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CL2023000909A1 - Materiales y métodos para la unión de siglec-3/cd33 (divisional).. - Google Patents

Materiales y métodos para la unión de siglec-3/cd33 (divisional)..

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Publication number
CL2023000909A1
CL2023000909A1 CL2023000909A CL2023000909A CL2023000909A1 CL 2023000909 A1 CL2023000909 A1 CL 2023000909A1 CL 2023000909 A CL2023000909 A CL 2023000909A CL 2023000909 A CL2023000909 A CL 2023000909A CL 2023000909 A1 CL2023000909 A1 CL 2023000909A1
Authority
CL
Chile
Prior art keywords
methods
siglec
divisional
binding
materials
Prior art date
Application number
CL2023000909A
Other languages
English (en)
Inventor
Singh Sanjaya
Ganesan Rajkumar
Venkataramani Sathyadevi
John Doonan Patrick
Getahun Derebe Mehabaw
S Grewal Iqbal
R Wiehagen Karla
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of CL2023000909A1 publication Critical patent/CL2023000909A1/es

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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • A61K35/14Blood; Artificial blood
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    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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Abstract

La invención proporciona dominios de unión a antígeno que se unen a la proteína CD33 del antígeno de la superficie de células mieloides que comprende los dominios de unión a antígeno que se unen a CD33, polinucleótidos que los codifican, vectores, células huésped, métodos para fabricarlos y usarlos.
CL2023000909A 2020-03-13 2023-03-29 Materiales y métodos para la unión de siglec-3/cd33 (divisional).. CL2023000909A1 (es)

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JP2024533457A (ja) * 2021-09-13 2024-09-12 ヤンセン バイオテツク,インコーポレーテツド がんの治療のためのCD33×Vδ2多重特異性抗体
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