug accounts for 0.5-40wt% Concentration after spray application.