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CL2019002340A1 - Compositions and methods for promoting hair growth with mpc1 inhibitors. - Google Patents

Compositions and methods for promoting hair growth with mpc1 inhibitors.

Info

Publication number
CL2019002340A1
CL2019002340A1 CL2019002340A CL2019002340A CL2019002340A1 CL 2019002340 A1 CL2019002340 A1 CL 2019002340A1 CL 2019002340 A CL2019002340 A CL 2019002340A CL 2019002340 A CL2019002340 A CL 2019002340A CL 2019002340 A1 CL2019002340 A1 CL 2019002340A1
Authority
CL
Chile
Prior art keywords
methods
compositions
hair growth
promoting hair
mpc1
Prior art date
Application number
CL2019002340A
Other languages
Spanish (es)
Inventor
William E Lowry
Heather Christofk
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of CL2019002340A1 publication Critical patent/CL2019002340A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Birds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

EN LA PRESENTE SE PROPORCIONAN MÉTODOS PARA ACELERAR, PROMOVER O RESTAURAR EL CRECIMIENTO DEL CABELLO, QUE COMPRENDEN ADMINISTRARLE A UN SUJETO QUE LO NECESITE UNA CANTIDAD EFICAZ DE UN COMPUESTO DE LA FÓRMULA (I). TAMBIÉN SE PROPORCIONAN COMPOSICIONES QUE COMPRENDEN EL COMPUESTO DE LA FÓRMULA (I).METHODS TO ACCELERATE, PROMOTE, OR RESTORE HAIR GROWTH ARE PROVIDED HEREIN, INCLUDING ADMINISTERING AN EFFECTIVE AMOUNT OF A COMPOUND OF FORMULA (I) TO A SUBJECT IN NEED OF IT. COMPOSITIONS INCLUDING THE COMPOUND OF THE FORMULA (I) ARE ALSO PROVIDED.

CL2019002340A 2016-08-26 2019-08-19 Compositions and methods for promoting hair growth with mpc1 inhibitors. CL2019002340A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662380205P 2016-08-26 2016-08-26
US201762463232P 2017-02-24 2017-02-24

Publications (1)

Publication Number Publication Date
CL2019002340A1 true CL2019002340A1 (en) 2020-01-17

Family

ID=61246282

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2019002340A CL2019002340A1 (en) 2016-08-26 2019-08-19 Compositions and methods for promoting hair growth with mpc1 inhibitors.

Country Status (3)

Country Link
CL (1) CL2019002340A1 (en)
PH (1) PH12019501722A1 (en)
WO (1) WO2018039612A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112019015552A2 (en) 2017-02-24 2020-03-17 The Regents Of The University Of California COMPOSITIONS AND METHODS TO PROMOTE HAIR GROWTH WITH MPC INHIBITORS1
MX2019015475A (en) 2017-06-30 2020-02-19 Univ California Compositions and methods for modulating hair growth.
WO2019161272A1 (en) 2018-02-15 2019-08-22 North Carolina State University Synthesis of micron and nanoscale carbon spheres and structures using hydrothemal carbonization
EP3906240A4 (en) * 2019-01-02 2022-10-05 The Regents of the University of California COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH
JP7497974B2 (en) * 2019-12-20 2024-06-11 株式会社 資生堂 Method for activating skin stem cells by suppressing MPC1 and skin stem cell activator
US20240327400A1 (en) * 2020-06-30 2024-10-03 The Regents Of The University Of California Compositions and methods for modulating hair growth

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US162A (en) 1837-04-17 Island
US5212A (en) 1847-07-31 Richard m
US4172896A (en) 1978-06-05 1979-10-30 Dainippon Pharmaceutical Co., Ltd. Methane-sulfonamide derivatives, the preparation thereof and composition comprising the same
US4911920A (en) 1986-07-30 1990-03-27 Alcon Laboratories, Inc. Sustained release, comfort formulation for glaucoma therapy
FR2588189B1 (en) 1985-10-03 1988-12-02 Merck Sharp & Dohme LIQUID-GEL PHASE TRANSITION PHARMACEUTICAL COMPOSITION
EP0495421B1 (en) 1991-01-15 1996-08-21 Alcon Laboratories, Inc. Use of carrageenans in topical ophthalmic compositions
GB9217295D0 (en) 1992-08-14 1992-09-30 Wellcome Found Controlled released tablets
US5358970A (en) 1993-08-12 1994-10-25 Burroughs Wellcome Co. Pharmaceutical composition containing bupropion hydrochloride and a stabilizer
GB9315856D0 (en) 1993-07-30 1993-09-15 Wellcome Found Stabilized pharmaceutical
US5541231A (en) 1993-07-30 1996-07-30 Glaxo Wellcome Inc. Stabilized Pharmaceutical
JP2002501892A (en) 1998-01-29 2002-01-22 セプラコア インコーポレーテッド Pharmaceutical use of optically pure (-)-viewpropion
EP2847356A4 (en) * 2012-05-10 2015-08-05 Univ Utah Res Found COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF A MITOCHONDRIAL PYRUVATE CARRIER
US20160250249A1 (en) * 2013-10-03 2016-09-01 Inserm ( Institute National De Lasanté Et De La Re Cherche Médicale) Methods and pharmaceutical compositions for modulating autophagy in a subject in need thereof

Also Published As

Publication number Publication date
WO2018039612A1 (en) 2018-03-01
PH12019501722A1 (en) 2020-06-15

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